|
Home
About Me 
Research
Publications
Mentors
Recognition
|
Sangha Mitra, Ph.D.
Senior Research Associate,
Dept of Molecular and Cell biology
Boston
University School of Medicine
The progression of technology and the effects
it has had on civilization has fascinated me, and generated within me a
profound interest in the Sciences. Over the past decades, biological and
biochemical advances have become important resource to industry and medicine,
as fields like genetics, medicinal chemistry, biomaterials and now bio-energy
are developing. Below is a brief summary of my research journey.
Currently, as a senior researcher in Prof. Phillips Robbin’s and Prof. John Samuelson’s research
group, Department of Molecular and Cell Biology, Boston University School of
Medicine, I am investigating important enzymes from Giardia (an intestinal pathogen) and identifying the cellular
pathway involved in activating the best drug against Giardia infection. On my second project, I am synthesizing the
complete glycan precursor in vivo
in Giardia.
In my prior role, as a research associate in the group led
by Prof. Sean Elliott, Dept.of Chemistry, Boston University,
I led projects that required expertise in molecular biology, biochemistry and
biophysical techniques. A key methodology applied in investigation was the
direct electrochemical method of protein film voltammetry. Specifically, I
probed the redox chemistry of enzymes involved in oxidative stress response,
such as thioredoxin and glutaredoxin.
I hold a Ph.D. in biochemistry from Utah State
University. Under the
supervision of Prof. Richard Holz, I investigated the mechanism of methionine
aminopeptidase and nitrile hydratase. During the fruitful time spent on my
doctoral research, I worked on techniques as far ranging as gene cloning
expression, mutagenesis, sequencing, protein purification, assay development
to ITC and EPR spectroscopy.
I hold a Master's degree in Chemistry from Indian Institute of Technology, New Delhi (IIT-Delhi).
IIT exposed me to many forms of chemistry - organic, inorganic, physical,
organo-metallic, immunology and biochemistry. My Masters thesis research
focused on developing and using solid-state fermentation in the production of
an enzyme using waste products.
I hold a Bachelor's degree in Chemistry from Gargi
College, University of Delhi.
Having been inspired to study chemistry with fervor, I was often encouraged
by my teachers to participate in various chemistry related colloquiums and
competitions. I was recognized with the best student award for achieving the
highest grades in the university in 1998.
Home
|