|
References Relevant publications listed by the last name of
the first author.
Tabanca N, Ma G, Pasco DS, Bedir E, Kirimer N, Baser KH, Khan IA and Khan SI (2007) Effect of essential oils and isolated compounds from Pimpinella species on NF-kB: a target for antiinflammatory therapy. Phytotherapy Research in press Tabary O, Boncoeur E, de Martin R, Pepperkok R,
Clement A, Schultz D and Jacquot J (2006) Calcium-dependent regulation of NF-kB
activation in cystic fibrosis airway epithelial cells. Cellular Signaling 18
652-660 Tabary O, Escotte S,
Couetil JP, Hubert D, Dusser D, Puchelle E and Jacquot J (2002) Relationship
between IkBa deficiency, NFkB activity and interleukin-8 production in CF
human airway epithelial cells. Pflugers Arch 443 Suppl 1 S40-S44 Tabary O, Muselet C, Miesch
MC, Yvin JC, Clement A and Jacquot J (2003) Reduction of chemokine IL-8 and
RANTES expression in human bronchial epithelial cells by a sea-water derived
saline through inhibited nuclear factor-kB activation. Biochemical and
Biophysical Research Communications 309 310-316 Tabruyn SP and Griffioen AW (2008) NF-kB: a new player in angiostatic therapy. Angiogenesis in press Tabruyn SP, Sabatel C, Nguyen NQ, Verhaeghe C, Castermans K, Malvaux L, Griffioen AW, Martial JA and Struman I (2007) The angiostatic 16K human prolactin overcomes endothelial cell anergy and promotes leukocyte infiltration via NF-kB activation. Molecular Endocrinology in press Tabruyn SP, Sorlet CM, Rentier-Delrue F, Bours V, Weiner RI, Martial JA and Struman I (2003) The antiangiogenic factor 16K hPRL induces
caspases-dependent apoptosis by a mechanism that requires activation of NF-kB.
Molecular Endocrinology 17 1815-1823 Tacke F, Luedde T and Trautwein C (2008) Inflammatory pathways in liver homeostasis and liver injury. Clincal Reviews in Allergy and Immunology in press Tacker DH, Herzog NK and Okorodudu AO (2006) Cocaethylene affects human microvascular endothelial cell p38 mitogen-activated protein kinase activation and nuclear factor-kB DNA-binding activity. Clinical Chemistry 52 1926-1933
Taddeo B, Luo TR, Zhang W and Roizman B (2003) Activation of NF-kB in cells
productively infected with HSV-1 depends on activated protein kinase R and
plays no apparent role in blocking apoptosis. Proceedings of the National
Academy of Sciences USA 100 12408-12413 Tagawa H, Suguro M, Tsuzuki S, Matsuo K, Karnan S, Ohsima K, Okamoto M, Morishima Y, Nakamura S and Seto M (2005) Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphoma. Blood 106 1777-1777
Taganov KD, Boldin MP, Chang KJ and
Baltilmore D (20060 NF-kB-dependent induction of microRNA miR-146, an
inhibitor targeted to signaling proteins of innate immune responses. Taggart CC, Cryan SA, Weldon S, Gibbons A, Greene CM, Kelly E, Low TB, O'Neill SJ and McElvaney NG (2005) Secretory leucoprotease inhibitor binds to NF-kB binding sites in monocytes and inhibits p65 binding. Journal of Experimental Medicine 202 1659-1668
Tago K, Funakoshi M,
Mano H, Yanagisawa K, Hayakawa M, Kuroiwa K, Iwahana H, Kasahara T and
Tominaga S (2001) Presence of a genistein-responsive inhibitory mechanism on
interleukin-1alpha-induced NF-kB activation. European Journal of Biochemistry
268 6526-6533 Tahan F, Jazrai E, Moodley T< Rovati GE and Adcock IM (20080 Montelukast inhibits tumour necrosis factor-alpha-mediated interleukin-8 expression through inhibition of nuclear factor-kB p65-associated histone acetyltransferase activity. Clinical and Experimental Allergy in press
Tahepold P, Vaage J, Starkopf J and Valen G (2003) Hyperoxia elicits
myocardial protection through a nuclear factor kB-dependent mechanism in the
rat heart. Journal of Thoracic and Cardiovascular Surgery 125 650-660 Taher YA, van Esch BC, Hofman GA, Henricks PA and van Oosterhout AJ (2008) 1a,25-Dihydroxyvitamin D3 potentiates the beneficial effects of allergen immunotherapy in a mouse model of allergic asthma: role for IL-10 and TGF-beta. Journal of Immunology 180 5211-5221 Tahera Y, Meltser I, Johansson P, Bian Z, Stierna P, Hansson AC and Canlon B (2006) NF-kB mediated glucocorticoid response in the inner ear after acoustic trauma. Journal of Neuroscience Research 83 1066-1076 Tahera Y, Meltser I, Johansson P and Canlon B (2006) Restraint stress modulates glucocorticoid receptors and nuclear factor kB in the cochlea. Neuroreport 17 879-882 Tahera Y, Meltser L, Johansson P, Hansson AC and Canlon B (2006) Glucocorticoid receptor and NFkB interactions in restraint stress mediated protection against acoustic trauma. Endocrinology 147 4430-4437 Taherzadeh M, Fradette C, Bleau AM, Jomphe C, Trudeau LE and du Souich P (2005) The 21-aminosteroid U74389G prevents the down-regulation and decrease in activity of CYP1A1, 1A2 and 3A6 induced by an inflammatory reaction. Biochemical Pharmacology 71 366-376 Tahk S, Liu B, Chernishof V, Wond KA, Wu H and Shuai K (2007) Control of specificity and magnitude of NF-kB and STAT1-mediated gene activation through PIASy and PIAS1 cooperation. Proceedings of the National Academy of Sciences USA in press Tai AK, Zhou
G, Chau K and Ono SJ (1999) Cis-element dependence and occupancy of the human
invariant chain promoter in CIITA-dependent and -independent transcription.
Molecular Immunology 36 447-460 Tai DI, Tsai
SL, Chang YH, Huang SN, Chen TC, Chang KS and Liaw YF (2000) Constitutive
activation of nuclear factor kB in hepatocellular carcinoma. Cancer 89 2274-2281 Tai DI, Tsai SL, Chen YM, Chuang YL, Peng CY, Sheen IS, Yeh
CT, Chang KS, Huang SN, Kuo GC and Liaw YF (2000) Activation of nuclear
factor kB in hepatitis C virus infection: implications for pathogenesis and
hepatocarcinogenesis. Hepatology 31 656-664 Tai KY, Shieh YS, Lee CS, Shiah SG and Wu CW (2008) Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-kB and Brg-1. Oncogene in press Tai YT, Catley
LP, Mitsiades CS, Burger R, Podar K, Shringpaure R, Hideshima T, Chauhan D,
Hamasaki M, Ishitsuka K, Richardson P, Treon SP, Munshi NC and Anderson KC
(2004) Mechanisms by which SGN-40, a humanized anti-CD40 antibody, induces
cytotoxicity in human multiple myeloma cells: clinical implications. Cancer
Research 64 2846-2852 Taima K, Takanashi S, Okumura K, Imaizumi T, Kumagai M, Ishikawa A, Yoshida H,
Satoh K and Fujita T (2005) Double-stranded RNA stimulates the expression of
monocyte chemoattractant protein-1 in BEAS-2B bronchial epithelial cells.
Experimental Lung Research 31 361-375 Tai YT, Li X, Breitkreutz I, Song W, Neri P, Catley L, Podar K, Hideshima T, Chanhan D, Raje N, Schlossman R, Richardson P, Munshi NC and Anderson KC (2006) Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment. Cancer Research 66 6675-6682 Tai YT, Li X, Tong X, Santos D, Otsuki T, Catley L, Tournilhac O, Podar K, Hideshima T, Scholossman T, Richardson P, Munshi NC, Lugman M and Anderson KC (2005) Human anti-CD40 antagonist antibody triggers significant antitumor activity against human multiple myeloma. Cancer Research 65 5898-5906 Tai
YT, Podar K, Mitsiades N, Lin B, Mitsiades C, Gupta D, Akiyama M, Catley L,
Hideshima T, Munshi NC, Treon SP and Anderson KC (2003) CD40 induces human
multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kB
signaling. Blood 101 2762-2769 Tak PP, Gerlag DM, Aupperle KR, van de Geest DA, Overbeek M, Bennett BL, Boyle DL, Manning AM and Firestein GS (2001) Inhibitor of nuclear factor kB kinase beta is a key regulator of synovial inflammation. Arthritis & Rheumatism 44 1897-1907
Takacs P,
Kauma SW, Sholley MM, Walsh SW, Dinsmoor MJ and Green K (2001) Increased
circulating lipid peroxides in severe preeclampsia activate NF-kB and
upregulate ICAM-1 in vascular endothelial cells. FASEB Journal 15 279-281 Takada I, Suzawa M, Matsumoto K and Kato S (2007) Suppression of PPAR-g transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts. Annals of the New York Academy of Sciences in press Takada N, Sanda T, Okamoto H, Yang JP, Asamitsu K, Sarol L, Kimura G,
Uranishi H, Tetsuka T and Okamoto T (2002) RelA-associated inhibitor blocks
transcription of human immunodeficiency virus type 1 by inhibiting NF-kB and
Sp1 actions. Journal of Virology 76 8019-8030 Takada
Y and Aggarwal BB (2003) Genetic deletion of the TNF receptor p60 or p80
sensitizes macrophages to lipopolysaccharide-induced nuclear factor-kB,
mitogen-activated protein kinases and apoptosis. Journal of Biological
Chemistry 278 23390-23397 Takada Y, Bhardwaj A, Potdar P and Aggarwal BB (2004) Nonsteroidal
anti-inflammatory agents differ in their ability to suppress NF-kappaB
activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and
abrogation of tumor cell proliferation. Oncogene 23 9247-9258 Takada Y, Khuri F and Aggarwal BB (2004) Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kB-regulated gene expression and upregulation of apoptosis. Journal of Biological Chemistry 279 26287-26299 Takada Y, Kobayashi Y and Aggarwal BB (2005) Evodiamine abolishes constitutive and inducible NF-kB activation by inhibiting IkBa kinase activation, thereby suppressing NF-kB-regulated antiapoptotic and metastatic gene expression, upregulating apoptosis, and inhibiting invasion. Journal of Biological Chemistry 280 17203-17212 Takada Y,
Mukhopadhyay A, Kundu GC, Mahabeleshwar GH, Singh S and Aggarwal BB
(2003) Hydrogen peroxide activates NF-kB through tyrosine phosphorylation of
IkBa and serine phosphorylation of P65: evidence for the involvement of IkBa
kinase and Syk protein tyrosine kinase. Journal of Biological Chemistry 278
24233-24241 Takada Y, Sethi G, Sung B and Aggarwal BB (2008) Flavopiridol suppresses TNF-induced activation of AP-1, JNK, p38 MAPK, p44/p42 MAPK and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells. Molecular Pharmacology in press Takada Y, Singh S and Aggarwal BB (2004) Identification of a p65 peptide that selectively inhibits NF-kB activation induced by various inflammatory stimuli and its role in downregulation of NF-kB-mediated gene expression and upregulation of apoptosis. Journal of Biological Chemistry 279 15096-15104 Takada Y, Sung B, Sethi G, Chaturvedi MM and Aggarwal BB (2007) Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages. Biochemical Pharmacology in press Takaesu G,
Kishida S, Hiyama A, Yamaguchi K, Shibuya H, Irie K, Ninomiya-Tsuji J and Matsumoto K (2000) TAB2, a novel adaptor protein, mediates activation
of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction
pathway. Molecular Cell 5
649-658 Takagi H, Sanada T, Minoda Y and Yoshimura A (2004) Regulation of cytokine and toll-like receptor signaling by SOCS family genes [Article in Japanese]. Nippon Rinsho 62 2189-2196 Takagi K and Kudo Z (2008) Bone marrow stromal cell lines having high potential for osteoclast-supporting activity express PPARgamma1 and show high potential for differentiation into adipocytes. Journal of Bone Mineral and Metabolism 26 13-23 Takagi T, Naito Y, Tomatsuri N, Handa O, Ichikawa H, Yoshida N and Yoshikawa T
(2002) Pioglitazone, a PPAR-gamma ligand, provides protection from dextran
sulfate sodium-induced colitis in mice in association with inhibition of the
NF-kB-cytokine cascade. Redox Reports 7 283-289 Takahashi H, Feuerhake F, Monti S, Kutok JL, Aster JC and Shipp MA (2006) Lack of IKBA coding region mutations in primary mediastinal large B-cell lymphoma and the host response subtype of diffuse large B-cell lymphoma. Blood 107 844-845 Takahashi H, Funahashi H, Sawai H, Matsuo Y, Yamamoto M, Ikada Y, Takeyama H and Manabe T (2007) Synthetic serine protease inhibitor, gabexate mesilate, prevents nuclear factor-kB activation and increases TNF-a-mediated apoptosis in human pancreatic cancer cells. Dig Dis Sci in press
Takahashi H, Funahashi H, Sawai H, Sakamoto M, Matsuo Y, Yamamoto M, Okada Y,
Hayakawa T and Manabe T (2004) Glial cell line-derived neurotrophic factor
enhances nuclear factor-kB activity and invasive potential in human pancreatic
cancer cells. Pancreas 29 22-27 Takahashi I, Watanabe H, Murakami M, Ohba T, Radovanovic M, Ono K, Iijima T and Ito H (2007) Involvement of transient receptor potential canonical 1 (TRPC1) in angiotensin II-induced vascular smooth muscle cell hypertrophy. Atherosclerosis in press Takahashi K, Kawai T, Kumar H, Sato S, Yonehara S and Akira S (2006) Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA. Journal of Immunology 176 4520-4524
Takahashi M, Mutoh M, Shoji Y, Kamanaka Y, Naka M, Maruyama T, Sugimura T and
Wakabayashi K (2003) Transfection of K-ras(Asp12) cDNA markedly elevates
IL-1beta- and lipopolysaccharide-mediated inducible nitric oxide synthase
expression in rat intestinal epithelial cells. Oncogene 22 7667-7676 Takahashi N, Kobayashi S, Kajino S, Imai K, Tomoda K, Shimizu S and Okamoto T (2005) Inhibition of the 53BP2S-mediated apoptosis by nuclear factor kB and Bcl-2 family proteins. Genes Cells 10 803-811
Takahashi N, Tetsuka T, Uranishi H and Okamoto T
(2002) Inhibition of the NF-kB transcriptional activity by protein kinase A.
European Journal of Biochemistry 269 4559-4565 Takahashi N,
Udagawa N and Suda T (1999) A new member of tumor necrosis factor ligand
family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and
function. Biochemical and Biophysical Research Communications 256 449-455 Takahshi N, van Kilsdonk JW, Ostendorf B, Smeets R, Bruggeman SW, Alonso A, van de Loo F, Schneider M, van den Berg WB and Swart GW (2008) Tumor marker nucleoporin 88kDa regulates nucleocytoplasmic transport of NF-kB. Biochemical and Biophysical Research Communications in press Takahashi R, Sonoda Y, Ichikawa D, Yoshida N, Eriko AY and Tadashi K (2006) Focal adhesion kinase determines the fate of death or survival of cells in response to TNFalpha in the presence of actinomycin D. Biochimica et Biophysica Acta in press Takahashi S, Fujita T and Yamamoto A (2001) Role of nuclear factor-kB in gastric ulcer healing in rats. American Journal of Physiology: Gastrointestinal and Liver Physiology 280 G1296-G1304 Takahashi S, Harigae H, Ishii KK, Inomata M, Fujiwara T, Yokoyama H, Ishizawa K, Kameoka J, Licht JD, Sasaki T and Kaku M (2005) Over-expression of Flt3 induces NF-kB pathway and increases the expression of IL-6. Leukemia Research 29 893-899 Takahashi S, McConnell MJ, Harigae H, Kaku M, Sasaki T, Melnick AM and Licht JD (2004) The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT. Blood 103 4650-4658 Takahashi T,
Tanaka M, Inazawa J, Abe T, Suda T and Nagata S (1994) Human Fas ligand: gene
structure, chromosomal localization and species specificity. International
Immunology 6 1567-1574
Takahashi Y, Isuzugawa K, Murase Y, Imai M, Yamamoto S, Iizuka M, Akira S, Bahr GM, Momotani E, Hori M, Ozaki H and Imakawa K (2006) Up-regulation of NOD1 and NOD2 through TLR4 and TNF-a in LPS-treated murine macrophages. Journal of Veterinary Medical Science 68 471-478 Takahashi
Y, Tanaka Y, Yamashita A, Koyanagi Y, Nakamura M and Yamamoto N (2001) OX40
stimulation by gp34/OX40 ligand enhances productive human immunodeficiency
virus type 1 infection. Journal of Virology 75 6748-6757 Takahra T, Smart DE, Oakley F and Mann DA (2004) Induction of myofibroblast MMP-9 transcription in three-dimensional collagen I gel cultures: regulation by NF-kB, AP-1 and Sp1. International Journal of Biochemistry and Cell Biology 36 353-363 Takaishi K,
Ohtsuka T, Tsuneyoshi S, Maehara N, Harada M, Yoshida H, Watanabe K and
Tsurufuji S (2000) Inhibition of the production of rat cytokine-induced
neutrophil chemoattractant (CINC)-1, a member of the interleukin-8 family, by
adenovirus-mediated overexpression of IkBa. Journal of Biochemistry (Tokyo)
127 511-516 Takami M, Kim N, Rho J and Choi Y @002) Stimulation by tol-like receptors
inhibits osteoclasts differentiation. Journal of Immunology 169 1516-1523 Takami M, Woo
JT and Nagai K (1999) Osteoblastic cells induce fusion and activation of
osteoclasts through a mechanism independent of macrophage-colony-stimulating
factor production. Cell and Tissue Research 298 327-334 Takami Y, Nakagami H, Morishita R, Katsuya T, Cui TX, Saito Y, Hayashi H, Kikuchi Y, Nishikawa T, Baba Y, Yasuda O, Rakugi H, Ogihara T and Kaneda Y (2007) Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kB activation. Arteriosclerosis, Thrombosis, and Vascular Biology in press Takami Y, Nakagami H, Morishita R, Katsuya T, Hayashi H, Mori M, Koriyama H, Baba Y, Yasuda O, Rakugi H, Ogihara T and Kaneda Y (2008) Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells. American Journal of Pathology in press Takamoto M, Tsuji K, Yamashita T, Sasaki H, Yano T, Taketani Y, Komori T, Nifuji A and Noda M (2003) Hedgehog signaling enhances core-binding factor a1 and receptor activator of nuclear factor-kappaB ligand (RANKL) gene expression in chondrocytes. Journal of Endocrinology 177 413-421 Takamune Y, Ikebe T, Nagano O and Shinohara M (2007) Involvement of NF-kB-mediated maturation of ADAM-17 in the invasion of oral squamous cell carcinoma. Biochemical and Biophysical Research Communications inpress Takamura K,
Nasuhara Y, Kobayashi M, Betsuyaku T, Tanino Y, Kinoshita I, Yamaguchi E,
Matsukura S, Schleimer RP and Nishimura M (2004) Retinoic acid inhibits
interleukin-4-induced eotaxin production in a human bronchial epithelial cell
line. American Journal of Physiology: Lung Cell and Molecular Physiology 286 L777-L785 Takano
H, Inoue K, Yanagisawa R, Sato M, Shimada A, Morita T, Sawada M, Nakamura K,
Sanbongi C nad Yoshikawa T (2004) Protective role of metallothionein in acute
lung injury induced by bacterial endotoxin. Thorax 59 1057-1062 Takao T, Kumagai C, Hisakawa N, Matsumoto R and Hashimoto K (2005) Effect of 17beta-estradiol on tumor necrosis factor-alpha-induced cytotoxicity in the human peripheral T lymphocytes. Journal of Endocrinology 184 191-197 Takaoka M,
Ohkita M and Matsumura Y (2003) Pathophysiological
role of proteasome-dependent proteolytic pathway in endothelin-1-related
cardiovascular diseases. Current Vascular Pharmacology 1 19-26 Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y and Yondea Y (2007) Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid. European Journal of Pharmacology in press Takase O, Hirahashi J, Takayanagi A, Chikaraishi A, Marumo T, Ozawa Y, Hayashi
M, Shimizu N and Saruta T (2003) Gene transfer of truncated IkBa prevents
tubulointerstitial injury. Kidney International 63 501-513 Takase O, Marumo T, Imai N, Hirahashi J, Takayanagi A, Hishikawa K, Hayashi M, Shimizu H, Fujita T and Saruta T (2005) NF-kB-dependent increase in intrarenal angiotensin II induced by proteinuria. Kidney International 68 464-473 Takase O, Minto AW, Puri TS, Cunningham PN, Jacob A, Hayashi M and QUigg RJ (2007) Inhibition of NF-kB-dependent Bcl-xL expression by clusterin promotes albumin-induced tubular cell apoptosis. Kidney International in press Takashiba S,
Van Dyke TE, Amar S, Murayama Y, Soskolne AW and Shapira L (1999)
Differentiation of monocytes to macrophages primes cells for lipopolysaccharide
stimulation via accumulation of cytoplasmic nuclear factor kB. Infection and
Immunity 67 5573-5578 Takata
H, Tomizawa K, Matsushita M and Matsui H (2004) 2-methoxyestradiol enhances
p53 protein transduction therapy-associated inhibition of the proliferation of
oral cancer cells through the suppression of NFkB activity. Acta Med Okayama
58 181-187 Takatsuna H, Kato
H, Gohda J, Akiyama T, Moriya A, Okamoto Y, Yamagata Y,
Otsuka M, Umezawa K, Semba K and Inoue JI (2003) Identification of TIFA as an
adapter protein that links TRAF6 to IRAK-1 in IL-1 receptor signaling. Journal
of Biological Chemistry 278 12144-12150
Takayanagi H (2005) GeneChip analysis for osteoimmunology. Nihon Rinsho Meneki Gakkai Kaishi 28 79-85
Takayanagi H (2005) Osteoimmunological insight into bone damage in rheumatoid arthritis. Modern Rheumatology 15 225-231
Takayanagi H (2007) Osteoclast differentiation and activation [Article in Japanese]. Clinical Calcium 17 484-492
Takayanagi H, Kim S, Matsuo K, Suzuki H, Suzuki T, Sato K, Yokochi T, Oda H, Nakamura K, Ida N, Wagner EF and Taniguchi T (2002) RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature 416 744-749 Takayanagi H, Kim
S and Taniguchi T (2002) Signaling crosstalk between RANKL and interferons in
osteoclast differentiation. Arthritis Research 4 227-232
Takeda K,
Takuchi O, Tsujimura T, Itami S, Adachi S, Kawai T, Sanjo H, Yoshikawa K,
Terada N and Akira S (1999) Limb and skin abnormalities in mice lacking IKKa.
Science 284 313-316 Takegawa S, Jin Z, Nakayama T, Oyama T, Hieshima K, Nagakubo D, Shirakawa AK, Tsuzuki T, Nakamura S and Yoshie O (2008) Expression of CCL17 and CCL22 by latent membrane protein 1-positive tumor cells in age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorder. Cancer Science 99 296-302 Takehana K, Konishi A, Oonuki A,
Noguchi M, Fujita K, Iino Y and Kobayashi T (2002) APC0576, a novel inhibitor
of NF-kB-dependent gene activation, prevents pro-inflammatory
cytokine-induced chemokine production in human endothelial cells. Biochemical
and Biophysical Research Communications 293 945-952 Takei H, Baba Y, Hisatsune A, Katsuki H, Miyata T, Yokomizo K and Isohama Y (2008) Glycyrrhizin inhibits IL-8 production and NF-kB activity in lung epithelial cells, but not through glucocorticoid receptors. Journal of Pharmacological Sciences in press Takei Y, Laskey R (2007) Tumor necrosis factor alpha regulates responses to nerve growth factor, promoting neural cell survival but suppressing differentiation of neuroblastoma cells. Molecular Biology of the Cell in press Takemoto
M, Shimamoto T, Isegawa Y and Yamanishi K (2001) The R3 region, one of three
major repetitive regions of human herpesvirus 6, is a strong enhancer of
immediate-early gene U95. Journal of Virology 75 10149-10160 Takemoto Y,
Yoshiyama M, Takeuchi K, Omura T, Komatsu R, Izumi Y, Kim S and Yoshikawa J
(1999) Increased JNK, AP-1 and NF-kB DNA binding activities in
isoproterenol-induced cardiac remodeling. Journal of Molecular
and Cellular Cardiology 31 2017-2030 Takenouchi-Ohkubo N, Takahashi T, Tsuchiya M, Mestecky J,
Moldoveanu Z and Moro I (2000) Role of nuclear factor-kappaB in the
expression by tumor necrosis factor-alpha of the human polymeric
immunoglobulin receptor (plgR) gene. Immunogenetics 51 289-295 Takeshita A,
Imai K and Hanazawa S (1999) CpG motifs in Porphyromonas gingivalis DNA
stimulate interleukin-6 expression in human gingival fibroblasts. Infection
and Immunity 67 4340-4345 Takeshita F
and Klinman DM (2000) CpG ODN-mediated regulation of IL-12 p40 transcription.
European Journal of Immunology 30 1967-1976 Takeshita F, Ishii KJ, Kobiyama K, Kojima Y, Coban C, Sasaki S, Ishii N, Klinman DM, Okuda K, Akira S and Suzuki K (2005) TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF. European Journal of Immunology 35 2477-2485 Takeshita F, Ishii KJ, Ueda A, Ishigatsubo Y and Klinman DM
(2000) Positive and negative regulatory elements contribute to CpG
oligonucleotide-mediated regulation of human IL-6 gene expression. European
Journal of Immunology 30 108-116 Takeshita F, Suzuki K, Sasaki S, Ishii N, Klinman DM, Ishii KJ (2004) Transcriptional regulation of the human TLR9 gene. Journal of Immunology 173 2552-2261 Takeshita H,
Yoshizaki T, Miller WE, Sato H, Furukawa M, Pagano JS and Raab-Traub N (1999)
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent
membrane protein 1 C-terminal activation regions 1 and 2. Journal of Virology
73 5548-5555 Takeshita K,
Suzuki Y, Nishio K, Aoki T, Takeuchi O, Toda K, Sato N, Naoki K, Kudo H and
Yamaguchi K (1999) Hyperoxia and hypercapnic acidosis differentially alter
nuclear factor-kappa B activation in human pulmonary artery endothelial
cells. Advances in Experimental Medicine and Biology 471 265-270 Taketa T, Sakai A, Tanaka S, Nakai K, Menuki K, Yamane H, Tanaka K and Nakamura T (2008) Selective cyclooxygenase-2 inhibitor prevents reduction of trabecular bone mass in collagen-induced arthritic mice in association with suppression of RANKL/OPG ratio and IL-6 mRNA expression in synovial tissues but not in bone marrow cells. Journal of Bone and Mineral Metabolism 26 143-151 Takeuchi D, Yoshidome H, Kato A, Ito H, Kimura F, Shimizu H, Ohtsuka M, Morita
Y and Miyazaki M (2004) Interleukin 18 causes hepatic ischemia/reperfusion
injury by suppressing anti-inflammatory cytokine expression in mice.
Hepatology 39 699-710 Takeuchi K, Itoh H, Yonemitsu Y, Matsumoto T, Kume M, Komori K and Maehara Y (2007) In vivo reduction of the nuclear factor-kB activity using synthetic cis-element decoy oligonucleotides suppresses intimal hyperplasia in the injured carotid arteries in rabbits. Surgery Today 37 575-583 Takeuchi M
and Baichwal VR (1995) Tumor necrosis factor-alpha induction of MAdCAM-1 gene
is mediated by NF-kB proteins. Proceedings of the National Academy of
Sciences USA 92 3561-3565 Takeuchi M,
Rothe M and Goeddel DV (1996) Anatomy of TRAF2: distinct domains for Nuclear
Factor-kB activation and association with tumor necrosis factor signaling
proteins. Journal of Biological Chemistry 271 19935-19942 Takeuchi
O and Akira S (2001) Toll-like receptors; their physiological role and signal
transduction system. International Immunopharmacology 1 625-635 Takeuchi O, Hemmi H and Akira S (2004) Interferon response induced by Toll-like receptor signaling. Journal of Endotoxin Research 10 252-256 Takeuchi O,
Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K and Akira S (1999)
Differential roles of TLR2 and TLR4 in recognition of gram-negative and
gram-positive bacterial cell wall components. Immunity 11 443-451 Takeuchi O,
Kawai T, Sanjo H, Copeland NG, Gilbert DJ, Jenkins NA, Takeda K and Akira S
(1999) TLR6: A novel member of an expanding toll-like receptor family. Gene
231 59-65 Takeuchi T, Kobayashi T, Tamaura S and Yokosawa H (2006) Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation. FEBS Letters 580 4521-4526 Takeuchi T, Miura S, Wang L, Uehara K, Mizumori M,
Kishikawa H, Hokari R, Higuchi H, Adachi M, Nakamizo H and Ishii H (2002)
Nuclear factor-kB and TNF-alpha mediate gastric ulceration induced by phorbol
myristate acetate. Dig Dis Sci 47 2070-2078 Takeuchi Y and
Fukunaga K (2003) Differential regulation of NF-kB, SRE and CRE by dopamine D1
and D2 receptors in transfected NG108-15 cells. Journal of Neurochemistry 85
729-739 Takeyama K,Mitsuzawa H, Nishitani C, Shimizu T, Sano H, Kunishima Y, Takahashi S, Hotta H, Matsukawa M, Shibata KI, Tsukamoto T and Kuroki Y (2006) 6-Fluoro-8-methoxy-quinolone, gatifloxacin, down-regulates IL-8 production in prostate cell line PC-3. Antimicrobial Agents and Chemotherapy in press Takeyama K,
Mitsuzawa H, Shimizu T, Konishi M, Nishitani C, Sano H, Kunishima Y, Matsukawa
M, Takahashi S, Shibata KI, Tsukamoto T and Kuroki Y (2005) Prostate cell
lines secrete IL-8 in response to mycoplasma hominis through Toll-like
receptor 2-mediated mechanism. Prostate 66 386-391 Takezako N, Hayakawa M, Hayakawa H, Aoki S, Tanagisawa K, Endo H and Tominaga SI (2006) ST2 suppresses IL-6 production via the inhibition of IkB degradation induced by the LPS signal in THP-1 cells. Biochemical and Biophysical Research Communications 341 425-432 Takigawa N, Vaziri SA, Grabowski DR, Chikamori K, Rhbicki LR, Bukowski RM, Ganapathi MK, Ganapthi R and Mekhail T (2006) Proteasome inhibition with bortezomib enhances activity of topoisomerase I-targeting drugs by NF-kB-independent mechanisms. Anticancer Research 26 1869-1876 Takizawa BT, Uchio EM, Cohen JJ, Wheeler MA and Weiss Rm (2007) Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kB signaling in urothelial cancer cells. Cancer Investigations 25 678-684 Takizawa H,
Ohtoshi T, Kawasaki S, Kohyama T, Desaki M, Kasama T, Kobayashi K, Nakahara
K, Yamamoto K, Matsushima K and Kudoh S (1999) Diesel exhaust particles
induce NF-kB activation in human bronchial epithelial cells in vitro:
importance in cytokine transcription. Journal of Immunology 162 4705-4711 Takizawa K,
Kamijo R, Ito D, Hatori M, Sumitani K and Nagumo M (1999) Synergistic
induction of ICAM-1 expression by cisplatin and 5-fluorouracil in a cancer
cell line via a NF-kB independent pathway. British Journal of Cancer 80
954-963 Talreja J, Kabir MH, B Filla M, Stechschulte DJ and Dileepan KN (2004)
Histamine induces Toll-like receptor 2 and 4 expression in endothelial cells
and enhances sensitivity to Gram-positive and Gram-negative bacterial cell
wall components. Immunology 113 224-233 Tam
WF, Lee
LH, Davis L and Sen R (2000) Cytoplasmic sequestration of Rel proteins by
IkBa requires CRM1-dependent nuclear export. Molecular and Cellular Biology
20 2269-2284 Tam
WF, Wang W and Sen R (2001) Cell-specific association and shuttling of IkBa provides a mechanism for nuclear NF-kB in B lymphocytes.
Molecular and Cellular Biology 21 4837-4846 Tamada K, Shimozaki K, Chapoval AI, Zhai Y, Su J, Chen SF,
Hsieh SL, Nagata S, Ni J and Chen L (2000) LIGHT, a TNF-like molecule,
costimulates T cell proliferation and is required for dendritic cell-mediated
allogeneic T cell response. Journal of Immunology 164 4105-4110 Tamada S, Asai T, Kuwabara N, Iwai T, Uchida J, Teramoto K, Kaneda N, Yukimura T, Nakatani T and Miura K (2006) Molecular mechanisms and therapeutic strategies of chronic renal injury: the role of nuclear factor kB activation in the development of renal fibrosis. Journal of Pharmacological Sciences 100 17-21 Tamada S,
Nakatani T, Asai T, Tashiro K, Komiya T, Sumi T, Okamura M, Kim S, Iwao H,
Kishimoto T, Yamanaka S and Miura K (2003) Inhibition of nuclear factor-kB
activation by pyrrolidine dithiocarbamate prevents chronic FK506 nephropathy.
Kidney International 63 306-314 Tamai R, Asai Y, Hashimoto M, Fukase K, Kusumoto S, Ishida H, Kiso M and Ogawa
T (2003) Cell activation by monosaccharide lipid A analogues utilizing
Toll-like receptor 4. Immunology 110 66-72 Tamanini A, Nicolis E, Bonizzato A, Bezzerri V, Melotti P, Assael BM and Cabrini G (2006) Interaction of Adenovirus type 5 fiber with the Coxsackie adenovirus receptor activates inflammatory response in human respiratory cells. Journal of Virology 80 11241-11254 Tamanini A, Rolfini R, Nicolis E, Melotti P and Cabrini G (2003) MAP kinases and NF-kB collaborate to induce ICAM-1 gene expression in the early phase of adenovirus infection. Virology 307 228-242 Tamaoki J, Kadota J and Takizawa H (2004) Clinical implications of the immunomodulatory effects of macrolides. American Journal of Medicine 117 5S-11S Tamarkin FJ, Kang WS, Cohen JJ, Wheeler MA and Weiss RM (2006) A role for Akt in the rapid regulation of inflammatory and apoptotic pathways in mouse bladder. Naunyn Schmiedeberg's Archives of Pharmacology 373 349-359 Tamatani T, Azuma M, Ashida Y, Motegi K, Takashima R, Harada K,
Kawaguchi S
and Sato M (2004) Enhanced radiosensitization and chemosensitization in
NF-kB-suppressed human oral cancer cells via the inhibition of
gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8. International
Journal of Cancer 108 912-921 Tammali R, Ramana KV, Singhal SS, Awasthi S and Srivastava SK (2006) Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin e2 production in human colon cancer cells. Cancer Research 66 9705-9713
Tamaru M and
Narumi S (1999) E-selectin gene expression is induced synergistically with
the coexistence of activated classic protein kinase C and signals elicited by
interleukin-1beta but not tumor necrosis factor-alpha. Journal of Biological
Chemistry 274 3753-3763 Tamatani M,
Che YH, Matsuzaki H, Ogawa S, Okado H, Miyake S-i, Mizuno T and Tohyama M
(1999) Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkB
activation in primary hippocampal neurons. Journal of Biological Chemistry
274 8531-8538 Tamatani
T, Azuma M, Aota K, Yamashita T, Bando T and Sato M (2001) Enhanced IkB
kinase activity is responsible for the augmented activity of NF-kB in human
head and neck carcinoma cells. Cancer Letters 171 165-172 Tammali R, Ramana KV and Srivastava SK (2007) Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Letters in press
Tamura K, Noyama T, Ishizawa YH, Takamatsu N, Shiba T and Ito M (2003) Xenopus death receptor-M1 and-M2, new members of the tumor necrosis factor receptor superfamily, trigger apoptotic signaling by differential mechanisms. Journal of Biological Chemistry 279 7629-7635
Tamura M, Sebastian S, Yang S, Gurates B, Ferrer K, Sasano H, Okamura K and Bulun SE (2002) Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells: A paracrine effect mediated by prostaglandin E2 and nuclear factor-kB. Journal of Biological Chemistry 277 26208-26216
Tamura M, Sebastian
S, Yang S, Gurates B, Fang Z and Bulun SE (2002) Interleukin-1beta elevates
cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA
stability in human endometrial stromal cells: an effect mediated by
extracellularly regulated kinases 1 and 2. Journal of Clinical Endocrinology
and Metabolism 87
3263-3273
Tan C, Li Y, Tan X, Pan H and Huang W (2006) Inhibitiono f the ubiquitin-proteasome system: a new avenue for atherosclerosis. Clincal Chemistry and Laboratory Medicine 44 1218-1225
Tan C, Mui A and Dedhar S
(2002) Integrin-linked
kinase regulates inducible nitric oxide synthase and cyclooxygenase-2
expression in an NF-kB-dependent manner. Journal of Biological Chemistry 277
3109-3116
Tan JE-L, Wong S-C, Gan SK-E, Xu S
and Lam K-P (2001) The adaptor protein BLNK is required for B cell antigen
receptor-induced activation of nuclear factor-kB and cell cycle entry and
survival of B lymphocytes. Journal of Biological Chemistry 276 20055-20063
Tan JX, Huang YG, Huang DN and Huang XL (2004) Effect of adenosine on activity
of transcription factor NF-kB and cytokines in myocardial tissue of
experimental rats with pneumonia [Article in Chinese]. Zhonghua Er Ke Za Zhi
42 433-436 Tan KS, Nackley AG, Satterfield K, Maixner W, Diatchenko L and Flood PM (2006) beta(2) adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kB-independent mechanisms. Cellular Signaling 19 251-260 Tan PH, Sagoo P, Chan C,
Yates JB, Campbell J, Beutelspacher SC, Foxwell BM, Lombardi G and George AJ
(2005) Inhibition of NF-kB and oxidative pathways in human dendritic cells by
antioxidative vitamins generates regulatory T cells. Journal
of Immunology 174 7633-7644 Tan SD, de Vries TJ, Kuijpers-Jagtman AM, Semeins CM, Everts V adn Klein-Nulend J (2007) Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption. Bone in press Tan T-H,
Huang GP, Sica A, Ghosh P, Young HA, Longo DL and Rice NR (1992) kB site-dependent activation of the interleukin-2 receptor a-chain gene promoter
by human c-Rel. Molecular and Cellular Biology 12 4067-4075 Tan X, Sun X,
Gonzalez-Crussi FX, Gonzalez-Crussi F and Hsueh W (1994) PAF and TNF increase
the precursor of NF-kB p50 mRNA in mouse intestine: quantitative analysis by
PCR. Biochimica et Biophysica Acta 1215 157-162 Tan X, Weng T, Zhang J, Wang J, Li W, Wan H, Lan Y, Cheng X, Hou N, Liu H, Ding J, Lin F, Yang R, Gao X, Chen D and Yang X (2007) Smad4 is required for maintaining normal murine postnatal bone homeostasis. Journal of Cell Science in press
Tan Y, Lu ZP, Ou SN and Zhang X (2005) Experimental study on effect of
baoganning on activity of nuclear transcription factor-kB in hepatic stellate
cells [Article in Chinese]. Zhongguo
Zhong Xi Yi Jie He Za Zhi 25 804-807 Tan ZH, Yu LH, Wei HL and Liu GT (2007) The protective action of scutellarin against immunological liver injury induced by concanavalin A and its effect on pro-inflammatory cytokines in mice. Journal of Pharmacy and Pharmacology 59 115-121 Tanabe SI, Bodet C and Grenier D (2008) Treponema denticola lipooligosaccharide activates gingival fibroblasts and upregulates inflammatory mediator production. Journal of Cell Physiology in press Tanabe T, Ishige I, Suzuki Y, Aita Y, Furukawa A, Ishige Y, Uchida K, Suzuki T, Takemura T, Ikushima S, Oritsu M, Yokoyama T, Fujimoto Y, Fukase K, Inohara N, Nunez G and Eishi Y (2006) Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes. Biochimica et Biophysica Acta 1762 794-801
Tanabe T and Tohnai N (2002) Cyclooxygenase isozymes
and their gene structures and expression. Prostaglandins and Other Lipid Mediators
68-69 95-114 Tanaka A, Muto S, Konno M, Itai A and Matusda H (2006) A new IkB kinase b inhibitor prevents human breast cancer progression through negative regulation of cell cycle transition. Cancer Research 66 419-426 Tanaka F, Kawakami A, Tamai M, Nakamura H, Iwanaga N, Izumi Y, Arima K, Aratake K, Huang M, Kamachi M, Ida H, Origuchi T and Eguchi K (2005) IFN-gamma/JAK/STAT pathway-induced inhibition of DR4 and DR5 expression on endothelial cells is cancelled by cycloheximide-sensitive mechanism: Novel finding of cycloheximide-regulating death receptor expression. International Journal of Molecular Medicine 15 833-839 Tanaka H, Fujita N and Tsuruo T (2005) PDK1-mediated IKKb phosphorylation activates NF-kB signaling. Journal of Biological Chemistry 280 40965-40973 Tanaka H, Matsuki H, Furukawa S, Sagisaka A, Kotani E, Mori H and Yamakawa M (2007) Identification and functional analysis of Relish homologs in the silkworm, Bombyx mori. Biochimica et Biophysica Acta in press
Tanaka H, Matsumura I, Ezoe S,
Satoh Y, Sakamaki T, Albanese C, Machii T, Pestell RG and Kanakura Y
(2002) E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kB
activity that facilitates MnSOD-mediated ROS elimination. Molecular Cell 9
1017-1029 Tanaka H,Uchida Y, Kaibori M, Hijakawa T, Ishizaki M, Yamada M, Matsui K, Ozaki T, Tokuhara K, Kamiyama Y, Nishizawa M, Ito S and Okumura T (2007) Na(+)/H(+) exchanger inhibitor, FR183998, has protective effect in lethal acute liver failure and prevents iNOS induction in rats. Journal of Hepatology in press Tanaka H, Yoshida K, Okamura H, Morimoto H, Nagata T and Heneji T (2007) Calyculin A induces apoptosis and stimulates phosphorylation of p65NF-kB in human osteoblastic osteosarcoma MG63 cells. International Journal of Oncology 31 389-396 Tanaka K, Hasegawa J, Asamitsu K and Okamoto T (2005) Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor kB inhibitor parthenolide. Journal of Pharmacology and Experimental Therapeutics 31 624-630 Tanaka K, Hasegawa J, Asamitsu K and Okamoto T (2007) Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kB. European Journal of Pharmacology 565 212-219 Tanaka K, Kyosawa N, Honda K, Sharyo S, Ito K, Teranishi M and Manabe S (2007) Resistance to the skeletal muscle injury expressed by repeated treatment with compound A that has HMG-CoA reductase inhibitory activity. Journal of Toxicological Sciences 32 9-18 Tanaka K, Kobayashi N, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Narushima M, Miki A, Okitsu T, Noguchi H and Tanaka N (2006) Prolonged survival of mice with acute liver failure with transplantation of monkey hepatocytes cultured with an antiapoptotic pentapeptide v5. Transplantation 81 427-437 Tanaka M, Fuentes ME, Yamaguchi K, Duinin MH, Dalrymple SA, Hardy KL and Goeddel DV (1999) Embryonic lethality, liver degeneration and impaired NF-kB activation in IKK-b-deficient mice. Immunity 10 421-429 Tanaka S (2005) Intracellular signal transduction pathways: good therapeutic targets for joint destruction in rheumatoid arthritis. Modern Rheumatology 15 19-27 Tanaka S (2007) RANKL as a target molecule for treatment of joint destruction [Article in Japanese]. Clinical Calcium 17 586-592 Tanaka S, Takehashi M, Matoh
N, Iida S, Suzuki T, Futaki S, Hamada H, Masliah E, Sugiura Y and Ueda K
(2002) Generation of reactive oxygen species and activation of NF-kB by non-Abeta
component of Alzheimer's disease amyloid. Journal of Neurochemistry 82 305-315 Tanaka T, Legat A, Adam E, Steuve J, Gatot JS, Vandenbranden M, Ulianov L, Lonez C, Ruysschaert J, Muraille E, Tuynder M, Goldman M and Jacquet A (2008) DiC14-amidine cationic liposomes stimulate myeloid dendritic cells through Toll-like receptor 4. European Journal of Immunology in press Tanaka T, Oh-Hashi K, Shitara H, Hirata Y and Kuchi K (2007) NF-kB independent signaling pathway is responsible for LPS-induced GDNF gene expression in primary rat glial cultures. Neuroscience Letters in press Tanaka Y (2008) Immunosuppressive effects of glucocoriticoid [Article in Japanese]. Nippon Rinsho 66 83-88
Tanaka Y, Kobayashi H, Suzuki M, Kanayama N and Terao T (2004) Transforming
growth factor-beta 1-dependent urokinase up-regulation and promotion of
invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer
cells. Journal of Biological Chemistry 51 83-90 Tando Y, Algul
H, Schneider G, Weber CK, Weidenbach H, Adler G and Schmid RM (2002) Induction
of IkB-Kinase by cholecystokinin is mediated by trypsinogen activation in rat
pancreatic lobules. Digestion 66 237-245 Tang CH, Chuang JY, Fong YC, Maa MC, Way TD and Hung CH (2008) Bone-derived SDF-1 stimulates IL-6 Release via CXCR4, ERK and NF-kB pathways and promoting osteoclastogenesis in human oral cancer cells. Carcinogenesis in press Taniguchi M, Takeuchi T, Nakatsuka R, Watanabe T and Sato K (2004) Molecular
process in acute liver injury and regeneration induced by carbon
tetrachloride. Life Sci 751539-1549 Tang CH, Chuang JY, Fong YC, Maa MC, Way TD and Hung CH (2008) Bone-dervied SDF-1 stimulates IL-6 release via CSCR4, ERK and NF-kB pathways and promoting osteoclastogenesis in human oral cancer cells. Carcinogenesis in press Tang CH, Huang TH, Chang CS, Fu WM and Yang RS (2008) Water solution of onion crude powder inhibits RANKL-induced osteoclastogenesis through ERK, p38 and NF-kB pathways. Osteoporos International in press Tang CH, Lu DY, Yang RS, Tsai HY, Kao MC, Fu WM and Chen YF (2007) Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor Substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kB, and p300 pathway in microglia. Journal of Immunology 179 1292-< |