Our research
focuses on the development and use of novel label-free detection
methods based on surface plasmon resonance (SPR) spectroscopy.
Current projects are focused around the development of novel
label-free DNA microarray technologies. Areas of study
include: Electric
field effects at
interfaces: rapid mismatch discrimination by electric field
induced denaturation. DNA/protein interactions: screening methods
for anti-tumor aptamers as tumor targeting reagents. DNA/drug
interactions: kinetics of binding novel platinum anti-tumor drugs
with
oligonucleotides.