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References Relevant publications listed by the last name of
the first author. Saadane A, Masters S, Didonato J, Li J and Berger M (2007) Parthenolide inhibits I{kappa} B Kinase, NF-kB activation and inflammatory response in CF cells and mice. American Journal of Respiratory Cell and Molecular Biology 36 728-736 Saadane A, Soltys J and Berger M (2005) Role of IL-10 deficiency in excessive nuclear factor-kB activation and lung inflammation in cystic fibrosis transmembrane conductance regulator knockout mice. Journal of Allergy and Clinical Immunology 115 405-411
Saadane
A, Soltys J and Berger M (2006) Acute Pseudomonas challenge in cystic fibrosis
mice causes prolonged nuclear factor-kB activation, cytokine secretion, and
persistent lung inflammation.
Saas J, Haag J, Rueger D, Chubinskaya S, Sohler F, Zimmer R, Bartnik E and Aigner T (2006) IL-1beta, but not BMP-7 leads to a dramatic change in the gene expression pattern of human adult articular chondrocytes - portraying the gene expression pattern in two donors. Cytokine in press Saatian B, Zhao Y, He D, Georas SN, Watkins T, Spannhake EW and Natarajan V (2005) Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells. Biochemical Journal 393 657-668 Saavedra-Lopes M, Ramalho FS, Ramalho LN, Andrade-Silva A, Martinelli AL, Jordao Jr AA, Castro-E-Silva O, adn Zucoloto S (2008) The protective effect of CAPE on hepatic ischemia/reperfusion injury in rats. Journal of Surgical Research in press Saavalainen K, Tammi MI, Bowen T, Schmitz ML and Carlberg C (2007) Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors RAR and NF-kB. Journal of Biological Chemistry 282 11530-11539
Savedra MT, Patterson AD, West J, Randell SA, Riches DW, Malcolm KC, Cool CD, Nick JA and Dinarello CA (2008) Abrogation of anti-inflammatory transcription factor LKLF in neutrophil dominated airways. American Journal of Respiratory Cell and Molecular Biology in press
Saban
MR, Hellmich HL, Turner M, Nguyen NB, Vadigepalli R, Dyer DW, Hurst RE,
Centola M and Saban R (2006) The inflammatory and normal transcriptome of
mouse bladder detrusor and mucosa.
Saban
MR, Memet S, Jackson DG, Ash J, Roig AA, Israel A and Saban R (2004)
Visualization of lymphatic vessels through NF-kB activity. Blood
104 3228-3330 Saban R, Simpson C, Vadigepalli R, Memet S, Dozmorov I and Saban MR (2007) Bladder inflammatory transcriptome in response to tachykinins: Neurokinin 1 receptor-dependent genes and transcription regulatory elements. BMC Urology in press Sabatini N, Di Pietro R, Rapino M, Sancilio S, Comani S and Cataldi A (2004) PI-3-kinase/NF-kappaB mediated response of Jurkat T leukemic cells to two different chemotherapeutic drugs, etoposide and TRAIL. Journal of Cellular Biochemistry 93 301
Sabatino AD, Morera R, Ciccocioppo R, Cazzola P, Gotti S, Tinozzi FP, Tinozzi S and Corazza GR (2005) Oral butyrate for mildly to moderately active Crohn's disease. Aliment Pharmacol Ther 22 789-794
Sabatucci JP,
Ashwell MA, Trybulski E, O'Donnell MM, Moore WJ, Harnisch DC and Chadwick CC
(2006) Substituted 4-hydroxyphenyl sulfonamides as pathway-selective estrogen
receptor ligands. Bioorganic & Medicinal Chemical Letters 16 854-858 Sabouri Ghannad M and Zamani A (2008 The full length Hepatitis C virus polyprotein and interactions with the interferon-beta signalling pathways in vitro. Iranian Biomedical Journal 12 23-34
Saibil SD, Jones RG, Deenick EK, Liadis N, Elford AR, Vainberg MG, Baerg H, Woodgett JR, Gerondakis S and Ohashi PS (2007) CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. Journal of Immunology 178 2932-2939 Sabolek M, Herborg A, Schwarz J and Storch A (20060 Dexamethasone blocks astroglial differentiation from neural precursor cells. Neuroreport 17 1719-1723
Sabroe I, Prince LR, Jones EC, Horsburgh MJ, Foster SJ, Vogel SN, Dower SK and Whyte MK (20903) Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span. Journal of Immunology 170 5268-5275 Saccani A, Schioppa T, Porta C, Biswas SK, Nebuloni M, Vago L, Bottazzi B, Colombo MP, Mantovani A and Sica A (2006) p50 nuclear factor-kB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Research 66 11432-11440 Saccani S, Marazzi I, Beg AA and Natoli G (2004) Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kB response. Journal of Experimental Medicine 200 107-113
Saccani S,
Pantano S and Natoli G (2001) Two waves of nuclear factor kB recruitment to
target promoters. Journal of Experimental Medicine 193 1351-1359 Saccani S,
Pantano S and Natoli G (2002) p38-Dependent marking of inflammatory genes for
increased NF-kB recruitment. Nature Immunology 3 69-75 Saccani S, Pantano S and Natoli G (2003) Modulation of NF-kB activity by exchange of dimers. Molecular Cell 11 1563-1574 Sachdev S and
Hannink M (1998) Loss of IkBa-mediated control over nuclear import and
DNA-binding enables oncogenic activation of c-Rel. Molecular and Cellular
Biology 18 5445-5456 Sachdev S,
Bagchi S, Zhang DD, Mings AC and Hannink M (2000) Nuclear import of IkBa is
accomplished by a Ran-independent transport pathway. Molecular and Cellular
Biology 20 1571-1582 Sachdev S,
Diehl JA, McKinsey TA, Hans A and Hannink M (1997) A threshold level of the
v-Rel oncoprotein is required for transformation of avian lymphocytes.
Oncogene 14 2585-2594 Sachdev S,
Hoffmann A and Hannink M (1998) Nuclear localization of IkBa is mediated by
the second ankyrin repeat: IkBa ankyrin repeats define a novel class of cis-acting
nuclear import sequences. Molecular and Cellular Biology 18 2524-2534 Sachdev S,
Rottjakob EM, Diehl JA and Hannink M (1995) IkB-a-mediated inhibition of
nuclear transport and DNA-binding by Rel proteins are separable functions:
phosphorylation of C-terminal serine residues of IkB-a is specifically
required for inhibition of DNA-binding. Oncogene 11 811-823 Sachse F, von Eiff C, Becker K, Steinhoff M and Rudack C (2007) Proinflammatory impact of Staphylococcus epidermidis on the nasal epithelium quantified by IL-8 and GRO-alpha responses in primary human nasal epithelial cells. International Archives of Allergy and Immunology 1451 24-32 Sachse F, von Eiff C, Stoll W, Becker K and Rudack C (2006) Induction of CXC chemokines in A549 airway epithelial cells by trypsin and staphylococcal proteases - a possible route for neutrophilic inflammation in chronic rhinosinusitis. Clinical and Experimental Immunology 144 534-542 Sacht G,
Marten A, Diters U, Sussmuth R, Jung G, Wingender E and Muhlradt PF (1998)
Activation of Nuclear Factor-kB in macrophages by mycoplasmal lipopeptides.
European Journal of Immunology 28 4207-4212 Sacks M,
Gordon J, Bylander J, Porter D, Shi XL, Castranova V, Kaczmarczyk W, van Dyke
K and Reasor MJ (1998) Silica-induced pulmonary inflammation in rats:
activation of NF-kB and its suppression by dexamethasone. Biochemical and
Biophysical Research Communications 253 181-184 Sacre SM, Andreakos E, Feldmann M and Foxwell BM (2004) Endotoxin signaling in human macrophages: signaling via an alternate mechanism. Journal of Endotoxin Research 10 445-452 Sacre
SM, Lundberg AM, ANdreakos E, Taylor C, Feldmann M and Foxwell BM (2007)
Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic Acid (LTA)
induced NF-kB activation and cytokine production in primary human cells: TRAM
is an adaptor for LPS and LTA signaling. Sadaie
MR,
Doniger J, Hung CL and Pantazis P (1999) 9-nitrocamptothecin selectively
inhibits human immunodeficiency virus type 1 replication in freshly infected
parental but not 9-nitrocamptothecin-resistant U937 monocytoid cells. AIDS
Research and Human Retroviruses 15 239-245 Sadagopan S, Sharma-Walia N, Veettil MV, Raghu H, Sivakumar R, Bottero V and Chandran B (2007) Kaposi's Sarcoma-Associated herpes virus (KSHV/HHV-8) induces a sustained NF-kB activation during de novo infection of primary human dermal microvascular endothelial Cells that is Essential for viral gene expression. Journal of Virology 81 3949-3968 Sadeghi K, Wessner B, Laggner U, Ploder M, Tamandl D, Friedl J, Zugel U, Steinmeyer A, Pollak A, Roth E, Boltz-Nitulescu G and Spittler A (2006) Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. European JOurnal of Immunology 36 361-370 Sadeghi MM,
Collinge M, Pardi R and Bender JR (2000) Simvastatin modulates
cytokine-mediated endothelial cell adhesion molecule induction: involvement of
an inhibitory G protein. Journal of Immunology 165 2712-2718 Sadik CD, Hunfeld KP, Bachmann M, Kraiczy P, Eberhardt W, Brade V, Pfeilschifter J and Muhl H (2008) Systematic analysis highlights the key role of TLR2/NF-kappaB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. INternational Journal of Biochemistry and Cell Biology in press Sadikot RT, Christman JW and Blackwell TS (2004) Molecular targets for modulating lung inflammation and injury. Current Drug Targets 5 581-588 Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW and Blackwell TS (2003) Selective IkB kinase expression in airway epithelium generates neutrophilic lung inflammation. Journal of Immunology 170 1091-1098 Sadikot RT, Wudel LJ, Jansen DE, Debelak JP, Yull FE, Christman JW, Blackwell TS and Chapman WC (2002) Hepatic cryoablation-induced multisystem injury. Bioluminescent detection of NF-kappaB activation in a transgenic mouse model. Journal of Gastrointesttinal Surgery 6 264-270 Sadikot RT, Zeng H, Joo M, Everhart MB, Sherrill TP, Li B, Cheng DS, Yull FE, Christman JW and Blackwell TS (2006) Targeted immunomodulation of the NF-kB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. Journal of Immunology 176 4923-4930 Sadikot RT, Zeng H, Yull FE, Li B, Cheng DS, Kernodle DS, Jansen ED, Contag CH, Segal BH, Holland SM, Blackwell TS and Christman JW (2004) p47(phox) deficiency impairs NF-kB activation and host defense in Pseudomonas pneumonia. Journal of Immunology 172 1801-1808 Sadler TM, Achilleos M, Ragunathan S, Pitkin A, LaRocque J, Morin J, Annable R, Greenberger LM, Frost P and Zhang Y (2004) Development and comparison of two nonradioactive kinase assays for IkB kinase. Analytical Biochemistry 326 106-113 Sae-Ung N, Matsushima T, Choi I, Abe Y, Winichagoon P, Fucharoen S, Nawata H and Muta K (2005) Role of NF-kB in regulation of apoptosis of erythroid progenitor cells. European Journal of Haematology 74 315-323 Saeed RW, Peng T and Metz CN (2003) Ascorbic acid blocks the growth inhibitory effect of tumor necrosis factor-alpha on endothelial cells. Experimental Biology and Medicine 228 855-865 Saeed RW, Varma S, Peng T, Tracey KJ, Sherry B and Metz CN (2004) Ethanol blocks leukocyte recruitment and endothelial cell activation in vivo and in vitro. Journal of Immunology 173 6376-6383 Saeed RW, Varma S, Peng-Nemeroff T, Sherry B, Balakhaneh D, Huston J, Tracey KJ, Al-Abed Y and Metz CN (2005) Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. Journal of Experimental Medicine 201 1113-1123 Saegusa M, Hashimura m, Kuwata T, Hamano M and Okayasu I (2007) Crosstalk between NF-kappaB/p65 and beta-catenin/TCF4/p300 signalling pathways through alterations in GSK-3b expression during trans-differentiation of endometrial carcinoma cells. Journal of Pathology in press Saeij JP, Verburg-van Kemenade LB, van Muiswinkel WB and Wiegertjes GF (2003) Daily handling stress reduces resistance of carp to Trypanoplasma borreli: in vitro modulatory effects of cortisol on leukocyte function and apoptosis. Developmental and Comparative Immunology 27 233-245 Saeij JP, Vries BJ and Wiegertjes GF (2003) The immune response of carp to Trypanoplasma borreli: kinetics of immune gene expression and polyclonal lymphocyte activation. Developmental and Comparative Immunology 27 859-874 Saemann MD, Kelemen P, Bohmig GA, Horl WH and Zlabinger GJ (2004) Hyporesponsiveness in alloreactive T-cells by NF-kB inhibitor-treated dendritic cells: resistance to calcineurin inhibition. American Journal of Transplantation 4 1448-1458 Saemann MD, Weichhart T, Zeyda M, Staffler G, Schunn M, Stuhlmeier KM, Sobanov Y, Stulnig TM, Akira S, Gabain AV, von Ahsen U, Horl WH and Zlabinger GJ (2005) Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4- dependent mechanism. Journal of Clincal Investigation 115 468-475 Safak M,
Gallia GL and Khalili K (1999) A 23-bp sequence element from human neurotropic
JC virus is responsive to NF-kB subunits. Virology 262 178-189 Safieh-Garabedian B, Mouneimne GM, El-Jouni W, Khattar M and Talhouk R (2004) The effect of endotoxin on functional parameters of mammary CID-9 cells. Reproduction 127 397-406 Safina A, Ren MQ, Vandette E and Bakin AV (2007) TAK1 is required for TGF-beta1-mediated regulation of matrix metalloproteinase-9 and metastasis. Oncogene in press Safronova O, Nakahama K, Onodera M, Muneta T and Morita I (2003) Effect of hypoxia on monocyte chemotactic protein-1 (MCP-1) gene expression induced by Interleukin-1beta in human synovial fibroblasts. Inflammation Research 52 480-486 Safronova O, Nakahama K, Onodera M, Muneta T and Morita I (2004) Effect of hypoxia on monocyte chemotactic protein-1 (MCP-1) gene expression induced by Interleukin-1beta in human synovial fibroblasts. Inflammation Research 53 170 Sagaert X, De Wolf-Peeters C, Noels H and Baens M (2007) The pathogenesis of MALT lymphomas: where do we stand. Leukemia in press Sagi SA, Weggen S, Eriksen J, Golde TE and Koo EH (2003) The non-COX targets of NSAIDs, lipoxygenases, PPARs, IKK and NFkB, do not reduce Abeta 42 production. Journal of Biological Chemistry 278 31825-31830 Sagisaka A, Tanaka H, Furukawa S and Yamakawa M (2004) Characterization of a homologue of the Rel/NF-kB transcription factor from a beetle, Allomyrina dichotoma. Biochimica et Biophysica Acta 1678 85-93 Sagoo P, Chan G, Larkin DF and George AJ (2004) Inflammatory cytokines induce apoptosis of corneal endothelium through nitric oxide. Invest Ophthalmol Vis Sci 45 3964-3973 Saha A, Hammond CE, Trojanowska M and Smolka AJ (2008) Helicobacter pylori-induced H,K-ATPase {alpha} subunit gene repression is mediated by NF-kB p50 homodimer promoter binding. American Journal of Physiology: Gastrointestinal Liver Physiology in press Saha RN, Liu S adn Pahan K (2006) Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine. Journal of Neuroimmune Pharmacology 1 212-222 Saha RN, Jana M and Pahan K (2007) MAPK p38 regulates transcriptional activity of NF-kB in primary human astrocytes via acetylation of p65. Journal of Immunology 179 7101-7109 Saha RN and Pahan K (2007) Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: implications for HIV-associated dementia. Free Radic Biology and Medicine 42 1866-1878 Sahali D, Pawlak A, Le Gouvello S, Lang P, Valanciute A, Remy P, Loirat C, Niaudet P, Bensman A and Guellaen G (2001) Transcriptional and post-transcriptional alterations of IkBa in active minimal-change nephrotic syndrome. Journal of the American Society of Nephrology 12 1648-1658 Sahar S, Dwarakanath RS, Reddy MA, Lanting L, Todorov I and Natarajan R (2005) Angiotensin II enhances interleukin-18 mediated inflammatory gene expression in vascular smooth muscle cells -a novel cross-talk in the rathogenesis of atherosclerosis. Circulation Research 96 1064-1071 Sahni A, Guo M, Sahni SK and Francis CW (2004) Interleukin-1{beta} but not IL-1{alpha} binds to fibrinogen and fibrin and has enhanced activity in the bound form. Blood 10 4 409-414 Sahni SK, Rydkina E, Joshi SG, Sporn LA and Silverman DJ (2003) Interactions of Rickettsia rickettsii with endothelial nuclear factor-kB in a "cell-free" system. Annals of the New York Academy of Sciences 990 635-641 Sahni SK,
Turpin LC, Brown TL and Sporn LA (1999) Involvement of protein kinase C in
Rickettsia rickettsii-induced transcriptional activation of the host
endothelial cell. Infection and Immunity 67 6418-6423 Sahnoun Z,
Jamoussi K and Zeghal KM (1998) Free radicals and antioxidants: physiology,
human pathology and therapeutic aspects. Therapie 53 315-339 Saibil SD, Jones RG, Deenick EK, Liadis N, Elford AR, Vainberg MG, Baerg H, Woodgett JR, Gerondakis S and Ohashi PS (2007) CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. Journal of Immunology 178 2932-2939 Said FA,
Werts C, Elalamy I, Couetil JP, Jacquemin C and Hatmi M (2002) TNF-alpha,
inefficient by itself, potentiates IL-1beta-induced PGHS-2 expression in human
pulmonary microvascular endothelial cells: requirement of NF-kB and p38 MAPK
pathways. British Journal of Pharmacology 136 1005-1014 Saijo K,
Mecklenbrauker I, Santana A, Leitger M, Schmedt C and Tarakhovsky A (2002)
Protein kinase C beta controls nuclear factor kB activation in B cells through
selective regulation of the IkB kinase alpha. Journal of Experimental Medicine
195 1647-1652 Saijo K, Mecklenbrauker I, Schmedt C and Tarakhovsky A (2003) B cell immunity regulated by the protein kinase C family. Annals of the New York Academy of Sciences 987 125-134 Saijo K, Schmedt C, Su IH, Karasuyama H, Lowell CA, Reth M, Adachi T, Patke A, Santana A and Tarakhovsky A (2003) Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nature Immunology 4 274-279 Saika S, Ikeda K, Yamanaka O, Miyamoto T, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Nakajima Y, Kao WW, Flanders KC and Roberts AB (2005) Expression of smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali. American Journal of Patholog 166 1405-1418 Saika S, Miyamoto T, Yamanaka O, Kato T, Ohnishi Y, Flanders KC, Ikeda K, Nakajima Y, Kao WW, Sato M, Muragaki Y and Ooshima A (2005) Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kB, in treatment of corneal alkali burns in mice. American Journal of Pathology 166 1393-1403 Saiko P, Szakmary A, Jaeger W and Szekeres T (2007) Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad? Mutation Research in press Saile B, DiRocco P, Dudas J, El-Armouche H, Sebb H, Eisenbach C, Neubauer K and Ramadori G (2004) IGF-I induces DNA synthesis and apoptosis in rat liver hepatic stellate cells (HSC) but DNA synthesis and proliferation in rat liver myofibroblasts (rMF). Laboratory Investigation 84 1037-1049 Saile B, Eisenbach C, El-Armouche H, Neubauer K and Ramadori G (2003) Antiapoptotic effect of interferon-alpha on hepatic stellate cells (HSC): a novel pathway of IFN-alpha signal transduction via Janus kinase 2 (JAK2) and caspase-8. European Journal of Cell Biology 82 31-41 Siasho Y, Hirose H, Horimai C, Miyashita K, Takei I, Umezawa K and Itoh H (2008) Effects of DHMEQ, a novel nuclear factor-kB inhibitor, on beta cell dysfunction in INS-1 cells. Endocrine Journal in press Saito A,
Kamii H, Kato I, Takasawa S, Kondo T, Chan PH, Okamoto H and Yoshimoto T
(2001) Transgenic CuZn-superoxide dismutase inhibits NO synthase induction in
experimental subarachnoid hemorrhage. Stroke
32 1652-1657 Saito F, Yokota H, Sudo Y, Yakabe Y, Takeyama H and Matsunaga T (2006) Application of RNAi inducible TNFRI knockdown cells to the analysis of TNFa-induced cytotoxicity. Toxicology In Vitro in press Saito H and Ishii H (2004) Recent understanding of immunological aspects in alcoholic hepatitis. Hepatology Research 30 193-198 Saito K, Kigawa T, Koshiba S, Sato K, Matsuo Y, Sakamoto A, Takagi T, Shirouzu M, Yabuki T, Nunokawa E, Seki E, Matsuda T, Aoki M, Miyata Y, Hirakawa N, Inoue M, Terada T, Nagase T, Kikuno R, Nakayama M, Ohara O, Tanaka A AND Yokoyama S (2004) The CAP-Gly Domain of CYLD associates with the proline-rich sequence in NEMO/IKKg. Structure (Cambridge) 12 1719-1728 Saito M, Fujisawa A, Nishikomori R, Kambe N, Nakata-Hizume M, Yoshimoto M, Ohmori K, Okafuji I, Yoshioka T, Kusunoki T, Miyachi T, Heike T and Nakahata T (2005) Somatic mosaicism of CIAS1 in a patient with chronic infantile neurologic, cutaneous, articular syndrome. Arthritis and Rheumatism 52 3579-3585 Saito M, Gao J, Basso K, Kitagawa Y, Smith PM, Bhagat G, Pernis A, Pasqualucci L and Dalla-Favera R (2007) A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer Cell 12 280-292 Saito M, Ota Y, Ohashi H, Dei Y, Shimoyama K, Suzuki D, Hayashi H and Ogawa N (2007) CD40-CD40 ligand signal induces the intercellular adhesion molecule-1 expression through nuclear factor-kB p50 in cultured salivary gland epithelial cells from patients with Sjogren's syndrome. Modern Rheumatology 17 45-53 Saito M, Nishikomori R and Kambe N (2007) Familial Mediterranean fever : MEFV gene mutations and treatment. Nihon Rinsho Meneki Gakkai Kaishi 30 78-85 Saito N, Courtois G, Chiba A, Yamamoto N, Nitta T, Hironaka N, Rowe M, Yamamoto N and Yamaoka S (2003) Two C-terminus activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kB through distinct signaling pathways in fibroblast cell lines. Journal of Biological Chemistry 278 6565-46575 Saito S, Matsuura M, Hirai Y (2006) Regulation of lipopolysaccharide-induced interleukin-12 production by activation of repressor element GA-12 through hyperactivation of the ERK pathway. Clin Vaccine Immunology 13 876-883 Saito S,
Matsuura M, Tominaga K, Kirikae T and Nakano M (2000) Important role of
membrane-associated CD14 in the induction of IFN-beta and subsequent nitric
oxide production by murine macrophages in response to bacterial
lipopolysaccharide. European Journal of Biochemistry 267 37-45 Saito T and
Giaid A (1999) Cyclooxygenase-2 and nuclear factor-kB in myocardium of end
stage human heart failure. Congestive Heart Failure 5 222-227 Saito T, Hirai R, Loo YM, Owen D, Johnson CL, Sinha SC, Akira S, Fujita T and Gale Jr M (2006) Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proceedings of the National Academy of Sciences USA in press Saito T, Ji G, Shinzawa H, Okumoto K, Hattori E, Adachi T, Takeda T, Sugahara K, Ito JI, Watanabe H, Saito K, Togashi H, Ishii K, Matsuura T, Inageda K, Muramatsu M and Kawata S (2004) Genetic variations in humans associated with differences in the course of hepatitis C. Biochemical and Biophysical Research Communications 317 335-341 Saitoh H, Masuda T, Zhang XY, Shimura S and Shirato K (2002) Effect of antisense oligonucleotides to nuclear factor-kB on the survival of LPS-induced ARDS in mouse. Experimental Lung Research 28 219-231 Saitoh T, Nakano H, Yamamoto N and Yamaoka S (2002) Lymphotoxin-beta receptor mediates NEMO-independent NF-kB activation. FEBS Letters 532 45-51 Saitoh T, Nakayama M, Nakano H, Yagita H, Yamamoto N and Yamaoka S (2003) TWEAK induces NF-kB2 p100 processing and long-lasting NF-kB activation. Journal of Biological Chemistry 278 36005-36012 Saitoh T, Yamamoto M, Miyagishi M, Taira K, Nakanishi M, Fujita T, Akira S, Yamamoto N and Yamaoka S (2005) A20 is a negative regulator of IFN regulatory factor 3 signaling. Journal of Immunology 174 1507-1512 Saitoh Y, Chun-Ping C, Noma K, Ueno H, Mizuta M and Nakazato M (2007) Pioglitazone attenuates fatty acid-induced oxidative stress and apoptosis in pancreatic beta-cells. Diabetes, Obesitry & Metabolism in press Saitoh Y, Yamamto N, Dewan MZ, Sugimoto H, Martinez BVJ, Iwasaki Y, Matsubara E, Qi X, Saitoh T, Imoto I, Inazawa J, Utsunomiya A, Watanabe T, Masuda T, Yamamto N and Yamaoka S (2008) Overexpressed NF-{kappa}B inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells. Blood in press Saitou Y, Shiraki K, Yamanaka T, Miyashita K, Inoue T, Yamanaka Y, Yamaguchi Y, Enokimura N, Yamamoto N, Itou K, Sugimoto K and Nakano T (2005) Augmentation of tumor necrosis factor family-induced apoptosis by E3330 in human hepatocellular carcinoma cell lines via inhibition of NF kB. World Journal of Gastroenterolology 11 6258-6261
Sajjan U,
Thanassoulis G, Cherapanov V, Lu A, Sjolin C, Steer B, Wu YJ, Rotstein OD,
Kent G, McKerlie C, Forstner J and Downey GP (2001) Enhanced susceptibility to
pulmonary infection with Burkholderia cepacia in Cftr(-/-) mice. Infection and
Immunity 69 5138-5150 Sakaeda Y, Hiroi M, Shimojima T, Iguchi M, Kanegae H and Ohmori Y (2006) Sulindac, a nonsteroidal anti-inflammatory drug, selectively inhibits interferon-gamma-induced expression of the chemokine CXCL9 gene in mouse macrophages. Biochemical and Biophysical Research Communcations in press Sakaguchi M, Sonegawa H, Murata H, Kitazoe M, Futami JI, Kataoka K, Yamada H and Huh NH (2007) S100A11, a dual mediator for growth regulation of human keratinocytes. Molecular Biology of the Cel in press Sakaguchi M,
Zenzie-Gregory B, Groopman JE, Smale ST and Kim SY (1991) Alternative pathway
for induction of human immunodeficiency virus gene expression: involvement of
the general transcription machinery. Journal of Virology 65 5448-5456 Sakaguchi T,
Nakamura S, Suzuki S, Oda T, Ichiyama A, Baba S and Okamoto T (1999)
Participation of platelet-activating factor in the lipopolysaccharide-induced
liver injury in partially hepatectomized rats. Hepatology 30 959-967 Sakaguchi T,
Sawa Y, Fukushima N, Nishimura M, Ichikawa H, Kaneda Y and Matsuda H (2001) A
novel strategy of decoy transfection against nuclear factor-kB in myocardial
preservation. Ann Thorac Surg 71 624-629; discussion 629-630 Sakai A, Han J, Cato A, Akira S and Li JD (2004) Glucocorticoids synergize with IL-1b to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells. BMC Molecular Biology 5 2 Sakai K,
Kitagawa Y, Li Y, Shirakawa T and Hirose G (2001) Suppression of the
transcriptional activity and DNA binding of nuclear factor-kappa B by a
paraneoplastic cerebellar degeneration-associated antigen. Journal of
Neuroimmunology 119 10-15 Sakai N, Wada T, Furuichi K, Iwata Y, Yoshimoto K, Kitagawa K, Kokubo S, Kobayashi M, Hara A, Yamahana J, Okumura T, Takasawa K, Takeda S, Yoshimura M, Kida H and Yokoyama H (2005) Involvement of extracellular signal-regulated kinase and p38 in human diabetic nephropathy. American Journal of Kidney Disease 45 54-65 Sakai N, Wada T, Furuichi K, Iwata Y, Yoshimoto K, Kitagawa K, Kokubo S, Kobayashi M, Takeda S, Kida H, Kobayashi K, Mukaida N, Matsushima K and Yokoyama H (2002) p38 MAPK phosphorylation and NF-kB activation in human crescentic glomerulonephritis. Nephrology, Dialysis and Transplantation 17 998-1004 Sakaida T, Iwadate Y, Yamaji S, Uehara M, Noda A, Takiguchi M, Yamaura A, Hiwasa T (2003) Acquisition of drug resistance by constitutive suppression of NF-kB in ras-transformed NIH3T3 mouse fibroblasts. International Journal of Oncology 23 1071-1077 Sakamoto A, Yokoyama Y, Umemoto M, Futagami M, Sakamoto T, Bing X and Mizunuma H (2004) Clinical implication of expression of cyclooxygenase-2 and peroxisome proliferator activated-receptor gamma in epithelial ovarian tumours. British Journal of Cancer 91 633-638 Sakamoto N, Mukae H, Fujii T, Ishii H, Yoshioka S, Kakugawa T, Sugiyama K, Mizuta Y, Kadota JI, Nakazato M and Kohno S (2004) Differential effects of alpha- and beta-defensin on cytokine production by cultured human bronchial epithelial cells. American Journal of Physiology: Lung Cell and Molecular Physiology 288 L508-L513 Sakamoto T, Ishibashi T and Maruyma Y (2007) Role of Ca(2)+ influx in tissue factor expression in monocyte adhesion to endothelial cells. Journal of Atherosclerosis and Thrombosis 14 109-115 Sakamoto Y, Harada T, Horie S, Iba Y, Taniguchi F, Yoshida S, Iwabe T and Terakawa N (2003) Tumor necrosis factor-alpha-induced interleukin-8 (IL-8) expression in endometriotic stromal cells, probably through nuclear factor-kB activation: Gonadotropin-Releasing hormone agonist treatment reduced IL-8 expression. Journal of Clinical Endocrinology and Metabolism 88 730-735 Sakao K, Takahashi KA, Mazda O, Arai Y, Tonomura H, Inoue A, Saito M, Fujioka M, Takmiya H, Imainishi J and Kubo T (2008) Enhanced expression of interleukin-6, matrix metalloproteinase-13, and receptor activator of NF-kB ligand in cells derived from osteoarthritic subchondral bone. Journal of Orthpedic Science 13 202-210 Sakata A,
Kuwahara K, Ohmura T, Inui S and Sakaguchi N (1999) Involvement of a rapamycin-sensitive
pathway in CD40-mediated activation of murine B cells in vitro. Immunology Letters
68 301-309 Sakata A, Ochiai T, Shimeno H, Hikishima S, Yokomatsu T, Shibuya S, Toda A, Eyanagi R and Soeda S (2007) Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice. Immunology in press Sakata A, Yasuda K, Ochiai T, Shimeno H, Hikishima S, Yokomatsu T, Shibuya S adn Soeda S (2007) Inhibition of lipopolysaccharide-induced release of interleukin-8 from intestinal epithelial cells by SMA, a novel inhibitor of sphingomyelinase and its therapeutic effect on dextran sulphate sodium-induced colitis in mice. Cellular Immunology in press Sakaue G, Shimaoka M, Fukuoka T, Hiroi T, Inoue T, Hashimoto N, Sakaguchi T, Sawa Y, Morishita R, Kiyono H, Noguchi K and Mashimo T (2001) NF-kB decoy suppresses cytokine expression and thermal hyperalgesia in a rat neuropathic pain model. Neuroreport 12 2079-2084 Saklatvala J
(2002) Glucocorticoids: do
we know how they work? Arthritis Research 4 146-150 Saklatvala J (2007)
Inflammatory signaling in cartilage: MAPK and NF-kB pathways in chondrocytes
and the use of inhibitors for research into pathogenesis and therapy of
osteoarthritis. Sakoda K, Yamamoto M, Negishi Y, Liao JK, Node K and Izumi Y (2006) Simvastatin decreases IL-6 and IL-8 production in epithelial cells. Journal of Dental Research 85 520-523 Sakoda M, Ueno S, Kihara K, Arikawa K, Dogomori H, Nuruki K, Takao S and Aikou T (2004) A potential role of hyperbaric oxygen exposure through intestinal nuclear factor-kB. Critical Care Medicine 32 1722-1729 Sakon S, Xue X, Takekawa M, Sasazuki T, Okazaki T, Kojima Y, Piao JH, Yagita H, Okumura K, Doi T and Nakano H (2003) NF-kB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO Journal 22 3898-3909 Sakuda S,
Tamura S, Yamada A, Miyagawa JI, Yamamoto K, Kiso S, Ito N, Higashiyama S,
Taniguchi N, Kawata S and Matsuzawa Y (2002) NF-kB activation in
non-parenchymal liver cells after partial hepatectomy in rats: possible
involvement in expression of heparin- binding epidermal growth factor-like
growth factor. Journal of Hepatology 36 527-533 Sakurai A,
Hara S, Okano N, Kondo Y, Inoue J and Imura N (1999) Regulatory role of
metallothionein in NF-kB activation. FEBS Letters 455 55-58 Sakurai A, Yuasa K, Shoji Y, Himeno S, Tsujimoto M, Kunimoto M, Imura N and Hara S (2004) Overexpression of thioredoxin reductase 1 regulates NF-kB activation. Journal of Cell Physiology 198 22-30 Sakurai H,
Chiba H, Miyoshi H, Sugita T and Toriumi W (1999) IkB kinases phosphorylate
NF-kB p65 subunit on serine 536 in the transactivation domain. Journal of
Biological Chemistry 274 30353-30356 Sakurai H,
Miyoshi H, Toriumi W and Sugita T (1999) Functional interactions of
transforming growth factor beta-activated kinase 1 with IkB kinases to
stimulate NF-kB activation. Journal of Biological Chemistry 274 10641-10648 Sakurai H,
Nishi A, Sato N, Mizukami J, Miyoshi H and Sugita T (2002) TAK1-TAB1 fusion
protein: a novel constitutively active mitogen-activated protein kinase kinase
kinase that stimulates AP-1 and NF-kB signaling pathways. Biochemical and
Biophysical Research Communications 297 1277 Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, Doi T and Saiki I (2003) TNF-a-induced IKK phosphorylation of NF-kB p65 on serine 536 is mediated through TRAF2, TRAF5 and TAK1 signaling pathway. Journal of Biological Chemistry 278 36916-36923 Sakurai T, Maeda S, Chang L and Karin M (2006) Loss of hepatic NF-kB activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation. Proceedings of the National Academy of Sciences USA in press Sakurai T, Nishioka H, Fuji H, Nakano N, Kuzaki T, Radak Z Izawa T, Haga S and Ohno H (2008) Antioxidative effects of a new lychee fruit-derived polyphenol mixture, oligonol, converted into a low-molecular form in adipocytes. Bioscience, Biotechnology and Biochemistry in press Sakurai T, Terashima S and Miyakoshi J (2007) Enhanced secretion of prostaglandin E(2) from osteoblasts by exposure to a strong static magnetic field. Bioelectromagnetics in press Sala A,
Saitta B, De Luca P, Cervellera MN, Casella I, Lewis RE, Watson R and Peschle
C (1999) B-MYB transactivates its own promoter through SP1-binding sites.
Oncogene 18 1333-1339 Salahuddin SZ,
Markham PD, Lindner SG, Gootenberg J, Popovic M, Hemmi H, Sarin PS and Gallo
RC (1984) Lymphokine production by cultured human T cells transformed by human
T-cell leukemia-lymphoma virus-I. Science 223 703-707 Salaiou C,
Rihn B, Cillard J, Okamoto T and Packer L (1998) Selective inhibition of NF-kB
activation by the flavinoid hepatoprotector silymarin in HepG2. Evidence for
different activating pathways. FEBS Letters 440 8-12 Salama-Cohen P, Arevalo MA, Meier J, Grantyn R and Rodriguez-Tebar A (2005) NGF controls Dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of Notch. Molecular Biology of the Cell 16 339-347 Salanova B, Choi M, Rolle S, Wellner M, Luft FC and Kettritz R (2007) beta 2-integrins and acquired GPIIb/IIIa receptors cooperate in NF-kB activation of human neutrophils. Journal of Biological Chemistry 282 27950-27969 Salanova B, Choi M, Rolle S, Wellner M, Scheidereit C, Luft FC and Kettritz R (2005) The effect of fever-like temperatures on neutrophil signaling. FASEB Journal 19 816-818 Salaun B, Coste I, Rissoan MC, Lebecque SJ and Renno T (2006) TLR3 can directly trigger apoptosis in human cancer cells. Journal of Immunology 176 4894-4901 Salazar R, Brandt R and Krantz S (2001) Binding of Amadori glucose-modified albumin by the monocytic cell line MonoMac 6 activates protein kinase C varepsilon protein tyrosine kinases and the transcription factors AP-1 and NF-kB. Glycoconjate Journal 18 769-777 Salazar-Montes A, Ruiz-Corro L, Lopez-Reyes A, Castrejon-Gomez E and Armendariz-Borunda J (2008) Potent antioxidant role of Pirfenidone in experimental cirrhosis. European Journal of Pharmacology in press Salazar-Montes
A, Ruiz-Corro L, Sandoval-Rodriguez A, Lopez-Reyes A and Armendariz-Borunda J
(2006) Increased
DNA binding activity of NF-kB, STAT-3, SMAD3 and AP-1 in acutely damaged
liver. Saldana M, Bonastre M, Aguilar E and Marin C (2006) Role of nigral NFkB p50 and p65 subunit expression in haloperidol-induced neurotoxicity and stereotyped behavior in rats. European Neuropsychopharmacology 16 491-497 Saldeen J and Welsh N (2004) p38 MAPK inhibits JNK2 and mediates cytokine-activated iNOS induction and apoptosis independently of NF-KB translocation in insulin-producing cells. European Cytokine Network 15 47-52 Saleem M, Afaq F, Adhami VM and Mukhtar H (2004) Lupeol modulates NF-kB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene 23 5203-5214 Salehi E, Vodjgani M, Massoud A, Keyhani A, Rajab A, Shafaghi B, Gheflati Z and Aboufazeli T (2007) Increased expression of TRAIL and its receptors on peripheral T-cells in type 1 diabetic patients. Irnaian Journal of Immunology 4 197-205 Salim AA, Pawlus AD, Chai HB, Farnsworth NR, Douglas Kinghorn A and Carcache-Blanco EJ (2006) Ponapensin, a cyclopenta[bc]benzopyran with potent NF-kB inhibitory activity from Aglaia ponapensis. Bioorganic Medicinal Chemical Letters in press Salinthone S, Singer CA and Gerthoffer WT (2004) Inflammatory gene expression by human colonic smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 287 G627-G637 Saliou C,
Kitazawa M, McLaughlin L, Yang JP, Lodge JK, Tetsuka T, Iwasaki K, Cillard J,
Okamoto T and Packer L (1999) Antioxidants modulate acute solar ultraviolet
radiation-induced NF-kB activation in a human keratinocyte cell line. Free
Radic Biol Med 26 174-183 Saliou C,
Rimbach G, Moini H, McLaughlin L, Hosseini S, Lee J, Watson RR and Packer L
(2001) Solar ultraviolet-induced erythema in human skin and nuclear
factor-kB-dependent gene expression in keratinocytes are modulated by a French
maritime pine bark extract. Free Radic Biol Med 30 154-160. Saliou C,
Valacchi G and Rimbach G (2001) Assessing bioflavonoids as regulators of NF-kB
activity and inflammatory gene expression in mammalian cells. Methods in
Enzymology 335 380-387 Salminen A, Lehtonen M, Suuronen T, Kaarniranta K and Huuskonen J (2008) Terpenoids: natural inhibitors of NF-kB signaling with anti-inflammatory and anticancer potential. Cell and MOlecular Life Sciences in press Salminen, A, Ojala J, Huuskonen J, Kauppinen A, Suuronen T and Kaarniranta K (2008) Interaction of aging-associated signaling cascades: inhibition of NF-kB signaling by longevity factors FoxOs and SIRT1. Cell and Molecular Life Sciences in press Salminen A, Paimela T, Suuronen T and Kaarniranta K (2008) Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90. Immunology Letters 117 9-15 Salminen A, Suuronen T, Huuskonen J and Kaarniranta K (2008) NEMO shuttle: A link between DNA damage and NF-kB activation in progeroid syndromes? Biochemical and Biophysical Research Communications in press Salminen MO,
Johansson B, Sönnerborg A, Ayehunie S, Gotte D, Leinikki P, Burke DS and
McCutchan FE (1996) Full-length sequence of an Ethiopian human
immunodeficiency virus type 1 (HIV-1) isolate of genetic subtype C. AIDS
Research and Human Retroviruses 12 1329-1339 Salmond RJ,
Pitman RS, Jimi E, Soriani M, Hirst TR, Ghosh S, Rincon M and Williams NA
(2002) CD8+ T cell apoptosis induced by Escherichia coli heat-labile
enterotoxin B subunit occurs via a novel pathway involving NF-kB-dependent
caspase activation. European Journal of Immunology 32 1737-1747 Salmond RJ, Williams R, Hirst TR and Williams NA (2004) The B subunit of Escherichia coli heat-labile enterotoxin induces both caspase-dependent and -independent cell death pathways in CD8+ T cells. Infection and Immunity 72 5850-5857 Salonen T, Sareila O, Jalonen Y, Kankaanranta H, Tuominen R and Moilanen E (2006) Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages. British Journal of Pharmacology 147 790-799 Salt BH, Miemela JE, Pandey R, Hanson EP, Deering RP, Quinones R, Jain A, Orange JS and Gelfand EW (2008) IKBKG (nuclear factor-kappaB essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function. Journal of Allergy and Clinical Immunology in press Salter M, Biggadike K, Mathews JL, West MR, Haase MV, Farrow SN, Uings IJ and Gray DW (2007) Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease. American Journal of Physiology: Lung Cellular and Molecular Physiology 293 L660-L667 Saltman LH, Javed A, Ribadeneyra J, Hussain S, Young DW, Osdoby P, Amcheslavsky A, van Wijnen AJ, Stein JL, Stein GS, Lian JB and Bar-Shavit Z (2005) Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1. Journal of Cell Physiology 204 871-880 Salvatore C, Camarda G, Maggi CA, Goso C, Mazini S and Binashi M (2005) NF-kB activation contributes to anthracycline resistance pathway in human ovarian carcinoma cell line A2780. International Journal of Oncology 27 799-806 Sama P, Long TC, Hester S, Tajuba J, Parker J, Chen LC and Veronesi B (2007) The cellular and genomic response of an immortalized microglia cell line (BV2) to concentrated ambeint particulate matter. Inhalation Toxicology 19 1079-1087 Samant RS, Clark DW, Fillmore RA, Cicek M, Metge BJ, Chandramouli KH, Chambers AF, Casey G, Welch DR and Shevde LA (2007) Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kB activation. Molecular Cancer 6 in press Samanta AK, Huang HJ, Bast RC Jr and Liao WS (2004) Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkB. Journal of Biological Chemistry 279 7576-7583 Samanta AK, Lin H, Sun T, Kantarjian H and Arlinghaus RB (2006) Janus kinase 2: a critical target in chronic myelogenous leukemia. Cancer Research 66 6468-6472 Samanta M, Iwakiri D, Kanda T, Imaizumi T and Takada K (2006) EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN. EMBO Journal in press Samanta M, Iwakiri D and Takada K (2008) Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling. Oncogene in press Sambamurti K, Kinsey R, Maloney B, Ge YW and Lahiri DK (2004) Gene structure and organization of the human beta-secretase (BACE) promoter. FASEB Journal 18 1034-1036 Sambucetti
LC, Cherrington JM, Wilinson GWG and Mocarski ES (1989) NF-kB activation of
the cytomegalovirus enhancer is mediated by a viral transactivator and by T
cell stimulation. EMBO Journal 8 4251-4258
Samikkannu T, Thomas JJ, Bhat GJ, Wittman V and Thekkumkara TJ (2006) Acute
effect of high glucose on long-term cell growth: a role for transient glucose
increase in proximal tubule cell injury. Sammons M, Wan SS, Vogel NL, Mientjes EJ, Grosveld G and Ashburner BP (2006) Negative regulation of the RelA/p65 transactivation function by the product of the DEK proto-oncogene. Journal of Biological Chemistry 281 26802-26812 Samapaio EP, Elloumi HZ, Zelazny A, Ding L, Paulson ML, Sher A, Bafica AL, Shea YR and Holland SM (2008) M. abscessus and M. avium trigger Toll like receptor 2 and distinct cytokine response in human cells. American Journal of Respiratory Cell and Molecular Biology in press Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY and Korfhagen TR (2006) Altered postnatal lung development in C3H/HeJ mice. Pediatric Research in press Samperio PM, Barrios JP, Hernandez AV and Martinez EG (2004) Secretion of interleukin-8 by human-derived cell lines infected with Mycobacterium bovis. Mediators Inflamm 13 45-49 Samson JN, van der Marel AP, van Berkel LA, van Helvoort JM, Simons-Oosterhuis Y, Jansen W, Greuter M, Nelissen RL, Meeuwisse CM, Mieuwenhuis EE, Mebius RE and Kraal B (2007) Secretory leukoprotease inhibitor in mucosal lymph node dendritic cells regulates the threshold for mucosal tolerance. Journal of Immunology 179 6588-6595 Samson SI, Memet S, Vosshenrich CA, Colucci F, Richard O, Ndiaye D, Israel A and Di Santo JP (2004) Combined deficiency in IkBa and IkBe reveals a critical window of NF-kB activity in Natural Killer cell differentiation. Blood 103 4573-4580 Samuel CE (2007) Innate immunity minireview series: making biochemical sense of nucleic acid sensors that trigger antiviral innate immunity. Journal of Biological Chemistry 282 15313-15314 Samuel I, Yorek MA, Zaheer A and Fisher RA (2006) Bile-pancreatic juice exclusion promotes Akt/NF-kB activation and chemokine production in ligation-induced acute pancreatitis. Journal of Gastrointestinal Surgery 10 950-959 Samuel I, Zaheer S, Nelson JJ, Yorek MA and Zaheer A (2004) CCK-A receptor induction and P38(MAPK) and NF-kB activation in acute pancreatitis. Pancreatology 4 49-56 Samuel T, Welsh K, Lober T, Togo SH, Zapata JM and Reed JC (2005) Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of TRAF2 and SMAC. Journal of Biological Chemistry in press Samuelsson M, Fisher L and Iverfeldt K (2005) beta-Amyloid and interleukin-1beta induce persistent NF-kB activation in rat primary glial cells. International Journal of Molecular Medicine 16 449-453 Samy TS,
Schwacha MG, Chung CS, Cioffi WG, Bland KI and Chaudry IH (1999) Proteasome
participates in the alteration of signal transduction in T and B lymphocytes
following trauma-hemorrhage. Biochimica et Biophysica Acta 1453 92-104 San
Martin A, Foncea P, Laurindo FR, Ebensperger R, Griendling KK and Leighton F
(2007) Nox1-based NADPH oxidase-derived superoxide is required for VSMC
activation by advanced glycation end-products. San-Antonio B, Iniguez MA and Fresno M (2002) Protein kinase C zeta phosphorylates nuclear factor of activated T cells and regulate its transactivating activity. Journal of Biological Chemistry 277 27073-27080 Sanabani S, Neto WK, Filho DJ, Diaz RS, Munerato P, Janini LM and Sabino EC (2006) Full-length genome analysis of human immunodeficiency virus type 1 subtype C in Brazil. AIDS Research and Human Retroviruses 22 171-176 Sanada S, Hakuno D, Higgins LJ, Schreiter ER, McKenzie AN and Lee RT (2007) IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. Journal of CLinical Investigation 117 1538-1549 Sanagi T, Yabe T and Yamada H (2005) The regulation of pro-inflammatory gene expression induced by pigment epithelium-derived factor in rat cultured microglial cells. Neuroscience Letters 380 105-110 Sanceau J,
Boyd DD, Seiki M and Bauvois B (2002) Interferons inhibit TNF-alpha-mediated
MMP-9 activation via IRF1 binding competition with NF-kB. Journal of
Biological Chemistry 277 35766-35775 Sanceau J,
Kaisho T, Hirano T and Wietzerbin J (1995) Triggering of the human
interleukin-6 gene by interferon-g and tumor necrosis factor-a in monocytic
cells involves cooperation between interferon regulatory factor-1, NF-kB and
Sp1. Journal of Biological Chemistry 270 27920-27931 Sanchez A, Factor VM, Schroeder IS, Nagy P and Thorgeirsson SS (2004) Activation of NF-kappaB and STAT3 in rat oval cells during 2-acetylaminofluorene/partial hepatectomy-induced liver regeneration. Hepatology 39 376-385 Sanchez AC, Davis RL and Syapin PJ (2003) Identification of cis-regulatory regions necessary for robust Nos2 promoter activity in glial cells: indirect role for NF-kB. Journal of Neurochemistry 86 1379-1390 Sanchez AC, Davis RL and Syapin PJ (2007) The Oct DNA motif participates in the alcohol inhibition of the inducible nitric oxide synthase gene promoter in rat C6 glioma cells. Brain Research in press Sanchez AJ, Puerta C, Ballester S, Gonzalez P, Arriaga A and Garcia-Merino A (2005) Rolipram impairs NF-kB activity and MMP-9 expression in experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 168 13-20 Sanchez JF, Sniderhan LF, Williamson AL, Fan S, Chakraborty-Sett S and Maggirwar SB (2003) Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kB signaling. Molecular and Cellular Biology 23 4649-4662 Sanchez Y, Amran D, Fernandez C, de Blas E and Aller P (2008) Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK). International Journal of Cancer in press Sanchez Alcaraz T, Kerkhofs P, Reichert M, Kettmann R and Willems L (2004) Involvement of glutathione as a mechanism of indirect protection against spontaneous ex vivo apoptosis associated with bovine leukemia virus. Journal of Virology 78 6180-6189 Sanchez de
Miguel L, de Frutos T, Gonzalez-Fernandez F, del Pozo V, Lahoz C, Jimenez A,
Rico L, Garcia R, Aceituno E, Millas I, Gomez J, Farre J, Casado S and Lopez-Farre
A (1999) Aspirin inhibits inducible nitric oxide synthase expression and
tumour necrosis factor-alpha release by cultured smooth muscle cells. European
Journal of Clinical Investigation 29 93-99 Sanchez-Beato M, Sanchez E, Garcia JF, Perez-Rosado A, Montoya MC, Fraga M, Jesus Artiga M, Navarrete M, Abraira V, Morente M, Esteller M, Koseki H, Vidal M and Piris MA (2004) Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkB transcription factors. Journal of Pathology 204 528-537 Sanchez-Campos S, Alvarez M, Culebras JM, Gonzalez-Gallego J and Tunon MJ (2004) Pathogenic molecular mechanisms in an animal model of fulminant hepatic failure: Rabbit hemorrhagic viral disease. Journal of Laboratory and Clinical Medicine 144 215-222 Sanchez-Capelo A (2005) Dual role for TGF-beta1 in apoptosis. Cytokine and Growth Factor Reviews 16 15-34 Sanchez-Hidalgo M, Martin AR, Villegas I and Alarcon De La Lastra C (2005) Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces chronic colonic inflammation in rats. Biochemical Pharmacology 69 1733-1744 Sanchez-Hidalgo M, Martin AR, Villegas I and Alarcon De La Lastra C (2007) Rosiglitazone, a PPARgamma ligand, modulates signal transduction pathways during the development of acute TNBS-induced colitis in rats. European Journal of Pharmacology in press Sanchez-Lockhart M, Marin E, Graf B, Abe R, Harada Y, Sedwick CE and Miller J (2004) CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways. Journal of Immunology 173 7120-7124 Sanchez-Lockhart M and mIller J (2006) Engagement of CD28 outside of the immunological synapse results in up-regulation of IL-2 mRNA stability but not IL-2 transcription. Journal of Immunology. 176 4778-4784 Sanchez-Mejorada
G and Rosales C (1998) Fcg receptor-mediated mitogen-activated protein kinase
activation in monocytes is independent of Ras. Journal of Biological Chemistry
273 27610-27619 Sanchez-Sanchez N, Riol-Blanco L, De La Rosa G, Puig-Kroger A, Garcia-Bordas J, Martin D, Longo N, Cuadrado A, Cabanas C, Corbi AL, Sanchez-Mateos P and Rodriguez-Fernandez JL (2004) Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells. Blood 104 619-625 Sanchez-Valdepenas C, Martin AG, Ramakrishnan P, Wallach D and Fresno M (2006) NF-kB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. Journal of Immunology 176 4666-4674 Sanchez-Valdepenas C, Punzon C, San-Antonio B, Martin AG and Fresno M (2006) Differential regulation of p65 and c-Rel NF-kB transactivating activity by Cot, protein kinase C zeta and NIK protein kinases in CD3/CD28 activated T cells. Cell Signaling in press Sancho R, Calzado MA, Di Marzo V, Appendino G and Munoz E (2003) Anandamide inhibits nuclear factor-kB activation through a cannabinoid receptor-independent pathway. Molecular Pharmacology 63 429-438 Sancho R, de la Vega L, Macho A, Appedino G, Di Marzo V and Munoz E (2005) Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. Journal of Immunology 175 3990-3999 Sancho R,
Lucena C, Macho A, Calzado MA, Blanco-Molina M, Minassi A, Appendino G and
Munoz E (2002) Immunosuppressive activity of capsaicinoids: capsiate derived
from sweet peppers inhibits NF-kB activation and is a potent
antiinflammatory compound in vivo. European Journal of Immunology 32 1753-1763 Sancho R, Macho A, De La Vega L, Calzado MA, Fiebich BL, Appendino G and Munoz E (2004) Immunosuppressive activity of endovanilloids: N-arachidonoyl-dopamine inhibits activation of the NF-kB, NFAT, and activator protein 1 signaling pathways. Journal of Immunology 172 2341-2351 Sancho R, Medarde M, Sanchez-Palomino S, Madrigal BM, Alcami J, Munoz E and San Feliciano A (2004) Anti-HIV activity of some synthetic lignanolides and intermediates. Bioorganic & Medicinal Chemistry Letters 14 4483-4486 Sancho-Shimizu V, Zhang SY, Abel L, Tardieu M, Rozenberg F, Jouanguy E and Casanova JL (2007) Genetic susceptibility to herpes simplex virus 1 encephalitis in mice and humans. Current Opinion in Allergy and Clinical Immunology 7 495-505 Sanda T (2007) Transcription factors as therapeutic targets in lymphoid malignancies. International Reviews of Immunology 26 305-332 Sanda T, Asamitsu K, Ogura H, Iida S, Utsunomiya A, Ueda R and Okamoto T (2006) Induction of cell death in adult T-cell leukemia cells by a novel IkB kinase inhibitor. Leukemia in press Sanda T, Iida S, Ogura H, Asamitsu K, Murata T, Bacon KB, Ueda R and Okamoto T (2005) Growth inhibition of multiple myeloma cells by a novel IkB kinase inhibitor. Clinical Cancer Research 11 1974-1982 Sandbo N, Qin Y, Taurin S, Hogarth DK, Kreutz B and Dulin NO (2005) Regulation of SRF-dependent gene expression by proteasome inhibitors. Molecular Pharmacology 67 789-797 Sandborn WJ
and Targan SR (2002) Biologic therapy of inflammatory bowel disease.
Gastroenterology 122 1592-1608 Sandell LJ, Xing X, Franz C, Davies S, Chang LW and Patra D (2008) Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1b. Osteoarthritis and Cartilage in press Sandersen C,
Bureau F, Turlej R, Fievez L, Dogne S, Kirschvink N and Lekeux P (2001) p65
Homodimer activity in distal airway cells determines lung dysfunction in
equine heaves. Vet Immunol Immunopathol 80 315-326 Sanderson LM, de Groot PJ, Hooiveld GJ, Koppen A, Kalkhoven E, Muller M and Kersten S (2008) Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics. PLoS ONE 3 e1681 Sandoval-Chacon
M, Thompson JH, Zhang XJ, Liu X, Mannick EE, Sadowska-Krowicka H, Charbonnet
RM, Clark DA and Miller MJ (1998) Antiinflammatory actions of cat's claw: the
role of NF-kB. Aliment Pharmacol Ther 12 1279-1289 Sandra F,
Matsuki N, Takeuchi H, Ikebe T, Kanematsu T, Ohishi M and Hirata M (2002) TNF
inhibited the apoptosis by activation of Akt serine/threonine kinase in the
human head and neck squamous cell carcinoma. Cell Signaling 14 771-778 Sands BE
(1999) Novel therapies for inflammatory bowel disease. Gastroenterol Clin
North Am 28 323-351 Sands WA, Martin AF, Strong EW and Palmer TM (2004) Specific inhibition of NF-kB-dependent inflammatory responses by cell type-specific mechanisms upon A2A adenosine receptor gene transfer. Molecular Pharmacology 66 1147-1159 Sandulache
VC, Chafin JB, Li-Korotky HS, Otteson TD, Dohar JE and Hebda PA (2007)
Elucidating the role of interleukin 1beta and prostaglandin E2 in upper airway
mucosal wound healing. Sandur SK, Ahn KS, Ichikawa H, Sethi G, Shishodia S, Newman RA and Aggarwal BB (2007) Zyflamend, a polyherbal preparation, inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of NF-kB activation and NF-kB-regulated gene products. Nutrition and Cancer 57 78-87 Sandur SK, Ichikawa H, Pandey MK, Kunnumakkara AB, Sung B, Sethi G and Aggarwal BB (2007) Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane). Free Radical Biology and Medicine 43 568-580 Sandur SK, Ichikawa H, Sethi G, Ahn KS and Aggarwal BB (2006) Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kB activation and NF-kB-regulated gene products through modulation of p65 and IkBa kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agent. Journal of Biological Chemistry 281 17023-17033 Sandur SK, Pandey MK, Sung B, Ahn KS, Murakami A, Sethi G, Limtrakul P, Badmaev V and Aggarwal BB (2007) Curcumin, demethoxycurcumin, bisdemothoxycurcumin, tetrahydrocurcumin, and turmerones differentially regulate anti-inflammatory and antiproliferative responses through a ROS-independent mechanism. Carcinogenesis in press Sang H,
Wallis GL, Stewart CA and Kotake Y (1999) Expression of cytokines and
activation of transcription factors in lipopolysaccharide-administered rats
and their inhibition by phenyl N-tert-butylnitrone (PBN). Archives of Biochemistry
and Biophysics
363 341-348 Sang N, Zhang J and Chen C (2007) COX-2 oxidative metabolite of endocannabinoid 2-AG enhances excitatory glutamatergic synaptic transmission and induces neurotoxicity. Journal of Neurochemistry in press Sang Choe E, Warrier B, Soo Chun J, Cheol Park J and Lee CH (2004) EDTA-induced activation of Ca-regulated proteins in the vaginal mucosa. Journal of Biomedical Materials Reseearch 68A 159-167 Sangai T, Fujimoto H, Miyamoto S, Maeda H, Nakamura M, Ishi G, Nagai K, Nagashima T, Miyazaki M aand Ochiai A (2008) Roles of osteoclasts and bone-derived IGFs in the survival and growth of human breast cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice. Clincal and Experimental Metastasis in press Sangrador-Vegas A, Smith TJ and Cairns MT (2004) Cloning and characterization of a homologue of the alpha inhibitor of NF-kB in Rainbow trout (Oncorhynchus mykiss). Veterinary Immunology and Immunopathology 103 1-7 Sanguino E, Roglans N, Alegret M, Sanchez RM, Vazquez-Carrera M and Laguna JC (2004) Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs. Biochemical Pharmacology 68 1411-1421 Sangwan V, Paliouras GN, Cheng A, Duge N, Tremblay ML and Park M (2005) Protein tyrosine phosphatase 1B deficiency protects against fas-induced hepatic failure. Journal of Biological Chemistry in press Sanjabi S, Hoffmann A, Liou HC, Baltimore D, Smale ST (2000) Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages. Proceedings of the National Academy of Sciences USA 97 12705-12710 Sanjabi S, Williams KJ, Saccani S, Zhou L, Hoffmann A, Ghosh G, Gerondakis S, Natoli G and Smale ST (2005) A c-Rel subdomain reponsible for enhanced DNA-binding affinity and selective gene activation. Genes & Development 19 2138-2151 Sanjo H, Takeda K, Tsujimura T, Ninomiya-Tsuji J, Matsumoto K and Akira S (2003) TAB2 Is Essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling. Molecular and Cellular Biology 23 1231-1238 Sankar S, Chan H, Romanow WJ, Li J and Bates RJ (2005) IKK-i signals through IRF3 and NFkB to mediate the production of inflammatory cytokines. Cell Signaling in press Sankary HN,
Yin DP, Chong AS, Ma LL, Blinder L, Shen JK, Foster P, Liu LP, Li C and
Williams JW (1999) The portosystemic shunt protects liver against ischemic
reperfusion injury. Transplantation 68 958-963 Sanlioglu AD, Koksal IT, Karacay B, Baykara M, Luleci G and Sanlioglu S (2006) Adenovirus-mediated IKKbKA expression sensitizes prostate carcinoma cells to TRAIL-induced apoptosis. Molecular Cancer Therapy 13 21-31 Sanlioglu S,
Luleci G and Thomas KW (2001) Simultaneous inhibition of Rac1 and IKK pathways
sensitizes lung cancer cells to TNFa-mediated apoptosis. Cancer Gene Therapy
Cancer Gene Therapy 8 897-905 Sanlioglu S,
Williams CM, Samavati L, Butler NS, Wang G, McCray PB, Jr., Ritchie TC,
Hunninghake GW, Zandi E and Engelhardt JF (2001) Lipopolysaccharide induces
Rac1-dependent reactive oxygen species formation and coordinates tumor
necrosis factor-alpha secretion through IKK regulation of NF-kB. Journal of
Biological Chemistry 276 30188-30198 Sanlioglu AD, Aydin C, Bozcuk H, Terzioglu E and Sanlioglu S (2004) Fundamental principals of tumor necrosis factor-alpha gene therapy approach and implications for patients with lung carcinoma. Lung Cancer 44 199-211 Sano C, Shimizu T and Tomioka H (2003) Effects of secretory leukocyte protease inhibitor on the tumor necrosis factor-alpha production and NF-kB activation of lipopolysaccharide-stimulated macrophages. Cytokine 21 38-42 Sano H, Kuronuma K, Kudo K, Mitsuzawa H, Sato M, Murakami S and Kuroki Y (2006) Regulation of inflammation and bacterial clearance by lung collectins. Respirology 11 S46-S50
Sano M,
Fujita H, Morita I, Uematsu H and Murota S (1999) Vitamin K2 (menatetrenone)
induces iNOS in bovine vascular smooth muscle cells: no relationship between
nitric oxide production and gamma-carboxylation. J Nutr Sci Vitaminol (Tokyo)
45 711-723 Sano M,
Fukuda K, Sato T, Kawaguchi H, Suematsu M, Matsuda S, Koyasu S, Matsui H,
Yamauchi-Takihara K, Harada M, Saito Y and Ogawa S (2001) ERK and p38 MAPK,
but not NF-kB, are critically involved in reactive oxygen species-mediated
induction of IL-6 by angiotensin II in cardiac fibroblasts. Circulation
Research 89 661-669 Santamaria A, Vazquez-Roman B, La Cruz VP, Gonzalez-Cortes C, Trejo-Solis MC, Galvan-Arzate S, Jara-Prado A, Guevara-Fonseca J and Ali SF (2005) Selenium reduces the proapoptotic signaling associated to NF-kB pathway and stimulates glutathione peroxidase activity during excitotoxic damage produced by quinolinate in rat corpus striatum. Synapse 58 258-266 Santana MA, Pedraza-Alva G, Olivares-Zavaleta N, Madrid-Marina V, HOrejsi V, Burakoff SJ and Rosenstein Y (2000) CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkB transcription factors in human T lymphocytes. Journal of Biological Chemistry 275 31460-31468 Santhi WS, Sebastian P, Varghese BT, Prakash O and Pillai MR (2006) NF-kB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins. Experimental and Molecular Pathology Santiago RA, Silva CA, Caparbo VF, Sallum AM and Pereira RM (2008) Bone mineral apparent density in juvenile dermatomyositis: the role of lean body mass and glucocorticoid use. Scandinavian Journal of Rheumatology 37 40-47 Santiago-Lomeli M, Gomez-Quiroz LE, Ortiz-Ortega VM, Kershenobich D and Gutierrez-Ruiz MC (2005) Differential effect of interleukin-10 on hepatocyte apoptosis. Life Sciences 76 2569-2579 Santilli G, Aronow BJ and Sala A (2003) Essential requirement of Apolipoprotein J (clusterin) signalling for IKB expression and regulation of NF-kB activity. Journal of Biological Chemistry 278 13422-13430 Santoro A, Majorana A, Bardellini E, Festa S, Sapelli P, Facchetti F (2003) NF-kappaB expression in oral and cutaneous lichen planus. Journal of Pathology 201 466-472 Santoro MG
(2000) Heat shock factors and the control of the stress response. Biochemical
Pharmacology 59 55-63 Santoro MG, Rossi A and Amici C (2003)
NF-kB and virus infection: who controls whom. EMBO Journal Santoro MM, Gaudino G and Marchisio PC (2003) The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration. Developmental Cell 5 257-271 Santoro MM< Samuel T, Mitchell T, Reed JC and Stainier DY (2007) Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis. Nature Genetics in press Santos M, Perez P, Segrelles C, Ruiz S, Jorcano JL and Paramio JM (2003) Impaired NF-kB activation and increased production of TNFa in transgenic mice expressing Keratin k10 in the basal layer of the epidermis. Journal of Biological Chemistry 278 13422-13430
Santos SC,
Monni R, Bouchaert I, Bernard O, Gisselbrecht S, Gouilleux F and
Penard-Lacronique V (2001) Involvement of the NF-kB pathway in the
transforming properties of the TEL-Jak2 leukemogenic fusion protein. FEBS
Letters 497 148-152 Santoso T
(2000) Improvement of endothelial dysfunction as a surrogate endpoint in the
treatment of hypertension. Current Hypertension Reports 2 227-229 Santos-Silva MC, Freitas MS and Assreuy J (2005) Involvement of NF-kB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells. Leukemia Research 30 145-152 Santos-Silva
MC, Sampaio de Freitas M and Assreuy J (2001) Killing of lymphoblastic
leukemia cells by nitric oxide and taxol: involvement of NF-kB activity.
Cancer Letters 173 53-61 Sanz AB, Justo P, Sanchez-Nino MD, Blanco-Colio LM, Winkles JA, Kretzler M, Jakubowski A, Blanco J, Egido J, Ruiz-Ortega M and Ortiz A (2008) The cytokine TWEAK modulates renal tubulointerstitial inflammation. Journal of the American Society of Nephrology in press Sanz L, Diaz-Meco
MT, Nakano H and Moscat J (2000) The atypical PKC-interacting protein p62
channels NF-kB activation by the IL-1-TRAF6 pathway. EMBO Journal 19 1576-1586 Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT and Moscat J (1999) The interaction of p62 with RIP links the atypical PKCs to NF-kB activation. EMBO Journal 18 3044-3053 Sanz-Rosa D, Cediel E, Heras Nde L, Miana M, Balfagon G, Lahera V, Cachofeiro VParticipation of aldosterone in the vascular inflammatory response of spontaneously hypertensive rats: role of the NFkB/IkB system. Journal of Hypertension 23 1167-1172 Sanz-Rosa D, Oubina MP, Cediel E, De Las Heras N, Vegazo O, Jimenez J, Lahera V and Cachofeiro V (2005) Effect of At1 recetpor antagonism on vascular and circulating inflammatory mediators in SHR: role of NF-kB/IkB system. American Journal of Physiology: Heart and Circulatory Physiology 288 H111-H115 Sapir T and Shoenfeld Y (2005) Uncovering the hidden potential of intravenous immunoglobulin as an anticancer therapy. Clinical Reviews in Allergy & Immunology 29 307-310 Sapountzi V, Logan IR and Robson CN (2006) Cellular functions of TIP60. International Journal of Biochemisitry & Cell Biology 38 1496-1509 Sappey C,
Boelaert JR, Legrand-Poels S, Forceille C, Favier A and Piette J (1995) Iron
chelation decreases NF-kB and HIV type 1 activation due to oxidative stress.
AIDS Research and Human Retroviruses 11 1049-1061 Sappington RM and Calkins DJ (2006) Pressure-induced regulation of IL-6 in retinal glial cells: involvement of the ubiquitin/proteasome pathway and NFkB. Investigative Ophthalmology & Visual Science 47 3860-3869 Sarchielli P, Floridi A, Mancini M, Rossi C, Coppola F, Baldi A, Pini L and Calbresis P (2006) NF-kB activity and iNOS expression in monocytes from internal jugular blood of migraine without aura patients during attacks. Cephalalgia 26 1071-1079 Sarady JK, Otterbein SL, Liu F, Otterbein LE and Choi AM (2002) Carbon monoxide modulates endotoxin-induced production of granulocyte macrophage colony-stimulating factor in macrophages. Am J Respir Cell Mol Biol 27 739-745 Saraiva M, Christensen JR, Tsytsykova AV, Goldfeld AE, Ley SC, Kioussis D and O' Garra A (2005) Identification of a macrophage-specific chromatin signature in the IL-10 locus. Journal of Immunology 175 1041-10466 Saraswathi V, Wu G, Toborek M and Hennig B (2004) Linoleic acid-induced endothelial activation: role of calcium and peroxynitrite signaling. Journal of Lipid Research 45 794-804 Sardi SP, Rey-Ares V, Pujol-Lereis VA, Serrano SA and Rothlin RP (2002) Further pharmacological evidence of nuclear factor-kB pathway involvement in bradykinin B1 receptor-sensitized responses in human umbilical vein. J Pharmacol Exp Ther 301 975-980 Sareila O, Hamalainen M, Nissinen E, Kankaanranta H and Moilanen E (2007) Orazipone inhibits activation of inflammatory transcription factors NF-kB and STAT1 and decreases inducible nitric oxide synthase expression and nitric oxide production in response to inflammatory stimuli. Journal of Pharmacology and Experimental Therapy in press Sareneva T,
Julkunen I and Matikainen S (2000) IFN-a and IL-12 induce IL-18 receptor
gene expression in human NK and T cells. Journal of Immunology 165 1933-1938 Sarkar A, Duncan M, Hart J, Hertlein E, Guttridge DC and Wewers MD (2006) ASC directs NF-kB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions. Journal of Immunology 176 4979-4986 Sarkar A, Meila M and Franza RB (2007) IkB, NF-kB regulation model: simulation analysis of small number of molecules. EURASIP Journal of Bioinformatic Systems Biology 2007 25250 Sarkar A, Sreenivasan Y and Manna SK (2003) alpha-Melanocyte-stimulating hormone induces cell death in mast cells: involvement of NF-kB. FEBS Letters 549 87-93 Sarkar A, Sreenivasan Y, Ramesh GT and Manna SK (2004) Beta-D-glucoside suppresses TNF-induced activation of nuclear transcription factor kB but potentiates apoptosis. Journal of Biological Chemistry 279 33768-33781 Sarkar D and Fisher PB (2006) Molecular mechanisms of aging-associated inflammation. Cancer Letters 236 13-23 Sarkar D, Lebedeva IV, Emdad L, Kang DC, Baldwin AS Jr and Fisher PB (2004) Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation. Cancer Research 64 7473-7478 Sarkar D, Park ES, Emdad L, Lee SG, Su ZZ and Fisher PB (2008) Molecular basis of nuclear factor-kB activation by astrocyte elevated gene-1. Cancer Research 68 1478-1484 Sarkar D, Saha P, Gamre S, Bhattacharjee S, Hariharan C, Ganguly S, Sen R, Mandal G, Chattopadhyay S, Majumdar S adn Chatterjee M (2008) Anti-inflammatory effect of allylpyrocatechol in LPS-induced macrophages is mediated by suppression of iNOS and COX-2 via the NF-kB pathway. International Immunopharmacology 8 1264-1271 Sarkar FH, Adsule S, Li Y and Padhye S (2007) Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy. Mini Reviews in Medicinal Chemistry 7 599-608 Sarkar FH, Adsule S, Padhye S, Kulkarni S and Li Y (2006) The role of genistein and synthetic derivatives of isoflavone in cancer prevention and therapy. Mini Reviews in Medicinal Chemsitry 6 401-407 Sarkar FH, Banerjee S and Li Y (2006) Pancreatic cancer: pathogenesis, prevention and treatment. Toxicology and Applied Pharmacology in press Sarkar FH and Li Y (2002) Mechanisms of cancer chemoprevention by soy isoflavone genistein. Cancer Metastasis Rev 21 265-280 Sarkar FH and Li Y (2003) Soy isoflavones and cancer prevention. Cancer Investigation 21 744-757 Sarkar FH and Li Y (2004) Cell signaling pathways altered by natural chemopreventive agents. Mutation Research 555 53-64 Sarkar FH and Li Y (2004) Indole-3-carbinol and prostate cancer. Journal of Nutrition 134 3493S-3498S Sarkar FH and Li Y (2008) NF-kB: a potential target for cancer chemoprevention and therapy. Frontiers in Bioscience 13 2950-2959 Sarkar FH and Li YW (2007) Targeting multiple signal pathways by chemopreventive agents for cancer prevention and therapy. Acta Pharmacologica Sinica 28 1305-1315 Sarkar S and
Gilmore TD (1993) Transformation by the vRel oncoprotein requires sequences
carboxy-terminal to the Rel homology domain. Oncogene 8 2245-2252 Sarkar SN, Elco CP, Peters KL, Chattopadhyay S and Sen GC (2007) Two tyrosine residues of toll-like receptor 3 trigger different steps of NF-kB activation. Journal of Biological Chemistry 282 3423-3427 Sarma PK, Misra R and Aggarwal A (2007) Elevated serum receptor activator of NFkB ligand (RANKL), osteoprotegerin (OPG), matrix metalloproteinase (MMP)3, and ProMMP1 in patients with juvenile idiopathic arthritis. Clinical Rheumatology in press Sarma V, Lin
Z, Rust BM, Tewari M, Noelle RJ and Dixit VM (1995) Activation of the B-cell
surface receptor CD40 induces A20, a novel zinc finger protein that inhibits
apoptosis. Journal of Biological Chemistry 270 12343-12346 Sarman B, Skoumal R, Leskinen H, Rysa J, Ilves M, Soini Y, Tuukkanen J, Pikkarainen S< Lako-Futo Z< Sarman B, Papp L, Dechatel R, Toth M, Ruskoaho H and Szokodi I (2007) Nuclear factor-kappaB signaling contributes to severe, but not moderate, angiotensin II-induced left ventricular remodeling. Journal of Hypertension 25 1927-1939 Sarmiento UM,
Perez JR, Becker JM and Narayanan R (1994) In vivo toxicological effects of
relA antisense phosphorothioates in CD-1 mice. Antisense Research and Development 4 99-107 Sarnico I, Boroni F, Benarese M, Alghisi M, Valerio A, Battistin L, Spano P and Pizzi M (20080 Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. Journal of Neural Transmission inp ress Sarnico I, Boroni F, Benarese M, Sigala S, Lanzillotta A, Battistin L, Spano P and Pizzi M (2007) Activation of NF-kB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells. Journal of Neural Transmission in press Sartor CI
(2002) Molecular targets as therapeutic strategies in the management of breast
cancer. Seminars in Radiation Oncology 12 341-351 Sartor RB (2003) Targeting enteric bacteria in treatment of inflammatory bowel diseases: why, how, and when. Current Opinion in Gastroenterology 19 358-365 Sartore-Bianchi A, Gasparri F, Galvani A, Nici L, Darnowski JW, Barbone D, Fennell DA, Gaudino G, POrta C and Mutti L (2007) Bortezomib inhibits nuclear factor-kB dependent survival and has potent in vivo activity in mesothelioma. Clinical Cancer Research 13 5942-5951 Sasai M, Oshiumi H, Matsumoto M, Inoue N, Fujita F, Nakanishi M and Seya T (2005) NF-kB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation. Journal of Immunology 174 27-30 Sasai M, Matsumoto M and Seya T (2006) The kinase complex responsible for IRF-3-mediated IFN-beta production in myeloid dendritic cells (mDC). Journal of Biochemistry (Tokyo) 139 171-175 Sasaki CY, Barberi TJ, Ghosh P and Longo DL (2005) Phosphorylation of RelA/p65 on serine 536 defines an IkBa-independent NF-kB pathway. Journal of Biological Chemistry 280 34538-34547 Sasaki CY, Slemenda CF, Ghosh P, Barberi TJ and Longo DL (2007) Traf1 induction and protection from tumor necrosis factor by nuclear factor-kB p65 is independent of serine 536 phosphorylation. Cancer Research 67 11218-11225 Sasaki H, Ray PS, Zhu L, Otani H, Asahara T and Maulik N (2001) Hypoxia/reoxygenation promotes myocardial angiogenesis via an NF -kB-dependent mechanism in a rat model of chronic myocardial infarction. Journal of Molecular and Cellular Cardiology 33 283-294 Sasaki K, Iizuka M, Konno S, Shindo K, Sato A, Horie Y and Watanabe S (2005) Ecabet sodium prevents the delay of wound repair in intestinal epithelial cells induced by hydrogen peroxide. Journal of Gastroenterology 40 474-482 Sasaki K, Taniguchi M, Miyoshi M, Goto O, Sato K and Watanabe T (2005) Are transcription factors (NF-kB and AP-1) involved in the angiotensin II-stimulated production of proinflammatory cytokines induced by LPS in dehydrated rats? Am J Physiol Regul Integr Comp Physiol in press Sasaki M,
Jordan P, Joh T, Itoh M, Jenkins M, Pavlick K, Minagar A and Alexander SJ
(2002) Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition
of NF-kB. BMC Gastroenterol 2 9. Sasaki M, Jordan P, Welbourne T, Minagar A, Joh T, Ando T, Elrod J and Alexander JS (2005) Troglitazone, a PPAR-gamma activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-alpha. BMC Physiol 5 3 Sasaki N,
Morisaki T, Hashizume K, Yao T, Tsuneyoshi M, Noshiro H, Nakamura K, Yamanaka
T, Uchiyama A, Tanaka M and Katano M (2001) Nuclear factor-kB p65 (RelA)
transcription factor is constitutively activated in human gastric carcinoma
tissue. Clinical Cancer Research 7 4136-4142 Sasaki S, Osanai T, Tomita H, Matsunaga T, Magota K and Okumura K (2004) Tumor necrosis factor alpha as an endogenous stimulator for circulating coupling factor 6. Cardiovascular Research 6 578-586 Sasaki T and
Koyama H (1989) Characterisation of cell lines transformed in vivo and in
vitro by reticuloendotheliosis virus strain T. Avian Pathology 18 307-319 Sasaki T, Takahshi T, Maeshima K, Shimizu H, Toda Y, Morimatsu H, Takeuchi M, Yokoyama M, Akagi R and Morita K (2006) Heme arginate pretreatment attenuates pulmonary NF-kB and AP-1 activation induced by hemorrhagic shock via heme oxygenase-1 induction. Medicinal Chemistry 2 271-274 Sasaki Y, Calado DP, Derudder E, Zhang B, Shimizu Y, Mackay F, Nishikawa S, Rajewsky K and Schmit-Supprian M (2008) NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells. Proceedings of the National Academy of Sciences USA 105 10883-10088 Sasaki Y, Derudder E, Hobeika E, Pelanda R, Reth M, Rajewsky K and Schmidt-Supprian M (20060 Canonical NF-kB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation. Immunity 24 729-739 Sasamoto A, Nagino M, Kobayashi S, Naruse K, Nimura Y and Sokabe M (2005) Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uni-axial continuous stretch. Am J Physiol Cell Physiol 288 C1012-C1022 Sasahira T, Kirita T, Oue N, Bhawal UK, Yamamoto K, Fujii K, Ohmori H, Luo Y, Yasui W, Bosserhoff AK and Kunyasu H (2008) High mobility group box-1-inducible melanoma inhibitory activity is associated with nodal metastasis and lymphangiogenesis in oral squamous cell carcinoma. Cancer Sceince in press Sasuga Y, Tani T, Hayashi M, Yamakawa H, Ohara O and Harada Y (2006) Development of a microscopic platform for real-time monitoring of biomolecular interactions. Genome Research 16 132-139 Satake S, Nagaki M,Kimura K and Moriwaki H (2007) Inhibition of nuclear factor-kappa B induces inflammatory cell migration and exacerbates severe liver injury in hepatitis B virus transgenic mice. Hepatology Research 37 524-530 Sater R
(1994) Basal expression of the human macrophage colony-stimulating factor (M-CSF)
gene in K562 cells. Leukemia Research 8 133-143 Sathe SS, Sizemore N, Li X, Vithalani K, Commane M, Swiatkowski SM and Stark GR (2003) Mutant human cells with constitutive activation of NF-kB. Proceedings of the National Academy of Scineces USA 101 192-197 Sato A, Iizuka M, Nakagomi O, Suzuki M, Horie Y, Konno S, Hirawawa F, Sasaki K, SHindo K and Watanabe S (2006) Rotavirus double-stranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells. Journal of Gastroenterology and Hepatology 21 521-530 Sato
A, Oya M, Ito K, Mizuno R, Horiguchi T, Umezawa K, Hayakawa M and Murai M
(2006) Survivin associates with cell proliferation in renal cancer cells:
Regulation of survivin expression by insulin-like growth factor-1,
interferon-gamma and a novel NF-kappaB inhibitor. Sato H,
Kuriyama-Matsumura K, Hashimoto T, Sasaki H, Wang H, Ishii T, Mann GE and
Bannai S (2001) Effect of oxygen on induction of the cystine transporter by
bacterial lipopolysaccharide in mouse peritoneal macrophages. Journal of
Biological Chemistry 276 10407-10412 Sato H, Lagan AL, Alexopoulou C, Vassilakis DA, Ahmad T, Pantelidis P, Veeraraghavan S, Renzoni E, Denton C, Black C, Wells AU, Du Bois RM and Welsh KI (2004) The TNF-863A allele strongly associates with anticentromere antibody positivity in scleroderma. Arthritis & Rheumatism 50 558-564 Sato H, Watanabe A, Tanaka T, Koitabashi N, Arai M, Kurabayashi M and Yokoyama T (2003) Regulation of the human tumor necrosis factor-alpha promoter by angiotensin II and lipopolysaccharide in cardiac fibroblasts: different cis-acting promoter sequences and transcriptional factors. Journal of Cellular and Molecular Cardiology 35 1197-1205 Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H and Takyanagi H (2006) Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nature Medicine 12 1410-1416 Sato K, Taniguchi T, Suzuki M, Shinohara F, Takada H and Rikiishi H (2003) Dual role of NF-kB in apoptosis of THP-1 cells during treatment with etoposide and lipopolysaccharide. Leukemia Research 28 63-69 Sato K, Yang XL, Yudate T, Chung JS, Wu J, Luby-Phelps K, Kimberly RP, Underhill D, Cruz Jr PD and Ariizumi K (2006) Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses. Journal of Biological Chemistry in press Sato M, Ogihara K, Sawahata R, Sekikawa K and Kitani H (2007) Impaired LPS-induced signaling in microglia overexpressing the Wiskott Aldrich syndrome protein N-terminal domain. International Immunology 19 901-911 Sato M, Sano H, Iwaki D, Kudo K, Konishi M, Takahashi H, Takahashi T, Imaizumi H, Asai Y, Kuroki Y (2003) Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kB activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A. Journal of Immunology 171 417-425 Sato N, Moore FA, Smith MA, Zou L, Moore-Olufemi S, Schultz SG and Kozar RA (2005) Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion. Journal of Trauma 58 455-461 Sato S, Futakuchi M, Ogawa K, Asamoto M, Nakao K, Asai K and Shirai T (2008) Transforming growth factor beta derived from bone matrix promotes cell proliferation of prostate cancer and osteoclast activation-associated osteolysis in the bone microenvironment. Cancer Science 99 316-323 Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Matusmoto K, Takeuchi O and Akira S (2006) Essential function for the kinase TAK1 in innate and adaptive immune responses. Nature Immunology 7 962-970 Sato S, Sanjo H, Tsujimura T, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Takeuchi O and Akira S (2006) TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells. International Immunology in press Sato S, Sugiyama M, Yamamoto M, Watanabe Y, Kawai T, Takeda K and Akira S (2003) Toll/IL-1 Receptor Domain-Containing adaptor inducing IFN-b (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates Two Distinct transcription factors, NF-kB and IFN-regulatory factor-3, in the Toll-like receptor signaling. Journal of Immunology 171 4304-4310 Sato T, Odagiri H, Ikenaga SK, Maruyama M and Sasaki M (2003) Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkBa super-repressor. Cancer Science 94 467-472 Sato Y, SHibata K, Kataoka H, Ogino S, Bunshi F, Yokoyama A, Tamura K, Akasaka T, Uo M, MOtomiya K, Jeyadevan B, Hatakeyma R, Watari F and Tohji K (2005) Strict preparation and evaluation of water-soluble hat-stacked carbon nanofibers for biomedical application and their high biocompatibility: influence of nanofiber-surface functional groups on cytotoxicity. Molecular Biosystems 1 142-145 Sato Y, Kato J, Takimoto R, Takada K, Kawano Y, Miyanishi K, Kobune M, Sato Y, Takayama T, Matsunaga T and Niitsu Y (2006) Hepatitis C virus core protein promotes proliferation of human hepatoma cells through enhancement of transforming growth factor-{alpha} expression via activation of NF-kB. Gut in press Satoh A, Gukovskaya AS, Edderkaoui M, Daghighian MS, Reeve jr JR, Shimosegawa T and Pandol SJ (2005) Tumor necrosis factor-a mediates pancreatitis responses in acinar cells via protein kinase C and proline-rich tyrosine kinase 2. Gastroenterology 129 629-651 Satoh A, Gukovskaya AS, Nieto JM, Cheng JH, Gukovsky I, Reeve Jr JR, Shimosegawa T and Pandol SJ (2004) PKC delta and epsilon regulate NF-kB activation induced by cholecystokinin and TNF-{alpha} in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol 287 G582-G591 Satoh A, Gukovskaya A, Reeve Jr JR, Shimosegawa T and Pandol SJ (2006) Ethanol sensitizes NF-kB activation in pancreatic acinar cells through effects on protein kinase C epsilon. American Jounral of Physiology: Gastrointestinal and Liver Physiology in press Satoh A, Masamune A, Kimura K, Kaneko K, Sakai Y, Yamagiwa T, Satoh M, Kikuta K, Asakura T, Shimosegawa T (2003) Nuclear factor kB expression in peripheral blood mononuclear cells of patients with acute pancreatitis. Pancreas 26 350-356
Satoh A,
Shimosegawa T, Fujita M, Kimura K, Masamune A, Koizumi M and Toyota T (1999)
Inhibition of nuclear factor-kB activation improves the survival of rats with
taurocholate pancreatitis. Gut 44 253-258 Satoh A,
Shimosegawa T, Masamune A, Fujita M, Koizumi M and Toyota T (1999) Ascitic
fluid of experimental severe acute pancreatitis modulates the function of
peritoneal macrophages. Pancreas 19 268-275 Satoh A, Yokozawa T, Kim YA, Cho EJ, Okamoto T and Sei Y (2005) The mechanisms underlying the anti-aging activity of the Chinese prescription Kangen-karyu in hydrogen peroxide-induced human fibroblasts. J Pharm Pharamacol 57 1335-1344 Satoh JI, Illes Z, Peterfalvi A, Tabunoki H, Rozsa C and Yamamura T (2007) Aberrant transcriptional regulatory network in T cells of multiple sclerosis. Neuroscience Letters in press Satoh JI, Obayashi S, Misawa T, Tabunoki H, Yamamura T, Arima K and Konno H (2008) Neuromyelitis optica/Devic's disease: Gene expression profiling of brain lesions. Neuropathology in press Satoh M,
Kashihara N, Yamasaki Y, Maruyama K, Okamoto K, Maeshima Y, Sugiyama H, Sugaya
T, Murakami K and Makino H (2001) Renal interstitial fibrosis is reduced in
angiotensin II type 1a receptor-deficient mice. Journal of the American
Society of Nephrology 12 317-325 Satou R, Gonzalez-Villalobos RA, Miyata K, Ohashi N, Katsurada A, Navar LG and Kobori H (2008) Co-stimulation with angiotensin II and interleukin 6 augments angiotensinogen expression in cultured human renal proximal tubular cells. American Journal of Physiology: Renal Physiology in press Satou Y, Nosaka K, Koya Y, Yasunaga JI, Toyokuni S and Matsuoka M (2004) Proteasome inhibitor, bortezomib, potently inhibits the growth of adult T-cell leukemia cells both in vivo and in vitro. Leukemia 18 1357-1363 Satriano J and Schlondorff D (1994) Activation and attenuation of transcription factor NF-kB in mouse glomerular mesangial cells in response to tumor necrosis factor-a, immunoglobulin G, and adenosine 3’:5’-cyclic monophosphate. Journal of Clinical Investigation 94 1629-1636 Satsu H, Ishimoto Y, Nakano T, Mochizuki T, Iwanaga T and Shimizu M (2006) Induction by activated macrophage-like THP-1 cells of apoptotic and necrotic cell death in intestinal epithelial Caco-2 monolayers via tumor necrosis factor-alpha. Experimental Cell Research in press Satta N, Dunoyer-Geindre S, Reber G, Fish RJ, Boehlen F, Kruithof EK and de Moerloose P (2006) The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood in press Satterwhite
E, Sonoki T, Willis
TG, Harder L, Nowak R, Arriola EL, Liu H, Price HP, Gesk S, Steinemann D,
Schlegelberger B, Oscier DG, Siebert R, Tucker PW and Dyer MJ (2001) The BCL11
gene family: involvement of BCL11A in lymphoid malignancies. Blood 98
3413-3420 Sattler KJ, Woodrum JE, Galili O, Olson M, Samee S, Meyer FB, Zhu XY, Lerman LO and Lerman A (2004) Concurrent treatment with renin-angiotensin system blockers and acetylsalicylic acid reduces nuclear factor kB activation and C-reactive protein expression in human carotid artery plaques. Stroke 36 14-20 Satyamoorthy
K, Li G, Vaidya B, Kalabis J and Herlyn M (2002) Insulin-like growth
factor-I-induced migration of melanoma cells is mediated by interleukin-8
induction. Cell Growth & Differentiation 13 87-93 Sau K, Mambula SS, Latz E, Henneke P, Golenbock DT and Levitz SM (2003) The antifungal drug amphotericin B promotes inflammatory cytokine release by a toll-like receptor and CD14-dependent mechanism. Journal of Biological Chemistry 278 37561-37568 Sauer H, Neukirchen W, Rahimi G, Grunheck F, Hescheler J and Wartenberg M (2004) Involvement of reactive oxygen species in cardiotrophin-1-induced proliferation of cardiomyocytes differentiated from murine embryonic stem cells. Experimental Cell Research 294 313-324
Sauer H,
Rahimi G, Hescheler J and Wartenberg M (1999) Effects of electrical fields on
cardiomyocyte differentiation of embryonic stem cells. Journal of Cellular
Biochemistry 75 710-723 Saura J, Petegnief V, Wu X, Liang Y and Paul SM (2003) Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide. Journal of Neurochemistry 85 1455-1467 Saura J, Tusell JM and Serratosa J (2003) High-yield isolation of murine microglia by mild trypsinization. Glia 44 183-189
Saura M,
Zaragoza C, Bao C, McMillan A and Lowenstein CJ (1999) Interaction of
interferon regulatory factor-1 and nuclear factor kappaB during activation of
inducible nitric oxide synthase transcription. Journal of Molecular Biology
289 459-471 Saurabh S, Reddy MA, Wong C, Meng L, Wang M and Natarajan R (2007) Cooperation of SRC-1 and p300 with NF-kB and CREB in angiotensin II-induced IL-6 expression in vascular smooth muscle cells. Arterioscleroosis, Thrombosis, and Vascular Biology in press Savage KJ, Monti S, Kutok JL, Cattoretti G, Neuberg D, De Leval L, Kurtin P, Dal Cin P, Ladd C, Feuerhake F, Aguiar RC, Li S, Salles G, Berger F, Jing W, Pinkus GS, Habermann T, Dalla-Favera R, Harris NL, Aster JC, Golub TR and Shipp MA (2003) The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin's lymphoma. Blood 102 3871-3879 Savaskan NE, Brauer AU, Kuhbacher M, Eyupoglu IY, Kyriakopoulos A, Ninnemann O, Behne D and Nitsch R (2003) Selenium deficiency increases susceptibility to glutamate-induced excitotoxicity. FASEB Journal 17 112-114 Savedra Jr R,
Delude RL, Ingalls RR, Fenton MJ and Golenbock DT (1996) Mycobacterial
lipoarabinomannan recognition requires a receptor that shares components of
the endotoxin signaling system. Journal of Immunology Savickiene J, Borutinskaite VV, Treigyte G, Magnusson KE and Navakauskiene R (2006) The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines. European Journal of Pharmacology in press Savickience J, Treigyte G, Borutinskaite V, Navakauskience R, and Magnusson KE (2006) The Histone deacetylase inhibitor FK228 distinctly sensitizes the human leukemia cells to retinoic acid-induced differentiation. Annals of the New York Academy of Sciences 1091 368-384 Savickiene J, Treigyte G, Pivoriunas A, Navakauskiene R and Magnusson KE (2004) Sp1 and NF-kB transcription factor activity in the regulation of the p21 and FasL promoters during Promyelocytic leukemia cell monocytic differentiation and its associated apoptosis. Annals of the New York Academy of Sciences 1030 569-577 Saviaon S, Sofer M, Brengauz-Breitmann M Fein AS Torchinsky A and Toder V (2007) NF-kB regulates the response of embryonic cells to heat shock. International Journal of Hyperthermiaia 23 277-286 Savkovic SD, Koutsouris A and Hecht G (2003) PKC{zeta} participates in activation of inflammatory response induced by enteropathogenic E. coli. American Journal of Physiology: Cell Physiology 285 C512-C521 Savkovic SD, Ramaswamy A, Koutsouris A and Hecht G (2001) EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruption. American Journal of Physiology: Gastrointestinal and Liver Physiology 281 G890-G898 Savkovic V, Gantzer H, Reiser U Selig L, Gaiser S, Sack U, Kloppel G, MOssner J, Keim V, Horn F and Bodeker H (2007) Clusterin is protective in pancreatitis through anti-apoptotic and anti-inflammatory properties. Biochemical and Biophysical Research Communications in press Savli H, Szendr A, Romics I and Nagy B (2008) Gene network and canonical pathway analysis in prostate cancer: a microarray study. Experimental and Molecular Medicine 40 176-185 Savoia C and Schiffrin EL (2007) Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions. Clinical Science (London) 112 375-384 Savolainen
KM, Loikkanen J, Eerikainen S and Naarala J (1998) Interactions of excitatory
neurotransmitters and xenobiotics in excitotoxicity and oxidative stress:
glutamate and lead. Toxicology Letters 102-103 363-367 Savransky V, Nanayakkara A, Vivero A, Li J, Bevans S, Smith PL, Torgenson MS and Polotsky VY (2007) Chronic intermittent hypoxia predisposes to liver injury. Hepatology 45 1007-1013 Sawa Y, Morishita R, Suzuki K, Kagisaki K, Kaneda Y, Maeda K, Kadoba K and Matsuda H (1997) A novel strategy for myocardial protection using in vivo transfection of cis element 'decoy' against NFkB binding site: evidence for a role of NFkB in ischemia-reperfusion injury. Circulation 96 280-284 Sawa Y, Ueki T, Hata M, Kana I, Tsuruga E, Kojima H, Ishikawa H and Yoshida S (2007) LPS-induced IL-6, IL-8, VCAM-1, and ICAM-1 expression in human lymphatic endothelium. Journal of Histochemistry and Cytochemistry in press Sawada H, Mitani Y, Maruyama J, Jiang BH, Ikeyama Y, Dida FA, Yamamoto H, Imanaka-Yoshida K, Shimpo H, Mizoguchi A, Maruyama K and Komada Y (2007) A nuclear factor-kB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats. Chest 132 1265-1274 Sawada N, Ogawa T, Asai Y, Makimura Y and Sugiyama A (2007) Toll-like receptor 4-dependent recognition of structurally different forms of chemically synthesized lipid As of Porphyromonas gingivalis. Clinical and Experimental Immunology in press Sawai H, Funahashi H, Okada Y, Matsuo Y, Sakamoto M, Yamamoto M, Takeyama H and Manabe T (2005) Interleukin-1a enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells. Medical Science Monitor 11 BR343-B350 Sawano H, Haneda M, Sugimoto T, Inoki K, Koya D and Kikkawa R (2002) 15-Deoxy-Delta12,14-prostaglandin J2 inhibits IL-1beta-induced cyclooxygenase-2 expression in mesangial cells. Kidney International 61 1957-1967 Sawhney M, Rohatgi N, Kaur J, Shishodia S, Sethi G, Gupta SD, Deo SV, Shukla NK< Aggarwal BB and Ralhan R (2007) Expression of NF-kB parallels COX-2 expression in oral precancer and cancer: Association with smokeless tobacco. International Journal of Cancer in press Sawicki G, Dakour J and Morrish DW (2003) Functional proteomics of neurokinin B in the placenta indicates a novel role in regulating cytotrophoblast antioxidant defences. Proteomics 3 2044-2051 Sawyer RT, Fontenot AP, Barnes TA, Parsons CE, Tooker BC, Maier LA, Gillespie MM, Gottschall EB, Silveira L, Hagman J and Newman LS (2007) Beryllium-induced TNF-a production is transcription-dependent in chronic beryllium disease. American Journal of Respiratory Cell and Molecular Biology 36 191-200 Sayed AA (2008) Thymoquinone protects renal tubular cells against tubular injury. Cell Biochem Funct in press Sayed AA and Morcos M (2007) Thymoquinone decreases AGE-induced NF-kB activation in proximal tubular epithelial cells. Phytotherapy Research in press Sayegh CE,
Rao MA and Ratcliffe MJ (1999) Avian B cell development: lessons from
transgenic models. Veterinary Immunology and Immunopathology 72 31-37 Sayers TJ, Brooks AD, Koh CY, Ma W, Seki N, Raziuddin A, Blazar BR, Zhang X, Elliott PJ and Murphy WJ (2003) The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP. Blood 102 303-310 Scadding G (2005) Predicting and establishing the clinical efficacy of a histamine h(1)-receptor antagonist: desloratadine, the model paradigm. Clinical Drug Investigation 25 153-164
Scala G,
Quinto I, Ruocco MR, Mallardo M, Ambrosino C, Squitieri B, Tassone P and
Venuta S (1993) Epstein-Barr virus nuclear antigen 2 transactivates the long
terminal repeat of human immunodeficiency virus type 1. Journal of Virology 67
2853-2861 Scalabrino G, Veber D and Mutti E (2008) Experimental and clinical evidence of the role of cytokines and growth factors in the pathogenesis of acquired cobalamin-deficient leukoneuropathy. Brain Research Reviews in press Scarfi S, Benatti U, Pozzolini M, Clavarino E, Ferrais C, Magnone M, Valisano L and Giovine m (2007) Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages. FEBS Journal 274 60-73 Scarim AL,
Heitmeier MR and Corbett JA (1998) Heat shock inhibits cytokine-induced nitric
oxide synthase expression by rat and human islets. Endocrinology 139 5050-5057 Scata KA and El-Deiry WS (2006) Taming NEMO to slay cancer cells. Cancer Biology & Therapy in press Scatena M and
Giachelli C (2002) The alpha(v)beta3 integrin, NF-kB, osteoprotegerin
endothelial cell survival pathway. Potential role in angiogenesis. Trends in
Cardiovascular Medicine 12 83-88 Scatena M,
Almeida M, Chaisson ML, Fausto N, Micosia RF and Giachelli CM (1998) NF-kB
mediates ab3 integrin-induced endothelial cell survival. Journal of Cell
Biology 141 1083-1093 Schaaf MJ and Cidlowski JA (2002) Molecular mechanisms of glucocorticoid action and resistance. Journal of Steroid Biochemistry and Molecular Biology 83 37-48 Schaaf MJM, Willetts L, Hayes BP, Maschera B, Stylianou E and Farrow SN (2006) The relationship between intranuclear mobility of the NF-kB subunit p65 and its DNA-binding affinity. Journal of Biological Chemistry 281 22409-22420 Schabbauer B, Luyendyk J, Crozat K, Jiang Z, Mackman N, Bahram S and Georgel P (20080 TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages. Molecular Immunology in press Schachter AD, Strehlau J, Zurakowski D, Vasconcellos L, Kim YS, Zheng XX, Gunshin Y, Overstreet SL, Benfield MR, Tejani A, Harmon WE, Herrin JT and Strom TB (2000) Increased nuclear factor-kappaB and angiotensinogen gene expression in posttransplant recurrent focal segmental glomerulosclerosis. Transplantation 70 1107-1110
Schachter AD
and Strom TB (1999) Posttransplant recurrent FSGS: molecular insights and
future directions. Nephron 82 300-305 Schacke H, Rehwinkel H, Asadullah K and Cato AC (2006) Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index. Experimental Dermatology 15 565-573 Schaecher K, Goust JM and Banik NL (2004) The effects of calpain inhibition on IkB alpha degradation after activation of PBMCs: identification of the calpain cleavage sites. Neurochem Res 29 1443-1451 Schaefer BC, Kappler JW, Kupfer A and Marrack P (2004) Complex and dynamic redistribution of NF-kB signaling intermediates in response to T cell receptor stimulation. Proceedings of the National Academy of Sciences USA 101 1004-1009 Schaefer KL, Denevich S, Ma C, Cooley SR, Nakajima A, Wada K, Schlezinger J, Sherr D and Saubermann LJ (2005) Intestinal intiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms. Inflammatory Bowel Disease 11 244-252 Schaefer L, Babelova A, Kiss E, Hausser HJ, Baliova M, Krzyzankova M, Marsche G, Young MF, Mihalik D, Gotte M, Malle E, Schaefer RM and Grone HJ (2005) The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. Journal of Clinical Investigation 115 2223-2233 Schaeffler A, Gross P, Buettner R, Bollheimer C, Buechler C, Neumeier M, Kpp A , Schoelmerich J and Falk W (2008) Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity. Immunology in press Schaeffer AJ, Klumpp DJ, Weiser AC, Sengupta S, Forrestal SG and Batler RA (2004) Infectious response to E. coli: molecular and genetic pathways. International Journal of Antimicrobial Agents 24 57-60
Schafer H,
Arlt A, Trauzold A, Hunermann-Jansen A and Schmidt WE (1999) The putative
apoptosis inhibitor IEX-1L is a mutant nonspliced variant of p22(PRG1/IEX-1)
and is not expressed in vivo. Biochemical and Biophysical Research
Communications 262 139-145 Schafer H,
Diebel J, Arlt A, Trauzold A and Schmidt WE (1998) The promoter of human p22/PACAP
response gene 1 (PRG1) contains functional binding sites for the p53 tumor
suppressor and for NFkB. FEBS Letters 436 139-143 Schafer R, Sedehizade F, Welte T and Reiser G (2003) ATP and UTP-activated P2Y receptors differently regulate proliferation of human lung epithelial tumor cells. Am J Physiol Lung Cell Mol Physiol Schafer SL,
Hiscott J and Pitha PM (1996) Differential regulation of the HIV-1 LTR by
specific NF-kB subunits in HSV-1-infected cells. Virology 224 214-223 Schaffer A,
Cerutti A, Shah S, Zan H and Casali P (1999) The evolutionarily conserved
sequence upstream of the human Ig heavy chain S gamma 3 region is an inducible
promoter: synergistic activation by CD40 ligand and IL-4 via cooperative NF-kB and STAT-6 binding sites. Journal of Immunology 162 5327-5336 Schapansky
J, Olson K, Van Der Ploeg R and Glazner G (2007) NF-kB activated by ER calcium
release inhibits Abeta-mediated expression of CHOP protein: enhancement by
AD-linked mutant presenilin 1. Scharschmidt E, Wegener E, Heissmeyer V, Rao A and Krappmann D (2004) Degradation of bcl10 induced by T-cell activation negatively regulates NF-kB signaling. Molecular and Cellular Bioliology 24 3860-3873 Schat KA,
Pratt WD, Morgan R, Weinstock D and Calnek BW (1992) Stable transfection of
reticuloendotheliosis virus-transformed lymphoblastoid cell lines. Avian
Diseases 36 432-439 Schattner EJ (2000) CD40 ligand in CLL pathogenesis and therapy. Leukemia and Lymphoma 37 461-472 Schatzle JD,
Kralova J and Bose Jr HR (1995) Avian IkBa is transcriptionally induced by
c-Rel and v-Rel with different kinetics. Journal of Virology 69 5383-5390 Schauer SL,
Wang Z, Sonenshein GE and Rothstein TL (1996) Maintenance of Nuclear Factor-kB
and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from
receptor-mediated apoptosis through modulation of IkB proteins. Journal of
Immunology 157 81-86 Schauvliege
R, Vanrobaeys J, Schotte P and Beyaert R (2002) Caspase-11 gene expression in
response to LPS and IFN-gamma requires NF-kB and STAT1. Journal of Biological
Chemistry 277 41624-41630 Schavinsky-Kharapunsky Y, Priel E and Aboud M (2007) Dose-dependent dual effect of HTLV-1 Tax oncoprotein on p53-dependent nucleotide excision repair in human T-cells. International Journal of Cancer in press Schawalder A,
Oertli B, Beck-Schimmer B and Wuthrich RP (1999) Regulation of
hyaluronan-stimulated VCAM-1 expression in murine renal tubular epithelial
cells. Nephrol Dial Transplant 14 2130-2136 Schedel M, Carr D, Klopp N, Woitsch B, Illig T, Stachel D, Schmid I, Fritzsch C, Weiland SK, Von Mutius E and Kabesch M (2004) A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels. Journal of Allergy and Clinical Immunology 114 1100-1105 Schedel M, Pinto LA, Schaub B, Rosenstiel P, Cherkasov C, Cameron L, Klopp N, Illig T, Vogelberg C, Weiland SK, von Mutius E, Lohoff M and Kabesch M (2007) IRF-1 gene variations influence IgE regulation and atopy. American Journal of Respiratory Critical Care Medicine in press Scheetz TE, Kim KY, Swiderski RE, Philp AR, Braun TA, Knudtson KL, Dorrance AM, Dibona GF, Huang J, Casavant TL, Sheffield VC and Stone EM (2006) Regulation of gene expression in the mammalian eye and its relevance to eye disease. Proceedings of the National Academy of Sciences USA 103 14429-14434 Scheibner KA, Lutz MA, Boodoo S, Fenton MJ, Powell JD and Horton MR (2006) Hyaluronan fragments Act as an endogenous danger signal by engaging TLR2. Journal of Immunology 177 1272-1281 Scheid MP and
Woodgett JR (2000) Protein kinases: six degrees of separation? Current Biology
10 R191-R194 Scheidereit C
(1998) Docking IkB kinases. Nature 395 225-226 Scheidereit C (2003) The pathogenetic significance of deregulated signal transduction pathways in Hodgkin's disease: the NF-kB-AP-1 network. Verh Dtsch Ges Pathol 87 79-89 Scheidereit
C (2006) IkB kinase complexes: gateways to NF-kB activation and transcription. Scheinman RI,
Beg AA and Baldwin Jr AS (1993) NF-kB p100 (lyt-10) is a component of H2TF1
and can function as an IkB-like molecule. Molecular and Cellular Biology 13
6089-6101 Scheinman RI,
Cogswell PC, Lofquist AK and Baldwin Jr AS (1995) Role of transcriptional
activation of IkBa in mediation of immunosuppression by glucocoritcoids.
Science 270 283-286 Scheinman RI,
Gualberto A, Jewell CM, Cidlowski J and Baldwin Jr AS (1995) Characterization
of mechanisms involved in transrepression of NF-kB by activated glucocorticoid
receptors. Molecular and Cellular Biology 15 943-953 Shelest E, Kel A, Goessling E and Wingender E (2002) Prediction of potential C/EBP/NF-kappaB composite elements using matrix-based search methods. In Silico Biology 3 71-79 Schell MT, Spitzer AL, Johnson JA, Lee D and Harris HW (2005) Heat shock inhibits NF-kB activation in a dose- and time-dependent manner. Journal of Surgical Research 129 90-93 Scheller C,
Sopper S, Chen P, Flory E, Koutsilieri E, Racek T, Ludwig S, ter Meulen V and
Jassoy C (2002) Caspase inhibition activates HIV in latently infected cells:
Role of TNF-R1 and CD95. Journal of Biological Chemistry 277 15459-15464 Scheller C,
Sopper S, Ehrhardt C, Flory E, Chen P, Koutsilieri E, Ludwig S, Meulen Vt V
and Jassoy C (2002 Caspase inhibitors induce a switch from apoptotic to
proinflammatory signaling in CD95-stimulated T lymphocytes. European Journal
of Immunology 32 2471-2480 Scheller C, Ullrich A, McPherson K, Hefele B, Knoferle J, Lamla S, Olbrich AR, Stocker H, Arasteh K, Ter Meulen V, Rethwilm A, Koutsilieri E and Dittmer U (2004) CpG-oligodeoxynucleotides activate HIV replication in latently infected human T cells. Journal of Biological Chemistry 279 21897-21902 Schena FP, Cerullo G, Torres DD, Scolari F, Foramitti M, Amoroso A, PIrulli D, Floege J, Mertens PR, Zerres K, Alexopoulos E, Kirmizis D, Zelante L and Bisceglia L (2006) Role of interferon-gamma gene polymorphisms in susceptibility to IgA nephropathy: a family-based association study. European Journal of Human Genetics 14 488-496 Schenk H,
Klein M, Erdbrugger W, Droge W and Schulze-Osthoff K (1994) Distinct effects
of thioredoxin and antioxidants on the activation of transcription factors
NF-kB and AP-1. Proceedings of the National Academy of Sciences USA 91
1672-1676 Schenk S and Horowitz JF (2007) Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance. Journal of Clinical Investigation in press Schenning M, Goedhart J, Gadella Jr TS, Wirtz KW and Snoek Gt (2008) The anti-apoptotic activity associated with phosphatidylinositol transfer protein alpha activates the MAPK and Akt/PKB pathway. Biochemica et Biophysica Acta in press Schepers H, Eggen BJ, Schuringa JJ and Vellenga E (2006) Constitutive activation of NF-kB is not sufficient to disturb normal steady-state hematopoiesis. Haematologica 91 1710-1711 Schepers H, Geugien M, Eggen BJ and Vellenga D (2003) Constitutive cytoplasmic localization of p21(Waf1/Cip1) affects the apoptotic process in monocytic leukaemia. Leukemia 17 2113-2121 Schepetkin IA, Xie G, Kirpotina LN, Klein RA, Jutila MA and Quinn MT (2008) Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha. International Immunophamracology in press Scherer DC,
Brockman JA, Bendall HH, Zhang GM, Ballard DW and Oltz EM(1996) Corepression
of RelA and c-Rel inhibits immunoglobulin k gene transcription and
rearrangement in precursor B lymphocytes. Immunity 5 563-574 Scherer DC,
Brockman JA, Chen Z, Maniatis T and Ballard DW (1995) Signal-induced
degradation of IkBa requires site-specific ubiquitination. Proceedings of the
National Academy of Sciences USA 92 11259-11263 Schesser K,
Spiik AK, Dukuzumuremyi JM, Neurath MF, Pettersson S and Wolf-Watz H (1998)
The yopJ locus is required for Yersinia-mediated inhibition of NF-kB
activation and cytokine expression: YOPJ contains a eukaryotic SH2-like domain
that is essential for its repressive activity. Molecular Microbiology 28
1067-1079 Schett G, Hayer S, Zwerina J, Redlich K and Smolen JS (2005) Mechanisms of disease: the link between RANKL and arthritic bone disease. Nature Clinical Practice: Rheumatology 1 47-54 Schett G, Steiner CW, Xu Q, Smolen JS and Steiner G (2003) TNFalpha mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress response. Cell Death & Differentiation 10 1126-1136 Schiekofer S, Andrassy M, Chen J, Rudofsky G, Schneider J, Wendt T, Stefan N, Humpert P, Fritsche A, Stumvoll M, Schleicher E, Haring HU, Nawroth PP and Bierhaus A (2003) Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kB in PBMCs. Diabetes 52 621-633 Schiekofer S, Franke S, Andrassy M, Chen J, Rudofsky G, Schneider JG, von Eynatten M, Wendt T, Morcos M, Kientsch-Engel R, Stein G, Schleicher E, Nawroth PP and Bierhaus A (2006) Postprandial mononuclear NF-kB activation is independent of the AGE-content of a single meal. Experimental & Clinical Endocrinology & Diabetes 114 160-167 Schiekofer S, Galasso G, Andrassy M, Aprahaminan T, Schneider J and Rocnik E (2006) Glucose control with insulin results in reduction of NF-kB-binding activity in mononuclear blood cells of patients with recently manifested type 1 diabetes. Diabetes Obesisty and Metabolism 8 473-482 Schiekofer S,
Rudofsky G, Andrassy M, Schneider J, Chen J, Isermann B, Kanitz M, Elsenhans
S, Heinle H, Balletshofer B, Haring HU, Schleicher E, Nawroth PP and Bierhaus
A (2003) Glimepiride reduces mononuclear activation of the redox-sensitive
transcription factor nuclear factor-kB. Schieven GL,
Kirihara JM, Myers DE, Ledbetter JA and Uckun FM (1993) Reactive oxygen
intermediates activate NF-kB in a tyrosine kinase- dependent mechanism and in
combination with vanadate activate the p56 lck and p59 fyn tyrosine kinases in
human lymphocytes. Blood 82 1212-1220 Schiffer M,
Schiffer LE, Gupta A, Shaw AS, Roberts IS, Mundel P and Bottinger EP (2002)
Inhibitory Smads and TGF-beta signaling in glomerular cells. Journal of the American Society
of Nephrology
13 2657-2666 Schiller M, Metze D, Luger TA, Grabbe S and Gunzer M (2006) Immune response modifiers - mode of action. Experimental Dermatology 15 331-341 Schilling D,
Beissert T, Fenton MJ and Nixdorff K (2001) Negative regulation of IL-1beta
production at the level of transcription in macrophages stimulated with LPS.
Cytokine 16 51-61 Schilling JD, Martin SM, Hunstad DA, Patel KP, Mulvey MA, Justice SS, Lorenz RG and Hultgren SJ (2003) CD14- and Toll-like receptor-dependent activation of bladder epithelial Cells by lipopolysaccharide and type 1 piliated Escherichia coli. Infection & Immunity 71 1470-1480 Schindler H,
Lutz MB, Rollinghoff M and Bogdan C (2001) The production of IFN-gamma by
IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by
IL-4. Journal of Immunology 166 3075-3082 Schindler U
and Baichwal VR (1994) Three NF-kB binding sites in the human E-selectin gene
required for maximal tumor necrosis factor alpha-induced expression. Molecular
and Cellular Biology 14 5820-5831 Schins RP,
McAlinden A, MacNee W, Jimenez LA, Ross JA, Guy K, Faux SP and Donaldson K
(2000) Persistent depletion of IkBa and interleukin-8 expression in human
pulmonary epithelial cells exposed to quartz particles. Toxicology and Applied Pharmacology
167 107-117 Schjerven H,
Brandtzaeg P and Johansen FE (2001) A novel NF-kB/Rel site in intron 1
cooperates with proximal promoter elements to mediate TNF-alpha-induced
transcription of the human polymeric Ig receptor. Journal of Immunology 167
6412-6420 Schjerven H, Tran TN, Brandtzaeg P and Johansen FE (2004) De novo synthesized RelB mediates TNF-induced up-regulation of the human polymeric Ig receptor. Journal of Immunology 173 1849-1857 Schlaak JF, Barreiros AP, Pettersson S, Schirmacher P, Meyer Zum Buschenfelde KH and Neurath MF (2001) Antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kB abrogate fulminant septic shock induced by S. typhimurium in mice. Scandinavian Journal of Immunology 54 396-403 Sclabas GM,
Fujioka S, Schmidt C, Evans DB and Chiao PJ (2003) NF-kB in pancreatic cancer. Schlee M, Harder J, Koten B, Stange EF, Wehkamp J and Fellermann K (2008) Probiotic lactobacilli and VSL#3 induce enterocyte beta-defensin 2. Clinical and Experimental Immunology in press Schlee M, Holzel M, Bernard S, Mailhammer R, Schuhmacher M, Reschke J, Eick D, Marinkovic D, WIrth T, Rosenwald A, Staudt LM, Eilers M, Baran-Marszak F, Fagard R, Feuillard J, Laux G and Bornkamm GW (2007) c-MYC activation impairs the NF-kB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma. International Journal of Cancer 120 1387-1395 Schlee M, Schuhmacher M, Holzel M, Laux G and Bornkamm GW (2007) c-MYC impairs immunogenicity of human B cells. Advances in Cancer Research 97 167-1688 Schlee M, Wehkamp J, Altenhofefer A, Oelschlaeger TA, Stang EF and Fellermann K (2007) The induction of human beta-defensin-2 by the probiotic Escherichia coli Nissle 1917 is mediated through flagellin. Infection and Immunity 75 2399-2407 Schleicher E and Friess U (2007) Oxidative stress, AGE, and atherosclerosis. Kidney International Supplement 106 S17-S26 Schleicher
ED, Bierhaus A, Haring HU, Nawroth PP and Lehmann R (2001) Chemistry and
pathobiology of advanced glycation end products. Contributions to Nephrology 131 1-9 Schlemper V, Medeiros R, Ferreira J, Campos MM and Calixto JB (2005) Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro. British Journal of Pharmacology 145 740-750 Schleser S, Ringseis R and Eder K (2006) Conjugated linoleic acids have no effect on TNFa-induced adhesion molecule expression, U937 monocyte adhesion, and chemokine release in human aortic endothelial cells. Atherosclerosis 196 337-344 Schlette E, Rassidakis GZ, Canoz O and Medeiros LJ (2005) Expression of bcl-3 in chronic lymphocytic leukemia correlates with trisomy 12 and abnormalities of chromosome 19. American Journal of Clinical Pathology 123 465-471 Schlezinger
JJ, Blickarz CE, Mann KK, Doerre S and Stegeman JJ (2000) Identification of
NF-kappaB in the marine fish Stenotomus chrysops and examination of its
activation by aryl hydrocarbon receptor agonists. Chemico-Biological Interactions 126
137-157 Schlezinger JJ, Howard GJ, Hurst CH, Emberley JK, Waxman DJ, Webster T and Sherr DH (2004) Environmental and endogenous peroxisome proliferator-activated receptor {gamma} agonists induce bone marrow B cell growth arrest and apoptosis: interactions between mono(2-ethylhexyl)phthalate, 9-cis-retinoic acid, and 15-deoxy-{Delta}12,14-prostaglandin J2. Journal of Immunology 173 3165-3177 Schlezinger JJ, Jensen BA, Mann KK, Ryu HY and Sherr DH (2002) Peroxisome proliferator-activated receptor gamma-mediated NF-kB activation and apoptosis in pre-B cells. Journal of Immunology 169 6831-6841 Schlondorff D
and Segerer S (1999) Pathogenesis of glomerulonephritis, a perspective from
the last 30 years. Journal of Nephrology 12 Suppl 2 S131-S141 Schlottmann S, Buback F, Stahl B, Meierhenrich R, Walter P, Georgieff M and Senftleben U (2008) Prolonged classical NF-kB activation prevents autophagy upon E. coli stimulation in vitro: a potential resolving mechanism of inflammation. Mediators of Inflammation 2008 725854 Schmeck B, Beermann W, N'guessan PD, Nocke AC, Opitz B, Eitel J, Dinh QT, Witzenrath M, Krull M, Suttorp N and Hippenstiel S (2008) Simvastatin reduces Chlamydophila pneumoniae-mediated histone modifications and gene expression in cultured human endothelial cells. Circulation Research 102 888-895 Schmeck B, Beermann W, van Laak V, Opitz B, Hocke AC, Meixenberger K, Eitel J, Chakraborty T, Schmidt G, Barth H, Suttorp N and Hippenstiel S (2006) Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells. Biochemical Pharmacology 72 1367-1374 Schmeck B, Brunsch M, Seybold J, Krull M, Eichel-Streiber C, Suttorp N and Hippenstiel S (2003) Rho protein inhibition blocks cyclooxygenase-2 expression by proinflammatory mediators in endothelial cells. Inflammation 27 89-95 Schmeck B, Huber S, Moog K, Zahlten J, Hocke AC, Opitz B, Mammerschmidt S, Mitchell TJ, Kracht M, Rosseau S, Suttorp N and Hippenstiel S (2006) Pneumococci induced TLR- and Rac1-dependent NF-kB-recruitment to the IL-8 promoter in lung epithelial cells. American Journal of Physiology: Lung Cell and Molecular Physiology 290 L730-L737 Schmeck B, Lorenz J, N'guessan PD, Opitz B, van Laak V, Zahlten J, Slevogt H, Witzenrath M, Flieger A, Suttorp N and Hippenstiel S (2008) Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression. Journal of Immunology 181 940-947 Schmeck B, N'Guessan PD, Ollomang M, Lorenz J, Zahlten J, Opitz B, Flieger A, Suttorp N and Hippenstiel S (2007) L. pneumophila induced NF-kB- and MAPK-dependent cytokine release by lung epithelial cells. European Respiratory Journal29 25-33 Schmeck B, Zahlten J, Moog K, van Laak V, Huber S, Hocke AC, Opitz B, Hoffmann E, Kracht M, Zerrahn J, Hammerschmidt S, Rosseau S, Suttorp N and Hippenstiel S (2004) Streptococcus pneumoniae induced p38 MAPK dependent phosphorylation of RelA at the interleukin-8 promotor.Journal of Biological Chemistry 279 53241-53247 Schmeisser A, Soehnlein O, Illmer T, Lorenz HM, Eskafi S, Roerick O, Gabler C, Strasser R, Daniel WG and Garlichs CD (2004) ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kB activity and AT1 receptor expression. Biochemical and Biophysical Research Communications 325 532-540 Schmelz K, Wieder T, Tamm I, Muller A, Essmann F, Geilen CC, Schulze-Osthoff K, Dorken B and Daniel PT (2004) Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kB. Oncogene 23 6743-6759 Schmid H, Boucherot A, Yasuda Y, Henger A, Brunner B, Eichinger F, Nitsche A, Kiss E, Bleich M Grone HJ, Nelson PJ, Schlondorff D, Cohen CD and Kretzler M (2006) Modular activation of nuclear factor-kB transcriptional programs in human diabetic nephropathy. Diabetes 55 2993-3003 Schmid JA and Birbach A (2008) IkB kinase b (IKKbeta/IKK2/IKBKB)-A key molecule in signaling to the transcription factor NF-kB. Cytokine and Growth Factor Reviews in press Schmid JM, Junge SA, Hossle JP, Schneider EM, Roosnek E, Seger RA and Gungor T (2006) Transient hemophagocytosis with deficient cellular cytotoxicity, monoclonal immunoglobulin M gammopathy, increased T-cell numbers, and hypomorphic NEMO mutation. Pediatrics 117 e1049-e1056 Schmid MC, Schulein R, Dehio M, Denecker G, Carena I and Dehio C (2004) The VirB type IV secretion system of Bartonella henselae mediates invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. Molecular Microbiology 52 81-92 Schmid RM and
Adler G (2000) NF-kB/rel/IkB: implications in gastrointestinal diseases. Gastroenterology 118 1208-1228 Schmid RM,
Adler G and Liptay S (1998) Activation of NFkB in inflammatory bowel disease. Gut 43 587-588 Schmid RM,
Perkins ND, Duckett CS, Andrews PC and Nabel GJ (1991) Cloning of an NF-kB
subunit which stimulates HIV transcription in synergy with p65. Nature 352
733-736 Schmid Y, Grassl GA, Buhler OT, Skurnik M, Autenrieth IB and Bohn E (2004) Yersinia enterocolitica adhesin A induces production of interleukin-8 in epithelial cells. Infection and Immunity 72 6780-6789 Schmidmaier R and Baumann P (2008) Anti-adhesion evolves to a promising therpaeutic concept in oncology. Current Medical Chemistry 15 978-990 Schmidt A, Geigenmuller S, Volker W and Buddecke E (2006) The antiatherogenic and antiinflammatory effect of HDL-associated lysosphingolipids operates via Akt NF-kB signalling pathways in human vascular endothelial cells. Basic Research in Cardiology 101 109-116 Schmidt A,
Hennighausen L and Siebenlist U (1990) Inducible nuclear factor binding to the
kB elements of the human immunodeficiency virus enhancer in T cells can be
blocked by cyclosporin A in a signal-dependent manner. Journal of Virology 64
4037-4041 Schmidt A, Vogel R, Rutledge SJ, Opas EE, Rodan GA and Friedman E (2005) Cross-talk between an activator of nuclear receptors-mediated transcription and the D(1) dopamine receptor signaling pathway. Pharmacol Biochem Behav 80 379-385 Schmidt C, Hocherl K, Kurt B and Bucher M (2008) Role of NF-kB-dependent induction of cytokines in the regulation of vasopressin V1A-receptors during cecal ligation and puncture-induced circulatory failure. Critical Care Medicine in press Schmidt C, Peng B, Li Z, Sclabas GM, Fujioka S, Niu J, Schmidt-Supprian M, Evans DB, Abbruzzese JL and Chiao PJ (2003) Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. Molecular Cell 12 1287-1300 Schmidt CS, Liu J, Zhang T, Song HY, Sandusky G, Mintze K, Benschop RJ and Glasebrook A, Yang DD, Na S (2003) Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6. Journal of Experimental Medicine 197 51-62 Schmidt D, Textor B, Pein OT, Licht AH, Andrecht S, Sator-Schmitt M, Fusenig NE, Angel P and Schorpp-Kistner M (2007) Critical role for NF-kB-induced JunB in VEGF regulation and tumor angiogenesis. EMBO Journal in press Schmidt
KN,
Amstad P, Cerutti P and Baeuerle PA (1995) The roles of hydrogen peroxide and
superoxide as messengers in the activation of transcription factor NF-kB.
Chemistry & Biology 2 13-22 Schmidt KN, Leung B, Kwong M, Zarember KA, Satyal S, Navas TA, Wang F and Godowski PJ (2004) APC-Independent Activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA. Journal of Immunology 172 138-143 Schmidt KN,
Podda M, Packer L and Baeuerle PA (1996) Anti-psoriatic drug anthralin
activates transcription factor NF-kB in murine keratinocytes. Journal of
Immunology 156 4514-4519 Schmidt KN,
Traenckner EBM, Frank RW, Saviano G and Baeuerle PA (1995) Induction of
oxidative stress by okadaic acid is required for activation of transcription
factor NF-kB. Journal of Biological Chemistry 270 27165-27142 Schmidt NW, Thieu VT, Mann BA, Ahyi AN and Kaplan MH (2006) Bruton's tyrosine kinase is required for TLR-induced IL-10 production. Journal of Immunology 177 7203-7210 Schmidt R, Bultmann A, Fischel S, Gillitzer A, Cullen P, Walch A, Jost P, Ungerer M, Tolley ND, Lindemann S, Gawaz M, Schomig A and May AE (2007) Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kB dependent inflammation in monocytes. Circulation Research in press Schmidt S, Westhoff TH, Krauser P, Ignatium R, Jankowski J, Jankowski V, Zidek W and Giet MV (2008) The uraemic toxin phenylacetic acid impairs macrophage function. Nephrology, Dialysis and Transplantation in press Schmidt
TJ,
Lyss G, Pahl HL and Merfort I (1999) Helenanolide type sesquiterpene lactones.
Part 5: the role of glutathione addition under physiological conditions.
Bioorg Med Chem 7 2849-2855 Schmidt WE,
Arlt A, Trauzold A and Schafer H (1999) p22/PRG1: a novel early response gene
in pancreatic cancer cells regulated by p53 and NFkB. Annals of the New York
Academy of Sciences 880 147-156 Schmidt-Supprian
M, Bloch W, Courtois G, Addicks K, Israel A, Rajewsky K and Pasparakis M
(2000) NEMO/IKKg-deficient mice model incontinentia pigmenti. Molecular Cell 5
981-992 Schmidt-Supprian M, Courtois G, Tian J, Coyle AJ, Israel A, Rajewsky K and Pasparakis M (2003) Mature T cells depend on signaling through the IKK complex. Immunity 19 377-389 Schmidt-Supprian M, Tian J, Grant EP, Pasparakis M, Maehr R, Ovaa H, Ploegh HL, Coyle AJ and Rajewsky K (2004) Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kB activation. Proceedings of the National Academy of Sciences USA 101 4566-4571 Schmidt-Supprian M, Tian J, Ji H, Terhorst C, Bhan AK, Grant EP, Pasparakis M, Casola S, Coyle AJ and Rajewsky K (2004) IkB kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion. Journal of Immunology 173 1612-1619 Schmidt-Ullrich
R, Aebischer T, Hulsken J, Birchmeier W, Klemm U and Scheidereit C (2001)
Requirement of NF-kB/Rel for the development of hair follicles and other
epidermal appendices. Development 128 3843-3853 Schmid-Ullrich
R, Mémet S, Lilienbaum A, Feuillard J, Raphaël M and Israël A (1996) NF-kB
activity in transgenic mice: developmental regulation and tissue specificity.
Development 122 2117-2128 Schmidt-Ullrich R, Tobin DJ, Lenhard D, Schneider P, Paus R and Scheidereit C (2006) NF-kB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development 133 1045-1057 Schmidtko A, Burian M, Altis K, Hardt K, Angioni C, Schmidt R, Podda M and Geisslinger G (2006) Pharmacological and histopathological characterization of a hyperalgesia model induced by freeze lesion. Pain in press Schmitz F, Heit A, Guggemoos S, Krug A, Mages J, Schiemann M, Adler H, Drexler I, Haas T, Lang R and Wagner H (2007) Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells. European Journal of Immunology 37 315-327 Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan TK, Zurawaki G, Moshrefi M, Qin J, Li X, Gorman DM, Basan JF and Kastelein RA (2005) IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23 479-490 Schmitz ML
and Baeuerle PA (1991) The p65 subunit is responsible for the strong
transcription activating potential of NF-kB by p65. EMBO Journal 10 3805-3817 Schmitz ML
and Baeuerle PA (1994) A vector, pHisGal, allowing bacterial production of
proteins fused to a hexahistidine-tagged Gal4 DNA-binding domain.
BioTechniques 17 714-718 Schmitz ML
and Baeuerle PA (1995) Multi-step activation of NF-kB/Rel transcription
factors. Immunobiology 193 116-127 Schmitz ML, Bacher S and Dienz O (2003) NF-kB activation pathways induced by T cell costimulation. FASEB Journal 17 2187-2193 Schmitz ML,
Bacher S and Kracht M (2001) IkB-independent control of NF-kB activity by
modulatory phosphorylations. Trends Biochemical Sciences 26 186-190 Schmitz ML,
dos Santos Silva MA and Baeuerle PA (1995) Transactivation domain 2 (TA2) of
p65 NF-kB. Similarity to TA1 and phorbol-ester-stimulated activity and
phosphorylation in intact cells. Journal of Biological Chemistry 270
15576-15584 Schmitz ML,
Henkel T and Baeuerle PA (1991) Proteins controlling the nuclear uptake of
NF-kB, Rel and dorsal. Trends in Cell Biology 1 130-137 Schmitz ML,
Indorf A, Limbourg FP, Städler H, Traenckner EB-M and Baeuerle PA (1996) The
dual effect of adenovirus type 5 E1A 13S protein on activation of
transcription factor NF-kB is antagonized by E1B 19 kDa. Molecular and
Cellular Biology 15 4052-4063 Schmitz ML and Krappmann D (2006) Controlling NF-kB activation in T cells by costimulatory receptors. Cell Death and Differentiation13 834-842 Schmitz ML, Mattioli I, Buss H and Kracht M (2004) NF-kB: a multifaceted transcription factor regulated at several levels. Chembiochem 5 1348-1358 Schmitz ML,
Stelzer G, Altmann H, Meisterernst M and Baeuerle PA (1995) Interaction of the
COOH-terminal transactivation domain of p65 NF-kB with TATA-binding protein,
transcription factor IIB, and coactivators. Journal of Biological Chemistry
270 7219-7226 Schmitz-Peiffer C and Whitehead JP (2003) IRS-1 regulation in health and disease. IUBMB Life 55 367-374 Schneeberger S, Hautz T, Wahl SM, Brandacher G, Sucher R, Steinmassl O, Steinmassl P, Wright CD, Obrist P, Werner ER, Mark W, Troppmair J, Margreiter R and Amberger A (2008) The effect of secretory leukocyte protease inhibitor (SLPI) on ischemia/reperfusion injury in cardiac transplantation. American Journal of Transplantation in press Schneeman TA, Bruno ME, Schjerven H, Johansen FE, Chady L, Kaetzel CS (2005) Regulation of the polymeric Ig receptor by signaling through TLRs 3 and 4: linking innate and adaptive immune responses. Journal of Immunology 175 376-384 Schneider A,
Martin-Villalba A, Weih F, Vogel J, Wirth T and Schwaninger M (1999) NF-kB is
activated and promotes cell death in focal cerebral ischemia. Nature Medicine
5 554-559 Schneider C, Strayhorn WD, Brantley DM, Nanney LB, Yull FE and Brash AR (2004) Upregulation of 8-lipoxygenase in the dermatitis of IkB-a-deficient mice. Journal of Investigative Dermatology 122 691-698 Schneider DS,
Hudson KL, Lin T-Y and Anderson KV (1991) Dominant and recessive mutations
define functional domains in Toll, a transmembrane protein required for
dorsal-ventral polarity in the Drosophila embryo. Genes & Development 5
797-807 Schneider F, Neugebauer J, Griese J, Liefold N, Kutz H, Briseno C and Kieser A (2008) The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity. PLoS Biology 6 e8 Schneider G, Saur D, Siveke JT, Fritsch R, Greten FR and Schmid RM (2006) IKKa controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression. EMBO Journal 25 3801-3812
Schneider G, Weber A, Zechner Y, Oswald F, Friess HM, Schmid RM
and Liptay S (2005) GADD45alpha is highly expressed in pancreatic ductal
adenocarcinoma cells and required for tumor cell viability. Schneider K, Loewendorf A, De Trez C, Fulton J, Rhode A, Shumway H, Ha S, Pattersn G, Pfeffer K, Nedospasov SA, Ware CF and Benedict CA (2008) Lymphotoxin-mediated crosstalk between B cells and splenic stroma promotes the initial type I interferon response to cytomegalovirus. Cell Host Microbe 3 67-76 Schneider P, Olson D, Tardivel A, Browning B, Lugovskoy A, Gong D, Dobles M, Hertig S, Hofmann K, Van Vlijmen H, Hsu YM, Burkly LC, Tschopp J and Zheng TS (2002) Identification of a new murine TNF receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Journal of Biological Chemistry 278 5444-5454
Schneider P,
Schwenzer R, Haas E, Muhlenbeck F, Schubert G, Scheurich P, Tschopp J and
Wajant H (1999) TWEAK can induce cell death via endogenous TNF and TNF
receptor 1. European Journal of Immunology 29 1785-1792 Schneider R, Braunstein S, Formenti S and Liebes L (2003) Stage/grade-specific chemo-radiation sensitization of intraductal breast carcinoma cell lines by inhibition of NF-kB. Int J Radiat Oncol Biol Phys 57 S296-S297 Schneider-Brachert W, Tchikov V, Merkel O, Jakob M, Hallas C, Kruse ML, Groitl P, Lehn A, Hildt E, Held-Feindt J, Dobner T, Kabelitz D, Kronke M and Schutze S (2006) Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism. Journal of Clinical Investigation 116 2901-2913 Schnekenburger M, Morceau F, Duvoix A, Delhalle S, Trentesaux C, Dicato M and Diederich M (20040 Increased glutathione S-transferase P1-1 expression by mRNA stabilization in hemin-induced differentiation of K562 cells. Biochemical Pharmacology 68 1269-1277 Schnitzler AC, Burke JM and Wetzler LM (2007) Induction of cell signaling events by cholera toxin B-subunit in antigen presenting cells. Infection and Immunity in press Schnur RE (2004) Genodermatoses 2003-2004. Current Opinion in Pediatrics 16 678-688 Schnyder B, Schnyder-Candrian S, Pansky A, Schmitz ML, Heim M, Ryffel B and Moser R (2005) IL-17 reduces TNF-induced Rantes and VCAM-1 expression. Cytokine 31 191-202 Schoemaker MH, Conde De La Rosa L, Buist-Homan M, Vrenken TE, Havinga R, Poelstra K, Haisma HJ, Jansen PL and Moshage H (2004) Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways. Hepatology 39 1563-1573 Schoemaker MH, Gommans WM, de la Rosa LC, Homan M, Klok P, Trautwein C, van Goor H, Poelstra K, Haisma HJ, Jansen PL and Moshage H (2003) Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kB activation. Journal of Hepatology 39 153-161
Schoemaker MH,
Ros JE, Homan M, Trautwein C, Liston P, Poelstra K, van Goor H, Jansen PL and
Moshage H (2002) Cytokine regulation of pro- and anti-apoptotic genes in rat
hepatocytes: NF-kB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents
apoptosis. Journal of Hepatology 36 742-750 Schoemaker MH,
Ros JE, Homan M, Trautwein C, Liston P, Poelstra K, van Goor H, Jansen PL and
Moshage H (2002) Cytokine regulation of pro- and anti-apoptotic genes in rat
hepatocytes: NF-kB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents
apoptosis. Journal of Hepatology 36 742-750 Schoenfelder S and Fraser P (2008) Interchromosomal huddle kickstarts antiviral defense. Cell 134 14-16 Scholz H, Yndestad A, Damas JK, Waehre T, Tonstad S, Aukrust P and Halvorsen B (2003) 8-Isoprostane increases expression of interleukin-8 in human macrophages through activation of mitogen-activated protein kinases. Cardiovascular Research 59 945-954 Scholz M, Doerr HW and Cinatl J (2003) Human cytomegalovirus retinitis: pathogenicity, immune evasion and persistence. Trends in Microbiology 11 171-178 Scholz M, Nowak P, Schuller A, Margraf S, Blaheta R, Cinatl J, Windolf J and Moritz A (2004) Cardiac surgery with extracorporeal circulation: neutrophil transendothelial migration is mediated by beta1 integrin (CD29) in the presence of TNF-alpha. Journal of Investigative Surgery 17 239-247 Scholz M, Vogel JU, Hover G, Kotchetkov R, Cinatl J, Doerr HW and Cinatl J (2004) Thrombin stimulates IL-6 and IL-8 expression in cytomegalovirus-infected human retinal pigment epithelial cells. International Journal of Molecular Medicine 13 327-331 Scholzke MN, Potrovita I, Subramaniam S, Prinz S and Schwaninger M (2003) Glutamate activates NF-kB through calpain in neurons. European Journal of Neuroscience 18 3305-3310 Scholzke MN and Schwaninger M (2007) Transcriptional regulation of neurogenesis: potential mechanisms in cerebral ischemia. Journal of Molecular Medicine in press Schon M and Schon MP (2007) The antitumoral mode of action of imiquimod and other imidazoquinolines. Current Medicinal Chemistry 14 681-687 Schon MP and Schon M (2006) The small-molecule immune response modifier imiquimod--its mode of action and clinical use in the treatment of skin cancer. Expert Opinion in Thereapuetic Targets 10 69-76 Schomer-Miller B, Higashimoto T, Lee Y-K and Zandi E (2006) Regulation of IkB kinase (IKK) complex by IKKgamma-dependent phosphorylation of the T-loop and C terminus of IKKb. Journal of Biological Chemistry 281 15268-15276 Schon M, Wienrich BG, Kneitz S, Sennefelder H, AMschler K, Vohringer V, Weber O, Stiewe T, Ziegelbauer K and Schon MP (2008) KINK-1, a novel small-molecule inhibitor of IKKb, and the susceptibility of melanoma cells to antitumoral treatment. Journal of the National Cancer Institute in press Schon MP and Schon M (2008) TLR7 and TLR8 as targets in cancer therapy. Oncogene 27 190-199 Schon MP and Schon M (2007) Imiquimod: mode of action. British Journal of Dermatology 157 S8-S13 Schon MP, Schon M and Klotz KN (2006) The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. Journal of Investigative Dermatology 126 1338-1347 Schoner W and Scheiner-Bobis G (2007) Endogenous and exogenous cardiac glycosides: Their roles in hypertension, salt metabolism, and cell growth. American Journal of Physiology: Cell Physiology in press Schoner W and Scheiner-Bobis G (2007) Endogenous and exogenous cardiac glycosides and their mechanisms of action. American Journal of Cardiovascular Drugs 7 173-189 Schooley K,
Zhu P, Dower SK and Qwarnstrom EE (2003) Regulation of nuclear translocation
of NF-kB RelA: Evidence for complex dynamics at the single cell level. Biochemical
Journal 369 331-339 Schoonbroodt
S, Ferreira V, Best-Belpomme M, Boelaert JR, Legrand-Poels S, Korner M and
Piette J (2000) Crucial role of the amino-terminal tyrosine residue 42 and the
carboxyl-terminal PEST domain of IkB alpha in NF-kB activation by an oxidative
stress. Journal of Immunology 164 4292-4300 Schopf L, Savinainen A, Anderson K, Kujawa J, Dupont M, Silva M, Siebert E, Chandra S, Morgan J, Gangurde P, Wen D, Lane J, Xu Y, Hepperle M, Harriman G, Ocain T and Jaffee B (2006) IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis. Arthritis and Rheumatism 54 3163-3173 Schoppet M, Henser S, Ruppert V, Stubig T, Al-Fakhri N, Maisch B and Hofbauer LC (2006) Osteoprotegerin expression in dendritic cells increases with maturation and is NF-kB-dependent. Journal of Cellular Biochemistry in press Schorr K,
Garcia-Pineres AJ, Siedle B, Merfort I and Da Costa FB (2002) Guaianolides
from Viguiera gardneri inhibit the transcription factor NF-kB. Phytochemistry
60 733-740 Schott-Ohly P, Lgssiar A, Partke HJ, Hassan M, Friesen N and Gleichmann H (2004) Prevention of Spontaneous and experimentally induced diabetes in mice with zinc sulfate-Enriched drinking water is associated with activation and reduction of NF-kB and AP-1 in islets, respectively. Exp Biol Med 229 1177-1185 Schotte P,
Van Loo G, Carpentier I, Vandenabeele P and Beyaert R (2001) Lithium
sensitizes tumor cells in an NF-kB-independent way to caspase activation and
apoptosis induced by tumor necrosis factor (TNF). Evidence for a role of the
TNF receptor-associated death domain protein. Journal of Biological Chemistry
276 25939-25945 Schottelius
AJ and Baldwin Jr AS (1999) A role for transcription factor NF-kB in
intestinal inflammation. International Journal of Colorectal Disease 14 18-28 Schottelius AJ and Dinter H (2006) Cytokines, NF-kB, microenvironment, intestinal inflammation and cancer. Cancer Treatment and Research 130 67-87 Schottelius
AJ, Mayo MW, Sartor RB and Baldwin AS, Jr. (1999) Interleukin-10 signaling
blocks inhibitor of kB kinase activity and nuclear factor kB DNA binding.
Journal of Biological Chemistry 274 31868-31874 Schouten GJ,
van der Eb AJ and Zantema A (1995) Downregulation of MHC class I expression
due to interference with p105-NFkB1 processing by Ad12E1A. EMBO Journal 14
1498-1507 Schouten GJ,
Vertegall ACO, Whiteside ST, Israël A, Toebes M, Dorsman JC, van der Eb AJ
and Zantema A (1997) IkBa is a target for the mitogen-activated 90 kDa
ribosomal S6 kinase. EMBO Journal 16 3133-3144 Schram BR and Rothstein TL (2003) NF-kB is required for surface Ig-induced fas resistance in B cells. Journal of Immunology 170 3118-3124 Schreck R and
Baeuerle PA (1991) A role for oxygen radicals as second messengers. Trends in
Cell Biology 1 39-42 Schreck R and
Baeuerle PA (1994) Methods of assessing oxygen radicals as mediators in the
activation of the inducible transcription factor NF-kB. Methods in Enzymology
234 151-163 Schreck R,
Albermann K and Baeuerle PA (1992) Nuclear factor kB: an oxidative
stress-responsive transcription factor of eukaryotic cells. Free Radical
Research Communications 17 221-237 Schreck R,
Bevec D, Dukor P, Baeuerle PA, Chedid L and Bahr GM (1992) Selection of a
muramyl peptide based on its lack of activation of Nuclear Factor-kB as a
potential adjuvant for AIDS vaccines. Clinical and Experimental Immunology 90
188-193 Schreck R,
Grassmann R, Fleckenstein B and Baeuerle PA (1992) Antioxidants selectively
suppress activation of NF-kB by human T-cell leukemia virus type I Tax
protein. Journal of Virology 66 6288-6293 Schreck R,
Meier B, Männel DN, Dröge W and Baeuerle PA (1992) Dithiocarbamates as
potent inhibitors of nuclear factor kB activation in intact cells. Journal of
Experimental Medicine 175 1181-1194 Schreck R,
Rieber P and Baeuerle PA (1991) Reactive oxygen intermediates as apparently
widely used messengers in the activation of the NF-kB transcription factor and
HIV-1. EMBO Journal 10 2247-2258 Schreck R,
Zorbas H, Winnacker E-L and Baeuerle PA (1990) The NF-kB transcription factor
induces DNA bending which is modulated by its 65-kD subunit. Nucleic Acids
Research 18 6497-6502 Schreiber J, Efron PA,Park JE, Moldawer LL and Barbul A (2005) Adenoviral gene transfer of an NF-kB super-repressor increases collagen deposition in rodent cutaneous wound healing. Surgery 138 940-946 Schreiber J, Jenner RG, Murray HL, Gerber GK, Gifford DK and Young RA (2006) Coordinated binding of NF-kB family members in the response of human cells to lipopolysaccharide. Proceedings of the National Academy of Sciences USA in press Schreiber S
(1999) Activation of nuclear factor kB as a target for anti-inflammatory
therapy. Gut 44 309-310 Schreiner B, Baur DM, Fingerle AA, Zechner U, Greten FR, Adler G, Sipos B, Kloppel G, Hameister H and Schmid RM (2003) Pattern of secondary genomic changes in pancreatic tumors of Tgf alpha/Trp53+/- transgenic mice. Genes, Chromosomes & Cancer 38 240-248 Schreiner B, Voss J, Wischhusen J, Dombrowski Y, Steinle A, Lochmuller H, Dalakas M, Melms A and Wiendl H (2006) Expression of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release, and up-regulation of NKG2D-ligands. FASEB Journal 20 118-120 Schroder M and Bowie AG (2007) An arms race: innate antiviral responses and counteracting viral strategies. Biochemical Society Transactions 35 1512-1514 Schroder M and Kaufman RJ (2006) Divergent roles of IRE1a and PERK in the unfolded protein response. Current Molecular Medicine 6 5-36 Schroder NW,
Opitz B, Lamping N, Michelsen KS, Zahringer U, Gobel UB and Schumann RR (2000)
Involvement of lipopolysaccharide binding protein, CD14, and Toll-like
receptors in the initiation of innate immune responses by Treponema
glycolipids. Journal of Immunology 165 2683-2693 Schroeder RA,
Cai C and Kuo PC (1999) Endotoxin-mediated nitric oxide synthesis inhibits
IL-1beta gene transcription in ANA-1 murine macrophages. American Journal of
Physiology 277 C523-C530 Schroeter CH, Schaub B, Gold DR, Contreras PJ, Manrique O, Gillman MW, Weiss S, Palmer LJ, Perkins D and Finn PW (2004) Nuclear factor kB activation in human cord blood mononuclear cells. Pediatric Research 56 212-218 Schrum LW,
Black D, Iimuro Y, Rippe RA, Brenner DA and Behrns KE (2000) c-Jun does not
mediate hepatocyte apoptosis following NFkB inhibition and partial hepatectomy.
Journal of Surgical Research 88 142-149 Schubert A, Schulz H, Emons G and Grundker C (2008) Expression of osteoprotegerin and receptor activator of nuclear factor-kB ligand (RANKL) in HCC70 breast cancer cells and effects of treatment with gonadotropin-releasing hormone on RANKL expression. Gynecological Endocrinology 24 331-338 Schubert LA,
Cron RQ, Cleary AM, Brunner M, Song A, Lu LS, Jullien P, Krensky AM and Lewis
DB (2002) A T cell-specific enhancer of the human CD40 ligand gene.
Journal of Biological Chemistry 277 7386-7395 Schubert SY,
Neeman I and Resnick N (2002) A novel mechanism for the inhibition of NFkB
activation in vascular endothelial cells by natural antioxidants. FASEB
Journal 16 1931-1933 Schuchmann M
and Galle PR (2002) Dead or alive - NF-kB, the guardian which tips the
balance. Journal of Hepatology 36 827-828 Schugar RC, Robbins PD and Deasy BM (2007) Small molecules in stem cell self-renewal and differentiation. Gene Therapy in press Schupoli MT, Donadelli M, Cioffi F, Rossi M, Perbellini O, Malpeli G, Corbioli S, Cinante F, Krampera M, Palmieri M, Scarpa A, Ariola C, Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kB and JNK/AP-1 pathways. Haematologica in press Schuller M, Izakovicova Holla L, Buckova D, Znojil V, Stelcl M, Rybnicek O and Vacha J (2003) The role of the IKAP gene polymorphisms in atopic diseases in the middle European population. Journal of Human Genetics 48 300-304 Schuller-Levis GB and Park E (2003) Taurine: new implications for an old amino acid. FEMS Microbiol Letters 226 195-202 Schuller-Levis
GB and Park E (2004) Taurine and its chloramine: modulators of immunity. Schulte R,
Grassl GA, Preger S, Fessele S, Jacobi CA, Schaller M, Nelson PJ and
Autenrieth IB (2000) Yersinia enterocolitica invasin protein triggers IL-8
production in epithelial cells via activation of rel p65-p65 homodimers. FASEB Journal 14 1471-1484 Schultz C, Konig HG, Del Turco D, Politi C, Eckert GP, Ghebremedhin E, Prehn JH, Kogel D and Deller T (2006) Coincident enrichment of phosphorylated IkappaBalpha, activated IKK, and phosphorylated p65 in the axon initial segment of neurons. Molecular and Cellular Neuroscience in press Schultz DR and Harringto WJ Jr (2003) Apoptosis: Programmed cell death at a molecular level. Seminars in Arthritis and Rheumatitis 32 345-369 Schulze G
(2004) Sleep protects excitatory cortical circuits against oxidative damage. Schulze PC, De Keulenaer GW, Kassik KA, Takahashi T, Chen Z, Simon DI and Lee RT (2003) Biomechanically induced gene IEX-1 inhibits vascular smooth muscle cell proliferation and neointima formation. Circulation Research 93 1210-11217 Schulze-Luehrmann J and Ghosh S (2006) Antigen-receptor signaling to nuclear factor kB. Immunity 25 701-715 Schulze-Luehrmann
J, Santner-Nanan B, Jha MK, Schimpl A, Avots A and Serfling E (2002)
Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes. Blood
100 954-960 Schulze-Osthoff
K, Beyaert R, Vandvoorde V, Haegeman G and Fiers W (1993) Nordihydroguaiaretic
acid inhibition of NF-kB. EMBO Journal 12 3095-3104 Schulze-Osthoff
K, Beyaert R, Vandvoorde V, Haegeman G and Fiers W (1993) Depletion of the
mitochondrial electron transport abrogates the cytoxic and gene-inductive
effects of TNF. EMBO Journal 12 3095-3104 Schulze-Osthoff
K, Los M and Baeuerle PA (1995) Redox signalling by transcription factors
NF-kB and AP-1 in the immune system. Biochemical Pharmacology 50 735-741 Schulze-Osthoff
K, Storth C (2000) Induced proximity model attracts NF-kB researchers. Cell
Death & Differentiation 7 1025-1026 Schulze-Tanzil G, Mobasheri A, Sendzik J, John T and Shakibaei M (2004) Effects of curcumin (diferuloylmethane) on nuclear factor kB signaling in interleukin-1beta-stimulated chondrocytes. Annals of the New York Academy of Sciences 1030 578-586 Schumacher JA, Crockett DK, Elenitoba-Johnson KS and Lim MS (2007) Proteome-wide changes induced by the Hsp90 inhibitor, geldanamycin in anaplastic large cell lymphoma cells. Proteomics in press Schumacher
LY, Vo DD, Garban HJ, Comin-Anduix B, Owens SK, Dissettee VB, Glaspy JA,
McBride WH, Bonavida B, Economou JS and Ribas A (2006) Immunosensitization of
tumor cells to dendritic cell-activated immune responses with the proteasome
inhibitor bortezomib (PS-341, Velcade). Schumann J, Prockl J, Kiemer AK, Vollmar AM, Bang R and Tiegs G (2003) Silibinin protects mice from T cell-dependent liver injury. Journal of Hepatology 39 333-340 Schumann DM, Maedler K, Franklin I, Konrad D, Storling J, Boni-Schnetzler M, Bjinovci A, Kurre MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, Halban PA, Nandrup-Poulsen T, Wollhaiem CB and Donath MY (2007) The Fas pathway is involved in pancreatic beta cell secretory function. Proceedings of the National Academy Sciences USA in press Schumann J, Muhlen K, Kiemer AK, Vollmar AM and Tiegs G (2003) Parenchymal, But Not Leukocyte, TNF receptor 2 mediates T cell-dependent hepatitis in mice. Journal of Immunology 170 2129-2137 Schumm K, Rocha S, Caamano J and Perkins ND (2006) Regualtion of p53 tumour suppressor target gene expression by the p52 NF-kB subunit. EMBO Journal 25 4820-4832 Schupp N, Schinzel R, Heidland A and Stopper H (2005) Genotoxicity of advanced glycation end products: involvement of oxidative stress and of angiotensin II type 1 receptors. Annals of the New York Academy of Sciences 1043 685-695 Schutt P, Rebmann V, Brandhorst D Wiefelsputz J, Ebeling P, Opalka B, Seeber S, Nowrousian MR, Moritz T and Grosse-Wilde H (2008) The clinical significance of soluble human leukocyte antitgen class-I, ICTP, and RANKL molecules in multiple myeloma patients. Human Immunology 69 79-87
Schütze S,
Potthoff, Machleidt T, Berkovic D, Wiegmann and Krönke M (1992) TNF activates
NF-kB by phosphatidylcholine-specific phospholipase C-induced
"acidic" sphingomyelin breakdown. Cell 71 765-776 Schutze S, Tchikov V and Schneider-Brachert W (2008) Regulation of TNFR1 and CD95 signalling by receptor compartmentalization. Nature Reviews Molecular and Cellular Biology in press Schuur ER and
Baluda MA (1991) Proto-oncogene expression in avian hematopoietic tissues.
Oncogene 6 1409-1415 Schuurs TA, Morariu AM, Ottens PJ, 't Hart NA, Popma SH, Leuvenink HG and Ploeg RJ (2006) Time-dependent changes in donor brain death related processes. American Journal of Transplantation in press Schwab M, Reynders V, Loitsch S, Steinhilber D, Schroder O and Stein J (2008) The dietary histone deacetylase inhibitor sulforaphane induces human beta-defensin-2 in intestinal epithelial cells. Immunology in press Schwabe RF, Bataller R and Brenner DA (2003) Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration. American Journal of Physiology: Gastrointestinal Liver Physiology 285 G949-G958 Schwabe RF
and Brenner DA (2002) Role of glycogen synthase kinase-3 in TNF-alpha-induced
NF-kB activation and apoptosis in hepatocytes. American Journal of Physiology: Gastrointestinal Liver
Physiology
283 G204-G211 Schwabe RF,
Bennett BL, Manning AM and Brenner DA (2001) Differential role of IkB kinase 1
and 2 in primary rat hepatocytes. Hepatology 33 81-90 Schwabe RF and Brenner DA (2007) Nuclear factor-kB in the liver: friend or foe? Gastroenterology 132 2601-2604 Schwabe RF and Sakurai H (2005) IKKbeta phosphorylates p65 at S468 in transactivaton domain 2. FASEB Journal 19 1758-1760 Schwabe RF,
Schnabl B, Kweon YO and Brenner DA (2001) CD40 activates NF-kB and c-Jun
N-terminal kinase and enhances chemokine secretion on activated human hepatic
stellate cells. Journal of Immunology 166 6812-6819 Schwabe RF, Uchinami H, Qian T, Bennett BL, Lemasters JJ and Brenner DA (2004) Differential requirement for c-Jun NH2-terminal kinase in TNF-alpha- and Fas-mediated apoptosis in hepatocytes. FASEB Journal 18 720-722 Schwamborn J, Lindecke A, Elvers M, Horejschi V, Kerick M, Rafigh M, Pfeiffer J, Pruellage M, Kaltschmidt B and Kaltschmidt C (2003) Microarray analysis of tumor necrosis factor a induced gene expression in U373 human glioblastoma cells. BMC Genomics 4 46 Schwandner R,
Dziarski R, Wesche H, Rothe M and Kirschning CJ (1999) Peptidoglycan- and
lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2.
Journal of Biological Chemistry 274 17406-17409 Schwandner R,
Yamaguchi K and Cao Z (2000) Requirement of tumor necrosis factor
receptor-associated factor (TRAF)6 in interleukin 17 signal transduction.
Journal of Experimental Medicine 191 1233-1240 Schwaninger M, INta I and Herrmann O (2006) NF-kB signalling in cerebral ischaemia. Biochemical Society Transactions 34 1291-1294 Schwaninger
M, Sallmann S, Petersen N, Schneider A, Prinz S, Libermann TA and Spranger M
(1999) Bradykinin induces interleukin-6 expression in astrocytes through
activation of nuclear factor-kB. Journal of Neurochemistry 73 1461-1466 Schwartz EM,
Badorff C, Hiura TS, Wessely R, Badorff A, Verma IM and Knowlton KU (1998)
NF-kB-mediated inhibition of apoptosis is required for encephalomyocarditis
virus virulence: a mechanism of resistance in p50 knockout mice. Journal of
Virology 72 5654-5660 Schwartz RC
and Witte ON (1988) A recombinant murine retrovirus expressing v-rel is
cytopathic. Virology 165 182-192 Schwartz S, Beaulieu JF and Ruemmele FM (2005) Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth. Biochemical and Biophsyical Research Communications in press Schwartz SA,
Hernandez A and Evers BM (1999) The role of NF-kB/IkB proteins in cancer:
implications for novel treatment strategies. Surgical Oncology 8 143-153 Schwarz EM,
Badorff C, Hiura TS, Wessely R, Badorff A, Verma IM and Knowlton KU (1998)
NF-kB mediated inhibition of apoptosis is required for Encephalomyocarditis
Virus virulence: a mechanism of resistance in p50 knockout mice. Journal of
Virology 72 5654-5660 Schwarz EM,
Krimpenfort P, Berns A and Verma IM (1997) Immunological defects in mice with
a targeted disruption in Bcl-3. Genes & Development 11 187-197 Schwarz EM, Looney RJ, Drissi MH, O'Keefe RJ, Boyce BF, Xing L and Ritchlin CT (2006) Autoimmunity and bone. Annals of the New York Academy of Sciences 1068 275-283 Schwarz EM, Lu AP, Goater JJ, Benz EB, Kollias G, Rosier RN, Puzas JE and O’Keefe RJ (2000) Tumor necrosis factor-alpha/nuclear transcription factor-kappaB signaling in periprosthetic osteolysis. Journal of Orthopedic Research 18 472-480 Schwarz EM, Van Antwerp D and Verma IM (1996) Constitutive
phosphorylation of IkBa by casein kinase II occurs preferentially at serine
293: requirement for degradation of free IkBa. Molecular and Cellular Biology
16 3554-3559 Schwarz JA, Brokstein PB, Voolstra CR, Terry AY, Miller DJ, Szmant AM, Coffroth MA and Medina M (2008) Coral life history and symbiosis: functional genomic resources for two reef building Caribbean corals, Acropora palmata and Montastraea faveolata. BMC Genomics 9 97 Schwarz M and
Murphy PM (2001) Kaposi's sarcoma-associated herpesvirus G protein-coupled
receptor constitutively activates NF-kB and induces proinflammatory cytokine
and chemokine production via a C-terminal signaling determinant. Journal of
Immunology 167 505-513 Schwarz NT,
Engel B, Eskandari MK, Kalff JC, Grandis JR and Bauer AJ (2002)
Lipopolysaccharide preconditioning and cross-tolerance: the induction of
protective mechanisms for rat intestinal ileus. Gastroenterology 123 586-598 Schwarz SC,
Seufferlein T, Liptay S, Schmid RM, Kasischke K, Foster OJ, Daniel S and
Schwarz J (1998) Microglial activation in multiple system atrophy: a potential
role for NFkB/rel proteins. Neuroreport 9 3029-3032 Schwarzer N,
Nost R, Seybold J, Parida SK, Fuhrmann O, Krull M, Schmidt R, Newton R,
Hippenstiel S, Domann E, Chakraborty T and Suttorp N (1998) Two distinct
phospholipases C of Listeria monocytogenes induce ceramide generation, Nuclear
Factor-kB activation, and E-selectin expression in human endothelial cells.
Journal of Immunology 161 3010-3018 Schweers LA
and Sanders MM (1991) A protein with a binding specificity similar to NF-kB
binds to a steroid-dependent regulatory element in the ovalbumin gene. Journal
of Biological Chemistry 266 10490-10497 Schweighofer B, Schultes J, Pomyje J and HOfer E (2007) Signals and genes induced by angiogenic growth factors in comparison to inflammatory cytokines in endothelial cells. Clinical Hemorheology and Microcirculation 37 57-62 Schweikl H, Spagnuolo G and Schamlz G (2006) Genetic and cellular toxicology of dental resin monomers. Journal of Dental Research 85 870-877 Schweitzer K, Bozko PM, Dubiel W and Naumann M (2007) CSN controls NF-kB by deubiquitinylation of IkBa. EMBO Journal 26 1532-1541 Schwenger P,
Alpert D, Skolnik EY and Vilcek J (1998) Activation of p38 mitogen-activated
protein kinase by sodium salicylate leads to inhibition of tumor necrosis
factor-induced IkBa phosphorylation and degradation. Molecular and Cellular
Biology 18 78-84 Schwenger P,
Alpert D, Skolnik EY and Vilcek J (1999) Cell-type-specific activation of
c-Jun N-terminal kinase by salicylates. Journal of Cell Physiology 179 109-114 Schwenger V, Morath C, Salava A, Amann K, Seregin Y, Deppisch R, Ritz E, Bierhaus A, Nawroth PP and Zeier M (2005) Damage to the peritoneal membrane by glucose degradation products is mediated by the receptor for advanced glycation end-products. Journal of the American Society of Nephrology in press Schwenzer R,
Siemienski K, Liptay S, Schubert G, Peters N, Scheurich P, Schmid RM and
Wajant H (1999) The human tumor necrosis factor (TNF) receptor-associated
factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family
and modulates TNF-induced activation of NF-kB and c-Jun N-terminal kinase.
Journal of Biological Chemistry 274 19368-19374 Schwerdt G, Holzinger H, Sauvant C, Konigs M, Humpf HU and Geckle M (2007) Long-term effects of ochratoxin A on fibrosis and cell death in human proximal tubule or fibroblast cells in primary culture. Toxicology 232 57-67 Schwock J, Ho JC, Luther E, Hedley DW and Geddie WR (2007) Measurement of signaling Pathway activities in solid tumor fine-needle biopsies by slide-based cytometry. Diagnostic Molecular Pathology 16 130-140 Scibetta AG, Copier J, Barrett A, Chaplin T and Taylor-Papadimitriou J (2005) Gene expression changes induced by a recombinant e1/e3(-) adenovirus type 5 vector in human mammary epithelial cells. Intervirology 48 350-361 Scicchitano MS, McFarland DC, Tierney LA, Boyce RW, Frazier KS, Schwartz LW and Thomas HC (2007) Role of p38 in regulation of hematopoiesis: Effect of p38 inhibition on cytokine production and transcription factor activity in human bone marrow stromal cells. Blood, Cells, Molecules and Disease in press Sciortino MT, Medici MA, Marino-Merlo F, Zaccaria D, Giuffre M, Venuti A, Grelli S and Mastino A (2007) Signaling pathway used by HSV-1 to induce NF-kB activation: possible role of herpes virus entry receptor A. Annals of the New York Academy of Sciences 1096 89-96 Sciortino MT, Medici MA, Marino-Merlo F, Zaccaria D, Giuffre-Cuculletto M, Venuti A, Grelli S and Mastino A (2008) Involvement of HVEM receptor in activation of nuclear factor kappaB by herpes simplex virus 1 glycoprotein D. Cellular Microbiology 10 2297-2311 Sclabas GM, Fujioka S, Schmidt C, Fan Z, Evans DB and Chiao PJ (2003) Restoring apoptosis in pancreatic cancer Cells by targeting the nuclear factor-kB signaling pathway with the anti-epidermal growth factor antibody IMC-C225. Journal of Gastrointestinal Surgery 7 37-43 Sclabas GM, Uwagawa T, Schmidt C, Hess KR, Evans DB, Abbruzzese JL and Chiao PJ (2005) Nuclear factor kB activation is a potential target for preventing pancreatic carcinoma by aspirin. Cancer 103 2485-2490 Scortegagna M, Cataisson C, Martin RJ, Hicklin DJ, Schreiber RD, Yuspa Sh and Arbeit JM (2008) HIF-1a regulates epithelial inflammation by cell autonomous NFkB activation and paracrine stromal remodeling. Blood in press Scott BB, Zaratin PF, Gilmartin AG, Hansbury MJ, Colombo A, Belpasso C, Winkler JD and Jackson JR (2005) TNF-alpha modulates angiopoietin-1 expression in rheumatoid synovial fibroblasts via the NF-kB signalling pathway. Biochemical and Biophysical Research Communications 328 409-414 Scott ML,
Fujita T, Liou H-C, Nolan GP and Baltimore D (1993) The p65 subunit of NF-kB
regulates IkB by two distinct mechanisms. Genes & Development 7 1266-1276 Scott T and Oweens MD (2007) Thrombocytes respond to lipopolysaccharide through Toll-like receptor-4, and MAP kinase and NF-kB pathways leading to expression of interleukin-6 and cyclooxygenase-2 with production of prostaglandin E2. Molecular Immunology in press Scumpia PO, Sarcia PJ, Kelly KM, DeMarco VG and Skimming JW (2004) Hypothermia induces anti-inflammatory cytokines and inhibits nitric oxide and myeloperoxidase-mediated damage in the hearts of endotoxemic rats. Chest 125 1483-1491 Scupoli MT, Donadelli M, Cioffi F, Rossi M, Perbellini O, Malpeli G, Corbiioli S, Vinante F, Krampera M, Palmieri M, Scarpa A< ANola C, Foa R and Pizzolo G (2008) Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kB and JNK/AP-1 pathways. Haematologica in press Scupoli MT,
Fiorini E, Marchisio PC, Poffe O, Tagliabue E, Brentegani M, Tridente G and
Ramarli D (2000) Lymphoid adhesion promotes human thymic epithelial cell
survival via NF-(kappa)B activation. Journal of Cell Science 113 169-177 Seabra SH, de Souza W and Damatta RA (2004) Toxoplasma gondii exposes phosphatidylserine inducing a TGF-beta(1) autocrine effect orchestrating macrophage evasion. Biochemical and Biophysical Research Communications 324 744-752 Sears C,
Olesen J, Rubin D, Finley D and Maniatis T (1998) NF-kB p105 processing via
the ubiquitin-proteasome pathway. Journal of Biological Chemistry 273
1409-1419 Sebald A, Mattioli I and Schmitz ML (2005) T cell receptor-induced lipid raft recruitment of the IkB kinase complex is necessary and sufficient for NF-kB activation occurring in the cytosol. European Journal of Immunology 35 318-325 Sebastian C, Serra M, Yeramian A, Serrat N, Lloberas J adn Celada A (2008) Deacetylase Activity Is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells. Journal of Immunology 180 5898-5906 Sebban H and Courtois G (2006) NF-kB and inflammation in genetic disease. Biochemical Pharmacology 72 1153-1160 Sebban H, Yamaoka S and Courtois G (2006) Posttranslational modifications of NEMO and its partners in NF-kB signaling. Trends in Cell Biology 16 569-577 Sebban-Benin H, Pescatore A, Fusco F, Pascuale V, Gautheron J, Yamaoka S, Moncla A, Ursini MV and Courtois G (2007) Identification of Traf6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti. Human Molecular Genetics in press Sebens S, Arlt A and Schafer H (2008) NF-kB as a molecular target in the therapy of pancreatic carcinoma. Recent Results in Cancer Research 177 151-164 Sebens Muerkoster S, Rausch AV, Isberner A, Mikenberg J, Blaszczuk E, Witt M, Folsch UR, Schmitz F, Schafer H and Arlt A (2007) The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kB inhibition. Oncogene in press Sebkova L, Pellicano A, Monteleone G, Grazioli B, Guarnieri G, Imeneo M, Pallone F and Luzza F (2004) Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells. Infection and Immunity 72 5019-5026 Secchiero P, Corallini F, Barbarotto E, Melloni E, di Iasio MG, Tiribelli M and Zauli G (2005) Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells. Journal of Cellular Physiology 207 158-164 Secchiero P, Corallini F, di Iasio MG, Gonelli A, Barbarotto E and Zauli G (2005) TRAIL counteracts the pro-adhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release. Blood 105 3413-3419 Secchiero P, Corallini F, Gonelli A, Dell'eva R, Vitale M, Capitani S, Albini A and Zauli G (2006) Antiangiogenic activity of the MDM2 antagonist Nutlin-3. Circulation Research in press Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G and Zauli G (2007) Activation of the p53 pathway down-regulates the osteoprotegerin (OPG) expression and release by vascular endothelial cells. Blood in press Secchiero P, Gonelli A, Carnevale E, Milani D, Pandolfi A, Zella D and Zauli G (2003) TRAIL promotes the survival and proliferation of primary human vascular endothelial Cells by activating the Akt and ERK pathways. Circulation 107 2250-2256 Secchiero P, Milani D, Gonelli A, Melloni E, Campioni D, Gibellini D, Capitani S and Zauli G (2003) Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kB-dependent maturation of normal and leukemic myeloid cells. Journal of Leukocyte Biology 74 223-232 Seck T, Diel
I, Bismar H, Ziegler R and Pfeilschifter J (2001) Serum parathyroid hormone,
but not menopausal status, is associated with the expression of
osteoprotegerin and RANKL mRNA in human bone samples. European Jounral of
Endocrinology 145 199-205 Sedger LM,
Shows DM, Blanton RA, Peschon JJ, Goodwin RG, Cosman D and Wiley SR (1999)
IFN-gamma mediates a novel antiviral activity through dynamic modulation of
TRAIL and TRAIL receptor expression. Journal of Immunology 163 920-926 Sedimbi SK, Shastry A, Park Y, Rumba I and Sanjeevi CB (2006) Association of SUMO4 M55V polymorphism with autoimmune diabetes in Latvian patients. Annals of the New York Academy of Sciences 1079 273-277 See V, Rajala NK, Spiller DG and White MR (2004) Calcium-dependent regulation of the cell cycle via a novel MAPK-NF-kB pathway in Swiss 3T3 cells. Journal of Cell Biology 166 661-672 Seeliger S, Derian CK, Vergnolle N, Bunnett NW, Nawroth R, Schmelz M, Von Der Weid PY, Buddenkotte J, Sunderkotter C, Metze D, Andrade-Gordon P, Harms E, Vestweber D, Luger TA and Steinhoff M (2003) Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo. FASEB Journal 17 1871-1885 Seetharaman
R, Mora AL, Nabozny G, Boothby M and Chen J (1999) Essential role of T cell
NF-kB activation in collagen-induced arthritis. Journal of Immunology 163
1577-1583 Segaert S,
Courtois S, Garmyn M, Degreef H and Bouillon R (2000) The flavonoid apigenin
suppresses vitamin D receptor expression and vitamin D responsiveness in
normal human keratinocytes. Biochemical and Biophysical Research
Communications 268 237-241 Segain JP, Raingeard de la Bletiere D, Bourreille A, Leray V, Gervois N, Rosales C, Ferrier L, Bonnet C, Blottiere HM and Galmiche JP (2000) Butyrate inhibits inflammatory responses through NFkB inhibition: implications for Crohn’s disease. Gut 47 397-403 Segain JP, Raingeard De La Bletiere D, Sauzeau V, Bourreille A, Hilaret G, Cario-Toumaniantz C, Pacaud P, Galmiche JP and Loirand G (2003) Rho kinase blockade prevents inflammation via nuclear factor kappaB inhibition: evidence in Crohn's disease and experimental colitis. Gastroenterology 124 1180-1187 Segain JP, Rolli-Derkinderen M, Gervois N, Raingeard de Bletiere D, Loirand G and Pacaud P (2007) Z Urotensin II is a new chemotactic factor for UT receptor-expressing monocytes. Journal of Immunology 179 901-909 Segal-Bendirdjian E, Dudognon C, Mathieu J, Hillion J and Besancon F (2005) Cell death signalling: recent advances and therapeutic application [Article in French.] Bull Cancer 9 23-35 Segars JH, Nagata T, Bours V, Medin JA, Franzoso G,
Blanco JCG, Drew PD, Becker KG, An J, Tang T, Stephany DA, Neel B, Siebenlist
U and Ozato K (1993) Retinoic acid induction of major histocompatibility
complex class I genes in NTera-2 embryonal carcinoma cells involves induction
of NF-kB (p50-p65) and retinoic acid receptor b-retinoid X receptor b
heterodimers. Molecular and Cellular Biology 13 6157-6169 Segelmark M,
Barrett C, Pendergraft W, Falk R and Preston G (2000) Expression of
p300-truncated fragments results in the modulation of apoptosis in rat
mesangial cells. Kidney Int 57 1873-1881 Segev DL,
Hoshiya Y, Hoshiya M, Tran TT, Carey JL, Stephen AE, MacLaughlin DT, Donahoe
PK and Maheswaran S (2002) Mullerian-inhibiting substance regulates NF-kB
signaling in the prostate in vitro and in vivo. Proceedings of the National
Academy of Sciences USA 99 239-244 Segev DL,
Hoshiya Y, Stephen AE, Hoshiya M, Tran TT, MacLaughlin DT, Donahoe PK and
Maheswaran S (2001) Mullerian inhibiting substance regulates NFkB signaling
and growth of mammary epithelial cells in vivo. Journal of Biological
Chemistry 276 26799-26806 Seguin CA and Bernier SM (2003) TNFalpha suppresses link protein and type II collagen expression in chondrocytes: Role of MEK1/2 and NF-kB signaling pathways. Journal of Cell Physiology 197 356-369 Seguin CA, Bojarski M, PIlliar Rm, Roughley PJ and Kandel RA (2006) Differential regulation of matrix degrading enzymes in a TNFalpha-induced model of nucleus pulposus tissue degeneration. Matrix Biology in press Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R, Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E, Yuste VJ and Comella JX (2007) The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis. Journal of Neuroscience 27 11228-11241 Sehnert B, Gierer P, Ibrahim S, Kuhl A, Voll R, Nandakumar KS, Holmdahl R, Hallmann R, VOllmar B and Burkhardt H (2006) Modulation of granulocyte-endothelium interactions by antileukoproteinase: inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium. Arthritis Research and Therapy 8 R95 Seidel V,
Bailleul and Waterman PG (2000)
(Rel)-1beta,2alpha-di-(2,4-dihydroxy-6-methoxybenzoyl)-3beta,4alpha-di-(4-methoxyphenyl)-cyclobutane
and other flavonoids from the aerial parts of Goniothalamus gardneri and
Goniothalamus thwaitesii. Phytochemistry 55 439-446 Seidelin JB, Vainer B, Andresen L and Nielsen OH (2007) Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis. Virchows Archives in press Seino K,
Setoguchi Y, Ogino T, Kayagaki N, Akiba H, Nakano H, Taniguchi H, Takada Y,
Yuzawa K, Todoroki T, Fukuchi Y, Yagita H, Okumura K and Fukao K (2001)
Protection against Fas-mediated and tumor necrosis factor receptor 1-mediated
liver injury by blockade of FADD without loss of nuclear factor-kB activation.
Annals of Surgery 234 681-688 Seitz CS,
Deng H, Hinata K, Lin Q and Khavari PA (2000) Nuclear factor kB subunits
induce epithelial cell growth arrest. Cancer Research 60 4085-4092 Seitz CS,
Freiberg RA, Hinata K and Khavari PA (2000) NF-kB determines localization and
features of cell death in epidermis. Journal of Clinical Investigation 105
253-260 Seitz CS, Lin Q, Deng H and Khavari PA (1998) Alterations in NF-kB function in transgenic epithelial tissue demonstrates growth inhibitory role for NF-kB. Proceedings of the National Academy of Sciences USA 95 2307-2312 Sekalska B (2003) Aortic expression of monocyte chemotactic protein-1 (MCP-1) gene in rabbits with experimental atherosclerosis [Article in Polish]. Ann Acad Med Stetin 49 79-90
Seki E and Brenner DA (2007) The role of NF-kB in hepatocarcinogenesis:
Promoter or suppressor? Seki E and Brenner DA (2008) Toll-like receptors and adaptor molecules in liver disease: update. Hepatology in press Seki E, De Minicis S, Osterreicher CH, Kluwe J, Osawa Y, Brenner DA and Schwabe RF (2007) TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nature Medicine in press Seki E, Tsutsui H, Iimuro Y, Naka T, Son G, Akira S, Kishimoto T, Nakanishi K and Fujimoto J (2005) Contribution of Toll-like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration. Hepatology 41 443-450 Seki N, Hashimoto N, Sano H, Horiuchi S, Yagui K, Makino H and Saito Y (2003) Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells. Metabolism 52 1558-1563 Seki N,
Hashimoto N, Taira M, Yagi S, Yoshida Y, Ishikawa K, Suzuki Y, Sano H,
Horiuchi S, Yoshida S, Sakurai K, Yagui K, Makino H and Saito Y (2007)
Regulation of Src homology 2-containing protein tyrosine phosphatase by
advanced glycation end products: the role on atherosclerosis in diabetes. Sekido H, Suzuki T, Jomori T, Takeuchi M, Yabe-Nishimura C and Yagihashi S (2004) Reduced cell replication and induction of apoptosis by advanced glycation end products in rat Schwann cells. Biochemical and Biophysical Research Communications 320 241-248 Skeigawa I, Yanagida M, Iwabuchi K, Kaneda K, Kaneko H, Taksaki Y, Jung G, Sone S, Tanak Y, Ogawa H and Takamori K (2008) Protein biomarker analysis by mass spectrometry in patients with rheumatoid arthritis receiving anti-tumor necrosis factor-alpha antibody therapy. Clinical and Experimental Rheumatology 26 261-267 Sekine N,
Fukumoto S, Ishikawa T, Okazaki T and Fujita T (2001) GH inhibits
interferon-gamma-induced signal transducer and activator of transcription-1
activation and expression of the inducible isoform of nitric oxide synthase in
INS-1 cells. Endocrinology 142 3909-3916 Sekine Y, Yumioka T, Yamamoto T, Muromoto R, Imoto S, Sugiyama K, Oritani K, Smimoda K, Minoguchi M Akira S, Yoshimura A and Matsuda T (2006) Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages. Journal of Immunology 176 380-389 Sekiya M, Ueda K,Okazaki K, Kikuchi H, Kurata S and Oshima Y (2008) A cyclopentanediol analogue selectively suppresses the conserved innate immunity pathways, Drosophila IMD and TNF-alpha pathways. Biochemical Pharmacology in press Sekkai D,
Aillet F, Israel N and Lepoivre M (1998) Inhibition of NF-kB and HIV-1 long
terminal repeat transcriptional activation by inducible nitric oxide synthase
2 activity. Journal of Biological Chemistry 273 3895-3900 Seko Y (2007) Giant cell and Takayasu arteritis. Current Opinion in Rheumatology 19 39-43 Sela U, Dayan M, Hershkoviz R, Cahalon L, Lider O and Mozes E (2006) The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses. European Journal of Immunology 36 2971-2980 Seldon MP, Silva G, Pejanovic N, Larsen R, Gregoire IP, Filipe J, Anrather J and Soares MP )2007) Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kB RelA phosphorylation at serine 276. Journal of Immunology 179 7840-7851 Selkirk GA, McLellan TM, Wright HE and Rhind SG (2008) Mild endotoxemia, nuclear factor (NF)-kB translocation and cytokine increase during exertional heat stress in trained and untrained individuals. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology in press Selkirk GA, Wright HE, McLellan TM and Rhind SG (2007) Nuclear factor (NF)-kB activation in human peripheral blood mononuclear cells of trained versus untrained individuals during exertional heat stress. Medicien and Science in Sports and Exercise 39 S61 Sell H, Dietze-Schroeder D, Kaiser U and Eckel J (2006) MCP-1 is a potential player in the negative crosstalk between adipose tissue and skeletal muscle. Endocrinology 147 2458-2467 Sellers WR
and Fisher DE (1999) Apoptosis and cancer drug targeting. Journal of Clinical
Investigation 104 1655-1661 Selmi C, Montano N, Furlan R, Keen CL and Gershwin ME (2007) Inflammation and oxidative stress in obstructive sleep apnea syndrome. Experimental Biology and Medicine (Maywood) 232 1409-1413 Selvaraj SK, Periandythevar P aand Prasadarao NV (2007) Outer membrane protein A of Escherichia coli K1 selectively enhances the expression of intercellular adhesion molecule-1 in brain microvascular endothelial cells. Microbes and Infection 9 547-557 Selvaraj SK and Prasadarao NV (2005) Escherichia coli K1 inhibits proinflammatory cytokine induction in monocytes by preventing NF-kB activation. Journal of Leukocyte Biology in press Selvarajoo K (2006) Discovering differential activation machinery of the Toll-like receptor 4 signaling pathways in MyD88 knockouts. FEBS Letters 580 1457-1464 Selzman CH,
Shames BD, McIntyre RC Jr, Banerjee A and Harken AH (1999) The NFkB
inhibitory peptide, IkBa, prevents human vascular smooth muscle proliferation.
Annals of Thoracic Surgery 67 1227-1231; discussion 1231-1222 Selzman CH,
Shames BD, Reznikov LL, Miller SA, Meng X, Barton HA, Werman A, Harken AH,
Dinarello CA and Banerjee A (1999) Liposomal delivery of purified
inhibitory-kBalpha inhibits tumor necrosis factor-alpha-induced human vascular
smooth muscle proliferation. Circulation Research 84 867-875 Semba RD, Lauretani F and Ferrucci L (2007) Carotenoids as protection against sarcopenia in older adults. Archives of Biochemistry and Biophysics 458 141-145 Sembries S,
Pahl H, Stilgenbauer S, Dohner H and Schriever F (1999) Reduced expression of
adhesion molecules and cell signaling receptors by chronic lymphocytic
leukemia cells with 11q deletion. Blood 93 624-631 Semlali A, Oliva J, Badia E, Pons M and Duchesne MJ (2004) Immediate early gene X-1 (IEX-1), a hydroxytamoxifen regulated gene with increased stimulation in MCF-7 derived resistant breast cancer cells. Journal of Steroid Biochemistry and Molecular Biology 88 247-259 Semmler M, Seeck U, Neustadt B, Schulz M, Dotzlaw H, Neeck G and Eggert M (2007) No effects of adalimumab therapy on the activation of NF-kB in lymphocytes from patients with severe rheumatoid arthritis. Clinical Rheumatology in press Semnani RT, Venugopal PG, Leifer CA, Mostbock S, Sabzevari H and Nutman TBG (2008) Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites. Blood in press Semple
JI,
Brown SE, Sanderson CM and Campbell RD (2002) A distinct bipartite motif is
required for the localization of inhibitory kB-like (IkBL) protein to nuclear
speckles. Biochemical Journal 361 489-496 Sen CK and
Bagchi D (2001) Regulation of inducible adhesion molecule expression in human
endothelial cells by grape seed proanthocyanidin extract. Mol Cell Biochem 216
1-7 Sen CK and
Packer L (1996) Antioxidant and redox regulation of gene transcription. FASEB
Journal 10 709-720 Sen CK and Roy S (2005) Relief from a heavy heart: redox-sensitive NF-kB as a therapeutic target in managing cardiac hypertrophy. American Journal of Physiology: Heart and Circulatory Physiology 289 H17-H19 Sen CK,
Tirosh O, Roy S, Kobayashi MS and Packer L (1998) A positively charged
a-lipoic acid analogue with increased cellular uptake and more potent
immunomodulatory activity. Biochemical and Biophysical Research Communications
247 223-228 Sen CK,
Traber K and Packer L (1996) Inhibition of NF-kB activation in human T-cell
lines by anetholdithiolthione. Biochemical and Biophysical Research
Communications 218 148-153 Sen G, Bikah G, Venkataraman C and Bondada S (1999) Negative regulation of antigen receptor-mediated signaling by constitutive association of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells. European Journal of Immunology 29 3319-3328 Sen GC and Sarkar SN (2005) Transcriptional signaling by double-stranded RNA: role of TLR3. Cytokine and Growth Factor Reviews 16 1-14 Sen J (2002) The CARMA of NF-kB. Trends in Immunology 23 570
Sen J, Venkataraman L, Shinkai Y, Pierce JW, Alt FW, Burakoff SJ and Sen R (1995)
Expression and induction of nuclear factor-kB-related proteins in thymocytes.
Journal of Immunology 154 3213-3221 Sen P, Bhattacharyya S, Wallet M, Wong CP, Poligone B, Sen M, Baldwin AS Jr and Tisch R (2003) NF-kB hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages. Journal of Immunology 170 1770-1780 Sen P, Chakraborty PK and Raha S (2006) Activation of p38MAPK by repetitive low-grade oxidative stress leads to pro-survival effects. Biochimica et Biophysica Acta in press Sen P, Wallet MA, Yi Z, Huang Y, Henderson M, Mathews CE, Earp HS, Matsushima G, Baldwin Jr AS and Tisch RM (2006) Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-{kappa}B activation in dendritic cells. Blood in press Sen R (2004) NF-kB and the immunoglobulin kappa gene enhancer. Journal of Experimental Medicine 200 1099-1102 Sen R (2006) Control of B lymphocyte apoptosis by the transcription factor NF-kB. Immunity 25 871-883
Sen R and
Baltimore D (1986) Inducibility of k immunoglobulin enhancer-binding protein
NF-kB by a post-translational mechanism. Cell 47 921-928 Sen R and
Baltimore D (1986) Multiple nuclear factors interact with the immunoglobulin
enhancer sequences. Cell 46 705-716 Sen S, Sharma H and Singh N (2005) Curcumin enhances Vinorelbine mediated apoptosis in NSCLC cells by the mitochondrial pathway. Biochemical and Biophysical Research Communications 331 1245-1252 Senf SM, Dodd SL, McClung JM and Judge AR (2008) Hsp70 overexpression inhibits NF-kB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy. FASEB Journal in press Senftleben U (2003) NF-kB in critical diseases: a bad guy? Intenisve Care Medicine 29 1873-1876 Senftleben U
and Karin M (2002) The IKK/NF-kB pathway. Crit Care Med 30 S18-S26 Senftleben U,
Cao Y, Xiao G, Greten FR, Krahn G, Bonizzi G, Chen Y, Hu Y, Fong A, Sun S-C,
Karin M (2001) Activation by IKKalpha of a second, evolutionary conserved,
NF-kB signalling pathway. Science 293 1495-1499 Senftleben U,
Li ZW, Baud V and Karin M (2001) IKKb is essential for protecting T cells from
TNFa-induced apoptosis. Immunity 14 217-230 Sengchanthalangsy
LL, Datta S, Huang D-B, Anderson E, Braswell EH and Ghosh G (1999)
Characterization of the dimer interface of transcription factor NFkB
homodimer. Journal of Molecular Biology 289 1029-1040 Senger K, Armstrong GW, Rowell WJ, Kwan JM, Markstein M and Levine M (2004) Immunity regulatory DNAs share common organizational features in Drosophila. Molecular Cell 13 19-32 Senger K, Harris K and Levine M (2006) GATA factors participate in tissue-specific immune responses in Drosophila larvae. Proceedings of the National Academy of Sciences USA 103 15957-15962 Sengul S, Zwizinski C and Batuman V (2003) Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells. American Journal of Physiology: Renal Physiology 284 F1245-F1254 Sengul S, Zwizinski C, Simon EE, Kapasi A, Singhal PC and Batuman V (2002) Endocytosis of light chains induces cytokines through activation of NF-kB in human proximal tubule cells. Kidney International 62 1977-1988 Sensky PL, Jewell KK, Ryan KJ, Parr T, Bardsley RG and Buttery PJ (2006) Effect of anabolic agents on calpastatin promoters in porcine skeletal muscle and their responsiveness to cyclic adenosine monophosphate-and calcium-related stimuli. Journal of Animal Science 84 2973-2982 Seo AY, Hofer T, Sung B, Judge S, Chung HY and Leeuwenburgh C (2006) Hepatic oxidative stress during aging: effects of 8% long-term calorie restriction and lifelong exercise. Antioxidant and Redox Signaling 8 529-538 Seo
HJ, Park
KK, Han SS, Chung WY, Son MW, Kim WB and Surh YJ (2002) Inhibitory effects of
the standardized extract (DA-9601) of Artemisia asiatica Nakai on phorbol
ester-induced ornithine decarboxylase activity, papilloma formation,
cyclooxygenase-2 expression, inducible nitric oxide synthase expression and
nuclear transcription factor kB activation in mouse skin. International
Journal of Cancer 100 456-462 Seo JH, Kim H and Kim KH (2002) Cyclooxygenase-2 expression by Transcription Factors in Helicobacter pylori-infected gastric epithelial cells: comparison between HP 99 and NCTC 11637. Annals of the New York Academy of Sciences 973 477-480 Seo JH, Lim JW, Kim H and Kim KH (2003) Helicobacter pylori in a Korean isolate activates mitogen-activated protein kinases, AP-1, and NF-kB and induces chemokine expression in gastric epithelial AGS cells. Laboratory Investigation 84 49-62 Seo JY, Kim H and Kim KH (2002) Transcriptional regulation by thiol compounds in Helicobacter pylori-induced interleukin-8 production in human gastric epithelial cells. Annals of the New York Academy of Sciences 973 541-545 Seo KH, Ko HM, Choi JH, Jung HH, Chun YH, Choi IW, Lee HK and Im SY (2004) Essential role for platelet-activating factor-induced NF-kB activation in macrophage-derived angiogenesis. European Journal of Immunology 34 2129-2137 Seo KH, Ko HM, Kim HA, Choi JH, Park SJ, Kim KJ, Lee HK and Im SY (2006) Platelet-activating factor induces up-regulation of antiapoptotic factors in a melanoma cell line through nuclear factor-kB activation. Cancer Research 66 4681-4686 Seo KH, Lee HS, Jung B, Ko HM, Choi JH, Park SJ, Choi IH, Lee HK and Im SY (2004) Estrogen enhances angiogenesis through a pathway involving platelet-activating factor-Mediated nuclear factor-kB activation. Cancer Research 64 6482-6488 Seo M, Park M, Yook Y, Kwon YS, Suh YJ, Kim MJ, Cho D and Park JH (2008) IL-18 gene expression pattern in exogenously treated AML cells. BMB Reports 41 461-465 Seo SB, Jeong HJ, Chung HS, Lee JD, You YO, Kajiuchi T and Kim HM (2003) Inhibitory Effect of High molecular weight water-soluble chitosan on hypoxia-induced inflammatory cytokine production. Biol Pharm Bull 26 717-721 Seo SH and
Webster RG (2002) Tumor necrosis factor alpha exerts powerful anti-influenza
virus effects in lung epithelial cells. Journal of Virology 76 1071-1076 Seo SW, Jung WS, Lee SE, Choi CM, Shin BC, Kim EK, Kwon KB, Hong SH, Yun KJ, Park RK, Shin MK, SOng HJ and Park SJ (2008) Effects of bee venom on cholecystokinin octapeptide-induced acute pancreatitis in rats. Pancrease 36 e22-e29 Seo SW, Jung WS, Piao TG, Hong SH, Yun KJ, Park RK, Shin MK, Song HJ and Park SJ (2007) Selective cyclooxygenase-2 inhibitor ameliorates cholecystokinin-octapeptide-induced acute pancreatitis in rats. World Journal of Gastroenterology 13 2298-2304 Seo SW, Lee D, Cho SK, Kim AD, Minematsu H, Celil Aydemir AB, Geller JA, Macaulay W, Yang J and Young-In Lee F (2007) ERK signaling regulates macrophage colony-stimulating factor expression induced by titanium particles in MC3T3.E1 murine calvarial preosteoblastic cells. Annalsof the New York Academy of Sciences 1117 151-158 Seo T, Park J, Lim C and Choe J (2004) Inhibition of nuclear factor kappaB activity by viral interferon regulatory factor 3 of Kaposi's sarcoma-associated herpesvirus. Oncogene 23 6146-6155 Seo WG, Pae
HO, Oh GS, Chai KY, Yun YG, Kwon TO and Chung HT (2000) Inhibitory effect of
ethyl acetate fraction from Cudrania tricuspidata on the expression of nitric
oxide synthase gene in RAW 264.7 macrophages stimulated with interferon-gamma
and lipopolysaccharide. General Pharmacology 35 21-28 Seok YM, Kim J, Park MJ, Boo YC, Park YK and Park KM (2008) Wen-pi-tang-Hab-Wu-ling-san attenuates kidney fibrosis induced by ischemia/reperfusion in mice. Phytotherapy Research in press Seppanen M,
Henttinen T, Lin L, Punnonen J, Grenman S, Punnonen R and Vihko KK (1998)
Inhibitory effects of cytokines on ovarian and endometrial carcinoma cells in
vitro with special reference to induction of specific transcriptional
regulators [published erratum appears in Oncol Res 1999;11(2):105-8]. Oncology
Research 10 575-589 Seppanen M,
Lin L, Punnonen J, Grenman S, Punnonen R and Vihko KK (2000) Regulation of
UT-OC-3 ovarian carcinoma cells by cytokines: inhibitory effects on cell
proliferation and activation of transcription factors AP-1 and NF-kB. European
Journal of Endocrinology 142 393-401 Seppanen O, Glumoff V, Paananen R, Rounioja S and Hallman M (2004) Transcription factors NF-kB and C/EBPdelta and IL-1-induced expression of surfactant protein A in lung explants during the perinatal period. Biology of the Neonate 87 152-159 Sepulveda MA, Emelyanov AV and Birshtein BK (2004) NF-kB and Oct-2 synergize to activate the human 3' Igh hs4 enhancer in B cells. Journal of Immunology 172 1054-1064 Serafica MD, Goto T and Trounson AO (2005) Transcripts from a human primordial follicle cDNA library. Human Reproduction 20 2074-2091 Serandour AL, Loyer P, Garnier D, Courselaud B, Theret N, Glaise D, Guguen-Guillouzo C and Corlu A (2005) TNFalpha-mediated extracellular matrix remodeling is required for multiple division cycles in rat hepatocytes. Hepatology 41 478-486 Serfling E, Berberich-Siebelt F, Avots A, Chuvpilo S, Klein-Hessling S, Jha MK, Kondo E, Pagel P, Schulze-Luehrmann J and Palmetshofer A (2004) NFAT and NF-kB factors-the distant relatives. International Journal of Biochemistry and Cell Biology 36 1166-1170 Serio KJ, Johns SC, Luo L, Hodulik CR and Bigby TD (2003) Lipopolysaccharide down-regulates the leukotriene C(4) synthase gene in the monocyte-like cell line, THP-1. Journal of Immunology 170 2121-2128 Serio
KJ, Reddy KV and Bigby TD (2005) Lipopolysaccharide induces 5-lipoxygenase
activating protein gene expression in THP-1 cells via a NF-kB and C/EBP-mediated
mechanism. Seriwatanachai D, Thongchote K, Charoenphandhu N, Pandaranandaka J, Tudpor K, Teerapornpuntakit J, Suthiphongchai T aand Krishnamra N (2007) Prolactin directly enhances bone turnover by raising osteoblast-expressed receptor activator of nuclear factor kB ligand/osteoprotegerin ratio. Bone in press Serkkola E
and Hurme M (1993) Activation of NF-kB by cAMP in human myeloid cells. FEBS
Letters 334 327-330 Serracino-Inglott
F, Habib NA and Mathie RT (2001) Hepatic ischemia-reperfusion injury. American
Journal of Surgery 181 160-166 Serrano-Mollar A, Closa D, Prats N, Blesa S, Martinez-Losa M, Cortijo J, Estrela JM, Morcillo EJ, Bulbena O (2003) In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats. British Journal of Pharmacology 138 1037-1048 Serri O, Li L, Mamputu JC, Beauchamp MC, Maingrette F and Renier G (2006) The influences of hyperprolactinemia and obesity on cardiovascular risk markers: effects of cabergoline therapy. Clinical Endocrinology (Oxford) 64 366-370 Servant M, Grandvaux N and Hiscott J (2002) Multiple signaling pathways leading to the activation of interferon regulatory factor 3. Biochemical Pharmacology 64 985-992 Servant MJ,
ten Oever B, LePage C, Conti L, Gessani S, Julkunen I, Lin R and Hiscott J
(2001) Identification of distinct signaling pathways leading to the
phosphorylation of interferon regulatory factor 3. Journal of Biological
Chemistry 276 355-363 Seseke F, Thelen P and Ringert RH (2004) Characterization of an animal model of spontaneous congenital unilateral obstructive uropathy by cDNA microarray analysis. European Urology 45 374-381 Seta N, Okazaki Y and Kuwana M (2008) Human circulating monocytes can express receptor activator of nuclear factor-kB ligand and differentiate into functional osteoclasts without exogenous stimulation. Immunology Cell Biology in press Seth P, Mahajan VS and Chauhan SS (2003) Transcription of human cathepsin L mRNA species hCATL B from a novel alternative promoter in the first intron of its gene. Gene 321 83-91 Seth RB, Sun L and Chen ZJ (2006) Antiviral innate immunity pathways. Cell Research 16 141-147 Seth RB, Sun L, Ea CK and Chen ZJ (2005) Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kB and IRF3. Cell 122 669-682 Sethi G, Ahn KS and Aggarwal BB (2008) Targeting nuclear factor-kB activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis. Molevcular Cancer Research 6 1059-1070 Sethi G, Ahn KS, Chaturvedi MM and Aggarwal BB (2007) Epidermal growth factor (EGF) activates nuclear factor-kB through IkBa kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkBa. Oncogene 26 7324-7332 Sethi G, Ahn KS, Pandey MK and Aggarwal BB (2007) Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kB-regulated gene products and TAK1-mediated NF-kB activation. Blood 109 2727-2735 Sethi G, Ahn KS, Sandur SK, Lin X, Chaturvedi MM and Aggarwal BB (2006) Indirubin enhances TNF-induced apoptosis through modulation of nuclear factor-kB signaling pathway. Journal of Biological Chemistry 281 23425-23435 Sethi G, Ahn KS, Sung B and Aggarwal BB (2008) Pinitol targets nuclear factor-kB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis. Molecular Cancer Therpaeutics 7 1604-1614 Sethi G, Ahn KS, Sung B, Kunnumakkara AB, Chaturvedi MM and Aggarwal BB (2008) SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkBa kinase activation. Biochemical Pharmacology in press Sethi G, Ahn KS, Xia D, Kurie JM and Aggarwal BB (2007) Targeted deletion of MKK4 gene Potentiates TNF-induced apoptosis through the down-regulation of NF-kB activation and NF-kB-regulated antiapoptotic gene products. Journal of Immunology 179 1926-1933 Sethi G and Sodhi A (2004) In vitro activation of murine peritoneal macrophages by ultraviolet B radiation: upregulation of CD18, production of NO, proinflammatory cytokines and a signal transduction pathway. Molecular Immunology 40 1315-1323 Sethi G, Sung B and Aggarwal BB (2008) Nuclear factor-kB activation: from bench to bedside. Experimental Biology and Medicine (Maywood) 233 21-31 Sethi S (2002) Inhibition of leukocyte-endothelial interactions by oxidized omega-3 fatty acids: a novel mechanism for the anti-inflammatory effects of omega-3 fatty acids in fish oil.Redox Rep 7 369-378 Seto M Kim S,
Yoshitusa H, Nakamura Y, Masuda T, Hamaguchi A, Yamanaka S and Iwao H (1998)
Effects of prednisolone on glomerular signal transduction cascades in
experimental glomerulohephritis. Journal of the American Society of Nephrology
9 1367-1376 Setoguchi K,
Misaki Y, Terauchi Y, Yamauchi T, Kawahata K, Kadowaki T and Yamamoto K (2001)
Peroxisome proliferator-activated receptor-gamma haploinsufficiency enhances B
cell proliferative responses and exacerbates experimentally induced arthritis.
Journal of Clinical Investigation 108 1667-1675 Setty AR and Sigal LH (2005) Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects. Seminars in Arthritis and Rheumatism 34 773-784 Severa M, D'Ambrosio A, Giordani L, Quintieri F and Coccia E (2005) Inhibition of interleukin-12 expression in diltiazem-treated dendritic cells through the reduction of nuclear factor-kappaB transcriptional activity. Biochemical Pharmacology 69 425-432 Severa M and Fitzgerald KA (2007) TLR-mediated activation of type I IFN during antiviral immune responses: fighting the battle to win the war. Current Topics in Microbiology and Immunology 316 167-192 Sevilla L,
Zaldumbide A, Pognonec P and Boulukos KE (2001) Transcriptional regulation of
the bcl-x gene encoding the anti-apoptotic Bcl-xL protein by Ets, Rel/NFkB,
STAT and AP1 transcription factor families. Histology and Histopathology 16 595-601 Sevoian M,
Larose RN and Chamberlain DM (1964) Avian lymphomatosis.VI. A virus of unusual
potency and pathogenicity. Avian Diseases 8 336-347 Sevoian M,
Larose RN and Chamberlain DM (1964) Avian lymphomatosis.VIII. Pathological
response of the chicken embryo to T-virus. Journal of the National Cancer
Institute Monograph 17 99-119 Sexton DW (2008) Targeting airway inflammation: PMX464 and the epithelial bulls eye. British Journal of Pharmacology in press Seya T, Oshiumi H, Sasai M, Akazawa T and Matsumoto M (2005) TICAM-1 and TICAM-2: toll-like receptor adapters that participate in induction of type 1 interferons. International Journal of Biochemistry and Cell Biology 37 524-529 Seydel KB, Li
E, Zhang Z and Stanley Jr SL (1998) Epithelial cell-initiated inflammation
plays a crucial role in early tissue damage in amebic infection of human
intestine. Gastroenterology 115 1446-1453 Seaymour R, Sundberg JP and Hogenesch H (2006) Abnormal lymphoid organ development in immunodeficient mutant mice. Veterinary Pathology 43 401-423 Sezer O (2005) Myeloma bone disease. Hematology 10 19-24 Sezer O, Heider U, Zavrski I, Kuehne CA and Hofbauer LC (2002) RANK ligand and osteoprotegerin in myeloma bone disease. Blood 101 2094-2098 Sgarbanti M, Arguello M, TenOever BR, Battistini A, Lin R and Hiscott J (2004) A requirement for NF-kB induction in the production of replication-competent HHV-8 virions. Oncogene 23 5770-5780 Sgarbanti M, Marsili G, Remoli AL, Orsatti R, and Battistini A (2007) IRF-7: new role in the regulation of genes involved in adaptive immunity. Annals of the New York Academy of Sciences 1095 325-333 Sgarbanti M, Marsili G, Remoli AL, Ridolfi B, Stellacci E, Borsetti A, Ensoli B and Battistini A (2004) Analysis of the signal transduction pathway leading to human immunodeficiency virus-1-induced interferon regulatory factor-1 upregulation. Annals of the New York Academy of Sciences 1030 187-195 Sgarbanti M, Remoli AL, Marsili G, Ridolfi B, Borsetti A, Perrotti E, Orsatti R, Ilari R, Sernicola L, Stellacci E, Ensoli B and Battistini A (2008) IRF-1 is required for full NF-kB transcriptional activity at the HIV-1 LTR enhancer. Journal of Virology in press Sha WC (1998) Regulation of immune responses by
NF-kB/Rel transcription factor. Journal of
Experimental Medicine 187 143-146 Sha WC, Liou
H-C, Tuomanen EI and Baltimore D (1995) Targeted disruption of the p50 subunit
of NF-kB leads to multifocal defects in immune responses. Cell 80 321-330 Shaarawy M, Fathy SA, Mehany NL and Hindy OW (2007) Circulating levels of osteoprotegerin and receptor activator of NF-kB ligand in patients with chronic renal failure. Clinical Chemistry and Laboratory Medicine 45 1498-1503 Shackelford
DA, Tobaru T, Zhang S and Zivin JA (1999) Changes in expression of the DNA
repair protein complex DNA-dependent protein kinase after ischemia and
reperfusion. Journal of Neuroscience 19 4727-4738 Shackelford
RE, Alford PB, Xue Y, Thai S-F, Adams DO and Pizzo S (1997) Aspirin inhibits
tumor necrosis factor-a gene expression in murine tissue macrophages.
Molecular Pharmacology 52 421-429 Shaffer AL,
Rosenwald A, Hurt EM, Giltnane JM, Lam LT, Pickeral OK and Staudt LM (2001)
Signatures of the immune response. Immunity 15 375-385 Shaffer AL, Rosenwald A and Staudt LM (2002) Decision making in the immune system: Lymphoid malignancies: the dark side of B-cell differentiation. Nature Reveiws Immunology 2 920-933 Shaffer AL, Wright G, Yang L, Powell J, Ngo V, Lamy L, Lam LT, Davis RE and Staudt LM (2006) A library of gene expression signatures to illuminate normal and pathological lymphoid biology. Immunological Reviews 210 67-85
Shah IM, Lees
KR, Pien CP and Elliott PJ (2002) Early clinical experience with the novel
proteasome inhibitor PS-519. British Journal of Clinical Pharmacology 54
269-276 Shah N and Scanlan TS (2004) Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands. Bioorganic Medicinal Chemistry Letters 14 5199-5203 Shah N,
Thomas T, Lewis JS, Klinge CM, Shirahata A, Gelinas C and Thomas T (2001)
Regulation of estrogenic and nuclear factor kB functions by polyamines and
their role in polyamine analog-induced apoptosis of breast cancer cells.
Oncogene 20 1715-1729 Shah N,
Thomas T, Shirahata A, Sigal LH and Thomas TJ (1999) Activation of nuclear
factor kB by polyamines in breast cancer cells. Biochemistry 38 14763-14774 Shah N,
Thomas TJ, Lewis JS, Klinge CM, Shirahata A, Gelinas C and Thomas T (2001)
Regulation of estrogenic and nuclear factor kappa B functions by polyamines
and their role in polyamine analog-induced apoptosis of breast cancer cells.
Oncogene 20 1715-1729 Shah R, Gonzales F, Golez E, Augustin D, Caudillo S, Abbott A, Morello J, McDonough P, Paolini P and Shubeita H (2005) The antidiabetic agent rosiglitazone upregulates SERCA2 and Enhances TNF-alpha- and LPS-induced NF-kB-dependent transcription and TNF-alpha-induced IL-6 secretion in ventricular myocytes. Cell Physiology and Biochemistry 15 41-50 Shah SA, Mahmud N, Mftah M, Roche HM and Kelleher D (2006) Chronic but not acute conjugated linoleic acid treatment inhibits deoxycholic acid-induced protein kinase C and nuclear factor-kB activation in human colorectal cancer cells. European Journal of Cancer Prevention 15 125-133 Shah SA,
Potter MW, Hedeshian MH, Kim RD, Chari RS and Callery MP (2002) PI-3' kinase
and NF-kB cross-signaling in human pancreatic cancer cells. Journal of
Gastrointestinal Surgery 5 603-613 Shah SA,
Potter MW, McDade TP, Ricciardi R, Perugini RA, Elliott PJ, Adams J and
Callery MP (2001) 26S proteasome inhibition induces apoptosis and limits
growth of human pancreatic cancer. Journal of Cellular Biochemistry
82 110-122
Shah SA, Volkov Y, Arfin Q, Abdel-Latiff MM and Kelleher D (2005) Ursodeoxycholic acid inhibits interleukin beta 1 and deoxycholic acid-induced activation of NF-kB and AP-1 in human colon cancer cells. International Journal of Cancer 118 532-539 Shah SJ and Sylvester PW (2005) gamma-Tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kB activity. Experimental Biology and Medicine (Maywood) 230 235-241 Shah TJ and Walsh SW (2007) Activation of NF-kB and expression of COX-2 in association with neutrophil infiltration in systemic vascular tissue of women with preeclampsia. American Journal of Obstetrics and Gynecology 196 48.e1-48e1.8 Shah Y, Ma X, Morimura K, Kim I and Gonzalez FJ (2007) Pregnane X receptor activation ameliorates DSS-induced IBD via inhibition of NFkB target gene expression. American Journal of Physiology: Gastrointestinal and Liver Physiology in press Shajahan Miah SM, Hughes TL and Campbell KS (2008) Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkB-inducing kinase in stromal cells. Journal of Immunology 180 2922-2932 Shahrestanifar
M, Fan X and Manning DR (1999) Lysophosphatidic acid activates NF-kB in
fibroblasts. A requirement for multiple inputs. Journal of Biological
Chemistry 274 3828-3833 Shaaikh IA, Brown I, Schofield AC, Wahle KW and Heys SD (2008) Docosahexaenoic acid enhances the efficacy of docetaxel in prostate cancer cells by modulation of apoptosis: The role of genes associated with the NF-kB pathway. Prostate in press Shain KH,
Jove R and Olashaw NE (1997) Constitutive RelB activation in v-Src-transformed
fibroblasts: requirement for IkB degradation. Journal of Cellular Biochemistry
73 237-247 Shakibaei M, Csaki C, Mebrich S and Mobasheri A (2008) Resveratrol suppresses interleukin-1beta-induced inflammatory signaling and apoptosis in human articular chondrocytes: Potential for use as a novel nutraceutical for the treatment of osteoarthritis. Biochemical Pharmacology in press Shakibaei M, John T, Schulze-Tanzil G, Lehmann I and Mobasheri A (2007) Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: implications for the treatment of osteoarthritis. Biochemical Pharmacology in press Shakoori A, Ougolkov A, Yu ZW, Zhang B, Modarressi MH, Billadeau DD, Mai M, Takahashi Y and Minamoto T (2005) Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation. Biochemical and Biophysical Research Communications 334 1365-1374 Shakoory B, Fitzgerald SM, Lee SA, Chi DS, Krishnaswamy G (2004) The role of human mast cell-derived cytokines in eosinophil biology. Journal of Interferon and Cytokine Research 24 271-281 Shakov AN,
Collart MA, Vassalli P, Nedospasov SA and Jongeneel CV (1990) kB-type
enhancers are involved in lipopolysaccharide-mediated transcriptional
activation of the tumor necrosis factor a gene in primary macrophages. Journal
of Experimental Medicine 171 35-47 Shalini S and Bansal MP (2007) Co-operative effect of glutathione depletion and selenium induced oxidative stress on API and NFkB expression in testicular cells in vitro: insights to regulation of spermatogenesis. Biological Research 40 307-317 Shalit I, Halperin D, Haite D, Levitov A, Romano J, Osherov N and Fabian I (2006) Anti-inflammatory effects of moxifloxacin on IL-8, IL-1beta and TNF-a secretion and NFkB and MAP-kinase activation in human monocytes stimulated with Aspergillus fumigatus. Journal of Antimicrobial Chemotherapy 57 230-235 Shalom-Barak
T, Quach J and Lotz M (1998) Interleukin-17-induced gene expression in
articular chondrocytes is associated with activation of mitogen-activated
protein kinases and NF-kB. Journal of Biological Chemistry 273 27467-27473 Shambhjarkar PB, Blonska M, Pappu BP, Li H, You Y, Sakurai H, Darnay BG, Hara H, Penninger J and Lin X (2007) Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways. EMBO Journal 26 1794-1805 Shames BD,
Barton HH, Reznikov LL, Cairns CB, Banerjee A, Harken AH and Meng X (2002)
Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the
myocardium. Shock 17 114-119 Shames BD,
McIntyre Jr RC, Bensard DD, Pulido EJ, Selzman CH, Reznikov LL, Harken AH
and Meng X (2001) Suppression of tumor necrosis factor alpha production by
cAMP in human monocytes: dissociation with mRNA level and independent of
interleukin- 10. Journal of Surgical Research 99 187-193 Shames BD,
Meldrum DR, Selzman CH, Pulido EJ, Cain BS, Banerjee A, harken AH and Meng X
(1998) Increased levels of myocardial IkB-a protein promote tolerance to
endotoxin. American Journal of Physiology 275 H1084-H1091 Shames BD,
Selzman CH, Meldrum DR, Pulido EJ, Barton HA, Meng X, Harken AH and McIntyre
RC Jr (1998) Interleukin-10 stabilizes inhibitory kB-a in human monocytes.
Shock 10 389-394 Shames BD,
Selzman CH, Meng X, Meldrum DR, Cain BS and Harken AH (1998) Genes don't
count. Archives of Surgery 133 667-669 Shames BD,
Selzman CH, Pulido EJ, Meng X, Meldrum DR, McIntyre RC, Jr, Harken AH and
Banerjee A (1999) LPS-Induced NF-kB activation and TNF-a release in human
monocytes are protein tyrosine kinase dependent and protein kinase C
independent. Journal of Surgical Research 83 69-74 Shammas MA, Neri P, Koley H, Batchu RB, Bertheau RC, Munshi V, Prabhala R, Fulciniti M, Tai YT, Treon SP, Goyal RK, Anderson KC and Munshi NC (2006) Specific killing of multiple myeloma cells by (-)- epigallocatechin-3-gallate extracted from green tea: biological activity and therapeutic implications. Blood 108 2804-2810 Shamshiev AT, Ampenberger F, Ernst B, Rohrer L, Marsland BJ and Kopf M (2007) Dyslipidemia inhibits Toll-like receptor-induced activation of CD8{alpha}-negative dendritic cells and protective Th1 type immunity. Journal of Experimental Medicine 204 441-452 Shan D, Fang Y, Ye Y and Liu J (2008) EGCG reducing the susceptibility to cholesterol gallstone formation through the regulation of inflammation. Biomedical Pharmacotherapy in press Shan SW, Tang MK, Cai DQ, Chui YL, Chow PH, Grotewold L and Lee KK (2005) Comparative proteomic analysis identifies protein disulfide isomerase and peroxiredoxin 1 as new players involved in embryonic interdigital cell death. Developmental Dynamics 233 266-281 Shan W, Nicol CJ, Ito S, Bility MT, Kennett MJ, Ward JM, Gonzalez FJ and Peters JM (2007) Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice. Hepatology in press Shan W, Palkar PS, Murray IA, McDevitt EI, Kennett MJ, Kang BH, Isom HC, Perdew GH, Gonzalez FJ and Peters JM (2008) Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by down-regulating pro-inflammatory gene expression. Toxicological Sciences in press Shan X, Hu A, Veler H, Fatma S, Grunstein JS, Chuang S and Grunstein MM (2006) Regulation of Toll-like receptor 4-induced pro-asthmatic changes in airway smooth muscle function by opposing actions of ERK1/2 and p38 MAPK signaling. American Journal of Physiology: Lung Cell and Molecular Physiology 291 L324-L333 Shan Y, Su Y, Luo X and Yang Z (2002) The significance of the expression of endothelial ICAM-1 induced by LPS [Article in Chinese]. Zhonghua Shao Shang Za Zhi 18 279-281 Shan YX, Jin SZ, Liu XD, Liu Y and Liu SZ (2006) Ionizing radiation stimulates secretion of pro-inflammatory cytokines: dose-response relationship, mechanisms and implications. Radiation and Environmental Biophysics 46 21-29 Shaneyfelt ME, Burke AD, Graff JW, Jutila MA nad Hardy ME (2006) Natural products that reduce rotavirus infectivity identified by a cell-based moderate-throughput screening assay. Virology Journal 3 68
Shang C,
Attema J, Cakouros D, Cockerill PN and Shannon MF (1999) Nuclear factor of
activated T cells contributes to the function of the CD28 response region of
the granulocyte macrophage-colony stimulating factor promoter. International
Immunology 11 1945-1956 Shang J,
Eberle J, Geilen CC, Hossini AM, Fecker LF, Orfanos CE and Tebbe B (2002) The
role of nuclear factor-kB and melanogenesis in tumor necrosis
factor-alpha-induced apoptosis of normal human melanocytes. Skin Pharmacol
Appl Skin Physiol 15 321-329 Shang LL, Sanyal S, Pfahnl AE, Jiao Z, Allen J,Liu H and DuDley SC (2007) NF-kB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II. American Journal of Physiology: Cellular Physiology in press Shankar S, Ganapathy S, Chen Q and Srivastava RK (2008) Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis. Molecular Cancer 7 16 Shankar S and Srivastava RK (2004) Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resistance Updates 7 139-156 Shanmugam N, Figarola JL, Li Y, Swiderski PM, Rahbar S and Natarajan R (2007) Pro-inflammatory effects of advanced lipoxidation end products in monocytes. Diabetes in press Shanmugam N, Gaw Gonzalo IT and Natarajan R (2004) Molecular mechanisms of high glucose-induced cyclooxygenase-2 expression in monocytes. Diabetes 53 795-802 Shanmugam N, Reddy MA, Guha M and Natarajan R (2003) High glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells. Diabetes 52 1256-1264 Shao DZ, Lee JJ, Huang WT, Liao JF and Lin MT (2004) Inhibition of nuclear factor-kB prevents staphylococcal enterotoxin A-induced fever. Molecular and Cellular Biochemistry 262 177-185 Shao H, Shen Y, Liu H, Dong G, Qiang J and Jing H (2007) Simvastatin suppresses lung inflammatory response in a rat cardiopulmonary bypass model. Annals of Thoracic Surgery 84 2011-2018 Shao J,
Fujiwara T, Kadowaki Y, Fukazawa T, Waku T, Itoshima T, Yamatsuji T, Nishizaki
M, Roth JA and Tanaka N (2000) Overexpression of the wild-type p53 gene
inhibits NF-kB activity and synergizes with aspirin to induce apoptosis in
human colon cancer cells. Oncogene 19 726-736 Shao R, Hu
MC, Zhou BP, Lin SY, Chiao PJ, von Lindern RH, Spohn B and Hung MC (1999) E1A
sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition
of IkB kinases and nuclear factor kB activities. Journal of Biological
Chemistry 274 21495-21498 Shao R,
Karunagaran D, Zhou BP, Li, K, Lo S-S, Deng J, Chiao P and Hung M-C (1997)
Inhibition of nuclear factor-kB activity is involved in E1A-mediated
sensitization of radiation-induced apoptosis. Journal of Biological Chemistry
272 32739-32742 Shao R, Tsai
EM, Wei K, von Lindern R, Chen YH, Makino K and Hung M-C (2001) E1A inhibition
of radiation-induced NF-kB activity through suppression of IKK activity and
IkB degradation, independent of Akt activation. Cancer Research 61 7413-7416 Shao RH, Tian X, Gorgun G, Urbano AG and Foss FM (2002) Arginine butyrate increases the cytotoxicity of DAB(389)IL-2 in leukemia and lymphoma cells by upregulation of IL-2Rbeta gene. Leukemia Research 26 1077-1083 Shao XT, Feng L, Yao HP, Sun WJ and Zhang LH (2004) Effect of Triptolide on TNFalpha-induced activation of NF-kB and expression of COX-2 and iNOS in human rheumatoid arthritis synovial fribroblasts [Article in Chinese]. Zhejiang Da Xue Xue Bao Yi Xue Ban 33 160-165 Shapira S, Harb OS, Caamano J and Hunter CA (2004) The NF-kB signaling pathway: immune evasion and immunoregulation during toxoplasmosis. International Journal of Parasitology 34 393-400 Shapira S, Harb OS, Margarit J, Matrajt M, Han J, HoffmannA, Freedman B, Jay MJ, Roos DS and Hunter CA (2005) Initiation and termination of NF-kB signaling by the intracellular protozoan parasite Toxoplasma gondii. Journal of Cell Science 118 3501-3508 Shapira S,
Speirs K, Gerstein A, Caamano J and Hunter CA (2002) Suppression of NF-kB
activation by infection with Toxoplasma gondii. Journal of Infectious Disease
185 S66-S72 Shapiro L,
Pott GB and Ralston AH (2001) Alpha-1-antitrypsin inhibits human
immunodeficiency virus type 1. FASEB Journal 15 115-122 Shapiro L,
Puren AJ, Barton HA, Novick D, Peskind RL, Shenkar R, Gu Y, Su MS and
Dinarello CA (1998) Interleukin 18 stimulates HIV type 1 in monocytic cells.
Proceedings of National Academy of Sciences USA 95 12550-12555 Shapiro RS and Anderson KV (2006) Drosophila Ik2, a member of the IkB kinase family, is required for mRNA localization during oogenesis. Development 133 1467-1475 Shapiro VS,
Mollenauer MN, Greene WC and Weiss A (1996) c-rel regulation of IL-2 gene
expression may be mediated through activation of AP-1. Journal of Experimental
Medicine 184 1663-1669 Shareef MM, Brown B, Shajahan S, Sathishkumar S, Arnold SM, Mohiuddin M, Ahmed MM and Spring PM (2008) Lack of P-glycoprotein expression by low-dose fractionated radiation results from loss of nuclear factor-kB and NF-Y activation in oral carcinoma cells. Molecular Cancer Research 6 89-98 Shareef MM, Cui N, Burikhanov R, Gupta S, Satishkumar S, Shajahan S, Mohiuddin M, Rangnekar VM and Ahmed MM (2007) Role of tumor necrosis factor-alpha and TRAIL in high-dose radiation-induced bystander signaling in lung adenocarcinoma. Cancer Research 67 11811-11820 Sharfi O, Bolshakov VN, Raines S, Newham P and Perkins ND (2007) Transcriptional profiling of the LPS induced NF-kB response in macrophages. BMC Immunology 8 1 Sharif MN, Sosic D, Rthlin CV, Kelly E, Lemke G, Olson EN and Ivashik LB (2006) Twist mediates supression of inflammation by type I IFNs and Axl. Journal of Experimental Medicine 203 1891-1901 Sharipo A,
Imreh M, Leonchiks A, Imreh S and Masucci MG (1998) A minimal glycine-alanine
repeat prevents the interaction of ubiquitinated IkBa with the proteasome: a
new mechanism for selective inhibition of proteolysis. Nature Medicine 4
939-944 Sharma AC (2007) Sepsis-induced myocardial dysfuncation. Shock in press Sharma C, Kaur J, Shishodia S, Aggarwal BB and Falhan R (2006) Curcumin down regulates smokeless tobacco-induced NF-kB activation and COX-2 expression in human oral premalignant and cancer cells. Toxicology 228 1-15 Sharma CS, Sarkar S, Periyakaruppan A, Ravichandran P, Sadanandan B, Ramesh V, Thomas R, Hall JC, Wilson Bl and Ramesh GT (2008) Simulated microgravity activates apoptosis and NF-kB in mice testis. Molecular and Cellular Biochemistry in press Sharma H, Sen S, Sheriff AK, Bal S, Mathur M and Singh N (2003) Characterization of apoptosis-related molecular changes in a desmoid tumor of the chest wall: report of a case. Surgery Today 33 358-362 Sharma M, Arnason JT and Hudson JB (2006) Echinacea extracts modulate the production of multiple transcription factors in uninfected cells and rhinovirus-infected cells. Phytotherapy Research 20 1074-1079 Sharma M, George AA, Singh BN, Sahoo NC and Rao KV (2007) Regulation of transcript elongation through cooperative and ordered recruitment of cofactors. Journal of Biological Chemistry in press Sharma RK, Chopra S, Sharma SD, Pande V, Ramos MJ, Merguro K, Inoue JI and Otsuka M (2006) Biological evaluation, chelation, and molecular mdeling studies of novel metal-chelating Inhibitors of NF-kB-DNA binding: structure activity relationships. Journal of Medicnal Chemistry 49 3595-3601 Sharma RK, Otsuka M, Pande V, Inoue JI and Joao Ramos M (2004) Evans Blue is an inhibitor of nuclear factor-kB (NF-kB) DNA binding. Bioorganic Medicinal Chemistry Letters 14 6123-6127 Sharma RK, Pande V, Ramos MJ, Rajor HK, Chopra S, Meguro K, Inoue J and Otsuka M (2005) Inhibitory activity of polyhydroxycarboxylate chelators against recombinant NF-kB p50 protein-DNA binding. Bioorganic Chemistry 33 67-81
Sharma RP,
Bhandari N, Riley RT, Voss KA and Meredith FI (2000) Tolerance to fumonisin
toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor.
Toxicology 143 183-194 Sharma RV,
Gurjar MV and Bhalla RC (2001) Selected contribution: estrogen receptor-alpha
gene transfer inhibits proliferation and NF-kB activation in VSM cells from
female rats. Journal of Applied Physiology 91 2400-2406 Sharma S,
Grandvaux N, Mamane Y, Genin P, Azimi N, Waldmann T and Hiscott J (2002)
Regulation of IFN regulatory factor 4 expression in human T cell leukemia
virus-I-transformed T cells. Journal of Immunology 169 3120-3130 Sharma S and Lichtenstein A (2008) Dexamethasone induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors. Blood in press Sharma S, TenOever BR, Grandvaux N, Zhou GP, Lin R and Hiscott J (2003) Triggering the interferon antiviral response through an IKK-related pathway. Science 300 1148-1151 Sharma SD, Meeran SM and Katiyar SK (2007) Dietary grape seed proanthocyanidins inhibit UVB-induced oxidative stress and activation of mitogen-activated protein kinases and nuclear factor-{kappa}B signaling in in vivo SKH-1 hairless mice. Molecular Cancer Therapy 6 995-1005 Sharma SM, Bronisz A, Hu R, Patel K, Mansky KC, Sif S and Ostrowski MC (2007) MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. Journal of Biological Chemistry in press Sharma V, Hupp CD and Tepe JJ (2007) Enhancement of chemotherapeutic efficacy by small molecule inhibition of NF-kB and checkpoint kinases. Current Medicinal Chemistry 14 1061-1074 Sharma V, Lansdell TA, Peddibhotla S and Tepe JJ (2004) Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines. Chemistry & Biology 11 1689-1699 Sharma V, Peddibhotla S and Tepe JJ (2006) Sensitization of cancer cells to DNA damaging agents by imidazolines. Journal of the American Chemical Society 128 9137-9143 Shashidhar S, Lorente G, Nagavarapu U, Nelson A, Kuo J, Cummins J, Nikolich K, Urfer R and Foehr ED (2005) GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion. Oncogene 24 1673-1682 Shaul JD, Faina A and Huxford T (2008) The human IKKb subunit kinase domain displays CK2-like phosphorylation specificity. Biochemical and Biophysical Research Communications in press Shaulian
E and Karin M (2001) AP-1 in cell proliferation and survival. Oncogene 20 2390-2400 Shaw J, Zhang T, Rzeszutek M, Yurkova N, Baetz D, Davie JR and Kirschenbaum LA (2006) Transcriptional silencing of the death gene BNIP3 by cooperative action of NF-kB and histone deacetylase 1 in ventricular myocytes. Circulation Research 99 1347-1354 Shaw MH, Reimer T, Kim YG and Nunez GF (2008) NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Current Opinions in Immunology in press Shcherbakov AM, Lobanova YS, Shatskaya VA, Onopchenko OV, Gaspar'yan AV, Gershtein ES and Krasil'nikov MA (2006) Sensitization of MCF-7 breast cancer cells to the apoptotic effect of estradiol. Bulletin of Experimental Biology and Medicine 141 357-360 She H, Xiong
S, Lin M, Zandi E, Giulivi C and Tsukamoto H (2002) Iron activates NF-kB in
Kupffer cells. American Journal of Physiology: Gastrointestinal and Liver Physiology 283 G719-G726 Shea-Eaton
WK, Lee PP and Ip MM (2001) Regulation of milk protein gene expression in
normal mammary epithelial cells by tumor necrosis factor. Endocrinology 142
2558-2568 Sheedy FJ and O'Neill LA (2007) The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling. Journal of Leukocyte Biology in press Sheehan M,
Wong HR, Hake PW and Zingarelli B (2002) Protective effects of isohelenin, an
inhibitor of nuclear factor kB, in endotoxic shock in rats. Journal of Endotoxin
Research 8 99-107 Sheehan M, Wong HR, Hake PW and Zingarelli B (2003) Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis. Critical Care Medicine 31 2263-2270 Sheehan M,
Wong HR, Hake PW, Malhotra V, O'Connor M and Zingarelli B (2002) Parthenolide,
an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular
derangement and outcome in endotoxic shock in rodents. Molecular Pharmacology
61 953-963 Sheehy AM and
Schlissel MS (1999) Overexpression of RelA causes G1 arrest and apoptosis in a
pro-B cell line. Journal of Biological Chemistry 274 8708-8716 Sheen CH, Schleimer RP and Kulka M (2007) Codeine induces human mast cell chemokine and cytokine production: involvement of G-protein activation. Allergy 62 532-528 Shehata M, Shehata M, Shehata F and Pater A (2004) Dual apoptotic effect of Xrel3 c-Rel/NF-kB homolog in human cervical cancer cells. Cell Biology International 28 895-904 Shehata M, Shehata M, Shehata F and Pater A (2005) Apoptosis effects of Xrel3 c-Rel/nuclear factor-kB homolog in human cervical cancer cells. Cell Biology International 29 429-440 Shehata MF (2005) Rel/Nuclear factor kappaB apoptosis pathways in human cervical cancer cells. Cancer Cell International 5 10 Sheikh MS and Huang Y (2003) Death receptor activation complexes: it takes two to activate TNF Receptor 1. Cell Cycle 2 550-552 Sheikh S, Rahman M, Gale Z, Luu NT, Stone PC, Matharu NM, Rainger GE and Nash GB (2005) Differing mechanisms of leukocyte recruitment and sensitivity to conditioning by shear stress for endothelial cells treated with tumour necrosis factor-a or interleukin-1b. British Journal of Pharmacology 145 1052-1061 Sheldrick EL, Derecka K, Marshall E, Chin EC, Hodges L, Wathes DC, Abayasekara DR and Flint AP (2007) Peroxisome proliferator-activated receptors and the control of levels of prostaglandin-endoperoxide synthase 2 by arachidonic acid in the bovine uterus. Biochemical Journal in press Shelest E, Kel A, Goessling E and Wingender E (2002) Prediction of potential C/EBP/NF-kappaB composite elements using matrix-based search methods. In Silico Biology 3 7
Shelton CA
and Wasserman SA (1993) pelle encodes a protein kinase required to
establish dorsoventral polarity in the Drosophila embryo. Cell 89 7861-7865 Shelton MD, Kern TS and Mieyal JJ (2007) Glutaredoxin regulates nuclear factor kB and intercellular adhesion molecule in Muller cells: model of diabetic retinopathy. Journal of Biological Chemistry 282 12467-12474 Shembade N, Harhaj NS, Liebl DJ and Harhaj EW (2007) Essential role for TAX1BP1 in the termination of TNF-a-, IL-1- and LPS-mediated NF-kB and JNK signaling. EMBO Journal 26 3910-3922 Shembade N, Harhaj NS, Parvatiyar K, Copeland NG, Jenkins NA, Matesic LE and Harhaj EW (2008) The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nature Immunology in press Shembade N, Harhaj NS, Yamamoto M, Akira S and Harhaj EW (2007) The HTLV-I Tax oncoprotein requires the ubiquitin conjugating enzyme Ubc13 for NF-kB activation. Journal of Virology in press Shen B, Hagiwara M, Yao YY, Chao L and Chao J (2008) Salutary effect of kallistatin in salt-induced renal injury, inflammation, and fibrosis via antioxidative stress. Hypertension in press Shen B and
Manley JL (2002) Pelle kinase is activated by autophosphorylation during Toll
signaling in Drosophila. Development 129 1925-1933 Shen B, Yu J, Wang S, Chu ES, Wong VW, Zhou X, Lin G, Sung JJ and Chan HL (2007) Phyllanthus urinaria ameliorates the severity of nutritional steatohepatitis both in vitro and in vivo. Hepatology in press Shen C-H and
Stavnezer J (1998) Interaction of Stat6 and NF-kB: direct association and
synergistic activation of interleukin-4-induced transcription. Molecular and
Cellular Biology 18 3395-3404 Shen F, Chen SJ, Dong XJ, Zhong H, Li YT, Cheng GF (2003) Suppression of IL-8 gene transcription by resveratrol in phorbol ester treated human monocytic cells. Journal of Asian Natural Products Research 5 151-157 Shen F and Cheng GF (2001) Progresses in IkB kinase and related signal transduction [Article in Chinese]. Sheng Li Ke Xue Jin Zhan 32 80-82 Shen F, Hu Z, Goswami J and Gaffen SL (2006) Identification of common transcriptional regulatory elements in interleukin-17 target genes. Journal of Biological Chemistry 281 24138-24148 Shen G, Jeong WS, Hu R and Kong AN (2005) Regulation of Nrf2, NF-kB, and AP-1 signaling pathways by chemopreventive agents. Antioxidants and Redox Signaling 7 1648-1663 Shen H, Chen
ZJ, Zilfou JT, Hopper E, Murphy M and Tew KD (2001) Binding of the aminothiol
WR-1065 to transcription factors influences cellular response to anticancer
drugs. J Pharmacol Exp Ther 297 1067-1073 Shen H and Lentsch AB (2004) Progressive dysregulation of the transcription factors, NF-kB and STAT1, in prostate cancer cells causes pro-angiogenic Production of CXC chemokines. American Journal of Physioloigy: Cellular Physiology 286 C840-C847 Shen
H, Nelson G, Nelson DE, Kennedy S, Spiller DG, Griffiths T, Paton N, Oliver SG,
WHite MR and Kell DB (2006) Automated tracking of gene expression in
individual cells and cell compartments. Shen HM and Pervaiz S (2006) TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB Journal 20 1589-1598 Shen J,
Channavajhala P, Seldin DC and Sonenshein GE (2001) Phosphorylation by the
protein kinase CK2 promotes calpain-mediated degradation of IkBa. Journal of
Immunology 167 4919-4925 Shen K, Thomas VK, Dustin ML and Kam LC (2008) Micropatterning of costimulatory ligands enhances CD4+ T cell function. Proceedings of the National Academcy of Sciences USA in press Shen LQ, Liang HP, Lu FL, Xu X, Li SM, Hu CX and Li L (2004) Cloning and identification of NF-kB p50 Rel homology domain and detection of its autonomous reporter gene activity [Article in Chinese]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20 419-421 Shen LQ, Xu X, LIang HP and Li SM (2007) Screening of polypeptides interacting with Rel homology domain of NF-kB p50 subunit [Article in Chinese]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 23 804-806 Shen Q and Brown PH (2003) Novel agents for the prevention of breast cancer: targeting transcription factors and signal transduction pathways. Journal of Mammary Gland Biology and Neoplasia 8 45-73 Shen S, Yu S, Binek J, Chalimoniuk M, Zhang X, Lo SC, Hannink M, Wu J, Fritsche K, Donato R, Sun GY (2005) Distinct signaling pathways for induction of type II NOS by IFNgamma and LPS in BV-2 microglial cells. Neurochemistry International 47 298-307 Shen W and Ladisch S (2002) Ganglioside G(D1a) impedes lipopolysaccharide-induced maturation of human dendritic cells. Cellular Immunology 220 125-133 Shen W,
Waldschmidt M, Zhao X, Ratliff T and Krieg AM (2002) Antitumor mechanisms of
oligodeoxynucleotides with CpG and polyG motifs in murine prostate cancer
cells: decrease of NF-kB and AP-1 binding activities and induction of
apoptosis. Antisense Nucleic Acid Drug Dev 12 155-164 Shen W, Zhang
C and Zhang G (2002) Nuclear factor kB activation is mediated by NMDA and non-NMDA receptor and L-type voltage-gated Ca(2+) channel following severe
global ischemia in rat hippocampus. Brain Research 933 23-30 Shen WH, Zhang CY and Zhang GY (2003) Modulation of IkB kinase autophosphorylation and activity following brain ischemia. Acta Pharmacologica Sinica 24 311-315 Shen WH, Zhang CY and Zhang GY (2003) Antioxidants attenuate reperfusion injury after global brain ischemia through inhibiting nuclear factor-kB activity in rats. Acta Pharmacol Sin 24 1125-1130 Shen YC, Wang YH, Chou YC, Liou KT, Yen JC, Wang WY and Liao JF (2008) Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation. Journal of Neurochemistry 104 558-572 Shen Z, Crotti TN, Flannery MR, Matsuzaki K, Goldrign SR and McHugh KP (2007) A novel promoter regulates calcitonin receptor gene expression in human osteoclasts. Biochimica et Biophysica Acta 769 659-667
Shen Z,
Peedikayil J, Olson GK, Siebert PD and Fang Y (2002) Multiple transcription
factor profiling by enzyme-linked immunoassay. Biotechniques 32 1168-1177 Sheng WS, Hu S, Lokensgard JR and Peterson PK (2003) U50,488 inhibits HIV-1 Tat-induced monocyte chemoattractant protein-1 (CCL2) production by human astrocytes. Biochem Pharmacol 65 9-14 Shenkar R and
Abraham E (1999) Mechanisms of lung neutrophil activation after hemorrhage or
endotoxemia: roles of reactive oxygen intermediates, NF-kB, and cyclic AMP
response element binding protein. Journal of Immunology 163 954-962 Shenkar R,
Yum HK, Arcaroli J, Kupfner J and Abraham E (2001) Interactions between CBP,
NF-kB, and CREB in the lungs after hemorrhage and endotoxemia. Am J Physiol
Lung Cell Mol Physiol 281 L418-426. Shepard LW,
Yang M, Xie P, Browning DD, Voyno-Yasenetskaya T, Kozasa T and Ye RD (2001)
Constitutive activation of NF-kB and secretion of IL-8 induced by the G
protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involves
G{alpha}(13) and RhoA. Journal of Biological Chemistry 276 45979-45987 Shephard P, Hinz B, Smola-Hess S, Meister JJ, Krieg T and Smola H (2004) Dissecting the roles of endothelin,TGF-beta and GM-CSF on myofibroblast differentiation by keratinocytes. Thromb Haemost 92 262-274 Shephard P, Martin G, Smola-Hess S, Brunner G, Krieg T and Smola H (2004) Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. American Journal of Pathology 164 2055-2066 Sheppard AM,
McQuillan JJ, Iademarco MF and Dean DC (1995) Control of vascular adhesion
molecule-1 gene promoter activity during neural differentiation. Journal of
Biological Chemistry 270 3710-3719 Sheppard K-A,
Phelps KM, Williams AJ, Thanos D, Glass CK, Rosenfeld MG, Gerritsen ME and
Collins T (1997) Nuclear integration of glucocorticoid receptor and Nuclear
Factor-kB signaling by CREB-binding protein and steroid receptor
coactivator-1. Journal of Biological Chemistry 273 29291-29294 Sheppard K-A,
Rose DW, Haque ZK, Kurokawa R, McInerney E, Westin S, Thanos D, Rosenfeld MG,
Glass Ck and Collins T (1999) Transcriptional activation by NF-kB requires
multiple coactivators. Molecular and Cellular Biology 19 6367-6378 Sheridan GK, Pickering M, Twomey C, Moynagh PN, O'Connor JJ and Murphy KJ (2007) NF-kB activity in distinct neural subtypes of the rat hippocampus: Influence of time and GABA antagonism in acute slice preparations. Learning and Memory 14 525-532 Sherrill JD and Miller WE (2006) G protein-coupled receptor (GPCR) kinase 2 regulates agonist-independent Gq/11 signaling from the mouse cytomegalovirus GPCR M33. Journal of Biological Chemistry 281 39796-39805 Shetty A and Forbes A (2002) Pharmacogenomics of response to anti-tumor necrosis factor therapy in patients with Crohn's disease. American Journal of Pharmacogenomics 2 215-221 Shetty S,
Gladden JB, Henson ES, Hu X, Villanueva J, Haney N and Gibson SB (2002) Tumor
necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death
receptor 5 (DR5) mediated by NFkB activation in epithelial derived cell lines.
Apoptosis 7 413-420 Sheu JN, Lin TH, Lii CK, Chen CC, Chen HW and Liu KL (2005) Contribution of conjugated linoleic acid to the suppression of inducible nitric oxide synthase expression and transcription factor activation in stimulated mouse mesangial cells. Food Chemistry and Toxicology 44 409-416 Sheu ML, Chao KF, Sung YJ, Lin WW, Lin-Shiau SY and Liu SH (2005) Activation of phosphoinositide 3-kinase in response to inflammation and nitric oxide leads to the up-regulation of cyclooxygenase-2 expression and subsequent cell proliferation in mesangial cells. Cellular Signaling 17 975-984 Sheu ML, Chiang CK, Tsai KS, Ho FM, Weng TI, Wu HY and Liu SH (2008) Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis. Free Radical Biology and Medicine in press Sheu ML, Ho FM, Chao KF, Kuo ML and Liu SH (2004) Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kB activation and cyclooxygenase-2 expression in mesangial cells. Molecular Pharmacology 66 187-196 Sheu ML, Ho FM, Yang RS, Chao KF, Lin WW, Lin-Shiau SY and Liu SH (2005) High glucose Induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway. Arteriosclerosis, Thrombosis and Vascular Biology 25 539-545 Sheu WH, Chang TM, Lee WJ, Ou HC, Wu CM, Tseng LN, Lang HF, Wu CS, Wan CJ and Lee IT (2008) Effect of weight loss on proinflammatory state of mononuclear cells in obese women. Obesity (Silver Spring) in press Shi C, Zhang
X, Chen Z, Robinson MK and Simon DI (2001) Leukocyte integrin Mac-1 recruits
toll/interleukin-1 receptor superfamily signaling intermediates to modulate
NF-kB activity. Circulation Research 89 859-865 Shi C, Zhao X, Lagergren A, Sigvardsson M, Wang X and Andersson R (2006) Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis. Scandinavian Jounral of Gastroenterology 41 472-480 Shi C, Zhao X, Wang X and Andersson R (2005) Role of nuclear factor-kB, reactive oxygen species and cellular signaling in the early phase of acute pancreatitis. Scandinavian Journal of Gastroenterology 40 103-108 Shi CS and
Kehrl JH (2001) PYK2 links G(q)alpha and G(13)alpha signaling to NF-kB
activation. Journal of Biological Chemistry 276 31845-31850 Shi CS,
Leonardi A, Kyriakis J, Siebenlist U and Kehrl JH (1999) TNF-mediated
activation of the stress-activated protein kinase pathway: TNF
receptor-associated factor 2 recruits and activates germinal center kinase
related. Journal of Immunology 163 3279-3285 Shi D and Jiang BH (2002) Antioxidant properties of apple juice and its protection against Cr(VI)-induced cellular injury. J Environ Pathol Toxicol Oncol 21 233-242 Shi JH, Xu XP, Zhang ZL, Zhang JS, Ge JB and Cheng WY (2003) Inhibition of activation of nuclear factor-kB enhanced apoptosis of leukemic cells induced by homoharringtonine [Article in Chinese]. Zhonghua Nei Ke Za Zhi 42 292-295 Shi M, Deng W, Bi E, Mao K, Ji Y, Lin G, Wu X, Tao Z, Li Z, Cai X, Sun S, Xiang C and Sun B (2008) TRIM30a negatively regulates TLR-mediated NF-kB activation by targeting TAB2 and TAB3 for degradation. Nature Immunology 9 369-377 Shi MJ, Park
SR, Kim PH and Stavnezer J (2001) Roles of Ets proteins, NF-kB and
nocodazole in regulating induction of transcription of mouse germline Ig alpha
RNA by transforming growth factor-beta 1. Interntational Immunology 13 733-746 Shi MM, Chong
I, Godleski JJ and Paulauskis JD (1999) Regulation of macrophage inflammatory
protein-2 gene expression by oxidative stress in rat alveolar macrophages.
Immunology 97 309-315 Shi Q, Benderdour M, Lavigne P, Ranger P and Fernandes JC (2006) Evidence for two distinct pathways in TNFa-induced membrane and soluble forms of ICAM-1 in human osteoblast-like cells isolated from osteoarthritic patients. Osteoarthritis Cartilage 15 300-308 Shi Q and Gibson GE (2007) Oxidative stress and transcriptional regulation in Alzheimer disease. Zlzheimers Disease and Associated Disorders 21 276-291 Shi Q, Le X,
Abbruzzese JL, Wang B, Mujaida N, Matsushima K, Huang S, Xiong Q and Xie K
(1999) Cooperation between transcription factor AP-1 and NF-kB in the
induction of interleukin-8 in human pancreatic adenocarcinoma cells by
hypoxia. Journal of Interferon and Cytokine Research 19 1363-1371 Shi RX, Ong CN and Shen HM (2004) Luteolin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells. Oncogene 23 7712-7721 Shi S, Nathan C, Schnappinger D, Drenkow J, Fuortes M, Block E, Ding A, Gingeras TR, Schoolnik G, Akira S, Takeda K and Ehrt S (2003) MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis. Journal of Experimental Medicine 198 987-997 Shi T, Liu WZ, Gao F and Xiao SD (2003) The role of nuclear factor kappa B in secretion of interleukin-8 by gastric cancer cell line SGC 7901 induced by helicobacter pylori [Article in Chinese]. Zhonghua Yi Xue Za Zhi 83 133-136 Shi W, Li L, Shi X, Zheng F, Zeng J, Jiang X, Gong F, Zhou M and Li Z (2006) Inhibition of nuclear factor-kB activation is essential for membrane-associated TNF-alpha-induced apoptosis in HL-60 cells. |
