• Comparing brief stress management courses in a community sample: mindfulness skills and progressive muscle relaxation

    Type Journal Article
    Author John D Agee
    Author Sharon Danoff-Burg
    Author Christoffer A Grant
    Abstract This study sought to compare a five-week mindfulness meditation (MM) course to a five-week course that taught progressive muscle relaxation (PMR). Forty-three adults from the community were randomly assigned to either MM (n = 19) or PMR (n = 24) courses after responding to flyers and other advertisements for a free stress management course. Mindfulness meditation participants practiced meditation significantly more often than PMR participants practiced relaxation during the intervention period (F[1, 43] = 7.42; P < .05). Interestingly, the two conditions did not differ significantly in their posttreatment levels of relaxation or mindfulness. Although there were no differences between groups on any of the primary outcome measures, across both treatment conditions there were statistically significant reductions from pretreatment to posttreatment in general psychological distress. Thus, although MM did not emerge as clearly superior to PMR, results of this study suggest that a brief mindfulness skills course may be effective for stress management.
    Publication Explore (New York, N.Y.)
    Volume 5
    Issue 2
    Pages 104-109
    Date 2009 Mar-Apr
    Journal Abbr Explore (NY)
    DOI 10.1016/j.explore.2008.12.004
    ISSN 1550-8307
    Short Title Comparing brief stress management courses in a community sample
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19272581
    Accessed Sat Sep 26 15:22:28 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19272581
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adult
    • Aged
    • Female
    • Humans
    • Male
    • Meditation
    • Middle Aged
    • Mind-Body Relations (Metaphysics)
    • Muscle Relaxation
    • Personal Satisfaction
    • Pilot Projects
    • Psychotherapy, Group
    • Relaxation Therapy
    • Self Care
    • Stress, Psychological
    • Treatment Outcome
    • Young Adult

    Notes:

    • This study sought to compare a five-week mindfulness meditation (MM) course to a five-week course that taught progressive muscle relaxation (PMR). Forty-three adults from the community were randomly assigned to either MM (n = 19) or PMR (n = 24) courses after responding to flyers and other advertisements for a free stress management course. Mindfulness meditation participants practiced meditation significantly more often than PMR participants practiced relaxation during the intervention period (F[1, 43] = 7.42; P < .05). Interestingly, the two conditions did not differ significantly in their posttreatment levels of relaxation or mindfulness. Although there were no differences between groups on any of the primary outcome measures, across both treatment conditions there were statistically significant reductions from pretreatment to posttreatment in general psychological distress. Thus, although MM did not emerge as clearly superior to PMR, results of this study suggest that a brief mindfulness skills course may be effective for stress management.

  • Systematic review of the efficacy of meditation techniques as treatments for medical illness

    Type Journal Article
    Author Albert J Arias
    Author Karen Steinberg
    Author Alok Banga
    Author Robert L Trestman
    Abstract Meditative techniques are sought frequently by patients coping with medical and psychological problems. Because of their increasingly widespread appeal and use, and the potential for use as medical therapies, a concise and thorough review of the current state of scientific knowledge of these practices as medical interventions was conducted. PURPOSE: To systematically review the evidence supporting efficacy and safety of meditative practices in treating illnesses, and examine areas warranting further study. Studies on normal healthy populations are not included. METHODS: Searches were performed using PubMed, PsycInfo, and the Cochrane Database. Keywords were Meditation, Meditative Prayer, Yoga, Relaxation Response. Qualifying studies were reviewed and independently rated based on quality by two reviewers. Mid-to-high-quality studies (those scoring above 0.65 or 65% on a validated research quality scale) were included. RESULTS: From a total of 82 identified studies, 20 randomized controlled trials met our criteria. The studies included 958 subjects total (397 experimentally treated, 561 controls). No serious adverse events were reported in any of the included or excluded clinical trials. Serious adverse events are reported in the medical literature, though rare. The strongest evidence for efficacy was found for epilepsy, symptoms of the premenstrual syndrome and menopausal symptoms. Benefit was also demonstrated for mood and anxiety disorders, autoimmune illness, and emotional disturbance in neoplastic disease. CONCLUSIONS: The results support the safety and potential efficacy of meditative practices for treating certain illnesses, particularly in nonpsychotic mood and anxiety disorders. Clear and reproducible evidence supporting efficacy from large, methodologically sound studies is lacking.
    Publication Journal of Alternative and Complementary Medicine (New York, N.Y.)
    Volume 12
    Issue 8
    Pages 817-832
    Date Oct 2006
    Journal Abbr J Altern Complement Med
    DOI 10.1089/acm.2006.12.817
    ISSN 1075-5535
    URL http://www.ncbi.nlm.nih.gov/pubmed/17034289
    Accessed Sat Sep 5 13:03:49 2009
    Library Catalog NCBI PubMed
    Extra PMID: 17034289
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Chronic Disease
    • Holistic Health
    • Humans
    • Meditation
    • Mental Healing
    • Mind-Body Relations (Metaphysics)
    • Randomized Controlled Trials as Topic
    • Research Design

    Notes:

    • Meditative techniques are sought frequently by patients coping with medical and psychological problems. Because of their increasingly widespread appeal and use, and the potential for use as medical therapies, a concise and thorough review of the current state of scientific knowledge of these practices as medical interventions was conducted. Purpose: To systematically review the evidence supporting efficacy and safety of meditative practices in treating illnesses, and examine areas warranting further study. Studies on normal healthy populations are not included. Methods: Searches were performed using PubMed, PsycInfo, and the Cochrane Database. Keywords were Meditation, Meditative Prayer, Yoga, Relaxation Response. Qualifying studies were reviewed and independently rated based on quality by two reviewers. Mid-to-high-quality studies (those scoring above 0.65 or 65% on a validated research quality scale) were included. Results: From a total of 82 identified studies, 20 randomized controlled trials met our criteria. The studies included 958 subjects total (397 experimentally treated, 561 controls). No serious adverse events were reported in any of the included or excluded clinical trials. Serious adverse events are reported in the medical literature, though rare. The strongest evidence for efficacy was found for epilepsy, symptoms of the premenstrual syndrome and menopausal symptoms. Benefit was also demonstrated for mood and anxiety disorders, autoimmune illness, and emotional disturbance in neoplastic disease. Conclusions: The results support the safety and potential efficacy of meditative practices for treating certain illnesses, particularly in nonpsychotic mood and anxiety disorders. Clear and reproducible evidence supporting efficacy from large, methodologically sound studies is lacking.

  • In search of inner wisdom: guided mindfulness meditation in the context of suicide

    Type Journal Article
    Author Liora Birnbaum
    Author Aiton Birnbaum
    Abstract Spiritual concerns are highly relevant, but often ignored, in psychotherapy in general and in suicide in particular. This article presents Internet data and clinical case material bearing on the topic, and describes an innovative therapeutic intervention administered in a group-workshop format with suicide survivors and mental health professionals. The technique incorporates relaxation and mindfulness meditation, with the addition of guided meditation in search of inner wisdom. Results of the group intervention are described and illustrated. Many participants reported a significant positive experience including connection to knowledge that was highly relevant to them in their current state of life. Whether such insights were experienced as coming from within (a deeper part of the self) or from an external source (a guiding figure or presence), indications are that guided meditation can be a powerful resource for therapists and their clients, suicidal and otherwise. Possible applications in diverse populations and settings, as well as the need for further research, are discussed.
    Publication TheScientificWorldJournal
    Volume 4
    Pages 216-227
    Date Mar 18, 2004
    Journal Abbr ScientificWorldJournal
    DOI 10.1100/tsw.2004.17
    ISSN 1537-744X
    Short Title In search of inner wisdom
    URL http://www.ncbi.nlm.nih.gov/pubmed/15105961
    Accessed Fri Nov 13 12:50:37 2009
    Library Catalog NCBI PubMed
    Extra PMID: 15105961
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adult
    • Female
    • Humans
    • Knowledge
    • Male
    • Meditation
    • Middle Aged
    • religion
    • spirituality
    • Suicide

    Notes:

    • Spiritual concerns are highly relevant, but often ignored, in psychotherapy in general and in suicide in particular. This article presents Internet data and clinical case material bearing on the topic, and describes an innovative therapeutic intervention administered in a group-workshop format with suicide survivors and mental health professionals. The technique incorporates relaxation and mindfulness meditation, with the addition of guided meditation in search of inner wisdom. Results of the group intervention are described and illustrated. Many participants reported a significant positive experience including connection to knowledge that was highly relevant to them in their current state of life. Whether such insights were experienced as coming from within (a deeper part of the self) or from an external source (a guiding figure or presence), indications are that guided meditation can be a powerful resource for therapists and their clients, suicidal and otherwise. Possible applications in diverse populations and settings, as well as the need for further research, are discussed.

  • Defining a Complex Intervention: The Development of Demarcation Criteria for "Meditation"

    Type Journal Article
    Author Kenneth Bond
    Author Maria B. Ospina
    Author Nicola Hooton
    Author Liza Bialy
    Author Donna M. Dryden
    Author Nina Buscemi
    Author David Shannahoff-Khalsa
    Author Jeffrey Dusek
    Author Linda E. Carlson
    Abstract The authors used a 5-round Delphi study with a panel of 7 experts in meditation research to achieve agreement on a set of criteria for a working definition of "meditation" for use in a comprehensive systematic review of the therapeutic use of meditation. Participants agreed that essential to a meditation practice is its use of (a) a defined technique, (b) logic relaxation, and (c) a self-induced state. Participants also agreed that a meditation practice may (d) involve a state of psychophysical relaxation somewhere in the process; (e) use a self-focus skill or anchor; (f) involve an altered state/mode of consciousness, mystic experience, enlightenment or suspension of logical thought processes; (g) be embedded in a religious/spiritual/philosophical context; or (h) involve an experience of mental silence. The results of this study provide insight into the challenges faced by researchers who want to demarcate meditative practices from nonmeditative practices, and they describe an approach to this problem that may prove useful for researchers trying to operationalize meditation in the context of comparative research.
    Publication Psychology of Religion and Spirituality
    Volume 1
    Issue 2
    Pages 129-137
    Date May 2009
    DOI 10.1037/a0015736
    ISSN 1941-1022
    Short Title Defining a Complex Intervention
    URL http://www.sciencedirect.com/science/article/B9846-4WKH6C3-5/2/509e26c0ce84ca65c2c2ef1f2ad57eb2
    Accessed Mon Mar 28 19:14:39 2011
    Library Catalog ScienceDirect
    Date Added Thu Sep 29 09:07:00 2011
    Modified Thu Sep 29 09:07:00 2011

    Tags:

    • CAM
    • characteristics
    • Meditation
    • mind-body techniques
    • yoga

    Notes:

    • The authors used a 5-round Delphi study with a panel of 7 experts in meditation research to achieve agreement on a set of criteria for a working definition of “meditation” for use in a comprehensive systematic review of the therapeutic use of meditation. Participants agreed that essential to a meditation practice is its use of (a) a defined technique, (b) logic relaxation, and (c) a self-induced state. Participants also agreed that a meditation practice may (d) involve a state of psychophysical relaxation somewhere in the process; (e) use a self-focus skill or anchor; (f) involve an altered state/mode of consciousness, mystic experience, enlightenment or suspension of logical thought processes; (g) be embedded in a religious/spiritual/philosophical context; or (h) involve an experience of mental silence. The results of this study provide insight into the challenges faced by researchers who want to demarcate meditative practices from nonmeditative practices, and they describe an approach to this problem that may prove useful for researchers trying to operationalize meditation in the context of comparative research. (PsycINFO Database Record (c) 2009 APA, all rights reserved). (from the journal abstract)

  • Defining a complex intervention: The development of demarcation criteria for “meditation”.

    Type Journal Article
    Author Kenneth Bond
    Author Maria B. Ospina
    Author Nicola Hooton
    Author Liza Bialy
    Author Donna M. Dryden
    Author Nina Buscemi
    Author David Shannahoff-Khalsa
    Author Jeffrey Dusek
    Author Linda E. Carlson
    Abstract The authors used a 5-round Delphi study with a panel of 7 experts in meditation research to achieve agreement on a set of criteria for a working definition of “meditation” for use in a comprehensive systematic review of the therapeutic use of meditation. Participants agreed that essential to a meditation practice is its use of (a) a defined technique, (b) logic relaxation, and (c) a self-induced state. Participants also agreed that a meditation practice may (d) involve a state of psychophysical relaxation somewhere in the process; (e) use a self-focus skill or anchor; (f) involve an altered state/mode of consciousness, mystic experience, enlightenment or suspension of logical thought processes; (g) be embedded in a religious/spiritual/philosophical context; or (h) involve an experience of mental silence. The results of this study provide insight into the challenges faced by researchers who want to demarcate meditative practices from nonmeditative practices, and they describe an approach to this problem that may prove useful for researchers trying to operationalize meditation in the context of comparative research. (PsycINFO Database Record (c) 2009 APA, all rights reserved). (from the journal abstract)
    Publication Psychology of Religion and Spirituality
    Volume 1
    Issue 2
    Pages 129-137
    Date May 2009
    DOI 10.1037/a0015736
    ISSN 1941-1022
    Short Title Defining a complex intervention
    URL http://search.ebscohost.com.ezproxy.bu.edu/login.aspx?
    direct=true&db=pdh&AN=rel-1-2-129&…
    Accessed Sat Sep 12 18:48:12 2009
    Library Catalog EBSCOhost
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • CAM
    • characteristics
    • Dualism
    • Meditation
    • mind–body techniques
    • Relaxation
    • yoga
  • The Mindfulness Revolution: Leading Psychologists, Scientists, Artists, and Meditatiion Teachers on the Power of Mindfulness in Daily Life

    Type Book
    Author Barry Boyce
    Author Jon Kabat-Zinn
    Author Daniel Siegel
    Author Thich Nhat Hanh
    Author Jack Kornfield
    Edition 1
    Publisher Shambhala
    Date 2011-03-08
    ISBN 1590308891
    Short Title The Mindfulness Revolution
    Library Catalog Amazon.com
    Date Added Thu Sep 29 08:56:31 2011
    Modified Thu Sep 29 08:56:31 2011
  • New beginnings: evidence that the meditational regimen can lead to optimization of perception, attention, cognition, and other functions

    Type Journal Article
    Author William C Bushell
    Abstract A "framework" is presented for understanding empirically confirmed and unconfirmed phenomena in the Indo-Tibetan meditation system, from an integrative perspective, and providing evidence that certain meditative practices enable meditators to realize the innate human potential to perceive light "at the limits imposed by quantum mechanics," on the level of individual photons. This is part of a larger Buddhist agenda to meditatitively develop perceptual/attentional capacities to achieve penetrating insight into the nature of phenomena. Such capacities may also allow advanced meditators to perceive changes in natural scenes that are "hidden" from persons with "normal" attentional capacities, according to research on "change blindness," and to enhance their visual system functioning akin to high-speed and time-lapse photography, in toto allowing for the perception, as well as sophisticated understanding, of the "moment to moment change or impermanence" universally characteristic of the phenomenal world but normally outside untrained attention and perception according to Buddhist doctrine.
    Publication Annals of the New York Academy of Sciences
    Volume 1172
    Pages 348-361
    Date Aug 2009
    Journal Abbr Ann. N. Y. Acad. Sci
    DOI 10.1111/j.1749-6632.2009.04960.x
    ISSN 1749-6632
    Short Title New beginnings
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19735255
    Accessed Sat Sep 26 15:11:20 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19735255
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Algorithms
    • Attention
    • Buddhism
    • Cognition
    • Consciousness
    • Humans
    • Meditation
    • Perception
    • Visual Perception

    Notes:

    • A “framework” is presented for understanding empirically confirmed and unconfirmed phenomena in the Indo-Tibetan meditation system, from an integrative perspective, and providing evidence that certain meditative practices enable meditators to realize the innate human potential to perceive light “at the limits imposed by quantum mechanics,” on the level of individual photons. This is part of a larger Buddhist agenda to meditatitively develop perceptual/attentional capacities to achieve penetrating insight into the nature of phenomena. Such capacities may also allow advanced meditators to perceive changes in natural scenes that are “hidden” from persons with “normal” attentional capacities, according to research on “change blindness,” and to enhance their visual system functioning akin to high-speed and time-lapse photography, in toto allowing for the perception, as well as sophisticated understanding, of the “moment to moment change or impermanence” universally characteristic of the phenomenal world but normally outside untrained attention and perception according to Buddhist doctrine.

  • Meditation in health: an operational definition

    Type Journal Article
    Author Roberto Cardoso
    Author Eduardo de Souza
    Author Luiz Camano
    Author José Roberto Leite
    Abstract Despite its evergrowing use in health-related areas, procedures characterized as meditation have been little or not at all defined operationally, which hinders its use in a standardized manner. In the present study, the authors present a possible operational definition of meditation, which has been used in social and academic projects, developed in Universidade Federal de São Paulo. In this proposal, it is emphasized that, in order to be characterized as meditation, the procedure should encompass the following requirements: (1) the use of a specific technique (clearly defined), (2) muscle relaxation in some moment of the process and (3) "logic relaxation"; (4) it must necessarily be a self-induced state, and (5) use of "self-focus" skill (coined "anchor").
    Publication Brain Research Protocols
    Volume 14
    Issue 1
    Pages 58-60
    Date November 2004
    Journal Abbr Brain Res Protoc
    DOI 10.1016/j.brainresprot.2004.09.002
    ISSN 1385-299X
    Short Title Meditation in health
    URL http://www.sciencedirect.com/science/article/B6T3N-4DKD49T-1/2/572fd518abb03915019c37a5a1ab20a8
    Accessed Tue Sep 1 21:50:59 2009
    Library Catalog ScienceDirect
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Definition
    • Health
    • Meditation

    Notes:

    • Despite its evergrowing use in health-related areas, procedures characterized as meditation have been little or not at all defined operationally, which hinders its use in a standardized manner. In the present study, the authors present a possible operational definition of meditation, which has been used in social and academic projects, developed in Universidade Federal de São Paulo. In this proposal, it is emphasized that, in order to be characterized as meditation, the procedure should encompass the following requirements: (1) the use of a specific technique (clearly defined), (2) muscle relaxation in some moment of the process and (3) “logic relaxation”; (4) it must necessarily be a self-induced state, and (5) use of “self-focus” skill (coined “anchor”).

  • An empirical study of the mechanisms of mindfulness in a mindfulness-based stress reduction program

    Type Journal Article
    Author James Carmody
    Author Ruth A Baer
    Author Emily L B Lykins
    Author Nicholas Olendzki
    Abstract S. L. Shapiro and colleagues (2006) have described a testable theory of the mechanisms of mindfulness and how it affects positive change. They describe a model in which mindfulness training leads to a fundamental change in relationship to experience (reperceiving), which leads to changes in self-regulation, values clarification, cognitive and behavioral flexibility, and exposure. These four variables, in turn, result in salutogenic outcomes. Analyses of responses from participants in a mindfulness-based stress-reduction program did not support the mediating effect of changes in reperceiving on the relationship of mindfulness with those four variables. However, when mindfulness and reperceiving scores were combined, partial support was found for the mediating effect of the four variables on measures of psychological distress. Issues arising in attempts to test the proposed theory are discussed, including the description of the model variables and the challenges to their assessment.
    Publication Journal of Clinical Psychology
    Volume 65
    Issue 6
    Pages 613-626
    Date Jun 2009
    Journal Abbr J Clin Psychol
    DOI 10.1002/jclp.20579
    ISSN 1097-4679
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19267330
    Accessed Sat Sep 26 15:17:34 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19267330
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adult
    • Aged
    • Attention
    • Awareness
    • Female
    • Humans
    • Male
    • Meditation
    • Middle Aged
    • Models, Psychological
    • Questionnaires
    • Relaxation Therapy
    • Social Control, Informal
    • Social Values
    • Stress, Psychological
    • Young Adult

    Notes:

    • S. L. Shapiro and colleagues (2006) have described a testable theory of the mechanisms of mindfulness and how it affects positive change. They describe a model in which mindfulness training leads to a fundamental change in relationship to experience (reperceiving), which leads to changes in self-regulation, values clarification, cognitive and behavioral flexibility, and exposure. These four variables, in turn, result in salutogenic outcomes. Analyses of responses from participants in a mindfulness-based stress-reduction program did not support the mediating effect of changes in reperceiving on the relationship of mindfulness with those four variables. However, when mindfulness and reperceiving scores were combined, partial support was found for the mediating effect of the four variables on measures of psychological distress. Issues arising in attempts to test the proposed theory are discussed, including the description of the model variables and the challenges to their assessment.

  • Loving-kindness meditation for chronic low back pain: results from a pilot trial

    Type Journal Article
    Author James W Carson
    Author Francis J Keefe
    Author Thomas R Lynch
    Author Kimberly M Carson
    Author Veeraindar Goli
    Author Anne Marie Fras
    Author Steven R Thorp
    Abstract PURPOSE: Loving-kindness meditation has been used for centuries in the Buddhist tradition to develop love and transform anger into compassion. This pilot study tested an 8-week loving-kindness program for chronic low back pain patients. METHOD: Patients (N = 43) were randomly assigned to the intervention or standard care. Standardized measures assessed patients' pain, anger, and psychological distress. FINDINGS: Post and follow-up analyses showed significant improvements in pain and psychological distress in the loving-kindness group, but no changes in the usual care group. Multilevel analyses of daily data showed that more loving-kindness practice on a given day was related to lower pain that day and lower anger the next day. CONCLUSIONS: Preliminary results suggest that the loving-kindness program can be beneficial in reducing pain, anger, and psychological distress in patients with persistent low back pain. IMPLICATIONS: Clinicians may find loving-kindness meditation helpful in the treatment of patients with persistent pain.
    Publication Journal of Holistic Nursing: Official Journal of the American Holistic Nurses' Association
    Volume 23
    Issue 3
    Pages 287-304
    Date Sep 2005
    Journal Abbr J Holist Nurs
    DOI 10.1177/0898010105277651
    ISSN 0898-0101
    Short Title Loving-kindness meditation for chronic low back pain
    URL http://www.ncbi.nlm.nih.gov/pubmed/16049118
    Accessed Fri Nov 13 15:19:40 2009
    Library Catalog NCBI PubMed
    Extra PMID: 16049118
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adaptation, Psychological
    • Adult
    • Aged
    • Aged, 80 and over
    • Anger
    • Attitude to Health
    • Holistic Nursing
    • Humans
    • Low Back Pain
    • Meditation
    • Middle Aged
    • Pain Measurement
    • Pilot Projects
    • Questionnaires
    • spirituality
    • Time Factors

    Notes:

    • Purpose: Loving-kindness meditation has been used for centuries in the Buddhist tradition to develop love and transform anger into compassion. This pilot study tested an 8-week loving-kindness program for chronic low back pain patients. Method: Patients (N = 43) were randomly assigned to the intervention or standard care. Standardized measures assessed patients’ pain, anger, and psychological distress. Findings: Post and follow-up analyses showed significant improvements in pain and psychological distress in the loving-kindness group, but no changes in the usual care group. Multilevel analyses of daily data showed that more loving-kindness practice on a given day was related to lower pain that day and lower anger the next day. Conclusions: Preliminary results suggest that the loving-kindness program can be beneficial in reducing pain, anger, and psychological distress in patients with persistent low back pain. Implications: Clinicians may find loving-kindness meditation helpful in the treatment of patients with persistent pain.

  • Cerebral blood flow effects of yoga training: preliminary evaluation of 4 cases

    Type Journal Article
    Author Debbie L Cohen
    Author Nancy Wintering
    Author Victoria Tolles
    Author Raymond R Townsend
    Author John T Farrar
    Author Mary Lou Galantino
    Author Andrew B Newberg
    Abstract OBJECTIVES: Experienced practitioners of yoga have been shown to alter brain function, but this case series measured cerebral blood flow before and after a 12-week training program in Iyengar yoga (IY) for naïve subjects. METHODS: On the first day, each of the 4 subjects listened to the teacher speaking on the history and background of the yoga program while they were injected with 250 MBq of (99m)Tc-bicisate and received a single photon emission computed tomography scan (pre-program baseline). Subjects then had their first IY training and were injected and scanned with 925 MBq bicisate while they did their first meditation (pre-program meditation). Subjects then underwent a 12-week training program in IY and then underwent the same imaging protocol with a postprogram baseline and postprogram meditation scan. Baseline and meditation scans, before and after training, were compared using paired t tests. RESULTS: There were significant decreases (p < 0.05) between the pre- and postprogram baseline scans in the right amygdala, dorsal medial cortex, and sensorimotor area. There was a significant difference (p < 0.05) in the pre- and postprogram percentage change (i.e., activation) in the right dorsal medial frontal lobe, prefrontal cortex, and right sensorimotor cortex. CONCLUSIONS: These initial findings suggest the brain experiences a "training effect" after 12 weeks of IY training.
    Publication Journal of Alternative and Complementary Medicine (New York, N.Y.)
    Volume 15
    Issue 1
    Pages 9-14
    Date Jan 2009
    Journal Abbr J Altern Complement Med
    DOI 10.1089/acm.2008.0008
    ISSN 1557-7708
    Short Title Cerebral blood flow effects of yoga training
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19769471
    Accessed Sat Sep 26 16:27:26 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19769471
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Objectives Experienced practitioners of yoga have been shown to alter brain function, but this case series measured cerebral blood flow before and after a 12-week training program in Iyengar yoga (IY) for naïve subjects. Methods: On the first day, each of the 4 subjects listened to the teacher speaking on the history and background of the yoga program while they were injected with 250 MBq of (99m)Tc-bicisate and received a single photon emission computed tomography scan (pre-program baseline). Subjects then had their first IY training and were injected and scanned with 925 MBq bicisate while they did their first meditation (pre-program meditation). Subjects then underwent a 12-week training program in IY and then underwent the same imaging protocol with a postprogram baseline and postprogram meditation scan. Baseline and meditation scans, before and after training, were compared using paired t tests. Results: There were significant decreases (p < 0.05) between the pre- and postprogram baseline scans in the right amygdala, dorsal medial cortex, and sensorimotor area. There was a significant difference (p < 0.05) in the pre- and postprogram percentage change (i.e., activation) in the right dorsal medial frontal lobe, prefrontal cortex, and right sensorimotor cortex. Conclusions: These initial findings suggest the brain experiences a “training effect” after 12 weeks of IY training.

  • Mindfulness-specific or generic mechanisms of action

    Type Journal Article
    Author Carlo C. DiClemente
    Abstract In this article, the author discusses the study which examines the effectiveness of transcendental meditation mindfulness training to treat patients with behavioral and emotional problems. It states that rumination and stress management are the key factors that help depression people and substance abuse disorders to respond brain activation using generic self-regulatory operations. Moreover, neurologists explained that approach would lower pain sensitivity in the brain.
    Publication Addiction
    Volume 105
    Issue 10
    Pages 1707-1708
    Date October 2010
    DOI 10.1111/j.1360-0443.2010.03013.x
    ISSN 09652140
    Date Added Thu Sep 29 08:59:59 2011
    Modified Thu Sep 29 08:59:59 2011

    Tags:

    • DEPRESSED persons
    • NEUROLOGISTS
    • PAIN -- Treatment
    • rumination
    • stress management
    • SUBSTANCE abuse
    • Transcendental Meditation
  • Can meditation slow rate of cellular aging? Cognitive stress, mindfulness, and telomeres

    Type Journal Article
    Author Elissa Epel
    Author Jennifer Daubenmier
    Author Judith Tedlie Moskowitz
    Author Susan Folkman
    Author Elizabeth Blackburn
    Abstract Understanding the malleable determinants of cellular aging is critical to understanding human longevity. Telomeres may provide a pathway for exploring this question. Telomeres are the protective caps at the ends of chromosomes. The length of telomeres offers insight into mitotic cell and possibly organismal longevity. Telomere length has now been linked to chronic stress exposure and depression. This raises the question of mechanism: How might cellular aging be modulated by psychological functioning? We consider two psychological processes or states that are in opposition to one another-threat cognition and mindfulness-and their effects on cellular aging. Psychological stress cognitions, particularly appraisals of threat and ruminative thoughts, can lead to prolonged states of reactivity. In contrast, mindfulness meditation techniques appear to shift cognitive appraisals from threat to challenge, decrease ruminative thought, and reduce stress arousal. Mindfulness may also directly increase positive arousal states. We review data linking telomere length to cognitive stress and stress arousal and present new data linking cognitive appraisal to telomere length. Given the pattern of associations revealed so far, we propose that some forms of meditation may have salutary effects on telomere length by reducing cognitive stress and stress arousal and increasing positive states of mind and hormonal factors that may promote telomere maintenance. Aspects of this model are currently being tested in ongoing trials of mindfulness meditation.
    Publication Annals of the New York Academy of Sciences
    Volume 1172
    Pages 34-53
    Date Aug 2009
    Journal Abbr Ann. N. Y. Acad. Sci
    DOI 10.1111/j.1749-6632.2009.04414.x
    ISSN 1749-6632
    Short Title Can meditation slow rate of cellular aging?
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19735238
    Accessed Sat Sep 26 15:11:55 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19735238
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adaptation, Psychological
    • Cell Aging
    • Cognition
    • Humans
    • Meditation
    • Stress, Psychological
    • Telomere

    Notes:

    • Understanding the malleable determinants of cellular aging is critical to understanding human longevity. Telomeres may provide a pathway for exploring this question. Telomeres are the protective caps at the ends of chromosomes. The length of telomeres offers insight into mitotic cell and possibly organismal longevity. Telomere length has now been linked to chronic stress exposure and depression. This raises the question of mechanism: How might cellular aging be modulated by psychological functioning? We consider two psychological processes or states that are in opposition to one another-threat cognition and mindfulness-and their effects on cellular aging. Psychological stress cognitions, particularly appraisals of threat and ruminative thoughts, can lead to prolonged states of reactivity. In contrast, mindfulness meditation techniques appear to shift cognitive appraisals from threat to challenge, decrease ruminative thought, and reduce stress arousal. Mindfulness may also directly increase positive arousal states. We review data linking telomere length to cognitive stress and stress arousal and present new data linking cognitive appraisal to telomere length. Given the pattern of associations revealed so far, we propose that some forms of meditation may have salutary effects on telomere length by reducing cognitive stress and stress arousal and increasing positive states of mind and hormonal factors that may promote telomere maintenance. Aspects of this model are currently being tested in ongoing trials of mindfulness meditation.

  • The Psychology Of Mindfulness: An Integrated Approach

    Type Book
    Author Michael Eysenck
    Author James Walsh
    Author Jaroslav Gera
    Edition 1
    Publisher Routledge
    Date 2011-03-15
    ISBN 0415414326
    Short Title The Psychology Of Mindfulness
    Library Catalog Amazon.com
    Date Added Thu Sep 29 08:56:31 2011
    Modified Thu Sep 29 08:56:31 2011
  • Envisioning a Future Contemplative Science of Mindfulness: Fruitful Methods and New Content for the Next Wave of Research

    Type Journal Article
    Author Eric Garland
    Author Susan Gaylord
    Abstract Mindfulness is an ancient spiritual practice as well as a unique behavioral technique involving the cultivation of non-judgmental, non-reactive, metacognitive awareness of present-moment experience. Given the growing interest in mindfulness across numerous academic and clinical disciplines, an agenda is needed to guide the next wave of research. Here, we suggest four areas that, in our view, are important for a future contemplative science of mindfulness: performance-based measures of mindfulness, scientific evaluation of Buddhist claims, neurophenomenology of mindfulness, and measuring changes in mindfulness-induced gene expression. By exploring these domains, the wisdom of the meditative traditions may be complemented by leading-edge empirical research methodologies.
    Publication Complementary Health Practice Review
    Volume 14
    Issue 1
    Pages 3-9
    Date Jan 2009
    Journal Abbr Complement Health Pract Rev
    DOI 10.1177/1533210109333718
    ISSN 1533-2101
    Short Title Envisioning a Future Contemplative Science of Mindfulness
    URL http://www.ncbi.nlm.nih.gov/pubmed/20671798
    Accessed Mon Mar 28 18:13:46 2011
    Library Catalog NCBI PubMed
    Extra PMID: 20671798
    Date Added Thu Sep 29 09:07:00 2011
    Modified Thu Sep 29 09:07:00 2011
  • The role of mindfulness in positive reappraisal

    Type Journal Article
    Author Eric Garland
    Author Susan Gaylord
    Author Jongbae Park
    Abstract Mindfulness meditation is increasingly well known for therapeutic efficacy in a variety of illnesses and conditions, but its mechanism of action is still under debate in scientific circles. In this paper, we propose a hypothetical causal model that argues for the role of mindfulness in positive reappraisal coping. Positive reappraisal is a critical component of meaning-based coping that enables individuals to adapt successfully to stressful life events. Mindfulness, as a metacognitive form of awareness, involves the process of decentering, a shifting of cognitive sets that enables alternate appraisals of life events. We review the concept of positive reappraisal in transactional stress and coping theory, then describe research and traditional literature related to mindfulness and positive reappraisal, and detail the central role of mindfulness in the reappraisal process. With this understanding, we present a causal model explicating the proposed mechanism. The discussion has implications for clinical practice, suggesting how mindfulness-based integrative medicine interventions can be designed to support adaptive coping processes.
    Publication Explore (New York, N.Y.)
    Volume 5
    Issue 1
    Pages 37-44
    Date 2009 Jan-Feb
    Journal Abbr Explore (NY)
    DOI 10.1016/j.explore.2008.10.001
    ISSN 1550-8307
    URL http://www.ncbi.nlm.nih.gov/pubmed/19114262
    Accessed Mon Mar 28 18:18:24 2011
    Library Catalog NCBI PubMed
    Extra PMID: 19114262
    Date Added Thu Sep 29 09:07:00 2011
    Modified Thu Sep 29 09:07:00 2011

    Tags:

    • Cognitive Therapy
    • Humans
    • Internal-External Control
    • Meditation
    • Mind-Body Relations, Metaphysical
    • Models, Psychological
    • Psychotherapy, Group
    • Quality of Life
  • The value of mindfulness-based methods in teaching at a clinical field placement

    Type Journal Article
    Author Nurper Gökhan
    Author Edward F. Meehan
    Author Kevin Peters
    Publication Psychological Reports
    Volume 106
    Issue 2
    Pages 455-466
    Date 2010
    Journal Abbr PR
    DOI 10.2466/PR0.106.2.455-466
    ISSN 0033-2941
    URL http://asp.ammonsscientific.com/find.php?
    resource=PR0.106.2.455
    Date Added Thu Sep 29 09:04:35 2011
    Modified Thu Sep 29 09:04:35 2011
  • Intensive meditation training, immune cell telomerase activity, and psychological mediators.

    Type Journal Article
    Author Tonya L. Jacobs
    Author Elissa S. Epel
    Author Jue Lin
    Author Elizabeth H. Blackburn
    Author Owen M. Wolkowitz
    Author David A. Bridwell
    Author Anthony P. Zanesco
    Author Stephen R. Aichele
    Author Baljinder K. Sahdra
    Author Katherine A. MacLean
    Author Brandon G. King
    Author Phillip R. Shaver
    Author Erika L. Rosenberg
    Author Emilio Ferrer
    Author B. Alan Wallace
    Author Clifford D. Saron
    Abstract Background: Telomerase activity is a predictor of long-term cellular viability, which decreases with chronic psychological distress (Epel et al., 2004). Buddhist traditions claim that meditation decreases psychological distress and promotes well-being (e.g., Dalai Lama and Cutler, 2009). Therefore, we investigated the effects of a 3-month meditation retreat on telomerase activity and two major contributors to the experience of stress: Perceived Control (associated with decreased stress) and Neuroticism (associated with increased subjective distress). We used mediation models to test whether changes in Perceived Control and Neuroticism explained meditation retreat effects on telomerase activity. In addition, we investigated whether two qualities developed by meditative practice, increased Mindfulness and Purpose in Life, accounted for retreat-related changes in the two stress-related variables and in telomerase activity. Methods: Retreat participants (n = 30) meditated for ∼6h daily for 3 months and were compared with a wait-list control group (n = 30) matched for age, sex, body mass index, and prior meditation experience. Retreat participants received instruction in concentrative meditation techniques and complementary practices used to cultivate benevolent states of mind (Wallace, 2006). Psychological measures were assessed pre- and post-retreat. Peripheral blood mononuclear cell samples were collected post-retreat for telomerase activity. Because there were clear, a priori hypotheses, 1-tailed significance criteria were used throughout. Results: Telomerase activity was significantly greater in retreat participants than in controls at the end of the retreat (p < 0.05). Increases in Perceived Control, decreases in Neuroticism, and increases in both Mindfulness and Purpose in Life were greater in the retreat group (p < 0.01). Mediation analyses indicated that the effect of the retreat on telomerase was mediated by increased Perceived Control and decreased Neuroticism. In turn, changes in Perceived Control and Neuroticism were both partially mediated by increased Mindfulness and Purpose in Life. Additionally, increases in Purpose in Life directly mediated the telomerase group difference, whereas increases in Mindfulness did not. Conclusions: This is the first study to link meditation and positive psychological change with telomerase activity. Although we did not measure baseline telomerase activity, the data suggest that increases in perceived control and decreases in negative affectivity contributed to an increase in telomerase activity, with implications for telomere length and immune cell longevity. Further, Purpose in Life is influenced by meditative practice and directly affects both perceived control and negative emotionality, affecting telomerase activity directly as well as indirectly. (PsycINFO Database Record (c) 2011 APA, all rights reserved) (journal abstract)
    Publication Psychoneuroendocrinology
    Volume 36
    Issue 5
    Pages 664-681
    Date June 2011
    DOI 10.1016/j.psyneuen.2010.09.010
    ISSN 0306-4530
    Library Catalog EBSCOhost
    Date Added Thu Sep 29 08:54:25 2011
    Modified Thu Sep 29 08:54:25 2011

    Tags:

    • Distress
    • immune cell telomerase activities
    • intensive meditation training
    • Meditation
    • Mindfulness
    • Psychological distress
    • psychological mediators
  • Meditative prayer, hope, adult attachment, and forgiveness: A proposed model.

    Type Journal Article
    Author Peter J. Jankowski
    Author Steven J. Sandage
    Abstract The present study tested a theoretical model of the relationship between meditative prayer and interpersonal forgiveness with hope and adult attachment as mediator variables. Results supported the proposed multiple mediation model as determined by multiple measures of model fit with the data. Significant direct effects were observed between meditative prayer and hope, hope and adult attachment, and adult attachment and forgiveness. A significant total indirect effect was found between meditative prayer and forgiveness. A significant specific indirect effect was also observed between meditative prayer and adult attachment with hope as the mediator, and between hope and forgiveness with adult attachment as a mediator. The concept of affect regulation is proposed as a possible unifying mechanism of the variables in the proposed model and implications are discussed in terms of existing literature and promoting interpersonal forgiveness in counseling. (PsycINFO Database Record (c) 2011 APA, all rights reserved). (from the journal abstract)
    Publication Psychology of Religion and Spirituality
    Volume 3
    Issue 2
    Pages 115-131
    Date May 2011
    DOI 10.1037/a0021601
    ISSN 1941-1022
    Short Title Meditative prayer, hope, adult attachment, and forgiveness
    Library Catalog EBSCOhost
    Date Added Thu Sep 29 08:55:16 2011
    Modified Thu Sep 29 08:55:16 2011

    Tags:

    • adult attachment
    • attachment behavior
    • dispositional forgiveness
    • Forgiveness
    • hope
    • Interpersonal Relationships
    • meditative prayer
    • prayer
    • relational spirituality
    • religion
    • spirituality
  • Potential role of self-induced EEG fast oscillations in predisposition to seizures in meditators

    Type Journal Article
    Author Harinder Jaseja
    Abstract Meditation is a mental exercise practiced widely as an antistress measure and in the belief that it possesses remedial efficacy for a number of medical ailments, especially neurological disorders. Further, there is a general belief that meditation is an absolutely safe practice devoid of any harmful effects. However, with the advent of neuroimaging techniques, the possibility of adverse effects has been raised in recent times. One such issue that has been debated is the potential epileptogenic versus antiepileptic influence exerted by meditation. This brief article attempts to study the potential role of meditation-induced EEG fast oscillations in the predisposition to seizures in meditation practitioners with epilepsy.
    Publication Epilepsy & Behavior
    Volume 17
    Issue 1
    Pages 124-125
    Date January 2010
    DOI 10.1016/j.yebeh.2009.10.022
    ISSN 1525-5050
    Accessed Fri Jan 29 12:39:37 2010
    Library Catalog ScienceDirect
    Date Added Thu Sep 29 09:04:02 2011
    Modified Thu Sep 29 09:04:02 2011

    Tags:

    • EEG
    • Fast oscillations
    • Gamma activity
    • Meditation
  • Effects of Meditation Training on Attentional Networks: A Randomized Controlled Trial Examining Psychometric and Electrophysiological (EEG) Measures

    Type Thesis
    Author A. A Joshi
    University University of Oregon
    Date 2007
    Short Title Effects of Meditation Training on Attentional Networks
    Library Catalog Google Scholar
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011
  • Developing an observing attitude: an analysis of meditation diaries in an MBSR clinical trial

    Type Journal Article
    Author Catherine E Kerr
    Author Krishnapriya Josyula
    Author Ronnie Littenberg
    Abstract Mindfulness-based stress reduction (MBSR) is an 8-week training that is designed to teach participants mindful awareness of the present moment. In randomized clinical trials (RCTs), MBSR has demonstrated efficacy in various conditions including reducing chronic pain-related distress and improving quality of life in healthy individuals. There have, however, been no qualitative studies investigating participants' descriptions of changes experienced over multiple time points during the course of the programme. This qualitative study of an MBSR cohort (N = 8 healthy individuals) in a larger RCT examined participants' daily diary descriptions of their home-practice experiences. The study used a two-part method, combining grounded theory with a close-ended coding approach. The grounded theory analysis revealed that during the trial, all participants, to varying degrees, described moments of distress related to practice; at the end of the course, all participants who completed the training demonstrated greater detail and clarity in their descriptions, improved affect, and the emergence of an observing self. The closed-ended coding schema, carried out to shed light on the development of an observing self, revealed that the emergence of an observing self was not related to the valence of participants' experiential descriptions: even participants whose diaries contained predominantly negative characterizations of their experience throughout the trial were able, by the end of the trial, to demonstrate an observing, witnessing attitude towards their own distress. Progress in MBSR may rely less on the valence of participants' experiences and more on the way participants describe and relate to their own inner experience.
    Publication Clinical Psychology & Psychotherapy
    Volume 18
    Issue 1
    Pages 80-93
    Date Jan 2011
    Journal Abbr Clin Psychol Psychother
    DOI 10.1002/cpp.700
    ISSN 1099-0879
    Short Title Developing an observing attitude
    Accessed Sun Feb 13 10:34:23 2011
    Library Catalog NCBI PubMed
    Extra PMID: 21226129
    Date Added Thu Sep 29 08:57:52 2011
    Modified Thu Sep 29 08:57:52 2011
  • Effects of low-dose mindfulness-based stress reduction (MBSR-ld) on working adults

    Type Journal Article
    Author Maryanna D Klatt
    Author Janet Buckworth
    Author William B Malarkey
    Abstract Mindfulness-based stress reduction (MBSR) has produced behavioral, psychological, and physiological benefits, but these programs typically require a substantial time commitment from the participants. This study assessed the effects of a shortened (low-dose [ld]) work-site MBSR intervention (MBSR-ld) on indicators of stress in healthy working adults to determine if results similar to those obtained in traditional MBSR could be demonstrated. Participants were randomized into MBSR-ld and wait-list control groups. Self-reported perceived stress, sleep quality, and mindfulness were measured at the beginning and end of the 6-week intervention. Salivary cortisol was assessed weekly. Significant reductions in perceived stress (p = .0025) and increases in mindfulness (p = .0149) were obtained for only the MBSR-ld group (n = 22). Scores on the global measure of sleep improved for the MBSR-ld group (p = .0018) as well as for the control group (p = .0072; n = 20). Implications and future research are discussed.
    Publication Health Education & Behavior: The Official Publication of the Society for Public Health Education
    Volume 36
    Issue 3
    Pages 601-614
    Date Jun 2009
    Journal Abbr Health Educ Behav
    DOI 10.1177/1090198108317627
    ISSN 1090-1981
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/18469160
    Accessed Sat Sep 26 15:16:42 2009
    Library Catalog NCBI PubMed
    Extra PMID: 18469160
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adolescent
    • Adult
    • Female
    • Humans
    • Hydrocortisone
    • Male
    • Meditation
    • Middle Aged
    • Occupational Exposure
    • Saliva
    • Stress, Psychological
    • Treatment Outcome
    • Young Adult

    Notes:

    • Mindfulness-based stress reduction (MBSR) has produced behavioral, psychological, and physiological benefits, but these programs typically require a substantial time commitment from the participants. This study assessed the effects of a shortened (low-dose [ld]) work-site MBSR intervention (MBSR-ld) on indicators of stress in healthy working adults to determine if results similar to those obtained in traditional MBSR could be demonstrated. Participants were randomized into MBSR-ld and wait-list control groups. Self-reported perceived stress, sleep quality, and mindfulness were measured at the beginning and end of the 6-week intervention. Salivary cortisol was assessed weekly. Significant reductions in perceived stress (p = .0025) and increases in mindfulness (p = .0149) were obtained for only the MBSR-ld group (n = 22). Scores on the global measure of sleep improved for the MBSR-ld group (p = .0018) as well as for the control group (p = .0072; n = 20). Implications and future research are discussed.

  • Brief meditation training can improve perceived stress and negative mood.

    Type Journal Article
    Author James D. Lane
    Author Jon E. Seskevich
    Author Carl F. Pieper
    Abstract OBJECTIVES: To test a brief, non-sectarian program of meditation training for effects on perceived stress and negative emotion, and to determine effects of practice frequency and test the moderating effects of neuroticism (emotional lability) on treatment outcome. DESIGN AND SETTING: The study used a single-group, open-label, pre-test post-test design conducted in the setting of a university medical center. PARTICIPANTS: Healthy adults (N=200) interested in learning meditation for stress-reduction were enrolled. One hundred thirty-three (76% females) completed at least 1 follow-up visit and were included in data analyses. INTERVENTION: Participants learned a simple mantra-based meditation technique in 4, 1-hour small-group meetings, with instructions to practice for 15-20 minutes twice daily. Instruction was based on a psychophysiological model of meditation practice and its expected effects on stress. OUTCOME MEASURES: Baseline and monthly follow-up measures of Profile of Mood States; Perceived Stress Scale; State-Trait Anxiety Inventory (STAI); and Brief Symptom Inventory (BSI). Practice frequency was indexed by monthly retrospective ratings. Neuroticism was evaluated as a potential moderator of treatment effects. RESULTS: All 4 outcome measures improved significantly after instruction, with reductions from baseline that ranged from 14% (STAI) to 36% (BSI). More frequent practice was associated with better outcome. Higher baseline neuroticism scores were associated with greater improvement. CONCLUSIONS: Preliminary evidence suggests that even brief instruction in a simple meditation technique can improve negative mood and perceived stress in healthy adults, which could yield long-term health benefits. Frequency of practice does affect outcome. Those most likely to experience negative emotions may benefit the most from the intervention.
    Publication Alternative Therapies in Health and Medicine
    Volume 13
    Issue 1
    Pages 38-44
    Date 2007-01
    ISSN 1078-6791
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Objectives To test a brief, non-sectarian program of meditation training for effects on perceived stress and negative emotion, and to determine effects of practice frequency and test the moderating effects of neuroticism (emotional lability) on treatment outcome. DESIGN AND Setting: The study used a single-group, open-label, pre-test post-test design conducted in the setting of a university medical center. Patricipants: Healthy adults (N=200) interested in learning meditation for stress-reduction were enrolled. One hundred thirty-three (76% females) completed at least 1 follow-up visit and were included in data analyses. INTERVENTION: Participants learned a simple mantra-based meditation technique in 4, 1-hour small-group meetings, with instructions to practice for 15-20 minutes twice daily. Instruction was based on a psychophysiological model of meditation practice and its expected effects on stress. Outcome measures: Baseline and monthly follow-up measures of Profile of Mood States; Perceived Stress Scale; State-Trait Anxiety Inventory (STAI); and Brief Symptom Inventory (BSI). Practice frequency was indexed by monthly retrospective ratings. Neuroticism was evaluated as a potential moderator of treatment effects. Results: All 4 outcome measures improved significantly after instruction, with reductions from baseline that ranged from 14% (STAI) to 36% (BSI). More frequent practice was associated with better outcome. Higher baseline neuroticism scores were associated with greater improvement. Conclusions: Preliminary evidence suggests that even brief instruction in a simple meditation technique can improve negative mood and perceived stress in healthy adults, which could yield long-term health benefits. Frequency of practice does affect outcome. Those most likely to experience negative emotions may benefit the most from the intervention.

  • Meditative movement as a category of exercise: implications for research

    Type Journal Article
    Author Linda Larkey
    Author Roger Jahnke
    Author Jennifer Etnier
    Author Julie Gonzalez
    Abstract INTRODUCTION: Meditative Movement (MM) is proposed as a new category of exercise defined by (a) some form of movement or body positioning, (b) a focus on breathing, and (c) a cleared or calm state of mind with a goal of (d) deep states of relaxation. REVIEW: Two forms of exercise meeting this definition, Qigong and Tai Chi, are reviewed to examine health benefits found in the research literature, recap elements that should be assessed in MM research, and suggest where aspects of MM intersect with, and are distinguished from, conventional forms of exercise. RESULTS: Relevant dimensions of the key elements of MM, such as frequency, duration, type of movement, degree of exertion, description of breathing, and achievement of relaxed state are recommended to be clearly described and measured to consistently define the category across studies and clarify how MM may affect health outcomes in similar, and perhaps different, ways than conventional exercise. CONCLUSIONS: If these suggested standards are used, we will gain a better understanding of which elements are necessary for achieving targeted outcomes. Over time, as MM is studied as a category of exercise, research may progress more efficiently to define the domains of physiological and psychological benefit.
    Publication Journal of Physical Activity & Health
    Volume 6
    Issue 2
    Pages 230-238
    Date Mar 2009
    Journal Abbr J Phys Act Health
    ISSN 1543-3080
    Short Title Meditative movement as a category of exercise
    Accessed Tue Feb 22 19:12:08 2011
    Library Catalog NCBI PubMed
    Extra PMID: 19420401
    Date Added Thu Sep 29 09:07:00 2011
    Modified Thu Sep 29 09:07:00 2011

    Tags:

    • Biomedical Research
    • Blood Pressure
    • Breathing Exercises
    • Humans
    • Immune System
    • Meditation
    • mental health
    • Movement
    • Postural Balance
    • Relaxation
    • Stress, Psychological
    • Tai Ji
  • A quantitative electroencephalographic study of meditation and binaural beat entrainment

    Type Journal Article
    Author Christina F Lavallee
    Author Stanley A Koren
    Author Michael A Persinger
    Abstract Abstract Objectives: The study objective was to determine the quantitative electroencephalographic correlates of meditation, as well as the effects of hindering (15 Hz) and facilitative (7 Hz) binaural beats on the meditative process. Design: The study was a mixed design, with experience of the subject as the primary between-subject measure and power of the six classic frequency bands (δ, θ, low α, high α, β, γ), neocortical lobe (frontal, temporal, parietal, occipital), hemisphere (left, right), and condition (meditation only, meditation with 7-Hz beats, meditation with 15-Hz beats) as the within-subject measures. Location: The study was conducted at Laurentian University in Sudbury, Ontario, Canada. Subjects: The subjects comprised novice (mean of 8 months experience) and experienced (mean of 18 years experience) meditators recruited from local meditation groups. Intervention: Experimental manipulation included application of hindering and facilitative binaural beats to the meditative process. Results: Experienced meditators displayed increased left temporal lobe δ power when the facilitative binaural beats were applied, whereas the effect was not observed for the novice subjects in this condition. When the hindering binaural beats were introduced, the novice subjects consistently displayed more γ power than the experienced subjects over the course of their meditation, relative to baseline. Conclusions: Based on the results of this study, novice meditators were not able to maintain certain levels of θ power in the occipital regions when hindering binaural beats were presented, whereas when the facilitative binaural beats were presented, the experienced meditators displayed increased θ power in the left temporal lobe. These results suggest that the experienced meditators have developed techniques over the course of their meditation practice to counter hindering environmental stimuli, whereas the novice meditators have not yet developed those techniques.
    Publication Journal of Alternative and Complementary Medicine (New York, N.Y.)
    Volume 17
    Issue 4
    Pages 351-355
    Date Apr 2011
    Journal Abbr J Altern Complement Med
    DOI 10.1089/acm.2009.0691
    ISSN 1557-7708
    URL http://www.ncbi.nlm.nih.gov/pubmed/21480784
    Accessed Mon May 9 19:02:13 2011
    Library Catalog NCBI PubMed
    Extra PMID: 21480784
    Date Added Thu Sep 29 08:55:31 2011
    Modified Thu Sep 29 08:55:31 2011
  • Brain Functional Mapping on Physiological Regulating Phenomena during Meditation Exercise

    Type Journal Article
    Author C-H Liou
    Author C-H Hsieh
    Author C-W Hsieh
    Author C-H Wang
    Author S-C Lee
    Author J-H Chen
    Abstract Introduction The mechanism why meditation improves people's health remains unclear. Since different meditations may activate different regions in brain, we can use fMRI to investigate it. Chinese original quiet sitting (COQS) is mainly one kind of traditional Chinese meditation. It is composed of two different parts: a short period of keeping phrase and receiving cosmic Qi energy (named “Invitation of Primordial Qi”: IPQ), and a long period of relaxation with no further action (named “Allow its Natural Workings”: ANW). Chen had studied it by EEG [1]. We also had a previous study by fMRI [2-3]. In this paper, we want to study the brain activation area during the ANW state. Methods One special kind of paradigm was designed to find the BOLD signals during the ANW periods. It consisted of three parts: 3-minutes of control state, followed by 3-minutes of IPQ state, and then 9-minutes of ANW state. Total scan time was 15-minutes. Seventeen well-trained subjects with seven females and ten males participated in this fMRI study. Their mean age was 47.5 ± 2.9 (Mean ± SEM, 32not, vert, similar70) with meditation experience 12.4 ± 1.4 (4not, vert, similar21) years. Their regularly mean practice times every day was about 1.3 ± 0.1 (1not, vert, similar3) with mean practice duration 53.8 ± 5.5 (30not, vert, similar120) minutes each time. Experiments were performed on Bruker MEDSPEC 3T system (Bruker, Ettlingen, Germany). Images were acquired using gradient-echo EPI with matrix size 128×128, TE 35ms, and TR 6000ms. All experiments had 12 continuous slices (slice thickness=7mm), FOV 30×30cm2. Data were analyzed by random effect analysis in SPM. Results Our results showed that (with p<0.05, T>1.75, degree of freedom=16, and number of clusters>25), during the ANW period, certain brain regions showed negative activation, such as (showed in Talairach pick and T-value): dACC (dorsal anterior cingulate cortex, 4,42,12, T= −5.89), superior frontal gyrus (−22,44,22, T= −4.83), caudate body (−6,12,14, T= −2.60), amygdala (26,-12,-28, T= −5.07, −30,-8,-30, T= −4.69), superior temporal gyrus (68,-24,6, T= −4.10, −50,-42,6, T= −4.53) and cuneus (−22,-96,-2, T= −4.51). Other regions showed positive activation, such as: vACC (ventral anterior cingulate cortex, -6,22,-4, T=4.51), declive (−6,-56,-16, T=2.89), culmen (−6,-54,-16, T=2.74), thalamus (4,-8,10, T=2.57) and hypothalamus (−4,6,-24, T=2.38). Conclusions During the COQS-ANW state, the activity of cognition, self-awareness, sensation and the memory system of the body seemed all “calming down”. Lacking of the emotional event and the physical activity, amygdala might show negative activation. The more profound signification of all these negative activation regions still need further study. The positive activation regions showed special physiological meanings. Hypothalamus is a collecting center for information concerned with the internal well-being of the body. Much of this information is used to control secretions of the many globally important pituitary hormones [4]. VACC may involve in the regulation of mental and emotional activities. Thalamus may regulate the autonomic and visceral functions, motor systems and sensory systems. The activation of declive and culmen in cerebellum may be involved in the subtle regulation of motor functions.
    Publication NeuroImage
    Volume 47
    Issue Supplement 1
    Pages S156
    Date July 2009
    DOI 10.1016/S1053-8119(09)71628-3
    ISSN 1053-8119
    URL http://www.sciencedirect.com.ezproxy.bu.edu/science/article/B6WNP-4X3PHYG-224/2/25a156de836269f31795d1ce23d6c055
    Accessed Sat Sep 26 18:36:58 2009
    Library Catalog ScienceDirect
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Introduction: The mechanism why meditation improves people’s health remains unclear. Since different meditations may activate different regions in brain, we can use fMRI to investigate it. Chinese original quiet sitting (COQS) is mainly one kind of traditional Chinese meditation. It is composed of two different parts: a short period of keeping phrase and receiving cosmic Qi energy (named “Invitation of Primordial Qi”: IPQ), and a long period of relaxation with no further action (named “Allow its Natural Workings”: ANW). Chen had studied it by EEG [1]. We also had a previous study by fMRI [2-3]. In this paper, we want to study the brain activation area during the ANW state. Methods: One special kind of paradigm was designed to find the BOLD signals during the ANW periods. It consisted of three parts: 3-minutes of control state, followed by 3-minutes of IPQ state, and then 9-minutes of ANW state. Total scan time was 15-minutes. Seventeen well-trained subjects with seven females and ten males participated in this fMRI study. Their mean age was 47.5 ± 2.9 (Mean ± SEM, 32not, vert, similar70) with meditation experience 12.4 ± 1.4 (4not, vert, similar21) years. Their regularly mean practice times every day was about 1.3 ± 0.1 (1not, vert, similar3) with mean practice duration 53.8 ± 5.5 (30not, vert, similar120) minutes each time. Experiments were performed on Bruker MEDSPEC 3T system (Bruker, Ettlingen, Germany). Images were acquired using gradient-echo EPI with matrix size 128×128, TE 35ms, and TR 6000ms. All experiments had 12 continuous slices (slice thickness=7mm), FOV 30×30cm2. Data were analyzed by random effect analysis in SPM. Results: Our results showed that (with p<0.05, T>1.75, degree of freedom=16, and number of clusters>25), during the ANW period, certain brain regions showed negative activation, such as (showed in Talairach pick and T-value): dACC (dorsal anterior cingulate cortex, 4,42,12, T= −5.89), superior frontal gyrus (−22,44,22, T= −4.83), caudate body (−6,12,14, T= −2.60), amygdala (26,-12,-28, T= −5.07, −30,-8,-30, T= −4.69), superior temporal gyrus (68,-24,6, T= −4.10, −50,-42,6, T= −4.53) and cuneus (−22,-96,-2, T= −4.51). Other regions showed positive activation, such as: vACC (ventral anterior cingulate cortex, -6,22,-4, T=4.51), declive (−6,-56,-16, T=2.89), culmen (−6,-54,-16, T=2.74), thalamus (4,-8,10, T=2.57) and hypothalamus (−4,6,-24, T=2.38). Conclusions: During the COQS-ANW state, the activity of cognition, self-awareness, sensation and the memory system of the body seemed all “calming down”. Lacking of the emotional event and the physical activity, amygdala might show negative activation. The more profound signification of all these negative activation regions still need further study. The positive activation regions showed special physiological meanings. Hypothalamus is a collecting center for information concerned with the internal well-being of the body. Much of this information is used to control secretions of the many globally important pituitary hormones [4]. VACC may involve in the regulation of mental and emotional activities. Thalamus may regulate the autonomic and visceral functions, motor systems and sensory systems. The activation of declive and culmen in cerebellum may be involved in the subtle regulation of motor functions.

  • The mental self

    Type Book Section
    Author Hans C. Lou
    Author Markus Nowak
    Author Troels W. Kjaer
    Contributor Steven Laureys
    Abstract In meditation both the quality and the contents of consciousness may be voluntarily changed, making it an obvious target in the quest for the neural correlate of consciousness. Here we present the results of a positron emission tomography study of yoga nidra relaxation meditation when compared with the normal resting conscious state. Meditation is accompanied by a relatively increased perfusion in the sensory imagery system: hippocampus and sensory and higher order association regions, with decreased perfusion in the executive system: dorsolateral prefrontal cortex, anterior cingulate gyrus, striatum, thalamus, pons, and cerebellum. To identify regions active in both systems we performed a principal component analysis of the results. This separated the blood flow data into two groups of regions, explaining 25 and 18% of their variance: One group corresponded to the executive system, and the other to the systems supporting sensory imagery. A small group of regions contributed considerably to both networks: medial parietal and medial prefrontal cortices, together with the striatum. The inclusion of the striatum and our subsequent finding of increased striatal dopamine binding to D2 receptors during meditation suggested dopaminergic regulation of this circuit. We then investigated the neural networks supporting episodic retrieval of judgments of individuals with different degrees of self-relevance, in the decreasing order: self, best friend, and the Danish queen. We found that all conditions activated a medial prefrontal -- precuneus/posterior cingulate cortex, thalamus, and cerebellum. This activation occurred together with the activation of the left lateral prefrontal/temporal cortex. The latter was dependent on the requirement of retrieval of semantic information, being most pronounced in the "queen" condition. Transcranial magnetic stimulation, targeting precuneus, was then applied to the medial parietal region to transiently disrupt the normal function of the circuitry. We found a decreased efficiency of retrieval of self-judgment compared to the judgment of best friend. This shows that the integrity of the function of precuneus is essential for self-reference, but not for reference to others.
    Book Title The Boundaries of Consciousness: Neurobiology and Neuropathology
    Volume Volume 150
    Publisher Elsevier
    Date 2005
    Pages 197-204, 594
    ISBN 0079-6123
    URL http://www.sciencedirect.com/science/article/B7CV6-4H62GJY-P/2/5e96e377a6a4a212776dee0e64a7721b
    Accessed Tue Sep 1 21:55:35 2009
    Library Catalog ScienceDirect
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • In meditation both the quality and the contents of consciousness may be voluntarily changed, making it an obvious target in the quest for the neural correlate of consciousness. Here we present the results of a positron emission tomography study of yoga nidra relaxation meditation when compared with the normal resting conscious state. Meditation is accompanied by a relatively increased perfusion in the sensory imagery system: hippocampus and sensory and higher order association regions, with decreased perfusion in the executive system: dorsolateral prefrontal cortex, anterior cingulate gyrus, striatum, thalamus, pons, and cerebellum. To identify regions active in both systems we performed a principal component analysis of the results. This separated the blood flow data into two groups of regions, explaining 25 and 18% of their variance: One group corresponded to the executive system, and the other to the systems supporting sensory imagery. A small group of regions contributed considerably to both networks: medial parietal and medial prefrontal cortices, together with the striatum. The inclusion of the striatum and our subsequent finding of increased striatal dopamine binding to D2 receptors during meditation suggested dopaminergic regulation of this circuit. We then investigated the neural networks supporting episodic retrieval of judgments of individuals with different degrees of self-relevance, in the decreasing order: self, best friend, and the Danish queen. We found that all conditions activated a medial prefrontal -- precuneus/posterior cingulate cortex, thalamus, and cerebellum. This activation occurred together with the activation of the left lateral prefrontal/temporal cortex. The latter was dependent on the requirement of retrieval of semantic information, being most pronounced in the “queen” condition. Transcranial magnetic stimulation, targeting precuneus, was then applied to the medial parietal region to transiently disrupt the normal function of the circuitry. We found a decreased efficiency of retrieval of self-judgment compared to the judgment of best friend. This shows that the integrity of the function of precuneus is essential for self-reference, but not for reference to others.

  • Mindfulness meditation research: issues of participant screening, safety procedures, and researcher training

    Type Journal Article
    Author M Kathleen B Lustyk
    Author Neharika Chawla
    Author Roger S Nolan
    Author G Alan Marlatt
    Abstract Increasing interest in mindfulness meditation (MM) warrants discussion of research safety. Side effects of meditation with possible adverse reactions are reported in the literature. Yet participant screening procedures, research safety guidelines, and standards for researcher training have not been developed and disseminated in the MM field of study. The goal of this paper is to summarize safety concerns of MM practice and offer scholars some practical tools to use in their research. For example, we offer screener schematics aimed at determining the contraindication status of potential research participants. Moreover, we provide information on numerous MM training options. Ours is the first presentation of this type aimed at helping researchers think through the safety and training issues presented herein. Support for our recommendations comes from consulting 17 primary publications and 5 secondary reports/literature reviews of meditation side effects. Mental health consequences were the most frequently reported side effects, followed by physical health then spiritual health consequences. For each of these categories of potential adverse effects, we offer MM researchers methods to assess the relative risks of each as it pertains to their particular research programs.
    Publication Advances in Mind-Body Medicine
    Volume 24
    Issue 1
    Pages 20-30
    Date 2009
    Journal Abbr Adv Mind Body Med
    ISSN 1532-1843
    Short Title Mindfulness meditation research
    Accessed Tue Feb 22 19:29:57 2011
    Library Catalog NCBI PubMed
    Extra PMID: 20671334
    Date Added Thu Sep 29 09:07:00 2011
    Modified Thu Sep 29 09:07:00 2011

    Tags:

    • Attention
    • Biomedical Research
    • Humans
    • Meditation
    • Mental Disorders
    • mental health
    • Mind-Body Therapies
    • Patient Selection
    • Research Personnel
    • spirituality
  • BOLD signal in insula is differentially related to cardiac function during compassion meditation in experts vs. novices

    Type Journal Article
    Author Antoine Lutz
    Author Lawrence L Greischar
    Author David M Perlman
    Author Richard J Davidson
    Abstract The brain and the cardiovascular system influence each other during the processing of emotion. The study of the interactions of these systems during emotion regulation has been limited in human functional neuroimaging, despite its potential importance for physical health. We have previously reported that mental expertise in cultivation of compassion alters the activation of circuits linked with empathy and theory of mind in response to emotional stimuli. Guided by the finding that heart rate increases more during blocks of compassion meditation than neutral states, especially for experts, we examined the interaction between state (compassion vs. neutral) and group (novice, expert) on the relation between heart rate and BOLD signal during presentation of emotional sounds presented during each state. Our findings revealed that BOLD signal in the right middle insula showed a significant association with heart rate (HR) across state and group. This association was stronger in the left middle/posterior insula when experts were compared to novices. The positive coupling of HR and BOLD was higher within the compassion state than within the neutral state in the dorsal anterior cingulate cortex for both groups, underlining the role of this region in the modulation of bodily arousal states. This state effect was stronger for experts than novices in somatosensory cortices and the right inferior parietal lobule (group by state interaction). These data confirm that compassion enhances the emotional and somatosensory brain representations of others' emotions, and that this effect is modulated by expertise. Future studies are needed to further investigate the impact of compassion training on these circuits.
    Publication NeuroImage
    Volume 47
    Issue 3
    Pages 1038-1046
    Date Sep 2009
    Journal Abbr Neuroimage
    DOI 10.1016/j.neuroimage.2009.04.081
    ISSN 1095-9572
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19426817
    Accessed Sat Sep 26 15:33:31 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19426817
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • The brain and the cardiovascular system influence each other during the processing of emotion. The study of the interactions of these systems during emotion regulation has been limited in human functional neuroimaging, despite its potential importance for physical health. We have previously reported that mental expertise in cultivation of compassion alters the activation of circuits linked with empathy and theory of mind in response to emotional stimuli. Guided by the finding that heart rate increases more during blocks of compassion meditation than neutral states, especially for experts, we examined the interaction between state (compassion vs. neutral) and group (novice, expert) on the relation between heart rate and BOLD signal during presentation of emotional sounds presented during each state. Our findings revealed that BOLD signal in the right middle insula showed a significant association with heart rate (HR) across state and group. This association was stronger in the left middle/posterior insula when experts were compared to novices. The positive coupling of HR and BOLD was higher within the compassion state than within the neutral state in the dorsal anterior cingulate cortex for both groups, underlining the role of this region in the modulation of bodily arousal states. This state effect was stronger for experts than novices in somatosensory cortices and the right inferior parietal lobule (group by state interaction). These data confirm that compassion enhances the emotional and somatosensory brain representations of others’ emotions, and that this effect is modulated by expertise. Future studies are needed to further investigate the impact of compassion training on these circuits.

  • The Effect of Meditation on Neural Systems Implicated in Social Judgments

    Type Journal Article
    Author M Ly
    Author ML Spezio
    Abstract Introduction Meditation practices are often purported to have beneficial consequences on one's attentional performance or on one's capacity for positive behaviors in social interactions. Meditation is defined as a self-directed practice with a goal of suspending discursive and evaluative thought. Previous research on meditation, mainly within Eastern traditions such as Buddhism, have been shown to have an effect on systems of attention (Lutz et al., 2008; Slagter et al., 2007); thus, consequently, meditation has been adopted as a significant form of mind-body intervention within clinical healthcare with promising results including decreased levels of stress, chronic pain and anxiety. However, it is not known whether these practices may influence social decision-making. Using functional magnetic resonance imaging (fMRI), we investigated whether neural areas that were differentially activated by meditation continued to be recruited during simple judgments involving making trustworthiness attributions from just visual facial images. Methods Using a within subjects experimental design, experienced practitioners either meditated or focused attention on an audio narrative and signaled via button press when mind wandering occurred. Subsequently, participants made trustworthiness judgments based on facial images presented for 50 milliseconds, preceded by 10 minutes of either meditating or focusing on the narrative. Results During meditation, mindfulness in contrast to mind wandering recruited a greater activation in the bilateral insula and paracingulate [Figure 1]. Mindfulness during meditation in contrast to focused listening was associated with greater activation in the anterior cingulate cortex (ACC), dorsomedial prefrontal cortex and right precuneus [Figure 2]. Meditation prior to making trustworthiness judgments elicited increased activation in the left lateralized insula, inferofrontal gyrus and ventral anterior cingulate cortex (vACC) [Figure 3]. In contrast to focused listening, meditation was associated with a larger recruitment of the left insula, ACC, and right parietal cortex [Figure 4]. Conclusions We have shown that mindfulness during meditation recruits networks associated with attention and affective processing and in a differentially increased manner in contrast to focused listening. When compared to focused listening, meditation prior to social decision making was associated with greater recruitment of areas implicated in processing attention, emotion and interoception. These findings suggest that meditation may influence neural circuits in an enduring manner in which they may be easily recruited during social cognition. In a recent review, Craig (2009) proposed that the insula and ACC be regarded as limbic sensory and motor cortices that produce the feeling and motivation that compose an emotion. This theory is based on the dual lamina I spinothalamocortical projection to both the insula and the ACC, recruitment of both of these areas in numerous studies investigating emotion and their respective descending projections to sensory and motor brainstem regions. It is also suggested that the co-activation of the ACC and insula are associated with greater emotional and self-conscious awareness (Seeley et al., 2007; Craig, 2009). Further analyses on the functional connectivity between the insula and ACC will be conducted to further extend these findings.
    Publication NeuroImage
    Volume 47
    Issue Supplement 1
    Pages S194
    Date July 2009
    DOI 10.1016/S1053-8119(09)72190-1
    ISSN 1053-8119
    URL http://www.sciencedirect.com.ezproxy.bu.edu/science/article/B6WNP-4X3PHYG-2S6/2/c29afb2ec44a0cbec39a769a5cfb1689
    Accessed Sat Sep 26 18:25:24 2009
    Library Catalog ScienceDirect
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Introduction Meditation practices are often purported to have beneficial consequences on one’s attentional performance or on one’s capacity for positive behaviors in social interactions. Meditation is defined as a self-directed practice with a goal of suspending discursive and evaluative thought. Previous research on meditation, mainly within Eastern traditions such as Buddhism, have been shown to have an effect on systems of attention (Lutz et al., 2008; Slagter et al., 2007); thus, consequently, meditation has been adopted as a significant form of mind-body intervention within clinical healthcare with promising results including decreased levels of stress, chronic pain and anxiety. However, it is not known whether these practices may influence social decision-making. Using functional magnetic resonance imaging (fMRI), we investigated whether neural areas that were differentially activated by meditation continued to be recruited during simple judgments involving making trustworthiness attributions from just visual facial images. Methods: Using a within subjects experimental design, experienced practitioners either meditated or focused attention on an audio narrative and signaled via button press when mind wandering occurred. Subsequently, participants made trustworthiness judgments based on facial images presented for 50 milliseconds, preceded by 10 minutes of either meditating or focusing on the narrative. Results: During meditation, mindfulness in contrast to mind wandering recruited a greater activation in the bilateral insula and paracingulate [Figure 1]. Mindfulness during meditation in contrast to focused listening was associated with greater activation in the anterior cingulate cortex (ACC), dorsomedial prefrontal cortex and right precuneus [Figure 2]. Meditation prior to making trustworthiness judgments elicited increased activation in the left lateralized insula, inferofrontal gyrus and ventral anterior cingulate cortex (vACC) [Figure 3]. In contrast to focused listening, meditation was associated with a larger recruitment of the left insula, ACC, and right parietal cortex [Figure 4]. Conclusions: We have shown that mindfulness during meditation recruits networks associated with attention and affective processing and in a differentially increased manner in contrast to focused listening. When compared to focused listening, meditation prior to social decision making was associated with greater recruitment of areas implicated in processing attention, emotion and interoception. These findings suggest that meditation may influence neural circuits in an enduring manner in which they may be easily recruited during social cognition. In a recent review, Craig (2009) proposed that the insula and ACC be regarded as limbic sensory and motor cortices that produce the feeling and motivation that compose an emotion. This theory is based on the dual lamina I spinothalamocortical projection to both the insula and the ACC, recruitment of both of these areas in numerous studies investigating emotion and their respective descending projections to sensory and motor brainstem regions. It is also suggested that the co-activation of the ACC and insula are associated with greater emotional and self-conscious awareness (Seeley et al., 2007; Craig, 2009). Further analyses on the functional connectivity between the insula and ACC will be conducted to further extend these findings.

  • Cortisol as a marker for improvement in mindfulness-based stress reduction

    Type Journal Article
    Author Rose H. Matousek
    Author Patricia L. Dobkin
    Author Jens Pruessner
    Abstract While much attention has been devoted to examining the beneficial effects of Mindfulness-Based Stress Reduction programs on patients' ability to cope with various chronic medical conditions, most studies have relied on self-report measures of improvement. Given that these measures may not accurately reflect physiological conditions, there is a need for an objective marker of improvement in research evaluating the beneficial effects of stress management programs. Cortisol is the major stress hormone in the human organism and as such is a promising candidate measure in the study of the effects of Mindfulness-Based Stress Reduction programs. In conjunction with other biological measures, the use of cortisol levels as a physiological marker of stress may be useful to validate self-reported benefits attributed to this program. In the current manuscript, we review the available literature on the role of cortisol as a physiological marker for improvement with regards to mindfulness practice, and make recommendations for future study designs.
    Publication Complementary Therapies in Clinical Practice
    Volume 16
    Issue 1
    Pages 13-19
    Date February 2010
    DOI 10.1016/j.ctcp.2009.06.004
    ISSN 1744-3881
    Accessed Sat Mar 6 10:03:23 2010
    Library Catalog ScienceDirect
    Date Added Thu Sep 29 09:04:35 2011
    Modified Thu Sep 29 09:04:35 2011

    Tags:

    • Cortisol
    • Mbsr
    • Meditation
    • Mindfulness-Based Stress Reduction
    • Stress
  • Using mindfulness meditation to teach beginning therapists therapeutic presence: a qualitative study

    Type Journal Article
    Author Eric E McCollum
    Author Diane R Gehart
    Abstract Some of the more difficult to define aspects of the therapeutic process (empathy, compassion, presence) remain some of the most important. Teaching them presents a challenge for therapist trainees and educators alike. In this study, we examine our beginning practicum students' experience of learning mindfulness meditation as a way to help them develop therapeutic presence. Through thematic analysis of their journal entries a variety of themes emerged, including the effects of meditation practice, the ability to be present, balancing being and doing modes in therapy, and the development of acceptance and compassion for themselves and for their clients. Our findings suggest that mindfulness meditation may be a useful addition to clinical training.
    Publication Journal of Marital and Family Therapy
    Volume 36
    Issue 3
    Pages 347-360
    Date Jul 1, 2010
    Journal Abbr J Marital Fam Ther
    DOI 10.1111/j.1752-0606.2010.00214.x
    ISSN 1752-0606
    Short Title Using mindfulness meditation to teach beginning therapists therapeutic presence
    Accessed Tue Jul 27 11:57:18 2010
    Library Catalog NCBI PubMed
    Extra PMID: 20618581
    Date Added Thu Sep 29 09:03:48 2011
    Modified Thu Sep 29 09:03:48 2011
  • Teaching Mindfulness: A Practical Guide for Clinicians and Educators

    Type Book
    Author Donald McCown
    Author Diane Reibel
    Author Marc S. Micozzi
    Place New York
    Publisher Springer
    Date 2009-12-15
    ISBN 0387094830
    Short Title Teaching Mindfulness
    Library Catalog Amazon.com
    Date Added Thu Sep 29 09:05:21 2011
    Modified Thu Sep 29 09:05:21 2011
  • Meditation, mindfulness and cognitive flexibility

    Type Journal Article
    Author Adam Moore
    Author Peter Malinowski
    Abstract This study investigated the link between meditation, self-reported mindfulness and cognitive flexibility as well as other attentional functions. It compared a group of meditators experienced in mindfulness meditation with a meditation-naïve control group on measures of Stroop interference and the "d2-concentration and endurance test". Overall the results suggest that attentional performance and cognitive flexibility are positively related to meditation practice and levels of mindfulness. Meditators performed significantly better than non-meditators on all measures of attention. Furthermore, self-reported mindfulness was higher in meditators than non-meditators and correlations with all attention measures were of moderate to high strength. This pattern of results suggests that mindfulness is intimately linked to improvements of attentional functions and cognitive flexibility. The relevance of these findings for mental balance and well-being are discussed.
    Publication Consciousness and Cognition
    Volume 18
    Issue 1
    Pages 176-186
    Date Mar 2009
    Journal Abbr Conscious Cogn
    DOI 10.1016/j.concog.2008.12.008
    ISSN 1090-2376
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19181542
    Accessed Sat Sep 26 15:22:22 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19181542
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Attention
    • Cognition
    • Humans
    • Meditation

    Notes:

    • This study investigated the link between meditation, self-reported mindfulness and cognitive flexibility as well as other attentional functions. It compared a group of meditators experienced in mindfulness meditation with a meditation-naïve control group on measures of Stroop interference and the “d2-concentration and endurance test”. Overall the results suggest that attentional performance and cognitive flexibility are positively related to meditation practice and levels of mindfulness. Meditators performed significantly better than non-meditators on all measures of attention. Furthermore, self-reported mindfulness was higher in meditators than non-meditators and correlations with all attention measures were of moderate to high strength. This pattern of results suggests that mindfulness is intimately linked to improvements of attentional functions and cognitive flexibility. The relevance of these findings for mental balance and well-being are discussed.

  • A randomized controlled trial on effects of the Transcendental Meditation program on blood pressure, psychological distress, and coping in young adults

    Type Journal Article
    Author Sanford I Nidich
    Author Maxwell V Rainforth
    Author David A F Haaga
    Author John Hagelin
    Author John W Salerno
    Author Fred Travis
    Author Melissa Tanner
    Author Carolyn Gaylord-King
    Author Sarina Grosswald
    Author Robert H Schneider
    Abstract BACKGROUND: Psychological distress contributes to the development of hypertension in young adults. This trial assessed the effects of a mind-body intervention on blood pressure (BP), psychological distress, and coping in college students. METHODS: This was a randomized controlled trial (RCT) of 298 university students randomly allocated to either the Transcendental Meditation (TM) program or wait-list control. At baseline and after 3 months, BP, psychological distress, and coping ability were assessed. A subgroup of 159 subjects at risk for hypertension was analyzed similarly. RESULTS: Changes in systolic BP (SBP)/diastolic BP (DBP) for the overall sample were -2.0/-1.2 mm Hg for the TM group compared to +0.4/+0.5 mm Hg for controls (P = 0.15, P = 0.15, respectively). Changes in SBP/DBP for the hypertension risk subgroup were -5.0/-2.8 mm Hg for the TM group compared to +1.3/+1.2 mm Hg for controls (P = 0.014, P = 0.028, respectively). Significant improvements were found in total psychological distress, anxiety, depression, anger/hostility, and coping (P values < 0.05). Changes in psychological distress and coping correlated with changes in SBP (P values < 0.05) and DBP (P values < 0.08). CONCLUSIONS: This is the first RCT to demonstrate that a selected mind-body intervention, the TM program, decreased BP in association with decreased psychological distress, and increased coping in young adults at risk for hypertension. This mind-body program may reduce the risk for future development of hypertension in young adults.
    Publication American Journal of Hypertension
    Volume 22
    Issue 12
    Pages 1326-1331
    Date Dec 2009
    Journal Abbr Am. J. Hypertens
    DOI 10.1038/ajh.2009.184
    ISSN 1879-1905
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19798037
    Accessed Mon Dec 28 11:55:05 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19798037
    Date Added Thu Sep 29 09:04:55 2011
    Modified Thu Sep 29 09:04:55 2011
  • Passage meditation reduces perceived stress in health professionals: a randomized, controlled trial

    Type Journal Article
    Author Doug Oman
    Author John Hedberg
    Author Carl E Thoresen
    Abstract The authors evaluated an 8-week, 2-hr per week training for physicians, nurses, chaplains, and other health professionals using nonsectarian, spiritually based self-management tools based on passage meditation (E. Easwaran, 1978/1991). Participants were randomized to intervention (n = 27) or waiting list (n = 31). Pretest, posttest, and 8- and 19-week follow-up data were gathered on 8 measures, including perceived stress, burnout, mental health, and psychological well-being. Aggregated across examinations, beneficial treatment effects were observed on stress (p = .0013) and mental health (p = .03). Treatment effects on stress were mediated by adherence to practices (p = .05). Stress reductions remained large at 19 weeks (84% of the pretest standard deviation, p = .006). Evidence suggests this program reduces stress and may enhance mental health.
    Publication Journal of Consulting and Clinical Psychology
    Volume 74
    Issue 4
    Pages 714-719
    Date Aug 2006
    Journal Abbr J Consult Clin Psychol
    DOI 10.1037/0022-006X.74.4.714
    ISSN 0022-006X
    Short Title Passage meditation reduces perceived stress in health professionals
    URL http://www.ncbi.nlm.nih.gov/pubmed/16881779
    Accessed Fri Nov 13 16:47:42 2009
    Library Catalog NCBI PubMed
    Extra PMID: 16881779
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adult
    • Female
    • Health Personnel
    • Humans
    • Male
    • Meditation
    • Psychological Theory
    • spirituality
    • Stress, Psychological

    Notes:

    • The authors evaluated an 8-week, 2-hr per week training for physicians, nurses, chaplains, and other health professionals using nonsectarian, spiritually based self-management tools based on passage meditation (E. Easwaran, 1978/1991). Participants were randomized to intervention (n = 27) or waiting list (n = 31). Pretest, posttest, and 8- and 19-week follow-up data were gathered on 8 measures, including perceived stress, burnout, mental health, and psychological well-being. Aggregated across examinations, beneficial treatment effects were observed on stress (p = .0013) and mental health (p = .03). Treatment effects on stress were mediated by adherence to practices (p = .05). Stress reductions remained large at 19 weeks (84% of the pretest standard deviation, p = .006). Evidence suggests this program reduces stress and may enhance mental health.

  • Innate immune, neuroendocrine and behavioral responses to psychosocial stress do not predict subsequent compassion meditation practice time

    Type Journal Article
    Author Thaddeus W.W. Pace
    Author Lobsang Tenzin Negi
    Author Teresa I. Sivilli
    Author Michael J. Issa
    Author Steven P. Cole
    Author Daniel D. Adame
    Author Charles L. Raison
    Abstract Summary Increasing data suggest that meditation impacts stress-related physiological processes relevant to health and disease. For example, our group recently reported that the practice of compassion meditation was associated with reduced innate immune (plasma interleukin [IL]-6) and subjective distress responses to a standardized laboratory psychosocial stressor (Trier Social Stress Test [TSST]). However, because we administered a TSST after, but not prior to, meditation training in our initial study, it remained possible that associations between practice time and TSST outcomes reflected the fact that participants with reduced stress responses prior to training were more able to practice compassion meditation, rather than that meditation practice reduced stress responses. To help resolve this ambiguity, we conducted the current study to evaluate whether innate immune, neuroendocrine and behavioral responses to a TSST conducted prior to compassion meditation training in an independent sample of 32 medically health young adults would predict subsequent amount of meditation practice time during a compassion meditation training protocol identical to the one used in our first study. No associations were found between responses to a TSST administered prior to compassion meditation training and subsequent amount of meditation practice, whether practice time was considered as a continuous variable or whether meditators were divided into high and low practice time groups based on a median split of mean number of practice sessions per week. These findings contrast strikingly with our original study, in which high and low practice time meditators demonstrated marked differences in IL-6 and distress responses to a TSST administered after meditation training. In addition to providing the first published data regarding stress responsivity as a potential predictor of subsequent ability/willingness to practice meditation, the current study strengthens findings from our initial work by supporting the conclusion that in individuals who actively engage in practicing the technique, compassion meditation may represent a viable strategy for reducing potentially deleterious physiological and behavioral responses to psychosocial stress.
    Publication Psychoneuroendocrinology
    Volume 35
    Issue 2
    Pages 310-315
    Date February 2010
    DOI 10.1016/j.psyneuen.2009.06.008
    ISSN 0306-4530
    Accessed Sat Mar 6 10:10:15 2010
    Library Catalog ScienceDirect
    Date Added Thu Sep 29 09:04:02 2011
    Modified Thu Sep 29 09:04:02 2011

    Tags:

    • Compassion
    • Cortisol
    • Interleukin-6
    • Meditation
    • Mindfulness
    • Trier Social Stress Test
  • Positive impact of cyclic meditation on subsequent sleep

    Type Journal Article
    Author Sanjib Patra
    Author Shirley Telles
    Abstract Cyclic meditation (CM) is a technique that combines yoga postures interspersed with supine rest. This combination is based on ancient texts and is considered easier for beginners to practice< Whole-night polysomnographic measures and the self-rating of sleep were studied on the night following a day in which 30 male participants practiced CM twice (ca. 23 minutes each time). This was compared with another night when they had had two sessions of supine rest (SR) of equal duration on the preceding day. The sessions were one day apart and the order of the sessions was randomized. Recordings were from the F4, C4, and O2 electrode sites referenced to linked earlobes and bipolar electroculography and electromyography sites In the night following CM, the percentage of slow-wave sleep (SWS) was significantly higher than in the night following SR, whereas the percentage of rapid-eye-movement (REM) sleep and the number of awakenings per hour were less. Following CM the self-rating of sleep based on visual analog scales showed an increase in the feeling that the sleep was refreshing, an increase in feeling "good" in the morning, an overall increase in sleep duration, and decreases in the degree to which sleep was influenced by being in a laboratory as well as any associated discomfort. Practicing cyclic meditation twice a day appeared to improve the objective and subjective quality of sleep on the following night.
    Publication Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
    Volume 15
    Issue 7
    Pages CR375-381
    Date Jul 2009
    Journal Abbr Med. Sci. Monit
    ISSN 1643-3750
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19564829
    Accessed Fri Feb 4 11:17:04 2011
    Library Catalog NCBI PubMed
    Extra PMID: 19564829
    Date Added Thu Sep 29 09:05:38 2011
    Modified Thu Sep 29 09:05:38 2011

    Tags:

    • Adult
    • Humans
    • Male
    • Meditation
    • Polysomnography
    • Rest
    • Sleep
    • yoga
  • Heart Rate Variability During Sleep Following the Practice of Cyclic Meditation and Supine Rest

    Type Journal Article
    Author S. Patra
    Author S. Telles
    Abstract Day time activities are known to influence the sleep on the following night. Cyclic meditation (CM) has recurring cycles. Previously, the low frequency (LF) power and the ratio between low frequency and high frequency (LF/HF ratio) of the heart rate variability (HRV) decreased during and after CM but not after a comparable period of supine rest (SR). In the present study, on thirty male volunteers, CM was practiced twice in the day and after this the HRV was recorded (1) while awake and (2) during 6 h of sleep (based on EEG, EMG and EGG recordings). This was similarly recorded for the night's sleep following the day time practice of SR. Participants were randomly assigned to the two sessions and all of them practiced both CM and SR on different days. During the night following day time CM practice there were the following changes; a decrease in heart rate, LF power (n.u.), LF/HF ratio, and an increase in the number of pairs of Normal to Normal RR intervals differing by more than 50 ms divided by total number of all NN intervals (pNN50) (P < 0.05, in all cases, comparing sleep following CM compared with sleep following SR). No change was seen on the night following SR. Hence yoga practice during the day appears to shift sympatho-vagal balance in favor of parasympathetic dominance during sleep on the following night.
    Publication Applied Psychophysiology and Biofeedback
    Volume 35
    Issue 2
    Pages 135-140
    Date JUN 2010
    DOI 10.1007/s10484-009-9114-1
    ISSN 1090-0586
    Accessed Tue Jun 15 10:50:56 2010
    Library Catalog ISI Web of Knowledge
    Date Added Thu Sep 29 09:04:02 2011
    Modified Thu Sep 29 09:04:02 2011
  • Stress reduction programs in patients with elevated blood pressure: a systematic review and meta-analysis

    Type Journal Article
    Author Maxwell V Rainforth
    Author Robert H Schneider
    Author Sanford I Nidich
    Author Carolyn Gaylord-King
    Author John W Salerno
    Author James W Anderson
    Abstract Substantial evidence indicates that psychosocial stress contributes to hypertension and cardiovascular disease (CVD). Previous meta-analyses of stress reduction and high blood pressure (BP) were outdated and/or methodologically limited. Therefore, we conducted an updated systematic review of the published literature and identified 107 studies on stress reduction and BP. Seventeen trials with 23 treatment comparisons and 960 participants with elevated BP met criteria for well-designed randomized controlled trials and were replicated within intervention categories. Meta-analysis was used to calculate BP changes for biofeedback, -0.8/-2.0 mm Hg (P = NS); relaxation-assisted biofeedback, +4.3/+2.4 mm Hg (P = NS); progressive muscle relaxation, -1.9/-1.4 mm Hg (P = NS); stress management training, -2.3/-1.3 mm (P = NS); and the Transcendental Meditation program, -5.0/-2.8 mm Hg (P = 0.002/0.02). Available evidence indicates that among stress reduction approaches, the Transcendental Meditation program is associated with significant reductions in BP. Related data suggest improvements in other CVD risk factors and clinical outcomes.
    Publication Current Hypertension Reports
    Volume 9
    Issue 6
    Pages 520-528
    Date Dec 2007
    Journal Abbr Curr. Hypertens. Rep
    ISSN 1522-6417
    Short Title Stress reduction programs in patients with elevated blood pressure
    URL http://www.ncbi.nlm.nih.gov/pubmed/18350109
    Accessed Thu Sep 3 00:55:23 2009
    Library Catalog NCBI PubMed
    Extra PMID: 18350109
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Biofeedback (Psychology)
    • Blood Pressure
    • Cardiovascular Diseases
    • Evidence-Based Medicine
    • Humans
    • Hypertension
    • Meditation
    • Stress, Psychological

    Notes:

    • Substantial evidence indicates that psychosocial stress contributes to hypertension and cardiovascular disease (CVD). Previous meta-analyses of stress reduction and high blood pressure (BP) were outdated and/or methodologically limited. Therefore, we conducted an updated systematic review of the published literature and identified 107 studies on stress reduction and BP. Seventeen trials with 23 treatment comparisons and 960 participants with elevated BP met criteria for well-designed randomized controlled trials and were replicated within intervention categories. Meta-analysis was used to calculate BP changes for biofeedback, -0.8/-2.0 mm Hg (P = NS); relaxation-assisted biofeedback, +4.3/+2.4 mm Hg (P = NS); progressive muscle relaxation, -1.9/-1.4 mm Hg (P = NS); stress management training, -2.3/-1.3 mm (P = NS); and the Transcendental Meditation program, -5.0/-2.8 mm Hg (P = 0.002/0.02). Available evidence indicates that among stress reduction approaches, the Transcendental Meditation program is associated with significant reductions in BP. Related data suggest improvements in other CVD risk factors and clinical outcomes.

  • Theta phase synchrony and conscious target perception: impact of intensive mental training

    Type Journal Article
    Author Heleen A Slagter
    Author Antoine Lutz
    Author Lawrence L Greischar
    Author Sander Nieuwenhuis
    Author Richard J Davidson
    Abstract The information processing capacity of the human mind is limited, as is evidenced by the attentional blink-a deficit in identifying the second of two targets (T1 and T2) presented in close succession. This deficit is thought to result from an overinvestment of limited resources in T1 processing. We previously reported that intensive mental training in a style of meditation aimed at reducing elaborate object processing, reduced brain resource allocation to T1, and improved T2 accuracy [Slagter, H. A., Lutz, A., Greischar, L. L., Francis, A. D., Nieuwenhuis, S., Davis, J., et al. Mental training affects distribution of limited brain resources. PloS Biology, 5, e138, 2007]. Here we report EEG spectral analyses to examine the possibility that this reduction in elaborate T1 processing rendered the system more available to process new target information, as indexed by T2-locked phase variability. Intensive mental training was associated with decreased cross-trial variability in the phase of oscillatory theta activity after successfully detected T2s, in particular, for those individuals who showed the greatest reduction in brain resource allocation to T1. These data implicate theta phase locking in conscious target perception, and suggest that after mental training the cognitive system is more rapidly available to process new target information. Mental training was not associated with changes in the amplitude of T2-induced responses or oscillatory activity before task onset. In combination, these findings illustrate the usefulness of systematic mental training in the study of the human mind by revealing the neural mechanisms that enable the brain to successfully represent target information.
    Publication Journal of Cognitive Neuroscience
    Volume 21
    Issue 8
    Pages 1536-1549
    Date Aug 2009
    Journal Abbr J Cogn Neurosci
    DOI 10.1162/jocn.2009.21125
    ISSN 0898-929X
    Short Title Theta phase synchrony and conscious target perception
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/18823234
    Accessed Sat Sep 26 15:43:27 2009
    Library Catalog NCBI PubMed
    Extra PMID: 18823234
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adult
    • Analysis of Variance
    • Attentional Blink
    • Brain Mapping
    • Consciousness
    • Contingent Negative Variation
    • Female
    • Humans
    • Male
    • Middle Aged
    • Negotiating
    • Photic Stimulation
    • Reaction Time
    • Theta Rhythm
    • Time Factors
    • Young Adult

    Notes:

    • The information processing capacity of the human mind is limited, as is evidenced by the attentional blink-a deficit in identifying the second of two targets (T1 and T2) presented in close succession. This deficit is thought to result from an overinvestment of limited resources in T1 processing. We previously reported that intensive mental training in a style of meditation aimed at reducing elaborate object processing, reduced brain resource allocation to T1, and improved T2 accuracy [Slagter, H. A., Lutz, A., Greischar, L. L., Francis, A. D., Nieuwenhuis, S., Davis, J., et al. Mental training affects distribution of limited brain resources. PloS Biology, 5, e138, 2007]. Here we report EEG spectral analyses to examine the possibility that this reduction in elaborate T1 processing rendered the system more available to process new target information, as indexed by T2-locked phase variability. Intensive mental training was associated with decreased cross-trial variability in the phase of oscillatory theta activity after successfully detected T2s, in particular, for those individuals who showed the greatest reduction in brain resource allocation to T1. These data implicate theta phase locking in conscious target perception, and suggest that after mental training the cognitive system is more rapidly available to process new target information. Mental training was not associated with changes in the amplitude of T2-induced responses or oscillatory activity before task onset. In combination, these findings illustrate the usefulness of systematic mental training in the study of the human mind by revealing the neural mechanisms that enable the brain to successfully represent target information.

  • Fully present : the science, art, and practice of mindfulness

    Type Book
    Author Susan Smalley
    Place Cambridge Mass.
    Publisher Da Capo Lifelong
    Date 2010
    ISBN 9780738213248
    Date Added Thu Sep 29 09:03:48 2011
    Modified Thu Sep 29 09:03:48 2011
  • Effect of two yoga-based relaxation techniques on memory scores and state anxiety

    Type Journal Article
    Author Pailoor Subramanya
    Author Shirley Telles
    Abstract ABSTRACT: BACKGROUND: A yoga practice involving cycles of yoga postures and supine rest (called cyclic meditation) was previously shown to improve performance in attention tasks more than relaxation in the corpse posture (shavasana). This was ascribed to reduced anxiety, though this was not assessed. METHODS: In fifty-seven male volunteers (group average age +/- S.D., 26.6 +/- 4.5 years) the immediate effect of two yoga relaxation techniques was studied on memory and state anxiety. All participants were assessed before and after (i) Cyclic meditation (CM) practiced for 22:30 minutes on one day and (ii) an equal duration of Supine rest (SR) or the corpse posture (shavasana), on another day. Sections of the Wechsler memory scale (WMS) were used to assess; (i) attention and concentration (digit span forward and backward), and (ii) associate learning. State anxiety was assessed using Spielberger's State-Trait Anxiety Inventory (STAI). RESULTS: There was a significant improvement in the scores of all sections of the WMS studied after both CM and SR, but, the magnitude of change was more after CM compared to after SR. The state anxiety scores decreased after both CM and SR, with a greater magnitude of decrease after CM. There was no correlation between percentage change in memory scores and state anxiety for either session. CONCLUSION: A cyclical combination of yoga postures and supine rest in CM improved memory scores immediately after the practice and decreased state anxiety more than rest in a classical yoga relaxation posture (shavasana).
    Publication BioPsychoSocial Medicine
    Volume 3
    Pages 8
    Date Aug 2009
    Journal Abbr Biopsychosoc Med
    DOI 10.1186/1751-0759-3-8
    ISSN 1751-0759
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19674483
    Accessed Sat Sep 26 15:07:04 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19674483
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Background: A yoga practice involving cycles of yoga postures and supine rest (called cyclic meditation) was previously shown to improve performance in attention tasks more than relaxation in the corpse posture (shavasana). This was ascribed to reduced anxiety, though this was not assessed. Methods: In fifty-seven male volunteers (group average age +/- S.D., 26.6 +/- 4.5 years) the immediate effect of two yoga relaxation techniques was studied on memory and state anxiety. All participants were assessed before and after (i) Cyclic meditation (CM) practiced for 22:30 minutes on one day and (ii) an equal duration of Supine rest (SR) or the corpse posture (shavasana), on another day. Sections of the Wechsler memory scale (WMS) were used to assess; (i) attention and concentration (digit span forward and backward), and (ii) associate learning. State anxiety was assessed using Spielberger’s State-Trait Anxiety Inventory (STAI). Results: There was a significant improvement in the scores of all sections of the WMS studied after both CM and SR, but, the magnitude of change was more after CM compared to after SR. The state anxiety scores decreased after both CM and SR, with a greater magnitude of decrease after CM. There was no correlation between percentage change in memory scores and state anxiety for either session. Conclusion: A cyclical combination of yoga postures and supine rest in CM improved memory scores immediately after the practice and decreased state anxiety more than rest in a classical yoga relaxation posture (shavasana).

  • Changes in midlatency auditory evoked potentials following two yoga-based relaxation techniques

    Type Journal Article
    Author Pailoor Subramanya
    Author Shirley Telles
    Abstract Practicing meditation while focusing on a sound or a symbol influenced midlatency auditory evoked potentials (MLAEPs). Cyclic meditation (CM) is a technique combining yoga postures with meditation while supine, which has influenced the P300 event-related potential. The effects of CM on MLAEPs have not been previously studied. The MLAEPs were studied before and after the practice of CM compared to an equal duration of supine rest (SR) in 47 male volunteers (group mean age 26.5 +/- 4.4 years), recorded from the vertex referenced to linked earlobes. The sessions were one day apart and subjects were randomly assigned to each session. The Pa wave peak latency and Nb wave peak latency significantly increased following CM compared to before CM (repeated measures ANOVA, post-hoc analysis with least significant difference, p<0.05). There was a significant increase in the peak amplitude of the Nb wave (p<0.05) compared to before CM. Post SR there was a significant increase in the peak latency of the Na wave (p<0.05) compared to before SR. In conclusion following CM the latencies of neural generators corresponding to cortical areas is prolonged, whereas following SR a similar change occurs at mesencephalic-diencephalic levels.
    Publication Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
    Volume 40
    Issue 3
    Pages 190-195
    Date Jul 2009
    Journal Abbr Clin EEG Neurosci
    ISSN 1550-0594
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19715182
    Accessed Sat Sep 26 15:45:39 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19715182
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Practicing meditation while focusing on a sound or a symbol influenced midlatency auditory evoked potentials (MLAEPs). Cyclic meditation (CM) is a technique combining yoga postures with meditation while supine, which has influenced the P300 event-related potential. The effects of CM on MLAEPs have not been previously studied. The MLAEPs were studied before and after the practice of CM compared to an equal duration of supine rest (SR) in 47 male volunteers (group mean age 26.5 +/- 4.4 years), recorded from the vertex referenced to linked earlobes. The sessions were one day apart and subjects were randomly assigned to each session. The Pa wave peak latency and Nb wave peak latency significantly increased following CM compared to before CM (repeated measures ANOVA, post-hoc analysis with least significant difference, p<0.05). There was a significant increase in the peak amplitude of the Nb wave (p<0.05) compared to before CM. Post SR there was a significant increase in the peak latency of the Na wave (p<0.05) compared to before SR. In conclusion following CM the latencies of neural generators corresponding to cortical areas is prolonged, whereas following SR a similar change occurs at mesencephalic-diencephalic levels.

  • Central and autonomic nervous system interaction is altered by short-term meditation

    Type Journal Article
    Author Yi-Yuan Tang
    Author Yinghua Ma
    Author Yaxin Fan
    Author Hongbo Feng
    Author Junhong Wang
    Author Shigang Feng
    Author Qilin Lu
    Author Bing Hu
    Author Yao Lin
    Author Jian Li
    Author Ye Zhang
    Author Yan Wang
    Author Li Zhou
    Author Ming Fan
    Abstract Five days of integrative body-mind training (IBMT) improves attention and self-regulation in comparison with the same amount of relaxation training. This paper explores the underlying mechanisms of this finding. We measured the physiological and brain changes at rest before, during, and after 5 days of IBMT and relaxation training. During and after training, the IBMT group showed significantly better physiological reactions in heart rate, respiratory amplitude and rate, and skin conductance response (SCR) than the relaxation control. Differences in heart rate variability (HRV) and EEG power suggested greater involvement of the autonomic nervous system (ANS) in the IBMT group during and after training. Imaging data demonstrated stronger subgenual and adjacent ventral anterior cingulate cortex (ACC) activity in the IBMT group. Frontal midline ACC theta was correlated with high-frequency HRV, suggesting control by the ACC over parasympathetic activity. These results indicate that after 5 days of training, the IBMT group shows better regulation of the ANS by a ventral midfrontal brain system than does the relaxation group. This changed state probably reflects training in the coordination of body and mind given in the IBMT but not in the control group. These results could be useful in the design of further specific interventions.
    Publication Proceedings of the National Academy of Sciences of the United States of America
    Volume 106
    Issue 22
    Pages 8865-8870
    Date Jun 2, 2009
    Journal Abbr Proc. Natl. Acad. Sci. U.S.A
    DOI 10.1073/pnas.0904031106
    ISSN 1091-6490
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19451642
    Accessed Tue Sep 8 16:46:37 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19451642
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Autonomic Nervous System
    • Brain
    • Brain Mapping
    • Exercise
    • Female
    • Humans
    • Male
    • Meditation
    • Relaxation
    • Skin Physiological Phenomena
    • Young Adult

    Notes:

    • Five days of integrative body-mind training (IBMT) improves attention and self-regulation in comparison with the same amount of relaxation training. This paper explores the underlying mechanisms of this finding. We measured the physiological and brain changes at rest before, during, and after 5 days of IBMT and relaxation training. During and after training, the IBMT group showed significantly better physiological reactions in heart rate, respiratory amplitude and rate, and skin conductance response (SCR) than the relaxation control. Differences in heart rate variability (HRV) and EEG power suggested greater involvement of the autonomic nervous system (ANS) in the IBMT group during and after training. Imaging data demonstrated stronger subgenual and adjacent ventral anterior cingulate cortex (ACC) activity in the IBMT group. Frontal midline ACC theta was correlated with high-frequency HRV, suggesting control by the ACC over parasympathetic activity. These results indicate that after 5 days of training, the IBMT group shows better regulation of the ANS by a ventral midfrontal brain system than does the relaxation group. This changed state probably reflects training in the coordination of body and mind given in the IBMT but not in the control group. These results could be useful in the design of further specific interventions.

  • Central and autonomic nervous system interaction is altered by short-term meditation

    Type Journal Article
    Author Yi-Yuan Tang
    Author Yinghua Ma
    Author Yaxin Fan
    Author Hongbo Feng
    Author Junhong Wang
    Author Shigang Feng
    Author Qilin Lu
    Author Bing Hu
    Author Yao Lin
    Author Jian Li
    Author Ye Zhang
    Author Yan Wang
    Author Li Zhou
    Author Ming Fan
    Abstract Five days of integrative body-mind training (IBMT) improves attention and self-regulation in comparison with the same amount of relaxation training. This paper explores the underlying mechanisms of this finding. We measured the physiological and brain changes at rest before, during, and after 5 days of IBMT and relaxation training. During and after training, the IBMT group showed significantly better physiological reactions in heart rate, respiratory amplitude and rate, and skin conductance response (SCR) than the relaxation control. Differences in heart rate variability (HRV) and EEG power suggested greater involvement of the autonomic nervous system (ANS) in the IBMT group during and after training. Imaging data demonstrated stronger subgenual and adjacent ventral anterior cingulate cortex (ACC) activity in the IBMT group. Frontal midline ACC theta was correlated with high-frequency HRV, suggesting control by the ACC over parasympathetic activity. These results indicate that after 5 days of training, the IBMT group shows better regulation of the ANS by a ventral midfrontal brain system than does the relaxation group. This changed state probably reflects training in the coordination of body and mind given in the IBMT but not in the control group. These results could be useful in the design of further specific interventions.
    Publication Proceedings of the National Academy of Sciences of the United States of America
    Volume 106
    Issue 22
    Pages 8865-8870
    Date Jun 2, 2009
    Journal Abbr Proc. Natl. Acad. Sci. U.S.A
    DOI 10.1073/pnas.0904031106
    ISSN 1091-6490
    Accessed Tue Feb 22 19:07:23 2011
    Library Catalog NCBI PubMed
    Extra PMID: 19451642
    Date Added Thu Sep 29 09:06:18 2011
    Modified Thu Sep 29 09:06:18 2011

    Tags:

    • Autonomic Nervous System
    • Brain
    • Brain Mapping
    • Exercise
    • Female
    • Humans
    • Male
    • Meditation
    • Relaxation
    • Skin Physiological Phenomena
    • Young Adult
  • Short-term meditation training improves attention and self-regulation

    Type Journal Article
    Author Yi-Yuan Tang
    Author Yinghua Ma
    Author Junhong Wang
    Author Yaxin Fan
    Author Shigang Feng
    Author Qilin Lu
    Author Qingbao Yu
    Author Danni Sui
    Author Mary K Rothbart
    Author Ming Fan
    Author Michael I Posner
    Abstract Recent studies suggest that months to years of intensive and systematic meditation training can improve attention. However, the lengthy training required has made it difficult to use random assignment of participants to conditions to confirm these findings. This article shows that a group randomly assigned to 5 days of meditation practice with the integrative body-mind training method shows significantly better attention and control of stress than a similarly chosen control group given relaxation training. The training method comes from traditional Chinese medicine and incorporates aspects of other meditation and mindfulness training. Compared with the control group, the experimental group of 40 undergraduate Chinese students given 5 days of 20-min integrative training showed greater improvement in conflict scores on the Attention Network Test, lower anxiety, depression, anger, and fatigue, and higher vigor on the Profile of Mood States scale, a significant decrease in stress-related cortisol, and an increase in immunoreactivity. These results provide a convenient method for studying the influence of meditation training by using experimental and control methods similar to those used to test drugs or other interventions.
    Publication Proceedings of the National Academy of Sciences of the United States of America
    Volume 104
    Issue 43
    Pages 17152-17156
    Date Oct 23, 2007
    Journal Abbr Proc. Natl. Acad. Sci. U.S.A
    DOI 10.1073/pnas.0707678104
    ISSN 0027-8424
    URL http://www.ncbi.nlm.nih.gov/pubmed/17940025
    Accessed Thu Sep 3 01:22:45 2009
    Library Catalog NCBI PubMed
    Extra PMID: 17940025
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adult
    • Attention
    • Case-Control Studies
    • Female
    • Humans
    • Male
    • Meditation
    • Psychological Tests
    • Social Control, Informal
    • Time Factors

    Notes:

    • Recent studies suggest that months to years of intensive and systematic meditation training can improve attention. However, the lengthy training required has made it difficult to use random assignment of participants to conditions to confirm these findings. This article shows that a group randomly assigned to 5 days of meditation practice with the integrative body-mind training method shows significantly better attention and control of stress than a similarly chosen control group given relaxation training. The training method comes from traditional Chinese medicine and incorporates aspects of other meditation and mindfulness training. Compared with the control group, the experimental group of 40 undergraduate Chinese students given 5 days of 20-min integrative training showed greater improvement in conflict scores on the Attention Network Test, lower anxiety, depression, anger, and fatigue, and higher vigor on the Profile of Mood States scale, a significant decrease in stress-related cortisol, and an increase in immunoreactivity. These results provide a convenient method for studying the influence of meditation training by using experimental and control methods similar to those used to test drugs or other interventions.

  • The effects of the transcendental meditation program on mindfulness

    Type Journal Article
    Author Melissa A Tanner
    Author Fred Travis
    Author Carolyn Gaylord-King
    Author David A F Haaga
    Author Sarina Grosswald
    Author Robert H Schneider
    Abstract Mindfulness is associated with low levels of neuroticism, anxiety, and depressive symptoms, as well as high levels of self-esteem and satisfaction with life (Brown & Ryan, 2003). As part of a 3-month randomized waitlist-controlled trial of the effects of the Transcendental Meditation (TM) program on university students (N=295), we examined the impact of TM practice on mindfulness as measured by the Kentucky Inventory of Mindfulness Skills (KIMS; Baer, Smith, & Allen, 2004). A repeated measures ANOVA on total KIMS scores showed a significant timextreatment interaction, with the TM participants reporting greater increases in mindfulness than the waitlist participants. All KIMS subscales were positively intercorrelated at pretreatment, and there were no differences over time or as a function of treatment condition in subscale intercorrelations. Therefore, previously published findings of a positive correlation between subscales measuring the skills of observing and accepting-without-judgment one's inner experiences only among those with meditation experience may have reflected a self-selection effect rather than a change in the relation of these mindfulness components resulting directly from meditation practice.
    Publication Journal of Clinical Psychology
    Volume 65
    Issue 6
    Pages 574-589
    Date Jun 2009
    Journal Abbr J Clin Psychol
    DOI 10.1002/jclp.20544
    ISSN 1097-4679
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19241401
    Accessed Sat Sep 26 15:17:57 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19241401
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Adult
    • Analysis of Variance
    • Attention
    • Awareness
    • Female
    • Humans
    • Male
    • Meditation
    • Questionnaires
    • Students
    • Young Adult

    Notes:

    • Mindfulness is associated with low levels of neuroticism, anxiety, and depressive symptoms, as well as high levels of self-esteem and satisfaction with life (Brown & Ryan, 2003). As part of a 3-month randomized waitlist-controlled trial of the effects of the Transcendental Meditation (TM) program on university students (N=295), we examined the impact of TM practice on mindfulness as measured by the Kentucky Inventory of Mindfulness Skills (KIMS; Baer, Smith, & Allen, 2004). A repeated measures ANOVA on total KIMS scores showed a significant timextreatment interaction, with the TM participants reporting greater increases in mindfulness than the waitlist participants. All KIMS subscales were positively intercorrelated at pretreatment, and there were no differences over time or as a function of treatment condition in subscale intercorrelations. Therefore, previously published findings of a positive correlation between subscales measuring the skills of observing and accepting-without-judgment one’s inner experiences only among those with meditation experience may have reflected a self-selection effect rather than a change in the relation of these mindfulness components resulting directly from meditation practice.

  • Meditators and non-meditators: EEG source imaging during resting

    Type Journal Article
    Author Shisei Tei
    Author Pascal L Faber
    Author Dietrich Lehmann
    Author Takuya Tsujiuchi
    Author Hiroaki Kumano
    Author Roberto D Pascual-Marqui
    Author Lorena R R Gianotti
    Author Kieko Kochi
    Abstract Many meditation exercises aim at increased awareness of ongoing experiences through sustained attention and at detachment, i.e., non-engaging observation of these ongoing experiences by the intent not to analyze, judge or expect anything. Long-term meditation practice is believed to generalize the ability of increased awareness and greater detachment into everyday life. We hypothesized that neuroplasticity effects of meditation (correlates of increased awareness and detachment) would be detectable in a no-task resting state. EEG recorded during resting was compared between Qigong meditators and controls. Using LORETA (low resolution electromagnetic tomography) to compute the intracerebral source locations, differences in brain activations between groups were found in the inhibitory delta EEG frequency band. In the meditators, appraisal systems were inhibited, while brain areas involved in the detection and integration of internal and external sensory information showed increased activation. This suggests that neuroplasticity effects of long-term meditation practice, subjectively described as increased awareness and greater detachment, are carried over into non-meditating states.
    Publication Brain Topography
    Volume 22
    Issue 3
    Pages 158-165
    Date Nov 2009
    Journal Abbr Brain Topogr
    DOI 10.1007/s10548-009-0107-4
    ISSN 1573-6792
    Short Title Meditators and non-meditators
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19653090
    Accessed Sat Sep 26 14:58:46 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19653090
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • pre

    Notes:

    • Many meditation exercises aim at increased awareness of ongoing experiences through sustained attention and at detachment, i.e., non-engaging observation of these ongoing experiences by the intent not to analyze, judge or expect anything. Long-term meditation practice is believed to generalize the ability of increased awareness and greater detachment into everyday life. We hypothesized that neuroplasticity effects of meditation (correlates of increased awareness and detachment) would be detectable in a no-task resting state. EEG recorded during resting was compared between Qigong meditators and controls. Using LORETA (low resolution electromagnetic tomography) to compute the intracerebral source locations, differences in brain activations between groups were found in the inhibitory delta EEG frequency band. In the meditators, appraisal systems were inhibited, while brain areas involved in the detection and integration of internal and external sensory information showed increased activation. This suggests that neuroplasticity effects of long-term meditation practice, subjectively described as increased awareness and greater detachment, are carried over into non-meditating states.

  • Age effects on attentional blink performance in meditation

    Type Journal Article
    Author Sara van Leeuwen
    Author Notger G Müller
    Author Lucia Melloni
    Abstract Here we explore whether mental training in the form of meditation can help to overcome age-related attentional decline. We compared performance on the attentional blink task between three populations: A group of long-term meditation practitioners within an older population, a control group of age-matched participants and a control group of young participants. Members of both control groups had never practiced meditation. Our results show that long-term meditation practice leads to a reduction of the attentional blink. Meditation practitioners taken from an older population showed a reduction in blink as compared to a control group taken from a younger population, whereas, the control group age-matched to the meditators' group revealed a blink that was comparatively larger and broader. Our results support the hypothesis that meditation practice can: (i) alter the efficiency with which attentional resources are distributed and (ii) help to overcome age-related attentional deficits in the temporal domain.
    Publication Consciousness and Cognition
    Volume 18
    Issue 3
    Pages 593-599
    Date Sep 2009
    Journal Abbr Conscious Cogn
    DOI 10.1016/j.concog.2009.05.001
    ISSN 1090-2376
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19515578
    Accessed Sat Sep 26 15:31:24 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19515578
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Here we explore whether mental training in the form of meditation can help to overcome age-related attentional decline. We compared performance on the attentional blink task between three populations: A group of long-term meditation practitioners within an older population, a control group of age-matched participants and a control group of young participants. Members of both control groups had never practiced meditation. Our results show that long-term meditation practice leads to a reduction of the attentional blink. Meditation practitioners taken from an older population showed a reduction in blink as compared to a control group taken from a younger population, whereas, the control group age-matched to the meditators’ group revealed a blink that was comparatively larger and broader. Our results support the hypothesis that meditation practice can: (i) alter the efficiency with which attentional resources are distributed and (ii) help to overcome age-related attentional deficits in the temporal domain.

  • Long-term meditation is associated with increased gray matter density in the brain stem

    Type Journal Article
    Author Peter Vestergaard-Poulsen
    Author Martijn van Beek
    Author Joshua Skewes
    Author Carsten R Bjarkam
    Author Michael Stubberup
    Author Jes Bertelsen
    Author Andreas Roepstorff
    Abstract Extensive practice involving sustained attention can lead to changes in brain structure. Here, we report evidence of structural differences in the lower brainstem of participants engaged in the long-term practice of meditation. Using magnetic resonance imaging, we observed higher gray matter density in lower brain stem regions of experienced meditators compared with age-matched nonmeditators. Our findings show that long-term practitioners of meditation have structural differences in brainstem regions concerned with cardiorespiratory control. This could account for some of the cardiorespiratory parasympathetic effects and traits, as well as the cognitive, emotional, and immunoreactive impact reported in several studies of different meditation practices.
    Publication Neuroreport
    Volume 20
    Issue 2
    Pages 170-174
    Date Jan 28, 2009
    Journal Abbr Neuroreport
    DOI 10.1097/WNR.0b013e328320012a
    ISSN 1473-558X
    URL http://www.ncbi.nlm.nih.gov/pubmed/19104459
    Accessed Mon Mar 28 18:18:24 2011
    Library Catalog NCBI PubMed
    Extra PMID: 19104459
    Date Added Thu Sep 29 09:06:18 2011
    Modified Thu Sep 29 09:06:18 2011

    Tags:

    • Brain Stem
    • Female
    • Humans
    • Linear Models
    • Magnetic Resonance Imaging
    • Male
    • Meditation
    • Middle Aged
    • Neuronal Plasticity
  • Long-term meditation is associated with increased gray matter density in the brain stem

    Type Journal Article
    Author Peter Vestergaard-Poulsen
    Author Martijn van Beek
    Author Joshua Skewes
    Author Carsten R Bjarkam
    Author Michael Stubberup
    Author Jes Bertelsen
    Author Andreas Roepstorff
    Abstract Extensive practice involving sustained attention can lead to changes in brain structure. Here, we report evidence of structural differences in the lower brainstem of participants engaged in the long-term practice of meditation. Using magnetic resonance imaging, we observed higher gray matter density in lower brain stem regions of experienced meditators compared with age-matched nonmeditators. Our findings show that long-term practitioners of meditation have structural differences in brainstem regions concerned with cardiorespiratory control. This could account for some of the cardiorespiratory parasympathetic effects and traits, as well as the cognitive, emotional, and immunoreactive impact reported in several studies of different meditation practices.
    Publication Neuroreport
    Volume 20
    Issue 2
    Pages 170-174
    Date Jan 28, 2009
    Journal Abbr Neuroreport
    DOI 10.1097/WNR.0b013e328320012a
    ISSN 1473-558X
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19104459
    Accessed Sat Sep 26 14:52:06 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19104459
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Brain Stem
    • Female
    • Humans
    • Linear Models
    • Magnetic Resonance Imaging
    • Male
    • Meditation
    • Middle Aged
    • Neuronal Plasticity

    Notes:

    • Extensive practice involving sustained attention can lead to changes in brain structure. Here, we report evidence of structural differences in the lower brainstem of participants engaged in the long-term practice of meditation. Using magnetic resonance imaging, we observed higher gray matter density in lower brain stem regions of experienced meditators compared with age-matched nonmeditators. Our findings show that long-term practitioners of meditation have structural differences in brainstem regions concerned with cardiorespiratory control. This could account for some of the cardiorespiratory parasympathetic effects and traits, as well as the cognitive, emotional, and immunoreactive impact reported in several studies of different meditation practices.

  • Do Mindfulness Meditation Participants Do Their Homework? And Does It Make a Difference? A Review of the Empirical Evidence

    Type Journal Article
    Author Lisa Christine Vettese
    Author Tony Toneatto
    Author Jonathan N. Stea
    Author Linda Nguyen
    Author Jenny Jing Wang
    Abstract Mindfulness-based interventions have been shown to alleviate symptoms of a wide range of physical and mental health conditions. Regular between-session practice of mindfulness meditation is among the key factors proposed to produce the therapeutic benefits of mindfulness-based programs. This article reviews the mindfulness intervention literature with a focus on the status of home practice research and the relationship of practice to mindfulness program outcomes. Of 98 studies reviewed, nearly one-quarter (N = 24) evaluated the associations between home practice and measures of clinical functioning, with just over half (N = 13) demonstrating at least partial support for the benefits of practice. These findings indicate a substantial disparity between what is espoused clinically and what is known empirically about the benefits of mindfulness practice. Improved methodologies for tracking and evaluating the effects of home practice are recommended.
    Publication Journal of Cognitive Psychotherapy
    Volume 23
    Pages 198-225
    Date August 2009
    DOI 10.1891/0889-8391.23.3.198
    Short Title Do Mindfulness Meditation Participants Do Their Homework?
    URL http://www.ingentaconnect.com/content/springer/jcogp/2009/00000023/00000003/art00003
    Accessed Sat Sep 26 17:00:31 2009
    Library Catalog IngentaConnect
    Date Added Thu Sep 29 09:06:02 2011
    Modified Thu Sep 29 09:06:02 2011

    Tags:

    • Homework
    • Mindfulness-Based Cognitive Therapy
    • Mindfulness-Based Stress Reduction
    • Practice
  • Cardiorespiratory phase synchronization during normal rest and inward-attention meditation

    Type Journal Article
    Author Shr-Da Wu
    Author Pei-Chen Lo
    Abstract The cardiac and respiratory systems can be viewed as two self-sustained oscillators with various interactions between them. In this study, the cardiorespiratory phase synchronization (CRPS) quantified by synchrogram was investigated to explore the phase synchronization between these two systems. The synchrogram scheme was applied to electrocardiogram (ECG) and respiration signals. Particular focus was the distinct cardiac-respiratory regulation phenomena intervened by inward-attention meditation and normal relaxation. Four synchronization parameters were measured: frequency ratio, lasting length, number of epochs, and total length. The results showed that normal rest resulted in much weaker CRPS. Statistical analysis reveals that the number of synchronous epochs and the total synchronization length significantly increase (p = 0.024 and 0.034 respectively) during meditation. Furthermore, a predominance of 4:1 and 5:1 rhythm-ratio synchronizations was observed during meditation. Consequently, this study concludes that CRPS can be enhanced during meditation, compared with normal relaxation, and reveals a predominance of specific frequency ratios.
    Publication International Journal of Cardiology
    Volume 141
    Issue 3
    Pages 325-328
    Date June 11, 2010
    DOI 10.1016/j.ijcard.2008.11.137
    ISSN 0167-5273
    Accessed Tue Jul 27 13:46:45 2010
    Library Catalog ScienceDirect
    Date Added Thu Sep 29 09:03:23 2011
    Modified Thu Sep 29 09:03:23 2011

    Tags:

    • Cardiorespiratory interaction
    • Cardiorespiratory phase synchronization (CRPS)
    • Inward-attention meditation
    • Self-sustained oscillator
    • Synchrogram
  • Functional Connectivity at Meditation State

    Type Journal Article
    Author C.W. Wu
    Author C.H. Hsieh
    Author C.W. Li
    Author J.H. Chen
    Abstract Introduction Meditation means a mental training practice for the meditators to strengthen attentional focus and achieve a tranquil state (Brefczynski-Lewis JA, 2007). The engagement of such process on experienced meditators was reported combining with the increase of attention and improvement of perception (Jha A, 2007 and Carter OL, 2005). However, mapping the brain functions during meditation is arduous for experimental designs since the normal meditation usually last for a long time, comparing to timing of traditional cognitive task design. Therefore, in this work we applied the resting-state fMRI analyses (Biswal B, 1995) on the comparison between normal resting conditions and traditional Chinese meditation states. Methods Eight healthy experienced mediators participated in the experiments on a 3T Bruker Medspec system. A typical gradient-echo EPI sequence was used to collect imagings for 21 minutes (630 measurements, TR=2s). Images were acquired on the whole cerebrum (24 slices) along the AC-PC line, with FOV of 256 mm, MTX of 64×64, and slice thickness of 4mm. At first, subjects were instructed to close their eyes and stayed in a relaxing resting status during the beginning of 9-minute scan. Subsequently, the subjects were asked to read mantra and prepared to perform meditation, which lasted for no longer than 3 minutes. Subsequently, the subjects remained at meditation for the rest of the scan time (not, vert, similar 9 min, as shown in fig. 1). Data were pre-processed with motion correction, detrending, and low-pass filtered (<0.1 Hz) using MATLAB, and then underwent spatial normalization (resampled to an isotropic resolution 3×3×3 mm3), smoothing (Gausian kernel = 6 mm) and statistical analyses by AFNI. Physiological noise and motion artifacts were regressed out during individual calculation of cross-correlation. Spherical seeds with 6 mm diameter were placed on the right primary motor cortex (M1) [36, −28, 54] and right middle frontal gyrus (MFG) [38, 28, 26] in the normalized MNI/Talairach space to observe the connectivity in sensori-motor and attentional networks, respectively. A group-level analysis of correlation maps was performed to reveal significant functional connectivity (p <10−4, cluster = 529 mm3). Results Fig.2 shows the group results of functional connectivity maps on both motor and attention networks, overlaid on an averaged anatomical image. With seeds placed on right M1, strong connections are observed in the supplementary motor area (SMA) and contralateral M1, formatting the structure of sensori-motor networks. However, such connection was suppressed, or even disappeared in some brain area during the meditation state, such as the contralateral M1. When putting seeds on the right MFG, only ipsilateral connections to precentral gyrus (PCG) and middle temporal gyrus (MTG) are explicit under the resting state; however, under the meditation state, the contralateral side of MFG, and MTG are aroused, showing the concentration during performing meditation practices. Conclusions Functional connectivity analysis was first time adopted in the research of meditation in the current work. Such experimental design is more reliable and feasible for meditators without interruption of experimental interests. In contrast to resting status of the same group, the functional connectivity of motor and attention networks was indeed modulated by the practice of meditation.
    Publication NeuroImage
    Volume 47
    Issue Supplement 1
    Pages S42
    Date July 2009
    DOI 10.1016/S1053-8119(09)70006-0
    ISSN 1053-8119
    URL http://www.sciencedirect.com.ezproxy.bu.edu/science/article/B6WNP-4X3PHYG-6/2/3e7feb6276eecd7ce199962b262e68dd
    Accessed Sat Sep 26 18:29:40 2009
    Library Catalog ScienceDirect
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Notes:

    • Introduction: Meditation means a mental training practice for the meditators to strengthen attentional focus and achieve a tranquil state (Brefczynski-Lewis JA, 2007). The engagement of such process on experienced meditators was reported combining with the increase of attention and improvement of perception (Jha A, 2007 and Carter OL, 2005). However, mapping the brain functions during meditation is arduous for experimental designs since the normal meditation usually last for a long time, comparing to timing of traditional cognitive task design. Therefore, in this work we applied the resting-state fMRI analyses (Biswal B, 1995) on the comparison between normal resting conditions and traditional Chinese meditation states. Methods: Eight healthy experienced mediators participated in the experiments on a 3T Bruker Medspec system. A typical gradient-echo EPI sequence was used to collect imagings for 21 minutes (630 measurements, TR=2s). Images were acquired on the whole cerebrum (24 slices) along the AC-PC line, with FOV of 256 mm, MTX of 64×64, and slice thickness of 4mm. At first, subjects were instructed to close their eyes and stayed in a relaxing resting status during the beginning of 9-minute scan. Subsequently, the subjects were asked to read mantra and prepared to perform meditation, which lasted for no longer than 3 minutes. Subsequently, the subjects remained at meditation for the rest of the scan time (not, vert, similar 9 min, as shown in fig. 1). Data were pre-processed with motion correction, detrending, and low-pass filtered (<0.1 Hz) using MATLAB, and then underwent spatial normalization (resampled to an isotropic resolution 3×3×3 mm3), smoothing (Gausian kernel = 6 mm) and statistical analyses by AFNI. Physiological noise and motion artifacts were regressed out during individual calculation of cross-correlation. Spherical seeds with 6 mm diameter were placed on the right primary motor cortex (M1) [36, −28, 54] and right middle frontal gyrus (MFG) [38, 28, 26] in the normalized MNI/Talairach space to observe the connectivity in sensori-motor and attentional networks, respectively. A group-level analysis of correlation maps was performed to reveal significant functional connectivity (p <10−4, cluster = 529 mm3). Results: Fig.2 shows the group results of functional connectivity maps on both motor and attention networks, overlaid on an averaged anatomical image. With seeds placed on right M1, strong connections are observed in the supplementary motor area (SMA) and contralateral M1, formatting the structure of sensori-motor networks. However, such connection was suppressed, or even disappeared in some brain area during the meditation state, such as the contralateral M1. When putting seeds on the right MFG, only ipsilateral connections to precentral gyrus (PCG) and middle temporal gyrus (MTG) are explicit under the resting state; however, under the meditation state, the contralateral side of MFG, and MTG are aroused, showing the concentration during performing meditation practices. Conclusions: Functional connectivity analysis was first time adopted in the research of meditation in the current work. Such experimental design is more reliable and feasible for meditators without interruption of experimental interests. In contrast to resting status of the same group, the functional connectivity of motor and attention networks was indeed modulated by the practice of meditation.

  • Does meditation enhance cognition and brain plasticity?

    Type Journal Article
    Author Glen L Xiong
    Author P Murali Doraiswamy
    Abstract Meditation practices have various health benefits including the possibility of preserving cognition and preventing dementia. While the mechanisms remain investigational, studies show that meditation may affect multiple pathways that could play a role in brain aging and mental fitness. For example, meditation may reduce stress-induced cortisol secretion and this could have neuroprotective effects potentially via elevating levels of brain derived neurotrophic factor (BDNF). Meditation may also potentially have beneficial effects on lipid profiles and lower oxidative stress, both of which could in turn reduce the risk for cerebrovascular disease and age-related neurodegeneration. Further, meditation may potentially strengthen neuronal circuits and enhance cognitive reserve capacity. These are the theoretical bases for how meditation might enhance longevity and optimal health. Evidence to support a neuroprotective effect comes from cognitive, electroencephalogram (EEG), and structural neuroimaging studies. In one cross-sectional study, meditation practitioners were found to have a lower age-related decline in thickness of specific cortical regions. However, the enthusiasm must be balanced by the inconsistency and preliminary nature of existing studies as well as the fact that meditation comprises a heterogeneous group of practices. Key future challenges include the isolation of a potential common element in the different meditation modalities, replication of existing findings in larger randomized trials, determining the correct "dose," studying whether findings from expert practitioners are generalizable to a wider population, and better control of the confounding genetic, dietary and lifestyle influences.
    Publication Annals of the New York Academy of Sciences
    Volume 1172
    Pages 63-69
    Date Aug 2009
    Journal Abbr Ann. N. Y. Acad. Sci
    DOI 10.1196/annals.1393.002
    ISSN 1749-6632
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19743551
    Accessed Sat Sep 26 15:40:12 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19743551
    Date Added Sat Oct 1 16:55:15 2011
    Modified Sat Oct 1 16:55:15 2011

    Tags:

    • Brain
    • Brain-Derived Neurotrophic Factor
    • Clinical Trials as Topic
    • Cognition
    • Electroencephalography
    • Humans
    • Meditation
    • Meta-Analysis as Topic
    • Models, Biological
    • Neurodegenerative Diseases
    • Neuronal Plasticity

    Notes:

    • Meditation practices have various health benefits including the possibility of preserving cognition and preventing dementia. While the mechanisms remain investigational, studies show that meditation may affect multiple pathways that could play a role in brain aging and mental fitness. For example, meditation may reduce stress-induced cortisol secretion and this could have neuroprotective effects potentially via elevating levels of brain derived neurotrophic factor (BDNF). Meditation may also potentially have beneficial effects on lipid profiles and lower oxidative stress, both of which could in turn reduce the risk for cerebrovascular disease and age-related neurodegeneration. Further, meditation may potentially strengthen neuronal circuits and enhance cognitive reserve capacity. These are the theoretical bases for how meditation might enhance longevity and optimal health. Evidence to support a neuroprotective effect comes from cognitive, electroencephalogram (EEG), and structural neuroimaging studies. In one cross-sectional study, meditation practitioners were found to have a lower age-related decline in thickness of specific cortical regions. However, the enthusiasm must be balanced by the inconsistency and preliminary nature of existing studies as well as the fact that meditation comprises a heterogeneous group of practices. Key future challenges include the isolation of a potential common element in the different meditation modalities, replication of existing findings in larger randomized trials, determining the correct “dose,” studying whether findings from expert practitioners are generalizable to a wider population, and better control of the confounding genetic, dietary and lifestyle influences.

  • The effect of mindfulness meditation on cough reflex sensitivity

    Type Journal Article
    Author E C Young
    Author C Brammer
    Author E Owen
    Author N Brown
    Author J Lowe
    Author C Johnson
    Author R Calam
    Author S Jones
    Author A Woodcock
    Author J A Smith
    Abstract BACKGROUND: Chronic cough is common, and medical treatment can be ineffective. Mindfulness is a psychological intervention that aims to teach moment-to-moment non-judgemental awareness of thoughts, feelings and sensations. METHOD: 30 healthy subjects and 30 patients with chronic cough were studied in two sequential trials. For both studies, cough reflex sensitivity to citric acid (C5) was measured on two occasions, with urge to cough rated following each inhalation; between challenges subjects were randomised to (1) no intervention, (2) mindfulness or (3) no intervention but modified cough challenge (subjects suppress coughing). For the healthy volunteers, measures were 1 h apart and mindfulness was practised for 15 min. For the patients with chronic cough measures were 1 week apart and mindfulness was practised daily for 30 min. RESULTS: In healthy volunteers, median change (interquartile range (IQR)) in cough reflex sensitivity (logC5) for no intervention, mindfulness and suppression was +1.0 (0.0 to +1.3), +2.0 (+1.0 to +3.0) and +3.0 (+2.8 to +3.0) doubling concentrations (p = 0.003); there were significant reductions for both mindfulness (p = 0.043) and suppression (p = 0.002) over no intervention. In patients with cough, median change (IQR) in logC5 for no intervention, mindfulness training and voluntary suppression was 0.0 (-1.0 to +1.0), +1.0 (-0.3 to +1.0) and +1.0 (+1.0 to +2.0) doubling concentrations (p = 0.046); there was a significant reduction for suppression (p = 0.02) but not mindfulness (p = 0.35). Urge to cough did not change after mindfulness compared with control in either healthy subjects (p = 0.33) or those with chronic cough (p = 0.47). CONCLUSION: Compared with control, mindfulness decreased cough reflex sensitivity in healthy volunteers, but did not alter cough threshold in patients with chronic cough. Both groups were able to suppress cough responses to citric acid inhalation.
    Publication Thorax
    Volume 64
    Issue 11
    Pages 993-998
    Date Nov 2009
    Journal Abbr Thorax
    DOI 10.1136/thx.2009.116723
    ISSN 1468-3296
    URL http://www.ncbi.nlm.nih.gov.ezproxy.bu.edu/pubmed/19679578
    Accessed Mon Nov 23 19:51:04 2009
    Library Catalog NCBI PubMed
    Extra PMID: 19679578
    Date Added Thu Sep 29 09:04:55 2011
    Modified Thu Sep 29 09:04:55 2011
  • Effects of brief and sham mindfulness meditation on mood and cardiovascular variables

    Type Journal Article
    Author Fadel Zeidan
    Author Susan K Johnson
    Author Nakia S Gordon
    Author Paula Goolkasian
    Abstract Abstract Objectives: Although long-term meditation has been found to reduce negative mood and cardiovascular variables, the effects of a brief mindfulness meditation intervention when compared to a sham mindfulness meditation intervention are relatively unknown. This experiment examined whether a 3-day (1-hour total) mindfulness or sham mindfulness meditation intervention would improve mood and cardiovascular variables when compared to a control group. Methods: Eighty-two (82) undergraduate students (34 males, 48 females), with no prior meditation experience, participated in three sessions that involved training in either mindfulness meditation, sham mindfulness meditation, or a control group. Heart rate, blood pressure, and psychologic variables (Profile of Mood States, State Anxiety Inventory) were assessed before and after the intervention. Results: The meditation intervention was more effective at reducing negative mood, depression, fatigue, confusion, and heart rate, when compared to the sham and control groups. Conclusions: These results indicate that brief meditation training has beneficial effects on mood and cardiovascular variables that go beyond the demand characteristics of a sham meditation intervention.
    Publication Journal of Alternative and Complementary Medicine (New York, N.Y.)
    Volume 16
    Issue 8
    Pages 867-873
    Date Aug 2010
    Journal Abbr J Altern Complement Med
    DOI 10.1089/acm.2009.0321
    ISSN 1557-7708
    URL http://www.ncbi.nlm.nih.gov/pubmed/20666590
    Extra PMID: 20666590
    Date Added Thu Sep 29 09:02:43 2011
    Modified Thu Sep 29 09:02:43 2011