nf-kb.org

REAGENTS

Target genes of NF-kB

Cytokines/Chemokines and their modulators

Immunoreceptors

Proteins involved in antigen presentation

Cell adhesion molecules

Acute phase proteins

Stress response genes

Cell-surface receptors

Regulators of apoptosis

Growth factors, ligands and their modulators

Early response genes

Transcription factors and Regulators

Viruses

Enzymes

Miscellaneous

(*indicates that the gene has a kB site in the promoter but has not clearly been shown to be controlled by NF-kB; or the gene expression is associated with increased NF-kB activity but has not been shown to be a target directly)

Cytokines/Chemokines and their modulators


Gene	Function	Reference	Acc #	Human Gene Name
BAFF	B-cell Activating Factor	Moon & Park , 2007	NM_006573	TNFSF13B
BLIMP-1	B lymphocyte-induced maturation protein-1	Calame, 2008	NM_00198	BLIMP1 /PRDM1
CCL5	T-cell secreted factor	Wickremasinghe et al, 2004	NM_002985	CCL5
CCL15/Leukotactin/ SCYA15	Chemokine for cell attraction	Shin et al, 2005	NM_032965	CCL15
CCL17	Chemokine	Takegawa et al, 2008	NM_002987	CCL17
CCL19	Recruitment of naive T cells to dendritic cells	Pietila et al, 2007	NM_006274	CCL19
CCL20	Ligand of CC chemokine receptor 6	Lee et al, 2008; Battaglia et al, 2007	NM_004591	CCL20
CCL22	Epithelial cell chemokine at mucosa	Nakayama et al, 2004	NM_002990	CCL22
CCL23/SYA23	Monocyte chemokine	Shin et al, 2007	NM_005064	CCL23
CCL28	Chemokine for T-cell attraction	Ogawa et al, 2004	NM_148672	CCL28
CINC-1	Cytokine-induced neutrophil chemoattractant	Blackwell et al, 1994 Ohtsuka et al, 1996	NM_001511	CXCL1
*CXCL 11	Chemokine ligand for CXCR3	Tensen et al, 1999	NM_005409	CXCL11
Eotaxin	beta Chemokine, eosinphil-specific	Hein et al, 1997	NM_001565.	CXCL10
Fractalkine	TNF-induced chemokine	Ahn et al, 2004;Bhavsar et al, 2008	NP_002987	CXCL3
Gro alpha	Melanoma growth stimulating activity	Anisowicz et al, 1991	NM_001511	CXCL1
Gro beta	Chemokine	Anisowicz et al, 1991	AAP13104	GRO-beta
Gro gamma	Chemokine	Anisowicz et al, 1991	AAP13105.	GRO-gamma
Gro-1	Growth regulated oncogene; chemokine	Wood, 1995	NM_001511	CXCL1
*ICOS	Inducible co-stimulator	Haaning Anderson et al, 2003	NM_012092	ICOS
IFN-g	Interferon	Sica et al, 1992; Sica et al, 1997	NM_000619	IFNG
IL-1a	Interleukin-1a	Mori & Prager, 1996	NM_000575	IL1A
IL-1b	Interleukin-1b	Hiscott et al, 1993	NM_000576	IL1B
IL-1 receptor antagonist	Inhibitor of IL-1 activity	Smith et al, 1994	NM_173842	IL1RN
IL-2	Interleukin-2	Serfling et al, 1989; Hoyos et al, 1989; Lai et al, 1995	NM_000586	IL2
IL-6	Interleukin-6, inflammatory cytokine	Libermann & Baltimore, 1990; Shimizu et al, 1990;Son et al, 2008	NM_000600	IL6
IL-8	Interleukin-8, alpha-chemokine	Kunsch & Rosen, 1993; Kang et al., 2007	NM_000584	IL8
IL-9	Interleukin-9	Zhu et al, 1996; Chen et al, 2008	NM_000590	IL9
IL-10	Interleukin-10	Xu & Shu, 2002; Cao et al, 2006	NM_000572	IL10
IL-11	Interleukin-11	Bitko et al, 1997	NM_000641	IL11
IL-12B (p40)	Interleukin-12	Murphy et al, 1995	NM_002187	IL12B
IL-12A (p35)	Interleukin-12	Homma et al, 2007	NM_000882	IL12A
IL-13	Interleukin-13	Hinz et al, 2002	NM_002188	IL13
*IL-15	Interleukin-15	Azimi et al, 1998	NM_172174	IL15
IL-17	Interleukin-17	Shen et al, 2006	NM_002190	IL17
IL-23A (p19)	Interleukin-23 (p19 gene)	Carmody et al, 2006; Liu et al, 2007	NM_016584	IL23A
IL-27 (p28)	Interleukin-27 (p28 subunit)	Liu et al, 2007	NM_145659	IL27
EBI3/IL-27B	EBV-induced gene 3 (IL-27beta chain)	Poleganov et al, 2008	NM_005755	EBI3
beta-Interferon	Interferon	Hiscott et al, 1989;	NM_002176	IFNB1
beta-Interferon	Interferon	Lenardo et al, 1989	NM_002176	IFNB1
IP-10	alpha Chemokine	Ohmori & Hamilton, 1993; Yang et al, 2007	NM_002994	CXCL5
KC	alpha Chemokine	Ohmori et al, 1995	S79767	KC
IiGp1	Cytokine	Bunting et al, 2007	NM_021792	Iigp1
			NM_002994	CXCL5
*LIX (mouse); ENA-78 (CXCL5) and GCP-2 (CXCL6) (human)	LPS-induced CXC chemokines	Smith et al, 2002	NM_002993	CXCL6
Lymphotoxin a	TNF-like cytokine	Worm et al, 1998	NM_000595	LTA
Lymphotoxin b	Anchors TNF to cell surface	Kuprash et al, 1996	NM_002341	LTB
MCP-1/JE	Macrophage chemotactic protein, beta Chemokine	Ueda et al, 1994; 1997	NM_002982	CCL2

		Teferedegne et al, 2006; Xing & Remnick, 2007; Ishikado et al, 2009
MIG	Monokine induced by IFN-gamma	Bunting et al, 2007	NM_002416	CXCL9
MIP-1a,b	Macrophage inflammatory protein-1, b Chemokine	Grove & Plumb, 1993; Widmer et al, 1993	NM_002983	CCL3
			NM_002984	CCL4
aka (LAG-1)	Lymphocyte activation gene-1	Xu et al, 2002; Modi et al, 2001	NM_002984	CCL4
MIP-2	Macrophage inflammatory protein-2, b Chemokine	Widmer et al, 1993; Lee et al, 2005	NM_002090	CXCL3
MIP-3alpha/CCL20	Macrophage inflammatory protein-3a	Kwon et al, 2002; Tomimori et al, 2007	NM_004591	CCL20
*mob-1	A C-X-C chemokine	Varley et al, 2003	NM_001565	CXCL10
Neutrophil activating peptide-78	Activates neutrophils	Keates et al., 2001	NM_002994	CXCL5
RANTES	Regulated upon Activation Normal T lymphocyte Expressed and Secreted,b Chemokine	Moriuchi et al, 1997	NM_002985	CCL5
TCA3, T-cell activation gene 3	T-cell activation gene 3, beta chemokine	Oh & Metcalfe, 1994	NM_002981	CCL1
TNFalpha	Tumor necrosis factor alpha	Shakhov et al, 1990; Collart et al, 1990	NM_000594	TNF
TNFbeta	Tumor necrosis factor beta	Paul et al, 1990; Messer et al, 1990	NM_000595	LTA
TRAIL (aka Apo2 ligand)	Cytokine	Baetu et al, 2001; Matsuda et al, 2005	NM_003810	TNFSF10
TFF3 (Treefoil factor)	Peptide in response to gut irritation	Baus-Loncar et al, 2004	NM_003226	TFF3
VEGI	Vascular endothelial growth inhibitor	Xiao et al, 2005	NM_005118	TNFSF15

Immunoreceptors


Gene	Function	Reference	Access #	Human Gene Name
B7.1 (CD80)	Co-stimulation of T cells via CD28 binding	Fong et al, 1996; Zhao et al, 1996	NM_005191	CD80
BRL-1	B-cell homing receptor	Wolf et al, 1998	NM_001716	BLR1
CCR5	Chemokine receptor	Liu et al, 1998	NM_000579	CCR5
CCR7	Chemokine receptor	Hopken et al, 2002	NM_001838	CCR7
CXCR	Chemokine receptor	Maxwell et al, 2007	NM_000634	IL8RA
CXCR2	Chemokine receptor	Maxwell et al, 2007	NM_001557	IL8RB
CD137	TNF-like receptor	Kim et al, 2003	NM_001561	TNFRSF9
CD154	CD40 ligand	Srahna et al, 2001; Schubert et al, 2002; Pham et al, 2005	NM_000074	CD40LG
CD3gamma	T-cell marker	Willard-Gallo et al, 2005	NM_000073	CD3G
CD21	B-cell surface molecule	Debnath et al, 2007	NM_001006658	CR2
CD38	NAD to cADP ribose converting molecule	Kang et al, 2006; Tirumurugaan et al, 2008	NM_001775	CD38
CD40	TNF-receptor family member	Hinz et al, 2001	NM_001250	CD40
CD48	Antigen of stimulated lymphocytes	Klaman & Thorley-Lawson, 1995	NM_001778	CD48
CD83	T-cell development molecule	McKinsey et al, 2000; Berchtold et al, 2002	NM_004233	CD83
CD86	Dendritic cell development molecule	Zou & Hu, 2005	NM_175862	CD86
CD98	Membrane receptor, survival blood cells	Yan et al, 2006	NM_001012661	SLC3A2
CD134	TNF-like receptor	Tone et al, 2007	NM_003327	TNFRSF4
*F11-receptor	Ig-like receptor for platelet adhesion	Sobocki et al, 2005	NM_016946	F11R
FcRn	Neonatal receptor for IgG	Liu et al, 2007	NM_004107	FCGRT
Fc epsilon receptor II (CD23)	Receptor for IgE	Richards & Katz, 1997; Lu et al, 2006; Debnath et al, 2007	NM_002002	FCER2
HLA-G	Human leukocyte antigen-G	Langat et al., 2007	NM_002127	HLA-G
*ICOS	T-cell activation factor	Shilling et al., 2005	NM_012092	ICOS
IL-2 receptor a-chain	IL-2 receptor subunit	Ballard et al., 1988	NM_000417	IL2RA
Immunoglobulin Cgamma1	IgG heavy chain	Lin & Stavnezer, 1996	J00230	IGHG2
Immunoglobulin gamma1	IgG heavy chain	Dryer & Covey, 2005	J00228	IGHG1
Immunoglobulin gamma4	IgG heavy chain	Agresti & Vercelli, 2002	K01316	IGHG4
Immunoglobulin e heavy chain	IgE heavy chain	Iciek et al, 1997	J00222	IGHE
Immunoglobulin k light chain	Antibody light chain	Sen & Baltimore, 1986	J00241	IGKC
Invariant Chain I_I	Antigen presentation	Pessara & Koch, 1990
Kinin B1 Receptor	Cardiovascular homeostasis; inflammation	Merino et al, 2005	NM_000710	BDKRB1
MHC class I (H-2Kb)	Major histocompatibility antigen	Isra�l et al, 1989; Isra�l et al, 1989
MHC Class I HLA-B7	Major histocompatibility antigen	Johnson & Pober, 1994	NM_005514	HLA-B
b2 Microglobulin	Chaperone for MHC class I-like molecules	Isra�l et al, 1989; Isra�l et al, 1989; Gobin et al, 2002	NM_004048	B2M
Nod2	Intracellular pathogen recognition	Gutierrez et al, 2002	NM_022162	NOD2
Polymeric Ig receptor	Binds Ig	Schjerven et al, 2001	AJ276452	pIgR
PGRP-S	Peptidoglycan recognition protein-S	Lang et al, 2007	NM_005091	PGLYRP1
T-cell receptor b chain	T-cell receptor subunit	Jamieson et al, 1989; McMillan & SIkes, 2008	NG_001333	TCRB
T-cell receptor/CD3gamma	T-cell receptor subunit	Badran et al, 2002	NM_000073	CD3G
TLR-2	Toll-like receptor	Wang et al, 2001; Johnson & Tapping, 2007	NM_003264	TLR2
TLR9	Toll-like receptor	Takeshita et al, 2004	NM_017442	TLR9
*TNF-Receptor, p75/80 (CD120B)	High-affinity TNF receptor	Santee & Owen-Schaub, 1996	NM_001066	TNFRSF1B
TREM-1	Neutrophil/monocyte Ig receptor	Zeng et al, 2007	NM_018643	TREM1

Proteins involved in antigen presentation


Gene	Function	Reference	Acc #	Human Gene Name
Complement B	Activator of alternative complement pathway	Huang et al, 2002	NM_001710	CFB
Complement component 3	Component of complement pathway	Moon et al, 1999	NM_000064	C3
Complement Receptor 2	Complement receptor for B-cell response to Ag	Tolnay et al, 2002	NM_001006658	CR2
Proteasome Subunit LMP2	Subunit of 26S proteasome,cysteine protease	Wright et al, 1995; Marques et al, 2004	NM_002800	PSMB9
Peptide Transporter TAP1	Peptide transporter for ER	Wright et al, 1995; Marques et al, 2004	NM_000593	TAP1
Tapasin	MHC class I presentation and assembly	Herrmann et al, 2003	NM_003190	TAPBP

Cell adhesion molecules

Gene	Function	Reference	Acc #	Human Gene Name
CD44	Cell-surface receptor for hyaluronic acid	Hinz et al, 2002	NP_000601	CD44
DC-SIGN	Dendritic cell surface C-type lectin	Liu et al, 2003	NM_021155	CD209
ELAM-1 (CD62E, E-selectin)	E-selectin, endothelial cell leukocyte adhesion molecule	Whelan et al, 1991; Schindler & Baichwal, 1994	NM_000450	SELE
Endoglin	Endothelial cell membrane glycoprotein	Botella et al, 2002	NM_000118	ENG
Fibronectin	Extracellular attachment	Lee et al, 2002; Norton et al, 2004	NM_002026	FN1
ICAM-1	Intercellular adhesion molecule-1	van de Stolpe et al., 1994' Bunting et al, 2007	NM_000201	CD54
MadCAM-1	Mucosal addressin cell adhesion molecule	Takeuchi & Baichwal, 1995	NM_130760	MADCAM1
NCAM	Neural cell adhesion molecule	Simpson & Morris, 2000	NM_000615	NCAM
P-selectin	Platelet adhesion receptor	Pan & McEver, 1995	NM_003005	SELP
Tenascin-C	ECM protein controls cell attachment and migration, cell growth	Mettouchi et al, 1997	NM_002160	TNC
VCAM-1	Vascular cell adhesion molecule	Iademarco et al, 1992	NM_001078	VCAM1

Acute phase proteins


Gene	Function	Reference	Acc #	Human Gene Name
Angiotensinogen (Angiotensin II)	Angiotensin precursor, regulates blood pressure	Brasier et al, 1990; Ron et al, 1990	NM_000029	AGT
beta-defensin-2	Anti-microbial peptide	Diamond et al, 2000; Tsutsumi-Ishii & Nagaoka, 2002; Kao et al, 2008	AF040153	DEFB2
C4b binding protein	Complement binding protein	Moffat & Tack, 1992	NM_000715	C4BPA
Complement factor B	Complement factor	Nonaka & Huang, 1990	NM_001710	CFB
Complement factor C4	Activates extrinsic pathway of complement activation	Yu et al, 1989	NM_007293	C4A
C-reactive protein	Host defense protein	Zhang et al, 1995; Agrawal et al, 2003	NM_000567	CRP
Hepcidin	Acute phase protein	Liao et al, 2006	NM_021175	HAMP
Lipopolysaccharide binding protein	Binds to LPS receptor (CD14) with LPS	Schumann, 1995	NM_004139	LBP
Pentraxin PTX3	Pentraxin	Basile et al, 1997	NM_002852	PTX3
Serum amyloid A proteins (SAA1, SAA2, SAA3)	Serum components	Edbrooke et al, 1991; Li & Liao, 1991; Thorn & Whiteside, 2002; Son et al, 2004	NM_000331	SAA1
Serum amyloid A proteins (SAA1, SAA2, SAA3)	Serum components		NM_030754	SAA2
Serum amyloid A proteins (SAA1, SAA2, SAA3)	Serum components		S73444	SAA3
Tissue factor-1	Activates extrinsic pathway of complement activation	Mackman et al, 1991	NM_001993	F3
Urokinase-type plasminogen activator	Activates fibrinogen for fibrin clot lysis	Novak et al, 1991	NM_002658	PLAU

Stress response genes


Gene	Function	Reference	Acc #	Human Gene Name
*CYP2E1	Cytochrome p450	Abdel-Razak et al, 2004	NM_000773	CYP2E1
CYP2C11	Cytochrome p450	Morgan et al, 2002	X79081	CYP2C11
CYP7b	Cytochrome p450	Dulos et al, 2005	NM_004820	CYP7B1
COX-2	Cyclooxygenase, prostaglandin endoperoxide synthase	Yamamoto et al, 1995;Ackerman et al, 2007; Kaltschmidt et al, 2002	NM_000963	PTGS2
Ferritin H chain	Iron storage protein	Kwak et al, 1995	NM_002032	FTH1
HSP90-alpha	Heat shock protein	Ammirante et al, 2007	NM_001017963	HSP90AA1
*5-Lipoxygenase (guinea pig)	Arachidonic acid metabolic enzyme, leukotriene synthesis	Chopra et al, 1992	XM_001127464	ALOX5
12-Lipoxygenase	Arachidonic acid metabolic enzyme	Arakawa et al, 1995	NM_000697	ALOX12
Inducible NO-Synthase	NO synthesis	Geller et al, 1993	NM_000625	NOS2A
*MAP4K1	Activator of stress-induced protein kinase pathway	Carter et al, 2002	NM_001042600	MAP4K1
Cu/Zn SOD	Superoxide dismutase	Rojo et al, 2004	NM_000454	SOD1
SOD1	Manganese uperoxide dismutase	Das et al, 1995	NM_000454	SOD1
SOD2	Manganese superoxide dismutase	Xu et al, 1999; 2007	NM_000636	SOD2
*Mx1	Viral resistance gene	Gerardin et al, 2004	NM_002462	MX1
NAD(P)H quinone oxidoreductase (DT-diaphorase)	Bioreductive enzyme	Yao & O'Dwyer, 1995	NM_000903	NQO1
Phospholipase A2	Fatty acid metabolism	Morri et al, 1994	AF058921	PLA2
SEPS1	Involved in cytokine production	Gao et al, 2006	NM_018445	SELS

Cell-surface receptors

Gene	Function	Reference	Acc #	Human Gene Name
ABCA1	ATP-binding cassette transporter	Gerbod-Giannone et al, 2006	NM_005502	ABCA1
ABCC6	ATP-binding, multidrug resistance-associated protein 6 transporter	Jiang et al, 2005	NM_001171	ABCC6
A1 adenosine receptor	Pleiotropic physiological effects	Nie et al, 1998; Jhaveri et al, 2007	NM_000674	ADORA1
A2A	Adenosine receptor	Morello et al, 2006	NM_000675	ADORA2A
*ADAM19	Dendritic cell marker	Ehrnsperger et al, 2005	NM_023038	ADAM19
Amiloride-sensitive sodium channel	Sodium channel	Baines et al, 2002; Haddad, 2005	NM_001038	SCNN1A
*alpha2B-adrenergic receptor	adrenergic receptor	Cayla et al, 2004	NM_000682	ADRA2B
Bradykinin B1-Receptor	Pleiotropic physiological effects	Ni et al, 1998	NM_000710	BDKRB1
*CD23	Cell-surface molecule	Tinnell et al, 1998	NM_002002	FCER2/CD23
CD69	Lectin mainly on activated T cells	Lopez-Cabrera et al, 1995	NM_001781	C69
DOR	Delta opiod receptor	Chen et al, 2005, 2006	NM_000911	OPRD1
Epidermal Growth Factor Receptor	Receptor for EGF	Nishi et al, 2003; Thornburg & Raab-Traub, 2007	NM_005228	EGFR
ErbB2	EGF-like receptor	Kitamura et al, 2005	NM_001005862	ERBB2
Gal1 Receptor	Galanin receptor, neuroendocrine peptide	Lorimer et al, 1997	NM_002256	KISS1
Lox-1	Receptor for Oxidized low density lipoprotein	Nagase et al, 1998	NM_002543	OLR1
Ly49	Receptor on NK cells	Pascal et al, 2007	NM_006611	KLRA1
Mdr1	Multiple drug resistance mediator (P-glycoprotein)	Zhou & Kuo, 1997; Wang et al, 2007	NM_018849	ABCB4
Mu-opioid receptor	Opioid Receptor	Kraus et al, 2003	EU360599	OPRM1
mGlu2	Metabotropic glutamate receptor 2	Chiechio et al, 2006	NM_000839	GRM2
Neuropeptide Y-Y1 receptor	Pleiotropic physiological effects	Musso et al, 1997	NM_000909	NPY1R
*NMDA receptor subunit 2A (rat)	Neural receptor for N-methyl-D-aspartate	Richter et al, 2002	NM_000833	GRIN2A
*NMDA receptor subunit NR-1 (GRIN1 gene)	Subunit of neural receptor for N-methyl-D-aspartate	Begni et al, 2003	NM_021569	GRIN1
Oxytocin receptor	Oxytocin receptor	Terizidou et al, 2006	NM_000916	OXTR
PAF receptor 1	Platelet activator receptor	Mutoh et al, 1994	NM_000952	PTAFR
P-gp	P-glycoprotein-Drug resistance	Wang et al, 2007	NM_000927	ABCB1
RAGE- receptor for advanced glycation end products	Receptor for Advanced Glycation End products	Li & Schmidt, 1997	NM_001136	AGER

Regulators of apoptosis

Gene	Function	Reference	Acc #	Human Gene Name
ASC	Apoptosis-associated speck-like protein containing a CARD	Sun et al, 2007	NM_013258	PYCARD
Bax	Pro-apoptotic Bcl-2 homologue	Grimm et al, 2004	NM_004324	BAX
Bfl1/A1	Pro-survival Bcl-2 homologue	Grumont et al, 1999; Zong et al, 1999	NM_004049	BCL2A1
Bcl-xL	Pro-survival Bcl-2 homologue	Chen et al, 1999; Lee et al, 1999	NM_138578	BCL2L1
Bcl-2	Pro-survival factor	Catz & Johnson, 2001	NM_000633	BCL2
Bim	Pro-apoptotic Bcl-2 homolog	Wang et al, 2008	NM_138621	BCL2L11
B7-H1	Programmed cell death ligand 1	Lee et al, 2005	NM_014143	CD274
BNIP3	Hypoxia-inducible death factor	Baetz et al, 2005; Shaw et al, 2006	NM_004052	BNIP3
Caspase-11	Caspase	Schauvliege et al, 2002	NM_001225	CASP4
Nr13	Pro-survival Bcl-2 homologue	Lee et al, 1999
c-FLIP	Pro-survival factor	Kreuz et al, 2001	NM_003879	CFLAR
CD95 (Fas)	Pro-apoptotic receptor	Chan et al, 1999; Zhou et al, 2005; Singh et al, 2006	NM_000043	FAS
CIDEA	Cell death-inducing DFFA-like effector A	Pettersson et al, 2008	NP_001270.1; NP_938031.1	CIDEA
*Fas-associated phosphatase-1	Protein phosphatase	Irie et al, 2001	NM_006264	PTPN13
Fas-Ligand	Inducer of apoptosis	Matsui et al, 1998; Singh et al, 2006	NM_000639	FASLG
IAPs	Inhibitors of Apoptosis	You et al, 1997; Stehlik et al, 1998a, 1998b
IEX-1L	Immediate early gene	Wu et al, 1998	NM_052815	IER3
TRAF-1	TNF-receptor associated factor	Schwenzer et al, 1999	NM_005658	TRAF1
TRAF-2	TNF-receptor associated factor	Wang et al, 1998	NM_021138	TRAF2
*TRAF-2 binding protein (Carp)	TRAF2 binding protein	Chang et al, 2005	NM_052864	TIFA
XIAP	X-linked inhibitor of apoptosis	Turner et al, 2007	NM_001167	XIAP

Growth factors, ligands, and their modulators


Gene	Function	Reference	Acc #	Human Gene Name
Activin A	TGF-beta-like factor	Alexander et al, 2007	NM_002192	INHBA
Angiopoietin	Tie-2 receptor ligand	Scott et al, 2005	NM_001146	ANGPT1
BCAP	B-cell Adaptor for Phosphoinositide 3-kinase	Gupta et al, 2008	NM_152309	PI3KAP1
BDNF	Brain-derived neurotrophic factor	Saha et al, 2007	NM_001709	BDNF
BLyS	B-lymphocyte stimulator	Fu et al, 2006	NM_006573	TNFSF13B
BLNK	B-cell linker	Gupta et al, 2008	NM_013314	BLNK
BMP-2	Bone Morphogenic Protein-2	Feng et al, 2003; Fukui et al, 2006	NM_001200	BMP2
BMP-4	Bone Morphogenic Protein-4	Zhu et al, 2007	NM_001202	BMP4
CGRP	Calcitonin gene-related peptide	Bowen et al, 2005	NM_000728	CALCB
FGF8	Fibroblast Growth Factor 8	Armstrong et al, 2006	NM_006119	FGF8
FLRG	Follistatin-related gene	Bartholin et al, 2007	NM_005860	FSTL3
G-CSF	Granulocyte Colony Stimulating Factor	Nishizawa & Nagata, 1990	NM_000759	CSF3
GM-CSF	Granulocyte Macrophage Colony Stimulating Factor	Schreck & Baeuerle, 1990; Bunting et al, 2007	NM_000758	CSF2
*HGF/SF	Hepatocyte growth factor/scatter factor	Harrison & Farzaneh, 2000	NM_000601	HGF
EPO	Erythropoietin	Figueroa et al, 2002	NM_000799	EPO
*IGFBP-1	Insulin-like growth factor binding protein-1	Lang et al, 1999	NM_001013029	IGFBP1
IGFBP-2	Insulin-like growth factor binding protein-2	Cazals et al, 1999<

Acc #