References


 

Relevant publications listed by the last name of the first author.

[A]  [B]  [C]  [D]  [E]  [F]  [G]  [H]  [I]  [J]  [K]  [L]  [M]  [N] 
[O]  [P]  [Q]  [R]  [S]  [T]  [U]  [V]  [W]  [X]  [Y]  [Z] 


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Na HJ, Jeong HJ, Shin HY, Kim NS, Um JY, Hong SH and Kim HM (2005) Sopoongsan inhibits mast cell-mediated anaphylactic reactions and inflammatory cytokine secretion. International Archives of Allergy and Immunology 139 31-37

Na HJ, Lee SJ, Kang YC, Cho YL, Nam WD, Kim PK, Ha KS, Chung HT, Lee H, Kwon YG, Koh JS and Kim YM (2004) Inhibition of farnesyltransferase prevents collagen-induced arthritis by down-regulation of inflammatory gene expression through suppression of p21(ras)-dependent NF-kB activation. Journal of Immunology 173 1276-1283

Na HJ, Lee G, Oh HY, Jeon KS, Kwon HJ, Ha KS, Lee H, Kwon YG and Kim YM (2006) 4-O-methylgallic acid suppresses inflammation-associated gene expression by inhibition of redox-based NF-kB activation. Int
ernational Immunopharmacology 6 1597-1608

 

Na HJ, Moon PD, Ko SG, Lee HJ, Jung HA, Hong SH, Seo Y, Oh JM, Lee BH, Choi BW and Kim HM (2005) Sargassum hemiphyllum inhibits atopic allergic reaction via the regulation of inflammatory mediators. Journal of Pharmacologoical Sciences 97 219-226

Na HK, Mossanda KS, Lee JY and Surh YJ (2004) Inhibition of phorbol ester-induced COX-2 expression by some edible African plants. Biofactors 21 149-153

Na HK and Surh YJ (2003) Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands as bifunctional regulators of cell proliferation. Biochemical Pharmacology 66 1381-1391

Na HK and Surh YJ (2006) Intracellular signaling network as a prime chemopreventive target of (-)-epigallocatechin gallate.
Mol
ecular Nutrition & Food Research 50 152-159

 

Na HK and Surh YJ (2006) Transcriptional regulation via cysteine thiol modification: A novel molecular strategy for chemoprevention and cytoprotection. Molecular Carcinogenesis in press

Na HK and Surh YJ (2008) The antitumor ether lipid edelfosine (ET-18-O-CH3) induces apoptosis in H-ras transformed human breast epithelial cells: by blocking ERK1/2 and p38 mitogen-activated protein kinases as potential targets. Asia Pacific Journal of Clinical Nutrition 17 S204-S217

 

Na SI, Lee mY, Heo JS and Han HJ (20070 Hydrogen peroxide increases [3H]-2-deoxyglucose uptake via MAPKs, cPLA(2), and NF-kB signaling pathways in mouse embryonic stem cells. Cell Physiology and Biochemistry 20 1007-1018

 

Na SY, Kang BY, Chung SW, Han SJ, Ma X, Trinchieri G, Im SY, Lee JW and Kim TS (1999) Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkB. Journal of Biological Chemistry 274 7674-7680

Na S-Y, Kim H-J, Lee S-K, Choi H-S, Na D-S, Lee M-I, Chung M, Moore DD and Lee JW (1998) IkBb interacts with the retinoid X receptor and inhibits retinoid-dependent transactivation in lipopolysaccharide-treated cells. Journal of Biological Chemistry 273 3212-3215

Na S-Y, Lee S-K, Han S-J, Choi H-S, Im S-Y and Lee JW (1998) Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kB-mediated transactivations. Journal of Biological Chemistry 273 10831-10834

Na YJ, Han SB, Kang JS, Yoon YD, Park SK, Kim HM, Yang KH and Joe CO (2004) Lactoferrin works as a new LPS-binding protein in inflammatory activation of macrophages. International Immunopharmacology 4 1187-1199

Na YJ, Jeon YJ, Suh JH, Kang JS, Yang KH and Kim HM (2001) Suppression of IL-8 gene expression by radicicol is mediated through the inhibition of ERK1/2 and p38 signaling and negative regulation of NF-kB and AP-1. International Immunopharmacology 1 1877-1887

Naamane N, van Helden J and Eizirik DL (2007) In silico identification of NF-kB-regulated genes in pancreatic beta-cells. BMC Bioinformatics 8 55

Nabel G and Baltimore D (1987) An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326 711-713 

Nabel GJ (1991) HIV. Tampering with transcription. Nature 350 658

Nabel GJ and Verma IM (1993) Proposed NF-kB/IkB family nomenclature. Genes & Development 7 2063

Nadeau S and Rivest S (2000) Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and nuclear factor kB activity in the brain during endotoxemia. Journal of Neuroscience 20 3456-3468

Nadeau S and Rivest S (2002) Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: role of glucocorticoids and CD14. Journal of Immunology 169 3370-3381

Nadege A, Diane A, Saadia KR, Fanny B, Francoise R and Marc P (2007) NF-kB plays a major role in the maturation of human dendritic cells induced by NiSO4 but not by DNCB. Toxicol
ogical Sciences in press

Naderi A, Teschendorff AE, Beigel J, Cariati M, Ellis IO, Brenton JD and Caldas C (2007) BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kB inhibition of apoptosis in breast cancer cell lines. Cancer Research 67 6725-6736

Nadiminty N, Chun JY, Hu Y, Dutt S, Lin X and Gao AC (2007) LIGHT, a member of the TNF superfamily, activates Stat3 mediated by NIK pathway. Biochemical and Biophysical Research Communications 359 379-384

Nadiminty N, Lou W, Lee SO, Lin X, Trump DL and Gao AC (2006) Stat3 activation of NF-kB p100 processing involves CBP/p300-mediated acetylation. Proceedings of the National Academy of Sciences USA 103 7264-7269

Nadjar A, Combe C, Laye S, Tridon V, Dantzer R, Amedee T and Parnet P (2003) Nuclear factor kappaB nuclear translocation as a crucial marker of brain response to interleukin-1. A study in rat and interleukin-1 type I deficient mouse. Journal of Neurochemistry 87 1024-1036

Nadra I, Boccaccini AR, Philippidis P, Whelan LC, McCarthy GM, Haskard DO and Landis RC (2007) Effect of particle size on hydroxyapatite crystal-induced tumor necrosis factor alpha secretion by macrophages. Atherosclerosis
in press

Nagabhushan M, Mathews HL and Witek-Janusek L (2001) Aberrant nuclear expression of AP-1 and NFkB in lymphocytes of women stressed by the experience of breast biopsy. Brain Behav Immun 15 78-84 

Nagai N, Izumi-Nagai K, Oike Y, Koto T, Satofuka S, Ozawa Y, Yamashiro K, Inoue M, Tsubota K, Umezawa K and Ishida S (2007) Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kB pathway. Investigative Ophthalmology & Visual Science 48 4342-4350

Nagai R, Suzuki T, Aizawa K, Shindo T and Manabe I (2005) Significance of the transcription factor KLF5 in cardiovascular remodeling. Journal of Thrombosis and Haemostosis 3 1569-1576

Nagai S, Kurimoto M, Washiyama K, Hirashima Y, Kumanishi T and Endo S (2005) Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines. Journal of Neurooncology 74 105-111

Nagai S, Washiyama K, Kurimoto M, Takaku A, Endo S and Kumanishi T (2002) Aberrant nuclear factor-kB activity and its participation in the growth of human malignant astrocytoma. Journal of Neurosurgery 96 909-917

Nagaki M, Naiki T, Brenner DA, Osawa Y, Imose M, Hayashi H, Banno Y, Nakashima S and Moriwaki H (2000) Tumor necrosis factor alpha prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: role of nuclear factor-kB. Hepatology 32 1272 1279 

Nagaki M, Sugiyama A, Osawa Y, Naiki T, Nakashima S, Nozawa Y and Moriwaki H (1999) Lethal hepatic apoptosis mediated by tumor necrosis factor receptor, unlike Fas-mediated apoptosis, requires hepatocyte sensitization in mice. Journal of Hepatology 31 997-1005 

Nagamatsu Y, Nishida M, Onohara N, Fukutomi M, Maruyama Y, Kobayashi H, Sato Y and Kurose H (2006) Heterotrimeric G protein Ga(13)-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts. J
ournal of Pharmacological Sciences 101 144-150

Nagamine M, Takahara M, Kishibe K, Nagato T, Ishii H, Bandoh N, Ogino T and Harabuchi Y (2006) Sequence variations of Epstein-Barr virus LMP1 gene in nasal NK/T-cell lymphoma. Virus Genes in press

Nagamori I, Yabuta N, Fujii T, Tanaka H, Yomogida K, Nishimune Y and Nojima H (2005) Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway. Genes Cells 10 575-594

Nagao K and Yanagita T (2007) Bioactive lipids in metabolic syndrome. Progress in Lipid Research in press

Nagaoka I, Yomogida S, Tamura H and Hirata M (2004) Antibacterial cathelicidin peptide CAP11 inhibits the lipopolysaccharide (LPS)-induced suppression of neutrophil apoptosis by blocking the binding of LPS to target cells. Inflammation Research 53 609-622

Nagaruju K (2005) Role of major histocompatibility complex class I molecules in autoimmune myositis. Current Opinion in Rheumatology 17 725-730

Nagaoka K, Takahara K, Tanaka K, Yoshida H, Steinman RM, Saitoh SI, Akashi-Takamura S, Miyake K, Kang YS, Park CG and Inaba K (2005) Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria. International Immunology 17 827-836

Nagaosa K, Aikoshi I, Hasegawa Y and Nakanishi Y (2007) Activator protein 1-mediated expression of monocyte chemoattractant protein 1 in cultured rat luteal cells. Molecular and Reproductive Development inp ress

Nagaraju K, Casciola-Rosen L, Lundberg I, Rawat R, Cutting S, Thapliyal R, Chang J, Dwivedi S, Mitsak M, Chen YW, Plotz P, Rosen A, Hoffman E and Raben N (2005) Activation of the endoplasmic reticulum stress response in autoimmune myositis: Potential role in muscle fiber damage and dysfunction. Arthritis and Rheumatism 52 1824-1835

Nagasaka R, Chotimarkorn C, Shafiqul IM, Hori M, Ozaki H and Ushio H (2007) Anti-inflammatory effects of hydroxycinnamic acid derivatives. Biochemical and Biophysical Research Communications 3358 615-619

Nagasaki K, Schem C, Von Kaisenberg C, Biallek M, Rosel F, Jonat W and Maass N (2003) Leucine-zipper protein, LDOC1, inhibits NF-kB activation and sensitizes pancreatic cancer cells to apoptosis. International Journal of Cancer 105 454-458

Nagashima K, Sasseville VG, Wen D, Bielecki A, Yang H, Simpson C, Grant E, Hepperle M, Harriman G, Jaffee B, Ocain T, Xu Y and Fraser CC (2006) Rapid TNFR1 dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta.
Blood
107 4266-4273

Nagashima R, Sugiyama C, Yoneyama M, Kuramoto N, Kawada K and Ogita K (2007) Acoustic overstimulation facilitates the expression of glutamate-cysteine ligase catalytic subunit probably through enhanced DNA binding of activator protein-1 and/or NF-kB in the murine cochlea. Neurochemistry International 51 209-215

Nagata D, Suzuki E, Nishimatsu H, Satonaka H, Goto A, Omata M and Hirata Y (2001) Transcriptional activation of the cyclin D1 gene is mediated by multiple cis-elements, including SP1 sites and a cAMP-responsive element in vascular endothelial cells. Journal of Biological Chemistry 276 662-669 

Nagata K, Suzuki H and Sakaguchi S (2007) Common pathogenic mechanism in development progression of liver injury caused by non-alcoholic or alcoholic steatohepatitis. Journal of Toxicological Science 32 453-468

Nagata T, Onodera H, Ohuchi M, Suzuki Y, Tago H, Fujihara K, Ishii N, Sugamura K, Shoji Y, Handa M, Tabayashi K and Itoyama Y (2001) Decreased expression of c-myc family genes in thymuses from myasthenia gravis patients. Journal of Neuroimmunology 115 199-202 

Nagaya T, Fujieda M, Otsuka G, Yang JP, Okamoto T, Seo H (2000) A potential role of activated NF-kB in the pathogenesis of euthyroid sick syndrome. Journal of Clinical Investigation 106 393-402

Nagel T, Resnick N, Dewey CF, Jr and Gimbrone MA, Jr. (1999) Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors. Arteriosclerosis, Thrombosis and Vascular Biology 19 1825-1834 

Naghavi MH, Schwartz S, Sonnerborg A and Vahlne A (1999) Long terminal repeat promoter/enhancer activity of different subtypes of HIV type 1. AIDS Research and Human Retroviruses 15 1293-1303 

Nagy I, Caelers A, Monge A, Bonabi S, Huber AM and Bodmer D (2007) NF-kB-dependent apoptotic hair cell death in the auditory system. Audiol
ogy & Neuro-otology 12 209-222

Nagineni CN, Samuel W, Nagineni S, Pardhasaradhi K, Wiggert B, Detrick B and Hooks JJ (2003) Transforming growth factor-beta induces expression of vascular endothelial growth factor in human retinal pigment epithelial cells: Involvement of mitogen-activated protein kinases. Journal of Cell Physiology 197 453-462

Nagoshi Y, Kuwasako K, Cao YN, Imamura T, Kitamura K and Eto T (2004) Tumor necrosis factor-alpha downregulates adrenomedullin receptors in human coronary artery smooth muscle cells. Peptides 25 1115-1121

Nagy I, MOnge A, Albinger-Hegyi A< Schmid S and Bodmer D (2005) NF-kB is required for survival of immature auditory hair cells in vitro. J Assoc Res Otolaryngol 28 1-9

Nagy K, Szekely-Szuts K, Izeradjene K, Douglas L, Tillman M, Barti-Juhasz H, Dominici M, Spano C Luca Cervo G, COnte P, Houghton JA, Mihalik R, Kopper L and Petak I (2006) Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria. Pathology Oncology Research 12 133-142

Nagy LE (2004) Molecular aspects of alcohol metabolism: transcription factors involved in early ethanol-induced liver injury. Annual Reviews of Nutrition 24 55-78

Nagy M, Balazs M, Adam Z, Petko Z, Timar B, Szereday Z, Laszlo T, Warnke RA and Matolcsy A (2000) Genetic instability is associated with histological transformation of follicle center lymphoma. Leukemia 14 2142-2148

Nagy ZS, Rui H, Stepkowski SM, Karras J and Kirken RA (2006) A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor. J
ournal of Immunol
ogy 177 5032-5040

Nah SS, Choi IY, Lee CK, Oh JS, Kim YG, Moon HB and Yoo B (2008) Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes. Rheumatology in press

Nah SS, Choi IY, Yoo B, Kim YG, Moon HB and Lee CK (2007) Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-a in human osteoarthritic chondrocytes. FEBS Letters 581 1928-1932

Nah SS, Ha E, Mun SH, WOn HJ and Chung JH (2008) Effects of melittin on the production of matrix metalloproteinase-1 and -3 in rheumatoid arthritic fibroblast-like synoviocytes. Journal of Pharmacological Sciences 106 162-166

Naidu A, Dechow PC, Spears R, Wright JM, Kessler HP and Opperman LA (2008) The effects of bisphosphonates on osteoblasts in vitro. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodology in press

Naidu BV, Krishnadasan B, Byrne K, Farr AL, Rosengart M, Verrier ED and Mulligan MS (2002) Regulation of chemokine expression by cyclosporine A in alveolar macrophages exposed to hypoxia and reoxygenation. Annals of Thoracic Surgery 74 899-905

Naidu BV, Krishnadasan B, Farivar AS, Woolley SM, Thomas R, Van Rooijen N, Verrier ED and Mulligan MS (2003) Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury. Journal of Thoracic and Cardiovascular Surgery 126 200-207

Naik S, Kelly EJ, Meijer L, Pettersson S and Sanderson IR (2001) Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium. Journal of Pediatric Gastroenterology and Nutrition 32 449-453

Nair A, Venkatraman M, Maliekal TT, Nair B, Karunagaran D (2003) NF-kB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix. Oncogene 22 50-58

Nair AS, Shishodia S, Ahn KS, Kunnumakkara AB, Sethi G and Aggarwal BB (2006) Deguelin, an Akt inhibitor, suppresses IkBa kinase activation leading to suppression of NF-kB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. J
ournal of Immunology 177 5612-5622

Nair PK, Melnick SJ, Ramachandran R, Escalon E and Ramachandran C (2006) Mechanism of macrophage activation by (1,4)-alpha-d-glucan isolated from Tinospora cordifolia. International Immunopharmacology 6 1815-1824

Nair S, Li W and Kong AN (2007) Natural dietary anti-cancer chemopreventive compounds: redox-mediated differential signaling mechanisms in cytoprotection of normal cells versus cytotoxicity in tumor cells. Acta Pharmacologica Sinica 28 459-472

Naisbitt DJ, Hough SJ, Gill HJ, Pirmohamed M, Kitteringham NR and Park BK (1999) Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity. British Journal of Pharmacology 126 1393-1407 

Naito Y, Handa O, Takagi T, Ishikawa T, Imamoto E, Nakagawa S, Yamaguchi T, Yoshida N, Matsui H and Yoshikawa T (2002) Ubiquitin-proteasome inhibitor enhances tumour necrosis factor-alpha- induced apoptosis in rat gastric epithelial cells. Aliment Pharmacol Ther 16 59-66  

Naito Y, Takagi T, Handa O, Ishikawa T, Nakagawa S, Yamaguchi T, Yoshida N, Minami M, Kita M, Imanishi J and Yoshikawa T (2003) Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. Journal of Gastroenterology and Hepatology 18 560-569

Naito Y, Takagi T, Ishikawa T, Handa O, Matsumoto N, Yagi N, Matsuyama K,
Yoshida N, Yoshikawa T and Kotake Y (2002) alpha-Phenyl-N-tert-butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice. Antioxidant and Redox Signaling 4 195-206  

 

Najjar I, Baran-Marszak F, Le Clorennec C, Laguillier C, Schischmanoff O, Youlyouz-Marfak I, Schlee M, Bornkamm GW, Raphael M, Feuillard J and Fagard R (2005) Latent membrane protein 1 regulates STAT1 through NF-kB-dependent interferon secretion in Epstein-Barr Virus-immortalized B cells. Journal of Virology 79 4936-4943


Nakabe N, Kokura S, Shimozawa M, Katada K, Sakamoto N, Ishikawa T, Handa O, Takagi T, Naito Y, Yoshida N and Yoshikawa T (2007) Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in human arterial endothelial cells. Int
ernational Journal of Hyperthermia 23 217-224

 

Nakagami H, Tomita N, Kaneda Y, Ogihara T and Morishita R (2006) Anti-oxidant gene therapy by NFkB decoy oligodeoxynucleotide. Current Pharmaceutical Biotechnology 7 95-100

 

Nakagawa M, Hosokawa Y, Yonezumi M, Izumiyama K, Suzuki R, Tsuzuki S, Asaka M and Seto M (2005) MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10. Blood 106 4210-4216

Nakagawa M, Seto M and Hosokawa Y (2006) Molecular pathogenesis of MALT lymphoma: two signaling pathways underlying the antiapoptotic effect of API2-MALT1 fusion protein. Leukemi
a 20 929-936

 

Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Yano K, Morinaga T and Higashio K (1998) RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochemical and Biophysical Research Communications 253 395-400 

Nakagawa R, Naka T, Tsutsui H, Fujimoto M, Kimura A, Abe T, Seki E, Sato S, Takeuchi O, Takeda K, Akira S, Yamanishi K, Kawase I, Nakanishi K and Kishimoto T (2002) SOCS-1 participates in negative regulation of LPS responses. Immunity 17 677-687

Nakagawa S, Kushiya K, Taneike I, Imanishi K, Uchiyama T and Yamamoto T (2005) Specific inhibitory action of anisodamine against a Staphylococcal superantigenic toxin, toxic shock syndrome toxin 1 (TSST-1), leading to down-regulation of cytokine production and blocking of TSST-1 toxicity in mice. Clinical Diagnosis and Laboratory Immunology 12 399-408

Nakagawa T and Yamaguchi M (2007) Overexpression of regucalcin suppresses cell response for tumor necrosis factor-alpha or transforming growth factor-beta1 in cloned normal rat kidney proximal tubular epithelial NRK52E cells. Journal of Cellular Biochemistry 100 1178-1190

Nakagawa Y and Akao Y (2006) Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kB in colon cancer cell lines. Experimental Cell Research 312 2433-2442

Nakagawa Y, Iinuma M, Matsuura N, Yi K, Naoi M, Nakayama T, Nozawa Y and Akao Y (2005) A potent apoptosis-inducing activity of a sesquiterpene lactone, arucanolide, in HL60 cells: a crucial role of apoptosis-inducing factor. Journal of Pharmacological Sciences 97 242-252

Nakahara C, Nakamura K, Yamanaka N, Baba E, Wada M, Matsunaga H, Noshiro H, Tanaka M, Morisaki T and Katano M (2003) Cyclosporin-A enhances docetaxel-induced apoptosis through inhibition of nuclear factor-kB activation in human gastric carcinoma cells. Clinical Cancer Research 9 5409-5416

Nakahara H, Gabazza EC, Fujimoto H, Nishii Y, D'Alessandro-Gabazza CN, Bruno NE, Takagi T, Hayashi T, Maruyama J, Maruyama K, Imanakaa-Yoshida K, Suzuki K, Yoshida T, Adachi Y and Taguchi O (2006) Deficiency of tenascin C attenuates allergen-induced bronchial asthma in the mouse.
Eur
opean Journal of Immunology 36 3334-3345

Nakahara S, Tsunoda T, Baba T, Asabe S, Tahara H (2003) Dendritic cells stimulated with a bacterial product, OK-432, efficiently induce cytotoxic T lymphocytes specific to tumor rejection peptide. Cancer Research 63 4112-4118

Nakahira K, Takahashi T, Shimizu H, Maeshima K, Uehara K, Fujii H, Nakatsuka H, Yokoyama M, Akagi R and Morita K (2003) Protective role of heme oxygenase-1 induction in carbon tetrachloride-induced hepatotoxicity. Biochemical Pharmacology 66 1091-1105

Nakahira M, Tomura M, Iwasaki M, Ahn HJ, Bian Y, Hamaoka T, Ohta T, Kurimoto M and Fujiwara H (2001) An absolute requirement for STAT4 and a role for IFN-g as an amplifying factor in IL-12 induction of the functional IL-18 receptor complex. Journal of Immunology 167 1306-1312

Nakai K, Kubota Y and Kosaka H (2004) Inhibition of nuclear factor kB activation and inducible nitric oxide synthase transcription by prolonged exposure to high glucose in the human keratinocyte cell line HaCaT. British Journal of Dermatology 150 640-646

Nakai M, Qin Z, Wang Y and Chase TN (2000) NMDA and non-NMDA receptor-stimulated IkB-a degradation: differential effects of the caspase-3 inhibitor DEVD.CHO, ethanol and free radical scavenger OPC-14117. Brain Research 859 207-216

Nakai M, Qin ZH, Chen JF, Wang Y and Chase TN (2000) Kainic acid-induced apoptosis in rat striatum is associated with nuclear factor-kappaB activation. Journal of Neurochemsitry 74 647-658

Nakai M, Qin ZH, Wang Y and Chase TN (1999) Free radical scavenger OPC-14117 attenuates quinolinic acid-induced NF-kB activation and apoptosis in rat striatum. Brain Research Molecular Brain Research 64 59-68 

Nakai M, Sudo K, Yamada Y, Kojima Y, Kato T, Saito K, Moriwaki H and Seishima M (2005) The role of the tumor necrosis factor receptor in 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in mice. Dig Dis Sci 50 1669-1676

Nakajima A, Kojima Y, Nakayama M, Yagita H, Okumura K and Nakano H (2007) Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells. Oncogene in press

Nakajima A, Komazawa-Sakon S, Takekawa M, Sasazuki T, Yeh WC, Yagita H, Okumura K and Nakano H (2006) An antiapoptotic protein, c-FLIP(L), directly binds to MKK7 and inhibits the JNK pathway. EMBO Journal 25 5549-5559

Nakajima A, Wada K, Miki H, Kubota N, Nakajima N, Terauchi Y, Ohnishi S, Saubermann LJ, Kadowaki T, Blumberg RS, Nagai R and Matsuhashi N (2001) Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury. Gastroenterology 120 460-469 

Nakajima H, Fujiwara H, Furuichi Y, Tanaka K and Shimbara N (2008) A novel small-molecule inhibitor of NF-kB signaling. Biochemical and Biophysical Research Communications in press

Nakajima H, Nagaso H, Kakui N, Ishikawa M, Hiranuma T and Hoshiko S (2004) Critical role of the auto-modification of poly(ADP-ribose) polymerase-1 in the nuclear factor-kB-dependent gene expression in primary cultured mouse glial cells. Journal of Biological Chemistry 279 42774-42786

Nakajima K, Honda S, Nakamura Y, Lopez-Redondo F, Kohsaka S, Yamato M, Kikuchi A and Okano T (2001) Intact microglia are cultured and non-invasively harvested without pathological activation using a novel cultured cell recovery method. Biomaterials 22 1213-1223

Nakajima K, Kikuchi Y, Ikoma E, Honda S, Ishikawa M, Liu Y and Kohsaka S (1998) Neurotrophins regulate the function of cultured microglia. Glia 24 272-289

Nakajima T, Kitajima I, Shin H, Takasaki I, Sigeta K, Abeyama K, Yamashita Y, Tokioka T, Soejima T and Maruyama I (1994) Involvement of NF-kB activation in thrombin-induced human vascular smooth muscle cell proliferation. Biochemical and Biophysical Research Communications 204 950-955

Nakajima Y, Furuichi Y, Biswas KK, Hashiguchi T, Kawahara KI, Yamaji K, Uchimura T, Izumi Y and Maruyama I (2006) Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kB pathway inhibition.
FEBS Lett
ers 580 613-619

Nakamichi K, Saiki M, Kitani H, Kuboyama Y, Morimoto K, Takyama-Ito M and Kurane I (2007) Roles of NF-kB and MAPK signaling pathways in morphological and cytoskeletal responses of microglia to double-stranded RNA. Neuroscience Letters 414 222-227

Nakamichi K, Saiki M, Sawada M, Takayama-Ito M, Yamamuro Y, Morimoto K and Kurane I (2005) Rabies virus-induced activation of mitogen-activated protein kinase and NF-kB signaling pathways regulates expression of CXC and CC chemokine ligands in microglia. Journal of Virology 79 11801-11812

Nakamichi K, Saiki M, Sawada M, Yamamuro T, Morimoto K and Kurane I (2005) Double-stranded RNA stimulates chemokine expression in microglia through vacuolar pH-dependent activation of intracellular signaling pathways. Journal of Neurochemistry 95 273-283

Nakamori Y, Koh T, Ogura H, Tanaka H, Fujimi S, Kasai K, Hosotubo H, Shimazu T and Sugimoto H (2003) Enhanced expression of intranuclear NF-kB in primed polymorphonuclear leukocytes in systemic inflammatory response syndrome patients. Journal of Trauma 54 253-260

Nakamori Y, Ogura H, Koh T, Fujita K, Tanaka H, Sumi Y, Hosotsubo H, Yoshiya K, Irisawa T, Kuwagata Y, Shimazu T and Sugimoto H (2005) The balance between expression of intranuclear NF-kB and glucocorticoid receptor in polymorphonuclear leukocytes in SIRS patients. Journal of Trauma 59 308-315

Nakamura A, Johns EJ, Imaizumi A, Yanagawa Y and Kohsaka T (2001) Activation of beta(2)-adrenoceptor prevents shiga toxin 2-induced TNF-alpha gene transcription. Journal of the American Society of Nephrology 12 2288-2299

Nakamura H, Aoki M, Tamai K, Oishi M, Ogihara T, Kaneda Y and Morishita R (2002) Prevention and regression of atopic dermatitis by ointment containing NF-kB decoy oligodeoxynucleotides in NC/Nga atopic mouse model. Gene Therapy 9 1221-1229

Nakamura H, Fukusaki T, Toshimura A, Shiraishi C, Kishimoto M, Kaneko T and Hara Y (2008) Lack of Toll-like receptor 4 decreases lipopolysaccharide-induced bone resorption in C3H/HeJ mice in vivo. Oral Microbiology and Immunology 23 190-195

Nakamura H, Kawakami A, Ida H, Koji T and Eguchi K (2007) EGF activates PI3K-Akt and NF-kB via distinct pathways in salivary epithelial cells in Sjogren's syndrome. Rheumatology International in press

Nakamura H, Ishii C, Suehiro M, Iguchi A, Kuroda K, Shimizu K, Shimizu N, Imadome KI, Yajima M and Fujiwara S (2007) The latent membrane protein 1 (LMP1) encoded by Epstein-Barr virus induces expression of the putative oncogene Bcl-3 through activation of the nuclear factor-kappaB. Virus Research in press

Nakamura H, Kimura T, Ogita K, Nakamura T, Takemura M, Shimoya K, Koyama S, Tsujie T, Koyama M and Murata Y (2004) NF-kB activation at implantation window of the mouse uterus. American Journal of Reproductive Immunology 51 16-21

Nakamura H, Kimura T, Ogita K, Koyama S, Tsujie T, Tsutsui T, Shimoya K, Koyama M, Kaneda Y and Murata Y (2004) Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kB activity and partial rescue by leukemia inhibitory factor. Biochemical and Biophysical Research Communications 321 886-892

Nakamura H, Masutani H and Yodoi J (2002) Redox imbalance and its control in HIV infection. Antioxid Redox Signal 4 455-464

Nakamura J, Shibata K, Hasebe A, Into T, Watanabe T and Ohata N (2002) Signaling pathways induced by lipoproteins derived from Mycoplasma salivarium and a synthetic lipopeptide (FSL-1) in normal human gingival fibroblasts. Microbiol Immunol 46 151-158

Nakamura K, Miyazato A, Koguchi Y, Adachi Y, Ohno N, Saijo S, Iwakura Y, Takeda K, Akira S, Fujita J, Ishii K, Kaku M and Kawakami K (2008) Toll-like receptor 2 (TLR2) and dectin-1 contribute to the production of IL-12p40 by bone marrow-derived dendritic cells infected with Penicillium marneffei. Microbes and Infection in press

Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, Shiratori K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Suzuki K, Fujita J, Kaku M and Kawakami K (2008) Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway. Journal of Immunology 180 4067-4074

Nakamura K, Senda T, Sato K, Mori S and Moriyma M (2005) Accumulation of BCL10 at the perinuclear region is required for the BCL10-mediated nuclear factor-kB activation. Pathobiology 72 191-202

Nakamura K, Yasunaga Y, Segawa T, Ko D, Moul JW, Srivastava S and Rhim JS (2002) Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines. International Journal of Oncology 21 825-830

Nakamura N, Hayasaka S, Zhang XY, Nagaki Y, Matsumoto M, Hayasaka Y and Terasawa K (2003) Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line. Experimental Eye Research 77 195-202

Nakamura N, Shimaoka Y, Tougan T, Onda H, Okuzaki D, Zhao H, Fujimori A, Yabuta N, Nagamori I, Tanigawa A, Sato J, Oda T, Hayashida K, Suzuki R, Yukioka M Nojima H and Ochi T (2006) Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients. DNA Research 13 169-183

Nakamura T, Donovan DM, Hamada K, Sax CM, Norman B, Flanagan JR, Ozato K, Westphal H and Piatigorsky J (1990) Regulation of the mouse aA-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes. Molecular and Cellular Biology 10 3700-3708

Nakamura T, Goto M, Matsumoto A and Tanaka I (1998) Inhibition of NF-kB transcriptional activity by a-Tocopheryl succinate. Biofactors 7 21-30

Nakamura T, Kuwai R, Kitadai Y, Sasaki T, Fan D, Coombes KR, Kim SJ and Fidler IJ (2007) Zonal heterogeneity for gene expression in human pancreatic carcinoma. Cancer Research 67 7597-7604

Nakamura T, Ouchida R, Kodama T, Kawashima T, Makino Y, Yoshikawa N, Watanabe S, Morimoto C, Kitamura T and Tanaka H (2001) Cytokine receptor common beta subunit-mediated STAT5 activation confers NF-kB activation in murine proB cell line Ba/F3 cells. Journal of Biological Chemistry 277 6254-6265

Nakamura T, Suzuki H, Wada Y, Kodama T and Doi T (2006) Fucoidan induces nitric oxide production via p38 mitogen-activated protein kinase and NF-kappaB-dependent signaling pathways through macrophage scavenger receptors.
Biochem
ical and Biophysical Research Communications
343 286-294

Nakamura Y, Grumont RJ and Gerondakis S (2002) NF-kB1 can inhibit v-Abl-induced lymphoid transformation by functioning as a negative regulator of cyclin D1 expression. Molecular and Cellular Biology 22 5563-5574   

Nakamura Y, Grumont RJ and Gerondakis S (2002) NF-kB1 can inhibit v-Abl-induced lymphoid transformation by functioning as a negative regulator of cyclin D1 expression. Molecular and Cellular Biology 22 5563-5574

Nakamuta M, Enjoji M, Uchimura K, Ohta S, Sugimoto R, Kotoh K, Kato M, Irie T, Muta T and Nawata H (2002) Bisphenol a diblycidyl ether (badge) suppresses tumor necrosis factor-a production as a PPARg agonist in the murine macrophage-like cell line, RAW.264.7. Cell Biology International 26 235-241  

Nakamuta M, Ohta S, Tada S, Tsuruta S, Sugimoto R, Kotoh K, Kato M, Nakashima Y, Enjoji M and Nawata H (2001) Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats. International Journal of Molecular Medicine 8 553-560

Nakane M, Ichikawa S and Matsuda A (2008) Triazole-linked dumbbell oligodeoxynucleotides with NF-kB binding ability as potential decoy molecules. Journal of Organic Chemistry in press

Nakanishi C and Toi M (2005) Nuclear factor-kB inhibitors as sensitizers to anticancer drugs. Nature Reviews Cancer 5 297-309

Nakanishi H, Kaibori M, Teshima S, Yoshida H, Kwon AH, Kamiyama Y, Nishizawa M, Ito S and Okumura T (2004) Pirfenidone inhibits the induction of iNOS stimulated by interleukin-1beta at a step of NF-kB DNA binding in hepatocytes. Journal of Hepatology 41 730-736

Nakano H (2004) Signaling crosstalk between NF-kB and JNK. Trends in Immunology 25 402-405

Nakano H (2005) Signaling crosstalk between NF-kappaB and JNK [Article in Japanese]. Seikagaku 77 29-32

Nakano H, Nakajima A, Sakon-Komazawa S, Piao JH, Xue X and Okumura K (2006) Reactive oxygen species mediate crosstalk between NF-kB and JNK. Cell Death & Differentiation 13 730-737

Nakano H, Sakon S, Koseki H, Takemori T, Tada K, Matsumoto M, Munechika E, Sakai T, Shirasawa T, Akiba H, Kobata T, Santee SM, Ware CF, Rennert PD, Taniguchi M, Yagita H and Okumura K (1999) Targeted disruption of TRAF5 gene causes defects in CD40- and CD27-mediated lymphocyte activation. Proceedings of the National Academy of Sciences USA 96 9803-9808 

Nakano H, Shindo M, Sakon S, Nishinaka S, Mihara M, Yagita H and Okumura K (1998) Differential regulation of IkB kinase a and b by two upstream kinases, NF-kB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase 1. Proceedings of the National Academy of Sciences USA 95 3537-3542

Nakano M, Tsuboi T, Kato M, Kurita K, Togari A (2003) Inhibitory effect of titanium particles on osteoclast formation generated by treatment of mouse bone marrow cells with PGE2. Oral Disease 9 77-83

Nakao A, Kaczorowski DJ, Zuckerbraun BS, Lei J, Faleo G, Deguchi K, McCurry KR, Billiar TR and Kanno S (2007) Galantamine and carbon monoxide protect brain microvascular endothelial cells by heme oxygenase-1 induction. Biochemical and Biophysical Research Communications in press

Nakao A, Otterbein LE, Overhaus M, Sarady JK, Tsung A, Kimizuka K, Nalesnik MA, Kaizu T, Uchiyama T, Liu F, Murase N, Bauer AJ and Bach FH (2004) Biliverdin protects the functional integrity of a transplanted syngeneic small bowel. Gastroenterology 127 595-606

Nakao A, Schmidt J, Harada T, Tsung A, Stoffels B, Cruz Jr RJ, Kohmoto J, Peng X, Tomiyama K, Murase N, Bauer AJ and Fink MP (2006) A single intraperitoneal dose of carbon monoxide-saturated Ringer's lactate solution ameliorates post-operative ileus in mice. J
ournal of Pharmacology and Experimental Therapeutics
319 1265-1275

Nakao N, Kurokawa T, Nonami T, Tumurkhuu G, Koide N and Yokochi T (2008) Hydrogen peroxide induces the production of tumor necrosis factor-a in RAW 264.7 macrophage cells via activation of p38 and stress-activated protein kinase. Innate Immunity 14 190-196

Nakao S, Hata Y, Miura M, Noda K, Kimura YN, Kawahara S, Kita T, Hisatomi T, Nakazawa T, Kim Y, Dana MR, Kuwano M, Ono M, Ishibashi T and Hafezi-Moghadam A (2007) Dexamethasone inhibits interleukin-1beta-induced corneal neovascularization. Role of nuclear factor-kB-activated stromal cells in inflammatory angiogenesis. American Journal of Pathology in press

Nakao S, Ogtata Y, Shimizu E, Yamazaki M, Furuyama S and Sugiya H (2002) Tumor necrosis factor alpha (TNF-alpha)-induced prostaglandin E2 release is mediated by the activation of cyclooxygenase-2 (COX-2) transcription via NFkB in human gingival fibroblasts. Molecular and Cellular Biochemistry 238 11-18

Nakao Y, Funami K, Kikkawa S, Taniguchi M, Nishiguchi M, Fukumori Y, Seya T and Matsumoto M (2005) Surface-expressed TLR6 participates in the recognition of diacylated lipopeptide and peptidoglycan in human cells. Journal of Immunology 174 1566-1573

Nakase H, Okazaki K, Tabata Y, Uose S, Ohana M, Uchida K, Nishi T, Debreceni A, Itoh T, Kawanami C, Iwano M, Ikada Y and Chiba T (2001) An oral drug delivery system targeting immune-regulating cells ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis. Journal of Pharmacology and Experimental Therapy 297 1122-1128

Nakashima H, Aoki M, Miyake T, Kawasaki T, Iwai M, Jo N, Oishi M, Kataoka K, Ohgi S, Ogihara T, Kaneda Y and Morishita R (2003) Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of Nuclear Factor kB and Ets transcription factors. Circulation 109 132-138

Nakashima H,Nakamura M, Yamaguchi H, Yamanaka N, Akiyoshi T,Koga K, Yamaguchi K, Tsuneyoshi M, Tanaka M and Katano M (2006) Nuclear factor-kB contributes to Hedgehog signaling pathway activation through Sonic Hedgehog induction in pancreatic cancer. Cancer Res
earch 66 7041-7049

Nakashima I, Liu W, Akhand AA, Takeda K, Kawamoto Y, Kato M and Suzuki H (2003) 4-Hydroxynonenal triggers multistep signal transduction cascades for suppression of cellular functions. Molecular Aspects of Medicine 24 231-238

Nakashima O, Terada Y, Inoshita S, Kuwahara M, Sasaki S and Marumo F (1999) Inducible nitric oxide synthase can be induced in the absence of active nuclear factor-kB in rat mesangial cells: involvement of the Janus kinase 2 signaling pathway. Journal of the American Society of Nephrology 10 721-729 

Nakashima Y, Sun DH, Trindade MC, Maloney WJ, Goodman SB, Schurman DJ and Smith RL (1999) Signaling pathways for tumor necrosis factor-alpha and interleukin-6 expression in human macrophages exposed to titanium-alloy particulate debris in vitro. J Bone Joint Surg Am 81 603-615

Nakata H, Uemura Y, Kobayashi M, Harada R and Taguchi H (2003) Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells. Cancer Science 94 173-180

Nakata K, Hoshino Y, Honda Y, Tanaka N, Hebisawa A and Weiden M (2004) Molecular pathogenesis in tuberculosis complicated with AIDS [Article in Japanese]. Kekkaku 79 659-667

Nakata S, Matsumura I, Tanaka H, Ezoe S, Satoh Y, Ishikawa J, Era T and Kanakura Y (2004) NF-kB family proteins participates in multiple steps of hematopoiesis through elimination of reactive oxygen species. Journal of Biological Chemistry 279 55578-55586

Nakata S, Tsutsui M, Shimokawa H, Yamashita T, Tanimoto A, Tasaki H, Ozumi K, Sabanai K, Morishita T, Suda O, Hirano H, Sasaguri Y, Nakashima Y and Yanagihara N (2007) Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/NF-kB pathway. Arterioscler
osis, Thrombosis and Vascular Biology
27 92-98

Nakata T, Yasuda M, Fujita M, Kataoka H, Kiura K, Sano H and Shibata K (2006) CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex. Cellular Microbiology in press

Nakatani K, Yamakuni T, Kondo N, Arakawa T, Oosawa K, Shimura S, Inoue H and Ohizumi Y (2004) gamma-mangostin inhibits IkB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells. Molecular Pharmacology 66 667-674

Nakatani T, Tamada S, Asai T, Iwai Y, Kim T, Tsujino T, Kumata N, Uchida J, Tashiro K, Kuwabara N, Komiya T, Sumi T, Okamura M and Miura K (2002) Role of renin-angiotensin system and nuclear factor-kB in the obstructed kidney of rats with unilateral ureteral obstruction. Japanese Journal of Pharmacology 90 361-364

Nakayama H, Ikebe T, Beppu M and Shirasuna K (2001) High expression levels of nuclear factor kB, IkB kinase alpha and Akt kinase in squamous cell carcinoma of the oral cavity. Cancer 92 3037-3044

Nakayama H, Ikebe T and Shirasuna K (2005) Effects of IkB kinase alpha on the differentiation of squamous carcinoma cells. Oral Oncology 41 729-737

Nakayama K, Hatakeyama S, Maruyama SI, Kikuchi A, Onoe K, Good RA and Nakayama KI (2003) Impaired degradation of inhibitory subunit of NF-kB (IkB) and {beta}-catenin as a result of targeted disruption of the {beta}-TrCP1 gene. Proceedings of the National Academy of Sciences USA 100 8752-8757

Nakayama K, Ota Y, Okugawa S, Ise N, Kitazawa T, Tsukada K, Kawada M, Yanagimoto S and Kimura S (2003) Raf1 plays a pivotal role in lipopolysaccharide-induced activation of dendritic cells. Biochemical and Biophysical Research Communications 308 353-360

Nakayama K, Shimizu H, Mitomo K, Watanabe T, Okamoto S-I and Yamamoto K-I (1992) A lymphoid cell-specific nuclear factor containing c-Rel-like proteins preferentially intereacts with interleukin-6 kB-related motifs whose activities are repressed in lymphoid cells. Molecular and Cellular Biology 12 1736-1746

Nakayama T, Hieshima K, Nagakubo D, Sato E, Nakayama M, Kawa K and Yoshie O (2004) Selective induction of Th2-attracting chemokines CCL17 and CCL22 in human B cells by latent membrane protein 1 of Epstein-Barr Virus. Journal of Virology 78 1665-1674

Nakayama Y, Kato N, Nakajima Y, Shimizu E and Ogata Y (2004) Effect of TNF-a on human osteosarcoma cell line Saos2-TNF-a regulation of bone sialoprotein gene expression in Saos2 osteoblast-like cells. Cell Biology International 28 653-660

Nakazawa M, Ishii H, Nakamura H, Yoshino SI, Fukamizu A, Nishioka K and Nakajima T (2001) NFkB2 (p52) promoter activation via Notch signaling pathway in rheumatoid synoviocytes. International Journal of Molecular Medicine 7 31-35 

Nakkuntold J, Wongsurawat T, Charoenwongse P, Snabboon T, Sridama V and Hirankarn N (2006) Association of TNF-alpha, TNF-beta, IFN-gamma and IL-1Ra gene polymorphisms with Graves' disease in the Thai population. Asian Pacific Journal of Allergy and Immunology 24 207-211

Nakoshi Y, Hasegawa M, Sudo A, Yoshida T and Uchida A (2007) Regulation of tenascin-C expression by tumor necrosis factor-a in cultured human osteoarthritis chondrocytes. Journal of Rheumatology in press

Nakshatri H, Bhat-Nakshatri P, Martin DA, Goulet Jr Rj and Sledge Jr GW (1997) Constitutive activation of NF-kB during progression of breast cancer to hormone-independent growth. Molecular and Cellular Biology 17 3629-3639

Nakshatri H and Goulet RJ Jr (2002) NF-kB and breast cancer. Current Problems in Cancer 26 282-309

Nakshatri H, Rice P and Bhat-Nakshatri P (2004) Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 23 7330-7344

Nakakuki T, Ito M, Iwasaki H, Kureishi Y, Okamoto R, Moriki N, Kongo M, Kato S, Yamada N, Isaka N and Nakano T (2005) Rho/Rho-kinase pathway contributes to C-reactive protein-induced plasminogen activator inhibitor-1 expression in endothelial cells. Arterioscler Thromb Vasc Biol in press

Nalca A, Q
iu SG, El-Guendy N, Krishnan S and Rangnekar VM (1999) Oncogenic Ras sensitizes cells to apoptosis by Par-4. Journal of Biological Chemistry 274 29976-29983 

Nam HY, Ahn EK, Kim HJ, Lim Y, Lee CB, Lee KY and Vallyathan V (2006) Diesel exhaust particles increase IL-1beta-induced human beta-defensin expression via NF-kB-mediated pathway in human lung epithelial cells. Part Fibre Toxicol
ogy 3 9

Nam HY, Choi BH, Lee JY, Lee SG, Kim YH, Lee KH, Yoon HK, Song JS, Kim HJ and Lim Y (2004) The role of nitric oxide in the particulate matter (PM2.5)-induced NFkB activation in lung epithelial cells. Toxicology Letters 148 95-102

Nam JS, Cho MH, Lee Gt,Park JS, Ahn CW, Cha BS, Lim SK, Kim KR, Ha HJ and Lee HC (2008) The activation of NF-kB and AP-1 in peripheral blood mononuclear cells isolated from patients with diabetic nephropathy. Diabetes Reearch and Clinical Practice in press

Nam J-S, Hirohashi S and Wakefield LM (2007) Dyadherin: a new player in cancer progression. Cancer Letters 255 161-169

Nam KH, Choi JH, Seo YJ, Lee YM, Won YS, Lee MR, Lee MN, Park JG, Kim YM, Kim HC, Lee CH, Lee HK, Oh SR and Oh ST (2006) Inhibitory effects of tilianin on the expression of inducible nitric oxide synthase in low density lipoprotein receptor deficiency mice. Experimental Molecular Medicine 38 445-452

Nam KN, Koketsu M and Lee EH (2008) 5-Chloroacetyl-2-amino-1,3-selenazoles attenuate microglial inflammatory responses through NF-kB inhibition. European Journal of Pharmacology in press

Nam KO, Kang H, Shin SM, Cho KH, Kwon B, Kwon BS, Kim SJand Lee HW (2005) Cross-linking of 4-1BB activates TCR-signaling pathways in CD8+ T lymphocytes. Journal of Immunology 174 1898-1905

Nam KW, Kim J, Hong JJ, Choi JH, Mar W, Cho MH, Kim YM, Oh SR, Lee HK, Nam KH and Oh GT (2005) Inhibition of cytokine-induced IkB kinase activation as a mechanism contributing to the anti-atherogenic activity of tilianin in hyperlipidemic mice. Atherosclerosis 180 27-35

Nam NH (2006) Naturally occurring NF-kB inhibitors. Mini Reviews in Medicinal Chemistry 6 945-951

Nam SY, Cho KS, Heo YM, Ha JC, Kim YH, Keun Yi H, Han Hwang P, Kim HM and Podack ER (2002) Regulation of lymphocyte clustering by CD30-mediated ICAM-1 up-regulation. Cell Immunol 219 38-47

Nam SY and Chung HY (2005) The suppression of radiation-induced NF-kB activity by dexamethasone correlates with increased cell death in vivo. Biochemical and Biophysical Research Communications 336 603-608

Nam SY, Kim JS, Kim JM, Lee JY, Kim N, Jung HC and Song IS (2008) DA-6034, a derivative of flavonoid, prevents and ameliorates dextran sulfate sodium-induced colitis and inhibits colon carcinogenesis. Experimental Biology and Medicine (Maywood) 233 180-191

Nam Y, Weng AP, Aster JC and Blacklow SC (2003) Structural requirements for assembly of the CSL/intracellular notch1/mastermind-like 1 transcriptional activation complex. Journal of Biological Chemistry 278 21232-21239

Namba H, Saenko V and Yamashita S (2007) Nuclear factor-kB in thyroid carcinogenesis and progression: a novel therapeutic target for advanced thyroid cancer. Arq
uivos Brasilieros de Endocrinologia et Metabologia 51 843-851

Nambiar MP, Fisher CU, Warke VG, Krishnan S, Mitchell JP, Delaney N and Tsokos GC (2003) Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus. Arthritis & Rheumatism 48 1948-1955

Nan L, Wu Y, Bardag-Gorce F, Li J, French BA, Wilson LT and French SW (2005) Experimental and Molecular Pathology 78 198-206 

Nandakumar DN, Koner BC, Vinayagamoorthi R, Nanda N, Negi VS, Goswami K, BObby Z and Hamide A (2008) Activation of NF-kB in lymphocytes and increase in serum immunoglobulin in hyperthyroidism: Possible role of oxidative stress. Immunobiology 213 409-415

Nandakumar V, Singh T and Katiyar SK (2008) Multi-targeted prevention and therapy of cancer by proanthocyanidins. Cancer Letters in press

Nanduri J and Nanduri RP (2007) Cellular mechanisms associated with intermittent hypoxia. Essays in Biochemistry 43 91-104

Nanes MS (2003) Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology. Gene 321 1-15

Nangle MR, Cotter MA and Cameron NE (2006) IkB kinase 2 inhibition corrects defective nitrergic erectile mechanisms in diabetic mouse corpus cavernosum. Urology 68 214-218

Nanji AA, Jokelainen K, Fotouhinia M, Rahemtulla A, Thomas P, Tipoe GL, Su GL and Dannenberg AJ (2001) Increased severity of alcoholic liver injury in female rats: role of oxidative stress, endotoxin, and chemokines. American Journal of Physiolpgu: Gastrointestinal and Liver Physiology 281 G1348-G1356

Nanji AA, Jokelainen K, Lau GK, Rahemtulla A, Tipoe GL, Polavarapu R and Lalani EN (2001) Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration. Journal of Pharmacology and Experimental Therapeutics 299 832-839

Nanji AA, Jokelainen K, Rahemtulla A, Miao L, Fogt F, Matsumoto H, Tahan SR and Su GL (1999) Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholic liver disease in the rat. Hepatology 30 934-943 

Nanji AA, Jokelainen K, Tipoe GL, Rahemtulla A and Dannenberg AJ (2001) Dietary saturated fatty acids reverse inflammatory and fibrotic changes in rat liver despite continued ethanol administration. Journal of Pharmacology and Experimental Therapeutics 299 638-644

Nanji AA, Jokelainen K, Tipoe GL, Rahemtulla A, Thomas
P and Dannenberg AJ (2002) Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kB-dependent genes. American Journal of Physiology: Gastrointestinal and Liver Physiology 284 G321-G327

Nanki T (2007) Molecular mechanisms of bone destruction in rheumatoid arthritis [Article in Japanese]. Clin
ical Calcium 17 510-516

Nanthakumar NN, Young C, Ko JS, Meng D, Chen J, Buie T and Walker WA (2005) Glucocorticoid responsiveness in developing human intestine: possible role in prevention of necrotizing enterocolitis. American Journal of Physiology: Gastrointestinal and Liver Physiology 288 G85-G92

Nanua S, Zick SM, Andrade JE, Burgess JR, Lukacs NW and Hershenson MB (2006) Quercetin blocks airway epithelial cell chemokine expression. Am
erican Journal of Respiratory Cell and Molecular Biology 35 602-610

Naoi M, Maruyama W, Yi H, Akao Y, Yamaoka Y and Shamoto-Nagai M (2007) Neuroprotection by propargylamines in Parkinson's disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers. Journal of Neural Transmission Supplement 121-131

Naomoto Y, Gunduz M, Takaoka M, Okawa T, Gunduz E, Nobuhisa T, Kobayashi M, Shirakawa Y, Tamatsuji T, Sonoda R, Matsuoka J and Tanaka N (2007) Heparanase promotes angiogenesis through Cox-2 and HIF1alpha. Medical Hypotheses 68 162-165

Napoleone E, Di Santo A, Amore C, Baccante G, Di Febbo C, Porreca E, de Gaetano G, Donati MB and Lorenzet R (2007) Leptin induces tissue factor expression in human peripheral blood mononuclear cells: a possible link between obesity and cardiovascular risk? Journal of Thrombosis and Haemostosis in press

Napoleone E, Di Santo A, Bastone A, Peri G, Mantovani A, de Gaetano G, Donati MB and Lorenzet R (2002) Long pentraxin PTX3 upregulates tissue factor expression in human endothelial cells: a novel link between vascular inflammation and clotting activation. Arteriosclerosis, Thrombosis and Vascular Biology 22 782-787

Napoleone E, Di Santo A, Camera M, Tremoli E and Lorenzet R (2000) Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes. Circulation Research 86 139-143

Napoleone E, Di Santo A, Peri G, Mantovani A, De Gaetano G, Donati MB and Lorenzet R (2004) The long pentraxin PTX3 up-regulates tissue factor in activated monocytes: another link between inflammation and clotting activation. Journal of Leukocyte Biology 76 203-209

Napoli C, de Nigris F and Palinski W (2001) Multiple role of reactive oxygen species in the arterial wall. Journal of Cellular Biochemistry 82 674-682

Napolitano G, Bucci I, Giuliani C, Massafra C, Di Petta C, Devangelio E, Singer DS, Monaco F and Kohn LD (2002) High glucose levels increase major histocompatibility complex class I gene expression in thyroid cells and amplify interferon-gamma action. Endocrinology 143 1008-1017

Napolitano G, Montani V, Giuliani C, Di Vincenzo S, Bucci I, Todisco V, Laglia G, Coppa A, Singer DS, Nakazato M, Kohn LD, Colletta G and Monaco F (2000) Transforming growth factor-beta1 down-regulation of major histocompatibility complex class I in thyrocytes: coordinate regulation of two separate elements by thyroid-specific as well as ubiquitous transcription factors. Molecular Endocrinology 14 486-505

Nara H, Okamoto H, Minota S and Yoshio T (2006) Mouse monoclonal anti-human thrombomodulin antibodies bind to and activate endothelial cells through NF-kB activation in vitro.
Arthritis
and Rheum
atism 54 1629-1637

Narasimhan M and Ammanamanci S (2008) Curcumin blocks RON tyrosine kinase-mediated invasion of breast carcinoma cells. Cancer Research 68 5185-5192

Narayan P, Holt B, Tosti R and Kane LP (2006) CARMA1 is required for Akt-mediated NF-kB activation in T cells. Molecular and Cellular Biology 26 2327-2336

Narayana Y and Balaji KN (2008) Notch1 upregulation and signaling involved in mycobacterium bovis BCG induced SOCS3 expression in macrophages. Journal of Biological Chemistry in press

Narayanan BA, Narayanan NK, Desai D, Pittman B and Reddy BS (2004) Effects of a combination of docosahexaenoic acid and 1,4-phenylenebis (methylene) selenocyanate on cyclooxygenase-2, inducible nitric oxide synthase and b-catenin pathways in colon cancer cells. Carcinogenesis 25 2443-2449

Narayanan BA, Narayanan NK, Pittman B and Reddy BS (2004) Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model. Clinical Cancer Research 10 7727-7737

Narayanan BA, Narayanan NK, Re GG, Nixon DW (2003) Differential expression of genes induced by resveratrol in LNCaP cells: P53-mediated molecular targets. International Journal of Cancer 104 204-212

Narayanan K, Seufzer BJ, Brockman-Schneider RA, Gern JE, Balakrishnan A and Miyamoto S (2002) CD14-dependent activation of NF-kB by filarial parasitic sheath proteins. Cell Biology International 26 43-54

Narayanan NK, Narayanan BA and Reddy BS (2005) A combination of docosahexaenoic acid and celecoxib prevents prostate cancer cell growth in vitro and is associated with modulation of nuclear factor-kappaB, and steroid hormone receptors. International Journal of Oncology 26 785-792

Narayanan R (1994) Antisense therapy of cancer. In Vivo 8 787-794

Narayanan R, Higgins KA, Perez JR, Coleman TA and Rosen CA (1993) Evidence for differential functions of the p50 and p65 subunits of NF-kB with a cell adhesion model. Molecular and Cellular Biology 13 3802-3810

Narayanan R, Klement JF, Rubin SM, Higgins KA and Rosen CA (1992) Identification of a naturally occurring transforming variant of the p65 subunit of NF-kB. Science 256 367-370

Narbonnet S and Mariame B (2006) The Epstein-Barr virus oncoprotein LMP1 inhibits the activity of viral or cellular promoters without inducing cytostasis. Virology
350 381-393

Nardacci R, Antinori A, Larocca LM, Arena V, Amendola A, Perfettini JL, Kroemer G and Piacentini M (2005) Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis. American Journal of Pathology 167 695-704

Nareika A, He L, Game BA, Slate EH, Sanders JJ, London SD, Lopes-Virella MF and Huang Y (2005) Sodium lactate increases lipopolysaccharide-stimulated MMP and cytokine expression in U937 histiocytes by enhancing AP-1 and NFkB transcriptional activities. American Journal of Physiology: Endocrinology and Metabolism 289 E534-E542

Narieka A, Im YB, Game BA, Slate EH, Sanders JJ, London SD, Lopes-Virella MF and Huang Y (2008) High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kB and AP-1 activities. Journal of Endocrinology 196 45-55

Narindrasorasak S, Kulkarni P, Deschamps P, She YM and Sarkar B (2007) Characterization and copper binding properties of human COMMD1 (MURR1). Biochemistry 46 3116-3128

Narita M, Shimamura M, Imai S, Kubota C, Yajima Y, Takagi T, Shiokawa M, Inoue T, Suzuki M and SUzuki T (2008) Role of interleukin-1beta and tumor necrosis factor-alpha-dependent expression of cyclooxygenase-2 mRNA in thermal hyperalgesia induced by chronic inflammation in mice. Neuroscience in press

Narita N, Fujieda S, Tokuriki M, Takahashi N, Tsuzuki H, Ohtsubo T and Matsumoto H (2005) Inhibition of histone deacetylase 3 stimulates apoptosis induced by heat shock under acidic conditions in human maxillary cancer. Oncogene 24 7346-7354

Narumi S, Tebo JM, Finke JH and Hamilton TA (1992) IFN-g and IL-2 cooperatively activate NFkB in murine peritoneal macrophages. Journal of Immunology 149 529-534

Naruse S, Yamada J, Hamuro J, Kobayashi T, Mori K and Kinoshita S (2004) APC0576 decreases production of pro-inflammatory chemokine and extracellular matrix by human Tenon's capsule fibroblasts. Experimental Eye Research 79 223-230

Naschberger E, Werner T, Vicente AB, Guenzi E, Topolt K, Leubert R, Lubeseder-Martellato C, Nelson PJ and Sturzl M (2004) A NF-kB motif and ISRE cooperate in the activation of guanylate binding protein-1 expression by inflammatory cytokines in endothelial cells. Biochemical Journal 379 409-420

Nascimento DS, Vale AD, Tomas AM, Zou J, Secombes CJ, Dos Santos NM (2007) Cloning, promoter analysis and expression in response to bacterial exposure of sea bass (Dicentrarchus labrax L.) interleukin-12 p40 and p35 subunits. Mol
ecular Immunology 44 2277-2291

Nasr R, Chiari E, El-Sabban M, Mahieux R, Kfoury Y, Abdulhay M, Yazbeck V, Hermine O, de The H, Pique C and Bazarbachi A (2006) Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kB activation. Blood 107 4021-4029

Nasr R, El-Sabban ME, Karam JA, Dbaibo G, Kfoury Y, Arnulf B, Lepelletier Y, Bex F, de The H, Hermine O and Bazarbachi A (2005) Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma. Oncogene 24 419-430

Nasr R, Rosenwald A, El-Sabban ME, Arnulf B, Zalloua P, Lepelletier Y, Bex F, Hermine O, Staudt L, De The H and Bazarbachi A (2003) Arsenic/Interferon specifically reverses two distinct gene networks critical for the survival of HTLV-I infected leukemic cells. Blood 101 4576-4582

Nasuhara Y, Adcock IM, Catley M, Barnes PJ and Newton R (1999) Differential IkB kinase activation and IkBa degradation by interleukin-1beta and tumor necrosis factor-alpha in human U937 monocytic cells. Evidence for additional regulatory steps in kB-dependent transcription. Journal of Biological Chemistry 274 19965-19972 

Natarajan A, Wagner B and Sibilia M (2007) The EGF receptor is required for efficient liver regeneration. Proceedings of the National Academy of Sciences USA in press

Natarajan K, Manna SK, Chaturvedi MM and Aggarwal BB (1998) Protein tyrosine kinase inhibitors block TNF-induced activation of NF-kB, degradation of IkBa, nuclear transcription of p65 and subsequent gene expression. Achives of Biochemistry and Biophysics 352 59-70

Natarajan K, Singh S, Burke Jr TR, Grunberger D and Aggarwal BB (1996) Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kB. Proceedings of the National Academy of Sciences USA 93 9090-9095

Natarajan M, Mohan S,Konopinski R, Otto RA and Herman TS (2008) Induced telomerase activity in primary aortic endothelial cells by low-LET gamma radiation is mediated through NF-kB activation. British Journal of Radiation in press

 

Natarajan M, Nayak BK, Galindo C, Mathur SP, Roldan FN and Meltz ML (2006) Nuclear translocation and DNA-binding activity of NFKB (NF-kB) after exposure of human monocytes to pulsed ultra-wideband electromagnetic fields (1 kV/cm) fails to transactivate kB-dependent gene expression. Radiation Research 165 645-654

 

Natarajan M, V V, Szilagyi M, Roldan FN and Meltz ML (2002) NF-kB DNA-binding activity after high peak power pulsed microwave (8.2 GHz) exposure of normal human monocytes. Bioelectromagnetics 23 271-277

Natarajan P and Narayanan S (2007) Mycobacterium tuberculosis H37Rv induces monocytic release of interleukin-6 via activation of mitogen-activated protein kinases: inhibition by N-acetyl-l-cysteine. FEMS Immunol
ogy and Medical Microbiology in press

 

Natarajan R, Fisher B, Jones D and Fowler A (2002) Atypical mechanism of NF-kB activation during reoxygenation stress in microvascular endothelium: a role for tyrosine kinases. Free Radical Biology and Medicine 33 962

Natarajan R, Fisher BJ and Fowler 3rd AA (2007) Hypoxia inducible factor-1 modulates hemin-induced IL-8 secretion in microvascular endothelium. Microvasc
ular Research 73 163-172

Natarajan R, Fisher BJ, Jones DG, Ghosh S and Fowler AA (2002) Reoxygenating microvascular endothelium exhibits temporal dissociation of NF-kB and AP-1 activation. Free Radical Biology and Medicine 32 1033-1045

Natarajan R, Ghosh S, Fisher BJ, Diegelmann RF, Willey A, Walsh S, Graham MF and Fowler AA, 3rd (2001) Redox imbalance in Crohn's disease intestinal smooth muscle cells causes NF-kB-mediated spontaneous interleukin-8 secretion. Journal of Interferon aand Cytokine Research 21 349-359

Natarajan R, Reddy MA, Malik KU, Fatima S and Khan BV (2001) Signaling mechanisms of nuclear factor-kappab-mediated activation of inflammatory genes by 13-hydroperoxyoctadecadienoic acid in cultured vascular smooth muscle cells. Arteriosclerosis, Thrombosis and Vascular Biology 21 1408-1413

Natesan S, Molinari E, Rivera VM, Rickles RJ and Gilman M (1999) A general strategy to enhance the potency of chimeric transcriptional activators. Proceedings of the National Academy of Sciences USA 96 13898-13903 

Nath A, Conant K, Chen P, Scott C and Major EO (1999) Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon. Journal of Biological Chemistry 274 17098-17102 

Nath D (2001) Escape from death. Nature Reviews Molecular Cell Biology 2 644

Nath N, Giri S, Prasad R, Salem ML, Singh AK and Singh I (2005) 5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis. Journal of Immunology 175 566-574