The Tien Group

Boston University

Department of Biomedical Engineering

44 Cummington Mall

Boston, MA 02215

We are an interdisciplinary group of researchers who invent new types of biomaterials, for uses that range from basic studies of quantitative physiology to clinical applications in regenerative medicine.  Of particular interest are microfluidic materials whose internal geometries mimic the organization of native vascular networks.  With these materials, we seek to solve one of the long-standing challenges in tissue engineering: how to form clinically relevant volumes of tissue that are nourished and drained by functional microvessels.  We are currently in our thirteenth year at Boston University.

Questions of current interest include:

·         How can one synthesize and vascularize three-dimensional (3D) microfluidic materials?

·         What quantitative principles govern functional vascularization of biomaterials?  Can one distill these principles into a computer algorithm for rational scaffold design?

·         How does one scale up vascularized materials to clinically relevant sizes?  How do such materials behave when grafted in vivo?

To address these questions, we develop unconventional methods to organize vascular and non-vascular cells and extracellular components into perfused, micropatterned tissues.  We use traditional techniques of microvascular physiology (along with a healthy mixture of ideas from vascular cell biology, transport phenomena, biomechanics, and numerical modeling) to analyze, predict, and control the behavior of these tissues.

Below, we invite you to read about the group and its research interests, publications, and resources.  For further information, please contact us directly.

 

GROUP INFORMATION

Principal Investigator:          Joe Tien

Address:                                  We are located on the 7th floor of the Engineering Research Building (44 Cummington Mall), in rooms 713, 715, and 717. [Map]

Phone:                                    (617) 358-3055 [Joe’s office—ERB 717]

                                                (617) 358-2831 [Lab and lounge—ERB 715 & 713]

Fax:                                         (617) 358-2835

 

RESEARCH INTERESTS

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: PECAMMechanics of vascularization

Much of our recent work is focused on understanding how vascularization of microfluidic scaffolds occurs and what factors control its long-term success.  We have found that the microfluidic structure of a scaffold is important in controlling the initial formation of open vessels, but it is insufficient to guarantee sustained perfusion.  Through a combination of experimental and computational studies, we have shown that mechanical stresses at the cell-scaffold interface determine whether the vascular lining remains adherent or detaches over time.  We have begun to apply this physical theory of vascularization to a variety of challenging problems, including the vascularization of capillary-scale channels and the formation of functional lymphatic microvessels in which the mechanical stresses are inherently destabilizing.

 

 

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: D:\jlab\webpage\index_files\PDMSstamp.jpgTechniques for patterning biological materials

We have a long-standing interest in inventing new techniques for patterning biological materials.  In fact, our work on vascularization is based on subtractive methods that we developed in-house to create single channels and entire networks within hydrogels of extracellular matrix.  We are always interested in patterning scaffolds with ever finer resolution, greater three-dimensional connectivity, and larger network sizes.  Current efforts are focused on specific applications, including the development of valves that can actively pump fluids and the creation of large-scale microfluidic scaffolds suitable for composite tissue engineering.

 

 

MEMBERS (Current in bold)

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: joe'

Joe Tien

     [BME page]

     [CV]

     [Google Scholar]

 

jtien | bu_edu

 

 

 

 

Principal investigator

 

 

 

 

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: beccaThompson_14'

Rebecca Thompson

 

 

 

 

rthomp | bu_edu

 

 

 

 

Undergraduate researcher

 

 

 

 

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Nelson

Nelson Boland

 

 

 

 

nfboland | bu_edu

 

 

 

 

Undergraduate researcher

 

 

 

 

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Gil's%20Photo

Gil Covarrubias

 

 

 

 

gcova | bu_edu

 

 

 

 

Undergraduate researcher

 

 

 

 

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Photo%20-%20Tyler%20Ryan

Tyler Ryan

 

 

 

 

ryanty | bu_edu

 

 

 

 

Undergraduate researcher

 

 

 

 

Raleigh Linville

 

 

 

 

raleigh | bu_edu

 

 

 

 

Undergraduate researcher

 

 

 

 

Jing Xu

 

 

 

 

jxu852 | bu_edu

 

 

 

 

Undergraduate researcher

 

 

 

 

 

James Truslow

     (2006-2013)

 

 

 

 

jtruslow | bu_edu

 

 

 

 

 

Ph.D. thesis: "Design and Analysis of Engineered Microvasculature via Computational Methods"

M.S. thesis: "Drainage Systems That Maintain Transmural Pressure in Engineered Microvascular Tissue"

 

Research scientist, Draper Labs

 

Keith Wong

     (2007-2012)

    

 

 

 

kwong18 | partners_org

khkwong |   

mgh_harvard_edu

whk.keith | gmail_com

 

 

Ph.D. thesis: "Normalization of Microvascular Physiology in Engineered Microvessels via Cyclic Adenosine Monophosphate Supplementation and Artificial Lymphatic Drainage"

 

Postdoctoral fellow with Mehmet Toner (Center for Engineering in Medicine, MGH/Harvard)

 

Kelvin Chan

     (2011-2012)

 

 

lordkelvin | gmail_com

 

 

 

M.S. thesis: "Genipin Crosslinked Collagen Microfluidic Scaffolds Form Stable Microvessels In Vitro Using Human Endothelial Cells"

 

Medical student, Albert Einstein College of Medicine

 

Gavrielle Price

     (2004-2009)

 

 

 

gaviprice | gmail_com

 

 

 

Ph.D. thesis: "Mechanical and Chemical Control of Barrier in Engineered Microvessels"

 

Postdoctoral fellow with Martin Yarmush (Center for Engineering in Medicine, MGH/Harvard)

 

Andrew Golden

     (2002-2008)

 

gol8dy | yahoo_com

 

 

Ph.D. thesis: "Microfluidic Hydrogels for Microvascular Tissue Engineering"

 

Research scientist, LeMaitre Vascular

 

Kenneth Chrobak

     (2003-2007)

 

 

kchrobak | alum_bu_edu

 

 

Ph.D. thesis: "Formation of Perfused Microvessels In Vitro, and Their Use as Models of Barrier Function"

 

Research manager, Baxter Healthcare

 

Min Tang

     (2002-2005)

 

 

min.tang-schomer |

tufts_edu

 

 

Ph.D. thesis: "In Vitro Engineering of a Microvascular Network"

 

Postdoctoral fellow with David Kaplan (Tufts University, Department of Biomedical Engineering)

 

Brent Coisman (2013-2014)

 

B.S., biomedical engineering, Boston University (2014)

 

Aimal Khankhel (2011-2013)

 

 

 

Research scientist with Mehmet Toner (Center for Engineering in Medicine, MGH/Harvard)

 

Ben Cohen (2012)

 

Doctoral student in biomedical engineering, Cornell University

 

Rachel Roesch (2011)

 

Doctoral student in chemistry, University of Pennsylvania

 

Jason Pui (2011-2012)

 

Engineer, Accellent

 

Alex Leung (2009-2011)

 

Medical student, Boston University

 

Chitrangada Acharya (2010)

 

Research scientist, Allied Innovative Systems

 

Stephanie Steichen (2008)

 

Doctoral student in biomedical engineering, UT Austin

 

Kim Waller (2007-2008)

 

 

Ph.D., biomedical engineering, Brown University (2013)

Postdoctoral fellow, Rhode Island Hospital

 

Russell Condie (2006)

 

Doctoral student in biomedical engineering, University of Utah

 

Hillary Eggert (2004)

 

Carthage College, Biology

 

Cate McCullough (2003)

 

 

M.S., bioengineering, Stanford University (2007)

Executive director, Resources for Medical Education and Collaboration

 

Wajd Al-Holou (2002)

 

 

 

M.D., University of Michigan (2009)

     Specialty: neurosurgery

 

Brandon Markway (2002)

 

 

Ph.D., biomedical engineering, Oregon Health and Science University (2010)

Postdoctoral fellow with Brian Johnstone (OHSU, Orthopaedics & Rehabilitation)

 

PUBLICATIONS

51. Ozsun, O., Thompson, R.L., Ekinci, K.L. & Tien, J., Non-invasive mapping of interstitial fluid pressure in microscale tissues. Integr. Biol., in press.

50. Piotrowski, A.S., Simi, A.K., Pang, M.F., Tien, J. & Nelson, C.M. A three-dimensional culture model to study how fluid pressure and flow affect the behavior of aggregates of epithelial cells. In Mammary Gland Development (Methods in Molecular Biology series) (eds. Martin, F. & Stein, T.), in press (Humana Press, New York, NY).

49. Tien, J., Microfluidic approaches for engineering vasculature. Curr. Opin. Chem. Eng. 3, 36-41 (2014). [PDF]

48. Chan, K.L.S., Khankhel, A.H., Thompson, R.L., Coisman, B.J., Wong, K.H.K., Truslow, J.G. & Tien, J., Crosslinking of collagen scaffolds promotes blood and lymphatic vascular stability. J. Biomed. Mater. Res. A 102, 3186-3195 (2014). [PDF]

47. Tien, J. & Nelson, C.M., Microstructured extracellular matrices in tissue engineering and development, an update. Ann. Biomed. Eng. 42, 1413-1423 (2014). [PDF]

46. Wong, K.H.K., Truslow, J.G., Khankhel, A.H. & Tien, J. Biophysical mechanisms that govern the vascularization of microfluidic scaffolds. In Vascularization: Regenerative Medicine and Tissue Engineering (ed. Brey, E.M.), pp. 109-124 (CRC Press, Boca Raton, FL, 2014). [PDF]

45. Truslow, J.G. & Tien, J., Determination of vascular permeability coefficients under slow lumenal filling. Microvasc. Res. 90, 117-120 (2013). [PDF]

44. Wong, K.H.K., Truslow, J.G., Khankhel, A.H., Chan, K.L.S. & Tien, J., Artificial lymphatic drainage systems for vascularized microfluidic scaffolds. J. Biomed. Mater. Res. A 101, 2181-2190 (2013). [PDF]

43. Tien, J., Wong, K.H.K. & Truslow, J.G. Vascularization of microfluidic hydrogels. In Microfluidic Cell Culture Systems (eds. Bettinger, C.J., Borenstein, J.T. & Tao, S.L.), pp. 205-221 (Elsevier, Oxford, U.K., 2013). [PDF]

42. Tien, J., Truslow, J.G. & Nelson, C.M., Modulation of invasive phenotype by interstitial pressure-driven convection in aggregates of human breast cancer cells. PLoS One 7, e45191 (2012). [Corrected PDF + Supporting Information]

41. Leung, A.D., Wong, K.H.K. & Tien, J., Plasma expanders stabilize human microvessels in microfluidic scaffolds. J. Biomed. Mater. Res. A 100, 1815–1822 (2012). [PDF]

40. Wong, K.H.K., Chan, J.M., Kamm, R.D. & Tien, J., Microfluidic models of vascular functions. Annu. Rev. Biomed. Eng. 14, 205–230 (2012). [PDF]

39. Truslow, J.G. & Tien, J., Perfusion systems that minimize vascular volume fraction in engineered tissues. Biomicrofluidics 5, 022201 (2011). [PDF]

38. Price, G.M. & Tien, J. Methods for forming human microvascular tubes in vitro and measuring their macromolecular permeability. In Biological Microarrays (Methods in Molecular Biology, vol. 671) (eds. Khademhosseini, A., Suh, K.-Y. & Zourob, M.), pp. 281-293 (Humana Press, Totowa, NJ, 2011). [PDF]

37. Price, G.M., Wong, K.H.K., Truslow, J.G., Leung, A.D., Acharya, C. & Tien, J., Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels. Biomaterials 31, 6182-6189 (2010). [PDF]

36. Wong, K.H.K., Truslow, J.G. & Tien, J., The role of cyclic AMP in normalizing the function of engineered human blood microvessels in microfluidic collagen gels. Biomaterials 31, 4706-4714 (2010). [PDF] [Movie]

35. Truslow, J.G., Price, G.M. & Tien, J., Computational design of drainage systems for vascularized scaffolds. Biomaterials 30, 4435-4443 (2009). [PDF]

34. Price, G.M. & Tien, J. Subtractive methods for forming microfluidic gels of extracellular matrix proteins. In Microdevices in Biology and Engineering (eds. Bhatia, S.N. & Nahmias, Y.), pp. 235-248 (Artech House, Boston, MA, 2009). [PDF]

33. Price, G.M., Chu, K.K., Truslow, J.G., Tang-Schomer, M.D., Golden, A.P., Mertz, J. & Tien, J., Bonding of macromolecular hydrogels using perturbants. J. Am. Chem. Soc. 130, 6664-6665 (2008). [PDF + Supporting Information] [Movies]

32. Price, G.M., Chrobak, K.M. & Tien, J., Effect of cyclic AMP on barrier function of human lymphatic microvascular tubes. Microvasc. Res. 76, 46-51 (2008). [PDF]

31. Golden, A.P. & Tien, J., Fabrication of microfluidic hydrogels using molded gelatin as a sacrificial element. Lab Chip 17, 720-725 (2007). [PDF]

30. Nelson, C.M. & Tien, J., Microstructured extracellular matrices in tissue engineering and development. Curr. Opin. Biotechnol. 17, 518-523 (2006). [PDF]

29. Chrobak, K.M., Potter, D.R. & Tien, J., Formation of perfused, functional microvascular tubes in vitro. Microvasc. Res. 71, 185-196 (2006). [PDF] [Movies]

28. Tien, J., Golden, A.P. & Tang, M.D. Engineering of blood vessels. In Microvascular Research: Biology and Pathology, Vol. 2 (eds. Shepro, D. & D'Amore, P.A.), pp. 1087-1093 (Elsevier Academic Press, San Diego, CA, 2006). [PDF]

27. Tang, M.D., Golden, A.P. & Tien, J., Fabrication of collagen gels that contain patterned, micrometer-scale cavities. Adv. Mater. 16, 1345-1348 (2004). [PDF]

26. Gray, D.S., Tien, J. & Chen, C.S., High conductivity elastomeric electronics. Adv. Mater. 16, 393-397 (2004). [PDF]

25. Chen, C.S., Tan, J.L. & Tien, J., Mechanotransduction at cell-matrix and cell-cell contacts. Annu. Rev. Biomed. Eng. 6, 275-302 (2004). [PDF]

24. Tang, M.D., Golden, A.P. & Tien, J., Molding of three-dimensional microstructures of gels. J. Am. Chem. Soc. 125, 12988-12989 (2003). [PDF]

23. Gray, D.S., Tien, J. & Chen, C.S., Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus. J. Biomed. Mater. Res. A 66, 605-614 (2003). [PDF]

22. Tan, J.L., Tien, J., Pirone, D.M., Gray, D.S., Bhadriraju, K. & Chen, C.S., Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc. Natl. Acad. Sci. USA 100, 1484-1489 (2003). [PDF]

21. Clark, T.D., Ferigno, R., Tien, J., Paul, K.E. & Whitesides, G.M., Template-directed self-assembly of 10-μm-sized hexagonal plates. J. Am. Chem. Soc. 124, 5419-5426 (2002). [PDF]

20. Tien, J., Nelson, C.M. & Chen, C.S., Fabrication of aligned microstructures with a single elastomeric stamp. Proc. Natl. Acad. Sci. USA 99, 1758-1762 (2002). [PDF]

19. Tien, J. & Chen, C.S., Patterning the cellular microenvironment. IEEE Eng. Med. Biol. 21, 95-98 (2002). [PDF]

18. Tan, J.L., Tien, J. & Chen, C.S., Microcontact printing of proteins on mixed self-assembled monolayers. Langmuir 18, 519-523 (2002). [PDF]

17. Tien, J. & Chen, C.S. Microarrays of cells. In Methods of Tissue Engineering (eds. Atala, A. & Lanza, R.), pp. 113-120 (Academic Press, San Diego, CA, 2001).

16. Bowden, N., Tien, J., Huck, W.T.S. & Whitesides, G.M. Mesoscale self-assembly: the assembly of micron- and millimeter-sized objects using capillary forces. In Supramolecular Organization and Materials Design (eds. Jones, W. & Rao, C.N.R.), pp. 103-145 (Cambridge University Press, New York, NY, 2001).

15. Clark, T.D., Tien, J., Duffy, D.C., Paul, K.E. & Whitesides, G.M., Self-assembly of 10-μm-sized objects into ordered three-dimensional arrays. J. Am. Chem. Soc. 123, 7677-7682 (2001). [PDF]

14. Gracias, D.H., Tien, J., Breen, T.L., Hsu, C. & Whitesides, G.M., Forming electrical networks in three dimensions by self-assembly. Science 289, 1170-1172 (2000). [PDF]

13. Dike, L.E., Chen, C.S., Mrksich, M., Tien, J., Whitesides, G.M. & Ingber, D.E., Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates. In Vitro Cell. Dev. Biol. Anim. 35, 441-448 (1999). [PDF]

12. Deng, T., Tien, J., Xu, B. & Whitesides, G.M., Using patterns in microfiche as photomasks in 10-μm-scale microfabrication. Langmuir 15, 6575-6581 (1999). [PDF]

11. Breen, T.L., Tien, J., Oliver, S.R.J., Hadzic, T. & Whitesides, G.M., Design and self-assembly of open, regular, 3D mesostructures. Science 284, 948-951 (1999). [PDF]

10. Lahiri, J., Isaacs, L., Tien, J. & Whitesides, G.M., A strategy for the generation of surfaces presenting ligands for studies of binding based on an active ester as a common reactive intermediate. Anal. Chem. 71, 777-790 (1999). [PDF]

9. Tien, J., Breen, T.L. & Whitesides, G.M., Crystallization of millimeter-scale objects with use of capillary forces. J. Am. Chem. Soc. 120, 12670-12671 (1998). [PDF]

8. Huck, W.T.S., Tien, J. & Whitesides, G.M., Three-dimensional mesoscale self-assembly. J. Am. Chem. Soc. 120, 8267-8268 (1998). [PDF]

7. Marzolin, C., Terfort, A., Tien, J. & Whitesides, G.M., Patterning of a polysiloxane precursor to silicate glasses by microcontact printing. Thin Solid Films 315, 9-12 (1998). [PDF]

6. Tien, J., Xia, Y. & Whitesides, G.M. Microcontact printing of SAMs. In Self-Assembled Monolayers of Thiols (Thin Films, vol. 24) (ed. Ulman, A.), pp. 227-250 (Academic Press, San Diego, CA, 1998).

5. Xia, Y., Venkateswaran, N., Qin, D., Tien, J. & Whitesides, G.M., Use of electroless silver as the substrate in microcontact printing of alkanethiols and its application in microfabrication. Langmuir 14, 363-371 (1998). [PDF]

4. Mrksich, M., Dike, L.E., Tien, J., Ingber, D.E. & Whitesides, G.M., Using microcontact printing to pattern the attachment of mammalian cells to self-assembled monolayers of alkanethiolates on transparent films of gold and silver. Exp. Cell Res. 235, 305-313 (1997). [PDF]

3. Tien, J., Terfort, A. & Whitesides, G.M., Microfabrication through electrostatic self-assembly. Langmuir 13, 5349-5355 (1997). [PDF]

2. Xia, Y., Tien, J., Qin, D. & Whitesides, G.M., Non-photolithographic methods for fabrication of elastomeric stamps for use in microcontact printing. Langmuir 12, 4033-4038 (1996). [PDF]

1. Shaw, G.L. & Tien, J., Energy levels of quark atoms. Phys. Rev. D 47, 5075-5078 (1993). [PDF]

 

FUNDING

Non-Invasive Measurement of Vascular Cell Adhesion to Biomaterials (BU Dean’s Catalyst Award)

Active Biomaterials (BU Materials Science and Engineering Innovation Grant)

Effect of Interstitial Pressure on Epithelial Invasion from Human Mammary Ducts (DoD/Army W81XWH-09-1-0565)

Engineering Functional Lymphatic Networks In Vitro (NIH/NHLBI R21 HL092335)

Synthesis and Characterization of Patterned Microvascular Networks (NIH/NIBIB R01 EB005792)

Self-Assembly of Mesostructured Biomaterials (NIH/NIBIB R21 EB003157)

In Vitro Synthesis of a Microvascular Network (NIH/NIBIB R21 EB002228)

Use of Microfabrication and Self-Assembly in Tissue Engineering (Whitaker Foundation RG-02-0344)

Dynamic Substrates for Cell Culture (BU Special Program for Research Initiation Grants)

Self-Assembly of Gels (BU Provost’s Innovation Fund)

Response of Endothelial Cells to Cell-Cell Contact (NIH/NHLBI F32 HL010486)

 

LINKS

How to join our research program:

·         Postdoctoral fellows:

Interested postdoctoral candidates should send us a detailed cover letter, CV, and a list of three professional references.  We look for candidates with a robust track record of publication and innovation.

·         Graduate students:

Graduate students must apply through one of the doctoral programs listed below—we are especially interested in applicants with a strong quantitative background and excellent technical skills:

Department of Biomedical Engineering

NIH Training Program in Quantitative Biology and Physiology (for BME program)

Program in Molecular Biology, Cell Biology, and Biochemistry

Division of Materials Science and Engineering

Late Entry Accelerated Program (LEAP) in Biomedical Engineering

MD/PhD program at Boston University School of Medicine

·         Undergraduate students:

Undergraduate students should send us a brief explanatory letter, transcript, and description of any prior research experience.  We seek students who learn quickly, work hard, and have impeccable ethics.

Resources at BU:

Core facilities (lithography, imaging, and materials characterization) in the Department of Biomedical Engineering

Core facilities (flow cytometry, microarrays, transgenics, etc.) at the Medical Center

Core facilities (lithography, SEM) in the Photonics Center

Library catalog

Collaborators:

Celeste Nelson, Department of Chemical Engineering, Princeton University

Jerome Mertz, Department of Biomedical Engineering, Boston University

Kamil Ekinci, Department of Mechanical Engineering, Boston University

Chris Carman, Center for Vascular Biology Research, BIDMC/Harvard Medical School

Databases and analytical software:

PubMed

ISI Web of Knowledge (here, for BU users)

Horst Ibelgaufts’ COPE (giant cytokine index)

The Lipid Library (with focus on bioactive lipids)

NIST database on thermodynamics of enzyme-catalyzed reactions

Atlas of microsurgery

The Pathology Guy

Abbreviations of journal titles

Statistical tests

2D and 3D curve-fitting

Matrix calculations

Journals of particular relevance to microcirculation:

American Journal of Physiology – Heart and Circulatory Physiology

Circulation

Circulation Research

Journal of Experimental Medicine

Lymphatic Research and Biology

Lymphology

Microcirculation

Microvascular Research

Organizations:

National Institutes of Health (NIH)

National Institute of Biomedical Imaging and Bioengineering (NIBIB)

National Heart, Lung, and Blood Institute (NHLBI)

National Cancer Institute (NCI)

Information on funded NIH grants: RePORTER database and success rates

Information on deadlines, study sections, special emphasis panels, funding strategies, and opportunities

National Science Foundation (NSF)

Whitaker Foundation

Biomedical Engineering Society (BMES)

American Heart Association (AHA)

The Microcirculatory Society

Lymphatic Research Foundation

Organ Procurement and Transplantation Network (OPTN)

NHS Blood and Transplant (NHSBT)

Bone Marrow Donors Worldwide

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: logo_MOD

Upcoming events:

Biology Week (list of Boston-area seminars)

Gordon Research Conferences

Keystone Symposia

Courses at the Marine Biology Laboratory/Woods Hole

Courses at Cold Spring Harbor Laboratory

BMES 2014 Annual Meeting (Oct 22-25, 2014; San Antonio, TX)

2015 BMES-CMBE Conference (Jan 6-10, 2015; St. Thomas, U.S. Virgin Islands)

Experimental Biology 2015 (Mar 28–Apr 1, 2015; Boston, MA)

 

[Copyright © 2006-2014 by the Tien Group.]

Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: Description: free web page counters