Jinghua YANG, Ph.D.
Surgical Oncology Laboratory
Clinic Proteomics Facilities
Boston, MA 02118
Tel: (617) 414-7075
Boston, MA 02130
Tel: (857) 364-5611
Current/former laboratory members:
Bingguan Chen (Lab Manager); John Cao
Zhou FEI, Visiting Scholar
Yong Liu, Postdoc
Yongzhan Nie, Yingjun Su, Fanmin Zhang, Haili Su
Dexin Zhang, Xiaoxing Luo, Meihong Chen, Koroush Kabir, Qingchuan Zhao, Jinghua Yang
Research project 1
We are studying the biological function of dsRNA and dsRNA-binding proteins. These include the dsRNA editing enzyme ADAR1, ADAR2 and ADAR3. ADAR1 is ubiquitously expressed particularly in immune organs; ADAR2 is found in all tissues but dominant in neuronal system; and ADAR3 is exclusively in the brain. Currently our interest is focused on the function of ADAR1 in viral infection/stress, and ADAR2 in traumatic stress.
Research project 2
Our laboratory is pleased
to provide facilities to investigators of
Research project 3
Another focus of our laboratory is to identify the tumor specific complement activator (tsCA). This factor is found to activate human complement to kill different tumor cells in vitro.
Jinghua on Tom’s birthday
The RNA group on Tom Maniatis’ 60th birthday
James Waston on Tom’s birthday