|
References Relevant publications listed by the last name of
the first author.
La E and
Fischer SM (2001) Transcriptional regulation of intracellular IL-1 receptor
antagonist gene by IL-1 alpha in primary mouse keratinocytes. Journal of
Immunology 166 6149-6155 La S, Kim J, Kwon BS and Kwon B (2002) Herpes simplex virus type 1 glycoprotein D inhibits T-cell proliferation. Mol Cells 14 398-403 La Ferla K, Reimann C, Jelkmann W and Hellwig-Burgel T (2002) Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kB. FASEB Journal 16 1811-1813 La Ferla K, Seegert D and Schreiber S (2004) Activation of NF-kB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients. International Journal of Colorectal Disease 19 334-342 La Feurla-Bruhl K, Westhoff MA, Karl S, Kasperczyk H, Zwacka RM, Debatin KM and Fulda S (2007) NF-kB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition. Oncogene 26 571-582 La Frazia S, Amici C and Santoro MG (2006) Antiviral activity of proteasome inhibitors in herpes simplex virus-1 infection: role of nuclear factor-kB. Antiviral Therapy 11 995-1004 La Grutta S, Gagliardo R, Mirabella F, Pajno GB, Bonsignore G, Bousquet J, Bellia V and Vignola AM (2003) Clinical and biological heterogeneity in children with moderate asthma. American Journal of Respiratroy Critical Care Medicine 167 1490-1495
La Porta CA, Comolli R (1998) PKC-dependent modulation
of IkBa-NFkB pathway in low metastatic B16F1 murine melanoma cells and in
highly metastatic BL6 cells. Anticancer Research 18 2591-2597 La Rosa FA,
Pierce JW and Sonenshein GE (1994) Differential regulation of the c-myc
oncogene promoter by the NF-kB Rel family of transcription factors. Molecular
and Cellular Biology 14 1039-1044 La Rosa G, Cardali S, Genovese T, Conti A, Di Paola R, La Torre D, Cacciola F and Cuzzocrea S (2004) Inhibition of the nuclear factor-kB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in rats. J Neurosurg Spine 1 311-321 Laabi Y and
Strasser A (2000) Immunology. Lymphocyte survival-ignorance is Blys. Science
289 883-884 Laan M, Bozinovski S and Anderson GP (2004) Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells. Journal of Immunology 173 4164-4170 Labbe C, Goyette P, Lefebvre C, Stevens C, Green T, Tello-Ruiz MK, Cao Z, Landry AL, Stempak J, Annese V, Latiano A, Brant SR, Duerr RH, Taylor KD, Cho JH, Steinhart AH, Daly MJ, Silverberg MS, Xavier RJ and Rioux JD (2008) MAST3: a novel IBD risk factor that modulates TLR4 signaling. Genes & Immunity in press Labbozzetta M, Notarbartolo M, Poma P, Giannitrapani L, Cervello M, Montalto G and D'Alessandro N (2006) Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma. Annals of the New York Academy of Sciences 1089 268-275 Lacana E and
D'Adamio L (1999) Regulation of Fas ligand expression and cell death by
apoptosis-linked gene 4. Nature Medicine 5 542-547 Lacasa D, Taleb S, Keophiphath M, Miranville A and Clement K (2006) Macrophage-secreted factors impair human adipogenesis: involvement of proinflmmatory state in preadipocytes. Endocrinology in press LaCasse EC,
Baird S, Korneluk RG and MacKenzie AE (1998) The inhibitors of apoptosis (IAPs)
and their emerging role in cancer. Oncogene 17 3247-3259 Lacey D, Sampey A, Mitchell R, Bucala R, Santos L, Leech M and Morand E (2003) Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor. Arthritis and Rheumatitis 48 103-109 Lacey DL, Tan
HL, Lu J, Kaufman S, Van G, Qiu W, Rattan A, Scully S, Fletcher F, Juan T,
Kelley M, Burgess TL, Boyle WJ and Polverino AJ (2000) Osteoprotegerin ligand
modulates murine osteoclast survival in vitro and in vivo. American Journal of
Pathology 157 435-448 Lackman
RL and Cresswell P (2006) Exposure of the promonocytic cell line THP-1 to
Escherichia coli induces IFN-g-inducible lysosomal thiol reductase expression
by inflammatory cytokines. Lacoste J,
Cohen L and Hiscott J (1991) NF-kB activity in T cells stably expressing the
Tax protein of human T cell lymphotropic virus type I. Virology 184 553-562 Lacoste J,
D'Addario M, Roulston A, Wainberg MA and Hiscott J (1990) Cell-specific
differences in activation of NF-kB regulatory elements of human
immunodeficiency virus and beta interferon promoters by tumor necrosis factor.
Journal of Virology 64 4726-4734 Lacoste J,
Lanoix J, Pépin N and Hiscott J (1994) Interactions between HTLV-I Tax and
NF-kB/Rel proteins in T cells. Leukemia 8 S71-S76 Lacoste J,
Petropoulos L, Pépin N and Hiscott J (1994) Constitutive phosphorylation and
turnover of IkBa in human T-cell leukemia virus type I-infected and
Tax-expressing cells. Journal of Virology 69 564-569 Lacoste V, Nicot C, Gessain A, Valensi F, Gabarre J, Matta H, Chaudhary PM and Mahieux R (2007) In primary effusion lymphoma cells, MYB transcriptional repression is associated with v-FLIP expression during latent KSHV infection while both v-FLIP and v-GPCR become involved during the lytic cycle. British Journal of Haematology 138 487-501 Lad SP, Li J, da Silva Correia J, Pan Q, Gadwal S, Ulevitch RJ and Li E (2007) Cleavage of p65/RelA of the NF-kB pathway by Chlamydia. Proceedings of the National Academy of Sciences USA 104 2933-2938 Lad SP, Yang G, Scott DA, Chao TH, Correia JD, de lat Torre JC and Le E (2008) Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Molecular Immunology in press Lad SP, Yang G, Scott DA, Wang G, Nair P, Mathison J, Reddy VS and L E (2007) Chlamydial CT441 is a PDZ domain-containing tail-specific protease, that interferes with the NF-kB pathway of immune response. Journal of Bacteriology in press Lademarco MF,
McQuillan JJ, Rosen GD and Dean DC (1992) Characterization of the promoter for
vascular cell adhesion molecule-1 (VCAM-1). Journal of Biological Chemistry
267 16323-16329 Laderach D, Compagno D, Danos O, Vainchenker W and Galy A (2003) RNA interference shows critical requirement for NF-kB p50 in the production of IL-12 by human dendritic cells. Journal of Immunology 171 1750-1757 Ladetzki-Baehs K, Keller M, Kiemer AK, Koch E, Zahler S, Wendel A and Vollmar AM (2007) Atrial natriuretic peptide (ANP)-A regulator of NF-kB activation in vivo. Endocrinology 148 332-336 Ladner KJ, Caligiuri MA and Guttridge DC (2003) TNF regulated biphasic activation of NF-kB is required for cytokine-induced loss of skeletal muscle gene products. Journal of Biological Chemistry 278 2294-2303 Lafarge S, Hamzeh-Cognasse H, Chavarin P, Genin C, Garraud O and Cognasse F (20070 A flow cytometry technique to study intracellular signals NF-kB and STAT3 in peripheral blood mononuclear cells. BMC Molecular Biology 8 64 Lafuente N, Matesanz N, Azcutia V, Romacho T, Nevado J, Rodriguez-Manas L, Moncada S, Peiro C and Sanchez-Ferrer CF (2008) The deleterious effect of high concentrations of D-glucose requires pro-inflammatory preconditioning. Journal of Hypertension 26 478-485 Laga M, Cottyn A, Van Herreweghe F, Berghe WV, Haegeman G, Van Oostveldt P, Vanderkerckhove J and Vancompernolle K (2007) Methylglyoxal suppresses TNF-alpha-induced NF-kB activation by inhibiting NF-kB DNA-binding. Biochemical Pharmacology 74 579-589 Lagoumintzis G, Xaplanteri P, Dimitracopoulos G and Paliogianni F (2007) TNF-a induction by Pseudomonas aeruginosa lipopolysaccharide or Slime-glycolipoprotein in human monocytes is regulated at the level of mitogen-activated protein kinase activity: a distinct role of Toll-like receptor 2 and 4. Scandinavian Journal of Immunology in press Lćgreid A,
Medvedev A, Nonstad U, Bombara MP, Ranges G, Sundan A and Espevik T (1994)
Tumor necrosis factor receptor p75 mediates cell-specific activation of
nuclear factor kB and induction of human cytomegalovirus. Journal of
Biological Chemistry 269 7785-7791 Laflamme N
and Rivest S (1999) Effects of systemic immunogenic insults and circulating
proinflammatory cytokines on the transcription of the inhibitory factor kBa
within specific cellular populations of the rat brain. Journal of
Neurochemistry 73 309-321 Laflamme N,
Lacroix S and Rivest S (1999) An essential role of interleukin-1beta in
mediating NF-kB activity and COX-2 transcription in cells of the blood-brain
barrier in response to a systemic and localized inflammation but not during
endotoxemia. Journal of Neuroscience 19 10923-10930 Laflamme N,
Soucy G and Rivest S (2001) Circulating cell wall components derived from
gram-negative, not gram-positive, bacteria cause a profound induction of the
gene-encoding Toll-like receptor 2 in the CNS. Journal of Neurochemistry 79
648-657 Lafuente MJ, Martin P, Garcia-Cao I, Diaz-Meco MT, Serrano M and Moscat J (2003) Regulation of mature T lymphocyte proliferation and differentiation by Par-4. EMBO Journal 22 4689-4698 Lagadec P, Griessinger E, Nawrot MP, Fenouille N, Colosetti P, Imbert V, Mari M, Hofman P, Czerucka D, Rousseau D, Berard E, Dreano M and Peyron JF (2008) Pharmacological targeting of NF-kappaB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells. British Journal of Cancer in press Lagarde
SM, Ten Kate FJ, Richel DJ, Offerhaus GJ and van Lanschot JJ (2007) Molecular
prognostic factors in adenocarcinoma of the esophagus and gastroesophageal
junction. Lagoumintzis G, Christofidou M, Dimitracopoulos G and Paliogianni F (2003) Pseudomonas aeruginosa slime glycolipoprotein is a potent stimulant of tumor necrosis factor alpha gene expression and activation of transcription activators nuclear factor kB and Activator Protein 1 in human monocytes. Infection & Immunity 71 4614-4622 Lagresle C,
Mondičre P, Bella C, Krammer PH and Defrance T (1996) Concurrent engagement
of CD40 and the antigen receptor protects naive and memory human B cells from
APO-1/Fas-mediated apoptosis. Journal of Experimental Medicine 183 1377-1388 Laguillier C, Hbibi AT, Baran-marszak F, Metelev V, Cao A, Bymbalista F, Bogdanov Jr A and Fagard R (2007) Cell death in NF-kB-dependent tumour cell lines as a result of NF-kB trapping by linker-modified hairpin decoy oligonucleotide. FEBS Letters in press Lagunas VM and Melendez-Zaigla J (2008) Nuclear factor-kB as a resistance factor to platinum-based antineoplasic drugs. Met Based Drugs 2008 576104 Lagunoff M and Carroll PA (2003) Inhibition of apoptosis by the gamma-herpesviruses. International Review of Immunology 22 373-399 Lahat A, Horin SB, Lang A, Fudim E, PIcard O and Chowers Y (2008) Lidocaine down-regulates nuclear factor-kB signalling and inhibits cytokine production and T cell proliferation. Clinical and Experimental Immunology in press Lahdenpohja N
and Hurme M (1998) CD28-mediated activation in CD45RA+ and CD45RO+ T cells:
enhanced levels of reactive oxygen intermediates and c-Rel nuclear
translocation in CD45RA+ cells. Journal of Leukocyte Biology 63 775-780 Lahdenpohja
N, Henttinen T and Hurme M (1996) Activation of the protein kinase A increases
the DNA-binding and transcriptional activity of c-Rel in T cells. Scandanavian
Journal of Immunology 43 640-645 Laherty CD,
Hu HM, Opipari AW, Wang F and Dixit VM (1992) The Epstein-Barr virus LMP-1
gene product induces A20 zinc finger protein expression by activating nuclear
factor kB. Journal of Biological Chemistry 267 24157-24160 Laherty CD,
Perkins ND and Dixit VM (1993) Human T cell leukemia virus type I Tax and
phorbol 12-myristate 13-acetate induce expression of the A20 zinc finger
protein by distinct mechanisms involving nuclear factor kB. Journal of
Biological Chemistry 268 5032-5039 Lahiri DK (2004) Apolipoprotein e as a target for developing new therapeutics for Alzheimer's disease based on studies from protein, RNA, and regulatory region of the gene. Journal of Molecular Neuroscience 23 225-234 Lahiri DK,
Nall C and Ge YW (1999) Promoter activity of the beta-amyloid precursor
protein gene is negatively modulated by an upstream regulatory element. Brain
Research Molecular Brain Research 71 32-41 Lahti A, Jalonen U, Kankaanranta H and Moilanen E (2003) c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages. Molecular Pharmacology 64 308-315 Lahti A, Kankaanranta H and Moilanen E (2002) P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production. European Journal of Pharmacology 454 115-123 Lai C, Jiang X and Li X (2006) Development of luciferase reporter-based cell assays. Assay Drug Development Technologies 4 307-315 Lai CH, Fang SH, Rao YK, Geethanglili M, Tang CH, Lin YJ, Hung CH, Wang WC and Tzeng YM (2008) Inhibition of Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells by Phyllanthus urinaria extracts. Journal of Ethnopharmacology in press Lai CS, Li S, Chai CY, Lo CY, Ho CT, Wang YJ and Pan MH (2007) Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. Carcinogenesis in press Lai J-H and
Tan T-H (1994) CD28 signaling causes a sustained down-regulation of IkBa which
can be prevented by the immunosuppressant rapamycin. Journal of Biological
Chemistry 269 30077-30080 Lai JH,
Horvath G, Li Y and Tan TH (1995) Mechanisms of enhanced nuclear translocation
of the transcription factors c-Rel and NF-kB by CD28 costimulation in human T
lymphocytes. Annals of the New York Academy of Science 766 220-223 Lai J-H,
Horvath G, Subleski J, Bruder J, Ghosh P and Tan T-H (1995) RelA is a potent
transcriptional activator of the CD28 response element within the interleukin
2 promoter. Molecular and Cellular Biology 15 4260-4271 Lai JL,
Zandeck M, Mary JY, Bernandi F, Izydorczyk V, Flatchip M, Morel P, Jovet JP,
Bautos F and Facon T (1995) Improved cytogenetics in multiple myeloma: a study
of 151 patients including 117 patients at diagnosis. Blood 85 2490-2497 Lai MM (2000)
Hepatitis viruses and signal transduction: true to the core? Hepatology 32
427-429 Lai PC, Smith J, Bhangal G, Chaudhry KA, Chaudhry AN, Keith JR JC, Tam FW, Pusey CD and Cook HT (2005) Interleukin-11 reduces renal injury and glomerular NF-kB activity in murine experimental glomerulonephritis. Nephron Exp Nephrol 101 e146-e154 Lai TH, Fong YC, FU WM, Yang RS and Thang CH (2008) Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins. Prostate in press Lai WC, Zhou M, Shankavaram U, Peng G, Wahl LM (2003) Differential regulation of lipopolysaccharide-induced monocyte matrix metalloproteinase (MMP)-1 and MMP-9 by p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases. Journal of Immunology 170 6244-6249 Lai Yl and Yamaguchi M (2007) Phytocomponent p-hydroxycinnamic acid inhibits osteoclast-like cell formation in mouse bone marrow cultures. International Journal of Molecular Medcine 19 123-128 Laín de Lera
T, Folgueira L, Martin AG, Dargemont C, Pedraza M-A, Garcia-Matin A, Bermejo
M, Bonay P, Fresno M and Alcami J (1999) Expression of IkBa in the nucleus of
human peripheral blood T lymphocytes. Oncogene 18 1581-1588 Laine ML, Morre SA, Murillo LS, van Winkelhoff AJ and Pena AS (2005) CD14 and TLR4 gene polymorphisms in adult periodontitis. Journal of Dental Research 84 1042-1046 Laine PS, Schwartz EA, Wang Y, Zhang WY, Karnik SK, Musi N and Reaven PD (2007) Palmitic acid induces IP-10 expression in human macrophages via NF-kB activation. Biochemical and Biophysical Research Communications in press Laird SM,
Tuckerman EM, Cork BA and Li TC (2000) Expression of nuclear factor kB in
human endometrium; role in the control of interleukin 6 and leukemia
inhibitory factor production. Molecular Human Reproduction 6 34-40 Laitinen S, Fontaine C, Fruchart J and Staels B (2005) The role of the orphan nuclear receptor Rev-Erbalpha in adipocyte differentiation and function. Biochimie 87 21-25 Lajoie-Kadoch S, Joubert P, Letuve S, Halayko AJ, Martin JG, Soussi-Gounni A and Hamid Q (2006) TNFa and IFNg inversely modulate expression of the IL-17E receptor in airway smooth muscle cells. American Journal of Physiology: Lung Cell and Molecular Physiology 290 L1238-L1246 Lake BB, Ford R and Kao KR (2001) Xrel3 is required for head development in Xenopus laevis. Development 128 263-273 Lakhani SR (2004) Putting the brakes on cylindromatosis? New England Journal of Medicine 350 187-188 Lakics V,
Medvedev AE, Okada S, Vogel SN (2000) Inhibition of LPS-induced cytokines by
Bcl-xL in a murine macrophage cell line. Journal of Immuno1ogy 65 2729-2737 Lakshmanan U and Porter AG (2007) Caspase-4 interacts with TNF receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kB-dependent production of IL-8 and CC chemokine ligand 4 (Macrophage-Inflammatory Protein-1 ). Journal of Immunology 179 8480-8490 Lakshminarayanan
V, Drab-Weiss EA and Roebuck KA (1998) H2O2 and tumor necrosis factor-a induce
differential binding of the redox-responsive transcription factors AP-1 and
NF-kB to the interleukin-8 promoter in endothelial and epithelial cells.
Journal of Biological Chemistry 273 32670-32678 Lal MA,
Brismar H, Eklof AC and Aperia A (2002) Role of oxidative stress in advanced
glycation end product-induced mesangial cell activation. Kidney International
61 2006-2014 Lallemand F,
Mazars A, Prunier C, Bertrand F, Kornprost M, Gallea S, Roman-Roman S, Cherqui
G and Atfi A (2001) Smad7 inhibits the survival nuclear factor kB and
potentiates apoptosis in epithelial cells. Oncogene 20 879-884 Lallena M-J,
Diaz-Meco MT, Bren G, Payá CV and Moscat J (1999) Activation of IkB kinase b
by protein kinase C isoforms. Molecular and Cellular Biology 19 2180-2188 Lalli CA, Pauli JR, Prada PO, Cintra DE, Ropelle ER, Velloso LA and Saad MJ (2008) Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet. Metabolism 57 57-65 Lalmanach-Girard
AC, Chiles TC, Parker DC and Rothstein TL (1993) T cell-dependent induction of
NF-kB in B cells. Journal of Experimental Medicine 177 1215-1219 Lalor DJ, Truong B, Henness S, Blake AE, Ge Q, Ammit AJ, Armour CL and Hughes JM (2004) Mechanisms of serum potentiation of GM-CSF production by human airway smooth muscle cells. American Journal of Physiology: Lung Cell and Molecular Physiology 287 L1007-L1016 Lalaor PF, Sun PJ, Weston CJ, Martin-Santos A, Wakelam MJ and Adams DH (2007) Activation of vascular adhesion protein-1 on liver endothelium results in an NF-kB-dependent increase in lymphocyte adhesion. Hepatology 45 465-474 Lalor PF, Tuncer C, Weston C, Martin-Santos A, Smith DJ and Adams DH (2007) Vascular adhesion protein-1 as a potential therapeutic target in liver disease. Annals of the New York Academy of Sciences 1110 485-596 Lam AG,
Koppal T, Akama KT, Guo L, Craft JM, Samy B, Schavocky JP, Watterson DM and
Van Eldik LJ (2001) Mechanism of glial activation by S100B: involvement of the
transcription factor NFkB. Neurobiology of Aging 22 765-772 Lam AP and Dean DA (2008) Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells. Journal of Gene Medicine in press Lam LT, Davis RE, Pierce J, Hepperle M, Xu Y, Hottelet M, Nong Y, Wen D, Adams J, Dang L and Staudt LM (2005) Small molecule inhibitors of IkB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. Clinical Cancer Research 11 28-40 Lam LT, Wright G, Davis RE, Lenz G, Farinha P, Dang L, Chan JW, Rosenwald A, Gascoyne R and Staudt LM (2007) Cooperative signaling through the STAT3 and NF-kB pathways in subtypes of diffuse large B cell lymphoma. Blood in press Lam QLK, Zheng B-J, Jin D-Y, Cao X and Lu L (2007) Leptin induces CD40 expression through the activation of AKT in murine dendritic cells. Journal of Biological Chemistry 282 27587-27597 Lamas O, Moreno-Aliaga MJ, Martinez JA and Marti A (2003) NF-kB-binding activity in an animal diet-induced overweightness model and the impact of subsequent energy restriction. Biochemical and Biophysical Research Communications 311 533-539 LaMarco K,
Thompson CC, Byers BP, Walton EM and McKnight SL (1991) Identification of Ets-
and Notch-related subunits in GA binding protein. Science 253 789-792 Lamb JA, Ventura JJ, Hess P, Flavell RA and Davis RJ (2003) JunD mediates survival signaling by the JNK signal transduction pathway. Molecular Cell 11 1479-1489 Lambeng N,
Michel PP, Brugg B, Agid Y and Ruberg M (1999) Mechanisms of apoptosis in PC12
cells irreversibly differentiated with nerve growth factor and cyclic AMP.
Brain Research 821 60-68 Lambert C, Li J, Jonscher K, Yang TC, Reigan P, Quintana M, Harvey J and Freed BM (2007) Acrolein inhibits cytokine gene expression by alkylating cysteine and arginine residues in the NF-kB1 DNA-binding domain. Journal Biological Chemistry 282 19666-19675 Lambert C, Oury C, Dejardin E, Chariot A, Piette J, Malaise M, Merville MP and Franchimont N (2007) Further insights in the mechanisms of interleukin-1beta stimulation of osteoprotegerin in osteoblast-like cells. Journal of Bone and Mineral Research in press Lambert JD and Yang CS (2003) Mechanisms of cancer prevention by tea constituents. Journal of Nutrition 133 3262S-3267S Lambert PF,
Ludford-menting MJ, Deacon NJ, Kola I and Doherty RR (1997) The nfkb1
promoter is controlled by proteins of the Ets family. Molecular Biology of the
Cell 8 313-323 Lambert S, Yu
H, Prchal JT, Lawler J, Ruff P, Speicher D, Cheung MC, Kan YW and Palek J
(1990) cDNA sequence for human erythrocyte ankyrin. Proceedings of the
National Academy of Sciences USA 87 1730-1734 Lamberti A, Petrella A, Pascale M, Romano MF, Bisogni R, Vita N, Venuta S and Turco MC (2004) Activation of NF-kB/Rel transcription factors in human primary peripheral blood mononuclear cells by interleukin 7. Biology and Chemistry 385 415-417 Lamberti A, Romano MF, Agosti V, Garbi C, Sun SC, Bond HM, Bonelli P, Turco MC and Venuta S (1999) Regulation of cell survival in CD95-induced T cell apoptosis: role of NF-kB/Rel transcription factors. Apoptosis 4 179-186
Lamberti
C, Lin KM, Yamamoto Y, Verma U, Verma IM, Byers S and
Gaynor RB (2001)
Regulation of
b-catenin function by the IkB kinases.
Journal of Biological Chemistry 276 42276-42286 Lamhamedi-Cherradi SE, Zheng S, Hilliard BA, Xu L, Sun J, Alsheadat S, Liou HC and Chen YH (2003) Transcriptional regulation of type I diabetes by NF-kB. Journal of Immunology 171 4886-4892 Lamkanfi M, Declercq W, Vanden Berghe T and Bendenabeele P (2006) Caspases leave the beaten track: caspase-mediated activation of NF-kB. Journal of Cell Biology 173 165-171 Lamkanfi M, Denecker G, Kalai M, D'hondt K, Meeus A, Declercq W, Saelens X and Vandenabeele P (2004) INCA: a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation. Journal of Biological Chemistry 279 51729-51738 Lamkanfi M, D'hondt K, Vande Walle L, van Gurp M, Denecker G, Demeulemeester J, Kalai M, Declercq W, Saelens X, Vandenabeele P (2005) A novel caspase-2 complex containing TRAF2 and RIP1. Journal of Biological Chemistry 280 6923-6932 Lamkanfi M, Festjens N, Declercq W, Berghe TV and Vandenabeele P (2007) Caspases in cell survival, proliferation and differentiation. Cell Death and Differentiation 14 44-55 Lamkanfi M, Kalai M, Saelens X, Declercq W and Vandenabeele P (2004) Caspase-1 activates NF-kB independent of its enzymatic activity. Journal of Biological Chemistry 279 24785-24793 Lammerding J, Schulze PC, Takahashi T, Kozlov S, Sullivan T, Kamm RD, Stewart CL and Lee RT (2004) Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. Journal of Clinical Investigation 113 370-378 LaMonica R, Kocer SS, Nazarova J, Dowling W, Geimonen E, Shaw RD and Mackow ER (2001) VP4
differentially regulates TRAF2 signaling, disengaging JNK activation while
directing NF-kB to effect rotavirus specific cellular responses. Journal of
Biological Chemistry 276 19889-19896 Lamothe B, Besse A, Campos AD, Webster Wk, Wu H and Darnay BG (2007) Site-specific Lys-63-linked TRAF6 auto-ubiquitination is a critical determinantof IKK activation. Journal of Biological Chemistry 282 4102-4112 Lamothe B, Campos AD, Webster WK, Gopinathan A, Hur L and Darnay BG (2008) The RING domain and first Zinc-finger of TRAF6 coordinate signaling by IL-1, LPS, and RANKL. Journal of Biological Chemistry in press Lamothe B, Webster WK, Gopinathan A, Besse A, Campos AD and Darnay BG (2007) TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation. Biochemical and Biophysical Research Communications in press Lampronti I, Bianchi N, Borgatti M, Fabbri E, Vizziello L, Khan MT, Ather A, Brezena D, Tahir MM and Gambari R (2005) Effects of vanadium complexes on cell growth of human leukemia cells and protein-DNA interactions. Oncology Reports 14 9-15 Lampronti
I, Khan MT, Bianchi N, Ather A, Borgatti M, Vizziello L, Fabbri E and Gambari
R (2006) Bangladeshi medicinal plant extracts inhibiting molecular
interactions between nuclear factors and target DNA sequences mimicking NF-kB
binding sites. Lamsoul I, Lodewick J, Lebrun S, Brasseur R, Burny A, Gaynor RB and Bex F (2005) Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kB activation by the human T-cell leukemia virus Tax oncoprotein. Molecular and Cellular Biology 25 10391-10406 Lan CC, Yu HS, Wu CS, Kuo HY, Chai CY and Chen GS (2005) FK506 inhibits tumour necrosis factor-alpha secretion in human keratinocytes via regulation of nuclear factor-kB. British Journal of Dermatology 153 725-732 Lan KP, Wang CJ, Hsu JD, Chen KM, Lai SC and Lee HH (2004) Induced eosinophilia and proliferation in Angiostrongylus cantonensis-infected mouse brain are associated with the induction of JAK/STAT1, IAP/NF-kB and MEKK1/JNK signals. Journal of Helminthology 78 311-317 Lan L, Zhao F, Wang Y and Zeng H (2006) The mechanism of apoptosis induced by a novel thioredoxin reductase inhibitor in A549 cells: Possible involvement of nuclear factor-kB-dependent pathway. European Journal of Pharmacology in press Lan Y, Zhou Q
and Wu ZL (2004) NF-kB involved in transcription enhancement of TGF-beta1
induced by Ox-LDL in rat mesangial cells. Chinese Medical Journal (English) 117
225-230 Land SC and Wilson SM (2005) Redox regulation of lung development and
perinatal lung epithelial function. Antioxidant and Redox Signaling 7 92-107 Landesman-Bollag
E, Romieu-Mourez R, Song DH, Sonenshein GE, Cardiff RD and Seldin DC (2001)
Protein kinase CK2 in mammary gland tumorigenesis. Oncogene 20 3247-3257 Landi S, Moreno V, Gioia-Patricola L, Guino E, Navarro M, de Oca J, Capella G, Canzian F; Bellvitge Colorectal Cancer Study Group (2003) Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. Cancer Research 63 3560-3566 Landowski TH, Olashaw NE, Agrawal D and Dalton WS (2003) Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-kB (RelB/p50) in myeloma cells. Oncogene 22 2417-2421
Landsvater RM,
de Wit MJ, Peterson LF, Sinke RJ, van Kessel AG, Lips CJM and Höppener JWM
(1997) Exclusion of the Nuclear Factor-kB3 (RELA) gene as candidate for the
multiple endocrine neoplasia type 1 (MEN 1) gene. Biochemical and Molecular
Medicine 60 76-79 Lang A, Lahav M, Sakhnini E, Barshack I, Fidder HH, Avidan B, Bardan E, Hershkoviz R, Bar-Meir S and Chowers Y (2004) Allicin inhibits spontaneous and TNF-alpha induced secretion of proinflammatory cytokines and chemokines from intestinal epithelial cells. Clinical Nutrition 23 1199-1208
Lang CH, Nystrom GJ and Frost RA (1999) Regulation of IGF binding protein-1 in hep G2
cells by cytokines and reactive oxygen species. American Journal of Physiology
276 G719-G727 Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N and Vallon V (2006) Pathophysiological signifcance of the serum-and glucocotricoid-inducible kinase isoforms. Physiological Reviews 86 1151-1178 Lang H, Schulte BA and Schmiedt RA (2005) Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neurons. Journal of the Association for Research in Otolaryngology 6 63-71 Lang H, Schulte BA, Zhou D, Smythe N, Spicer SS and Schmiedt RA (2006) Nuclear factor kB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss. Journal of Neuroscience 26 3541-3550 Lang KS, Weigert C, Braedel S, Fillon S, Palmada M, Schleicher E, Rammensee HG and Lang F (2003) Inhibition of interferon-gamma expression by osmotic shrinkage of peripheral blood lymphocytes. American Journal of Physiology: Cell Physiology 284 C200-C208 Lang MF, Schneider A, Kruger C, Schmid R, Dziarski R and Schwaninger M (2007) Peptidoglycan recognition protein-S (PGRP-S) is upregulated by NF-kB. Neuroscience Letters in press Lang V, Janzen J, Fischer GZ, Soneji Y, Beinke S, Salmeron A, Allen H, Hay RT, Ben-Neriah Y and Ley SC (2003) betaTrCP-mediated proteolysis of NF-kB1 p105 requires phosphorylation of p105 serines 927 and 932. Molecular and Cellular Biology 23 402-413 Lang V, Symons A, Watton SJ, Janzen J, Soneji Y, Beinke S, Howell S and Ley SC (2004) ABIN-2 forms a ternary complex with TPL-2 and NF-kB1 p105 and is essential for TPL-2 protein stability. Molecular and Cellular Biology 24 5235-5248 Lang-Lazdunski L, Blondeau N, Jarretou G, Lazdunski M and Heurteaux C (2003) Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats. Journal of Vascular Surgery 38 564-575 Langat DK, Morales PJ, Omwandho CO and Fazleabas At (2007) Polymorphisms in the Paan-AG promoter influence NF-kB binding and transcriptional activity. Immunogenetics in press
Langen RC,
Schols AM, Kelders MC, Wouters EF and Janssen-Heininger YM (2001) Inflammatory
cytokines inhibit myogenic differentiation through activation of nuclear
factor-kB. FASEB Journal 15 1169-1180 Langen RC, Van Der Velden JL, Schols AM, Kelders MC, Wouters EF and Janssen-Heininger YM (2004) Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization. FASEB Journal 18 227-237 Langouche L, Vanhorebeek I, Vlasselaers D, Vander Perre S, Wouters PH, Skogstrand K, Hansen TK and Van den Berghe G (2005) Intensive insulin therapy protects the endothelium of critically ill patients. Journal of Clinical Investigation 115 2277-2286
Laniado-Schwartzman M, Lavrovsky Y, Stoltz RA, Conners
MS, Falck JR, Chauhan K and Abraham NG (1994) Activation of nuclear factor kB
and oncogene expression by 12(R)-hydoxyeicosatrienoic acid, an angiogenic
factor in microvessel endothelial cells. Journal of Biological Chemistry 269
24321-24327 Lanoix J,
Lacoste J, Pepin N, Rice N and Hiscott J (1994) Overproduction of NFKB2
(lyt-10) and c-Rel: a mechanism for HTLV-I Tax-mediated trans-activation
via the NF-kB signalling pathway. Oncogene 9 841-852 Lantner F, Starlets D, Gore Y, Slaishon L, Yamit-Hezi A, Dikstein R, Leng L, Bucala R, Machluf Y, Oren M and Schachar I (2007) CD74 induces TAp63 expression leading to B cell survival. Blood in press Lanza L,
Scudeletti M, Monaco E, Monetti M, Puppo F, Filaci G and Indiveri F (1999)
Possible differences in the mechanism(s) of action of different glucocorticoid
hormone compounds. Annals of the New York Academy of Sciences 876 193-197 Lao Q, Fukamachi T, Saito H, Kuge O, Nishijima M and Kobayashi H (2006) Requirement of an IkB-beta COOH terminal region protein for acidic-adaptation in CHO cells. Journal of Cellular Physiology 207 238-243 Lao Q, Kuge O, Fukamachi T, Kakegawa T, Saito H, Nishijima M and Kobayashi H (2004) An IkB-b COOH terminal region protein is essential for the proliferation of CHO cells under acidic stress. Journal of Cell Physiology 203 186-192 Laos S, Baeckstrom D and Hansson GC (2006) Inhibition of NF-kB activation and chemokine expression by the leukocyte glycoprotein, CD43, in colon cancer cells. International Journal of Oncology 28 695-704 Lapointe R,
Lemieux R and Darveau A (1996) HIV-1 LTR activity in human CD40-activated B
lymphocytes is dependent on NF-kB. Biochemical and Biophysical Research
Communications 229 959-964 Lapouge G, Marcias G, Erdmann E, Kessler P, Cruchant M, Serra S, Bergerat JP and Ceraline J (2008) Specific properties of a C-terminal truncated androgen receptor detected in hormone refractory prostate cancer. Advances in Experimental Medicine and Biology 617 529-534 Lappanen T, Jalonen U, Kankaanranta H, Tuominen R, and Moilanen E (2008) Inhibition of protein kinase C betaII downregulates tristetraprolin expression in activated macrophages. Inflammation Research 57 230-240 Lappas M, Permezel M and Rice GE (2003) N-acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. Journal of Clinical Endocrinology and Metabolism 88 1723-1729
Lappas M,
Permezel M, Georgiou HM and Rice GE (2002) Nuclear factor kB regulation of
proinflammatory cytokines in human gestational tissues in vitro. Biol Reprod
67 668-673 Lappas M, Permezel M, Georgiou HM and Rice GE (2004) Regulation of phospholipase isozymes by nuclear factor-kB in human gestational tissues in vitro. Journal of Clinical Endocrinology and Metabolism 89 2365-2372 Lappas M, Permezel M, Ho PW, Moseley JM, Wlodek ME and Rice GE (2004) Effect of nuclear factor-kB inhibitors and peroxisome proliferator-activated receptor-gamma ligands on PTHrP release from human fetal membranes. Placenta 25 899-704
Lappas M, Permezel M, Holdsworth SJ, Zanoni G, Porta A and Rice
GE (2007) Antiinflammatory effects of the cyclopentenone isoprostane
15-A(2)-IsoP in human gestational tissues. Lappas M, Permezel M and Rice GE (2005) Leptin and adiponectin stimulate the release of pro-inflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via NF-kB, PPAR-gamma and ERK 1/2. Endocrinology 146 3334-3342 Lappas M, Permezel M and Rice GE (2006) 15-deoxy-delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues. Placenta in press Lappas M, Permezel M and Rice GE (20067) Advanced glycation endproducts mediate pro-inflammatory actions in human gestational tissues via nuclear factor-kB and extracellular signal-regulated kinase 1/2. Journal of Endocrinology 193 269-277 Lappas M and Rice GE (2004) Phospholipase A(2) isozymes in pregnancy and parturition. Prostaglandins Leukot Essent Fatty Acids 70 87-100 Lappas M and Rice GE (2006) The role and regulation of the nuclear factor kB signalling pathway in human labour. Placenta in press Lappas M, Yee K, Permezel M and Rice GE (2004) Sulphasalazine and BAY 11-7082 interfere with the NF-kB and IKK-b pathway to regulate the release of pro-inflammatory cytokines from human adipose tissue and skeletal muscle, in vitro. Endocrinology 146 1491-1497 Lappas M, Yee K, Permezel M and Rice GE (2005) Lipopolysaccharide and TNF-a activate the nuclear factor kB pathway in the human placental JEG-3 cells. Placenta 186 457-465
Lapteva N,
Ide K, Nieda M, Ando Y, Hatta-Ohashi Y, Minami M, Dymshits G, Egawa K, Juji T
and Tokunaga K (2002) Activation and suppression of renin-angiotensin system
in human dendritic cells. Biochemical and Biophysical Research Communications
296 194-200 Lara Jr PN, Bold RJ, Mack PC, Davies AM, Gumerlock PH and Gandara DR (2005) Proteasome inhibition in small-cell lung cancer: preclinical rationale and clinical applications. Clinical Lung Cancer 7 S67-S71 Lara Jr PN, Davies AM, Mack PC, Mortenson MM, Bold RJ, Gumerlock PH and Gandara DR (2004) Proteasome inhibition with PS-341 (bortezomib) in lung cancer therapy. Seminars in Oncology 31 40-46
Larabee JL, Hocker JR, Lerner MR, Lightfoot SA, Cheung JY, Brackett DJ,
Gallucci Rm and Hanas JS (2005) Stress induced in heart and other tissues by
rat dermal exposure to JP-8 fuel.
Larabi M,
Legrand P, Appel M, Gil S, Lepoivre M, Devissaguet J, Puisieux F and Barratt G
(2001) Reduction of no synthase expression and tumor necrosis factor alpha
production in macrophages by amphotericin B lipid carriers. Antimicrobial Agents
and Chemotherapy 45 553-562 Largo R, Alvarez-Soria MA, Diez-Ortego I, Calvo E, Sanchez-Pernaute O, Egido J and Herrero-Beaumont G (2003) Glucosamine inhibits IL-1beta-induced NFkB activation in human osteoarthritic chondrocytes. Osteoarthritis Cartilage 11 290-298 Larmonier N, Cantrell J, Lacasse C, Li G, Janikashvili N, Situ E, Sepassi M, Andreansky S and Katsanis E (2008) Chaperone-rich tumor cell lysate-mediated activation of antigen-presenting cells resists regulatory T cell suppression. Journal of Leukocyte Biology in press Larmonier N, Marron M, Zeng Y, Cantrell J, Romanoski A, Sepassi M, Thompson S, Chen X, Andreansky S and Katsanis E (2007) Tumor-derived CD4(+)CD25 (+) regulatory T cell suppression of dendritic cell function involves TGF-beta and IL-10. Cancer Immunology and Immunotherapy 56 48-59 Larmonier N, Merino D, Nicolas A, Cathelin D, Besson A, Bateman A, Solary E, Martin F,Katsanis E and Bonnotte B (2006) Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading. Apoptosis in press
Larose RN and
Svoian M (1965) Avian lymphomatosis. IX. Mortality and seriological response
of chickens of various ages to graded doses of T-strain. Avian Diseases 9
604-610 Larousserie F, Bardel E, Coulomb L'hermine A, Canioni D, Brousse N, Kastelein R and Dvergne O (2006) Variable expression of Epstein-Barr virus-induced gene 3 during normal B-cell differentiation and among B-cell lymphomas. Journal of Pathology in press Larousserie F, Bardel E, Pflanz S, Arnulf B, Lome-Maldonado C, Hermine O, Bregeaud L, Perennec M, Brousse N, Kastelein R and Devergne O (2005) Analysis of Interleukin-27 (EBI3/p28) expression in Epstein-Barr Virus- and Human T-Cell Leukemia Virus Type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. American Journal of Pathology 16 1217-1228 Laroux FS,
Pavlick KP, Hines IN, Kawachi S, Harada H, Bharwani S, Hoffman JM and Grisham
MB (2001) Role of nitric oxide in inflammation. Acta Physiologica Scandinavica 173 113-118 Larregina AT, Morelli AE, Tkacheva O, Erdos G, Donahue C, Watkins SC, Thomson AW and Falo LD (2003) Highly efficient expression of transgenic proteins by naked DNA transfected dendritic cells through terminal differentiation. Blood 103 811-819 Larsen AK, Seternes OM, Larsen M, Aasmoe L and Bang B (2008) Salmon trypsin stimulates the expression of interleukin-8 via protease-activated receptor-2. Toxicology and Applied Pharmacology in press Larsen L, Storling J, Darville M, Eizirik DL, Bonny C, Billestrup N and Mandrup-Poulsen T (2005) Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kB-mediated gene expression in insulin-producing INS-1E cells. Diabetologia 48 2582-2590 Larsen M, Tazzyman S, Lund EL, Junker N, Lewis CE, Kristjansen PE and Murdoch C (2008) Hypoxia-induced secretion of macrophage migration-inhibitory factor from MCF-7 breast cancer cells is regulated in a hypoxia-inducible factor-independent manner. Cancer Letters in press Larson CJ, Li
YW, Mercurio F and Muller R (1999) Functional characterization of a purified,
recombinant NF-kB/IkB complex. Biochemical and Biophysical Research
Communications 260 691-698 Larsson P,
Claesson HE and Kennedy BP (1998) Multiple splice variants of the human
calcium-independent phospholipase A2 and their effect on enzyme activity.
Journal of Biological Chemistry 273 207-214 Larsson P, Ollinger K and Rosdahl I (2006) Ultraviolet (UV) A- and UVB-induced redox alterations and activation of nuclear factor-kB in human melanocytes-protective effects of alpha-tocopherol. British Journal of Dermatology 155 292-300 Larsson P, Ulfhammer E, Karlsson L, Bokarewa M, Wahlander K and Jern S (2008) Effects of IL-1beta and IL-6 on tissue-type plasminogen activator expression in vascular endothelial cells. Thrombosis Research in press Larter
CZ, Yeh MM< Cheng J, Williams J, Brown S, Dela Pena A, Bell-Anderson KS and
Farrell GC (2007) Activation of peroxisome proliferator-activated receptor
alpha by dietary fish oil attenuates steatosis, but does not prevent
experimental steatohepatitis because of hepatic lipoperoxide accumulation. Lasala C, Carre-Eusebe D, Picard JY and Rey R (2004) Subcellular and molecular mechanisms regulating anti-Mullerian hormone gene expression in mammalian and nonmammalian species. DNA Cell Biology 23 572-575 Lasarte JJ, Sarobe P, Boya P, Casares N, Arribillaga L, De Cerio AL, Gorraiz M, Borras-Cuesta F and Prieto J (2003) A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage. Hepatology 37 461-470 Laschke MW, Schwender C, Scheuer C, Vollmar B and Menger MD (2007) Dietary glycine does not affect physiological angiogenesis and reproductive function, but inhibits apoptosis in endometrial and ovarian tissue by down-regulation of nuclear factor-kB. Fertility and Sterility in press
Lasek W,
Switaj T, Sienko J, Kasprzycka M, Basak G, Miklaszewicz P, Maj M, Nowis D,
Grzela T, Golab J, Mlynarczuk I, Jalili A, Kaminska B, Dziembowska M,
Czajkowski K, Nowaczyk M, Gorska A and Kazimierczuk Z (2002) Stimulation of
TNF-a production by 2-(1-adamantylamino)-6-methylpyridine (AdAMP) - a novel
immunomodulator with potential application in tumour immunotherapy. Cancer
Chemotherapy and Pharmacology 50 213-222 Lash LH, Putt DA, Hueni SE and Horwitz BP (2005) Molecular markers of trichloroethylene-induced toxicity in human kidney cells. Toxicology and Applied Pharmacology 206 157-168 Lashmit PE, Lundquist CA, Meier JL and Stinski MF (2004) Cellular repressor inhibits human cytomegalovirus transcription from the UL127 promoter. Journal of Virology 78 5113-5123 Laska MJ, Strandbygard D, Kjeldgaard A, Mains M, Corydon TJ, Memon AA, Sorensen BS, Vogel U, Jensen UB and Nexo BA (2007) Expression of the RAI gene is conducive to apoptosis: Studies of induction and interference. Experimental Cell Research in press Laskin DL,
Fakhrzadeh L, Heck DE, Gerecke D and Laskin JD (2002) Upregulation of
phosphoinositide 3-kinase and protein kinase B in alveolar macrophages
following ozone inhalation. role of NF-kB and STAT-1 in ozone-induced nitric
oxide production and toxicity. Molecular and Cellular Biochemistry 234-235 91-98 Laskov R, Berger N and Horwitz MS (2005) Differential effects of tumor necrosis factor-alpha and CD40L on NF-kB inhibitory proteins IkappaBalpha, beta and varepsilon and on the induction of the Jun amino-terminal kinase pathway in Ramos Burkitt lymphoma cells. European Cytokine Network 16 267-276 Lass C, Vocanson M, Wagner S, Schempp CM, Nicolas JF, Merfort I and Martin SF (2008) Anti-inflammatory and immune-regulatory mechanisms prevent contact hypersensitivity to Arnica montana L. Experimental Dermatology in press Lassila O,
Vainio O, Toivanen P and Melchers F (1991) Doing the B-cell rag. New Biologist
3 1155-1160 Last JA, Gohil K, Mathrani VC and Kenyon NJ (2005) Systemic responses to inhaled ozone in mice: cachexia and down-regulation of liver xenobiotic metabolizing genes. Toxicology and Applied Pharmacology 208 117-126 Lasunskaia EB, Campos MN, de Andreade MR, Dammata RA, Kipnis TL, Einicker-Lamas M and Da Silva WD (2006) Mycobacteria directly induce cytoskeletal rearrangements for macrophage spreading and polarization through TLR2-dependent PI3K signaling. Journal of Leukocyte Biology 80 1480-1490 Laszlo CF and Wu S (2008) Mechanism of UV-induced IkBa-independent activation of NF-kB. Photochemistry & Photobiology in press Latchumanan VK, Singh B, Sharma P and Natarajan K (2002) Mycobacterium tuberculosis antigens induce the differentiation of dendritic cells from bone marrow. Journal of Immunology 169 6856-6564 Latimer M,
Ernst MK, Dunn LL, Drutskaya M and Rice NR (1998) The N-terminal domain of
IkBa masks the nuclear localization signal(s) of p50 and c-Rel homodimers.
Molecular and Cellular Biology 18 2640-2649 Latta M, Kunstle G, Lucas R, Hentze HM and Wendel A (2007) ATP-depleting carbohydrates prevent tumor necrosis factor receptor 1-dependent apoptotic and necrotic liver injury in mice. Journal of Pharmacology and Experimental Therapeutics in press Lattion A-L,
Espel E, Reichenbach P, Fromental C, Bucher P, Israël A, Baeuerle P, Rice NR
and Nabholz M (1992) Characterization of a new tissue-specific transcription
factor binding to the simian virus 40 enhancer TC-II (NF-kB) element.
Molecular and Cellular Biology 12 5217-5227 Latzer J,Papoian GA, Prentiss MC, Kmovies EA and Wolynes PG (2006) Induced fit, folding, and recognition of the NF-kB-nuclear localization signals by IkBa and IkBb. Journal of Molecular Biology in press Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA and Rahme LG (2003) The Drosophila melanogaster Toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa. Infection and Immunity 71 4059-4066 Lau PP, Li L, Merched AJ, Zhang AL, Ko KW and Chan L (2005) Nicotine induces proinflammatory responses in macrophages and the aorta leading to acceleration of atherosclerosis in low-density lipoprotein receptor-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology 26 143-149
Lauder A,
Castellanos A and Weston K (2001) c-Myb transcription is activated by protein
kinase B (PKB) following interleukin 2 stimulation of T cells and is required
for PKB-mediated protection from apoptosis. Molecular and Cellular Biology 21
5797-5805 Lauder SN, Carty SM, Carpenter CE, Hill RJ, Talamas F, Bondeson J, Brennan P and Williams AS (2007) Interleukin-1beta induced activation of nuclear factor-kb can be inhibited by novel pharmacological agents in osteoarthritis. Rheumatology (Oxford) in press Laughlin TM,
Bethea JR, Yezierski RP and Wilcox GL (2000) Cytokine involvement in dynorphin-induced
allodynia. Pain 84 159-167 Laura M, Mazzeo A, Aguennouz M, Santoro M, Catania MA, Migliorato A, Calapai G and Vita G (2006) Immunolocalization and activation of nuclear factor-kB in the sciatic nerves of rats with experimental autoimmune neuritis. Journal of Neuroimmunology 174 32-38 Laurencikiene J, van Harmelen V, Arvidsson Nordstrom E, Dicker A, Blomqvist L, Naslund E, Langin D, Arner P and Ryden M (2007) NF-kB is important for TNF-a-induced lipolysis in human adipocytes. Journal of Lipid Research in press Laurent S,
Otsuka M, De Saeger C, Maiter D, Lambotte L and Horsmans Y (2001) Expression
of presumed specific early and late factors associated with liver regeneration
in different rat surgical models. Lab Invest 81 1299-1307 Laurent S, Starkel P, Leclercq IA, Lambotte L, Maiter D and Horsmans Y (2005) Molecular events associated with accelerated proliferative response in rat livers when partial hepatectomy is preceded by a sham operation. European Journal of Clinical Investigation 35 140-147 Lauret C (2003) Medicinal Chemistry--First Anglo-Swedish Symposium. 23-26 March, 2003, Are Fjallby, Sweden. IDrugs 6 426-428 Laurent
S, Horsmans Y, Starkel P, Leclercq I, Sempoux C and Lambotte L (2005)
Disrupted NF-kB activation after partial hepatectomy does not impair
hepatocyte proliferation in rats. Laurent-Puig P and Taieb J (2008) Lessons from Tarceva in pancreatic cancer: where are we now, and how should future trials be designed in pancreatic cancer? Current Opinions in Oncology 20 454-458 Laurin N,
Brown JP, Morissette J and Raymond V (2002) Recurrent mutation of the gene
encoding sequestosome 1 (SQSTM1/p62) in Paget Disease of bone. American
Journal of Human Genetics 70 1582-1588 Lauzurica P,
Martinez-Martinez S, Marazuela M, Gomez del Arco P, Martinez C, Sanchez-Madrid
F and Redondo JM (1999) Pyrrolidine dithiocarbamate protects mice from lethal
shock induced by LPS or TNF-a. European Journal of Immunology 26 1890-1900 Lavagna C, Burgaud JL, Del Soldato P and Rampal P (2001) Antiproliferative effects of nitrosulindac on human colon adenocarcinoma cell lines. Biochemical and Biophysical Research Communications 284 808-816 Lavagno L, Gunella G, Bardelli C, Spina S, Fresu LG, Viano I and Brunelleschi S (2004) Anti-inflammatory drugs and tumor necrosis factor-alpha production from monocytes: role of transcription factor NF-kB and implication for rheumatoid arthritis therapy. European Journal of Pharmacology 501 199-208 Laval SH and Bushby KM (2004) Limb-girdle muscular dystrophies - from genetics to molecular pathology. Neuropathology and Applied Neurobiology 30 91-105 Lavallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK and Arai M (2006) Protein kinase C zeta zeta is upregulated in osteoarthritic cartilage and is required for activation of NF-kB by TNF and IL-1 in articular chondrocytes. Journal of Biological Chemistry 281 24124-24137 Lavie J,
Dandre F, Louis H, Lamaziere JM and Bonnet J (1999) Vascular cell adhesion
molecule-1 gene expression during human smooth muscle cell differentiation is
independent of NF-kB activation. Journal of Biological Chemistry 274 2308-2314 Lavie L (2003) Obstructive sleep apnoea syndrome - an oxidative stress disorder. Sleep Med Rev 7 35-51 Lavon I, Fuchs Zrihan D, Efroni G, Zelikovitch B, Fellig Y and Siegal T (2007) Novel mechanism whereby nuclear factor kB mediates DNA damage repair through regulation of O6-methylguanine-DNA-methyltransferase. Cancer Research 67 8952-8959 Lavon I,
Goldberg I, Amit S, Landsman L, Jung S, Tsuberi BZ, Barshack I, Kopolovic J,
Galun E, Bujard H and Ben-Neriah Y (2000) High susceptibility to bacterial
infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kB
activation. Nature Medicine 6 573-577 Lavon I, Pikarsky E, Gutkovich E, Goldberg I, Bar J, Oren M and Ben-Neriah Y (2003) Nuclear factor-kB protects the liver against genotoxic stress and functions independently of p53. Cancer Research 63 25-30 Law AH, Lee Dc, Cheung BK, Yim HC and Lau AS (2006) A role for the non-structural protein-1 of SARS-Coronavirus in chemokine dysregulation. Journal of Virology in press
Law RE,
Stimmel JB, Damore MA, Carter C, Clarke S and Wall R (1992)
Lipopolysaccharide-induced NF-kB activation in mouse 70Z/3 pre-B lymphocytes
is inhibited by mevinolin and 5'-methylthioadenosine: roles of protein
isoprenylation and carboxyl methylation reactions. Molecular and Cellular
Biology 12 103-111 Lawless MW, Greene CM, Mulgrew A, Taggart CC, O'Neill SJ and McElvaney NG (2004) Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha1-antitrypsin deficiency. Journal of Immunology 172 5722-5726
Lawlor KE,
Campbell IK, O'Donnell K, Wu L and Wicks IP (2001) Molecular and cellular
mediators of interleukin-1-dependent acute inflammatory arthritis. Arthritis
& Rheumatism 44 442-450 Lawrance IC, Wu F, Leite AZ, Willis J, West GA, Fiocchi C and Chakravarti S (2003) A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kB. Gastroenterology 125 1750-1761 Lawrence CP, Kadioglu A, Yang AL, Coward WR and Chow SC (2006) The cathepsin B inhibitor, z-FA-FMK, inhibits human T cell proliferation in vitro and modulates host response to Pneumococcal infection in vivo. Journal of Immunology 177 3827-3836 Lawrence DM, Seth P, Durham L, Diaz F, Boursiquot R, Ransohoff RM and Major EO (2006) Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells. Glia 53 81-91 Lawrence DM, Singh RS, Franklin DP, Carey DJ and Elmore JR (2004) Rapamycin suppresses experimental aortic aneurysm growth. Journal of Vascular Surgery 40 334-338 Lawrence R,
Chang L-J, Siebenlist U, Bressler P and Sonenshein GE (1994) Vascular smooth
muscle cells express a constitutive NF-kB-like activity. Journal of Biological
Chemistry 269 28913-28918 Lawrence T
(2002) Modulation of inflammation in vivo through induction of the heat shock
response, effects on NF-kB activation. Inflammation Research 51 108-109 Lawrence T, Bebien M, Liu GY, Nizet V and Karin M (2005) IKKa limits
macrophage NF-kB activation and contributes to the resolution of inflammation.
Nature 434 1138-1143 Lawrence T, Puel A, Reichenbach J, Ku CL, Chapgier A, Renner E, Minard-Colin V, Ouachee M and Casanova JL (2005) Autosomal-dominant primary immunodeficiencies. Current Opinion in Hematology 12 22-30 Lawson BR, Manenkova Y, Ahamed J, Chen X, Zou JP, Baccala R, Theofilopoulos AN and Yuan C (2007) Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system. Journal of Immunology 178 5366-5274 Lawson C,
Ainsworth M, Yacoub M and Rose M (1999) Ligation of ICAM-1 on endothelial
cells leads to expression of VCAM-1 via a nuclear factor-kB-independent
mechanism. Journal of Immunology 162 2990-2996 Laxmanan S, Datta D, Geehan C, Briscoe DM, and Pal S (2005) CD40: a mediator of pro- and anti-inflammatory signals in renal tubular epithelial cells. Journal of the American Society of Nephrology 16 2714-2723 Lay JD, Hong CC, Huang JS, Yang YY, Pao CY, Lin CH, Lai YP, Lai GM, Cheng AL, Su IJ and Chuang SE (2007) Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL. Cancer Research 67 3878-3887 Laye S, Lundkvist J and Bartfai T (1998) Human/mouse interleukin-1 receptor/receptor accessory protein interactions in IL-1beta-induced NFkB activation. FEBS Letters 429 307-311 Layfield R (2007) The molecular pathogenesis of Paget disease of bone. Expert Reviews in Molecular Medcine 9 1-13 Layfield R, Cavey MR, Najat D, Long J, Sheppard PW, Ralston SH and Searle MS (2006) p62 mutations, ubiquitin recognition and Paget's disease of bone. Biochemical Society Transactiions 34 735-737 Layfield R and Searle MS (2008) Disruption of ubiquitin-mediated processes in diseases of the brain and bone. Biochemical Society Transactions 36 469-471 Layfield R and Shaw B (2007) Ubiquitin-mediated signalling and Paget's disease of bone. BMC Biochemistry 8 S5 Laza-Stanca V, Stanciu LA, Message SD, Edwards MR, Gern JE and Johnston SL (2006) Rhinovirus replication in human macrophages induces NF-kB-dependent tumor necrosis factor alpha production. Journal of Virology 80 8248-8258 Lazaar AL,
Amrani Y, Hsu J, Panettieri Jr RA, Fanslow WC, Albelda SM and Pure E (1998)
CD40-mediated signal transduction in human airway smooth muscle. Journal of
Immunology 161 3120-3127 Lazarov M, Green CL, Zhang JY, Kubo Y, Dajee M and Khavari PA (2003) Escaping G(1) Restraints on neoplasia: Cdk4 regulation by Ras and NF-kB. Cell Cycle 2 79-80 Lazzerini PE, Lorenzini S, Selvi E, Capecchi PL, Chindamo D, Bisogno S, Ghittoni R, Natale MR, Caporali F, Giutini S, Marcolaongo R, Galeazzi M and Laghi-Pasini F (2007) Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. Clinical and Experimental Rheumatology 25 696-700 Le VT, Trilling M, Zimmermann A and Hengel H (2008) Mouse cytomegalovirus inhibits beta interferon (IFN-beta) gene expression and controls activation pathways of the IFN-beta enhanceosome. Journal of General Virology 89 1131-1141 Le Y, Iribarren P, Gong W, Cui Y, Zhang X, Wang JM (2004) TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways. Journal of Immunology 173 962-968
Le Bail O,
Schmidt-Ullrich and Israël A (1993) Promoter analysis of the gene encoding
the IkBa/MAD3 inhibitor of NF-kB: positive regulation by members of the
rel/NF-kB family. EMBO Journal 12 5043-5049 Le Beau MM,
Ito C, Cogswell P, Espinosa III R, Fernald AA and Baldwin Jr AS (1992)
Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kB
(NFKB2) and the IkB/MAD-3 (NFKBI) inhibitor of NF-kB to 4q24 and 14q13,
respectively. Genomics 14 529-531 Le Bon A, Montoya M, Edwards MJ, Thompson C, Bruke SA, Ashton M, Lo D, Tough DF and Borrow P (2006) A role for the transcription factor RelB in IFN-a production and in IFN-a-stimulated cross-priming. European Journal of Immunology in press Le Bras M, Rouy I and Brenner C (2006) The modulation of inter-organelle cross-talk to control apoptosis. Medicinal Chemistry 2 1-12 Le Clorennec C, Ouk TS, Youlyouz-Marfak I, Panteix S, Martin CC, Rastelli J, Adriaenssens E, Zimber-Strobl U, Coll J, Feullard J and Jayat-Vignoles C (2008) Molecular basis of Epstein-Barr virus latent membrane protein 1 (LMP1) cytotoxicity in EBV latency III B-cells: LMP1 induces type II ligand independent autoactivation of CD95/Fas with Caspase-8 mediated apoptosis. Journal of Virology in press Le Clorennec C, Youlyouz-Marfak I, Adriaenssens E, Coll J, Bornkamm GW and Feuillard J (2006) EBV Latency III immortalization program sensitizes B-cells to induction of CD95 mediated apoptosis via LMP1: role of NF-kB, STAT1 and p53. Blood 107 2070-2078 Le Mandat Schultz A, Bonnard A, Barreau F, Aigrain Y, Pierre-Louis C, Berrebi D and Peuchmaur M (2007) Expression of TLR-2, TLR-4, NOD2 and NF-kB in a neonatal rat model of necrotizing enterocolitis. PLoS ONE 2 e1102 Le Negrate G, Faustin B, Welsh K, Loeffler M, Krajewska M, Hasegawa P, Mukherjee S, Orth K, Krajewski S, Godzik A, Guiney DG and Reed JC (2008) Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kB, suppresses IkBa ubiquitination and modulates innate immune responses. Journal of Immunology 180 5045-5056 Le Negrate G, Krieg A, Faustin B, Loeffler M, Godzik A, Krajewski S and Reed JC (2008) ChlaDub1 of Chlamydia trachomatis suppresses NF-kB activation and inhibits IkBa ubiquitination and degradation. Cellular Microbiology in press Le Page C, Koumakpayi IH, Lessard L, Mes-Masson AM and Saad F (2005) EGFR and Her-2 regulate the constitutive activation of NF-kB in PC-3 prostate cancer cells. Prostate 65 306-315 Le Page C, Koumakpayi IH, Lessard L, Saad F and Mes-Masson AM (2005) Independent role of phosphoinositol-3-kinase (PI3K) and casein kinase II (CK-2) in EGFR and Her-2-mediated constitutive NF-kB activation in prostate cancer cells. Prostate in press Le Page C,
Popescu O, Genin P, Lian J, Paquin A, Galipeau J and Hiscott J (2001)
Disruption of NF-kB signaling and chemokine gene activation by retroviral
mediated expression of IKKg/NEMO mutants. Virology 286 422-433 Le Page C,
Sanceau J, Drapier JC and Wietzerbin J (1998) Inhibitors of ADP-ribosylation
impair inducible nitric oxide synthase gene transcription through inhibition
of NF kappa B activation. Biochemical and Biophysical Research Communications
243 451-457 Le Page C and Wietzerbin J (2003) Modulation of the activation of extracellular signal-regulated kinase (ERK) and the production of inflammatory mediators by ADP-ribosylation inhibitors. Biol Chem 384 1509-1513 Le Tulzo Y,
Shenkar R, Kaneko D, Moine P, Fantuzzi G, Dinarello CA and Abraham E (1997)
Hemorrhage increases cytokine expression in lung mononuclear cells in mice:
involvement of catecholamines in Nuclear Factor-kB regulation and cytokine
expression. Journal of Clinical Investigation 99 1516-1524 Lean J, Kirstein B, Urry Z, Chambers T and Fuller K (2004) Thioredoxin-1 mediates osteoclast stimulation by reactive oxygen species. Biochemical and Biophysical Research Communications 321 845-850 Lean JM, Davies JT, Fuller K, Jagger CJ, Kirstein B, Partington GA, Urry ZL and Chambers TJ (2003) A crucial role for thiol antioxidants in estrogen-deficiency bone loss. Journal of Clinical Investigation 112 915-923 Leban J, Baierl M, Mies J, Trentinaglia V, Rath S, Kronthaler K, Wolf K, Gotschlich A and Seifer MH (2007) A novel class of potent NF-kB signaling inhibitors. Bioorganic & Medicinal Chemistry Letters in press Leblanc PM, Yertssian G, Rutherford N, Doiron K, Nadiri A, Zhu L, Green DR, Gruenheid S and Saleh M (2008) Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity. Cell Host Microbe 3 146-157 LeBlanc R, Hideshima T, Catley LP, Shringarpure R, Burger R, Mitsiades N, Mitsiades C, Cheema P, Chauhan D, Richardson PG, Anderson KC and Munshi NC (2004) Immunomodulatory drug co-stimulates T cells via the B7-CD28 pathway. Blood 103 1787-1790 Leblanc V, Dery MC, Shooner C and Asselin E (2003) Opposite regulation of XIAP and Smac/DIABLO in the rat endometrium in response to 17beta-estradiol at estrus. Reprod Biol Endocrinol 1 59 Lebovic DI,
Chao VA, Martini JF and Taylor RN (2001) IL-1beta induction of RANTES
(regulated upon activation, normal T cell expressed and secreted) chemokine
gene expression in endometriotic stromal cells depends on a nuclear factor-kB
site in the proximal promoter. Journal of Clinical Endocrinology and Metabolism 86 4759-4764 Lebowitz J, Edinger RS, An B, Perry CJ, Onate S, Kleyman TR and Johnson JP (2004) IKKbeta modulation of epithelium sodium channel activity. Journal of Biological Chemistry 279 41985-41990 Lebron F, Vassallo R, Puri V and Limper AH (2003) Pneumocystis carinii cell wall beta-glucans initiate macrophage inflammatory responses through NF-kB activation. Journal of Biological Chemistry 278 25001-25008
Lebruska LL
and Maher LJ, 3rd (1999) Selection and characterization of an RNA decoy for
transcription factor NF-kB. Biochemistry 38 3168-3174 Lecain E, Omri B, Behar-Cohen F, Tran Ba Huy P and Crisanti P (2007) The role of PKCzeta in amikacin-induced apoptosis in the cochlea: Prevention by aspirin. Apoptosis 12 333-342 Lecine P, Esmiol S, Metais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP and Ollendorff V (2007) The NOD2-RICK complex signals from the plasma membrane. Journal of Biological Chemistry in press LeClair KP,
Blanar MA and Sharp PA (1992) The p50 subunit of NF-kB associates with the
NF-IL6 transcription factor. Proceedings of the National Academy of Sciences
USA 89 8145-8149 Leclercq IA, Farrell GC, Sempoux C, Pena AD and Horsmans Y (2004) Curcumin inhibits NF-kB activation and reduces the severity of experimental steatohepatitis in mice. Journal of Hepatology 41 926-934 Leclercq IA, Field J and Farrell GC (2003) Leptin-specific mechanisms for impaired liver regeneration in ob/ob mice after toxic injury. Gastroenterology 124 1451-1464 Lecureur V, Ferrec EL, N'diaye M, Vee ML, Gardyn C, Gilot D and Fardel O (2005) ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages. FEBS Letters 579 1904-1910 Ledeboer A, Gamanos M, Lai W, Martin D, Maier SF, Watkins LR and Quan N (2005) Involvement of spinal cord nuclear factor kB activation in rat models of proinflammatory cytokine-mediated pain facilitation. European Journal of Neuroscience 22 1977-1986 Ledebur HC
and Parks TP (1995) Transcriptional regulation of the intercellular adhesion
molecule-1 gene by inflammatory cytokines in human endothelial cells.
Essential roles of a variant NF-kB site and p65 homodimers. Journal of
Biological Chemistry 270 933-943 Lederer JA,
Liou JS, Kim S, Rice N and Lichtman AH (1996) Regulation of NF-kB activation
in T helper 1 and T helper 2 cells. Journal of Immunology 156 56-63 Ledoux S, Yang R, Friedlander G and Laouari D (2003) Glucose depletion enhances p-glycoprotein expression in hepatoma cells: role of endoplasmic reticulum stress response. Cancer Research 63 7284-7290 Lee AK, Sung SH, Kim YC and Kim SG (2003) Inhibition of lipopolysaccharide-inducible nitric oxide synthase, TNF-alpha and COX-2 expression by sauchinone effects on I-kBa phosphorylation, C/EBP and AP-1 activation. British Journal of Pharmacology 139 11-20 Lee B and Moon SK (2005) Resveratrol inhibits TNF-a-induced proliferation and matrix metalloproteinase expression in human vascular smooth muscle cells. Journal of Nutrition 135 2767-2773
Lee B, Park
S, Kang K, Park R and Kim I (2002) NF-kB activates fibronectin gene expression
in rat hepatocytes. Biochemical and Biophysical Research Communications 297
1218 Lee BC, Kim SH, Choi SH and Kim TS (2005) Induction of interleukin-8 production via nuclear factor-kB activation in human intestinal epithelial cells infected with Vibrio vulnificus. Immunology 115 506-515 Lee BH, Kim
MS, Rhew JH, Park RW, de Crombrugghe B and Kim IS (2000) Transcriptional
regulation of fibronectin gene by phorbol myristate acetate in hepatoma cells:
a negative role for NF-kB. Journal of Cellular Biochemistry 76 437-451 Lee BH and Ruoslahti E (2005) alpha(5)beta(1) integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca(2+)/calmodulin-dependent protein kinase IV. Journal of Cellular Biochemistry 95 1214-1223 Lee BL, Lee HS, Jung J, Cho SJ, Chung HY, Kim WH, Jin YW, Kim CS and Nam SY (2005) Nuclear factor kB activation correlates with better prognosis and Akt activation in human gastric cancer. Clinical Cancer Research 11 2518-2525 Lee BN, Dantzer R, Langley KE, Bennett GJ, Dougherty PM, Dunn AJ, Meyers CA, Miller AH, Payne R, Reuben JM, Wang XS and Cleeland CS (2004) A cytokine-based neuroimmunologic mechanism of cancer-related symptoms. Neuroimmodulation 11 279-292 Lee BS, Heo J, Kim YM, Shim SM, Pae HO, Kim YM and Chung HT (2006) Carbon monoxide mediates heme oxygenase 1 induction via Nrf2 activation in hepatoma cells. Biochemical and Biophysical Research Communications 343 965-972 Lee BS,
Paulose-Murphy M, Chung YH, Connlole M, Zeichner S and Jung JU (2002)
Suppression of tetradecanoyl phorbol acetate-induced lytic reactivation of
Kaposi's Sarcoma-associated herpesvirus by K1 signal transduction. Journal of
Virology 76 12185-12199 Lee C,
Schwartz MP, Prakash S, Iwakura M and Matouschek A (2001) ATP-dependent
proteases degrade their substrates by processively unraveling them from the
degradation signal. Molecular Cell 7 627-637 Lee CC, Cheng YW and Kang JJ (2005) Motorcycle exhaust particles induce IL-8 production through NF-kB activation in human airway epithelial cells. Journal of Toxicology and Environmental Health A 68 1537-1555 Lee CH, Jeon YT, Kim SH and Song YS (2007) NF-kB as a potential molecular target for cancer therapy. Biofactors 29 19-35 Lee CH, Shieh DC, Tzeng CY, Chen CP, Wang SP, Chiu YC, Huang CY, Hsu CJ, Fong YC and Tang CH (2008) Bradykinin-induced IL-6 expression through bradykinin B2 receptor, phospholipase C, protein kinase Cdelta and NF-kB pathway in human synovial fibroblasts. Molecular Immunology in press Lee CJ, Lee SS, Chen SC, Ho FM and Lin WW (2005) Oregonin inhibits lipopolysaccharide-induced iNOS gene transcription and upregulates HO-1 expression in macrophages and microglia. British Journal of Pharmacology 146 378-388 Lee CK, Lee EY, Chung SM, Mun SH, Yoo B and Moon HB (2004) Effects of disease-modifying antirheumatic drugs and antiinflammatory cytokines on human osteoclastogenesis through interaction with receptor activator of nuclear factor kB, osteoprotegerin, and receptor activator of nuclear factor kB ligand. Arthritis and Rheumatism 50 3831-3843 Lee CK, Lee EY, Kim YG, Mun SH, Moon HB and Yoo B (0208) Alpha-lipoic acid inhibits TNF-alpha induced NF-kB activation through blocking of MEKK1-MKK4-IKK signaling cascades. Interntational Immunopharmacology 8 362-370 Lee CT, Seol JY, Lee SY, Park KH, Han SJ, Yoo CG, Han SK, Shim YS and Kim YW (2003) The effect of adenovirus-IkBa transduction on the chemosensitivity of lung cancer cell line with resistance to cis-diamminedichloroplatinum(II)(cisplatin) and doxorubicin(adriamycin). Lung Cancer 41 199-206 Lee CW, Lin CC, Lin WN, Liang KC, Luo SF, Wu CB, Wang SW and Yang CM (2006) TNF-a induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kB/p300 binding in human tracheal smooth muscle cells. American Journal of Physiology: Lung Cell and Molecular Physiology in press Lee CW, Lin WN, Lin CC, Luo SF, Wang JS, Pouyssegur J and Yang CM (2006) Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: Involvement of MAPKs, NF-kB, p300, and histone acetylation. Journal of Cellular Physiology 207 174-186 Lee CW, Lin CC< Luo SF, Lee HC, Lee IT, Aird WC, Hwang Tl and Yang CM (2008) TNF-a enhances neutrophil adhesiveness: Induction of VCAM-1 via activation of Akt and CaM kinase II and modification of HAT and HDAC4 in human tracheal smooth muscle cells. Molecular Pharmacology in press Lee DC, Cheung CY, Law AH, Mok CK, Peiris M and Lau AS (2005) p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1. Journal of Virology 79 10147-10154 Lee DH, Cho KS, Park SG, Kim EK and Joo CK (2005) Cellular death mediated by nuclear factor kB (NF-kB) translocation in cultured human lens epithelial cells after ultraviolet-B irradiation. J Cataract Refract Surg 31 614-619 Lee DH, Kim JK and Joo CK (2005) Translocation of nuclear factor-kB on corneal epithelial cells induced by ultraviolet B irradiation. Ophthalmic Research 37 83-88 Lee DH, Kim SH, Eun JS and Shin TY (2006) Mosla dianthera inhibits mast cell-mediated allergic reactions through the inhibition of histamine release and inflammatory cytokine production. Toxicology and Applied Pharmacology in press Lee DH,
Macintyre JP, Taylor GR, Wang E, Plante RK, Tam SS, Pope BL and Lau CY (1999)
Tepoxalin enhances the activity of an antioxidant, pyrrolidine
dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis
in WEHI 164 cells. Journal of Pharmacology and Experimental Therapeutics 289 1465-1471 Lee DH, Tam
SS, Wang E, Taylor GR, Plante RK and Lau CY (1996) The NF-kB inhibitor,
tepoxalin, suppresses surface expression of the cell adhesion molecules CD62E,
CD11b/CD18 and CD106. Immunology Letters 53 109-113 Lee DJ, Cox
D, Li J and Greenberg S (2000) Rac1 and Cdc42 are required for phagocytosis,
but not NF-kB-dependent gene expression, in macrophages challenged with
Pseudomonas aeruginosa. Journal of Biological Chemistry 275 141-146 Lee DK, Kang JE, Park HJ, Kim MH, Yim TH, Kim JM, Heo MK, Kim KY, Kwon HJ and Hur MW (2005) FBI-1 enhances transcription of NF-kB responsive E-selectin gene by nuclear localization of p65 subunit of NF-kB. Journal of Biological Chemistry 280 27783-27791 Lee EC and Tenniswood M (2004) Programmed cell death and survival pathways in prostate cancer cells. Annals of Andrology 50 27-32 Lee EG, Boone
DL, Chai S, Libby SL, Chein M, Lodolce JP and Ma A (2000) Failure to regulate
TNF-induced NF-kB and cell death responses in A20-deficient mice. Science 289
2351-2354 Lee EJ, Seo SR, Um JW, Park J, Oh Y and Chung KC (2008) NF-kB-inducing kinase phosphorylates and blocks the degradation of Down Syndrome candidate region 1. Journal of Biology Chemistry in press Lee ES, Ju HK, Moon TC, Lee E, Jahng Y, Lee SH, Son JK, Baek SH and Chang HW (2004) Inhibition of nitric oxide and tumor necrosis factor-alpha (TNF-alpha) production by propenone compound through blockade of nuclear factor (NF)-kB activation in cultured murine macrophages. Biol Pharm Bull 27 617-620 Lee ES, Kalantari P, Tsutsui Section S, Klatt A, Holden J, Correll PH, Power Section C and Henderson AJ (2004) RON receptor tyrosine kinase, a negative regulator of inflammation, inhibits HIV-1 transcription in monocytes/macrophages and is decreased in brain tissue from patients with AIDS. Journal of Immunology 173 6864-6872 Lee EY, Lee CK, Lee KU, Park JY, Cho KJ, Cho YS, Lee HR, Moon SH, Moon HB and Yoo B (2006) Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice. Rheumatology International in press Lee FS,
Hagler J, Chen ZJ and Maniatis T (1997) Activation of the IkBa kinase complex
by MEKK1, a kinase of the JNK pathway. Cell 88 213-222 Lee FS,
Peters RT, Dang LC and Maniatis T (1998) MEKK1 activates both IkB kinase a and
IkB kinase b. Proceedings of the National Academy of Sciences USA 95 9319-9324 Lee FT, Cao Z, Long DM, Panagiotopoulos S, Jerums G, Cooper ME and Forbes JM (2004) Interactions between angiotensin II and NF-kB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy. Journal of the American Society of Nephrology 15 2139-2151 Lee FY, Kim DW, Karmin JA, Hong D, Chang SS, Fujisawa M, Takayanagi H, Bigliani LU, Blaine TA and Lee HJ (2005) mu-calpain regulates RANKL-supported osteoclastogenesis via NF-kB activation in raw 264.7 cells. Journal of Biological Chemistry 280 29929-29936 Lee FY, Li Y,
Zhu H, Yang S, Lin HZ, Trush M and Diehl AM (1999) Tumor necrosis factor
increases mitochondrial oxidant production and induces expression of
uncoupling protein-2 in the regenerating mice [correction of rat] liver.
Hepatology 29 677-687 Lee G, Na HJ, Namkoong S, Kwon HJ, Han S, Ha KS, Kwon YG, Lee H and Kim YM (2006) 4-O-methylgallic acid down-regulates endothelial adhesion molecule expression by inhibiting NF-kB-DNA-binding activity. European Journal of Pharmacology in press Lee GC, Yi HA and Lee CH (2006) Stimulation of intereron-beta gene expression by human cytomegalovirus via nuclear factor kB and phosphatiylinosital 3-kinasse pathway. Virus Research 117 209-214 Lee GS, Choi KC, Han HJ and Jeung EB (2007) The classical and a non-classical pathways associated with NF-kB are involved in estrogen-medicated regulation of Calbindin-D9k gene in rat pituitary cells. Molecular and Cellular Endocrinology in press Lee GT, Ha H, Lee HC and Cho YD (2003) Agmatine reduces hydrogen peroxide in mesangial cells under high glucose conditions. Journal of Biochemistry and Molecular Biology 36 251-257 Lee H, Arsura
M, Wu M, Duyao M, Buckler AJ and Sonenshein GE (1995) Role of Rel-related
factors in control of c-myc gene transcription in receptor-mediated apoptosis
of the murine B cell WEHI 231 line. Journal of Experimental Medicine 181
1169-1177 Lee H, Choi
JK, Li M, Kaye K, Kieff E and Jung JU (1999) Role of cellular tumor necrosis
factor receptor-associated factors in NF-kB activation and lymphocyte
transformation by herpesvirus Saimiri STP. Journal of Virology 73 3913-3919 Lee H, Jeong J, Son E, Mosa A, Cho GJ, Choi WS, Ha JH, Kim IK, Lee MG, Kim CY and Suk K (2004) Ethanol selectively modulates inflammatory activation signaling of brain microglia. Journal of Neuroimmunology 156 88-95 Lee H, Kim YO, Kim H, Kim SY, Noh HS, Kang SS, Cho GJ, Choi WS and Suk K (2003) Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB Journal 17 1943-1944 Lee H, Kong SW and Park PJ (2008) Integrative analysis reveals the direct and indirect interactions between DNA copy number aberrations and gene expression changes. Bioinformatics in press Lee H, Lin CI, Liao JJ, Lee YW, Yang HY, Lee CY, Hsu HY and Wu HL (2004) Lysophospholipids increase ICAM-1 expression in human umbilical cord vein endothelial cells through a Gi- and NFkB-dependent mechanism. American Journal of Physiology: Cellular Physiology 287 C1657-C1666 Lee H, Park C,Cho IH,Kim HY, Jo EK, Lee S, Kho HS, Choi SY, Bae oh S, Park K, Kim JS and Lee SJ (2007) Double-stranded RNA induces iNOS gene expression in Schwann cells, sensory neuronal death, and peripheral nerve demyelination. Glia in press Lee H, Pespeni M, Roux J, Dennery PA, Matthay MA and Pittet JF (2004) HO-1 induction restores c-AMP-dependent lung epithelial fluid transport following severe hemorrhage in rats. FASEB Journal 19 287-289 Lee H and Suk K (2004) Selective modulation of microglial signal transduction by PACAP. Neuroreport 15 1469-1474 Lee H, Wu M,
La Rosa FA, Duyao MP, Buckler AJ and Sonenshein GE (1995) Role of Rel-family
of transcription factors in the regulation of c-myc gene transcription
and apoptosis of WEHI 231 murine B-cells. Current Topics in Microbiology and
Immunology 194 247-255 Lee HA and
Hughes DA (2001) Alpha-lipoic acid modulates NF-kB activity in human
monocytic cells by direct interaction with DNA. Experimental Gerontology 37
401-410 Lee HB, Yu MR, Yang Y, Jiang Z and Ha H (2003) Reactive oxygen species-regulated signaling pathways in diabetic nephropathy. American Journal of the American Society of Nephrology 14 S241-S245 Lee HC and Goodman JL (2006) Anaplasma phagocytophilum causes global induction of antiapoptosis in human neutrophils. Genomics 88 496-503 Lee HC and Ziegler SF (2007) Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkB. Proceedings of the National Academy of Sciences USA in press Lee HG, Kim H, Oh WK, Yu KA, Choe YK, Ahn JS, Kim DS, Kim SH, Dinarello CA, Kim K and Yoon DY (2004) Tetramethoxy hydroxyflavone p7F downregulates inflammatory mediators via the inhibition of nuclear factor kB. Annals of the New York Academy of Sciences 1030 555-568 Lee HJ, Lee DY, Joo WA, Sul D, Lee E and Kim CW (2004) Differential expression of proteins in rat plasma exposed to benzene. Proteomics 4 3498-3504 Lee HJ, Oh TH, Yoon WJ, Kang GJ, Yang EJ, Park SS, Lee NH, Kang HK and Yoo ES (2008) Eutigoside C inhibits the production of inflammatory mediators (NO, PGE(2), IL-6) by down-regulating NF-kB and MAP kinase activity in LPS-stimulated RAW 264.7 cells. Journal of Pharmacy and Pharmacology 60 917-924 Lee HH,
Dadgostar H, Cheng Q, Shu J and Cheng G (1999) NF-kB-mediated up-regulation of
Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes.
Proceedings of the National Academy of Sciences USA 96 9136-9141 Lee HH,
Dempsey PW, Parks TP, Zhu X, Baltimore D and Cheng G (1999) Specificities of
CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and
intercellular adhesion molecule-1 up-regulation. Proceedings of the National
Academy of Sciences USA 96 1421-1426 Lee HH, Shiow
SJ, Chung HC, Huang CY, Lin CL, Hsu JD, Shyu LY and Wang CJ (2000) Development of
brain injury in mice by Angiostrongylus cantonensis infection is associated
with the induction of transcription factor NF-kB, nuclear protooncogenes, and
protein tyrosine phosphorylation. Experimental Parasitology 95 202-208 Lee HJ, Cho JW, Kim SC, Kang KH, Lee SK, Pi SH, Lee SK and Kim EC (2006) Roles of p38 and ERK MAP kinases in IL-8 expression in TNF-a- and dexamethasone-stimulated human periodontal ligament cells. Cytokine 35 67-76 Lee HJ, Jeong HS, Kim DJ, Noh YH, Yuk DY and Hong JT (2008) Inhibitory effect of citral on NO production by suppression of iNOS expression and NF-kB activation in RAW264.7 cells. Archives of Pharmacal Research 31 342-349 Lee HJ, Lee J, Lee SK, Lee SK and Kim EC (2007) Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kB in immortalized and malignant oral keratinocytes. BMC Cancer 7 176 Lee HJ, Lee J, Min SK, Guo HY, Lee SK, Kim HR, Pae HO, Chung HT, Hong SH, Lee SK and Kim EC (2008) Differential induction of heme oxygenase-1 against nicotine-induced cytotoxicity via the PI3K, MAPK, and NF-kB pathways in immortalized and malignant human oral keratinocytes. Journal of Oral Pathology and Medicine in press Lee HJ, Oh YK, Rhee M, Lim JY, Hwang JY, Park YS, Kwon Y, Choi KH, Jo I, Park SJ, Gao B and Kim WH (2007) The role of STAT1/IRF-1 on synergistic ROS production and loss of mitochondrial transmembrane potential during hepatic cell death induced by LPS/d-GalN. Jounral of Molecular Biology in press Lee HK, Lee J
and Tobias PS (2002) Two lipoproteins extracted from Escherichia coli K-12
LCD25 lipopolysaccharide are the major components responsible for Toll-like
receptor 2-mediated signaling. Journal of Immunology 168 4012-4017 Lee HO, Lee JH, Kim TY and Lee H (2007) Regulation of DeltaNp63alpha by tumor necrosis factor-alpha in epithelial homeostasis. FEBS Journal in press Lee HR, Cheong HJ, Kim SJ, Lee NS, Park HS and Won JH (2008) Sulindac enhances arsenic trioxide-mediated apoptosis by inhibition of NF-kB in HCT116 colon cancer cells. Oncology Reports 20 41-47 Lee HS, Chang JS, Baek JA, Chung MY, Lee HC, Rhim BY, Sok DE, Rho MC, Kim YK and Kim K (2005) TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol. Biochemical and Biophysical Research Communications 333 1093-1099 Lee HS, Choi CY, Cho C and Song Y (2003) Attenuating effect of Chlorella supplementation on oxidative stress and NFkB activation in peritoneal macrophages and liver of C57BL/6 mice fed on an atherogenic diet. Biosci Biotechnol Biochem 67 2083-2090 Lee HS, Kim HJ, Moon CS, Chong YH and Kang JL (2004) Inhibition of c-Jun NH2-terminal kinase or extracellular signal-regulated kinase improves lung injury. Respiration Research 5 23 Lee HS, Lee CH, Tsai HC and Salter DM (2008) Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1b. Osteoarthitis and Cartilage in press Lee HS, Moon C, Lee HW, Park EM, Cho MS and Kang JL (2007) Src tyrosine kinases mediate activations of NF-kB and integrin signal during lipopolysaccharide-induced acute lung injury. Journal of Immunology 179 7001-7011 Lee HT, Chen SW, Doetschman TC, Deng C, D'Agati VD and Kim M (2008) Sevoflurane protects against renal ischemia and reperfusion injury in mice via the transforming growth factor-beta1 pathway. American Journal of Physiology: Renal Physiology in press Lee HT, Ota-Setlik A, Fu Y, Nasr SH and Emala CW (2004) Differential protective effects of volatile anesthetics against renal ischemia-reperfusion injury in vivo. Anesthesiology 101 1313-1324 Lee HT, Kim M, Jan M and Emala CW (2006) Anti-inflammatory and anti-necrotic effects of the volatile anesthetic sevoflurane in kidney proximal tubule cells. American Journal of Physiology: Renal Physiology 291 F67-F78 Lee HW, Ahn
DH, Crawley SC, Li JD, Gum JR Jr, Basbaum CB, Fan NQ, Szymkowski DE, Han SY,
Lee BH, Sleisenger MH and Kim YS (2002) Phorbol 12-myristate 13-acetate
up-regulates the transcription of MUC2 intestinal mucin via Ras, ERK, and
NF-kB. Journal of Biolgoical Chemistry 277 32624-32631 Lee HW, Kim BS, Kim HJ, Lee CW, Yoo HJ, Kim JB and Yoon S (2005) Upregulation of receptor activator of nuclear factor-kappaB ligand expression in the thymic subcapsular, paraseptal, perivascular, and medullary epithelial cells during thymus regeneration. Histochemistry and Cell Biology 123 491-5400 Lee HW, Park
SJ, Choi BK, Kim HH, Nam KO and Kwon BS (2002) 4-1BB promotes the survival of
CD8(+) T lymphocytes by increasing expression of Bcl-x(L) and Bfl-1. Journal
of Immunology 169 4882-4888 Lee HW, Park HK, Na YJ, Kim CD, Lee JH, Kim BS, Kim JB, Lee CW, Moon JO and Yoon S (2008) RANKL stimulates proliferation, adhesion and IL-7 expression of thymic epithelial cells. Experimental Molecular Medicine 40 59-70 Lee HY, Jeon HS, Song EK, Han MK, Park SL, Lee SI, Yun HJ, Kim JR, Kim JS, Lee YC, Kim SI, Kim HR, Choi JY, Kang I, Kim HY and Yoo WH (2006) CD40 ligation of rheumatoid synovial fibroblasts regulates RANKL-medicated osteoclastogenesis: Evidence of NF-kB-dependent, CD40-mediated bone destruction in rheumatoid arthritis. Arthritis and Rheumatism 54 1747-1758 Lee HY, Kim MK, Park KS, Bae YH, Yun J, Park JI, Kwak JY and Bae YS (2005) Serum amyloid A stimulates matrix-metalloproteinase-9 upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells. Biochemical and Biophysical Research Communications 330 989-998 Lee HY, Park KS, Kim MK, Lee T, Ryun SH, Woo KJ, Kwon TK and Bae YS (2005) A small compound that inhibits tumor necrosis factor-alpha-induced matrix metalloproteinase-9 upregulation. Biochemical and Biophsyical Research Communications in press Lee HY, Youn SW, Kim JY, Park KW, Hwang CI, Park WY, Oh BH, Park YB, Walsh K, Seo JS and Kim HS (2007) FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kB. Arteriosclerosis, Thrombosis, and Vascular Biology in press Lee I, Kim
MK, Choi EY, Mehl A, Jung KC, Gil MC, Rowe M and Park SH (2001) CD99
expression is positively regulated by Sp1 and is negatively regulated by
Epstein-Barr virus latent membrane protein 1 through nuclear factor-kB. Blood
97 3596-3604 Lee IO, Lee KH, Pyo JH, Kim JH, Choi YJ and Lee YC (2007) Anti-inflammatory effect of capsaicin in Helicobacter pylori-infected gastric epithelial cells. Helicobacter 12 510-517 Lee IS, Kim SH, Song HG and Park SH (2003) The molecular basis for the generation of Hodgkin and Reed-Sternberg cells in Hodgkin's lymphoma. International Journal of Hematology 77 330-335
Lee IS, Shin
YK, Chung DH and Park SH (2001) LMP1-induced downregulation of CD99 molecules
in Hodgkin and Reed-Sternberg cells. Leukemia and Lymphoma 42
587-594 Lee J, Chuang TH, Redecke V, She L, Pitha PM, Carson DA, Raz E and Cottam HB (2003) Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7. Proceedings of the National Academy of Sciences USA 100 6646-6651 Lee J, Ho WH, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI and Gurney AL (2001) IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. Journal of Biological Chemistry 276 1660-1664 Lee J, Im YH, Jung HH, Kim JH, Park JO, Kim K, Kim WS, Ahn JS, Jung CW, Park YS, Kang WK and Park K (2005) Curcumin inhibits interferon-alpha induced NF-kB and COX-2 in human A549 non-small cell lung cancer cells. Biochemical and Biophysical Research Communications 334 313-318 Lee J, Jung E, Kim Y, Lee J, Park J, Hong S, Hyun CG, Park D and Kim YS (2006) Rosmarinic acid as a downstream inhibitor of IKK-b in TNF-a-induced upregulation of CCL11 and CCR3. British Journal of Pharmacology 148 366-375 Lee J, Jung E, Lim J, Lee J, Hur S, Kim SS, Lim S, Hyun CG, Kim YS and Park D (2006) Involvement of nuclear factor-kB in the inhibition of pro-inflammatory mediators by pinosylvin. Planta Medica in press
Lee J, Jung E, Park J, Jung K, Lee S, Hong S, Park J, Park E, Kim J, Park S
and Park D (2005) Anti-inflammatory effects of magnolol and honokiol are
mediated through inhibition of the downstream pathway of MEKK-1 in NF-kB
activation signaling. Planta
Med 71 338-343 Lee J, Jung E, Park B, Jung K, Park J, Kim K, Kim KH and Park D (2005) Evaluation of the anti-inflammatory and atopic dermatitis-mitigating effects of BSASM, a multicompound preparation. Journal of Ethnopharmacology 96 211-219 Lee J, Jung E, Park J and Park D (2005) Transdermal delivery of interferon gamma (IFN gamma) mediated by penetratin, a cell-permeable peptide. Biotechnology and Applied Biochemistry 42 169-173 Lee J, Jung KD, Park CG, Han JW and Lee HY (2006) Autotaxin stimulates urokinase-type plasminogen activator expression through phosphoinositide 3-kinase-Akt-necrosis factor kB signaling cascade in human melanoma cells. Melanoma Research 16 445-452 Lee J, Kim MS, Kim EY, Park HJ, Chang CY, Park KS, Jung DY, Kwon CH, Joh JW and Kim SJ (2008) Mycophenolate mofetil promotes down-regulation of expanded B cells and production of TNF-a in an experimental murine model of colitis. Cytokine in press Lee J, Kim YS, Choi DH, Bang MS, Han TR, Joe TH and Kim SY (2004) Transglutaminase 2 induces NF-kB activation via a novel pathway in BV-2 microglia. Journal of Biological Chemistry 279 53725-53735 Lee J, Mo JH, Katakura K, Alkalay I, Rucker AN, Liu YT, Lee HK, Shen C, Cojocaru G, Shenouda S, Kagnoff M, Eckmann L, Ben-Neriah Y and Raz E (2006) Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nature Cell Biology 8 1327-1336 Lee J, Mo JH, Shen C, Rucker AN and Raz E (2007) Toll-like receptor signaling in intestinal epithelial cells contributes to colonic homoeostasis. Current Opinion in Gastroenterology 23 27-31 Lee J, Seo J, Kim H, Chung JB and Kim KH (2003) Signal transduction of cerulein-induced cytokine expression and apoptosis in pancreatic acinar cells. Annals of the New York Academy of Sciences 1010 104-108 Lee J, Shin S, Teng CH, Hong SJ and Kim KS (2005) FimH adhesin of Escherichia coli K1 type 1 fimbriae activates BV-2 microglia. Biochemical and Biophysical Research Communications 334 917-923 Lee J and Sugden B (2007) A membrane leucine heptad contributes to LMP1's trafficking, signaling and transformation. Journal of Virology in press Lee JA, Hwang JA, Sung HN, Jeon CH, Gill BC, Youn HJ and Park JH (2007) 2,3,7,8-tetrachlorodibenzo-p-dioxin modulates functional differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicological Letters in press Lee JC, Kim J, Park JK, Chung GH and Jang YS (2003) The antioxidant, rather than prooxidant, activities of quercetin on normal cells: quercetin protects mouse thymocytes from glucose oxidase-mediated apoptosis. Experimental Cell Research 291 386-397 Lee JC, Kundu JK, Hwang DM, Na HK and Surh YJ (2007) Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kB and AP-1: IkB kinase and c-Jun-N-terminal kinase as respective potential upstream targets. Carcinogenesis 1491-1498 Lee JC, Lee KY, Son YO, Choi KC, Kim J, Truong TT and Jang YS (2005) Plant-originated glycoprotein, G-120, inhibits the growth of MCF-7 cells and induces their apoptosis. Food Chem Toxicol 43 961-968 Lee JC, Won SJ, Chao CL, Wu FL, Liu HS, Ling P, LIn CN and Su CL (2008) Morusin induces apoptosis and suppresses NF-kB activity in human colorectal cancer HT-29 cells. Biochemical and Biophysical Research Communications in press Lee JE, Shin HH, Lee EA, Van Phan T and Choi HS (2007) Stimulation of osteoclastogenesis by enhanced levels of MIP-1alpha in BALB/c mice in vitro. Experimental Hematology 35 1100-1108 Lee JC, Yu MK, Lee R, Lee YH, Jeon JG, Jhee EC, Yoo ID and Yi HK (2008) Terrein reduces pulpal inflammation in human dental pulp cells. Journal of Endodology 34 433-437 Lee JH, Choi YH, Kang HS and Choi BT (2004) An aqueous extract of Platycodi radix inhibits LPS-induced NF-kB nuclear translocation in human cultured airway epithelial cells. International Journal of Molecular Medicine 13 843-847 Lee JH, Choi JK, Noh MS, Hwang BY, Hong YS and Lee JJ (2004) Anti-inflammatory effect of kamebakaurin in in vivo animal models. Planta Medica 70 526-530 Lee JH, Jung HS, Giang PM, Lee S, Jin X, Son PT, Lee D, Hong YS, Lee K and Lee JJ (2006) Blockade of NF-kB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analogue from Alpinia conchigera. Journal of Pharmacology and Experimental Therapeutics 316 271-278 Lee JH, Kim M, Im YS, Choi W, Byeon SH and Lee HK (2008) NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. Investigative Ophthalmology and Visual Sciences 49 1827-1835
Lee JH, Ko
WS, Kim YH, Kang HS, Kim HD and Choi BT (2001) Anti-inflammatory effect of the
aqueous extract from Lonicera japonica flower is related to inhibition of
NF-kB activation through reducing I-kBa degradation in rat liver.
International Journal of Molecular Medicine 7 79-83 Lee JH, Koo TH, Yoon H, Jung HS, Jin HZ, Lee K, HOng YS and Lee JJ (2006) Inhibition of NF-kB activation through targeting IkB kinase by celastrol, a quinone methide triterpenoid. Biochemical Pharmacology in press Lee JH, Hwang BY, Kim KS, Nam JB, Hong YS and Lee JJ (2003) Suppression of RelA/p65 transactivation activity by a lignoid manassantin isolated from Saururus chinensis. Biochemical Pharmacology 66 1925-1933 Lee JH, Lee J, Seo GH, Kim CH and Ahn YS (2007) Heparin inhibits NF-kB activation and increases cell death in cerebral endothelial cells after oxygen-glucose deprivation. Journal of Molecular Neuroscience 32 145-154 Lee JH, Oh GT, Park SY, Choi JH, Park JG, Kim CD, Lee WS, Rhim BY, Shin YW and Hong KW (2005) Cilostazol reduces atherosclerosis by inhibition of superoxide and TNF-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol. J Pharmacol Exp Ther in press Lee JH, Park EJ, Kim OS, Kim HY, Joe EH and Jou I (2005) Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells. Glia 50 66-79 Lee J-H, Koo
TH, Hwang BY and Lee JJ (2002) Kaurane diterpene, kamebakaurin, inhibits NF-kB
by directly targeting DNA-binding activity of p50 and blocks the expression of
antiapoptotic target genes. Journal of Biological Chemistry 277 18411-18420 Lee J-H, Li
Y, Doerre S, Sista P, Ballard DW, Greene WC and Franza Jr BR (1991) A member
of the set of NF-kB binding proteins, HIVEN86A, is a product of the human
c-rel proto-oncogene. Oncogene 6 665-667 Lee J-I and
Burckhart GJ (1999) Nuclear factor kB: important transcription factor and
therapeutic target. Journal of Clinical Pharmacology 38 981-993 Lee JI,
Ganster RW, Geller DA, Burckart GJ, Thomson AW and Lu L (1999) Cyclosporin A
inhibits the expression of costimulatory molecules on in vitro-generated
dendritic cells: association with reduced nuclear translocation of nuclear
factor kB. Transplantation 68 1255-1263 Lee JJ, Huang WT, Shao DZ, Liao JF and Lin MT (2004) Blocking NF-kappaB activation may be an effective strategy in the Fever therapy. Japanese Journal of Physiology 53 367-375 Lee JJ, Liao HF, Yang YC, Liu CL, Chen YY, Lin CP and Chen YJ (2006) Platonin modulates differentiation and maturation of human monocyte-derived dendritic cells. International Immunopharmacology 6 287-293 Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA (2004) Differences in signaling pathways by IL-1{beta} and IL-18. Proceedings of the National Academy of Sciences USA 101 8815-8820 Lee JL, Chang CJ, Chueh LL and Lin CT (2006) Secreted Frizzled related protein 2 (sFRP2) decreases susceptibility to UV-induced apoptosis in primary culture of canine mammary gland tumors by NF-kB activation or JNK suppression. Breast Cancer Research and Treatment 100 49-58 Lee J, Ivanova EV, Seong IS, Cashorali T, Kohane I, Guella JF and Macdonald ME (2007) Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism. PLoS Genetics 3 e135 Lee JR (2003) Reactive oxygen species play roles on B cell surface receptor CD40-mediated proximal and distal signaling events: effects of an antioxidant, N-acetyl-L-cysteine treatment. Mol Cell Biochem 252 1-7 Lee JR, Ha YJ and Kim HJ (2003) Cutting edge: induced expression of a RhoA-specific guanine nucleotide exchange factor, p190RhoGEF, following CD40 stimulation and WEHI 231 B cell activation. Journal of Immunology 170 19-23
Lee JR, Seok
CJ, Kim JS, Chang JM and Seo JW (2001) Expression of NF-kB and cytokines in
chronic rejection of transplanted murine heart. Journal of Korean Medical Science 16 397-406 Lee JS, Jung ID, Jeong YI, Lee CM, Shin YK, Lee SY, Suh DS, Yoon MS, Lee KS, Choi YH, CHung HY and Park YM (2007) d-pinitol inhibits Th1 polarization via the suppression of dendritic cells. International Immunopharmacology 7 791-804 Lee JS,
Kahlon SS, Culbreth R and Cooper AD, Jr. (1999) Modulation of monocyte
chemokine production and nuclear factor kappa B activity by oxidants. Journal
of Interferon and Cytokine Research 19 761-767 Lee JS, Kim HS, Hahm KB, Sohn MW, Yoo M, Johnson JA and Surh YJ (2007) Inhibitory effects of 7-carboxymethyloxy-3',4',5-trimethoxy flavone (DA-6034) on Helicobacter pylori-induced NF-kB activation and iNOS expression in AGS cells. Annals of New York Academy of Sciences 1095 527-535 Lee JS, Kim IH and Kim SY (2006) Changes in gene expression with increased transglutaminase 2 in a SH-SY5Y cell line. Frontiers in Bioscience 11 2774-2781 Lee JS, Kim SG, Kim HK, Lee TH, Jeong YI, Lee CM, Yoon MS, Na YJ, Suh DS, Park NC, Choi IH, Kim GY, Choi YH, Chung HY and Park YM (2006) Silibinin polarizes Th1/Th2 immune responses through the inhibition of immunostimulatory function of dendritic cells. Journal of Cellular Physiology 210 385-397 Lee JS, Lee JC, Lee CM, Jung ID, Jeong YI, Seong EY, Chung HY and Park YM (2007) Outer membrane protein A of Acinetobacter baumannii induces differentiation of CD4(+) T cells toward a Th1 polarizing phenotype through the activation of dendritic cells. Biochemical Pharmacology 74 86-97 Lee JS, Lee Jy, Son JW, Oh JH, Shin DM, Yuk JM, Song CH, Paik TH and Jo EK (2008) Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. Scandinavian Journal of Immunology 67 77-85 Lee
JS, Nauseef WM, Moeenrezakhanlou A, Sly LM, Noubir S, Leidal KG, Schlomann
JM, Krystal G and Treiner NE (2007) Monocyte p110a phosphatidylinositol
3-kinase regulates phagocytosis, the phagocyte oxidase, and cytokine
production. Lee JS, Oh TY,
Ahn BO, Cho H, Kim WB, Kim YB, Surh YJ, Kim HJ and Hahm KB (2001) Involvement
of oxidative stress in experimentally induced reflux esophagitis and Barrett's
esophagus: clue for the chemoprevention of esophageal carcinoma by
antioxidants. Mutation Research 480-481 189-200 Lee JS, Ryu CH, Moon NH, Kim SJ, Park SY and Suh KT (2008) Changes in serum levels of receptor activator of nuclear factor-kB ligand, osteoprotegerin, IL-6 and TNF-a in patients with a concomitant head injury and fracture. Arch Orthop Trauma Surg in press Lee JW, Lee MS, Kim TH, Lee HJ, Hong SS, NOh YH, Hwang BY, Ro JS and Hong JT (2007) Inhibitory effect of inflexinol on nitric oxide generation and iNOS expression via inhibition of NF-kB activation. Mediators of Inflammation 2007 93148 Lee
JY, Huerta-Yepez S, Vega M, Baritaki S, Spandidos DA and Bonadvida B (2007)
The NO TRAIL to YES TRAIL in cancer therapy. Lee JY, Je JH, Jung KJ, Yu BP and Chung HY (2004) Induction of endothelial iNOS by 4-hydroxyhexenal through NF-kB activation. Free Radical Biology and Medicine 37 539-548 Lee JY, Jhun BS, Oh YT, Lee JH, Choe W, Baik HH, Ha J, Yoon KS, Kim SS and Kang I (2005) Activation of adenosine A(3) receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells. Neuroscience Letters in press Lee JY, Kim JS, Kim JM, Kim N, Jung HC and Song IS (2007) Simvastatin inhibits NF-kB signaling in intestinal epithelial cells and ameliorates acute murine colitis. International Immunopharmacology 7 241-248 Lee JY, Kim JY, Lee YG, GRhee MH, Hong EK and Cho JY (2008) Molecular mechanism of macrophage activation by exopolysaccharides from liquid culture of Lentinus edodes. Journal of Microbiology & Biotechnology 18 355-364 Lee JY, Moon SK, Hwang CW, Nam KS, Kim YK, Yoon HD, Kim MG and Kim CH (2005) A novel function of benzyl isothiocyanate in vascular smooth muscle cells: The role of ERK1/2, cell cycle regulation, and matrix metalloproteinase-9. Journal of Cell Physiology 203 493-500 Lee JY, Plakidas A, Lee WH, Heikkinen A, Chanmugam P, Bray G and Hwang DH (2003) Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. Journal of Lipid Research 44 479-486 Lee JY, Rhee MH and Cho JY (2008)Novel modulatory effects of SDZ 62-434 on inflammatory events in activated macrophage-like and monocytic cells. Naunyn Schmiedebergs Arch Pharmacol in press Lee JY, Shin JW, Chun KS, Park KK, Chung WY, Bang YJ, Sung JH and Surh YJ (2004) Anti-tumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol type ginsenosides in mouse skin. Carcinogenesis 26 359-367 Lee JY, Woo ER and Kang KW (2005) Inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation. Journal of Ethnopharmacology 9 561-566 Lee JY, Ye J, Gao Z, Youn HS, Lee WH, Zhao L, Sizemore N and Hwang DH (2003) Reciprocal modulation of TLR4-signaling pathways involving MyD88 and PI3K/AKT by saturated and polyunsaturated fatty acids. Journal of Biological Chemistry 278 37041-37051 Lee JY, Yu BP and Chung HY (2005) Activation mechanisms of endothelial NF-kB, IKK, and MAP kinase by tert-butyl hydroperoxide. Free Radicical Research 39 399-409 Lee JY, Zhao L, Youn HS, Weatherill AR, Tapping R, Feng L, Lee WH, Fitzgerald K and Hwang DH (2004) Saturated fatty acid activates but polyunsaturated fatty acid inhibits toll-like receptor 2 dimerized with toll-like receptor 6 or 1. Journal of Biological Chemistry 279 16971-16979 Lee K, Burgoon LD, Lamb L, Dere E, Zacharewski TR, Hogenesch JB and Lapres JJ (2006) Identification and characterization of genes susceptible to transcriptional cross-talk between the hypoxia and dioxin signaling cascades. Chemical Research and Toxicology 19 1284-1293 Lee KA, Cho KJ, Kim SH, Shim JH, Lim JS, Cho DH, Song MS, Dinarello CA and Yoon DY (2005) IL-18 E42A mutant is resistant to the inhibitory effects of HPV-16 E6 and E7 oncogenes on the IL-18-mediated immune response. Cancer Letters 229 261-270 Lee KE, Kim JW, Jeong KY, Kim KE, Yong TS and Sohn MH (2007) Regulation of German cockroach extract-induced IL-8 expression in human airway epithelial cells. Clinical and Experimental Allergy 37 1364-1373 Lee KH, Feig C, Tchikov V, Schickel R, Hallas C, Schutze S, Peter ME and Chan AC (2006) The role of receptor internalization in CD95 signaling. EMBO Journal 25 1009-1023 Lee KH, Hwang YH, Lee CT, Kim YW, Han SK, Shim YS and Yoo CG (2004) The heat-shock-induced suppression of the IkB/NF-kB cascade is due to inactivation of upstream regulators of IkBa through insolubilization. Experimental Cell Research 299 49-56 Lee KH, Lee CT, Kim YW, Han SK, Shim YS and Yoo CG (2005) Heat shock protein 70 negatively regulates the heat-shock-induced suppression of the IkB/NF-kB cascade by facilitating IkB kinase renaturation and blocking its further denaturation. Experimental Cell Research 307 276-284 Lee KH, Yun SJ, Nam KN, Gho YS and Lee Eh (2007) Activation of microglial cells by ceruloplasmin. Brain Research in press Lee KJ, Hwang SJ, Choi JH and Jeong HG (2008) Saponins derived from the roots of Platycodon grandiflorum inhibit HT-1080 cell invasion and MMPs activities: Regulation of NF-kB activation via ROS signal pathway. Cancer Letters in press Lee KJ, Kim YM, Kim DY, Jeoung D, Han K, Lee ST, Lee YS, Park KH, Park JH, Kim DJ and Hahn JH (2006) Release of heat shock protein 70 (Hsp70) and the effects of extracellular Hsp70 on matric metalloproteinase-9 expression in human monocytic U937 cells. Experimental Molecular Medicine 38 364-374 Lee KK, Kwong WH, Chau FT, Yew DT and Chan WY (2002) Pien Tze Huang protects the liver against carbon tetrachloride-induced damage. Pharmacology and Toxicology 91 185-192 Lee KM, Kang NJ, Han JH, Lee KW and Lee HJ (2007) Myricetin down-regulates phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kB. Journal of Agriculture and Food Chemistry in press Lee KM, Kang BS, Lee HL, Son SJ, Hwang SH, Kim DS, Park JS and Cho HJ (2004) Spinal NF-kB activation induces COX-2 upregulation and contributes to inflammatory pain hypersensitivity. European Journal of Neuroscience 19 3375-3381 Lee
KM, Park KG, Kim YD, Lee HJ, Kim HT, Cho WH, Kim HS, Han SW, Koh GY, Park JY,
Lee KU, Kim JG and Lee IK (2006) Alpha-lipoic acid inhibits fractalkine
expression and prevents neointimal hyperplasia after balloon injury in rat
carotid artery. Lee KM, Yeo M, Choue JS, Jin JH, Park SJ, Cheong JY, Lee KJ, Kim JH and Hahm KB (2004) Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori-induced Ggastric epithelial cytotoxicity via the blockage of TLR-4 signaling. Heliobacter 9 632-642 Lee
KS, Kim SR, Park SJ, Min KH, Lee KY, Jin SM, Yoo WH and Lee YC (2006)
Antioxidant down-regulates IL-18 expression in asthma. Lee KS, Lee SJ, Park HJ, Chung JP, Han KH, Chon CY, Lee SI and Moon YM (2001) Oxidative stress effect on the activation of hepatic stellate cells. Yonsei Medical Journal 42 1-8 Lee KS, Park SJ, Kim SR, Min KH, Jin SM, Lee HK and Lee YC (2006) Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma. Journal of Immunology 177 5248-5257 Lee KS, Park JH, Lee S, Lim HJ, Choi HE and Park HY (2007) HB-EGF induces delayed STAT3 activation via NF-kB mediated IL-6 secretion in vascular smooth muscle cell. Biochimica et Biophysica Acta in press Lee KS, Kim SR, Park HS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Han HJ, Lee YR, Kim JS, Atlas D and Lee YC (2007) A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-kB and hypoxia-inducible factor-1a. Experimental and Molecular Medicine 39 756-768 Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Li L and Lee YC (2006) An antioxidant modulates expression of receptor activator of NF-kB in asthma. Experimental and Molecular Medicine 38 217-229 Lee KU, Lee IK, Han J, Song DK, Kim YM, Song HS, Kim HS, Lee WJ, Koh EH, Song KH, Han SM, Kim MS, Park IS and Park JY (2005) Effects of recombinant adenovirus-mediated uncoupling protein 2 overexpression on endothelial function and apoptosis. Circulation Research 96 1200-1207 Lee KW, Chun KS, Lee JS, Kang KS, Surh YJ and Lee HJ (2004) Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester. Annals of the New York Academy of Sciences 1030 501-507 Lee KW, Jung J, Lee Y, Kim TY, Choi SY, Park J, Kim DS and Kwon HJ (2006) Immunostimulatory oligodeoxynucleotide isolated from genome wide screening of Mycobacterium bovis chromosomal DNA. Molecular Immunology 43 2107-2118 Lee KW, Kang NJ, Heo YS, Rogozin EA, Pugliese A, Hwang MK, Bowden GT, Bode AM, Lee HJ and Dong Z (2008) Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. Cancer Research 68 946-955 Lee KW, Kim DS, Kwon HJCG sequence- and phosphorothioate backbone modification-dependent activation of the NF-kB-responsive gene expression by CpG-oligodeoxynucleotides in human RPMI 8226 B cells. Molecular Immunology 41 955-964 Lee KW, Kim JH, Lee HJ and Surh Aj (2005) Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kB transcriptional activity in MCF10A human breast epithelial cells. Antioxidants and Redox Signaling 7 1612-1620 Lee KW, Kim MS, Kang NJ, Kim DH, Surh YJ, Lee HJ and Moon A (2006) H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kB: An implication for invasive phenotype in rat liver epithelial cells. International Journal of Cancer 119 1767-1775 Lee KW, Kundu JK, Kim SO, Chun KS, Lee HJ and Surh YJ (2006) Cocoa polyphenols inhibit phorbol ester-induced superoxide anion formation in cultured HL-60 cells and expression of cyclooxygenase-2 and activation of NF-kB and MAPKs in mouse skin in vivo. Journal of Nutrition 136 1150-1155 Lee
KW, Lee Y, Kim DS and Kwon HJ (2006) Direct role of NF-kB activation in
Toll-like receptor-triggered HLA-DRA expression. Lee KW, Lee Y, Kwon HJ, Kim DS (2005) Sp1-associated activation of macrophage inflammatory protein-2 promoter by CpG-oligodeoxynucleotide and lipopolysaccharide. Cell Mol Life Sci 62 188-198 Lee KY, Chang W, Qiu D, Kao PN and Rosen GD (1999) PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells. Journal of Biological Chemistry 274 13451-13455 Lee KY, D'Acquisto F, Hayden MS, Shim JH and Ghosh S (2005) PDK1 nucleates T cell receptor-induced signaling complex for NF-kB activation. Science 308 114-118 Lee KY, Ho SC, Lin HC, Lin SM, Liu CY, Huang CD, Wang CH, CHung KF and Kuo HP (2006) Neutrophil-derived elastase induces TGF-beta1 secretion in human airway smooth muscle via NF-kB pathway. American Journal of Respiratory Cell and Molecular Biology 35 407-414 Lee KY, Ito K, Hayashi R, Jazrawi EP, Barnes PJ and Adcock IM (2006) NF-kB and activator protein 1 response elements and the role of histone modifications in IL-1b-induced TGF-b1 gene transcription. Journal of Immunology 176 603-615 Lee KY and Jeon YJ (2003) Polysaccharide isolated from Poria cocos sclerotium induces NF-kB/Rel activation and iNOS expression in murine macrophages. International Immunopharmacology 3 1353-1362 Lee KY, Jeon YJ (2005) Macrophage activation by polysaccharide isolated from Astragalus membranaceus. International Immunopharmacology 5 1225-1233 Lee KY, Lee MH, Chang IY, Yoon SP, Lim DY and Jeon YJ (2006) Macrophage activation by polysaccharide fraction isolated from Salicornia herbacea. Journal of Ethnopharmacology 103 372-378 Lee KY, You HJ, Jeong HG, Kang JS, Kim HM, Rhee SD and Jeon YJ (2004) Polysaccharide isolated from Poria cocos sclerotium induces NF-kB/Rel activation and iNOS expression through the activation of p38 kinase in murine macrophages. International Immunopharmacology 4 1029-1038 Lee LF, Lih CJ, Huang CJ, Cao T, Cohen SN and McDevitt HO (2008) Genomic expression profiling of TNF-a-treated BDC2.5 diabetogenic CD4+ T cells. Proceedings of the National Academic of Sciences USA in press Lee M and
Jeon YJ (2001) Paclitaxel-induced immune suppression is associated with NF-kB
activation via conventional PKC isotypes in lipopolysaccharide- stimulated 70Z/3 pre-B lymphocyte tumor cells. Molecular Pharmacology 59 248-253 Lee M, Kim JY and Koh WS (2004) Apoptotic effect of PP2 a Src tyrosine kinase inhibitor, in murine B cell leukemia. Journal of Cellular Biochemistry 93 629 Lee M and Koh WS (2003) Raf-independent and MEKK1-dependent activation of NF-kB by hydrogen peroxide in 70Z/3 pre-B lymphocyte tumor cells. Journal of Cellular Biochemistry 88 545-556
Lee M and
Yang KH (2000) 2-Acetylaminofluorene suppresses immune response through the
inhibition of nuclear factor-kB activation during the early stage of B cell
development. Toxicology Letters 114 173-180 Lee MH, Kim JY, Yoon JH, Lim HJ, Kim TH, Jin C, Kwak WJ, Han Ck and Ryu JH (2006) Inhibition of nitric oxide synthase expression in activated microglia and peroxynitrite scavenging activity by Opuntia ficus indica var. saboten. Phytotherapy Research 20 742-747 Lee MH, Lee JM, Jun SH, Ha CG, Lee SH, Kim NW, Lee JH, Ko NY, Mun SH, Park SH, Kim BK, Her E, KIm YM and Choi WS (2007) In-vitro and in-vivo anti-inflammatory action of the ethanol extract of Trachelospermi caulis. Journal of Pharmacy and Pharmacology 59 123-130 Lee MH, Lee JM, Jun SH, Lee SH, Kim NW, Lee JH, Ko NY, Mun SH, Kim BK, Lim BO, Choi DK and Choi WS (2007) The anti-inflammatory effects of Pyrolae herba extract through the inhibition of the expression of inducible nitric oxide synthase (iNOS) and NO production. Journal of Ethnopharmacology in press Lee MH, Song HK, Ko GJ, Kang YS, Han SY, Han KH, Kim HK, Han JY and Cha Dr (2008) Angiotensin receptor blockers improve insulin resistance in type 2 diabetic rats by modulating adipose tissue. Kindey International in press Lee
MJ, Hsu
JD, Lin CL, Lin MH, Yuan SC and Wang CJ (2002) Induction of epidermal
proliferation and expressions of PKC and NF-kB by betel quid extracts in
mouse: the role of lime-piper additives in betel quid. Chemico-Biological Interactions 140
35-48 Lee MJ, Kim MJ, Song YS, SOng YO and Moon GS (2008) Bamboo culm extract supplementation elevates HDL-cholesterol and ameliorates oxidative stress in C57BL/6 mice fed atherogenic diet. Journal of Medicine and Food 11 69-77 Lee MJ, Park WH, Song YS, Lee YW, Song YO and Moon GS (2008) Effect of bamboo culm extract on oxidative stress and genetic expression: Bamboo culm extract ameliorates cell adhesion molecule expression and NFkB activity through the suppression of the oxidative stress. Clinical Nutrition in press Lee MJ, Yang CW, Jin DC, Chang YS, Bang BK and Kim YS (2003) Bone morphogenetic protein-7 inhibits constitutive and interleukin-1beta-induced monocyte chemoattractant protein-1 expression in human mesangial cells: role for JNK/AP-1 pathway. Journal of Immunology 170 2557-2563 Lee MS, Chang I and Kim S (2004) Death effectors of beta-cell apoptosis in type 1 diabetes. Molecular Genetics and Metabolism 83 82-92 Lee MS and Kim YJ (2007) Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annual Review of Biochemistry in press Lee MY, Heo JS and Han HJ (2006) Dopamine regulates cell cycle regulatory proteins via cAMP, Ca(2+)/PKC, MAPKs, and NF-kB in mouse embryonic stem cells. Journal of Cellular Physiology 208 399-406 Lee MY, Jung SVC, Lee JH and Han HJ (2008) Estradiol-17beta protects against hypoxia-induced hepatocyte injury through ER-mediated upregulation of Bcl-2 as well as ER-independent antioxidant effects. Cell Research 18 491-499 Lee MY, Kim WJ, Kang YJ, Jung YM, Kang YM, Suk K, Park JE, Choi EM, Choi BKJ, Kwon BS and Lee WH (2006) Z39Ig is expressed on macrophages and may mediate inflammatory reactions in arthritis and atherosclerosis. Journal of Leukoctye Biology 80 922-928 Lee NK, Choi HK, Kim DK and Lee SY (2006) Rac1 GTPase regulates osteoclast differentiation through TRANCE-induced NF-kB activation. Molecular and Cellular Biochemistry 281 55-61 Lee NK, Choi YG, Baik JY, Han SY, Jeong DW, Bae YS, Kim N and Lee SY (2005) A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood 106 852-859 Lee NK and Lee SY (2002) Modulation of life and death by the tumor necrosis factor receptor-associated factors (TRAFs). Journal of Biochemistry and Molecular Biology 35 61-66 Lee NP, Leung KW, Wo JY, Tam PC, Yeung WS and Luk JM (2006) NF-kB signaling blockade by Bay 11-7085 during early cardiac morphogenesis induces alterations of the outflow tract in chicken heart. Apoptosis 11 1215-1229 Lee PY, Tsai PS, Huang YH and Huang CJ (2008) Inhibition of Toll-like receptor-4, nuclear factor-kB and mitogen activation protein kinase by lignocaine may involve voltage-sensitive sodium channels. Clincal and Experimental Pharmacology and Physiology in press Lee R and
Collins T (2001) Nuclear factor-kB and cell survival: IAPs call for support.
Circulation Research 88 262-264 Lee R,
Beauparlant P, Elford H, Ponka P and Hiscott J (1997) Selective inhibition of
IkBa phosphorylation and HIV-1 LTR-directed gene expression by novel
antioxidant compounds. Virology 234 277-290 Lee R-m,
Gillet G, Brunside J, Thomas SJ and Neiman P (1999) Role of Nr13 in regulation
of programmed cell death in the bursa of Fabricius. Genes & Development 13
718-728 Lee S, Andrieu C, Saltel F, Destaing O, Auclair J, Pouchkine V, Michelon J, Salaun B, Kobayashi R, Jurdic P, Kieff ED and Sylla BS (2004) IkB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation. Proceedings of the National Academy of Sciences USA 101 17416-17421 Lee S, Chung J, Ha IS, Yi K, Lee JE, Kang HG, Choi I, Oh KH, Kim JY, Surh Cd and Ahn C (2007) Hydrogen peroxide increases human leukocyte adhesion to porcine aortic endothelial cells via NFkB-dependent up-regulation of VCAM-1. International Immunology in press Lee S, Hong J, Choi SY, Oh SB, Park K, Kim JS, Karin M and Lee SJ (2004) CpG oligodeoxynucleotides induce expression of proinflammatory cytokines and chemokines in astrocytes: the role of c-Jun N-terminal kinase in CpG ODN-mediated NF-kB activation. Journal of Neuroimmunology 153 50-63 Lee S, Kim W, Kang KP, Moon SO, Sung MJ, Kim DH, Kim HJ and Park SK (2005) Agonist of peroxisome proliferator-activated receptor-{gamma}, rosiglitazone, reduces renal injury and dysfunction in a murine sepsis model. Nephrology, Dialysis, Transplantation 20 1057-1065 Lee S, Kim W, Moon SO, Sung MJ, Kim DH, Kang KP, Jang KY, Lee SY, Park BH, Koh GY and Park SK (2006) Renoprotective effect of COMP-angiopoietin-1 in db/db mice with type 2 diabetes. Nephrology, Dialysis & Transplantation in press Lee S, Lee M and Kim SH (2008) Eupatilin inhibits H(2)O(2)-induced apoptotic cell death through inhibition of mitogen-activated protein kinases and nuclear factor-kB. Food Chemistry and Toxicology in press Lee S, Moon SO, Kim W, Sung MJ, Kim DH, Kang KP, Jang YB, Lee JE, Jang KY, Lee SY and Park SK (2006) Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury. Nephrology, Dialysis, Transplantation 21 2085-2095 Lee S, Park HH, Son HY, Ha JH, Lee MG, Oh TY, Sohn DH, Jeong TC, Lee SH, Son JK, Lee SG, Jun CD and Kim SH (2006) DA-9601 inhibits activation of the human mast cell line HMC-1 through inhibition of NF-kB. Cell Biology and Toxicology in press Lee S and Rivier C (2005) Role played by hypothalamic NF-kB in alcohol-mediated activation of the rat hypothalamic-pituitary-adrenal axis. Endocrinology 146 2006-2014 Lee S, Kim W, Moon SO, Sung MJ, Kim DH, Kang KP, Jang YB, Lee JE, Jang KY and Park SK (2006) Rosiglitazone ameliorates cisplatin-induced renal injury in mice. Nephrology, Dialysis, Transplantation 21 2096-2105 Lee S, Oh HM, Lim WB, CHou EJ, Park YN, Kim JA, Choi JY, HOng SJ, Oh HK, Son JK, Lee SH, Kim OJ, Choi HR and Jun CD (2008) Gene induction by glycyrol to apoptosis through endonuclease G in tumor cells and prediction of oncogene function by microarray analysis. Anticancer Drugs 19 503-515 Lee S, Suk K, Kim IK, Jang IS, Park JW, Johnson VJ, Kwon TK, Choi BJ and Kim SH (2008) Signaling pathways of bisphenol A-induced apoptosis in hippocampal neuronal cells: Role of calcium-induced reactive oxygen species, mitogen-activated protein kinases, and nuclear factor-kB. Journal of Neuroscience Research in press Lee SA, Fitzgerald SM, Huang SK, Li C, Chi DS and Krishnaswamy G (2004) Molecular regulation of IL-13 and MCP-1 expression in human mast cells by IL-1beta. American Journal of Respiratory Cell and Molecular Biology 31 283-291 Lee SA, Park SH and Kim BC (2008) Raloxifene, a selective estrogen receptor modulator, inhibits lipopolysaccharide-induced nitric oxide production by inhibiting the phosphatidylinositol 3-kinase/Akt/nuclear factor-kB pathway in RAW264.7 macrophage cells. Molecules and Cells in press Lee SB, Hong SH, Kim H and Um HD (2005) Co-induction of cell death and survival pathways by phosphoinositide 3-kinase. Life Sciences 78 91-98 Lee SB, Park J, Jung JU and Chung J (2005) Nef induces apoptosis by activating JNK signaling pathway and inhibits NF-kB-dependent immune responses in Drosophila. Journal of Cell Science 118 1851-1859 Lee SB and Schorey JS (2005) Activation and mitogen-activated protein kinase regulation of transcription factors Ets and NF-kB in Mycobacterium-infected macrophages and role of these factors in tumor necrosis factor alpha and nitric oxide Synthase 2 promoter function. Infection and Immunity 73 6499-6507 Lee
SE, Kim SY, Jeong BC, Kim YR, Bae SJ, Ahn OS, Lee JJ, Song HC, Kim JM, Choy
HE, Chung SS, Kweon MN and Rhee JH (2006) A bacterial flagellin, Vibrio
vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective
immunity. Lee SG, Choi JK, Choi BH, Lim Y, Kim YH, Lee KH, Shin JC and Ahn WS (2006) The effect of adenosine 5'-triphosphate on calcium mobilization and cell proliferation in cervical cancer cells. European Journal of Obstettics, Gynecology, and Reproductive Biology 127 110-114 Lee SH, Chung YH, Cho NH, Gwack Y, Feng P and Jung JU (2004) Modulation of T-cell receptor signal transduction by herpesvirus signaling adaptor protein. Molecular and Cellular Biology 24 5369-5382 Lee SH and
Hannink M (2002) Identification of nuclear import and export functions of IkBe.
Journal of Biological Chemistry 277 23358-23366 Lee SH and
Hannink M (2002) The N-terminal nuclear export sequence of IkBa is required
for RanGTP-dependent binding to CRM1. Journal of Biological Chemistry 276
23599-23606 Lee SH, Heo JS, Lee MY and Han HJ (2008) Effect of dihydrotestosterone on hydrogen peroxide-induced apoptosis of mouse embryonic stem cells. Journal of Cell Physiology in press Lee SH, Kim KK and Choi BK (2005) Upregulation of intercellular adhesion molecule 1 and proinflammatory cytokines by the major surface proteins of Treponema maltophilum and Treponema lecithinolyticum, the phylogenetic group IV oral spirochetes associated with periodontitis and eEndodontic infections. Infection and Immunity 73 168-176 Lee SH, Kim T, Park ES, Yang S, Jeong D, Choi Y and Rho J (2008) NHE10, a novel osteoclast-specific member of the Na(+)/H(+) exchanger family, regulates osteoclast differentiation and survival. Biochemical and Biophysical Research Communications in press Lee SH, Lee CW, Lee JW, Choi MS, Son DJ, Chung YB, Lee CK, Oh KW, Moon DC, Kwon BM and Hong JT (2005) Induction of apoptotic cell death by 2'-hydroxycinnamaldehyde is involved with ERK-dependent inactivation of NF-kB in TNF-a-treated SW620 colon cancer cells. Biochemical Pharmacology 70 1147-1157 Lee SH, Lee SY, Son DJ, Lee H, Yoo HS, Song S, Oh KW, Han DC, Kwon BM and Hong JT (2005) Inhibitory effect of 2'-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-kB activation in RAW 264.7 cells. Biochemical Pharmacology 69 791-799 Lee SH and Lim KT (2007) UDN glycoprotein regulates activities of manganese-superoxide dismutase, activator protein-1, and nuclear factor-kB stimulated by reactive oxygen radicals in lipopolysaccharide-stimulated HCT-116 cells. Cancer Letters in press Lee SH, Nishino M, Mazumdar T, Garcia GE, Galifione M, Lee FL, Lee CL, Liang A, Kim J, Feng L, Eissa NT, Lin SH and Yu-Lee LY (2005) 16-kDa prolactin down-regulates inducible nitric oxide synthase expression through inhibition of the signal transducer and activator of transcription 1/IFN regulatory factor-1 pathway. Cancer Research 65 7984-7992 Lee
SH, Park HH, Kim JE, Kim JA, Kim YH, Jun CD and Kim SH (2007) Allose gallates
suppress expression of pro-inflammatory cytokines through attenuation of NF-kB
in human mast cells. Lee SH, Park SG, Lim SO and Jung G (2005) The hepatitis B virus X protein up-regulates lymphotoxin alpha expression in hepatocytes. Biochimica et Biophysica Acta 1741 75-84 Lee
SH, Ryu JK, Lee KY, Woo SM, Park JK, Yoo JW, Kim YT and Yoon YB (2007)
Enhanced anti-tumor effect of combination therapy with gemcitabine and
apigenin in pancreatic cancer. Lee SH, Seo GS, Ko G, Kim JB and Sohn DH (2005) Anti-inflammatory activity of 20(S)-protopanaxadiol: enhanced heme oxygenase 1 expression in RAW 264.7 cells. Planta Medica 71 1167-1170 Lee SH, Seo GS and Sohn DH (2004) Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by butein in RAW 264.7 cells. Biochemical and Biophysical Research Communications 323 125-132 Lee SH, Seo MJ, Choi SM, Sohn YS, Kang KK, Ahn BO, Kwon JW and Yoo M (2005) DA-9201 shows anti-asthmatic effects by suppressing NF-kB expression in an ovalbumin-induced mouse model of asthma. Archives of Pharmacal Research 28 1350-1357 Lee SH, Sohn DH, Jin XY, Kim SW, CHoi SC and Seo GS (2007) 2',4',6'-Tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways. Biochemical Pharmacology in press Lee SH, Son SM, Son DJ, Kim SM, Kim TJ, Song S, Moon DC, Lee HW, Ryu JC, Yoon DY and Hong JT (2007) Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kB/IkB kinase signal pathway. Molecular Cancer Therapeutics 6 2786-2797 Lee SH, Song R, Lee MN, Kim CS, Lee H, Kong YY, Kim H and Jang SK (2008) A molecular chaperone glucose-regulated protein 94 blocks apoptosis induced by virus infection. Hepatology in press Lee
SH,
Stehlik C and Reed JC (2001) Cop, a caspase recruitment domain-containing
protein and inhibitor of caspase-1 activation processing. Journal of
Biological Chemistry 276 34495-34500 Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK and Kim YM (2003) Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing IkB kinase-dependent NF-kB activation. Molecules and Cells 16 97-105 Lee S-J,
Dimtchev A, Lavin MF, Dritschilo A and Jung M (1998) A novel ionizing
radiation-induced signaling pathway that activates the transcription factor
NF-kB. Oncogene 17 1821-1826 Lee SJ, Heo KS, Oh PS, Lim K and Lim KT (2004) Glycoprotein isolated from Ulmus davidiana Nakai inhibits TPA-induced apoptosis through nuclear factor-kB in NIH/3T3 cells. Toxicology Letters 146 159-174 Lee
SJ, Hou J
and Benveniste EN (1998) Transcriptional regulation of intercellular adhesion
molecule-1 in astrocytes involves NF-kB and C/EBP isoforms. Journal of
Neuroimmunology 92 196-207 Lee SJ, Kim HM, Cho YH, Park K, Kim EJ, Jung KH, Kim CH, Kim WJ and Moon SK (2007) Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase. Oncology Reports 18 729-736 Lee SJ and Lee S (2002) Toll-like receptors and inflammation in the CNS. Current Drug Targets in Inflammation and Allergy 1 181-191 Lee SJ and Lim KT (2006) 150kDa glycoprotein isolated from Solanum nigrum Linne stimulates caspase-3 activation and reduces inducible nitric oxide production in HCT-116 cells. Toxicology In Vitro 20 1088-1097 Lee SJ and Lim KT (2007) Glycoprotein isolated from Ulmus davidiana Nakai regulates expression of iNOS and COX-2 in vivo and in vitro. Food and Chemical Toxicology 45 990-1000 Lee SJ and Lim KT (2008) Inhibitory effect of 30-kDa phytoglycoprotein on expression of TNF-a and COX-2 via activation of PKCa and ERK 1/2 in LPS-stimulated RAW 264.7 cells. Molecular and Cellular Biochemistry in press Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG and Kim YM (2008) CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kB activation. Biochemical Pharmacology in press Lee SJ, Bae SS, Kim KH, Lee WS, Rhim BY, Hong KW and Kim CD (2007) High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kB pathway. FEBS Letters 581 4189-4194 Lee SJ, Bae S, Seomun Y, Son MJ and Joo CK (2008) The role of nuclear factor kB in lens epithelial cell proliferation using a capsular bag model. Opthalmic Research in press Lee SJ and Lim KT (2008) Cell death signal by glycine- and proline-rich plant glycoprotein is transferred from cytochrome c and nuclear factor kB to caspase 3 in Hep3B cells. Journal of Nutritional Biochemistry 19 166-174 Lee SJ and Lim KT (2007) Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice. Toxicology and Applied Pharmacology 225 198-205 Lee SJ and Lim KT (2008) Chemopreventive effect of plant originated glycoprotein on colitis-mediated colorectal cancer in A/J mice. Journal of Biomedical Sciences 154 111-121 Lee SJ, Oh PS, Ko JH, Lim K and Lim KT (2004) A 150-kDa glycoprotein isolated from Solanum nigrum L. has cytotoxic and apoptotic effects by inhibiting the effects of protein kinase C alpha, nuclear factor-kB and inducible nitric oxide in HCT-116 cells. Cancer Chemotherapy and Pharmacology 54 562-572 Lee SJ, Oh PS, Ko JH, Lim K and Lim KT (2006) Protective effect of glycoprotein isolated from Ulmus davidiana Nakai on carbon tetrachloride-induced mouse liver injury. Journal of Pharmacy and Pharmacology 58 143-152 Lee
SJ, Park
JY, Hou J and Benveniste EN (1999) Transcriptional regulation of the
intercellular adhesion molecule-1 gene by proinflammatory cytokines in human
astrocytes. Glia 25 21-32 Lee SJ, Park SS, Cho YH, Park K, Kim EJ, Jung KH, Kim SK, Kim WJ and Moon SK (2008) Activation of matrix metalloproteinase-9 by TNF-a in human urinary bladder cancer HT1376 cells: The role of MAP kinase signaling pathways. Oncology Reports 19 1007-1013 Lee SJ, Qin H and Benveniste EN (2007) Simvastatin inhibits IFN-gamma-induced CD40 gene expression by suppressing STAT-1alpha. Journal of Leukocyte Biology in press Lee SJ, Zhou
T, Choi C, Wang Z and Benveniste EN (2000) Differential regulation and
function of Fas expression on glial cells. Journal of Immunology 164 1277-1285 Lee SK and
Lorenzo JA (1999) Parathyroid hormone stimulates TRANCE and inhibits
osteoprotegerin messenger ribonucleic acid expression in murine bone marrow
cultures: correlation with osteoclast-like cell formation. Endocrinology 140
3552-3561 Lee SK,
Kalinowski J, Jastrzebski S and Lorenzo
JA (2002) 1,25 (OH)(2) vitamin D(3)-stimulated osteoclast formation in
spleen-osteoblast cocultures is mediated in part by enhanced IL-1a and
receptor activator of NF-kB ligand production in osteoblasts. Journal of
Immunology 169 2374-2380 Lee SK, Kim
CS, Yang WS, Kim SB, Park SK and Park JS (2002) Exogenous nitric oxide
inhibits tumor necrosis factor-alpha- or interleukin-1-beta-induced monocyte
chemoattractant protein-1 expression in human mesangial cells: role of
IkB-alpha and cyclic GMP. Nephron 92 780-787 Lee SK, Kim YW, Chi SG, Joo YS and Kim HJ (2008) The effect of Saccharomyces boulardii on human colon cells and inflammation in rats with trinitrobenzene sulfonic acid-induced colitis. Dig Dis Sci in press Lee SK, Kim
JH, Lee YC, Cheong J and Lee JW (2000) Silencing mediator of retinoic acid and
thyroid hormone receptors, as a novel transcriptional corepressor molecule of
activating protein-1, nuclear factor-kB, and serum response factor. Journal of
Biological Chemistry 275 12470-12474 Lee SK, Kim
JH, Yang WS, Kim SB, Park SK and Park JS (2002) Exogenous nitric oxide
inhibits VCAM-1 expression in human peritoneal mesothelial cells. role of
cyclic GMP and NF-kB. Nephron 90 447-454 Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK and Kim EC (2007) Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells. Clinical and Experimental Immunology inp ress Lee SK, Seo SH, Kim BS, Kim CD, Lee JH, Kang JS, Maeng PJ and Lim JS (2005) IFN-g regulates the expression of B7-H1 in dermal fibroblast cells. Journal of Dermatological Science in press Lee SM, Hong Nga NT, Park MH, Kim KS, Cho KJ, Moon DC, Kim HY, Yoon do Y and Hong JT (2004) EPO receptor-mediated ERK kinase and NF-kB activation in erythropoietin-promoted differentiation of astrocytes. Biochemical and Biophysical Research Communications 320 1087-1095 Lee SM and Kleiboeker SB (2005) Porcine arterivirus activates the NF-kB pathway through IkB degradation. Virology 342 47-59 Lee SO, Chang YC, Whang K, Kim CH and Lee IS (2007) Role of NAD(P)H:quinone oxidoreductase 1 on tumor necrosis factor-a-induced migration of human vascular smooth muscle cells. Cardiovascular Research 76 331-339 Lee SO, Jeong YJ, Kim M, Kim Ch and Lee IS (2007) Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-kB-dependent MMP-9 expression. Biochemical and Biophysical Research Communications in press Lee SO, Jeong YJ, Yu MH, Lee JW, Hwangbo MH, Kim CH and Lee IS (2006) Wogonin suppresses TNF-a-induced MMP-9 expression by blocking the NF-kB activation via MAPK signaling pathways in human aortic smooth muscle cells. Biochemical and Biophysical Research Communications 351 118-125 Lee SO, Lou W, Nadiminty N, Lin X and Gao AC (2005) Requirement for NF-kB in interleukin-4-induced androgen receptor activation in prostate cancer cells. Prostate 64 160-167 Lee SO, Pinder E, Chun JY, Lou W, Sun M and Gao AC (2008) Interleukin-4 stimulates androgen-independent growth in LNCaP human prostate cancer cells. Prostate 68 85-91 Lee SP, Youn SW, Cho HJ, Li L, Kim TY, Yook HS, Chung JW, Hur J, Yoon CH, Park KW, Oh BH, Park YB and Kim HS (2006) Integrin-linked kinase, a hypoxia-responsive molecule, controls postnatal vasculogenesis by recruitment of endothelial progenitor cells to ischemic tissue. Circulation 114 150-159 Lee ST, Chu K, Jung KH, Kim SJ, Kim DH, Kang KM, Hong NH, Kim JH, Ban JJ, Park HK, Kim SU, Park CG, Lee SK, Kim M and Roh JK (2007) Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke. Brain in press Lee SU, Sin HK, Min YK and Kim SH (2008) Emodin accelerates osteoblast differentiation through phosphatidylinositol 3-kinase activation and bone morphogenetic protein-2 gene expression. International Immunopharmacology 8 741-747 Lee SW, Han
SI, Kim HH and Lee ZH (2002) TAK1-dependent activation of AP-1 and c-Jun
N-terminal kinase by receptor activator of NF-kB. Journal of Biochemistry and Molecular Biology 35
371-376 Lee SW, Kwak HB, Chung WJ, Cheong H, Kim HH and Lee ZH (2003) Participation of protein kinase c beta in osteoclast differentiation and function. Bone 32 217-227 Lee SY, Cherla RP and Tesh VL (2006) Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1. Infection and Immunity in press Lee SY, Ha TY, Son DJ, Kim SR and Hong JT (2005) Effect of sesaminol glucosides on beta-amyloid-induced PC12 cell death through antioxidant mechanisms. Neuroscience Research 52 330-341 Lee SY,
Kaufman DR, Mora AL, Santana A, Boothby M and Choi Y (1998) Stimulus-dependent
synergism of the antiapoptotic tumor necrosis factor receptor-associated
factor 2 (TRAF2) and nuclear factor kB pathways. Journal of Experimental
Medicine 188 1381-1384 Lee SY, Lee HY, Kim SD, Jo SH, Shim JW, Lee HJ, Yun J and Bae YS (2008) Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells. Biocehmical and Biophysical Research Communications in press Lee SY, Lee JW, Lee H, Yoo HS, Yun YP, Oh KW, Ha TY and Hong JT (2005) Inhibitory effect of green tea extract on beta-amyloid-induced PC12 cell death by inhibition of the activation of NF-kB and ERK/p38 MAP kinase pathway through antioxidant mechanisms. Brain Research Molecular Brain Research 140 45-54 Lee SY, Lee
SY, Kandala G, Liou M-L, Liou H-C and Choi Y (1996) CD30/TNF
receptor-associated factor interaction: NF-kB activation and binding
specificity. Proceedings of the National Academy of Sciences USA 93 9699-9703 Lee SY, Son DJ, Lee YK, Lee JW, Lee HJ, Yun YW, Ha TY and Hong JT (2006) Inhibitory effect of sesaminol glucosides on lipopolysaccharide-induced NF-kB activation and target gene expression in cultured rat astrocytes. Neuroscience Research 56 204-212 Lee SY, Yuk DY, SOng HS, Yoon DY, Jung JK, Moon DC, Lee BS and Hong JT (2008) Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kB. European Journal of Pharmacology in press Lee TH, Shank J, Cusson N and Kelliher MA (2004) The kinase activity of Rip 1 is not required for TNF-alpha-induced IKK or p38 MAP kinase activation or for the ubiquitination of Rip 1 by Traf 2. Journal of Biological Chemistry 279 33185-33191 Lee TL, Alba D, Baxendale V, Rennert OM and Chan WY (2006) Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes. Genomics 88 18-33 Lee TL, Yeh J, Friedman J, Yan B, Yang X, Yeh NT, Van Waes C and Chen Z (2008) A signal network involving coactivated NF-kB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas. International Journal of Cancer in press Lee TH, Tai DI, Cheng CJ, Sun CS, Lin CY, Sheu MJ, Lee WP, Peng CY, Wang AH and Tsai SL (2006) Enhanced nuclear factor-kB-associated Wnt-1 expression in hepatitis B- and C-related hepatocarcinogenesis: identification by functional proteomics. Journal of Biomedical Science 13 27-39 Lee TK, Poon RT, Wo JY, Ma S, Guan XY, Myers JN, Altevogt P and Yuen AP (2007) Lupeol suppresses cisplatin-induced nuclear factor-kB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model. Cancer Research 67 8800-8809 Lee TL, Yang XP, Yan B, Friedman J, Duggal P, Bagain L, Dong G, Yeh NT, Wang J, Zhou J, Elkahloun A, Van Waes C and Chen Z (2007) A novel nuclear factor-kB gene signature is differentially expressed in head and neck squamous cell carcinomas in association with TP53 status. Clinical Cancer Research 13 5680-5691 Lee TS, Chang CC, Zhu Y and Shyy JY (2004) Simvastatin induces heme oxygenase-1. A novel mechanism of vessel protection. Circulation 110 1296-1302 Lee
TS, Park KK, Cho HS, Choo YA and Hwang M (2007) Effects of bioactive ceramics
on the pathogenesis of rat vascular smooth muscle cells treated with phorbol
12-myristate 13-acetate. Lee UJ, Chooung SR, Prakash KV, Lee EJ, Lee MY, Kim YJ, Han CW and Choi YC (2007) Dual knockdown of p65 and p50 subunits of NF-kB by siRNA inhibits the induction of inflammatory cytokines and significantly enhance apoptosis in human primary synoviocytes treated with tumor necrosis factor-alpha. Molecular Biology Reports in press Lee WI, Torgerson TR, Schumacher MJ, Yel L, Zhu Q and Ochs HD (2004) Molecular analysis of a large cohort of patients with the hyper IgM syndrome (HIGM). Blood 105 1881-1890 Lee WI, Zhu Q, Gambine E, Jin Y, Welcher AA and Ochs HD (2003) Inducible CO-stimulator molecule, a candidate gene for defective isotype switching, is normal in patients with hyper-IgM syndrome of unknown molecular diagnosis. Journal of Allergy and Clinical Immunology 112 958-964 Lee WJ (2008) Bacterial-modulated signaling pathways in gut homeostasis. Science Signaling 1 pe24 Lee WP, Tai DI, Tsai SL, Yeh CT, Chao Y, Lee SD and Hung MC (2003) Adenovirus type 5 E1A sensitizes hepatocellular carcinoma cells to gemcitabine. Cancer Research 63 6229-6236 Lee Y, Allport V, Sykes A, Lindstrom T, Slater D and Bennett P (2003) The effects of labour and of interleukin 1 beta upon the expression of nuclear factor kB related proteins in human amnion. Molecular Human Reproduction 9 213-218 Lee Y, Broxmeyer HE, Mantel C, Kwon HJ, Kim JW, Kim JS, Kwon D and Choe IS (2003) Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells. Experimental Molecular Medicine 35 222-226 Lee Y, Hyung SW, Jung HJ, Kim HJ, Staerk J, Constantinescu SN, chang EJ, Lee ZH, Lee SW and Kim HH (2007) The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon-{beta}-induced inhibitory signaling. Blood in press Lee Y, Sohn WJ, Kim DS and Kwon HJ (2004) NF-kB- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7. European Journal of Biochemistry 271 1094-1105
Lee YA, Kim YJ, Cho EJ and Yokozawa T (2007) Ameliorative
effects of proanthocyanidin on oxidative stress and inflammation in
Streptozotocin-induced diabetic rats. Lee YC, Lee KS, Park SJ, Park HS, Lim JS, Park KH, Im MJ, Choi IW, Lee HK and Kim UH (2004) Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid. FASEB Journal 18 1917-1919 Lee YJ, Choi HJ, Kang TW, Kim HO, Chung MJ and Park YM (2008) CBT-SL5, a bacteriocin from Enterococcus faecalis, suppresses the expression of interleukin-8 induced by propionibacterium acnes in cultured human of interleukin-8 induced by Propionibacterium acnes in cultured human keratinocytes. Journal of Microbiology and Biotechnology 18 1308-1316 Lee YJ and Han HJ (2005) Effect of adenosine triphosphate in renal ischemic injury: Involvement of NF-kB. Journal of Cell Physiology 204 792-799 Lee YJ and Han HJ (2007) Albumin-stimulated DNA synthesis is mediated by Ca2+/PKC as well as EGF receptor-dependent p44/42 MAPKs and NF-kB signal pathways in renal proximal tubule cells. American Journal of Physiology: Renal Physiology in press Lee YJ, Heo JS, Suh HN, Lee MY and Han HJ (2007) Interleukin-6 stimulates 14C-alpha-methyl-D-glucopyranoside uptake in renal proximal tubule cells: Involvement of STAT3, PI3K/Akt, MAPKs, and NF-kB. American Journal of Physiology: Renal Physiology in press Lee YJ, Kang DG, Kim JS adn Lee HS (2007) Lycopus lucidus inhibits high glucose-induced vascular inflammation in human umbilical vein endothelial cells. Vascular Pharmacology in press Lee YJ, Kang IJ, Bunger R and Kang YH (2004) Enhanced survival effect of pyruvate correlates MAPK and NF-kB activation in hydrogen peroxide-treated human endothelial cells. Journal of Applied Physiology 96 793-801 Lee YJ, Kang DG, Kim JS and Lee HS (2008) Effect of Buddleja officinalis on high glucose-induced vascular inflammation in human umbilical vein endothelial cells. Experimental Biology and Medicine in press
Lee Y-M, Miau L-H, Chang C-J and Lee S-C (1996) Transcriptional induction of the alpha-1
acid glycoportein (AGP) gene by synergistic interaction of two alternative activator forms of AGP/enhancer-binding protein (C/EBPb) and NF-kB or Nopp140.
Molecular and Cellular Biology 16 4257-4263 Lee Ym Seong MJ, Lee JW, Lee YK, Kim TM, Nam SY, Kim DJ, Yun YW, Kim TS, Han SY and Hong JT (2007) Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen. Journal of Veterinary Science 8 27-38 Lee YR, Lee JH, Noh EM, Kim EK, Song MY, Jung WS, Park SJ, Kim JS, Park JW, Kwon KB and Park BH (2008) Guggulsterone blocks IL-1b-mediated inflammatory responses by suppressing NF-kB activation in fibroblast-like synoviocytes. Life Sciences in press Lee YR, Shim HJ, Yu HN, Song EK, Park J, Kwon KB, Park JW, Rho HW, Park BH, Han MK and Kim JS (2005) Dimethylsulfoxide induces upregulation of tumor suppressor protein PTEN through nuclear factor-kB activation in HL-60 cells. Leukemia Research 29 401-405 Lee YR, Su CY, Chow NH, Lai WW, Lei HY, Chang CL, Chang TY, Chen SH, Lin YS, Yeh Tm and Liu HS (2007) Dengue viruses can infect human primary lung epithelia as well as lung carcinoma cells, and can also induce the secretion of IL-6 and RANTES. Virus Research in press Lee YR, Yu HN, Noh EM, Youn HJ, SOng EK, Han MK, Park CS, Kim BS, Park YS, Park BK, Lee SH and Kim JS (2007) TNF-a upregulates PTEN via NF-kB signaling pathways in human leukemic cells. Experimental & Molecular Medicine 39 121-127 Lee YS, Kang YS, Lee JS, Nicolova S and Kim JA (2004) Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells. Free Radical Research 38 405-412 Lee YS, Song YS, Giffard RG and Chan PH (2006) Biphasic role of nuclear factor-kB on cell survival and COX-2 expression in SOD1 Tg astrocytes after oxygen glucose deprivation. Journal of Cerebral Blood Flow and Metabolism in press Lee YS, Terzidou V, Lindstrom T, Johnson M and Bennett PR (2006) The role of CCAAT/enhancer-binding protein beta in the transcriptional regulation of COX-2 in human amnion. Molecular Human Reproduction in press Lee YW, Eum SY, Nath A and Toborek M (2004) Estrogen-mediated protection against HIV Tat protein-induced inflammatory pathways in human vascular endothelial cells. Cardiovascular Research 63 139-148 Lee YW, Han
SH, Suh JH, Jeon YJ and Yang KH (1998) Down-regulation of protein kinase C: a
potential mechanism for 2-amino-3-methylimidazo[4,5-f]quinoline-mediated
immunosuppression. Toxicology Letters 102-103 79-83 Lee YW,
Hennig B, Fiala M, Kim KS and Toborek M (2001) Cocaine activates redox-regulated
transcription factors and induces TNF-alpha expression in human brain
endothelial cells. Brain Research 920 125-133 Lee YW,
Hennig B, Yao J and Toborek M (2001) Methamphetamine induces AP-1 and NF-kB
binding and transactivation in human brain endothelial cells. Journal of Neuroscience Research 66 583-591 Lee YW, Hirani AA, Kyprianou N and Toborek M (2005) Human immunodeficiency virus-1 Tat protein up-regulates interleukin-6 and interleukin-8 expression in human breast cancer cells. Inflammation Research 54 380-389 Lee YW, Malecki A and Toborek M (2003) Estrogen-mediated protection against methamphetamine-induced inflammatory pathways in human brain endothelial cells. Journal of Neurochemistry 85 2 36 Lee YW, Park HJ, Son KW, Hennig B, Robertson LW and Toborek M (2003) 2,2',4,6,6'-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicology and Applied Pharmacology 189 1-10
Lee YW, Son
KW, Flora G, Hennig B, Nath A and Toborek M (2002) Methamphetamine activates
DNA binding of specific redox-responsive transcription factors in mouse brain.
Journal of Neuroscience Research 70 82-89 Lee YY, Kao CL, Tsai PH, Tsai TH, Chiou SH, Wu WF, Ku HH and WOng TT (2008) Caffeic acid phenethyl ester preferentially enhanced radiosensitizing and increased oxidative stress in medulloblastoma cell line. Childs Nervous System in press Lee YY, Yang SF, Ho WH, Lee YH and Hung SL (2007) Eugenol modulates cyclooxygenase-2 expression through the activation of nuclear factor kB in human osteoblasts. Journal of Endodontics 33 1177-1182 Lee ZH and Kim HH (2003) Signal transduction by receptor activator of nuclear factor kB in osteoclasts. Biochemical and Biophysical Research Communications 305 211-214 Leeman JR and Gilmore TD (2008) Alternative splicing in the NF-kB signaling pathway. Gene 423 97-107 Leeman JR, Weniger MA, Barth TD and Gilmore TD (2008) Deletion analysis and alternative splicing define a transactivation inhibitory domain in human oncoprotein REL. Oncogene 27 677-6781 Leeper-Woodford
SK and Detmer K (1999) Acute hypoxia increases alveolar macrophage tumor
necrosis factor activity and alters NF-kB expression. American Journal of
Physiology 276 L909-L916 Lefort S, Soucy-Faulkner A, Grandvaux N and Flamand L (2007) Binding of Kaposi's sarcoma-associated herpesvirus K-bZIP to interferon responsive factor 3 elements modulates antiviral genes expression. Journal of Virology 81 10950-10960 Lefranc F, Brotchi J and Kiss R (2005) Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. Journal of Clinical Oncology 23 2411-2422 Lefranc F, Mijatovic T, Mathieu V, Rorive S, Decaestecker C, Debeir O, Brotchi J, Van Ham P, Salmon I and Kiss R (2004) Characterization of gastrin-induced proangiogenic effects in vivo in orthotopic U373 experimental human glioblastomas and in vitro in human umbilical vein endothelial cells. Clinical Cancer Research 10 8250-8265 Lefstin JA
and Yamamoto KR (1998) Allosteric effects of DNA on transcriptional
regulators. Nature 392 885-888 Legarda D, Klein-Patel ME, Yim S, Yuk MH and Diamond G (2005) Suppression of NF-kB-mediated beta-defensin gene expression in the mammalian airway by the Bordetella type III secretion system. Cell Microbiol 7 489-497 Legarda-Addison D and Ting AT (2007) Negative regulation of TCR signaling by NF-kB2/p100. Journal of Immunology 178 7767-7778 Legembre P, Barnhart BC, and Peter ME (2004) The relevance of NF-kB for CD95 signaling in tumor cells. Cell Cycle 3 1235-1239 Legembre P, Barnhart BC, Zheng L, Vijayan S, Straus SE, Puck J, Dale JK, Lenardo M and Peter ME (2004) Induction of apoptosis and activation of NF-kB by CD95 require different signalling thresholds. EMBO Journal 5 1084-1089 Legembre P, Schickel R, Barnhart BC and Peter ME (2004) Identification of SNARK as a NF-kB regulated antiapoptotic kinase involved in CD95-induced motility and invasiveness. Journal of Biological Chemistry 279 46742-46747 Legendre F, Bogdanowicz P, Martin G, Domagala F, Leclercq S, Pujol JP and Ficheux H (2007) Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways. Clinical and Experimental Rheumatology 25 546-555 Leger DY, Liagre B and Beneytout JL (2006) Role of MAPKs and NF-kB in diosgenin-induced megakaryocytic differentiation and subsequent apoptosis in HEL cells. International Journal of Oncology 28 201-207 Legler DF, Micheau O, Doucey MA, Tschopp J and Bron C (2003) Recruitment of TNF receptor 1 to lipid rafts is essential for TNFa-mediated NF-kB activation. Immunity 18 655-664
Legrand-Poels
S, Bours V, Piret B, Pflaum M, Epe B, Rentier B and Piette J (1995)
Transcription factor NF-kB is activated by photosensitization generative
oxidative DNA damage. Journal of Biological Chemistry 270 6925-6934 Legrand-Poels S, Kustermans G, Bex F, Kremmer E, Kufer TA and Piette J (2007) Modulation of Nod2-dependent NF-kB signaling by the actin cytoskeleton. Journal of Cell Science in press Legrand-Poels
S, Schoonbroodt S, Matroule J-Y and Piette J (1998) NF-kB: an important
transcription factor in photobiology. Journal of Photochemistry and
Photobiology 45 1-8 Legssyer R, Josse C, Piette J, Ward RJ and Crichton RR (2003) Changes in function of iron-loaded alveolar macrophages after in vivo administration of desferrioxamine and/or chloroquine. Journal of Inorganic Biochemistry 94 36-42 Lehmann M,
Jiang C, Ip YT and Thummel CS (2002) AP-1, but not NF-kB, is required for
efficient steroid-triggered cell death in Drosophila. Cell Death and Differentiation 9
581-590 Lehmann T, Murphy C, Zahra DG and Handel ML (2002) Reduction of tumor necrosis factor induced nuclear factor-kB nuclear translocation and DNA binding by dexamethasone in human osteoarthritic synovial tissue explants. Journal of Rheumatology 29 787-795 Lehmann TG, Wheeler MD, Froh M, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA and Thurman RG (2003) Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. Transplantation 76 28-37 Lehming N,
McGuire S, Brickman JM and Ptashne M (1995) Interactions of a Rel protein with
its inhibitor. Proceedings of the National Academy of Sciences USA 92
10242-10246 Lehming N,
Thanos D, Brickman JM, Ma J, Maniatis T and Ptashne M (1994) An HMG-like
protein that can switch a transcriptional activator to a repressor. Nature 371
175-179
Lehnhardt A, Mengel M, Pape L, Ehrich JH, Offner G and Strehlau J (2006)
Nodular B-cell aggregates associated with treatment refractory renal
transplant rejection resolved by rituximab. Lehoux G, Le Gouill C, Stankova J and Rola-Pleszczynski M (2003) Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes. Mediators of Inflammation 12 29-35 Lehoux S and Tedgui A (2003) All strain, no gain: stretch keeps proliferation at bay via the NF-kB response gene iex-1. Circulation Research 93 1139-1141 Lehrke M, Millington SC, Lefterova M, Cumaranatunge RG, Szapary P, Wilensky R, Rader DJ, Lazar MA and Reilly MP (2007) CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans. Journal of the American College of Cardiology 49 442-449 Lehrke M, Reilly MP, Millington SC, Iqbal N, Rader DJ and Lazar MA (2004) An inflammatory cascade leading to hyperresistinemia in humans. PLoS Medicine 1 e45 Lehtonen A, Veckman V, Nikula T, Lahesmaa R, Kinnunen L, Matikainen S and Julkunen I (2005) Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages. Journal of Immunology 175 6570-6579 Lei FF, Zhao JX, Wang XX, Yao BT and Ding K (2007) Study on depressant effects of THPS on S180 tumor-bearing-mice and its mechanisms [Article in Chinese]. Zhong Ya Cai 30 1548-1551 Lei HY and Zhao XL (2007) Clinical significance of NF-kB continual activity and expression of WT1 and MDR1 in acute nonlymphocytic leukemia [Article in Chinese]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15 253-257 Leiba M, Cahalon L, SHimoni A, LIder O, Zanin-Zhorov A, Hecht I, Sela U, Vlodavsky I and Nagler A (2006) Halofuginone inhibits NF-kB and p38 MAPK in activated T cells. Journal of Leukocyte Biology in press Leidner J, Palkowitsch L, Marienfeld U, Fischer D and Marienfeld R (2008) Identification of lysine residues critical for the transcriptional activity and poly-ubiquitination of the NF-kB family member RelB. Biochemical Journal in press Leigh R, Oyelusi W, Wiehler S, Koetzler R, Zaheer RS, Newton R and Proud D (2008) Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling. Journal of Allergy and Clinical Immunology in press Leiro J, Arranz JA, Fraiz N, Sanmartin ML, Quezada E and Orallo F (2005) Effect of cis-resveratrol on genes involved in nuclear factor kB signaling. International Immunopharmacology 5 393-406 Leiro J, Arranz JA, Yanez M, Ubeira FM, Sanmartin ML and Orallo F (2004) Expression profiles of genes involved in the mouse nuclear factor-kB signal transduction pathway are modulated by mangiferin. International Immunopharmacology 4 763-778 Leiro J, Garcia D, Arranz JA, Delgado R and Sanmartin ML and Orallo F (2004) An Anacardiaceae preparation reduces the expression of inflammation-related genes in murine macrophages. International Immunopharmacology 4 991-1003 Leis H, Page A, Ramirez A, Bravo A, Segrelles C, Paramio J, Barettino D, Jorcano JL and Perez P (2003) Glucocorticoid Receptor counteracts tumorigenic activity of Akt in skin through interference with the phosphatidylinositol 3-kinase (PI3K) signaling pathway. Molecular Endocrinology 18 303-311 Leis H, Sanchis A and Perez P (2006) Deletion of the N-terminus of IKKg induces apoptosis in keratinocytes and impairs the AKT/PTEN signaling pathway. Experimental Cell Research in press Leitges M,
Sanz L, Martin P, Duran A, Braun U, Garcia JF, Camacho F, Diaz-Meco MT,
Rennert PD and Moscat J (2001) Targeted disruption of the zetaPKC gene results
in the impairment of the NF-kB pathway. Molecular Cell 8 771-780 Leitinger N, Huber J, Rizza C, Mechtcheriakova D, Bochkov V, Koshelnick Y, Berliner JA and Binder BR (2001) The isoprostane 8-iso-PGF(2alpha) stimulates endothelial cells to bind monocytes: differences from thromboxane-mediated endothelial activation. FASEB Journal 15 1254-1256 Leiva M, Ruiz-Breavo A, Moreno E and Jimenez-Valera M (2008) Telithromycin inhibits the production of proinflammatory mediators and the activation of NF-kB in in vitro-stimulated murine cells. FEMS Immunology and Medical Microbiology in press Leleu X, Eeckhoute J, Jia X, Roccaro AM, Moreau AS, Farag M, Sacco A, Ngo HT, Runnels J, Melham MR, Burwick N, Azab A, Azab F, Hunter Z, Hatjiharissi E, Carrasco DR, Treon SP, Witzip TE, Hideshima T, Brown M, Anderson KC and Ghobrial IM (2008) Targeting NF-kB in Waldenstrom macroglobulinemia. Blood in press Lelkes PI,
Hahn KL, Sukovich DA, Karmiol S and Schmidt DH (1998) On the possible role of
reactive oxygen species in angiogenesis. Adv Exp Med Biol 454 295-310 Lemarie CA, Tharaux PL, Esposito B, Tedgui A and Lehoux S (2006) Transforming growth factor-a mediates nuclear factor kB activation in strained arteries. Circulation Research in press Lemaitre B,
Nicolas E, Michaut L, Reichart J-M and Hoffmann JA (1996) The dorsoventral
regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal
response in Drosophila adults. Cell 86 973-983 Lemaitre B,
Reichhart J-M and Hoffman JA (1997) Drosophila host defense: Differential
induction of antimicrobial peptide genes after infection by various classes of
microorganisms. Proceedings of the National Academy of Sciences USA 94
14614-14619 Lemarie A, Lagadic-Gossmann D, Morzadec C, Allain N, Fardel O and Vernhet L (2004) Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor. Free Radic Biol Med 36 1517-1531 LeMarie A, Morzadec C, Merino D, Micheau O, Fardel O and Vernhet L (2005) Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through NF-kB-related survival pathway downregulation. J Pharmacol Exp Ther in press Lemarie CA, Esposito B, Tedgui A and Lehoux S (2003) Pressure-induced vascular activation of Nuclear Factor-kB. Role in cell survival. Circulation Research 93 207-212 Lemay S,
Lebedeva TV and Singh AK (1999) Inhibition of cytokine gene expression by
sodium salicylate in a macrophage cell line through an NF-kB-independent
mechanism. Clin Diagn Lab Immunol 6 567-572 Lemieux AM, Pare ME, Audet B, Legault E, Lefort S, Boucher N, Landry S, van Opijnen T, Berkhout B, Naghavi MH, Tremblay MJ and Barbeau B (2004) T cell activation leads to poor activation of HIV-1 clade E LTR and weak association of NF-kB and NFAT to its enhancer region. Journal of Biological Chemistry 279 52949-52960 Lemaout C, Gonzalez H, Aboab J and Annane D (2006) Pathophysiology of septic shock [Article in French]. Presse Med 35 521-527 Lemmers B, Salmena L, Bidere N, Su H, Matysiak-Zablocki E, Murakami K, Ohashi PS, Jurisicova A, Lenardo M, Hakem R and Hakem A (2007) Essenital role fo caspase-8 in Toll-like receptors and NFkB signaling. Journal of Biological Chemistry 282 7416-7423 Lemster BH, Michel JJ, Montag DT, Paat JJ, Studenski SA, Newman AB and Vallejo AN (2008) Induction of CD56 and TCR-independent activation of T cells with aging. Journal of Immunology 180 1979-1990 Lenardo M and
Baltimore D (1989) NF-kB: a pleiotropic mediator of inducible and
tissue-specific gene control. Cell 58 227-229 Lenardo M and
Siebenlist U (1994) Bcl-3-mediated nuclear regulation of the NF-kB trans-activating
factor. Immunology Today 15 145-147 Lenardo MJ, Fan CM, Maniatis T and Baltimore D (1989) The involvement of NF-kB in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 57 287-294 Lenardo MJ, Kuang A, Gifford A and Baltimore D 91989) Purified bovine NF-kB recognizes regulatory sequences in multiple genes expressed during activation of T- and B-lymphocytes. Hamatol Bluttransfus 32 411-415 Lenardo MJ, Kuang A, Gifford A and Baltimore D (1988) NF-kB protein purification from bovine spleen: nucleotide stimulation and binding site specificity. Proceedings of the National Academy of Sciences USA 85 8825-8829
Lenardo N,
Pierce JW and Baltimore D (1988) Protein-binding sites in Ig gene enhancers
determine transcriptional activity and inducibility. Science 236 1573-1577 Lendemans S, Rani M, Selbach C, Kreuzfelder E, Schade FU and Flohe S (2006) GM-CSF priming of human monocytes is dependent on ERK1/2 activation. Journal of Endotoxin Research 12 10-20 Lenert P, Goeken AJ and Ashman RF (2006) Extended sequence preferences for oligodeoxyribonucleotide activity. Immunology 117 474-481 Lenert P,
Stunz L, YI AK, Krieg AM and Ashman RFCpG stimulation of primary mouse B cells
is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kB
activation. Antisense Nucleic Acid Drug Development 11 247-256 Lenhard JM
and Gottschalk WK (2002) Preclinical developments in type 2 diabetes. Advances
in Drug Delivery Reviews 54 1199 Lentsch AB (2005) Activation and function of hepatocyte NF-kB in postischemic liver injury. Hepatology 42 216-218 Lentsch AB
and Ward PA (1999) Activation and regulation of NFkB during acute
inflammation. Clin Chem Lab Med 37 205-208 Lentsch AB,
Crouch LD, Jordan JA, Czermak BJ, Yun EC, Guo R, Sarma V, Diehl KM and Ward PA
(1999) Regulatory effects of interleukin-11 during acute lung inflammatory
injury. Journal of Leukocyte Biology 66 151-157 Lentsch AB,
Czermak BJ, Bless NM, Van Rooijen N and Ward PA (1999) Essential role of
alveolar macrophages in intrapulmonary activation of NF-kB. American Journal
of Respiratory Cell and Molecular Biology 20 692-698 Lentsch AB,
Czermak BJ, Jordan JA and Ward PA (1999) Regulation of acute lung inflammatory
injury by endogenous IL-13. Journal of Immunology 162 1071-1076 Lentsch AB,
Jordan JA, Czermak BJ, Diehl KM, Younkin EM, Sarma V and Ward PA (1999)
Inhibition of NF-kB activation and augmentation of IkBb by secretory
leukocyte protease inhibitor during lung inflammation. American Journal of
Pathology 154 239-247 Lentsch AB,
Kato A, Davis B, Wang W, Chao C and Edwards MJ (2001) STAT4 and STAT6 regulate
systemic inflammation and protect against lethal endotoxemia. Journal of
Clinical Investigation 108 1475-1482 Lentsch AB, Pathrose P, Kader S, Kuboki S, Collins MH and Waltz SE (2007) The Ron receptor tyrosine kinase regualtes acute lung injury and suppresses nuclear factor kB activation. Shock 27 274-280 Lentsch AB,
Shanley TP, Sarma V and Ward PA (1997) In vivo suppression of nuclear factor
kB and preservation of IkBa by interleukin-10 and interleukin-3. Journal of
Clinical Investigation 100 2443-2448 Lentsch AB, Yoshidome H, Warner RL, Ward PA and Edwards MJ (1999) Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion. Gastroenterology 117 953-961 Lentschat A, Karahashi H, Michelsen KS, Thomas LS, Zhang W, Vogel SN and Arditi M (2005) Mastoparan, a G protein agonist peptide, differentially modulates TLR4- and TLR2-mediated signaling in human endothelial cells and murine macrophages. Journal of Immunology 17 4252-4261 Lenz G, Davis RE, Ngo VN, Lam L, George TC, Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RJ, Chan WC and Staudt LM (2008) Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. Science in press Lenz HJ (2003) Clinical update: proteasome inhibitors in solid tumors. Cancer Treatment Reviews 29 Suppl 1 41-48
Leo E,
Deveraux Q, Buchholtz C, Welsh K, Matsuzawa S, Stennicke H, Salvesen GS and
Reed JC (2000) TRAF1 is a substrate of caspases activated during tumor
necrosis factor receptor-a induced apoptosis. Journal of Biological Chemistry
276 8087-8093 Leo E, Welsh
K, Matsuzawa S, Zapata JM, Kitada S, Mitchell RS, Ely KR and Reed JC (1999)
Differential requirements for tumor necrosis factor receptor-associated factor
family proteins in CD40-mediated induction of NF-kB and Jun N-terminal kinase
activation. Journal of Biological Chemistry 274 22414-22422 Leonard J,
Parrott C, Buckler-White AJ et al (1989) The NF-kB binding sites in the human
immunodeficiency virus type 1 long terminal repeat are not required for virus
infectivity. Journal of Virology 63 4919-4924 Leonard SS, Harris GK and Shi X (2004) Metal-induced oxidative stress and signal transduction. Free Radic Biol Med 37 1921-1942 Leonard SS, Roberts JR, Antonini JM, Castranova V and Shi X (2004) PbCrO4 mediates cellular responses via reactive oxygen species. Molecular and Cellular Biochemistry 255 171-179 Leonard SS, Wang S, Shi X, Jordan BS, Castranova V and Dubick MA (2000) Wood smoke particles generate free radicals and cause lipid peroxidation, DNA damage, NFkB activation and TNF-a release in macrophages. Toxicology 150 147-157 Leonard SS, Xia C, Jiang BH, Stinefelt B, Klandorf H, Harris GK and Shi X (2003) Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochemical and Biophysical Research Communications 309 1017-1026 Leonardi A,
Ellinger-Ziegelbauer H, Franzoso G, Brown K and Siebenlist U (2000) Physical
and functional interaction of filamin (actin-binding protein-280) and tumor
necrosis factor receptor-associated factor 2. Journal of Biological Chemistry
275 271-278 Leonardi A,
Vito P, Mauro C, Pacifico F, Ulianich L, Consiglio E, Formisano S and Di Jeso
B (2002) Endoplasmic reticulum stress causes thyroglobulin retention in this
organelle and triggers activation of nuclear factor-kB via tumor necrosis
factor receptor-associated factor 2. Endocrinology 143 2169-2177 Leonarduzzi G, Gamba P, Sottero B, Kadl A, Robbesyn F, Calogero RA, Biasi F, Chiarpotto E, Leitinger N, Sevanian A and Poli G (2005) Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells. Free Radical Biology and Medicine 39 1152-1161 Leonarduzzi G, Robbesyn F and Poli G (2004) Signaling kinases modulated by 4-hydroxynonenal. Free Radical Biology & Medicine 37 1694-1702 Leone MJ, Marpegan L, Bekinschtein TA, Costas MA and Golombek DA (2006) Suprachiasmatic astrocytes as an interface for immune-circadian signalling. Journal of Neuroscience Research 84 1521-1527
LePage C,
Popescu O, Genin P, Lian J, Paquin A, Galipeau J, Hiscott J (2001) Disruption
of NF-kB signaling and chemokine gene activation by retroviral mediated
espression of IKKy/NEMO mutants. Virology 286 422-433 Leppert BJ, Mansfield JM and Paulnock DM (20070 The soluble variant surface glycoprotein of African trypanosomes is recognized by a macrophage scavenger receptor and induces IkBa degradation independently of TRAF6-mediated TLR signaling. Journal of Immunology 179 548-556 Lerma E, Peiro G, Ramon T, Fernandez S,Martinez D, Pons C, Munoz F, Sabate JM, Alonso C, Ojeda B, Prat J and Barnadas A (2007) Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas). Modern Pathology in press Lernbecher T,
Müller U and Wirth T (1993) Distinct NF-kB/Rel transcription factors are
responsible for tissue-specific and inducible gene activation. Nature 365
767-770 Lerner CG,
Horton MR, Schwartz RH and Powell JD (2000) Distinct requirements for C-C
chemokine and IL-2 production by naive, previously activated, and anergic T
cells. Journal of Immunology 164 3996-4002 Lerner-Marmarosh N, Miralem T, Gibbs PE and Maines MD (2007) Regulation of TNF-a-activated PKC-{zeta} signaling by the human biliverdin reductase: Identification of activating and inhibitory domains of the reductase. FASEB Journal in press Lerner-Marmarosh N, Yoshizumi M, Che W, Surapisitchat J, Kawakatsu H, Akaike M, Ding B, Huang Q, Yan C, Berk BC and Abe JI (2003) Inhibition of tumor necrosis factor-a-Induced SHP-2 phosphatase activity by shear stress. A mechanism to reduce endothelial inflammation. Arteriosclerosis, Thrombosis and Vascular Biology 23 1775-1781 Lerner-Natoli M, Montpied P, Rousset MC, Bockaert J and Rondouin G (2000) Sequential expression of surface antigens and transcription factor NFkB by hippocampal cells in excitotoxicity and experimental epilepsy. Epilepsy Research 41 141-154 Lesage D, Metelev V, Borisova O, Dolinnaya N, Oretskaya T, Baran-Marszak F, Taillandier E, Raphael M and Fagard R (2003) Specific covalent binding of a NF-kB decoy hairpin oligonucleotide targeted to the p50 subunit and induction of apoptosis. FEBS Letters 547 115-118 Lesiak K, Sztiller-Sikorska M and Czyz M (2007) Transcription factors in the development and progression of melanoma. Postepy Hig Med Dosw 61 576-595 Leskinen MJ, Heikkila HM, Speer MY, Hakala JK, Laine M, Kovanen PT and Lindstedt KA (2006) Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-kB-mediated survival signaling. Experimental Cell Research in press Lesley R, Xu Y, Kalled SL, Hess DM, Schwab SR, Shu HB and Cyster JG (2004) Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity 20 441-453 Leslie M (2004) Ironing out cell death. Sci Aging Knowledge Environ (46) nf102 Lesner A, Li Y, Nitkiewicz J, Li G, Kartvelishvili A, Kartvelishvili M and Simm M (2005) A soluble factor secreted by an HIV-1-resistant cell line blocks transcription through inactivating the DNA-binding capacity of the NF-kB p65/p50 dimer. Journal of Immunology 175 2548-2554 Lessard L, Begin LR, Gleave ME, Mes-Masson AM, and Saad F (2005) Nuclear localisation of nuclear factor-kB transcription factors in prostate cancer: an immunohistochemical study. British Journal of Cancer 93 1019-1023 Lessard L, Karakiewicz PI, Bellon-Gagnon P, Alam-Fahmy M, Ismail HA, Mes-Masson AM and Saad F (2006) Nuclear localization of nuclear factor-kB p65 in primary prostate tumors is highly predictive of pelvic lymph node metastases. Clinical Cancer Research 12 5741-5745 Lessard L, Mes-Masson AM and Saad F (2006) NFkB; a new marker capable of predicting prostate cancer oucome. Bulletin of Cancer 93 891-899 Lessard L, Saad F, Le Page C, Diallo JS, Peant B, Delvoye N and mes-Masson AM (2007) NF-kB2 processing and p52 nuclear accumulation after androgenic stimulation of LNCaP prostate cancer cells. Cellular Signaling in press Letiembre M, Echchannaoui H, Ferracin F, Rivest S and Landmann R (2005) Toll-like receptor-2 deficiency is associated with enhanced brain TNF gene expression during pneumococcal meningitis. Journal of Neuroimmunology 168 21-33 Letoha
T, Feher LZ, Pecze L, Somlai C, Varga I, Kaxzaki J, Toth G, Vizler C,
Tiszlavica L and Takacs T (2007) Therapeutic proteasome inhibition in
experimental acute pancreatitis. Letoha T, Kusz E, Papai G, Szabolcs A, Kaszaki J, Varga I, Takacs T, Penke B and Duda E (2006) In vitro and in vivo NF-kB inhibitory effects of the cell-penetrating penetratin peptide. Molecular Pharmacology in press Letoha T, Somlai C, Takacs T, Szabolcs A, Jarmay K, Rakonczay-Jr Z, Hegyi P, Varga I, Kaszaki J, Krizbai I, Boros I, Duda E, Kusz E and Penke B (2005) A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis. World Journal of Gastroenterology 11 990-999 Letoha T, Somlai C, Takacs T, Szabolcs A, Rakonczay Jr Z, Jarmay K, Slalontai T, Varga I, Kaszaki J, Boros I, Duda E, Hackler L, Kurucz I and Penke B The proteasome inhibitor MG132 protects against acute pancreatitis. Free Radic Biol Med 39 1142-1151 Leu TH and Maa MC (2003) The molecular mechanisms for the antitumorigenic effect of curcumin. Curr Med Chem Anti-Cancer Agents 2 357-370 Leuenroth SJ and Crews CM (2008) Triptolide-induced transcriptional arrest is associated with changes in nuclear substructure. Cancer Research 68 5257-5266 Leulier F, Lhocine N, Lemaitre B and Meier P (2006) The Drosophila IAP DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection. Molecular and Cellular Biology in press Leulier F, Marchal C, Miletich I, Limbourg-Bouchon B, Benarous R and Lemaitre B (2003) Directed expression of the HIV-1 accessory protein Vpu in Drosophila fat-body cells inhibits Toll-dependent immune responses. EMBO Reports 4 976-981
Leulier F,
Vidal S, Saigo K, Ueda R and Lemaitre B (2002) Inducible expression of
double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults. Current Biology 12 996-1000 Leung CH, Grill SP, Lam W, Han QB, Sun HD and Cheng YC (2005) Novel mechanism of inhibition of NF-kB DNA-binding activity by diterpenoids isolated from Isodon rubescens. Molecular Pharmacology 68 286-297 Leung CH, Grill SP, Lam W, Gao W, Sun HD and Cheng YC (2006) Eriocalyxin B inhibits NF-kB activation by interfereing with the binding of both p65 and p50 to the response element in a non-competitive manner. Molecular Pharmacology in press Leung CY, Liu L, Wong RN, Zeng YY, Li M and Zhou H (2005) Saikosaponin-d inhibits T cell activation through the modulation of PKCtheta, JNK, and NF-kB transcription factor. Biochemical and Biophysical Research Communications in press Leung JC, Tang SC, Chan LY, Chan WL and Lai KN (2007) Synthesis of TNF-a by mesangial cells cultured with polymeric anionic IgA role of MAPK and NF-kB. Nephrology, Dialysis, Transplantation in press Leung JY, Chapman JA, Harris JA, Hale D, Chung RS, West AK and Chuah MI (2008) Olfactory ensheathing cells are attracted to, and can endocytose, bacteria. Cell and Molecular Life Sciences in press
Leung K and Nabel G (1988) HTLV-1 transactivator induces
interleukin-2 receptor through an
NF-kB-like factor. Nature 333 776-778 Leung TH, Hoffmann A and Baltimore D (2004) One nucleotide in a kB site can determine cofactor specificity for NF-kB dimers. Cell 118 453-464 Leung TM, Tipoe Gl, Liong EC, Lau TY, Fung ML and Nanji AA (2008) Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis. International Journal of Experimental Pathology in press Leurs R,
Church MK and Taglialatela M (2002) H1-antihistamines: inverse agonism,
anti-inflammatory actions and cardiac effects. Clin Exp Allergy 32 489-498 Lev DC, Ruiz M, Mills L, McGary EC, Price JE and Bar-Eli M (2003) Dacarbazine causes transcriptional up-regulation of interleukin 8 and vascular endothelial growth factor in melanoma cells: a possible escape mechanism from chemotherapy. Molecular Cancer Therapy 2 753-763 Léveillard T
and Verma IM (1993) Diverse molecular mechanisms of inhibition of NF-kB/DNA
binding complexes by IkB proteins. Gene Expression 3 135-150 Levenson JM, Choi S, Lee SY, Cao YA, Ahn HJ, Worley KC, Pizzi M, Liou HC and Sweatt JD (2004) A bioinformatics analysis of memory consolidation reveals involvement of the transcription factor c-Rel. Journal of Neuroscience 24 3933-3943 Leverkus M, Diessenbacher P and Geserick P (2008) FLIP ing the coin? Death receptor-mediated signals during skin tumorigenesis. Experimental Dermatology 17 614-622 Leverkus M, Sprick MR, Wachter T, Denk A, Brocker EB, Walczak H and Neumann M (2003) TRAIL-induced apoptosis and gene induction in HaCaT keratinocytes: differential contribution of TRAIL receptors 1 and 2. Journal of Investigative Dermatology 121 149-155 Leverkus M, Sprick MR, Wachter T, Mengling T, Baumann B, Serfling E, Brocker EB, Goebeler M, Neumann M and Walczak H (2003) Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation. Molecular and Cellular Biology 23 777-790
Levi E,
Pfeifer WM and Kadin ME (2001) CD30-activation-mediated growth inhibition of
anaplastic large-cell lymphoma cell lines: apoptosis or cell-cycle arrest?
Blood 98 1630-1632 Levidou G, Saetta AA, Korkolopoulou P, Papanastasiou P, Gioti K, Pavlopoulos P, Diamantopoulou K, Thomas-Tsagli E, Xiromeritis K and Patsouris E (2008) Clinical significance of nuclear factor (NF)-kB levels in urothelial carcinoma of the urinary bladder. Virchows Archiv in press Levine A, Karban A, Eliakim R, Shaoul R, Reif S, Pacht A, Wardi J, Yakir B and Silver EL (2005) A polymorphism in the TNF-a promoter gene is associated with pediatric onset and colonic location of Crohn's Disease. American Journal of Gastroenterology 100 407-413
Levine A,
Tenhaken R, Dixon R and Lamb C (1994) H2O2 from the oxidative burst
orchestrates the plant hypersensitive disease resistance response. Cell 79
583-593 Levine GK, Deutschman CS, Helfaer MA and Margulies SS (2006) Sepsis-induced lung injury in rats increases alveolar epithelial vulnerability to stretch. Critical Care Medicine in press Levine RA,
McDormack JE, Buckler A and Sonenshein GE (1986) Complex regulation of c-myc
gene expression in a murine B cell lymphoma. Current Topics in Microbiology
and Immunology 132 305-312 Levites Y,
Youdim MB, Maor G and Mandel S (2002) Attenuation of 6-hydroxydopamine
(6-OHDA)-induced nuclear factor-kB (NF-kB) activation and cell death by tea
extracts in neuronal cultures. Biochemical Pharmacology 63 21-29 Levitsky VG, Ignatieva EV, Ananko EA, Turnaev II, Merkulova TK, Kolchanov NA and Hodgman TC (2007) Effective transcription factor binding site prediction using a combination of optimization, a genetic algorithm and discriminant analysis to capture distant interactions. BMC Bioinformatics in press Levkau B,
Garton KJ, Ferri N, Kloke K, Nofer JR, Baba HA, Raines EW and Breithardt G
(2001) xIAP induces cell-cycle arrest and activates nuclear factor-kB : new
survival pathways disabled by caspase-mediated cleavage during apoptosis of
human endothelial cells. Circulation Research 88 282-290 Levkau B,
Scatena M, Giachelli CM, Ross R and Raines EW (1999) Apoptosis overrides
survival signals through a caspase-mediated dominant-negative NF-kB loop. Nature Cell Biology 1 227-233 Levrand S, Pesse B, Feihl F, Waeber B, Pacher P, Rolli J, Schaller MD and Liaudet L (2005) Peroxynitrite is a potent inhibitor of NF-kB activation triggered by inflammatory stimuli in cardiac and endothelial cell lines. Journal of Biological Chemistry 280 34878-34887 Levy DE, Marie I I and Prakash A (2002) Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity. Current Opinion in Immunology 15 52-58 Levy O, Suter EE, Miller RL and Wessels MR (2006) Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood 108 1284-1290 Levy P, Robin H, Bertrand F, Kornprobst M and Capeau J (2003) Butyrate-treated colonic Caco-2 cells exhibit defective integrin-mediated signaling together with increased apoptosis and differentiation. Journal of Cell Physiology 197 336-347 Levy RM, MOllen KP, Prince JM, Kaczorowski DJ, Vallabhaneni R, Liu S, Tracey KJ, Lotze MT, Hackam DJ, Fink MP, Vodovotz Y and Billiar TR (2007) Systemic inflammation and remote organ injury following trauma require HMGB1. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology in press Levy RM, Prince JM, Yang R, Mollen KP, Liao H, Watson GA, Fink MP, Vodovotz Y and Billiar TR (2006) Systemic inflammation and remote organ damage following bilateral femur fracture requires toll-like receptor 4. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 291 R970-R976
Lewin B
(1990) Oncogenic conversion by regulatory changes in transcription factors.
Cell 64 303-312 Lewis AJ and
Manning AM (1999) New targets for anti-inflammatory drugs. Current Opinions in
Chemistry and Biology
3 489-494 Lewis CC, Yang JY, Huang X, Banerjee SK, Blackbrun MR, Baluk P, McDonald DM, Blackwell TS, Nagabhushanam V, Peters W, Voehringer D and Erle DJ (2007) Disease-specific gene expression profiling in multiple models of lung disease. American Journal of Respiratory Critical Care Medicine in press Lewis DA, Hengeltraub SF, Gao FC, Leivant MA and Spandau DF (2006) Aberrant NF-kB activity in HaCaT cells alters their response to UVB signaling. Journal of Investigative Dermatology 126 1885-1892 Lewis DA and Spandau DF (2007) UVB activation of NF-kB in normal human keratinocytes occurs via a unique mechanism. Archives of Dermatological Research 299 93-101 Lewis DA and Spandau DF (2007) UVB-induced activation of NF-kB is regulated by the IGF-1R and dependent on p38 MAPK. Journal of Investigative Dermatology in press Lewis H,
Kaszubska W, DeLemarter JF and Whelan J (1994) Cooperativity between two NF-kB
complexes, mediated by high-mobility-group protein I(Y), is essential for
cytokine-induced expression of the E-selectin promoter. Molecular and Cellular
Biology 14 5701-5709 Lewis J, Burstein E, Birkey Reffey S, Bratton SB, Roberts AB and Duckett CS (2004) Uncoupling of the signaling and caspase-inhibitory properties of XIAP. Journal of Biological Chemsitry 279 9023-9029 Lewis J,
Devin A, Miller A, Lin Y, Rodriguez Y, Neckers L and Liu ZG (2000) Disruption
of hsp90 function results in degradation of the death domain kinase,
receptor-interacting protein (RIP), and blockage of tumor necrosis
factor-induced nuclear factor-kB activation. Journal of Biological Chemistry
275 10519-10526 Lewis JB, Randol TM, Lockwood PE and Wataha JC (2003) Effect of subtoxic concentrations of metal ions on NFkB activation in THP-1 human monocytes. J Biomed Mater Res 64A 217-224 Lewis K, Caldwell J, PHan V, Prescott D, Nazli A< Wang A, Soderholm JD, Perdue MH, Sherman PM and McKay DM (2008) Decreased epithelial barrier function evoked by exposure to metabolic stress and non-pathogenic E. coli is enhanced by TNFa. American Journal of Physiology: Gastrointestinal and Liver Physiology in press
Lewis MJ,
Sheehy N, Salemi M, VanDamme A-M and Hall WW (2002) Comparison of CREB- and
NF-kB-mediated transactivation by Human T lymphotropic virus type II (HTLV-II)
and Type 1 (HTLV-I) Tax proteins. Virology 295 182-189 Lewis R,
McClure J, Rup B, Niesel DW, Garry RF, Hoelzer JD, Nazerian K and Bose Jr HR
(1981) Avian reticuloendotheliosis virus: identification of the hematopoietic
target cell for transformation. Cell 25 421-431 Lewis RS (2003) Calcium oscillations in T-cells: mechanisms and consequences for gene expression. Biochem Soc Trans 31 925-929 Leyva-Baca I, Schenkel F, Martin J and Karrow NA (2008) Polymorphisms in the 5' upstream region of the CXCR1 chemokine receptor gene, and their association with somatic cell score in Holstein cattle in Canada. Journal of Dairy Science 91 407-417
Lezoualch F,
Engert S, Berning B and Behl C (2000) Corticotropin-releasing hormone-mediated
neuroprotection against oxidative stress is associated with the increased
release of non-amyloidogenic amyloid beta precursor protein and with the
suppression of nuclear factor-kB. Molecular Endocrinology 14 147-159 Lgssiar A, Hassan M, Schott-Ohly P, Friesen N, Nicoletti F, Trepicchio WL and Gleichmann H (2004) Interleukin-11 inhibits NF-kB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice. Exp Biol Med (Maywood) 229 425-436 L'Heureux MC and Brubaker PL (2003) Glucagon-like Peptide-2 and common therapeutics in a murine model of ulcerative colitis. Journal of Pharmacology and Experimental Therapeutics 306 347-354 Li A, He M, Wang H, Qiao B, Chen P, Gu H, Zhang M and He S (2007) All-trans retinoic acid negatively regulates cytotoxic activities of natural killer cell line 92. Biochemical and Biophysical Research Communications 352 42-47 Li B, Zhang R, Li J, Zhang L, Deing G, Luo P, He S, Dong Y, Jiang W, Lu Y, Cao H, ZHeng J and ZHou H (2008) Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-kB activation. International Immunopharmacology 8 379-389 Li BG, Feng DY, Cheng RX, He QQ, Hu ZL, Zheng H and Wen JF (2005) The effects of hepatitis C virus core protein on biological behaviors of human hepatocytes [Article in Chinese]. Zhonghua Yi Xue Za Zhi 85 1243-1248 Li BA, Heng
Y, Hou J, Gao R, Li J, Zheng Y, Su Q and Fu TQ (2002) Sero-and molecular
epidemilogy of the gene of different ORF of transfusion transmitted virus (TTV)
in different population of China [Article in Chinese]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue
Za Zhi 16 79-81 Li C, Bardhan
S, Pace EA, Liang M-C, Gilmore TD and Porco JA Jr (2002) Angiogenesis
inhibitor epoxyquinol A: total synthesis and inhibition of transcription
factor NF-kB. Organic Letters 4 3267-3270 Li C, Browder
W and Kao RL (1999) Early activation of transcription factor NF-kB during
ischemia in perfused rat heart. American Journal of Physiology 276 H543-H552 Li C, Ha T, Kelley J, Gao X, Qiu Y, Kao RL, Browder W and Williams DL (2004) Modulating Toll-like receptor mediated signaling by (1-->3)-beta-d-glucan rapidly induces cardioprotection. Cardiovascular Research 61 538-547 Li C, Ha T,
Liu L, Browder W and Kao RL (2000) Adenosine prevents activation of
transcription factor NF-kB and enhances activator protein-1 binding activity
in ischemic rat heart. Surgery 127 161-169 Li C, Kao RL,
Ha T, Kelley J, Browder IW and Williams DL (2001) Early activation of IKKbeta
during in vivo myocardial ischemia. Am J Physiol Heart Circ Physiol 280
H1264-H1271 Li
C, Kelley J and Ha T (2005) Activation of nuclear factor-kB. Methods in
Molecular Biology 315 141-150 Li C, Norris PS, Ni CZ, Havert ML, Chiong EM, Tran BR, Cabezas E, Reed JC, Satterthwait AC, Ware CF and Ely KR (2003) Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for TRAF-mediated signaling. Journal of Biological Chemistry 278 50523-50529
Li C, Pace
EA, Liang M-C, Lobkovsky E, Gilmore TD and Porco Jr JA (2001) Total synthesis
of the NF-kB inhibitor (-)-cycloepoxydon: utilization of tartrate-mediated
nucleophilic exclusion. Journal of the American Chemical Society 123
11308-11309 Li C, Zhang Y, Liu Z, Yu M and Yu W (2008) Helicobacter pylori VacA up-regulates secretion of macrophages by transfection of VacA eukaryotic expression vector [Article in Chinese]. Wei Sheng Wu Xue Bao 48 349-354 Li CC, Chou CK, Wang MH and Tsai TF (2006) Overexpression of ABIN-2, a negative regulator of NF-kB, delays liver regeneration in the ABIN-2 transgenic mice. Biochemical and Biophysical Research Communications 342 300-309 Li CC, Xie ZX, Zhang YD, Chen JH and Yang Z (2003) Total synthesis of wedelolactone. Journal of Organic Chemistry 68 8500-8504 Li C-C H, Dai
R-M and Longo DL (1995) Inactivation of NF-kB inhibitor IkBa:
ubiquitin-dependent proteolysis and its degradation product. Biochemical and
Biophysical Research Communications 215 292-301 Li C-C H, Dai
R-M, Chen E and Longo DL (1994) Phosphorylation of NF-kB1-p50 is involved in
NF-kB activation and stable DNA binding. Journal of Biological Chemistry 269
30089-30092 Li C-C H,
Ruscetti FW, Rice NR, Chen E, Yang N-S, Mikovits J and Longo DL (1993)
Differential expression of Rel family members in human T-cell leukemia virus
type I-infected cells: transcriptional activation of c-rel by Tax protein.
Journal of Virology 67 4205-4213 Li C-CH,
Korner M, Ferris DK, Chen E, Dai R-M and Longo DL (1994) NF-kB/Rel family
proteins are physically associated phosphoproteins. Biochemical Journal 303
499-506 Li CH, Wang JH and Redmond HP (2006) Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation. Journal of Leukocyte Biology in press Li CJ, Dezube
BJ, Biswas DK, Ahlers CM and Pardee AB (1994) Inhibitors of HIV-1
transcription. Trends in Microbiology 2 164-169 Li CL, Wang
XY, Shao J, Zhang JS, Feng WG, Wang YB and Chang ZL (2002) Heat shock inhibits
IL-12 p40 expression through NF-kB signalling pathway in murine macrophages.
Cytokine 16 153-159 Li CY, Li L, Li YH, Ai HX and Zhang L (2005) Effects of extract from Cornus officinalis on nitric oxide and NF-kB in cortex of cerebral infarction rat model [Article in Chinese]. Zhongguo Zhong Yao Za Zhi 30 1667-1670 Li CY, Zhan YQ, Xu CW, Xu WX, Wang SY, Lv J, Zhou Y, Yue PB, Chen B and Yang XM (2004) EDAG regulates the proliferation and differentiation of hematopoietic cells and resists cell apoptosis through the activation of nuclear factor-kB. Cell Death & Differentiation 11 1299-1308 Li D (2006) Selective degradation of the IkappaB kinase (IKK) by autophagy. Cell Research 16 855-856 Li D and
Mehta JL (2000) Upregulation of endothelial receptor for oxidized LDL (LOX-1)
by oxidized LDL and implications in apoptosis of human coronary artery
endothelial cells: evidence from use of antisense LOX-1 mRNA and chemical
inhibitors. Arteriosclerosis, Thrombosis, Vascular Biology 20 1116-1122 Li D, Saldeen
T and Mehta JL (1999) gamma-tocopherol decreases ox-LDL-mediated activation of
nuclear factor-kB and apoptosis in human coronary artery endothelial cells.
Biochemical and Biophysical Research Communications 259 157-161 Li D and Taylor AW (2008) Diminishment of {alpha}-MSH anti-inflammatory activity in MC1r siRNA-transfected RAW264.7 macrophages. Journal of Leukocyte Biology in press Li DH, Kumanogoh A, Cao TM, Parnes JR and Cullen JM (2004) Woodchuck interleukin-6 gene: structure, characterization, and biologic activity. Gene 342 157-164 Li DH, Tung JW, Tarner IH, Snow AL, Yukinari T, Ngernmaneepothong R, Martinez OM and Parnes JR (2006) CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. Journal of Immunology 176 5321-5328 Li G, Aaron S, Kazmierczak K, Lesner A, Li Y, Ivanova A, Bentsman G, Potash MJ and SImm M (2007) Inhibition of HIV-1 or bacterial activation of macrophages by products of HIV-1-resistant human cells. Immunology and Cell Biology in press Li G, Dong B, Butz DE, Park Y, Pariza MW and Cook ME (2006) NF-kB independent inhibition of lipopolysaccharide-induced cyclooxygenase by a conjugated linoleic acid cognate, conjugated nonadecadienoic acid. Biochimica et Biophysica Acta 1761 969-972 Li G, Labruto F, Sirsjo A, Chen F, Vaage J and Valen G (2004) Myocardial protection by remote preconditioning: the role of nuclear factor kappa-B p105 and inducible nitric oxide synthase. European Journal of Cardiothoracic Surgery 26 968-973 Li G, Lubin FD and McGee DW (2004) alpha3beta1 integrin induced suppression of the Caco-2 epithelial cell IL-1 signaling pathway leading to NF-kB activation. Cellular Immunology 231 30-39 Li G, Luna C, Liton PB, Navarro I, Epstein DL and Gonzalez P (2007) Sustained stress response after oxidative stress in trabecular meshwork cells. Molecular Vision 13 2282-2288 Li G, Qi XP, Wu XY, Liu FK, Xu Z, Chen C, Yang XD, Sun Z and Li JS (2006) Verapamil modulates LPS-induced cytokine production via inhibition of NF-kB activation in the liver. Inflammation Research 55 108-113 Li GP, Liu ZG, Zhong NS, Liao B and Xiong Y (2006) Therapeutic effects of DNA vaccine on allergen-induced allergic airway inflammation in mouse model. Cellular & Molecular Immunology 3 379-384 Li H, Cai X, Fan X, Moquin B, Stoicov C and Houghton J (2007) Fas Ag/Fas L coupling leads to ERK 1/2 mediated proliferation of gastric mucosal cells. American Journal of Physiology: Gastrotinerinal Liver Physiology in press Li H, Chehade M, Liu W, Xiong H, Mayer L and Berin MC (2007) Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells. Gastroenterology 133 1905-1915 Li H, Cuartas E, Cui W, Choi Y, Crawford TD, Ke HZ, Kobayashi KS, Flavell RA and Vignery A (2005) IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. Journal of Experimental Medicine 201 1169-1177 Li H, Gao L, Shen Z, Li CY, Li K, Li M, Lv YJ, Li CX, Gao TW and Liu YF (2008) Association study of NFKB1 and SUMO4 polymorphisms in Chinese patients with psoriasis vulgaris. Archives of Dermatological Research in press Li H, Gu H and Sun B (2007) Protective effects of pyrrolidine dithiocarbamate on myocardium apoptosis induced by adriamycin in rats. International Journal of Cardiology 114 159-165 Li H, Kobayashi M, Blonska M, You Y and Lin X (2006) Ubiquitination of RIP is required for TNFa-induced NF-kB activation. Journal of Biological Chemistry 281 13636-13643 Li H, Li X, Duan L and Li C (2003) Inhibition of lovastatin on proliferation and expression of proinflammatory cytokines in cultured human glomerular mesangial cells. Chinese Medical Journal (English) 116 1366-1369 Li H and Lin X (2007) Positive and negative signaling components involved in TNFa-induced NF-kB activation. Cytokine in press Li H, Malhotra S and Kumar A (2008) Nuclear factor-kB signaling in skeletal muscle atrophy. Journal of Molecular Medicine in press Li H, Rajendran GK, Lin N, Ware C, Rubin BP and Gu Y (2007) SirT1 modulates the estrogen-IGF-1 signaling for postnatal development of mammary gland in mice. Breast Cancer Research 9 R1 Li H, Ren CP, Tan XJ, Yang XY, Zhang HB, Zhou W and Yao KT (2006) Identification of genes related to nasopharyngeal carcinoma with the help of pathway-based networks. Acta Biochimica Biophysica Sinica (Shanghai) 38 900-910 Li H, Ruan XZ, Powis SH, Fernando R, Mon WY, Wheeler DC, Moorhead JF and Varghese Z (2005) EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-g-dependent mechanism. Kidney International 67 867-874 Li H, Ye X, Mahanivong C, Bian D, Chun J and Huang S (2005) Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells. Journal of Biological Chemistry 280 10564-10571 Li H, Yin H,
Zhang H, Cao X, Wang Z and She M (2002) Effect of NF-kB on the induction of
PDGF-B transcription by angiotensin II in the ECV304 cell line. Chinese Medical
Journal (Engl)
115 433-438 Li H, Yin H,
Zhang H, Wang Z and She M (2001) Activation of NF-kB and its effect on
induction of platelet-derived growth factor-B transcription by angiotensin II
in ECV304 cell line [Article in Chinese]. Zhonghua Bing Li Xue Za Zhi 30
276-280 Li H, Zhang J, Kumar A, Zheng M, Atherton SS and Yu FS (2006) Herpes simplex virus 1 infection induces the expression of proinflammatory cytokines, interferons and TLR7 in human corneal epithelial cells. Immunology 117 167-176 Li H, Zhu Zl, Jia N, Bai ZL, Cai Q, Chen R, Song TB and Liu JK (2006) Gender-dependent difference of NF-kB expression in the hippocampus of prenatally stressed offspring rats [Article in Chinese]. Sheng Li Xue Bao 58 577-583 Li HJ, Yin H, Yao YY, Shen B, Bader M Chao L and Chao J (2006) Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation. Cardiovascular Research in press Li HL, Chen HL, Li H, Zhang KL, Chen XY, Wang XW, Kong QY and Liu J (2005) Regulatory effects of emodin on NF-kB activation and inflammatory cytokine expression in RAW 264.7 macrophages. International Journal of Molecular Medicine 16 41-47 Li HL, Huang Y, Zhang CN, Liu G, Wei YS, Wang AB, Liu YQ, Hui RT, Wei C, Williams GM, Liu DP and Liang CC (2006) Epigallocathechin-3 gallate inhibits cardiac hypoertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radical Biology and Medicine 40: 1756-1775 Li HL, Liu C, de Couto G, Ouzounian M, Sun M, Wang AB, Huang Y, He CW, Shi Y, Chen X, Nghiem MP, Liu Y, Chen M, Dawood F, Fukuoka M, Maekawa Y, Zhang L, Leask A, Ghosh AK, Kirschenbaum LAA and Liu PP (2008) Curcumin prevents and reverses murine cardiac hypertrophy. Journal of Clinical Investigation in press Li HL, Liu B, Zhou LW and Yu WH (2005) Change and significance of nuclear factor-kB in adriamycin induced cardiomyopathy in rats. Chinese Medical Journal (English) 118 111-115 Li HL, Wang AB, Huang Y, Liu DP, Wei C, Williams GM, Zhang CN, Liu G, Liu YQ, Hao DL, Hui RT, Lin M and Liang CC (2005) Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways. Free Radical Biology and Medicine 38 243-257 Li HL, Wang AB, Zhang R, Wei YS, Chen HZ, She ZG, Huang Y, Liu DP and Liang CC (2006) A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages. Journal of Cellular Physiology in press Li HL, Yin R, Chen D, Liu D, Wang D, Yang Q and Dong YG (2007) Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy. Journal of Cellular Biochemistry in press Li HM, Man C, Jin Y, Deng W, Yip YL, Feng HC, Cheung YS, Lo KW, Meltzer PS, Wu ZG, Kwong YL, Yuen AP and Tsao SW (2006) Molecular and cytogenetic changes involved in the immortalization of nasopharyngeal epithelial cells by telomerase. Interntational Journal of Cancer in press Li HM, Zhuang ZH, Wang Q, Pang JC, Wang XH, Wong HL, Feng HC, Jin DY, Ling MT, Wong YC, Eliopoulos AG, Young LS, Huang DP and Tsao SW (2004) Epstein-Barr virus latent membrane protein 1 (LMP1) upregulates Id1 expression in nasopharyngeal epithelial cells. Oncogene 23 4488-4494 Li HY, Liu H, Wang CH, Zhang JY, Man JH, Gao YF,, Zhang PJ, Li WH, Zhao J, Pan X, Zhou T, Gong WL, Li AL and Zhang XM (2008) Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1. Nature Immunology in press Li HZ, Cao JG, Deng YA, Su JH and Xie WY (2007) Induction of apoptosis of human ovarian cancer CoC1 cells by 5-allyl-7-gen-difluoromethylenechrysin through activation of peroxisome-proliferator activated receptor-gamma {Article in Chinese]. Zhonghua Yi Xue Za Zhi 87 2914-2918 Li J and
Brasier AR (1996) Angiotensinogen gene activation by angiotensin II is
mediated by the rel A (nuclear factor-kB p65) transcription factor: one
mechanism for the renin angiotensin system positive feedback loop in
hepatocytes. Molecular Endocrinology 10 252-264 Li J, Chen H, Ke Q, Feng Z, Tang MS, Liu B, Amin S, Costa M and Huang C (2004) Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kB in mouse epidermal cl41 cells. Molecular Carcinogenesis 40 104-115 Guo J, Guo M, Hu B, Liu R, Wang R and Tang C (2008) Does chronic ethanol intake cause chronic pancreatitis?: evidence and mechanism. Pancrease 37 189-195 Li J, Johnson XD, Iasvovskaia S, Tan A, Lin A and Hershenson MB (2002) Signaling intermediates required for NF-kB activation and IL-8 expression in CF bronchial epithelial cells. American Journal of Physiology: Lung Cellular and Molecular Physiology 284 L307-L315 Li J, Joo SH and Tsai MD (2003) An NF-kB-specific inhibitor, IkBa, binds to and inhibits cyclin-dependent kinase 4. Biochemistry 42 13476-13483 Li J, Kartha
S, Iasvovskaia S, Tan A, Bhat RK, Manaligod JM, Page K, Brasier AR and
Hershenson MB (2002) Regulation of human airway epithelial cell IL-8
expression by MAP kinases. American Journal of Physiology: Lung Cellular and Molecular Physiology 283 L690-L699 Li J, Li Q, Xie C, Zhou H, Wang Y, Zhang N, Shao H, Chan SC, Peng X, Lin SC and Han J (2004) beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death. Journal of Cell Science 117 4673-4680 Li J, Liu Z,
Jiang S, Cortesini R, Lederman S and Suciu-Foca N (1999) T suppressor
lymphocytes inhibit NF-kB-mediated transcription of CD86 gene in APC. Journal
of Immunology 163 6386-6392 Li J, Lu Z, Li WL, Yu SP and Wei L (2008) Cell death and proliferation in NF-kB p50 knockout mouse after cerebral ischemia. Brain Research in press Li J, Ma Z, Tang ZL, Stevens T, Pitt B and Li S (2004) CpG DNA-mediated immune response in pulmonary endothelial cells. American Journal of Physiology: Lung Cellular and Molecular Physiology 287 L552-558 Li J, Ma Z, Blythe SP and Castillo-Chavez C (2003) Coexistence of pathogens in sexually-transmitted disease models. Journal of Mathematical Biology 47 547-568 Li J, Minnich DJ, Camp ER, Brank A, Mackay SL and Hochwald SN (2006) Enhanced sensitivity to chemotherapy in esophageal cancer through inhibition of NF-kB. Journal of Surgical Research 11332 112-120 Li J, Moran T, Swanson E, Julian C, Harris J, Bonen DK, Hedl M, Nicolae DL, Abraham C and Cho JH (2004) Regulation of IL-8 and IL-1{beta} expression in Crohn's disease associated NOD2/CARD15 mutations. Human Molecular Genetics 13 1715-1725 Li J, Peet GW,
Balzarano D, Li X, Massa P, Barton RW and Marcu KB (2001) Novel NEMO/IkB kinase
and NF-kB target genes at the pre-B to immature B cell transition. Journal of
Biological Chemistry 276 18579-18590 Li J, Quan N and Bray TM (2002) Supplementation of N-acetylcysteine normalizes lipopolysaccharide-induced nuclear factor kappaB activation and proinflammatory cytokine production during early rehabilitation of protein malnourished mice. Journal of Nutrition 132 3286-3292 Li
J, Shen J adn Beurman RW (2007) Expression of toll-like receptors in human
limbal and conjunctival epithelial cells. Li J, Vesey DA, Johnson DW and Gobe G (2007) Erythropoietin reduces cisplatin-induced apoptosis in renal carcinoma cells via a PKC dependent pathway. Cancer Biology Therapeutics in press Li J, Wu M, Que L, Wang Y, Xu X< Hu Y, Ha T, Li C, Chen Q and Li Y (2008) 17beta-estradiol attenuates cardiac dysfunction and decreases NF-kB binding activity in mechanically stretched rat hearts. Steroids in press Li
J, Zelenin S, Aperia A and Aizman O (2006) Low doses of ouabain protect from
serum deprivation-triggered apoptosis and stimulate kidney cell proliferation
via activation of NF-kB. Li J, Zhang D, Stoner GD and Huang C (2007) Differential effects of black raspberry and strawberry extracts on BaPDE-induced activation of transcription factors and their target genes. Molecular Carcinogenesis in press Li J, Zhou H,
Cai Q and Xiao G (2002) Activation of NF-kB and apoptosis of intestinal
epithelial cells induced by hydrogen peroxide. Chinese Journal of Traumatology
5 209-213 Li J, Zuo L, Shen T and Zhang ZN (2002) Inhibition of the activation of transcriptional factor NFkB during sodium selenite-induced apoptosis in NB4 cells {Article in Chinese]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 10 409-412 Li JC, Chang L, Lu D, Jiang DJ and Tan DM (2007) Effect of asymmetric dimethylarginine on the activation of hepatic stellate cells and its mechanism [Article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue B 32 427-432 Li JD (2003) Exploitation of host epithelial signaling networks by respiratory bacterial pathogens. Journal of Pharmacological Sciences 91 1-7 Li JG, Hu ZF, Du ZH, Zhou Q, Jia BH, Peng ZQ, Ye XF and Li B (2005) Protective effect of the cholinergic anti-inflammatory pathway against hemorrhagic shock in rats [Article in Chinese]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 17 24-27 Li JH, Kirkiles-Smith NC, McNiff JM and Pober JS (2003) TRAIL induces apoptosis and inflammatory gene expression in human endothelial cells. Journal of Immunology 171 1526-1533 Li JH, Yu JP, Yu HG, Xu XM, Yu LL and Liu SQ (2005) Expression and significance of nuclear factor kB p65 in colon tissues of rats with TNBS-induced colitis. World Journal of Gastroenterology 11 1759-1763
Li JH, Yu JP, Yu HG, Xu XM, Yu LL, Liu J and Luo HS (2005)
Melatonin reduces inflammatory injury through inhibiting NF-kB activation in
rats with colitis. Mediators of Inflammation
2005 185-193 Li JJ and Gao RL (2005) Should atherosclerosis be considered a cancer of the vascular wall? Medical Hypotheses 64 694-698
Li JJ, Oberly
LW, Fan M and Colburn NH (1998) Inhibition of AP-1 and NF-kB by
manganese-containing superoxide dismutase in human breast cancer cells. FASEB
Journal 12 1713-1723 Li JJ, Rhim JS, Schlegel R, Vousden KH and Colburn NH (1998) Expression of dominant negative Jun inhibits elevated AP-1 and NF-kB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes. Oncogene 16 2711-2721 Li JL, Chen HM, Li ML, Hua D, Lu ZH and Wang JK (2006) An optimized assay for transcription factor NF-kB with dsDNA-coupled microplate. Colloids and Surfaces. B, Biointerfaces 55 31-37
Li J-M, Shen
X, Hu PP-C and Wang X-F (1998) Transforming growth factor b stimulates the
human immunodeficiency virus 1 enhancer and requires NF-kB activity. Molecular
and Cellular Biology 18 110-121 Li JY, Lai YJ, Yeh HI, CHen CL, Sun S, Wu SJ and Lin FY (2008) Atrial gap junctions, NF-kB and fibrosis in patients undergoing coronary artery bypass surgery: the relationship with postoperative atrial fibrillation. Cardiology 112 81-88 Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M Jr and Lemon SM (2005) Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proceedings of the National Academy of Sciences USA in press Li KL, Zhang JG, Wang HM and Chen J (2004) The effects of glycyrrhizin-18alpha on the expression of NF-kB in the renal interstitium of rats with obstructive nephropathy [Article in Chinese]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20 31-33 Li L (2004) Regulation of innate immunity signaling and its connection with human diseases. Current Drug Targets in Inflammation and Allergy 3 81-86 Li L, Aggarwal BB, Shishodia S, Abbruzzese J and Kurzrock R (2004) Nuclear factor-kB and IkB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer 101 2351-2362 Li L, Asterious T, Bernert B, Heldin CH and Heldin P (20070 Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: Importance of hyaluronan for the mitogenic response of PDGF-BB. Biochemical Journal in press Li L, Bin LH, Li F, Liu Y, Chen D, Zhai Z and Shu HB (2005) TRIP6 is a RIP2-associated common signaling component of multiple NF-kB activation pathways. Journal of Cell Science 118 555-563 Li L, Braiteh FS and Kurzrock R (2005) Liposome-encapsulated curcumin. Cancer 104 1322-1331 Li L, Gao XL and Ding BX (2008) Inhibitory effect of sinomenine on H2O2-induced apoptosis in neonatal rat cardiomyocytes [Aritcle in Chinese]. Zhongguo Zhong Yao Za Zhi 33 939-941 Li L, Gondi CS, Dinh DH, Olivero WC, Gujrai M and Rao JS (2007) Transfection with anti-p65 intrabody suppresses invasion and angiogenesis in glioma cells by blocking nuclear factor-kB transcriptional activity. Clinical Cancer Research 13 2178-2190 Li L, Hailey DW, Soetandyo N, Li W, Lippincott-Schwartz J, Shu HB and Ye Y (2008) Localization of A20 to a lysosome-associated compartment and its role in NFkB signaling. Biochmica et Biophysica Acta inp ress Li L, Hamilton Jr RF and Holian A (1999) Effect of acrolein on human alveolar macrophage NF-kB activity. American Journal of Physiology 277 L550-L557 Li L and Frei B (2006) Iron chelation inhibits NF-kB-mediated adhesion molecule expression by inhibiting p22phox protein expression and NADPH oxidase activity. Arteriosclerosis, Thrombosis and Vascular Biology 26 2638-2643 Li L, Mamputa JC, Wiernsperger N and Renier G (2005) Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: inhibitory effect of metformin. Diabetes 54 2227-2234 Li L, Prabhakaran K, Zhang X, Zhang L, Liu H, Borowitz JL and Isom GE (2008) 1alpha,25-dihydroxyvitamin D(3) attenuates cyanide-induced neurotoxicity by inhibiting uncoupling protein-2 up-regulation. Journal of Neuroscience Research in press
Li L, Rao JN,
Bass BL and Wang JY (2001) NF-kB activation and susceptibility to apoptosis
after polyamine depletion in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 280 G992-G1004 Li L, Rossoni B, Sparatore A, Lee LC, Del Soldato P and Moore PK (2007) Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative. Free Radical Biology and Medicine 42 706-719 Li L, Sawamura T and Renier G (2003) Glucose enhances endothelial LOX-1 expression: role for LOX-1 in glucose-induced human monocyte adhesion to endothelium. Diabetes 52 1843-1850 Li L, Sawamura T and Renier G (2004) Glucose enhances human macrophage LOX-1 expression. Role for LOX-1 in glucose-induced macrophage foam cell formation. Circulation Research 94 892-901 Li L, Song GW, DU JB, Liu JR, Xu FS, Liu XY and Zhang T (2005) NEMODelta4-10 deletion of NEMO gene in Chinese incontinentia pigmenti cases [Article in Chinese]. Zhonghua Er Ke Za Zhi 43 89-92 Li L, Su J and Xie Q (2007) Differential reguation of key signaling moleculaes in innatue immunity and human diseases. Advances in Experimental Medicine and Biology 598 49-61 Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X and Harran PG (2004) A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 305 1471-1474 Li L, Wang XP and Wu K (2004) The therapeutic effect of oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine in mice with acute necrotizing pancreatitis [Article in Chinese]. Zhonghua Yi Xue Za Zhi 84 1235-1239 Li
L, Wang XP and Wu K (2007) The therapeutic effect of oxidized
1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine in rodents with
acute necrotizing pancreatitis and its mechanism. Li L and Wu LL (2004) Development and application of NF-kB decoy oligodeoxynucleiotide [Article in Chinese]. Sheng Li Ke Xue Jin Zhan 35 163-166 Li LB, Toan SV, Zelenaia O, Watson DJ, Wolfe JH, Rothstein JD and Robinson MB (2006) Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype. Journal of Neurochemistry in press Li LC, Shen
F, Hou Q and Cheng GF (2002) Inhibitory effect and mechanism of action of
sanggenon C on human polymorphonuclear leukocyte adhesion to human synovial
cells. Acta Pharmacol Sin 23 138-142 Li LF, Ouyang B, Choukroun G, Matyal R, Mascarenhas M, Jafari B, Bonventre JV, Force T and Quinn DA (2003) Stretch-induced IL-8 depends on c-Jun N-terminal and nuclear factor-kB-inducing kinases. American Journal of Physiology: Lung Cell and Molecular Physiology 285 L464-L475 Li LH, Wu LJ, Tashiro SI, Onodera S, Uchiumi F and Ikejima T (2006) The roles of Akt and MAPK family members in silymarin's protection against UV-induced A375-S2 cell apoptosis. International Immunopharmacology 6 190-197 Li LY, Zhao XL, Fei XF, Gu ZL, Qin ZH and Liang ZQ (2008) Bilobalide inhibits 6-OHDA-induced activation of NF-kB and loss of dopaminergic neurons in rat substantia nigra. Acta Pharmalogica Sinica 29 539-547
Li M, Cai JF
and Chiu JF (2002) Arsenic induces oxidative stress and activates stress gene
expressions in cultured lung epithelial cells. Journal of Cellular Biochemistry 87 29-38 Li M, Carpio
DF, Zheng Y, Bruzzo P, Singh V, Ouaaz F, Medzhitov RM and Beg AA (2001) An
essential role of the NF-kB/Toll-like receptor pathway in induction of
inflammatory and tissue-repair gene expression by necrotic cells. Journal of
Immunology 166 7128-7135 Li M, Chiou KR, Bugayenko A, Irani K and Kass DA (2005) Reduced wall compliance suppresses Akt-dependent apoptosis protection stimulated by pulse perfusion. Circulation Research 97 587-595 Li M, Cortez S, Nakamachi T, Batuman V and Arimura A (2006) Pituitary adenylate cyclase-activating polypeptide is a potent inhibitor of the growth of light chain-secreting human multiple myeloma cells. Cancer Research 66 8796-8803 Li M, Feng S, adn Wu M (2008) Multiple roles for nuclear localization signal (NLS, aa 442-472) of receptor interacting protein 3 (RIP3). Biochemical and Biophysical Research Communications in press Li M, Shillinglaw W, Henzel WJ and Beg AA (2001) The Rela(p65) subunit of NF-kB is essential for inhibiting double- stranded RNA-induced cytotoxicity. Journal of Biological Chemistry 276 1185-1194 Li M, Yang Q and Zhang Y (2007) Effects of CD134 monoclonal antibody on hemolysis activities and expression of perforin in peripheral blood mononuclear cells of systemic lupus erythematosus patients. Hybridoma (Larchmt) 26 191-200 Li M, Zhang X, Zheng X, Lian D, Zhang ZX, Ge W, Yang J, Vladau C, Suzuki M Chen D, Zhong R, Garcia B, Jevnikar AM and Min WP (2007) Immune modulation and tolerance induction by RelB-silenced dendritic cells through RNA interference. Journal of Immunology 178 5480-5487 Li MH, Jang JH, Sun B and Surh YJ (2004) Protective effects of oligomers of grape seed polyphenols against b-amyloid-induced oxidative cell death. Annals of the New York Academy of Sciences 1030 317-329 Li MJ, Li JJ, Zhao XB, Zhang MJ and Wang W (2005) Influence of mifepristone and lilopristone on proliferation and expression of nuclear factor-kB of ectopic stromal cells in vitro [Article in Chinese]. Zhonghua Fu Chan Ke Za Zhi 40 21-24 Li MY, Yip J, Hsin MK, Mok TS, Wu Y, Underwood MJ and Chen GG (2008) HO-1 plays a central role in NNK-mediated lung carcinogenesis. European Respiratory Journal in press Li N and
Karin M (1998) Ionizing radiation and short wavelength UV activate NF-kB
through two distinct pathways. Proceedings of the National Academy of Sciences
USA 95 13012-13017 Li N and
Karin M (1999) Is NF-kB the sensor of oxidative stress. FASEB Journal 13
1137-1143 Li N, Banin
S, Ouyang H, Li GC, Courtois G, Shiloh Y, Karin M and Rotman G (2000) ATM is
required for IkB kinase (IKKk) activation in response to DNA double strand breaks. Journal of Biological Chemistry 276 8898-8903 Li P, Mane SP, Sioson AA, Robinet CV, Heath LS, Bohnert HJ and Grene R (2006) Effects of chronic ozone exposure on gene expression in Arabidopsis thaliana ecotypes and in Thellungiella halophila. Plant Cell Environ 29 854-868 Li PC, Li SC, Lin YJ, Liang JT, Chien CT and Shaw CF (2005) Thoracic vagal efferent nerve stimulation evokes substance P-induced early airway bronchonstriction and late proinflammatory and oxidative injury in the rat respiratory tract. Journal of Biomedical Science 12 671-681 Li Q, Carr AL, Donald EJ, Skitzki JJ, Okuyama R, Stoolman LM and Chang AE (2005) Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type 1 pattern. Cancer Research 65 1063-1070 Li Q and Cherayil BJ (2003) Role of Toll-like receptor 4 in macrophage activation and tolerance during Salmonella enterica Serovar typhimurium infection. Infection and Immunity 71 4873-4882 Li Q, Ching AK, Chan BC, Chow SK, Lim PL, Ho TC, Ip WK, Wong CK, Lam CW, Lee KK, Chan JY and Chui YL (2004) A death receptor-associated antiapoptotic protein, BRE, inhibits mitochondrial apoptotic pathway. Journal of Biological Chemistry 279 52106-52116 Li Q and Engelhardt JF (2006) Interleukin-1beta induction of NFkB is partially regulated by H2O2-mediated activation of NFkB-inducing kinase. Journal of Biological Chemistry 281 1495-1505 Li Q, Estepa
G, Memet S, Israel A and Verma IM (2000) Complete lack of NF-kB activity in
IKK1 and IKK2 double-deficient mice:additional defect in neurulation. Genes
& Development 14 1729-1733 Li
Q, Guo Y, Tan W, Ou Q, Wu WJ, Sturza D, Dawn B, Hunt G, Cui C and Bolli R
(2007) Cardioprotection afforded by inducible nitric oxide synthase gene
therapy is mediated by cyclooxygenase-2 via a nuclear factor-kB dependent
pathway. Li Q, Harraz MM, Zhou W, Zhang LN, Ding W, Zhang Y, Eggleston T, Yeaman C, Banfi B and Engelhardt JF (2006) Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes. Molecular and Cellular Biology 26 140-154 Li Q, Kumar A, Gui JF and Yu FS (2007) Staphylococcus aureus lipoproteins trigger human corneal epithelial innate response through toll-like receptor-2. Microbial Pathogenesis in press Li Q, Laumonnier Y, Syrovets T and Simmet T (2007) Plasmin triggers cytokine induction in human monocyte-derived macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology in press Li Q, Lu Q, Bottero V, Estepa G, Morrison L, Mercurios F and Verma IM (2005) Enhanced NF-kB activation and cellular function in macrophages lacking IkB kinase 1 (IKK1). Proceedings of the National Academy of Sciences USA 102 12425-12430 Li Q, Lu Q,
Hwang JY, Buscher D, Lee KF, Izpisua-Belmonte JC and Verma IM (1999)
IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes
& Development 13 1322-1328 Li Q,
Vaingankar SM, Green HM and Martins-Green M (1999) Activation of the 9E3/cCAF
chemokine by phorbol esters occurs via multiple signal transduction pathways
that converge to MEK1/ERK2 and activate the Elk1 transcription factor. Journal
of Biological Chemistry 274 15454-15465 Li Q, Van Antwerp D, Mercurio F, Lee K-F and Verma IM (1999) Severe liver degeneration in mice lacking the IkB kinase 2 gene. Science 284 321-325 Li Q and
Verma
IM (2002) NF-kB regulation in the immune system. Nature Reviews Immunology 2
725-734 Li Q, Withoff S and Verma IM (2005) Inflammation-associated cancer: NF-kB is the lynchpin. Trends in Immunology 26 318-325 Li Q, Yu YY, Zhu ZG, Ji YB, Zhang Y, Liu BY, Chen XH and Lin YZ (2005) Effect of NF-kB constitutive activation on proliferation and apoptosis of gastric cancer cell lines. European Surgical Research 37 105-110 Li Q, Zhang Y, Marden JJ< Banfi B adn Engelhardt JF (2008) Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury. Biochemical Journal 411 531-541 Li
QQ, Burt
DR and Bever CT (2001) Glatiramer acetate inhibition of tumor necrosis
factor-alpha-induced RANTES expression and release from U-251 MG human
astrocytic cells. Journal of Neurochemistry 77 1208-1217 Li R, Yang L, Lindholm K, Konishi Y, Yue X, Hampel H, Zhang D and Shen Y (2004) Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death. Journal of Neuroscience 24 1760-1771 Li RW, Man RY, Vanoutte PM and Leung GP (2008) Stimulation of ecto-5'nucleotidase in human umbilical vein endothelial cells by lipopolysaccharide. American Journal of Physiology: Heart and Circulatory Physiology in press Li S and Bobek LA (2006) Functional analysis of human MUC7 mucin gene 5'-flanking region in lung epithelial cells. American Journal of Respiratory Cell and Molecular Biology 35 593-601 Li
S, E M and Yu B (2007) Adriamycin induces myocardium apoptosis through
activation of nuclear factor kB in rat. Li S, Gokden N, Okusa MD, Bhatt R and Portilla D (2005) Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF. American Journal of Physiology: Renal Physiology 289 F469-F480 Li S, Ni Z, Cong B, Gao W, Xu S, Wang C, Yao Y, Ma C adn Ling Y (2007) CCK8 inhibits LPS-induced IL-1b production in pulmonary interstitial macrophages by modulating PKA, p38 and NF-kB pathway. Shock 27 678-686 Li S and
Sedivy JM (1993) Raf-1 protein kinase activates the NF-kB transcription factor
by dissociating the cytoplasmic NF-kB-IkB complex. Proceedings of the National
Academy of Sciences USA 90 9247-9251 Li S and Shang Y (2007) Regulation of SRC family coactivators by post-translational modifications. Cellular Signaling in press Li S and Stark G (2002) NFkB-dependent signaling pathways. Experimental Hematology 30 285-296 Li S, Wang L, Berman MA, Zhang Y and Dorf ME (2006) RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kB signaling. Molecular Cell 24 497-509 Li S, Wang X, Qiu J, Si Q, Wang H, Guo H, Sun R and Wu Q (2005) Angiotensin II stimulates endothelial integrin beta(3) expression via nuclear factor-kB activation. Experimental Aging Research 32 47-60
Li S, Yan T,
Yang JQ, Oberley TD, Oberley LW (2000) The role of cellular glutathione
peroxidase redox regulation in the suppression of tumor cell growth by
manganese superoxide dismutase. Cancer Research 60 3927-3939
Li S, Zhang Y and Zhao J (2007) Preparation and suppressive effect of
astragalus polysaccharide in glomerulonephritis rats. Li SF, Fujita F, Hirai M, Lu R, Niida H and Nakanishi M (2003) Genomic structure and characterization of the promoter region of the human NAK gene. Gene 307 57-64 Li SL, Reddy MA, Cai Q, Meng L, Yuan H, Lanting L and Natarajan R (2006) Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice. Diabetes 55 2611-2619
Li SM, Wang XM, Qiu J, Si Q, Guo HY, Sun RY and Wu QX (2005) Inhibitory
effects of alpha-zearalenol on angiotensin II-induced integrin beta3 mRNA via
suppression of nuclear factor-kappaB. Li T, Hu J and Li L (2004) Characterization of Tollip protein upon lipopolysaccharide challenge. Molecular Immunology 41 85-92
Li T, Narhi
LO, Wen J, Philo JS, Sitney K, Inoue J, Yamamoto T and Arakawa T (1998)
Interactions between NFkB and its inhibitor IkB: biophysical characterization
of a NFkB/IkB-a complex. Journal of Protein Chemistry 17 757-763 Li T, Narhi
LO, Wen J, Philo JS, Sitney K, Inoue J, Yamamoto T and Arakawa T (1998)
Interactions between NFkB and its inhibitor IkB: biophysical
characterization of a NFkB/IkB-a complex. Journal of Protein Chemistry 17
757-763 Li T, Southall MD, Yi Q, Pei Y, Lewis D, Al-Hassani M, Spandau D and Travers JB (2003) The epidermal platelet-activating factor receptor augments chemotherapy-induced apoptosis in human carcinoma cell lines. Journal of Biological Chemistry 278 16614-16621 Li TJ, Jia LP, Gao XL and Huang AL (2006) Gene therapy that inhibits NF-kB results in apoptosis of human hepatocarcinoma by recombinant adenovirus. World Journal of Gastroenterology 12 5287-5292 Li TL, Li Y, Zhang GH, Sun YN and Li YQ (2004) Expression and DNA binding activity of NF-kB in mucosal tissue of chronic rhinosinusitis [Article in Chinese]. Zhonghua Er Bi Yan Hou Ke Za Zhi 39 489-492 Li W, Bengtson MH, Ulbrich A, Matsuda A, Reddy VA, Orth A, Chanda SK, Batalov S and Joazeiro CA (2008) Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS 3 e1487 Li W, He H, Kawakita T, Espana EM and Tseng SC (2005) Amniotic membrane induces apoptosis of interferon-gamma activated macrophages in vitro. Experimental Eye Research 82 282-292 Li W, Maeda N and Beck MA (2006) Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice. Journal of Nutrition 136 2611-2616 Li W, Wang T, Ma C, Xiong T, Zhu Y and Wang X (2006) Calcitonin gene-related peptide inhibits interleukin-1beta-induced endogenous monocyte chemoattractant protein-1 secretion in type II alveolar epithelial cells. American Journal of Physiology: Cellular Physiology 291 C4456-C465 Li W, Wang YL, Kang LH and Wang GJ (2005) Up-regulation of costimulatory molecules by sodium butyrate in acute leukemia cells and its molecular mechanism [Article in Chinese]. Zhonghua Xue Ye Xue Za Zhi 26 265-268 Li W, Zheng
T, Wang J, Altura BT and Altura BM (1999) Pyrrolidine dithiocarbamate prevents
ethanol-induced elevation of [Ca2+]i in cultured canine cerebral vascular
smooth muscle cells. Neuroscience Letters 266 205-208 Li WD, Dong YJ, Tu YY and Lin ZB (2006) Dihydroarteannuin ameliorates lupus symptom of BXSB mice by inhibiting production of TNF-a and blocking the signaling pathway NF-kB translocation. International Immunopharmacology 6 1243-1250 Li WG, Gavrila D, Liu X, Wang L, Gunnlaugsson S, Stoll LL, McCormick ML, Sigmund CD, Tang C and Weintraub NL (2004) Ghrelin inhibits proinflammatory responses and nuclear factor-kB activation in human endothelial cells. Circulation 109 2221-2226 Li WM, Liu W, Gao C, Zhou BG, Yang SS, Wang Z, Zhang RH, Gan RT, Kong YH and Li Y (2006) Antigen-specific tolerance induced by IL-10 gene modified immature dendritic cells in experimental autoimmune myocarditis in rats. Chinese Medical Journal (English) 119 1646-1652 Li X (2008) IRAK4 in TLR/IL-1R signaling: possible clinical applications. European Journal of Immunology 38 614-618 Li X, Bradford BU, Dalldorf F, Goyert SM, Stimpson SA, Thurman RG and Makarov SS (2004) CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan-polysaccharide complexes of Gram-positive bacterial cell walls. Arthritis Research Therapy 6 R273-R281 Li X,
Bradford BU, Wheeler MD, Stimpson SA, Pink HM, Brodie TA, Schwab JH and
Thurman RG (2001) Dietary glycine prevents peptidoglycan
polysaccharide-induced reactive arthritis in the rat: role for glycine-gated
chloride channel. Infection and Immunity 69 5883-5891 Li X, Chen D, Yin S, Meng Y, Yang H, Landis-piwowar KR, Li Y, Sarkar FH, Reddy GP, Dou QP and SHeng S (20007) Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cells. Journal of Cellular Physiolgoy in press Li X, Commane
M, Jiang Z and Stark GR (2001) IL-1-induced NFkB and c-Jun N-terminal kinase
(JNK) activation diverge at IL-1 receptor-associated kinase (IRAK).
Proceedings of the National Academy of Sciences USA 98 4461-4465 Li X, Commane
M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M and Stark GR (2000) Act1,
an NF-kB-activating protein. Proceedings of the National Academy of Sciences
USA 97 10489-10493 Li X, Du JR, Wang WD, ZHeng XY, Sun W, Zong X, Sheng H and Qian ZM (2006) Experimental study of effect of tanshinone on artery restenosis in rat carotid injury model [Article in Chinese]. Zhongguo Zhong Yao Za Zhi 31 580-584 Li X, Fang Y,
Zhao X, Jiang X, Duong T and Kain SR (1999) Characterization of NFkB
activation by detection of green fluorescent protein-tagged IkappaB
degradation in living cells. Journal of Biological Chemistry 274 21244-21250 Li X, Hua L, Deng F, Bai X, Zeng W, Lu D, Su Y and Luo S (2005) NF-kB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells. Life Sciences 77 2794-2803 Li X, Kiumura H, Hirota K, Kasuno K, Torii K, Okada T, Kurooka H, Yokota Y and Yoshida H (2005) Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells. Kidney International 68 569-583 Li X, Lei T, Xia T, Chen X, Feng S, Chen H, Chen Z, Peng Y and Yang Z (2008) Molecular characterization, chromosomal and expression patterns of three aquaglyceroporins (AQP3, 7, 9) from pig. Comparative Biochemistry and Physiology B Biochemistry and Molecular Biology in press Li X and
Liao
WS-L (1991) Expression of rat serum amyloid A1 gene involves both C/EBP-like
and NF-kB-like transcription factors. Journal of Biological Chemistry 266
15192-15201 Li X and Liao
WSL (1992) Cooperative effects of C/EBP-like and NFkB-like binding sites on
rat serum amyloid A1 gene expression in liver cells. Nucleic Acids Research 20
4765-4772 Li X and Makarov SS (2006) An essential role of NF-kB in the "tumor-like" phenotype of arthritic synoviocytes. Proceedings of the Natlional Academy of Sciences USA in press Li X, Massa
PE, Hanidu A, Peet GW, Aro P, Savitt A, Mische S, Li J and Marcu KB (2002)
IKKa, IKKb and NEMO/IKKg are each required for the NF-kB mediated inflammatory
response program. Journal of Biological Chemistry 277 45129-45140 Li X, Meng Y, Chen Q, Yang XS, Zhou GS and Wu PS (2005) Effect of Angiotensin II on NF-kB activity and expression of PDGF-BB, TGF beta 1 and COX-2 in Kupffer's cells [Article in Chinese]. Zhonghua Gan Zang Bing Za Zhi 13 150-151 Li X, Meng Y, Jiang B, Yang XS, Wang WW, Guo D, Lai ZS and Zhang ZS (2005) Effects of angiotensin II and aldosterone on NF-kB binding activity in hepatic stellate cells [Article in Chinese]. Zhonghua Yi Xue Za Zhi 374-380 Li X, Meng Y, Wu P, Zhang Z and Yang X (2006) Angiotensin II and Aldosterone stimulating NF-kB and AP-1 activation in hepatic fibrosis of rat. Regulatory Peptides in press Li X, Meng Y, Yang XS, Mi LF and Cai SX (2005) ACEI attenuates the progression of CCl(4)-induced rat hepatic fibrogenesis by inhibiting TGF-beta1, PDGF-BB, NF-kB and MMP-2,9. World Journal of Gastroenterology 11 4807-4811 Li X and Minden A (2005) Pak4 functions in TNFa induced survival pathways by facilitating TRADD binding to the TNF receptor. Journal of Biological Chemistry 280 41192-41200 Li X, Tupper JC, Bannerman DD, Winn RK, Rhodes CJ and Harlan JM (2003) Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kB in endothelial cells. Infection & Immunity 71 4414-4420 Li X, Wang H, Touma E, Qi Y, Rousseau E, Quigg RJ and Ryaby JT (2007) TP508 accelerates fracture repair by promoting cell growth over cell death. Biochemical and Biophysical Research Communications in press Li X, Wen Z, He X and He S (2006) Effects of cinnamic acid on expression of tissue factor induced by TNFa in endothelial cells and its mechanisms. Journal of Chinese Medical Association 69 207-212 Li X, Yang Y
and Ashwell JD (2002) TNF-RII and c-IAP1 mediate ubiquitination and
degradation of TRAF2. Nature 416 345-347 Li X, Xing D, Wang J, Zhu DB, Zhang L, Chen XJ, Sun Fy and Hong A (2006) Effects of IkBa and its mutants on NF-kB and p53 signaling pathways. World Journal of Gastroenterology 12 6658-6664 Li X, Zhang R, Luo D, Park SJ, Wang Q, Kim Y and Min W (2005) TNF-induced desumoylation and cytoplasmic translocation of HIPK1 are critical for ASK1-JNK/p38 activation. Journal of Biological Chemistry 280 15061-15070 Li XC, Ma YF and Wang XH (2006) Role of NF-kB as effector of IPC in donor livers before liver transplantation in rats. Transplantation Proceedings 38 1584-1587 Li XC and Zhuo JL (2008) Nuclear factor-kB as a hormonal intracellular signaling molecule: focus on angiotensin II-induced cardiovascular and renal injury. Current Opinion in Nephrology and Hypertension in press Li XD, Sun L, Seth RB, Pineda G and Chen ZJ (2005) Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proceedings of the National Academy of Sciences USA 102 17717-17722 Li XH and
Gaynor RB (1999) Regulation of NF-kB by the HTLV-1 Tax protein. Gene
Expression 7 233-245 Li XH, Murphy
KM, Palka KT, Surabhi RM and Gaynor RB (1999) The human T-cell leukemia virus
type-1 Tax protein regulates the activity of the IkappaB kinase complex.
Journal of Biological Chemistry 274 34417-34424 Liu XM, Jia Z, Zhou ZQ and Xu JG (2007) Cardioprotection of recombinant human erythropoietin pretreatment on ischemia-reperfused hearts and mechanism thereof: experiment with rats [Article in Chinese]. Zhonghua Yi Xue Za Zhi 87 2463-2467 Li XZ, Zhou Y, Liu CF and Bai LM (2007) A dual effect on the growth of astrocytes of lipopolysaccharide [Article in Chinese]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 23 934-936 Li Y, Ahmed F, ALi S, Philip PA, Kucuk O and Sarkar FH (2005) Inactivation of nuclear factor kB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. Cancer Research 65 6934-6942 Li Y, Chinni SR and Sarkar FH (2005) Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kB pathways in prostate cancer cells. Frontiers in Bioscience 10 236-243 |