|
References Relevant
publications listed by the last name of the first author.
Ha EM, Oh CT, Ryu JH, Bae YS, Kang SW, Jang IH, Brey PT and Lee WJ
(2005) An antioxidant system required for host protection against gut
infection in Drosophila. Developmental Cell 8 125-132
Ha H, Lee JH, Kim HN, Kwak HB, Kim HM, Lee SE, Rhee JH, Kim HH and Lee ZH (2008) Stimulation by TLR5 modulates osteoclast differentiation through STAT1/IFN-b. Journal of Immunology 180 1382-1389 Ha H, Park J, Kim YS and Endou H (2004) Oxidative stress and chronic allograft nephropathy. Yonsei Medical Journal 45 1049-1052
Ha HC (2004) Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia. Proceedings of the National Academy of Sciences USA 101 5087-5092 Ha HH, Kim JS and Kim BM (2007) Novel heterocycle-substituted pyrimidines as inhibitors of NF-kB transcription regulation related to TNF-a cytokine release. Bioorganic Medicinal Chemistry Letters in press Ha HH, Park SY, Ko WS and Kim Y (2008) Gleditsia sinensis thorns inhibit the production of NO through NF-kB suppression in LPS-stimulated macrophages. Journal of Ethnopharmacology in press Ha T, Li Y, Gao X, McMullen JR, Shioi T, Izumo S, Kelley JL, Zhao A, Haddad GE, WIlliams DL, Browder IW, Kao RL and Li C (2005) Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkB activation in vivo. Free Radical Biology and Medicine 39 1570-1580 Ha WY, Li XJ, Yue PY, Wong DY, Yue KK, Chung WS, Zhao L, Leung PY, Liu L and Wong RN (2006) Gene expression profiling of human synovial sarcoma cell line (Hs701.T) in response to IL-1beta stimulation. Inflammationa Research 55 293-299 Haaning Andersen AD, Lange M and Lillevang ST (2003) Allelic variation of the inducible costimulator (ICOS) gene: detection of polymorphisms, analysis of the promoter region, and extended haplotype estimation. Tissue Antigens 61 276-285
Haas E, Grell
M, Wajant H and Scheurich P (1999) Continuous autotropic signaling by
membrane-expressed tumor necrosis
factor. Journal of Biological Chemistry 274
18107-18112 Haase MG, Klawitter A and Baretton GB (2004) IkBg is expressed in mast cells. Virchows Arch 445 515-520 Haase MG, Klawitter A, Geyer P, Alheit H, Baumann M, Kriegel TM, Kasper M and Baretton GB (2003) Sustained elevation of NF-kB DNA binding activity in radiation-induced lung damage in rats. International Journal of Radioation Biology 79 863-877 Haase R, Kirschning CJ, Sing A, Schrottner P, Fukase K, Kusumoto S, Wagner H, Heesemann J and Ruckdeschel K (2003) A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages. Journal of Immunology 171 4294-4303 Haase R, Richter K, Pfaffinger G, Courtois G and Ruckdeschel K (2005) Yersinia outer protein P suppresses TGF-beta-activated kinase-1 activity to impair innate immune signaling in Yersinia enterocolitica-infected cells. Journal of Immunology 175 8209-8217 Habara K, Hamada Y, Yamada M, Tokuhara K, Tanaka H, Kaibori M, Kamiyama Y, Nishizawa M, Ito S and Okumura T (2007) Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. Nitric Oxide in press Habelhah H,
Frew IJ, Laine A, Janes PW, Relaix F, Sassoon D, Bowtell DD and Ronai Z (2002)
Stress-induced decrease in TRAF2 stability is mediated by Siah2. EMBO Journal
21 5756-5765 Habelhah H, Takahashi S, Cho SG, Kadoya T, Watanabe T and Ronai Z (2004) Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kB. EMBO Journal 23 322-332 Habvens F, Lapham AS, Dallman CL, Pickering BM, Michels J, Marcusson EG, Johnson PW and Packham G (2006) Distinct promoters mediate constitutive and inducible Bcl-X(L) expression in malignant lymphocytes. Oncogene in press Habens F, Srinivasan N, Oakley F, Mann DA, Ganesan A and Packham G (2005) Novel sulfasalazine analogues with enhanced NF-kB inhibitory and apoptosis promoting activity. Apoptosis 10 481-491 Haberstroh U, Pocock J, Gomez-Guerrero C, Helmchen U, Hamann A, Gutierrez-Ramos JC, Stahl RA and Thaiss F (2002) Expression of the chemokines MCP-1/CCL2 and RANTES/CCL5 is differentially regulated by infiltrating inflammatory cells. Kidney International 62 1264-1276 Habib A, Shamseddeen I, Nasrallah MS, Antoun TA, Nemer G, Bertoglio J, Badreddine R and Badr KF (2007) Modulation of COX-2 expression by statins in human monocytic cells. FASEB Journal in press Habib AA, Chatterjee S, Park SK, Ratan RR, Lefebvre
S and Vartanian T (2001) The epidermal growth factor receptor engages receptor
interacting protein and nuclear factor-kB (NF-kB)-inducing kinase to activate
NF-kB. Identification of a novel receptor-tyrosine kinase signalosome. Journal
of Biological Chemistry 276 8865-8874 Habraken Y, Jolois O and Piette J (2003) Differential involvement of the hMRE11/hRAD50/NBS1 complex, BRCA1 and MLH1 in NF-kB activation by camptothecin and X-ray. Oncogene 22 6090-6099 Habraken Y and Piette J (2006) NF-kB activation by double-strand breaks. Biochemical Pharmacology in press
Habraken Y,
Piret B and Piette J (2001) S phase dependence and involvement of NF-kB
activating kinase to NF-kB activation by camptothecin. Biochemical Pharmacology 62
603-616 Hachiya M, Takada M, Sekikawa K and Akashi M (2004) Endogenous production of TNFalpha is a potent trigger of NFkB activation by irradiation in human monocytic cells THP-1. Cytokine 25 147-154
Hacker H
(2000) Signal transduction pathways activated by CpG-DNA. Current Topics in Microbiology
and Immunology 247 77-92 Hacker H and Karin M (2002) Is NF-kB2/p100 a direct activator of programmed cell death? Cancer Cell 2 431-433 Hacker H and Karin M (2006) Regulation and function of IKK and IKK-related kinases. Science STKE (357) re13
Hackstein H,
Morelli AE, Larregina AT, Ganster RW, Papworth GD, Logar AJ, Watkins SC, Falo
LD and Thomson AW (2001) Aspirin inhibits in vitro maturation and in vivo
immunostimulatory function of murine myeloid dendritic cells. Journal of
Immunology 166 7053-7062 Haddad J
(2002) Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive
transcription factors. Cell Signal 14 879 Haddad J
(2002) Redox regulation of pro-inflammatory cytokines and IkB-a/NF-kB nuclear
translocation and activation. Biochemical and Biophysical Research
Communications 296 847 Haddad JJ
(2000) Glutathione depletion is associated with augmenting a proinflammatory
signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines
in the alveolar epithelium. Cytokines Cell Mol Ther 6 177-187 Haddad JJ
(2001) L-Buthionine-(S,R)-sulfoximine, an irreversible inhibitor of
gamma-glutamylcysteine synthetase, augments LPS-mediated pro-inflammatory
cytokine biosynthesis: evidence for the implication of an IkB-a/NF-kB
insensitive pathway. European Cytokine Network 12 614-624 Haddad JJ
(2001) Oxygen-sensitive pro-inflammatory cytokines, apoptosis signaling and
redox-responsive transcription factors in development and pathophysiology.
Cytokines Cell Mol Ther 7 1-14 Haddad JJ
(2002) Nuclear factor (NF) -kB blockade attenuates but does not abrogate
LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial
cells. Biochemical and Biophysical Research Communications 293 252-257 Haddad JJ
(2002) Oxygen homeostasis, thiol equilibrium and redox regulation of
signalling transcription factors in the alveolar epithelium. Cell Signal 14
799-810 Haddad JJ
(2002) Recombinant TNF-a mediated regulation of the IkB-a/NF-kB signaling
pathway: evidence for the enhancement of pro- and anti-inflammatory cytokines
in alveolar epithelial cells. Cytokine 17 301-310 Haddad JJ
(2002) The involvement of L-gamma-glutamyl-L-cysteinyl-glycine (glutathione/GSH)
in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation
of pro-inflammatory cytokine production. Biochemical Pharmacology 63 305-320 Haddad JJ (2002) Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for nuclear factor-kB. Critical Care 6 481-490 Haddad JJ (2002) Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology. Respiration Research 3 26 Haddad JJ (2003) Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alpha. Critical Care 7 47-54 Haddad JJ (2004) Oxygen sensing and oxidant/redox-related pathways. Biochemical and Biophysical Research Communications 316 969-977 Haddad JJ (2004) On the antioxidant mechanisms of Bcl-2: a retrospective of NF-kB signaling and oxidative stress. Biochemical and Biophysical Research Communications 322 355-363 Haddad JJ (2005) Amiloride and the regulation of NF-kB: an unsung crosstalk and missing link between fluid dynamics and oxidative stress-related inflammation-controversy or pseudo-controversy? Biochemical and Biophysical Research Communications 327 373-381 Haddad JJ and
Fahlman CS (2002) Nuclear factor-kB-independent regulation of
lipopolysaccharide-mediated interleukin-6 biosynthesis. Biochemical and
Biophysical Research Communications 291 1045-1051 Haddad JJ and Harb HL (2005) Cytokines and the regulation of hypoxia-inducible factor (HIF)-1a. International Immunopharmacology 5 461-483 Haddad JJ and
Land SC (2000) O(2)-evoked regulation of HIF-1alpha and NF-kB in perinatal
lung epithelium requires glutathione biosynthesis. Am J Physiol Lung Cell Mol
Physiol 278 L492-L503 Haddad JJ and
Land SC (2001) Nuclear factor-kB blockade attenuates but does not abrogate
lipopolysaccharide-dependent tumor necrosis factor-alpha biosynthesis in
alveolar epithelial cells. Biochemical and Biophysical Research Communications
285 267-272 Haddad JJ and
Land SC (2002) Amiloride blockades lipopolysaccharide-induced proinflammatory
cytokine biosynthesis in an IkB-a/NF-kB-dependent mechanism. Evidence for the
amplification of an antiinflammatory pathway in the alveolar epithelium. Am J
Respir Cell Mol Biol 26 114-126 Haddad JJ and
Land SC (2002) Redox signaling-mediated regulation of
lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar
epithelial cells. Antioxid Redox Signal 4 179-193 Haddad JJ and
Land SC (2002) Redox/ROS regulation of lipopolysaccharide-induced
mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-a
biosynthesis. British Journal of Pharmacology 135 520-536 Haddad JJ,
Collett A, Land SC, Olver RE and Wilson SM (2001) NF-kB blockade reduces the
O2-evoked rise in Na+ conductance in fetal alveolar cells. Biochemical and
Biophysysical Research Communications 281 987-992 Haddad JJ and Harb HL (2005) l-gamma-Glutamyl-l-cysteinyl-glycine (glutathione; GSH) and GSH-related enzymes in the regulation of pro- and anti-inflammatory cytokines: a signaling transcriptional scenario for redox(y) immunologic sensor(s)? Molecular Immunology 42 987-1014 Haddad JJ,
Land SC, Tarnow-Mordi WO, Zembala M, Kowalczyk D and Lauterbach R (2002)
Immunopharmacological potential of selective phosphodiesterase inhibition. II.
Evidence for the involvement of an inhibitory-kB/nuclear factor-kB-sensitive
pathway in alveolar epithelial cells. J Pharmacol Exp Ther 300 567-576 Haddad JJ,
Lauterbach R, Saade NE, Safieh-Garabedian B and Land SC (2001) Alpha-melanocyte-related
tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kB
translocation and activation: evidence for involvement of an
interleukin-1b193-195 receptor antagonism in the alveolar epithelium.
Biochemical Journal 355 29-38 Haddad JJ,
Saade NE and Safieh-Garabedian B (2002) Redox regulation of TNF-alpha
biosynthesis: augmentation by irreversible inhibition of
gamma-glutamylcysteine synthetase and the involvement of an
IkB-a/NF-kB-independent pathway in alveolar epithelial cells. Cell Signal 14
211-218 Haddad JJ,
Safieh-Garabedian B, Saade NE and Land SC (2001) Thiol regulation of
pro-inflammatory cytokines reveals a novel immunopharmacological potential of
glutathione in the alveolar epithelium. J Pharmacol Exp Ther 296 996-1005 Haddad JJ, Safieh-Garabedian B, Saade NE and Lauterbach R (2002) Inhibition of glutathione-related enzymes augments LPS-mediated cytokine biosynthesis: involvement of an IkB/NF-kB-sensitive pathway in the alveolar epithelium. International Immunopharmacology 2 1567-1583 Hadjidakis
DJ and Androulakis II (2006) Bone remodeling. Hadjigogos K (2003) The role of free radicals in the pathogenesis of rheumatoid arthritis. Panminerva Med 45 7-13 Haeberle HA, Casola A, Gatalica Z, Petronella S, Dieterich HJ, Ernst PB, Brasier AR and Garofalo RP (2004) IkB kinase is a critical regulator of chemokine expression and lung inflammation in respiratory syncytial virus infection. Journal of Virology 78 2232-2241 Haeberle HA,
Takizawa R, Casola A, Brasier AR, Dieterich HJ, Van Rooijen N, Gatalica Z and
Garofalo RP (2002) Respiratory syncytial virus-induced activation of nuclear
factor-kB in the lung involves alveolar macrophages and Toll-like receptor
4-dependent pathways. Journal of Infectious Disease 186 1199-1206 Haefner B
(2002) NF-kB: arresting a major culprit in cancer. Drug Discovery Today 7
653-663 Haefner
B (2003) A model for NF-kB regulation by GSK-3beta. Drug Discovery Today
8 1062-1063 Haefner B (2005) The transcription factor NF-kB as drug target. Progress in Medicinal Chemistry 43 137-188 Haefner B (2006) Targeting NF-kB in anticancer adjunctive chemotherapy. Cancer Treatment and Research 130 219-245 Haegens A, Barret TF, Gell J, Shukla A, Macpherson M, Vacek P, Poynter ME, Butnor KJ, Janssen-Heininger YM, Steele C and Mossman BT (2007) Airway epithelial NF-kB activation modulates asbestos-induced inflammation and mucin production in vivo. Journal of Immunology 178 1800-1808 Haehnel V,
Schwarzfischer L, Fenton MJ and Rehli M (2002) Transcriptional regulation of
the human toll-like receptor 2 gene in monocytes and macrophages. Journal of
Immunology 168 5629-5637 Hafeez BB, Ahmed S, Wang N, Gupta S, Zhang A and Haqqi TM (2006) Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kB. Toxicology and Applied Pharmacology 216 11-19 Hafez M, Al-Tonbery Y, El-Bayoumi MA, Hatem N, Hawas S, Mansour A, Marzouk I,Hafez MM, Yahia S and Farahat N (2007) Markers of apoptosis and proliferation related gene products as predictors of treatment outcome in childhood acute lymphoblastic leukemia. Hematology 12 209-218 Hafner A, Brandenburg B and Hildt E (2003) Reconstitution of gene expression from a regulatory-protein-deficient hepatitis B virus genome by cell-permeable HBx protein. EMBO Reports 4 767-773 Haffner MC, Berlato C and Doppler W (2006) Exploiting our knowledge of NF-kB signaling for the treatment of mammary cancer. Journal of Mammary Gland Biology and Neoplasia in press Haga JH, Kaunas R, Radeff-Huang J, Weems JM, Estrada KD, Chien S, Brown JH and Seasholtz TM (2008) Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kB activation. Biochemical and Biophysical Research Communications in press Hagar HH, El Medany A, El Eter E and Arafa M (2006) Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats. European Journal of Pharmacology in press Hagemann T, Lawrence T, McNeish I, Charles KQ, Kulbe H, Thompson RG, Robinson SC, Balkwill FR (2008) "Re-educating" tumor-associated macrophages by targeting NF-kB. Journal of Experimental Medicine in press Hagemann T, Wilson J, Kulbe H, Li NF, Leinster DA, Charles K, Klemm F, Pukrop T, Binder C and Balkwill FR (2005) Macrophages induce invasiveness of epithelial cancer cells Via NF-kB and JNK. Journal of Immunology 175 1197-1205 Hagerkvist R, Sandler S, Mokhtari D and Welsh N (2006) Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kB activation and anti-apoptotic preconditioning. FASEB Journal in press Hagi-Pavli E, Farthing P, Henshaw F and Kapas S (2005) Presentation of ICAM-1 protein at the cell surface of oral keratinocytes in the presence of adrenomedullin and corticotrophin. Cellular Physiology and Biochemistry 15 167-174 Hagihara K, Nishikawa T, Sugamata Y, Song J, Isobe T, Taga T and Yoshizaki K (2005) Essential role of STAT3 in cytokine-driven NF-kB-mediated serum amyloid A gene expression. Genes Cells 10 1051-1063 Hagimoto N,
Kuwano K, Kawasaki M, Yoshimi M, Kaneko Y, Kunitake R, Maeyama T, Tanaka T and
Hara N (1999) Induction of interleukin-8 secretion and apoptosis in
bronchiolar epithelial cells by Fas ligation. American Journal of Respiratory Cell
and Molecular Biology 21
436-445 Hagiwara S, Iwasaka H, Hasegawa A, Asai N and Noguchi T (2008) High-dose intravenous immunoglobulin G improves systemic inflammation in a rat model of CLP-induced sepsis. Intensive Care Medicine in press Hagiwara S, Iwasaka H, Hasegawa A, Koga H and Noguchi T (2008) Effects of hyperglycemia and insulin therapy on HMGB1 in endotoxin-induced acute lung injury in a rat model. Critical Care Medicine in press Hagiwara S, Iwasaka H, Hidaka S, Hishiyama S and Noguchi T (2008) Danaparoid sodium inhibits systemic inflammation and prevents endotoxin-induced acute lung injury in rats. Critical Care 12 R43 Hagiwara S, Iwasaka H, Matumoto S and Noguchi T (2007) Nafamostat mesilate inhibits high-mobility group box 1 by lipopolysaccharide stimulation in murine macrophage RAW 264.7. Shock 27 429-435 Hagiwara S, Iwasaka H, Matsumoto S and Noguchi T (2007) High dose antithrombin III inhibits HMGB1 and improves endotoxin-induced acute lung injury in rats. Intensive Care Medicine in press Hagiwara S, Iwasaka H, Togo K and Noguchi T (2008) A neutrophil elastase inhibitor, sivelestat, reduces lung injury following endotoxin-induced shock in rats by inhibiting HMGB1. Inflammation in press Hagood JS,
Mangalwadi A, Guo B, MacEwen MW, Salazar L and Fuller GM (2002) Concordant and
discordant interleukin-1-mediated signaling in lung fibroblast thy-1
subpopulations. Am J Respir Cell Mol Biol 26 702-708 Hah N and Lee ST (2003) An absolute role of the PKC-dependent NF-kB activation for induction of MMP-9 in hepatocellular carcinoma cells. Biochemical and Biophysical Research Communications 305 428-433 Hahm KB, Kim DH, Lee KM, Lee JS, Surh YJ, Kim YB, Yoo BM, Kim JH, Joo HJ, Cho YK, Nam KT and Cho SW (2003) Effect of long-term administration of rebamipide on Helicobacter pylori infection in mice. Aliment Pharmacol Ther 18 24-38 Hahm KB, Song YJ, Oh TY, Lee JS, Surh YJ, Kim YB, Yoo BM, Kim JH, Han SU, Nahm KT, Kim MW, Kim DY and Cho SW (2003) Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible? J Biochem Mol Biol 36 82-94
Hahn P,
Novikova E, Scherback L, Janik C, Pavlish O, Arkhipov V, Nicholls J, Muller-Lantzsch
N, Gurtsevitch V and Grasser FA (2001) The LMP1 gene isolated from Russian
nasopharyngeal carcinoma has no 30-bp deletion. International Journal of
Cancer 91 815-821 Hahn WC,
Weinberg RA (2002) Modelling the molecular circuitry of cancer. Nature 2
331-341 Hai T, Yeung ML, Wood TG, Wei Y, Yamaoka S, Gatalica Z, Jeang KT and Brasier AR (2006) An alternative splice product of IkB kinase (IKK{g}), IKKg-d, differentially mediates cytokine and human T-cell leukemia virus type 1 Tax-induced NF-kB activation. Journal of Virology 80 4227-4241 Hai Z, Jiang C, Zhang J, Wang L and Fang K (2006) Relationship between carbachol hyperstimulation-induced pancreatic acinar cellular injury and trypsinogen or NF-kB activation in rats in vitro. J Huazhong Univ Sci Technolog Med Sci 26 34-5, 58 Haider DG, Leuchten N, Schaller G, Gouya G, Kolodjaschna J, Schmetterer L, Kapiotis S and Wolzt M (2006) C-reactive protein is expressed and secreted by peripheral blood mononuclear cells. Clinical and Experimental Immunology 146 533-539 Hailemariam TK, Huan C, Liu J, Li Z, Roman C, Kalbfeisch M, Bui HH, Peake DA, Kuo MS, Cao G, Wadgaonkar R and Jiang SC (2008) Sphingomyelin synthase 2 deficiency attenuate NFkB activation. Artheriosclerosis, Thrombosis and Vaascular Biology in press Hailer-Morrison MK, Kotler JM, Martin BD and Sugden KD (2003) Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-2'-deoxyguanosine lesions in the NF-kB promoter element. Biochemistry 42 9761-9770 Hajishengallis G and Genco RJ (2004) Downregulation of the DNA-binding activity of nuclear factor-kB p65 subunit in Porphyromonas gingivalis Fimbria-induced tolerance. Infection & Immunity 72 1188-1191 Hajishengallis G, Martin M, Schifferle RE and Genco RJ (2002) Counteracting interactions between lipopolysaccharide molecules with differential activation of Toll-like receptors. Infection & Immunity 70 6658-6664 Hajishengallis G, Nawar H, Tapping RI, Russell MW and Connell TD (2004) The type II heat-labile enterotoxins LT-IIa and LT-IIb and their respective B pentamers differentially induce and regulate cytokine production in human monocytic cells. Infection and Immunity 72 6351-6358 Hajishengallis G, Tapping RI, Martin MH, Nawar H, Lyle EA, Russell MW and Connell TD (2005) Toll-like receptor 2 mediates cellular activation by the B subunits of type II heat-labile enterotoxins. Infection and Immunity 73 1343-1349 Hajra L,
Evans AI, Chen M, Hyduk SJ, Collins T and Cybulsky MI (2000) The NF-kB signal
transduction pathway in aortic endothelial cells is primed for activation in
regions predisposed to atherosclerotic lesion formation. Proceedings of the
National Academy of Sciences USA 97 9052-9057 Hakala
JK, Lindstedt KA, Kovanen PT and Pentikainen MO (2006) Low-density lipoprotein
modified by macrophage-derived lysosomal hydrolases induces expression and
secretion of IL-8 via p38 MAPK and NF-kB by human monocyte-derived
macrophages. Hakansson P, Nilsson B, Andersson A, Lassen C,, Gullberg U and Fioretos T (2008) Gene expression analysis of BCR/ABL1-dependent transcriptional response reveals enrichment for genes involved in negative feedback regulation. Genes, Chromosomes and Cancer in press Hale-Donze H,
Greenwell-Wild T, Mizel D, Doherty TM, Chatterjee D, Orenstein JM and Wahl SM
(2002) Mycobacterium avium complex promotes recruitment of monocyte hosts for
HIV-1 and bacteria. Journal of Immunology 169 3854-3862 Haley M, Cui X, Minneci PC, Deans KJ, Natanson C and Eichacker PQ (2004) Activated protein C in sepsis: emerging insights regarding its mechanism of action and clinical effectiveness. Current Opinion in Infectious Disease 17 205-211 Hall A (2005) Rho GTPases and the control of cell behaviour. Biochem Soc Trans 33 891-895 Hall AJ, Vos
HL and Bertina RM (1999) Lipopolysaccharide induction of tissue factor in
THP-1 cells involves Jun protein phosphorylation and nuclear factor kB nuclear
translocation. Journal of Biological Chemistry 274 376-383 Hall BM,
Fortney JE and Gibson LF (2001) Alteration of Nuclear Factor-kB (NF-kB)
expression in bone marrow stromal cells treated with etoposide. Biochem
Pharmacol 61 1243-1252 Hall BS, Tam
W, Sen R and Pereira ME (2000) Cell-specific activation of nuclear factor-kB
by the parasite Trypanosoma cruzi promotes resistance to intracellular
infection. Molecular Biology of the Cell 11 153-160 Hall DJ, Bates ME, Guar L, Cronan M, Korpi N and Bertics PJ (2005) The role of p38 MAPK in rhinovirus-induced monocyte chemoattractant protein-1 production by monocytic-lineage cells. Journal of Immunology 174 8056-8063 Hall G, Hasday JD and Rogers TB (2006) Regulating the regulator: NF-kB signaling in heart. Journal of Molecular and Cellular Cardiology 41 580-591 Hall G, Shah M, McEwan PA, Laughton C, Stevens M, Westwell A and Emsley J (2006) Structure of Mycobacterium tuberculosisthioredoxin C. Acta Crystallographica Section D Biological Crystallography 62 1453-1457 Hall G, Singh IS, Hester L, Hasday JD and Rogers TB (2005) Inhibitor-kB Kinase-beta regulates LPS-induced TNFalpha production in cardiac myocytes through NF-kB p65 subunit phosphorylation. American Journal of Physiology: Heart and Circulatory Physiology 289 H2103-H2111 Hall
JL, Wang X, Van A, Zhao Y and Gibbons GH (2001) Overexpression of Ref-1 inhibits
hypoxia and tumor necrosis factor- induced endothelial cell apoptosis through
nuclear factor-kB-independent and -dependent pathways. Circulation Research 88
1247-1253 Hall MA and Cleveland JL (20070 Clearing the TRAIL for cancer therapy. Cancer Cell 12 4-6 Hall MW, Gavrilin MA, Knatz NL, Duncan MD, Fernandez SA and Wewers MD (2007) Monocyte mRNA phenotype and adverse outcomes from pediatric multiple organ dysfunction syndrome. Pediatric Research in press Hallahan DE
and Teng M (2000) The proteasome: a molecular target for cancer therapy. Int J Radiat Oncol Biol Phys 47 859-860 Hallahan DE,
Virudachalam S and Kuchibhotla J (1998) Nuclear factor kB dominant negative
genetic constructs inhibit X-ray induction of cell adhesion molecules in the
vascular endothelium. Cancer Research 58 5484-5488 Haller D (2006) Intestinal epithelial cell signalling and host-derived negative regulators under chronic inflammation: to be or not to be activated determines the balance towards commensal bacteria. Neurogastroenterol Motil 18 184-199 Haller D, Holt L, Kim SC, Schwabe RF, Sartor RB and Jobin C (2003) TGF-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kB recruitment to the IL-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation. Journal of Biological Chemistry 278 23851-23860 Haller D, Holt L, Parlesak A, Zanga J, Bauerlein A, Sartor RB and Jobin C (2004) Differential effect of immune cells on non-pathogenic Gram-negative bacteria-induced nuclear factor-kappaB activation and pro-inflammatory gene expression in intestinal epithelial cells. Immunology 112 310-320 Haller D, Russo MP, Sartor RB and Jobin C (2002) IKKb and PI3K/Akt participate in non-pathogenic gram negative enteric bacteria induced RelA phosphorylation and NF-kB activation in both primary and intestinal epithelial cell lines. Journal of Biological Chemistry 277 38168-38178 Haloui M, Meilhac O, Jandrot-Perrus M, Michel JB (2003) Atorvastatin limits the pro-inflammatory response of rat aortic smooth muscle cells to thrombin. European Journal of Pharmacology 474 175-184 Halpern MD, Holubec H, Clark JA, Saunders TA, Williams CS, Dvorak K and Dvorak B (2005) Epidermal growth factor reduces hepatic sequelae in experimental necrotizing Enterocolitis. Biology of the Neonate 89 227-235
Halpern MS,
Wade E, Rucker E, Baxter-Gabbard KL, Levine AS and Friis RR (1973) A study of
the relationship of reticuloendotheliosis virus to the avian leukosis-sarcoma
complex of viruses. Virology 53 287-299 Halsey TA, Yang L, Walker JR, Hogenesch JB and Thomas RS (2007) A functional map of NFkB signaling identifies novel modulators and multiple system controls. Genome Biology 8 R104 Halvey PJ, Hansen JM, Johnson JM, Go YM, Samali A and Jones DP (2007) Selective oxidative stress in cell nuclei by nuclear-targeted D-amino acid oxidase. Antioxidand & Redox Signaling 9 807-816 Halvorsen E,
Dennis J, Keeney P, Sturgill T, Tuttle J and Bennett J (2002) Methylpyridinium
(MPP(+))- and nerve growth factor-induced changes in pro- and anti-apoptotic
signaling pathways in SH-SY5Y neuroblastoma cells. Brain Research 952 98 Hamacher R, Saur D, Fritsch R, Reichert M, Schmid RM and Schneider G (2007) Casein kinase II inhibition induces apoptosis in pancreatic cancer cells. Oncology Reports 18 695-701 Hamacher R, Schmid RM, Saur D and Schneider G (2008) Apoptotic pathways in pancreatic ductal adenocarcinoma. Molecular Cancer in press Hamada H,
Sawyer RT, Kittle LA and Newman LS (2000) Beryllium-stimulation does not
activate transcription factors in a mouse hybrid macrophage cell line.
Toxicology 143 249-261 Hamaguchi E, Takamura T, Shimizu A and Nagai Y (2003) TNF-a and troglitazone regulate plasminogen activator inhibitor type 1(PAI-1) production through ERK- and NF-kB-dependent pathways in cultured human umbilical vein endothelial cells. Journal of Pharmacology and Experimental Therapeutics 307 987-994 Hamalainen M, Nieminen R, Vuorela P, Heinonen M and Moilanen E (2007) Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Mediators of Inflammation 2007 45673 Hamamdzic D,
Phillips-Dorsett T, Altman-Hamamdzic S, London SD and London L (2001) Reovirus
triggers cell type-specific proinflammatory responses dependent on the
autocrine action of IFN-b. American Journal of Physiology: Lung Cell and Molecular Physiology 280 L18-L29 Hamamura RS, Ohyashiki JH, Kurashina R, Kobayashi C, Zhang Y, Takaku T and Ohyashiki K (2007) Induction of heme oxygenase-1 by cobalt protoporphyrin enhances the antitumour effect of bortezomib in adult T-cell leukaemia cells. British Journal of Cancer in press Hamanaka R,
Kohno K, Seguchi T, Okamura K, Morimoto A, Ono M, Ogata J and Kuwano M (1992)
Induction of low density lipoprotein receptor and a transcription factor SP-1
by tumor necrosis factor in human microvascular endothelial cells. Journal of
Biological Chemistry 267 13160-13165 Hamann L, Alexander C, Stamme C, Zahringer U and Schumann RR (2005) Acute-phase concentrations of lipopolysaccharide (LPS)-binding protein inhibit innate immune cell activation by different LPS chemotypes via different mechanisms. Infection and Immunity 73 193-200 Hamann L,
Schumann RR, Flad HD, Brade L, Rietschel ET and Ulmer AJ (2000) Binding of
lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced
NF-kB activation. European Journal of Immunogy 30 211-216 Hamano R, Takahashi HK, Iwagaki H, Yoshino T, Nishibori M and Tanaka N (2006) Stimulation of alpha7 nicotinic acetylcholine receptor inhibits CD14 and the Toll-like receptor 4 expression in human monocytes. Shock 26 358-364 Hamanoue M,
Middleton G, Wyatt S, Jaffray E, Hay RT and Davies AM (1999) p75-mediated
NF-kB activation enhances the survival response of developing sensory neurons
to nerve growth factor. Molecular and Cellular Neuroscience 14 28-40 Hamanoue M, Yoshioka A, Ohashi T, Eto Y and Takamatsu K (2004) NF-kB prevents TNF-a-induced apoptosis in an oligodendrocyte cell line. Neurochemical Research 29 1571-1576 Hamaoka R,
Fujii J, Miyagawa J, Takahashi M, Kishimoto M, Moriwaki M, Yamamoto K,
Kajimoto Y, Yamasaki Y, Hanafusa T, Matsuzawa Y and Taniguchi N (1999)
Overexpression of the aldose reductase gene induces apoptosis in pancreatic
beta-cells by causing a redox imbalance. Journal of Biochemistry (Tokyo) 126 41-47 Hamazaki Y, Fujita H, Kobayashi T, Choi Y, Scott HS, Matsumoto M and Mnato N (2007) Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Nature Immunology in press Hamdane M,
David-Cordonnier M-H and D'Halluin JC (1997) Activation of p65 NF-kB protein
by p210BCR-ABL in a myeloid cell line (p210BCR-ABL activates p65 NF-kB).
Oncogene 15 2267-2275 Hamdi H, Bigorgne A, Naveau S, Balian A, Bouchet-Delbos L, Cassard-Doulcier AM, Maillot MC, Durand-Gasselin I, Prevot S< Delaveaucoupet J, Emilie D and Perlemuter G (2007) Glucocorticoid-induced leucine zipper: A key protein in the sensitization of monocytes to lipopolysaccharide in alcoholic hepatitis. Hepatology 46 1986-1992 Hamer HM, Jonkers D, Venema K, Vanhoutvin S, Troost FJ and Brummer RJ (2007) Review article: the role of butyrate on colonic function. Alimentary Pharmacology and Therapy in press Hamilton TA,
Major JA, Armstrong D and Tebo JM (1998) Oxidized LDL modulates activation of
NFkB in mononuclear phagocytes by altering the degradation of IkBs. Journal of
Leukocyte Biology 64 667-674 Hamilton KL, Mbai FN, Gupta S and Knowlton AA (2004) Estrogen, heat shock proteins, and NF6B in human vascular endothelium. Arteriosclerosis, Thrombosis and Vascular Biology 24 1628-1633 Hammad SM, Twal WO, Barth JL, Smith KJ, Saad AF, Virella G, Schott Agrgraves W and Lopes-Virella MF (2008) Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells. Atherosclerosis in press Hammadi A, Billard C, Faussat AM and Kolb JP (2008) Stimulation of iNOS expression and apoptosis resistance in B-cell chronic lymphocytic leukemia (B-CLL) cells through engagement of Toll-like receptor 7 (TLR-7) and NF-kB activation. Nitric Oxide in press Hammaker D, Sweeney S and Firestein GS (2003) Signal transduction networks in rheumatoid arthritis. Annals of Rheumatoid Disease 62 II86-II89 Hammaond-Kosack
KE and Jones JDG (1997) Plant disease resistance genes. Annual Review of Plant
Physiology and Plant Molecular Biology 48 575-607 Hammar E, Parnaud G, Bosco D, Perriraz N, Maedler K, Donath M, Rouiller DG and Halban PA (2004) Extracellular matrix protects pancreatic {beta}-cells against apoptosis: role of short- and long-term signaling pathways. Diabetes 53 2034-2041 Hammar EB, Irminger JC, RIchenbach K, Parnaud G, Ribaux P, Bosco D, Rouiller DG and Halban PA (2005) Activation of NF-kB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells. Journal of Biological Chemistry 280 30630-30637 Hammarskjöld
M-L and Simurda MC (1992) Epstein-Barr virus latent membrane protein
transactivates the human immunodeficiency virus type 1 long terminal repeat
through induction of NF-kB activity. Journal of Virology 66 6496-6501 Hammer M, Mages J, Dietrich H, Schmitz F, Striebel F, Murray PJ, Wagner H and Lang R (2005) Control of dual-specificity phosphatase-1 expression in activated macrophages by IL-10. European Journal of Immunology 35 2991-3001 Hammer S, Sauer B, Spika I, Schraut C, Kleuser B and Schafer-Korting M (2004) Glucocorticoids mediate differential anti-apoptotic effects in human fibroblasts and keratinocytes via sphingosine-1-phosphate formation. Journal of Cell Biochemistry 91 840-851 Hammerman PS, Fox CJ, Cinalli RM, Xu A, Wagner JD, Lindsten T and Thompson CB (2004) Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kB activation. Cancer Research 64 8341-8348 Hammes HP, Du X, Edelstein D, Taguchi T, Matsumura T, Ju Q, Lin J, Bierhaus A, Nawroth P, Hannak D, Neumaier M, Bergfeld R, Giardino I and Brownlee M (2003) Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nature Medicine 9 294-299 Hammes HP, Hoerauf H, Alt A, Schleicher E, Clausen JT, Bretzel RG and Laqua H (1999) N(epsilon)(carboxymethyl)lysin and the AGE receptor RAGE colocalize in age-related macular degeneration. Invest Ophthalmol Vis Sci 40 1855-1859 Hammond C, Shi Y, Mena J, Tomic J, Cervi D, He L, Millar AE, Debenedette M, Schuh AC, Baryza JL, Wender PA, Radvanyi L and Spaner DE (2004) Effect of serum and antioxidants on the immunogenicity of protein kinase C-activated chronic lymphocytic leukemia cells. Journal of Immunotherapy 28 28-39 Hammond CM, White D, Tomic J, Shi Y and Spaner DE (2007) Extracellular calcium sensing promotes human B cell activation and function. Blood 110 3985-3995 Hammond LC, Bonnet C, Kemp PJ, Yates MS and Bowmer CJ (2004) Chronic hypoxia up-regulates expression of adenosine A1 receptors in DDT1-MF2 cells. Biochemical Pharmacology 67 421-426 Hampe J,
Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S, Frenzel H, King K,
Hasselmeyer A, MacPherson AJ, Bridger S, van Deventer S, Forbes A, Nikolaus S,
Lennard-Jones JE, Foelsch UR, Krawczak M, Lewis C, Schreiber S and Mathew CG
(2001) Association between insertion mutation in NOD2 gene and Crohn's disease
in German and British populations. Lancet 357 1925-1928 Hampson L,
Hampson IN, Babichuk CK, Cotter L, Bleackley RC, Dexter TM and Cross MA (2001)
A minimal serpin promoter with high activity in haematopoietic progenitors and
activated T cells. Hematology Journal 2 150-160 Hams E, Colmont CS, Dioszeghy V, Hammond VJ, Fielding CA, WIlliams AS, Tanaka M, Miyajima A, Taylor PR, Topley N and Jones SA (2008) Oncostatin M receptor-b signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 2174-2180 Hamuro M,
Polan J, Natarajan M and Mohan S (2002) High glucose induced nuclear factor
kappa B mediated inhibition of endothelial cell migration. Atherosclerosis 162
277-287 Han B and
Logsdon CD (1999) Cholecystokinin induction of mob-1 chemokine expression in
pancreatic acinar cells requires NF-kB activation. American Journal of
Physiology 277 C74-C82 Han B and
Logsdon CD (2000) CCK stimulates mob-1 expression and NF-kB activation via
protein kinase C and intracellular Ca(2+). American Journal of Physiology Cell
Physiology 278 C344-C351 Han B, Ji B
and Logsdon CD (2001) CCK independently activates intracellular trypsinogen
and NF-kB in rat pancreatic acinar cells. American Journal of Physiology Cell
Physiology 280 C465-C472 Han B, Mura M, Andrade CF, Okutani D, Lodyga M, Dos Santos CC, Keshavjee S, Matthay M and Liu M (2005) TNFalpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK. Journal of Immunology 175 8303-8311 Han
CW, Choi
JH, Kim JM, Kim WY, Lee KY and Oh GT (2001) Glucocorticoid-mediated repression
of inflammatory cytokine production in fibroblast-like rheumatoid synoviocytes
is independent of nuclear factor-kB activation induced by tumour necrosis
factor alpha. Rheumatology (Oxford) 40 267-273 Han CY, Chiba T, Campbell JS, Fausto N, Chaisson M, Orasanu G, Plutzky J and Chait A (2006) Reciprocal and coordinate regulation of serum amyloid A versus apolipoprotein A-I and paraoxonase-1 by inflammation in murine hepatocytes. Arteriosclerosis, Thrombosis and Vascular Biology 26 1806-1813 Han D, Hanawa N, Saberi B and Kaplowitz N (2006) Role of glutathione redox status in liver injury. American Journal of Physiology: Gastrointestinal and Liver Physiology 291 G1-G7 Han D, Hanawa N, Saberi B and Kaplowitz N (2006) Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis. Free Radical Biology and Medicine 41 627-39 Han DW, Lim HR, Baek HS, Lee MH, Lee SJ, Hyon SH and Park JC (2006) Inhibitory effects of epigallocatechin-3-O-gallate on serum-stimulated rat aortic smooth muscle cells via nuclear factor-kB down-modulation. Biochemical and Biophysical Research Communications 345 148-155 Han EH, Hwang YP, Kim HG and Jeong HG (2007) Inflammatory effect of endosulfan via NF-kB activation in macrophages. Biochemical and Biophysical Research Communications 355 860-865 Han EH, Hwang YP, Lee KJ, Jeong TC and Jeong HG (2007) 1-Bromopropane induces macrophage activation via extracellular signal-regulated kinase 1/2 MAPK and NF-kB pathways. Cancer Letters in press Han H, Jeon Y and Lee Y (2003) Involvement of NF-kB in high glucose-induced alteration of a-methyl-D-glucopyranoside (alpha-MG) uptake in renal proximal tubule cells. Cell Physiol Biochem 13 375-384 Han HJ, Lee YJ, Park SH, Lee JH and Taub M (2004) High glucose-induced oxidative stress inhibits Na+/glucose cotransporter activity in renal proximal tubule cells. American Journal of Physiology: Renal Physiology 288 F988-F996 Han HJ, Lim MJ, Lee YJ, Lee JH, Yang IS and Taub M (2007) Uric acid inhibits renal proximal tubule cell proliferation via at least two signaling pathways involving PKC, MAPK, cPLA2, and NF-kB. American Journal of Physiology: Renal Physiology 292 F373-F381 Han HJ, Oh YJ and Lee YJ (2005) Effect of albumin on (14)C-alpha-Methyl-d-Glucopyranoside uptake in primary cultured renal proximal tubule cells: Involvement of PLC, MAPK, and NF-kB. Journal of Cell Physiology 202 246-254 Han HS, Karabiyikoglu M, Kelly S, Sobel RA and Yenari MA (2003) Mild hypothermia inhibits nuclear factor-kB translocation in experimental stroke. J Cereb Blood Flow Metab 23 589-598 Han IO, Kim HS, Kim HC, Joe EH and Kim WK (2003) Synergistic expression of inducible nitric oxide synthase by phorbol ester and interferon-gamma is mediated through NF-kB and ERK in microglial cells. Journal of Neuroscience Research 73 659-669 Han J, Kim M, Oum JH, Myung H, Lee SW, Jeong S, Sharma S and Park J (2002) RACK-1, a receptor for activated C kinase, interacts with the transcription factor NFAT and represses its transactivation. Molecules and Cells 14 420-424 Han J, Parsons M, Zhou X, Nicholson AC, Gotto AM Jr and Hajjar DP (2004) Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104). Circulation 110 3472-3479 Han J, Sun M, Cui Y, Wang T, Zhang W, Guo M, Zhou Y, Liu W, Zhang M, Duan J, Xiong S, Yao M and Yan X (2007) Kushen flavonoids induce apoptosis in tumor cells by inhibition of NF-kB activation and multiple receptor tyrosine kinase activities. Phytotherapy Research 21 262-268 Han JC, Zhang KL, Chen XY, Jiang HF, Kong QY, Sun Y, Wu ML, Huang L, Li H and Liu J (2007) Expression of seven gastric cancer-associated genes and its relevance for Wnt, NF-kB and Stat3 signaling. APMIS 115 1331-1343
Han JH, Choi
SJ, Kurihara N, Koide M, Oba Y and Roodman GD (2001) Macrophage inflammatory
protein-1alpha is an osteoclastogenic factor in myeloma that is independent of
receptor activator of nuclear factor kB ligand. Blood 97 3349-3353 Han JM, Lee WS, Kim JR, Son J, Kwon OH, Lee HJ, Lee JJ and Jeong TS (2008) Effect of 5-O-Methylhirsutanonol on nuclear factor-kB-dependent production of NO and expression of iNOS in lipopolysaccharide-induced RAW264.7 cells. Journal of Agricultural Food Chemistry 56 92-98 Han JM, Lee WS, Kim JR, Son J, Nam KH, Choi SC, Lim JS and Jeong TS (2007) Effects of diarylheptanoids on the tumor necrosis factor-a-induced expression of adhesion molecules in human umbilical vein endothelial cells. Journal of Agricultural Food Chemistry 55 9457-9464 Han JY, Heo JS, Lee YJ, Lee JH, Taub M and Han HJ (2007) Dopamine stimulates (45)Ca(2+) uptake through cAMP, PLC/PKC, and MAPKs in renal proximal tubule cells. Journal of Cellular Physiology 211 486-494 Han KH, Hong KH, Ko J, Rhee KS, Hong MK, Kim JJ, Kim YH and Park SJ (2004) Lysophosphatidylcholine up-regulates CXCR4 chemokine receptor expression in human CD4 T cells. Journal of Leukocyte Biology 76 195-202 Han KJ, Su X, Xu LG, Bin LH, Zhang J and Shu HB (2004) Mechanisms of TRIF-induced ISRE and NF-kB activation and apoptosis pathways. Journal of Biological Chemistry 279 15652-15661 Han KY, Kwon TH, Lee TH, Lee SJ, Kim SH and Kim J (2008) Suppressive effects of Lithospermum erythrorhizon extracts on lipopolysaccharide-induced activation of AP-1 and NF-kB via mitogen-activated protein kinase pathways in mouse macrophage cells. BMB Reports 41 328-333 Han KY, Yang D, Chang EJ, Lee Y, Huang H, Sung SH, Lee ZH, Kim YC and Kim HH (2007) Inhibition of osteoclast differentiation and bone resorption by sauchinone. Biochemical Pharmacology 74 911-923 Han M, Wen JK, Zheng B and Zhang DQ (2004) Acetylbritannilatone suppresses NO and PGE(2) synthesis in RAW 264.7 macrophages through the inhibition of iNOS and COX-2 gene expression. Life Sciences 75 675-684 Han MH, Yoon WK, Lee H, Han SB, Lee K, Park SK, Yang KH, Kim HM and Kang JS (2007) Topical application of silymarin reduces chemical-induced irritant contact dermatitis in BALB/c mice. International Immunopharmacology 7 1651-1658 Han MK (2003) Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage. Experimental and Molecular Medicine 35 136-139 Han MK, Kim JS, Park BH, Kim JR, Hwang BY, Lee HY, Song EK and Yoo WH (2003) NF-kB-dependent lymphocyte hyperadhesiveness to synovial fibroblasts by hypoxia and reoxygenation: potential role in rheumatoid arthritis. Journal of Leukocyte Biology 73 525-529 Han S, Inoue H, Flowers LC and Sidell N (2003) Control of COX-2 gene expression through peroxisome proliferator-activated receptor gamma in human cervical cancer cells. Clinical Cancer Research 9 4627-4635 Han S, Ritzenthaler JD, Zheng Y and Roman J (2008) PPARbeta/delta agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3-K and NF-kB signals. American Journal of Physiology: Cell and Molecular Physiology 294 L1238-L1249 Han S and Roman J (2006) Rosiglitazone suppresses human lung carcinoma cell growth through PPARg-dependent and PPARg-independent signal pathways. Molecular Cancer Therapy 5 430-437 Han S and Sidell N (2003) RU486-induced growth inhibition of human endometrial cells involves the nuclear factor-kB signaling pathway. Journal of Clinical Endocrinology and Metabolism 88 713-719 Han S, Sidell N, Fisher PB and Roman J (2004) Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells. Clinical Cancer Research 10 1911-1919 Han S, Yoon K, Lee K, Kim K, Jang H, Lee NK, Hwang K and Young Lee S (2003) TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kB through TNF receptor-associated factors. Biochemical and Biophysical Research Communications 305 789-796 Han SB, Yoon YD, Ahn HJ, Lee HS, Lee CW, Yoon WK, Park SK and Kim HM (2003) Toll-like receptor-mediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus. International Immunopharmacology 3 1301-1312
Han SH, Jeon
YJ, Yea SS and Yang KH (1999) Suppression of the interleukin-2 gene expression
by aflatoxin B1 is mediated through the down-regulation of the NF-AT and AP-1
transcription factors. Toxicology Letters 108 1-10 Han SJ, Choi
JH, Ko HM, Yang HW, Choi IW, Lee HK, Lee OH and Im SY (1999) Glucocorticoids
prevent NF-kB activation by inhibiting the early release of platelet-activating factor in response to lipopolysaccharide. European Journal
of Immunology 29 1334-1341 Han SJ, Jeong SY, Nam YJ, Yang KH, Lim HS and Chung J (2005) Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clin Diagn Lab Immunol 12 1285-1291 Han SJ, Ko HM, Choi JH, Seo KH, Lee HS, Choi EK, Choi IW, Lee HK and Im SY (2002) Molecular mechanisms for LPS-induced biphasic activation of NF-kB. Journal of Biological Chemistry 277 44715-44721 Han SS, Chung
ST, Robertson DA, Chelvarajan RL and Bondada S (1999) CpG
oligodeoxynucleotides rescue BKS-2 immature B cell lymphoma from
anti-IgM-mediated growth inhibition by up-regulation of egr-1. International
Immunology 11 871-879 Han SS, Chung
ST, Robertson DA, Ranjan D and Bondada S (1999) Curcumin causes the growth
arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc,
bcl-XL, NF-kB, and p53. Clinical Immunology 93 152-161 Han SS, Keum
Y, Seo H, Chun K, Lee SS, Surh Y (2001) Capsaicin suppresses phorbol
ester-induced activation of NF-kB/Rel and AP-1 transcription factors in mouse
epidermis. Cancer Letters 164 119-126 Han SS, Keum
YS, Chun KS and Surh YJ (2002) Suppression of phorbol ester-induced NF-kB
activation by capsaicin in cultured human promyelocytic leukemia cells. Arch
Pharm Res 25 475-479 Han SS, Keum
YS, Seo HJ and Surh YJ (2002) Curcumin suppresses activation of NF-kB and AP-1
induced by phorbol ester in cultured human promyelocytic leukemia cells. J
Biochem Mol Biol 35 337-342 Han SS, Keum
YS, Seo HJ, Chun KS, Lee SS and Surh YJ (2001) Capsaicin suppresses phorbol
ester-induced activation of NF-kB/Rel and AP-1 transcription factors in mouse
epidermis. Cancer Letters 164 119-126 Han SS, Kim K, Hahm ER, Lee SJ, Surh YJ, Park HK, Kim WS, Jung CW, Lee MH, Park K, Yang JH, Yoon SS, Riordan NH, Riordan HD, Kimler BF, Park CH, Lee JH and Park S (2004) L-ascorbic acid represses constitutive activation of NF-kB and COX-2 expression in human acute myeloid leukemia, HL-60. Journal of Cellular Biochemistry 93 257-270 Han SS, Kim K, Hahm ER, Park CH, Kimler BF, Lee SJ, Lee SH, Kim WS, Jung CW, Park K, Kim J, Yoon SS, Lee JH and Park S (2005) Arsenic trioxide represses constitutive activation of NF-kB and COX-2 expression in human acute myeloid leukemia, HL-60. J Cell Biochem 94 695-707 Han SS, Peng L, Chung St, Dubois W, Maeng SH, Shaffer AL, Sporn MB and Janz S (2006) CDDO-imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms. Molecular Cancer 5 22 Han SS, Shaffer AL, Peng L, Chung ST, Lim JH, Maeng S, Kim JS, McNeil N, Ried T, Staudt LM and Janz S (2005) Molecular and cytological features of the mouse B-cell lymphoma line iMycEm-1. Molecular Cancer 4 40 Han SW and Roman J (2006) Fibronectin induces cell proliferation and inhibits apoptosis in human bronchial epithelial cells: pro-oncogenic effects mediated by PI3-kinase and NF-kB. Oncogene 25 4341-4349 Han SY, Kim CH, Kim HS, Jee YH, Song HK, Lee MH, Han KH, Kim HK, Kang YS, Han JY, Kim YS and Cha DR (2006) Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Journal of the American Soceiety of Nephrology 17 1362-1372 Han SY, Lee NK, Kim KH, Jang IW, Yim M, Kim JH, Lee WJ and Lee SY (2005) Transcriptional induction of cyclooxygenase-2 in osteoclast precursors is involved in RANKL-induced osteoclastogenesis. Blood 106 1240-1245 Han X, Benight N, Osuntokun B, Loesch K, Frank S and Denson L (2007) Tumour necrosis factor alpha blockade induces an anti- inflammatory growth hormone signalling pathway in experimental colitis. Gut 56 73-81 Han X, Fink MP, Uchiyama T and Delude RL (2004) Increased iNOS activity is essential for the development of pulmonary epithelial tight junction dysfunction in endotoxemic mice. American Journal of Physiology: Lung Cell and Molecular Physiology 286 G126-G136 Han X, Kawai T, Eastcott JW and Taubman MA (2006) Bacterial-responsive B lymphocytes induce periodontal bone resorption. Journal of Immunology 176 625-631
Han X, Sun Y,
Scott S and Bleich D (2001) Tissue inhibitor of metalloproteinase-1 prevents
cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and
beta-cells. Diabetes 50 1047-1055 Han X, Uchiyama T, Sappington PL, Yaguchi A, Fink MP and Delude RL (2003) NAD+ ameliorates inflammation-induced epithelial barrier dysfunction in cultured enterocytes and mouse ileal mucosa. Journal of Pharmacology and Experimental Therapy 307 443-449 Han Y and Brasier AR (1997) Mechanism for biphasic relA. NF-kB1 nuclear translocation in tumor necrosis factor alpha-stimulated hepatocytes. Journal of Biological Chemistry 272 9825-9832 Han Y, Englert JA, Delude RL and Fink MP (2005) Ethacrynic acid inhibits multiple steps in the NF-kB signaling pathway. Shock 23 45-53 Han Y, Englert JA, Delude RL and Fink MP (2004) Ethacrynic Acid inhibits multiple steps in the nfkb signaling pathway. Critical Care Medicine 32 A16 Han Y, Englert JA, Yang R, Delude RL and Fink MP (2005) Ethyl pyruvate inhibits NF-kB-dependent signaling by directly targeting p65. Journal of Pharmacology and Experimental Therapy 312 1097-1105 Han Y, Englert JA, Yang R, Delude RL and Fink MP (2004) Ethyl pyruvate inhibits NF-kB dependent signaling by targeting p65. Critical Care Medicine 32 A15 Han Y, He T,
Huang DR, Pardo CA and Ransohoff RM (2001) TNF-alpha mediates SDF-1
alpha-induced NF-kB activation and cytotoxic effects in primary astrocytes.
Journal of Clinical Investigation 108 425-435 Han Y, Meng
T, Murray NR, Fields AP and Brasier AR (1999) Interleukin-1-induced nuclear
factor-kB-IkBa autoregulatory feedback loop in hepatocytes: a role for protein
kinase Ca in post-transcriptional regulation of IkBa resynthesis. Journal of
Biological Chemistry 274 939-947 Han Y, Runge
MS and Brasier AR (1999) Angiotensin II induces interleukin-6 transcription in
vascular smooth muscle cells through pleiotropic activation of nuclear
factor-kB transcription factors. Circulation Research 84 695-703 Han Y,
Weinman S, Boldogh I, Walker RK and Brasier AR (1999) Tumor necrosis
factor-alpha-inducible IkBa proteolysis mediated by cytosolic m-calpain. A
mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kB
activation. Journal of Biological Chemistry 274 787-794 Han YH, Kwon JH, Yu DY and Moon EY (2006) Inhibitory effect of peroxiredoxin II (Prx II) on Ras-ERK-NFkB pathway in mouse embryonic fibroblast (MEF) senescence. Free Radical Research 40 1182-1189 Han Z, Boyle
DL, Manning AM and Firestein GS (1998) AP-1 and NF-kB regulation in rheumatoid
arthritis and murine collagen-induced arthritis. Autoimmunity 28 197-208 Han ZS and Ip
YT (1999) Interaction and specificity of Rel-related proteins in regulating
Drosophila immunity gene expression. Journal of Biological Chemistry 274
21355-21361 Han ZS,
Enslen H, Hu X, Meng X, Wu I-H, Barrett T, Davis RJ and Ip YT (1998) A
conserved p38 mitogen-activated protein kinase pathway regulates Drosophila
immunity gene expression. Molecular and Cellular Biology 18 3527-3539 Hanada T, Kobayashi T, Chinen T, Saeki K, Takaki H, Koga K, Minoda Y, Sanada T, Yoshioka T, Mimata H, Kato S and Yoshimura A (2006) IFNg-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice. Journal of Experimental Medicine 203 1391-1397 Hanamura I (2007) The molecular pathogenesis of myeloma for the therapeutic targets [Article in Japanese]. Nippon Rinsho 65 2202-2208 Hanashiro K, Sunagawa M, Tokeshi Y, Nakasone T, Ohta S, Nakamura M and Kosugi T (2006) Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells. European Journal of Pharmacology 547 174-183 Hanauer
SB (2000) Medical therapy for ulcerative colitis. Hanazawa S (2001) Risk factors that modulate periodontal diseases [Article in Japanese]. Clinical Calcium 11 319-321 Hand RA and Craven RJ (2003) Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 human breast cancer cells. Jounral of Cellular Biochemistry 90 534-547 Handa O, Naito Y, Takagi T, Shimozawa M, Kokura S, Yoshida N, Matsui H, Cepinskas G, Kvietys PR and Yoshikawa T (2004) TNF-a-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of ROS and NFkB. Journal of Pharmacology and Experimental Therapy 309 670-676 Haneji K, Matsuda T, Tomita M, Kawakami H, Ohshiro K, Uchihara JN, Masuda M, Takasu N, Tanaka Y, Ohta T and Morin N (2005) Fucoidan extracted from cladosiphon okamuranus tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Nutr Cancer 52 189-201 Handel-Fernandez
ME and Vincek V (1999) Sequence analysis and expression of a mouse homolog of
the human IkBL gene. Biochimica et Biophysica Acta 1444 306-310 Hanefeld M and Schaper F (2004) Postprandial hyperglycemia as a risk factor for cardiovascular disease. Therapy improves prognosis [Article in German]. Herz 29 480-487 Hang CH, Chen G, Shi JX, Zhang X and Li JS (2006) Cortical expression of nuclear factor kB after human brain contusion. Brain Research in press1109 14-21 Hang CH, Shi JX, Li JS, Li WQ and Wu W (2005) Expressions of intestinal NF-kB, TNF-a, and IL-6 following traumatic brain injury in rats. Journal of Surgical Research 123 188-193 Hang CH, Shi JX, Li JS, Li WQ and Yin HX (2005) Up-regulation of intestinal nuclear factor kB and intercellular adhesion molecule-1 following traumatic brain injury in rats. World Journal of Gastroenterology 11 1149-1154 Hang CH, Shi JX, Li JS, Wu W and Yin HX (2005) Concomitant upregulation of nuclear factor-kB activity, proinflammatory cytokines and ICAM-1 in the injured brain after cortical contusion trauma in a rat model. Neurology India 53 312-317 Hang CH, Shi JX, Tian J, Li JS, Wu W and Yin HX (2004) Effect of systemic LPS injection on cortical NF-kB activity and inflammatory response following traumatic brain injury in rats. Brain Reearch 1026 23-32 Hanna H,
Wolff B and Lindley IJD (1998) 1a,25-dyhydroxyvitamin D3 decreases DNA binding
of nuclear factor-kB in human fibroblasts. FEBS Letters 436 329-334 Hannibal MC,
Markovitz DM, Clark N and Nabel GJ (1993) Differential activation of human
immunodeficiency virus type 1 and 2 transcription by specific T-cell
activation signals. Journal of Virology 67 5035-5040 Hannink M and
Temin HM (1989) Transactivation of gene expression by nuclear and cytoplasmic
rel proteins. Molecular and Cellular Biology 9 4323-4336 Hannink M and
Temin HM (1990) Structure and autoregulation of the c-rel promoter. Oncogene 5
1843-1850 Hannink M and
Temin HM (1991) Molecular mechanisms of transformation by the v-rel oncogene.
Critical Reviews in Oncogenesis 2 293-309 Hannink M and
Temin HM (1991) Mutation-driven evolution of Rev-T. In Growth Regulation and
Carcinogenesis (Paukovits WR, ed) CRC Press, Inc, New York NY, p 99-109 Hanriot D, Bello G, Ropars A, Seguin-Devaux C, Poitevin G, Grosjean S, Latger-Cannard V, Devaux Y, Zannad F, Regnault V, Lacolley P, Mertes PM, Hess K and Longrois D (2008) C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor alpha, on human monocytes. Thrombosis and Haemostosis 99 558-569 Hansberger MW, Campbell JA, Danthi P, Arrate P, Pennington KN, Marcu KB, Ballard DW and Dermody TS (2007) IkB kinase subunits alpha and gamma are required for activation of NF-kB and induction of apoptosis by mammalian reovirus. Journal of Virology 81 1360-1371 Hansen JM,
Gong SG, Philbert M and Harris C (2002) Misregulation of gene expression in
the redox-sensitive NF-kB-dependent limb outgrowth pathway by thalidomide. Devopmental
Dynamics 225 186-194 Hansen JM and Harris C (2004) A novel hypothesis for thalidomide-induced limb teratogenesis: redox misregulation of the NF-kB pathway. Antioxidant and Redox Signaling 6 1-14 Hansen JM, Moriarty-Craige S and Jones DP (2007) Nuclear and cytoplasmic peroxiredoxin-1 differentially regulate NF-kB activities. Free Radical Biology and Medicine 43 282-278 Hansen JM, Zhang H and Jones DP (2006) Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-a-induced ROS generation, NF-kB activation and apoptosis. Toxicology Sciences 91 643-650 Hansen SK,
Baeuerle PA and Blasi PA (1994) Purification, reconstitution, and IkB
association of the c-Rel-p65 (RelA) complex, a strong activator of
transcription. Molecular and Cellular Biology 14 2593-2603 Hansen SK,
Nerlov C, Zabel U, Verde P, Johnsen M, Baeuerle PA and Blasi PA (1992) A novel
complex between the p65 subunit of NF-kB and c-Rel binds to a DNA element
involved in the phorbol ester induction of the human urokinase gene. EMBO
Journal 11 205-213 Hanson JC, Bostick MK, Campe CB, Kodali P, Lee G, Yan J and Maher JJ (2006) Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin toxicity. Journal of Hepatology 44 359-367 Hanson JL, Anest V, Reuther-Madrid J and Baldwin AS (2003) Oncoprotein suppression of TNF-induced NF-kB activation is independent of Raf-controlled pathways. Journal of Biological Chemistry 278 34910-34917 Hanson JL, Hawke NA, Kashatus D and Baldwin AS (2004) The nuclear factor kB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation. Cancer Research 64 7248-7255 Hansson A, Marin YE, Suh J, Rabson AB, Chen S, Huberman E, Chang RL, Conney AH and Zheng X (2005) Enhancement of TPA-induced growth inhibition and apoptosis in myeloid leukemia cells by BAY 11-7082, an NF-kB inhibitor. International Journal of Oncology 27 941-948 Hao JH, Hao XS, Yu M, Shi YR and Yang Y (2006) Study on the potential mechanisms of leukemia cell resistance to TRAIL-induced apoptosis [Article in Chinese]. Zhonghua Xue Ye Xue Za Zhi 27 379-382 Hao LN, Ling YQ, Luo XM, Mao YX, Mao QY, He SZ and Ling YL (2006) Puerarin decreases lens epithelium cell apoptosis induced partly by peroxynitrite in diabetic rats. Sheng Li Xue Bao 58 584-592 Hao Q and Maret W (2005) Imbalance between pro-oxidant and pro-antioxidant functions of zinc in disease. Journal of Alzheimers Disease 8 161-170 Hao XS, Hao JH, Liu FT, Newland AC and Jia L (2003) Potential mechanisms of leukemia cell resistance to TRAIL-induced apopotosis. Apoptosis 8 601-607 Haouzi D, Baghdiguian S, Granier G, Travo P, Mangeat P and Hibner U (2005) Three-dimensional polarization sensitizes hepatocytes to Fas/CD95 apoptotic signalling. Journal of Cell Science 118 2763-2773 Haq E, Giri S, Singh I and Singh AK (2003) Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line. Journal of Neurochemistry 86 1428-1440 Hara DB, Leite DF, Fernandes ES, Passos GF, Guimaraes AO, Pesquero JB, Campos MM and Calixto JB (2008) The relevance of kinin B(1) receptor upregulation in a mouse model of colitis. British Journal of Pharmacology in press Hara H, Bakal C, Wada T, Bouchard D, Rottapel R, Saito T and Penninger JM (2004) The molecular adapter Carma1 controls entry of IkB kinase into the central immune synapse. Journal of Experimental Medicine 200 1167-1177 Hara H, Ishihara C, Takeuchi A, Imanishi T, Xue L, Morris SW, Inui M, Takai T, Shibuya A, Saijo S, Iwakura Y, Ohno N, Koseki H, Yoshida H, Penninger JM and Saito T (2007) The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors. Nature Immunology 8 619-629 Hara H, Ishihara C, Takeuchi A, Xue L, Penninger JM, Yoshida H and Saito T (2008) Cell type-specific regulation of ITAM-mediated NF-kB activation by the adaptors, CARMA1 and CARD9. Journal of Immunology 181 918-930 Harada C, Harada T, Mitamura Y, Quah HM, Ohtsuka K, Kotake S, Ohno S, Wada K, Takeuchi S and Tanaka K (2004) Diverse NF-kB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy. Molecular Vision 10 31-36 Harada C, Mitamura Y and Harada T (2006) The role of cytokines and trophic factors in epiretinal membranes: Involvement of signal transduction in glial cells. Progress in Retinal and Eye Research 25 149-164 Harada C, Okumura A, Namekata K, Nakamura K, Mitamura Y, Ohguro H and Harada T (2006) Role of monocyte chemotactic protein-1 and nuclear factor kB in the pathogenesis of proliferative diabetic retinopathy. Diabetes Research and Clinical Practice 74 249-256 Harada K, Isse K, Kamihira T, Shimoda S and Nakanuma Y (2005) Th1 cytokine-induced downregulation of PPARgamma in human biliary cells relates to cholangitis in primary biliary cirrhosis. Hepatology 41 1329-1338 Harada K, Isse K and Nakanuma Y (2006) Interferon gamma accelerates NF-kB activation of biliary epithelial cells induced by Toll-like receptor and ligand interaction. Journal of Clinical Pathology 59 184-190 Harada K, Isse K, Sato Y, Ozaki S and Nakanuma Y (2006) Endotoxin tolerance in human intrahepatic biliary epithelial cells is induced by upregulation of IRAK-M. Liver International 26 935-942
Harada K, Ohira S, Isse K, Ozaki S, Zen Y, Sato Y and Nakanuma Y (2003)
Lipopolysaccharide activates nuclear factor-kB through Toll-like receptors and
related molecules in cultured biliary epithelial cells.
Laboratory
Investigation 83 1657-1667 Harada K, Sato Y, Itatsu K, Isse K, Ikeda H, Yasoshima M, Zen Y, Matsui A and Nakanuma Y (2007) Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia. Hepatology 46 1146-1154 Harada K, Supriatno, Kawashima Y, Yoshida H and Sato M (2007) S-1 inhibits tumorigenicity and angiogenesis of human oral squamous cell carcinoma cells by suppressing expression of phosphorylated Akt, vascular endothelial growth factor and fibroblast growth factor-2. International Journal of Oncology 30 365-374 Harada K, Supriatno, Yoshida H and Sato M (2005) Vesnarinone inhibits angiogenesis and tumorigenicity of human oral squamous cell carcinoma cells by suppressing the expression of vascular endothelial growth factor and interleukin-8. International Journal of Oncology 27 1489-1497
Harada N, Hatano E, Koizumi N, Nitta T, Yoshida M, Yamamoto N, Brenner DA and
Yamaoka Y (2004) Akt activation protects rat liver from ischemia/reperfusion
injury. Journal of Surgical Research 121 159-170 Harada Y, Ohgai D, Watanabe R, Okano K, Koiwai O, Tanabe K, Toma H, Altman A and Abe R (2003) A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS). Journal of Experimental Medicine 197 257-262 Haraga A and Miller SI (2003) A Salmonella enterica serovar typhimurium translocated leucine-rich repeat effector protein inhibits NF-kB-dependent gene expression. Infection & Immunity 71 4052-4058 Harakeh S, Diab-Assaf M, Abu-El-Ardat K, Niedzwiecki A and Rath M (2006) Mechanistic aspects of apoptosis induction by l-lysine in both HTLV-1-positive and -negative cell lines. Chemico-Biological Interactions 164 102-114 Haralambous E, Dolly SO, Hibberd ML, Litt DJ, Udalova IA, O'Dwyer C, Langford PR, Kroll JS and Levin M (2006) Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients. Scandinvaian Journal of Infectious Disease 38 764-771
Harant H,
Eldershaw SA and Lindley IJ (2001) Human macrophage inflammatory
protein-3alpha/CCL20/LARC/Exodus/SCYA20 is transcriptionally upregulated by
tumor necrosis factor-alpha via a non-standard NF-kB site. FEBS Letters 509
439-445 Harant H and Lindley IJ (2004) Negative cross-talk between the human orphan nuclear receptor Nur77/NAK-1/TR3 and nuclear factor-kB. Nucleic Acids Research 32 5280-5290
Harant H,
Wolff B and Lindley IJD (1998) 1a,25-dihydroxyvitamin D3 decreases DNA binding
of nuclear factor-kB in human fibroblasts. FEBS Letters 436 329-334 Harari OA, Alcaide P, Ahl D, Luscinskas FW and Liao JK (2006) Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway. Circulation Research 98 1134-1140 Harbrecht BG,
Taylor BS, Xu Z, Ramalakshmi S, Ganster RW and Geller DA (2001) cAMP inhibits
inducible nitric oxide synthase expression and NF-kB- binding activity in
cultured rat hepatocytes. Journal of Surgical Research 99 258-264 Harcourt BH,
Rota PA, Hummel KB, Bellini WJ and Offermann MK (1999) Induction of
intercellular adhesion molecule 1 gene expression by measles virus in human
umbilical vein endothelial cells. Journal of Medical Virology 57 9-16 Harding P, Balasubramanian L, Swegan J, Stevens A and Glass WF (2006) Transforming growth factor beta regulates cyclooxygenase-2 in glomerular mesangial cells. Kidney International 69 1578-1585 Hardman MJ, Waite A, Zeef L, Burow M, Nakayama T and Ashcroft GS (2005) Macrophage migration inhibitory factor: a central regulator of wound healing. American Journal of Pathology 167 1561-1574 Hardwick JC,
van den Brink GR, Offerhaus GJ, van Deventer SJ and Peppelenbosch MP (2001)
NF-kB, p38 MAPK and JNK are highly expressed and active in the stroma of human
colonic adenomatous polyps. Oncogene 20 819-827 Hardy DB, Janowski BA, Chen CC and Medelson CR (2008) Progesterone receptor (PR) inhibits aromatase and inflammatory response pathways in breast cancer Cells via ligand-Dependent and ligand-independent mechanisms. Molecular Endocrinology in press Hardy DB, Janowski BA, Corey DR and Mendelson CR (2006) Progesterone receptor (PR) plays a major anti-inflammatory role in human myometrial cells by antagonism of NF-kB activation of cyclooxygenase 2 (COX-2) expression. Molecular Endocrinology in press Hardy K and Hunt NH (2004) Effects of a redox-active agent on lymphocyte activation and early gene expression patterns. Free Radical Biology and Medicine 37 1550-1563 Hardy K, Mansfield L, Mackay A, Benvenuti S, Ismail S, O'hare MJ and Jat PS (2005) Transcriptional networks and cellular senescence in human mammary fibroblasts. Molecular and Cellular Biology 16 943-953 Hardy MP, McGettrick AF and O'Neill LA (2004) Transcriptional regulation of the human TRIF gene. Biochemical Journal 380 83-93 Hardy MP and O'Neill LA (2004) The murine Irak2 gene encodes four alternatively spliced isoforms, two of which are inhibitory. Journal of Biological Chemistry 279 27699-27708 Hargett D, Rice S and Bachenheimer SL (2006) Herpes simplex virus types I ICP27-dependent activation of NF-kB. Journal of Virology in press Hargrave BY, Tiangco DA, Lattanzio FA and Beebe SJ (2003) Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-kB in transiently cotransfected heart cells. Cardiovascular Toxicology 3 141-152 Harhaj E,
Blaney J, Millhouse S and Sun S-C (1996) Differential effects of IkB molecules
on Tat-mediated transactivation of HIV-1 LTR. Virology 216 284-287 Harhaj E,
Maggirwar SB and Sun S-C (1996) Inhibition of p105 processing by NF-kB
proteins in transiently transfected cells. Oncogene 12 2385-2392 Harhaj E,
Maggirwar SB, Good L and Sun S-C (1996) CD28 mediates a potent costimulatory
signal for rapid degradation of IkBb which is associated with accelerated
activation of various NF-kB/Rel heterodimers. Molecular and Cellular Biology
16 6736-6743 Harhaj EW and
Sun S-C (1998) IkBkinases serve as a target of CD28 signaling. Journal of
Biological Chemistry 273 25185-25190 Harhaj EW and
Sun S-C (1999) IKKg serves as a docking subunit of the IkB kinase (IKK) and
mediates interaction of IKK with the human T-cell leukemia virus Tax protein.
Journal of Biological Chemistry 274 22911-22914 Harhaj EW and
Sun S-C (1999) Regulation of RelA subcellular localization by a putative
nuclear export signal and p50. Molecular and Cellular Biology 19 7088-7095 Harhaj EW,
Good L, Xiao G and Sun S-C (1999) Gene expression profiles in
HTLV-I-immortalized cells: deregulated expression of genes involved in
apoptosis regulation. Oncogene 18 1341-1349 Harhaj EW,
Good L, Xiao G, Uhlik M, Cvijic ME, Rivera-Walsh I and Sun S-C (2000) Somatic
mutagenesis studies of NF-kB signaling in human T cells: evidence for an
essential role of IKKg in NF-kB activation by T-cell costimulatory signals and
HTLV-I Tax protein. Oncogene 19 1448-1456 Harhaj EW, Harhaj NS, Grant C, Mostoller K, Alefantis T, Sun SC and Wigdahl B (2005) Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kB pathway. Virology 333 145-158 Harhaj NS, Janic B, Ramos JC, Harrington Jr WJ and Harhaj EW (2007) Deregulated expression of CD40 ligand in HTLV-I infection: distinct mechanisms of downregulation in HTLV-I-transformed cell lines and ATL patients. Virology in press Harhaj NS, Sun S-C and Harhaj EW (2007) Activation of NF-kB by the human T cell leukemia virus type I (HTLV-I) Tax oncoprotein is associated with ubiquitin-dependent relocalization of IKK. Journal of Biological Chemistry 282 4185-4192 Haridas V,
Arntzen CJ and Gutterman JU (2001) Avicins, a family of triterpenoid saponons
from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kB by
inhibiting both its nuclear localization and ability to bind DNA. Proceedings
of the National Academy of Sciences USA 98 11557-11562 Hardias V, Kim SO, Nishimura G, Hausladen A, Stamler JS and Gutterman JU (2005) Avicinylation (thioesterification): A protein modification that can regulate the response to oxidative and nitrosative stress. Proceedings of the National Academy of Sciences USA 102 10088-10093 Haridas V,
Shrivastava A, Su J, Yu GL, Ni J, Liu D, Chen SF, Ni Y, Ruben SM, Gentz R and
Aggarwal BB (1999) VEGI, a new member of the TNF family activates Nuclear
Factor-kB and c-Jun N-terminal kinase and modulates cell growth. Oncogene 18
6496-6504 Harigai M, Hara M, Kawamoto M, Kawaguchi Y, Sugiura T, Tanaka M, Nakagawa M, Ichida H, Takagi K, Higami-Ohsako S, Shimada K and Kamatani N (2004) Amplification of the synovial inflammatory response through activation of mitogen-activated protein kinases and nuclear factor kB using ligation of CD40 on CD14+ synovial cells from patients with rheumatoid arthritis. Arthritis & Rheumatism 50 2167-2177 Harii N, Lewis CJ, Vasko V, McCall K, Benavides-Peralta U, Sun X, Ringel MD, Saji M, Giuliani C, Napolitano G, Goetz DJ and Kohn LD (2005) Thyrocytes express a functional Toll-like receptor 3 (TLR3): overexpression can be induced by viral infection, reversed by phenylmethimazole, and is associated with Hashimoto's autoimmune thyroiditis. Molecular Endocrinology 19 1231-1250 Harikumar KB and Aggarwal BB (2008) Resveratrol: a multitargeted agent for age-associated chronic diseases. Cell Cycle 7 in press Harimaya
A, Koizumi JI, Fujii N and Himi T (2007) Interleukin-8 induction via NF-kB,
p38 mitogen-activated protein kinase and extracellular signal-regulated
kinase1/2 pathways in human peripheral blood mononuclear cells by Alloiococcus
otitidis. Harizanova N, Georgieva T, Dunkov BC, Yoshiga T and Law JH (2005) Aedes aegypti transferrin. Gene structure, expression pattern, and regulation. Insect Molecular Biology 14 79-88 Harkonen PL and Vaananen HK (2006) Monocyte-macrophage system as a target for estrogen and selective estrogen receptor modulators. Annals of the New York Academy of Sciences 1089 218-227 Harlin H,
Hwang KW, Palucki DA, Kim O, Thompson CB, Boothby M and Alegre ML (2002)
CTLA-4 engagement regulates NF-kB activation in vivo. European Journal of
Immunology 32 2095-2104 Harlin H,
Podack E, Boothby M and Alegre ML (2002) TCR-independent CD30 signaling
selectively induces IL-13 production via a TNF receptor-associated factor/p38
mitogen-activated protein kinase-dependent mechanism. Journal of Immunology
169 2451-2459 Harling-McNabb
L, Deliyannis G, Jackson DC, Gerondakis S, Grigoriadis G and Brown LE (1999)
Mice lacking the transcription factor subunit Rel can clear an influenza
infection and have functional anti-viral cytotoxic T cells but do not develop
an optimal antibody response. International Immunology 11 1431-1439 Harnett MM (2004) CD40: a growing cytoplasmic tale. Sci STKE 237 PE25 Harnish DC,
Scicchitano MS, Adelman SJ, Lyttle CR and Karathanasis SK (2000) The role of
CBP in estrogen receptor cross-talk with nuclear factor-kB in HepG2 cells.
Endocrinology 141 3403-3411 Harper N,
Farrow SN, Kaptein A, Cohen GM and MacFarlane M (2001) Modulation of tumor
necrosis factor apoptosis-inducing ligand- induced NF-kB activation by
inhibition of apical caspases. Journal of Biological Chemistry 276 34743-34752 Harper N, Hughes MA, Farrow SN, Cohen GM and MacFarlane M (2003) Protein kinase C modulates TRAIL-induced apoptosis by targeting the apical events of death receptor signaling. Journal of Biological Chemistry 278 44338-44347 Harper N, Hughes M, MacFarlane M and Cohen GM (2003) FADD and caspase-8 are not recruited to the TNF-R1 signaling complex during TNF-induced apoptosis. Journal of Biological Chemistry 278 25534-25541 Harper R, Wu K, Chang MM, Yoneda K, Pan R, Reddy SP and Wu R (2001) Activation of nuclear factor-kappa b transcriptional activity in airway epithelial cells by thioredoxin but not by N-acetyl-cysteine and glutathione. American Journal of Respiratory Cellular and Molecular Biology 25 178-185 Harris GS, Lust RM, Deantonio JH and Katwa LC (2008) PPAR-gamma expression in animals subjected to volume overload and chronic Urotensin II administration. Peptides 29 795-800 Harris J, Oliere S, Sharma S, Sun Q, Lin R, Hiscott J and Grandvaux N (2006) Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK{epsilon}. Journal of Immunology 177 2527-2535 Harris JE, Nuttall RK, Elkington PT, Green JA, Horncastle DE, Graeber MB, Edwards DR and Friedland JS (2007) Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo. Journal of Immunology 178 1199-1207 Harris RC (2002) Cyclooxygenase-2 and the kidney: functional and pathophysiological implications. Journal of Hypertension 20 Suppl 6 S3-S9 Harousseau JL, Shaughnessy Jr J and Richardson P (2004) Multiple myeloma. Hematology Am Soc Hematol Educ Program) 237-256 Harry D,
Anand R, Holt S, Davies S, Marley R, Fernando B, Goodier D and Moore K (1999)
Increased sensitivity to endotoxemia in the bile duct-ligated cirrhotic Rat.
Hepatology 30 1198-1205 Hart BA, Lee
CH, Shukla GS, Shukla A, Osier M, Eneman JD and Chiu JF (1999)
Characterization of cadmium-induced apoptosis in rat lung epithelial cells:
evidence for the participation of oxidant stress. Toxicology 133 43-58 Hart DJ,
Speight RE, Cooper MA, Sutherland JD and Blackburn JM (1999) The salt
dependence of DNA recognition by NF-kB p50: a detailed kinetic analysis of the
effects on affinity and specificity. Nucleic Acids Research 27 1063-1069 Hart DJ,
Speight RE, Sutherland JD and Blackburn JM (2001) Analysis of the NF-kB p50
dimer interface by diversity screening. Journal of Molecular Biology 310
563-575 Hart L, Lim
S, Adcock I, Barnes PJ and Chung KF (2000) Effects of inhaled corticosteroid
therapy on expression and DNA-binding activity of nuclear factor kB in asthma.
Am J Respir Crit Care Med 161 224-231 Hart LA,
Krishnana VL, Adcock IM, Barnes PJ and Chung KF (1998) Activation and
localization of transcription factor, nculear factor-kB, in asthma. American
Journal of Respiration and Critical Care Medicine 158 1585-1582 Harte MT, Haga IR, Maloney G, Gray P, Reading PC, Bartlett NW, Smith GL, Bowie A and O'Neill LA (2003) The Poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense. Journal of Experimental Medicine 197 343-351 Hartel C, Strunk T, Bucsky P and Schultz C (2004) Effects of vitamin C on intracytoplasmic cytokine production in human whole blood monocytes and lymphocytes. Cytokine 27 101-106 Hartgring SA, Bijlsma JW, Lafeber FP and van Roon JA (2006) Interleukin-7 induced immunopathology in arthritis. Annals of the Rheumatic Disease 65 Suppl 3 iii69-iii74
Hartlage-Rubsamen
M, Lemke R and Schliebs R (1999) Interleukin-1beta, inducible nitric oxide
synthase, and nuclear factor-kB are induced in morphologically distinct
microglia after rat hippocampal lipopolysaccharide/interferon-gamma injection.
Journal of Neuroscience Research 57 388-398 Hartman MG, Lu D, Kim ML, Kociba GJ, Shukri T, Buteau J, Wang X, Frankel WL, Guttridge D, Prentki M, Grey ST, Ron D and Hai T (2004) Role for Activating Transcription Factor 3 in stress-induced {beta}-cell apoptosis. Molecular and Cellular Biology 24 5721-5732 Hartmann BL,
Geley S and Kofler R (1999) Sequence-specific transcription factors during
glucocorticoid-induced apoptosis in acute lymphoblastic leukemia cells. Wien
Klin Wochenschr 111 360-367 Hartmann G
and Krieg AM (2000) Mechanism and function of a newly identified CpG DNA motif
in human primary B cells. Journal of Immunology 164 944-953 Hartsock WJ, Cohen JD and Segal DJ (2007) Uranyl acetate as a direct inhibitor of DNA-binding proteins. Chemical Research in Toxicology 20 784-789 Hartupee J, Li X and Hamilton TA (2008) Interleukin 1a-induced NFkB activation and chemokine mRNA stabilization diverge at IRAK1. Journal of Biological Chemistry 283 15689-15693 Hartupee
J, Liu C, Novotny M, Li X and Hamilton T (2007) IL-17 enhances chemokine gene
expression through mRNA stabilization. Hartz AM, Bauer B, Block ML, Hong JS and Miller DS (2008) Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier. FASEB Journal in press Harvey DM and
Levine AJ (1991) p53 alteration is a common event in the spontaneous
immortalization of primary BALCB/c murine embryo fibroblasts. Genes &
Development 5 2375-2385 Harvey PJ,
Keightley AM, Lam YM, Cameron C, Lillicrap D (2000) A single nucleotide
polymorphism at nucleotide -1793 in the von Willebrand factor (VWF) regulatory
region is associated with plasma VWF:Ag levels. British Journal of
Haematology 109 349-353 Harvey RD and Lonial S (2007) PI3 kinase/AKT pathway as a therapeutic target in multiple myeloma. Future Oncology 3 639-647 Harwood FG,
Kasibhatla S, Petak I, Vernes R, Green DR and Houghton JA (2000) Regulation of
FasL by NF-kB and AP-1 in Fas-dependent thymineless death of human colon
carcinoma cells. Journal of Biological Chemistry 275 10023-10029 Harzenetter MD, Novotny AR, Gais P, Molina CA, Altmayr F and Holzmann B (2007) Negative regulation of TLR responses by the neuropeptide CGRP is mediated by the transcriptional repressor ICER. Journal of Immunology 179 607-615 Hasan N, Siddiqui MU, Toossi Z, Khan S, Iqbal J and Islam N (2007) Allicin-induced suppression of Mycobacterium tuberculosis 85B mRNA in human monocytes. Biochemical and Biophysical Research Communications 355 471-476 Hasan RN and Schafer AI (2008) Hemin upregulates Egr-1 expression in vascular smooth muscle cells via ROS ERK-1/2 Elk-1 and NF-kB. Circulation Research 102 42-50 Hasan UA, Dollet S and Vlach J (2004) Differential induction of gene promoter constructs by constitutively active human TLRs. Biochemical and Biophysical Research Communications 321 124-131 Hase H, Ando T, Eldeiry L, Brebene A, Peng Y, Liu L, Amano H, Davies TF, Sun L, Zaidi M and Abe E (2006) TNFa mediates the skeletal effects of thyroid-stimulating hormone. Proceedings of the National Academy of Sciences USA in press Hasebe A, Yoshimura A, Into T, Kataoka H, Tanaka S, Arakawa S, Ishikura H, Golenbock DT, Sugaya T, Tsuchida N, Kawanami M, Hara Y and Shibata KI (2004) Biological activities of Bacteroides forsythus lipoproteins and their possible pathological roles in periodontal disease. Infection & Immunity 72 1318-1325 Hasegawa A, Cheng X, Kajino K, Berezov A, Murata K, Nakayama T, Yagita H, Murali R and Greene MI (2004) Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proceedings of the National Academy of Sciences USA 101 6599-6604 Hasegawa H, Sawa H, Lewis MJ, Orba Y, Sheehy N, Yamamoto Y, Ichinohe T, Tsunetsugu-Yokota Y, Katano H, Takahashi H, Matsuda J, Sata T, Kurata T, Nagashima K and Hall WW (2006) Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I. Nature Medicine 12 466-472 Hasegawa K, Ichiyama T, Isumi H, Nakata M, Sase M, Furukawa S (2003) NF-kB activation in peripheral blood mononuclear cells in neonatal asphyxia. Clinical and Experimental Immunology 132 261-264 Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, Nunez G and Inohara N (2008) A critical role of RICK/RIP2 polyubiquitination in NOD-induced NF-kB activation. EMBO Journal 27 373-383 Hasegawa M, Imamura R, Kinoshita T, Matsumoto N, Masumoto J, Inohara N and Suda T (2005) ASC-mediated NF-kB activation leading to IL-8 production requires caspase-8 and Is inhibited by CLARP. Journal of Biological Chemistry 280 15122-15130 Hasel C, Bhanot UK, Maier R, Strater J and Moller P (2006) Parenchymal regression in chronic pancreatitis spares islets reprogrammed for expression of NFkB and IAPs [Article in German]. Verh Dtsch Ges Pathol 90 159-167 Hashem RM, Soliman HM and Shaapan SF (2008) Turmeric-based diet can delay apoptosis without modulating NF-kB in unilateral ureteral obstruction in rats. Journal of Pharmacy and Pharmacology 60 83-89
Hashemi FB,
Ghassemi M, Roebuck KA and Spear GT (1999) Activation of human
immunodeficiency virus type 1 expression by Gardnerella vaginalis. Journal of
Infectious Diseases 179 924-930 Hashikabe Y, Suzuki K, Jojima T, Uchida K and Hattori Y (2006) Aldosterone impairs vascular endothelial cell function. Journal of Cardiovascular Pharmacology 47 609-613 Hashimoto K, Ethridge RT, Saito H, Rajaraman S and Evers BM (2003) The PPARgamma ligand, 15d-PGJ2, attenuates the severity of cerulein-induced acute pancreatitis. Pancreas 27 58-66 Hashimoto K, Yamano Y and Morishima I (2008) Cloning and expression of a gene encoding gallerimycin, a cysteine-rich antifungal peptide, from eri-silkworm, Samia cynthia ricini. Comparative Biochemistry and Physiology B: Biochemistry and Molecular Biology 150 229-232 Hashimoto M, Asai Y, Tamai R, Jinno T, Umatani K and Ogawa T (2003) Chemical structure and immunobiological activity of lipid A from Prevotella intermedia ATCC 25611 lipopolysaccharide. FEBS Letters 543 98-102 Hashimoto T, Cui CY and Schlessinger D (2006) Repertoire of mouse ectodysplasin-A (EDA-A) isoforms. Gene 371 42-51
Hashimoto T,
Furuyashiki T, Sano T, Kihara K, Fukuda I, Ito W, Park P, Kanazawa K, Danno G
and Ashida H (2002) Apoptosis in the thymus after intraperitoneal injection of
rats with Trp-P-1. Environmental and Molecular Mutagenesis 40 175-183 Hashiramoto A, Sakai C, Yoshida K, Tsumiyama K, Miura Y, Shiozawa K, Nose M, Komai K and Shiozawa S (2007) Angiopoietin 1 directly induces destruction of the rheumatoid joint by cooperative, but independent, signaling via ERK/MAPK and phosphatidylinositol 3-kinase/Akt. Arthritis and Rheumatism 56 2170-2179 Hashizume K,
Hatanaka Y, Fukuda I, Sano T, Yamaguchi Y, Tani Y, Danno G, Suzuki K and
Ashida H (2002) N-acetyl-L-cysteine suppresses constitutive expression of
CD11a/LFA-1alpha protein in myeloid lineage. Leukemia Research 26 939 Haskill S,
Beg AA, Tompkins SM, Morris JS, Yurochko AD, Sampson-Johannes A, Mondal K,
Ralph P and Baldwin Jr AS(1991) Characterization of an immediate-early gene
induced in adherent monocytes that encodes IkB-like activity. Cell 65
1281-1289 Hasko G,
Mabley JG, Nemeth ZH, Pacher P, Deitch EA and Szabo C (2002) Poly(ADP-ribose)
polymerase is a regulator of chemokine production: relevance for the
pathogenesis of shock and inflammation. Molecular Medicine 8 283-289 Haslbeck KM, Bierhaus A, Erwin S, Kirchner A, Nawroth P, Schlotzer U, Neundorfer B and Heuss D (2004) Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kB activation in vasculitic neuropathy. Muscle Nerve 29 853-860 Haslbeck KM, Friess U, Schleicher ED, Bierhaus A, Nawroth PP, Kirchner A, Pauli E, Neundorfer B and Heuss D (2005) The RAGE pathway in inflammatory myopathies and limb girdle muscular dystrophy. Acta Neuropathologica (Berlin) 110 247-254 Haslbeck KM, Neundorfer B, Schlotzer-Schrehardtt U, Bierhaus A, Schleicher E, Pauli E, Haslbeck M, Hecht M, Nawroth P and Heuss D (2007) Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies? Neurology Research 29 103-110 Haslbeck KM, Schleicher E, Bierhaus A, Nawroth P, Haslbeck M, Neundorfer B and Heuss D (2005) The AGE/RAGE/NF-kB pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT). Experimental and Clinical Endocrinology of Diabetes 113 288-291 Haslinger B, Kleemann R, Toet KH and Kooistra T (2003) Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells. Kidney International 63 2065-2074 Hasnis E, Bar-Shai M, Burbea Z and Reznick AZ (2007) Cigarette smoke-induced NF-kB activation in human lymphocytes: the effect of low and high exposure to gas phase of cigarette smoke. Journal of Physiological Pharmacology 58 263-274 Hasnis E, Bar-Shai M, Burbea Z and Reznick AZ (2007) Mechanisms underlying cigarette smoke-induced NF-kB activation in human lymphocytes: the role of reactive nitrogen species. Journal of Physiological Pharmacology 58 S275-S287 Hass R, Brach
M, Gunji H, Kharbanda S and Kufe D (1992) Inhibition of EGR-1 and NF-kB
gene expression by dexamethasone during phorbol ester-induced human monocytic
differentiation. Biochemical Pharmacology 44 1569-1576 Hassa PO, Buerki C, Lombardi C, Imhof R and Hottiger MO (2003) Transcriptional coactivation of NF-kB-dependent gene expression by p300 is regulated by PARP-1. Journal of Biological Chemistry 2788 45145-45153 Hassa PO, Covic M, Bedform MT and Hottiger MO (2008) Protein arginine methyltransferase 1 coactivates NF-kB-dependent gene expression synergistically with CARM1 and PARP1. Journal of Molecular Biology 377 668-678 Hassa PO, Haenni SS, Buerki C, Meier NI, Lane WS, Owen H, Gersbach M, Imhof R and Hottiger MO (2005) Acetylation of PARP-1 by p300/CBP regulates coactivation of NF-kB-dependent transcription. Journal of Biological Chemistry 280 40450-40464 Hassa PO and
Hottiger MO (1999) A role of poly (ADP-ribose) polymerase in NF-kB
transcriptional activation. Biological Chemistry 380 953-959 Hassa PO and Hottiger MO (2002) The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-kB in inflammatory disorders. Cellular and Molecular Life Sciences 59 1534-1553 Hassa PO,
Covic M, Hasan S, Imhof R and Hottiger MO (2001) The enzymatic and DNA binding
activity of PARP-1 are not required for NF-kB coactivator function. Journal of
Biological Chemistry 276 45588-45597 Hassan F, Islam S, Koide N, Mu MM, Ito H, Mori I, Yoshida T and Yokochi T (2004) Role of p38 mitogen-activated protein kinase (MAPK) for vacuole formation in lipopolysaccharide (LPS)-stimulated macrophages. Microbiolgoy and Immunology 48 807-815 Hassan F, Islam S, Tumurkhuu G, Naiki Y, Koide N, Mori I, Yoshida T and Yokochi T (2006) Intracellular expression of toll-like receptor 4 in neuroblastoma cells and their unresponsiveness to lipopolysaccharide. BMC Cancer 6 281 Hassan M, Selimovic D, Ghozlan H and Abdel-Kader O (2006) Induction of high-molecular-weight (HMW) tumor necrosis factor(TNF) alpha by hepatitis C virus (HCV) non-structural protein 3 (NS3) in liver cells is AP-1 and NF-kB-dependent activation. Cellular Signaling 19 310-311 Hassan SB, Lovborg H, Lindhagen E, Karlsson MO and Larsson R (2006) CHS 828 kills tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. Anticancer Research 26 4431-4436 Hasselgren PO (2007) Ubiquitination, phosphorylation, and acetylation-triple threat in muscle wasting. Journal of Cellular Physiology 213 679-689 Hasselgren PO, Menconi MJ, Fareed MU, Yang H, Wei W and Evenson A (2005) Novel aspects on the regulation of muscle wasting in sepsis. Internatioanl Journal of Biochemistry and Cell Biology 37 2156-2168 Hassoun HT, Fischer UM, Attuwaybi BO, Moore FA, Safi HJ, Allen SJ and Cox CS (2003) Regional hypothermia reduces mucosal NF-kB and PMN priming via gut lymph during canine mesenteric Ischemia/Reperfusion(1,2). Journal of Surgical Research 115 121-126
Hassoun HT,
Kozar RA, Kone BC, Safi HJ and Moore FA (2002) Intraischemic hypothermia
differentially modulates oxidative stress proteins during mesenteric
ischemia/reperfusion. Surgery 132 369-376 Hassoun HT,
Zou L, Moore FA, Kozar RA, Weisbrodt NW and Kone BC (2002)
Alpha-melanocyte-stimulating hormone protects against mesenteric
ischemia-reperfusion injury. American Journal of Physiology: Gastrointestinal Liver Physiology 282
G1059-G1068 Hastak K, Gupta S, Ahmad N, Agarwal MK, Agarwal ML, Mukhtar H (2003) Role of p53 and NF-kB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. Oncogene 22 4851-4859 Hata K, Andoh
A, Shimada M, Fujino S, Bamba S, Araki Y, Okuno T, Fujiyama Y and Bamba T
(2002) IL-17 stimulates inflammatory responses via NF-kB and MAP kinase
pathways in human colonic myofibroblasts. American Journal of Physiology: Gastrointestinal
Liver
Physiology 282 G1035-G1044 Hatada EN, Do RK, Orlofsky A, Liou HC, Prystowsky M, MacLennan IC, Caamano J and Chen-Kiang S (2003) NF-kB1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kB2 p100 to p52 in quiescent mature B cells. Journal of Immunology 171 761-768 Hatada EN,
Krappmann D and Scheidereit C (2000) NF-kB and the innate immune response.
Current Opinion in Immunology 12 52-58 Hatada EN,
Naumann M and Scheidereit C (1993) Common structural constituents confer IkB
activity to NF-kB p105 and IkB/MAD-3. EMBO Journal 12 2781-2788 Hatada EN,
Nieters A, Wulczyn FG, Maumann M, Meyer R, Nucifora G, McKeithan TW and
Scheidereit C (1992) The ankyrin repeat domains of the NF-kB precursor p105
and the protooncogene bcl-3 act as specific inhibitors of NF-kB DNA binding.
Proceedings of the National Academy of Sciences USA 89 2489-2493 Hatake K, Mishima Y and Terui Y (2004) Proteasome inhibitors [Article in Japanese]. Gan To Kagaku Ryoho 31 999-1002 Hatake K, Yokoyama M, Terui Y (2007) Recent progress in rituximab therapy and its resistance - how do we overcome? [Article in Japanese]. Gan To Kagaku Ryoho 34 1177-1182 Hatekeyama M and Brzozowski T (2006) Pathogenesis of Helicobacter pylori infection. Helicobacter 11 S14-S20 Hatakeyama S,
Kitagawa M, Nakayama K, Shirane M, Matsumoto M, Hattori K, Higashi H, Nakano
H, Okumura K, Onoé K, Good RA and Nakayama K-i (1999) Ubiquitin-dependent
degradation of IkBa is mediated by a ubiquitin ligase Skp1/Cul1/F-box protein
FWD1. Proceedings of the National Academy of Sciences USA 96 3859-3863 Hatano E (2007) Tumor necrosis factor signaling in hepatocyte apoptosis. Journal of Gastroenterology and Hepatology 22 S43-S44 Hatano E and
Brenner DA (2001) Akt protects mouse hepatocytes from TNF-alpha- and
Fas-mediated apoptosis through NK-kB activation. American Journal of Physiology: Gastrointestinal
Liver Physiology 281 G1357-G1368 Hatano E,
Bennett BL, Manning AM, Qian T, Lemasters JJ and Brenner DA (2001) NF-kB
stimulates inducible nitric oxide synthase to protect mouse hepatocytes from
TNF-a- and Fas-mediated apoptosis. Gastroenterology 120 1251-1262 Hatano E,
Bradham CA, Stark A, Iimuro Y, Lemasters JJ and Brenner DA (2000) The
mitochondrial permeability transition augments Fas-induced apoptosis in mouse
hepatocytes. Journal of Biological Chemistry 275 11814-11823 Hatao F, Muroi M, Hiki N, Ogawa T, Mimura Y, Kaminishi M and Tanamoto KI (2004) Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein. Journal of Leukocyte Biology 76 904-908 Hatao F, Yamamoto M, Muroi M, Kaminishi M and Tanamoto KI (2008) MyD88-induced downregulation of IRAK-4 and its structural requirements. FEMS Immunology and Medical Microbiology 53 260-264 Hatcher H, Planalp R, Cho J, Torti FM and Torti SV (2008) Curcumin: from ancient medicine to current clinical trials. Cellular and Molecular Life Sciences 65 1631-1652 Hatfield P, Merrick AE, West E, O'Donnell D, Selby P, Vile R and Melcher AA (2008) Optimization of dendritic cell loading with tumor cell lysates for cancer immunotherapy. Journal of Immunotherapy in press Hatta Y, Arima N, Machino T, Itoh T, Hashimoto S, Takeuchi J, Sawada U, Hayakawa S, Yamamoto T and Horie T (2003) Mutational analysis of IkB in hematologic malignancies. International Journal of Molecular Medicine 11 239-242 Hattori N, Machida Y and Noda K (2005) Pathogenesis of Parkinson's disease: a common pathway between alpha-synuclein and parkin and the mechanism of Lewy bodies formation [Article in Japanese}. Rinsho Shinkeigaku 45 905-907 Hattori T,
Hayashi H, Chiba T and Onozaki K (2001) Activation of two distinct
anti-proliferative pathways, apoptosis and p38 MAP kinase-dependent cell cycle
arrest, by tumor necrosis factor in human melanoma cell line A375. European
Cytokine Network 12 244-252 Hattori Y,
Akimoto K, Murakami Y, Kasai K. (1997) Pyrrolidine Dithiocarbamate inhibits
cytokine-induced VCAM-1 gene expression in rat cardiac myocytes. Molecular and
Cellular Biochemistry 177 177-181 Hattori Y,
Banba N, Gross SS and Kasai K (1999) Glycated serum albumin-induced nitric
oxide production in vascular smooth muscle cells by nuclear factor
kB-dependent transcriptional activation of inducible nitric oxide synthase.
Biochemical and Biophysyical Research Communications 259 128-132 Hattori
Y, Hattori S, AKimoto K, Nishikimi T, Suzuki K, Matsuoka H and Kasai K (2007)
Globular adiponectin activates nuclear factor-kB and activating protein-1 and
enhances angiotensin II-induced proliferation in cardiac fibroblasts. Hattori Y,
Hattori S and Kasai K (1999) Troglitazone upregulates nitric oxide synthesis
in vascular smooth muscle cells. Hypertension 33 943-948 Hattori Y,
Hattori S and Kasai K (2001) 4-hydroxynonenal prevents NO production in
vascular smooth muscle cells by inhibiting nuclear factor-kB-dependent
transcriptional activation of inducible NO synthase. Arteriosclerosis, Thrombosis
and Vascular
Biology 21 1179-1183 Hattori Y, Hattori S and Kasai K (2003) Lipopolysaccharide activates Akt in vascular smooth muscle cells resulting in induction of inducible nitric oxide synthase through nuclear factor-kB activation. European Journal of Pharmacology 481 153-158 Hattori Y, Kasai K and Gross SS (2004) NO suppresses while peroxynitrite sustains NF-kB: a paradigm to rationalize cytoprotective and cytotoxic actions attributed to NO. Cardiovascular Research 63 31-40 Hattori Y, Matsumura M and Kasai K (2003) Vascular smooth muscle cell activation by C-reactive protein. Cardiovascular Research 58 186-195
Hattori Y,
Nakanishi N and Kasai K (2002) Statin enhances cytokine-mediated induction of
nitric oxide synthesis in vascular smooth muscle cells. Cardiovascular Research 54
649-658 Hattori Y, Nakano Y, Hattori S, Tomizawa A, Inukai K and Kasai K (2008) High molecular weight adiponectin activates AMPK and suppresses cytokine-induced NF-kB activation in vascular endothelial cells. FEBS Letters in press Hattori Y, Suzuki K, Hattori S and Kasai K (2006) Metformin inhibits cytokine-induced nuclear factor kB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension 47 1183-11888 Hatzivassiliou
E and Mosialos G (2002) Cellular signaling pathways engaged by the
Epstein-Barr virus transforming protein LMP1. Frontiers in Bioscience 7 d319-d329 Hau DD, Lewis MJ, Saltibus LF, Pastushok L, Xiao W and Spyracopoulos L (2006) Structure and interactions of the ubiquitin-conjugating enzyme variant human uev1a: implications for enzymatic synthesis of polyubiquitin chains. Biochemistry 45 9866-9877 Haudek SB,
Bryant DD and Giroir BP (2001) Differential regulation of myocardial NF kB
following acute or chronic TNF-alpha exposure. Journal of Molecular and Cellular Cardiology 33 1263-1271 Haudek SB, Spencer E, Bryant DD, White DJ, Maass D, Horton JW, Chen ZJ and Giroir BP (2001) Overexpression of cardiac I-kBa prevents endotoxin-induced myocardial dysfunction. Am J Physiol Heart Circ Physiol 280 H962-H968 Hauer J, Puschner S, Ramakrishnan P, Simon U, Bongers M, Federle C and Engelmann H (2005) TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kB pathway by TRAF-binding TNFRs. Proceedings of the National Academy of Sciences USA 102 2874-2879 Hauf N and Chakraborty T (2003) Suppression of NF-kB activation and proinflammatory cytokine expression by Shiga toxin-producing Escherichia coli. Journal of Immunology 170 2074-2082
Hauf N,
Goebel W, Fiedler F and Kuhn M (1999) Listeria monocytogenese infection of
Caco-2 human epithelial cells induces activation of transcription factor
NF-kB/Rel-like DNA binding activities. FEMS Micrbiology Letters 178 117-122 Haugen F and Drevon CA (2007) Activation of nuclear factor-kB by high molecular weight and globular adiponectin. Endocrinology in press Hauser B, Kick J, Ivanyi Z, Asfar P, Ehrmann U, Muth CM, Albicini M, Wachter U, Vogt J, Bauer M, Bruckner UB, Radermacher P and Bracht H (2006) Effects of 15-deoxy-delta(12,14)-prostaglandin-J(2) during hyperdynamic porcine endotoxemia. Intensive Care Medicine 32 759-765 Haussler U, von Wichert G, Schmid RM, Keller F and Schneider G (2005) Epidermal growth factor (EGF) activates nuclear factor kB in human proximal tubule cells. American Journal of Physiology: Renal Physiology 289 F808-F815
Havard L,
Delvenne P, Frare P, Boniver J and Giannini SL (2002) Differential production
of cytokines and activation of NF-kB in HPV-transformed keratinocytes.
Virology 298 271-285 Havard L, Rahmouni S, Boniver J and Delvenne P (2005) High levels of p105 (NFKB1) and p100 (NFKB2) proteins in HPV16-transformed keratinocytes: role of E6 and E7 oncoproteins. Virology 331 357-366 Haversen L, Ohlsson BG, Hahn-Zoric M, Hanson LA and Mattsby-Baltzer I (2002) Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-kB. Cellular Immunology 220 83-95 Hawkins BJ, Solt L, Chowdhury I, Kazi AS, Abid MR, Aird WC, May MJ, Foskett JK and Madesh M (20070 GPCR Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/leukocyte adherence. Molecular and Cellular Biology in press Hawn T,
Ozinsky A, Underhill D, Buckner F, Akira S and Aderem A (2002) Leishmania
major activates IL-1alpha expression in macrophages through a MyD88-dependent
pathway. Microbes and Infection 4 763 Hay DC, Beers C, Cameron V, Thomson L, Flitney FW and Hay RT (2003) Activation of NF-kB nuclear transcription factor by flow in human endothelial cells. Biochimica et Biophysica Acta 1642 33-44 Hay DC, Kemp
GD, Dargemont C and Hay RT (2001) Interaction between hnRNPA1 and IkBa is
required for maximal activation of NF-kB-dependent transcription. Molecular
and Cellular Biology 21 3482-3490 Hay RT (1993)
Control of Nuclear Factor-kB DNA-binding activity by inhibitory proteins
containing ankyrin repeats. Biochemical Society Transactions 21 926-930 Hay RT and
Nicholson J (1993) DNA binding alters the protease susceptibility of the p50
subunit of NF-kB. Nucleic Acids Research 21 4592-4598 Hay RT,
Vuillard L, Desterro JM and Rodriguez MS (1999) Control of NF-kB
transcriptional activation by signal induced proteolysis of IkBa.
Philos Trans R Soc Lond B Biol Sci 354 1601-1609 Hayakawa
H, Hayakawa M, Kume A and Tominaga SI (2007) Soluble ST2 blocks IL-33
signaling in allergic airway inflammation. Hayakawa K, Hiramatsu N, Okamura M, Yao J, Paton AW, Paton JC and Kitamura M (2007) Blunted activation of NF-kB and NF-kappaB-dependent gene expression by geranylgeranylacetone: Involvement of unfolded protein response. Biochemical and Biophysical Research Communications in press Hayakawa K, Meng Y, Hiramatsu N, Kasai A, Yamauchi K, Yao J and Kitamura M (2006) Priming of glomerular mesangial cells by activated macrophages causes blunted responses to proinflammatory stimuli. Journal of Immunology 176 2529-2537 Hayakawa K, Meng Y, Hiramatsu N, Kasai A, Yamauchi K, Yao J and Kitamura M (2006) Spontaneous activation of the NF-kB signaling pathway in isolated normal glomeruli. American Journal of Physiology: Renal Physiology in press Hayakawa M, Miyashita H, Sakamoto I, Kitagawa M, Tanaka H, Yasuda H, Karin M and Kikugawa K (2003) Evidence that reactive oxygen species do not mediate NF-kB activation. EMBO Journal 22 3356-3366 Hayashi A, Chiba T, Hayashi H, Sasayama S, Ishiguro T and Onazaki K (2006) Synthesis of glycosylated human tumor necrosis factor alpha coupled with N-acetylneuraminic acid. Cancer Immunol Immunother Hayashi H,
Ichihara M, Iwashita T, Murakami H, Shimono Y, Kawai K, Kurokawa K, Murakumo
Y, Imai T, Funahashi H, Nakao A and Takahashi M (2000) Characterization of
intercellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor. Oncogene 19 4469-4475 Hayashi H, Nagaki M, Imose M, Osawa Y, Kimura K, Takai S, Imao M, Naiki T, Kato T and Moriwaki H (2005) Normal liver regeneration and liver cell apoptosis after partial hepatectomy in tumor necrosis factor-alpha-deficient mice. Liver International 25 162-170 Hayashi K and Altman A (2006) Filamin A is required for T cell activation mediated by protein kinase C-theta. Journal of Immunology 177 1721-1728 Hayashi K and Alman A (2007) Protein kinase C theta (PKCtheta): A key player in T cell life and death. Pharmacological Research in press Hayashi K, Pu H, Tian J, Andras IE, Lee YW, Hennig B and Toborek M (2005) HIV-Tat protein induces P-glycoprotein expression in brain microvascular endothelial cells. Journal of Neurochemistry 93 1231-1241 Hayashi K,
Takahata H, Kitagawa N, Kitange G, Kaminogo M and Shibata S (2001)
N-acetylcysteine inhibited nuclear factor-kB expression and the intimal
hyperplasia in rat carotid arterial injury. Neurology Research 23 731-738 Hayashi M, Shimba S and Tezuki M (2007) Characterization of the molecular clock in mouse peritoneal macrophages. Biological and Pharmaceutical Bulletin 30 621-626 Hayashi R, Wada H, Ito K and Adcock IM (2004) Effects of glucocorticoids on gene transcription. European Journal of Pharmacology 500 51-62 Hayashi S, Hatashita M, Hayashi A, Matsumoto H, Shioura H adn Kitai R (2008) Thermosensitization by parthenolide in human lung adenocarcinoma A549 cells and p53- and hsp72-independent apoptosis induction via the nuclear factor-kB signal pathway. International Journal of Molecular Medicine 21 585-592 Hayashi S and Hogg JC (2007) Adenovirus infections and lung disease. Current Opininion in Pharmacology in press Hayashi S,
Yamamoto M, Ueno Y, Ikeda K, Ohshima K, Soma G and Fukushima T (2001)
Expression of nuclear factor-kappa B, tumor necrosis factor receptor type 1,
and c-Myc in human astrocytomas. Neurol Med Chir (Tokyo) 41 187-195 Hayashi T and
Faustman D (1999) NOD mice are defective in proteasome production and
activation of NF-kB. Molecular and Cellular Biology 19 8646-8659 Hayashi T and
Faustman D (2000) Essential role of human leukocyte antigen-encoded proteasome
subunits in NF-kB activation and prevention of tumor necrosis
factor-alpha-induced apoptosis. Journal of Biological Chemistry 275 5238-5247 Hayashi T and
Faustman DL (2001) Selected contribution: Association of gender-related LMP2
inactivation with autoimmune pathogenesis. Journal of Applied Physiology 91
2804-2815 Hayashi T and Faustman DL (2003) Role of defective apoptosis in type 1 diabetes and other autoimmune diseases. Recent Progress in Hormone Reseach 58 131-153 Hayashi T, Ishida Y, Kimura A, Iwakura Y, Mukaida N and Kondo T (2007) IFN-g protects cerulein-induced acute pancreatitis by repressing NF-kB activation. Journal of Immunology 178 7385-7394
Hayashi T,
Kaneda T, Toyama Y, Kumegawa M and Hakeda Y (2002) Regulation of receptor
activator of NF-kB ligand-induced osteoclastogenesis by endogenous
interferon-{beta} and suppressors of cytokine signaling (SOCS): The possible
counteracting role of SOCSs in IFN-{beta} inhibited osteoclast formation. Journal
of Biological Chemistry 277 27880-27886 Hayashi T, Mo JH, Gong X, Rossetto C, Jang A, Beck L, Elliott GI, Kufareva I, Abagyan R, Broide DH, Lee J and Raz E (2007) 3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis. Proceedings of the National Academy of Sciences USA in press Hayashi T,
Sekine T and Okamoto T (1993) Identification of a new serine kinase that
activates NFkB by direct phosphorylation. Journal of Biological Chemistry 268
26790-26795 Hayashi T,
Ueno Y and Okamoto T (1993) Oxidoreductive regulation of nuclear factor kB.
Involvement of a cellular reducing catalyst thioredoxin. Journal of Biological
Chemistry 268 11380-11388 Hayashi T, Yamashita C, Matsumoto C, Kwak CJ, Fuji K, Hirata T, Miyamura M, Mori T, Ukimura A, Okada Y, Matsumura T and Kitaura Y (2008) Role of gp91phox-containing NADPH oxidase in left ventricular remodeling induced by intermittent hypoxic stress. American Journal of Physiology: Heart and Circulatory Physiology in press Haycock JW,
Wagner M, Morandini R, Ghanem G, Rennie IG and Mac Neil S (1999)
Alpha-melanocyte-stimulating hormone inhibits NF-kB activation in human
melanocytes and melanoma cells. Journal of Investigative Dermatology 113 560-566 Haycock JW,
Wagner M, Morandini R, Ghanem G, Rennie IG and MacNeil S (1999) alpha-MSH
immunomodulation acts via rel/NF-kB in cutaneous and ocular melanocytes and in
melanoma cells. Annals of the New York Academy of Sciences 885 396-399 Hayden MS and Ghosh S (2004) Signaling to NF-kB. Genes & Development 18 2195-2224 Hayden MS and Ghosh S (2008) Shared principles in NF-kB signaling. Cell 132 344-362 Hayden MS, West AP and Ghosh S (2006) SnapShot: NF-kB signaling pathways. Cell 127 1286-1287 Hayden MS, West AP and Ghosh S (2006) NF-kB and the immune response. Oncogene 25 6758-6780 Hayes AL, Smith C, Foxwell BM and Brennan FM (1999) CD45-induced tumor necrosis factor alpha production in monocytes is phosphatidylinositol 3-kinase-dependent and nuclear factor-kB-independent. Journal of Biological Chemistry 274 33455-33461 Hayes JD, Flanagan JU and Jowsey IR (2005) Glutathione transferases. Annual Review of Pharmacology and Toxicology 45 51-88 Hayes JD, Kelleher MO and Eggleston IM (2008) The cancer chemopreventive actions of phytochemicals derived from glucosinolates. European Journal of Nutrition 47 S73-S88 Haynes L, Eaton SM, Burns EM, Rincon M and Swain SL (2004) Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo. Journal of Immunology 172 5194-5199 Hayot F and Jayaprakash C (2005) NF-kB oscillations and cell-to-cell variability. Journal of Theoretical Biology 240 583-591 Hazan U,
Thomas D, Alcami J, Bachelerie F, Israël N, Yssel H, Virelizier JL and
Arenzana-Seisdedos F (1990) Stimulation of a human T-cell clone with anti-CD3
or tumor necrosis factor induces NF-kB translocation but not human
immunodeficiency virus 1 enhancer-dependent transcription. Proceedings of the
National Academy of Sciences USA 87 7861-7865 Hazeki K, Kinoshita S, Matsumura T, Niorikawa K, Kubo H and Hazeki O (2006) Opposite effects of wortmannin and LY294002 on TLR- mediated nitric oxide production: negative regulation of NF-kB by phosphoinositide 3-kinase. Molecular Pharmacology 69 1717-1724 Hazeki
K, Nigorikawa K and Hazeki O (2007) Role of phosphoinositide 3-kinase in
innate immunity. Hazlett LD, Li Q, Liu J, McClellan S, Du W and Barrett RP (2007) NKT cells are critical to initiate an inflammatory response after Pseudomonas aeruginosa ocular infection in susceptible mice. Journal of Immunology 179 1138-1146 He AW and
Cory JG (1998) Effect of ionizing radiation on wild-type and mutant mouse
leukemia L1210 cells. Oncology Research 10 455-464 He AW and
Cory JG (1999) p53-independent anisomycin induced G1 arrest and apoptosis in
L1210 cell lines. Anticancer Research 19 421-428 He B, Chadburn A, Jou E, Schattner EJ, Knowles DM and Cerutti A (2004) Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL. Journal of Immunology 172 3268-3279 He B and Weber GF (2004) Synergistic activation of the CMV promoter by NF-kB P50 and PKG. Biochemical and Biophysical Research Communications 321 13-20 He B, Qiao X and Cerutti A (2004) CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10. Journal of Immunology 173 4479-4491 He BF and Weber G (2003) Phosphorylation of NF-kB proteins by cyclic GMP-dependent kinase. European Journal of Biochemistry 270 2174-2185 He D, Natarajan V, Stern R, Gorshkova IA, Solway J, Spannhake EW and Zhao Y (2008) Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclooxygenase-2 expression and prostaglandin E2 release via C/EBPbeta in human bronchial epithelial cells. Biochemical Journal in press He GH, Helbing CC, Wagner MJ, Sensen CW and Riabowol K (2005) Phylogenetic analysis of the ING family of PHD finger proteins. Molecular Biology and Evolution 22 104-116 He H and Kogut MH (2003) CpG-ODN-induced nitric oxide production is mediated through clathrin-dependent endocytosis, endosomal maturation, and activation of PKC, MEK1/2 and p38 MAPK, and NF-kB pathways in avian macrophage cells (HD11). Cell Signal 15 911-917 He HB, Dai DZ and Dai Y (2006) CPU0213, a novel endothelin receptor antagonist, ameliorates septic renal lesion by suppressing ET system and NF-kB in rats. Acta Pharmacologica Sinica 27 1213-1221 He
HJ, PIres R, Zhu TN, Zhou A, Gaigalas AK, Zou S and Wang L (2007) Fluorescence
resonance energy transfer-based method for detection of DNA binding activities
of nuclear factor kB. He J, Lu KZ and Tao GC (2008) Propofol ameliorates rat liver ischemia-reperfusion injury possibly by inhibiting nuclear factor-kappaB expression [Article in Chinese]. Nan Fang Yi Ke Da Xue Xue Bao 28 1064-1066 He J, Zhou F, Shao K, Hang J, Wang H, Rayburn E, Xiao ZX, Lee SW, Xue Q, Feng XL, Shi SS, Zhang CY and Zhang S (2007) Overexpression of Pin1 in non-small cell lung cancer (NSCLC) and its correlation with lymph node metastases. Lung Cancer in press He JK, Yu SD, Zhu HJ, Wu JC and Qin ZH (2007) Triptolide inhibits NF-kB activation and reduces injury of donor lung induced by ischemia/reperfusion. Acta Pharmacologica Sinica 28 1919-1923 He JQ, Oganesyan G, Saha SK, Zarnegar B and Cheng G (2007) TRAF3 and its biological function. Advances in Experimental Medicine and Biology 597 48-59 He JQ, Saha SK, Kang JR, Zarnegar B and Cheng G (2007) Specificity of TRAF3 in its negative regulation of the noncanoncial NF-kB pathway. Journal of Biological Chemistry 282 3688-3694 He JQ, Zarnegar B, Oganesyan G, Saha SK, Yamazaki S, Doyle SE, Dempsey PW and Cheng G (2006) Rescue of TRAF3-null mice by p100 NF-kB deficiency. Journal of Experimental Medicine 203 2413-2418 He JX, Zhao SY and Jiang ZF (2005) Demonstration of a mechanism of anti-inflammatory effect of erythromycin on allergic airway inflammation in rat [Article in Chinese]. Zhonghua Er Ke Za Zhi 43 196-198 He KL and
Ting AT (2002) A20 inhibits tumor necrosis factor (TNF) alpha-induced
apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1
complex in Jurkat T cells. Molecular and Cellular Biology 22
6034-6045 He KL and Ting AT (2003) Essential role for IKKg/NEMO in TCR-induced IL-2 expression in Jurkat T cells. European Journal of Immunology 33 1917-1924 He L, Grammer AC, Wu X and Lipsky PE (2004) TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-kB activation. Journal of Biological Chemistry 279 55855-55865 He L, Kim BY, Kim KA, Kwon O, Kim SO, Bae EY, Lee MS, Kim MS, Jung M, Moon A, Bae K and Ahn HS (2007) NF-kappaB inhibition enhances caspase-3 degradation of Akt1 and apoptosis in response to camptothecin. Cellular Signaling in press He L, Wu X, Siegel R and Lipsky PE (2006) TRAF6 regulates cell fate decisions by inducing caspase 8-dependent apoptosis and the activation of NF-kB. Journal of Biological Chemistry 281 11235-11249 He M, He X, Xie Q, Chen F and He S (2005) Angiotensin II induces the expression of tissue factor and its mechanism in human monocytes. Thrombosis Research 117 579-590 He ML, Li A, Xu CS, Wang SL, Zhang MJ, Gu H, Yang YQ and Tao HH (2007) Mechanisms of antiprostate cancer by gum mastic: NF-kB signal as target. Acta Pharmacologica Sinica 28 446-452 He MX, He XF, Xie QZ, Chen FP and He SL (2003) Effect of angiotensin II on tissue factor expression in human peripheral blood monocytes and its mechanisms [Article in Chinese]. Zhonghua Xue Ye Xue Za Zhi 24 470-473 He N, Yakiyama M, Fujii H, Banno Y and Yamamoto K (2003) Genomic structure and expression analysis of the gene encoding a silkworm basic Kunitz-type chymotrypsin inhibitor. Biochimica et Biophysica Acta 1628 71-77 He P, Zhong Z, Lindholm K, Berning L, Lee W, Lemere C, Staufenbiel M, Li R and Shen Y (2006) Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice. Journal of Cell Biology 178 829-841 He R, Leeson A, Andonov A, Li Y, Bastien N, Cao J, Osiowy C, Dobie F, Cutts T, Ballantine M and Li X (2003) Activation of AP-1 signal transduction pathway by SARS coronavirus nucleocapsid protein. Biochemical and Biophysical Research Communications 311 870-876 He R, Sang H and Ye RD (2002) Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. Blood 101 1572-1581 He R, Shepard LW, Chen J, Pan ZK and Ye RD (2006) Serum amyloid A is an endogenous ligand that differentially induces IL-12 and IL-23. Journal of Immunology 177 4072-4079 He T, He Z, Mo L and Liang N (2005) Study on the effect and its mechanisms of 5F from Pteri semipinnata L. on the cell cycle of highly metastatic ovarian carcinoma HO-8910PM cells [Article in Chinese]. Zhong Yao Cai 28 672-676 He TP, Mo LE and Liang NC (2005) Inhibitory effect of cantharidin on invasion and metastasis of highly metastatic ovarian carcinoma cell line HO-8910PM [Article in Chinese]. Ai Zheng 24 443-447 He W, Liu Q, Wang L, Chen W, Li N and Cao X (2007) TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance. Molecular Immunology 44 2850-2859 He X, Han B, Mura M, Xia S, Wang S, Ma T, Liu M and Liu Z (2007) Angiotensin-converting enzyme inhibitor captopril prevents oleic acid-induced severe acute lung injury in rats. Shock in press He YT, Liu DW, Ding LY, Li Q and Xiao YH (2004) Therapeutic effects and molecular mechanisms of anti-fibrosis herbs and selenium on rats with hepatic fibrosis. World Journal of Gastroenterology 10 703-706
He Z, Xin B,
Yang X, Chan C and Cao L (2000) Nuclear factor-kB activation is involved in
LMP1-mediated transformation and tumorigenesis of rat-1 fibroblasts. Cancer
Research 60 1845-1848 He ZM and Chen ZC (2003) Construction and function analysis of a CTAR-2 region mutant of the Epstein-Barr Virus-encoded latent membrane protein-1 [Article in Chinese]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35 261-265 He ZY, Zou ZX, Yu L, Zhong NS, Ran PX and Zhong XN (2005) Effects of erythromycin on hydrogen peroxide-induced interleukin-8 synthesis and regulation of glutathione in human bronchial epithelial cells [Article in Chinese]. Zhonghua Yi Xue Za Zhi 85 976-980 Healy AM, Izmailova E, Fitzgerald M, Walker R, Hattersley M, Silva M, Siebert E, Terkelsen J, Picarella D, Pickard MD, Leclair B, Chandra S and Jaffee B (2006) PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis. Journal of Immunology 177 1886-1893
Healy JI,
Dolmetsch RE, Lewis RS and Goodnow CC (1998) Quantitative and qualitative
control of antigen receptor signalling in tolerant B lymphocytes. Novartis
Foundation Symposium 215 137-144 Heath WR
(2001) Motility is more important than [correction of that] stealth. Trends in
Immunology 22 353 Hebeis BJ, Vigorito E and Turner M (2004) The p110delta subunit of phosphoinositide 3-kinase is required for the lipopolysaccharide response of mouse B cells. Biochemical Society Transactions 32 789-791 Hecht G,
Marrero JA, Danilkovich A, Matkowskyj KA, Savkovic SD, Koutsouris A and Benya
RV (1999) Pathogenic Escherichia coli increase Cl- secretion from intestinal
epithelia by upregulating galanin-1 receptor expression. Journal of Clinical
Investigation 104 253-262 Hecht I, Hershkoviz R, Shivtiel S, Lapidot T, Cohen IR, Lider O and Cahalon L (2004) Heparin-disaccharide affects T cells: inhibition of NF-kB activation, cell migration, and modulation of intracellular signaling. Journal of Leukocyte Biology 75 1139-1146 Hecht M, von Metzler I, Sack K, Kaiser M and Sezer O (2007) The in vitro immunomodulatory activity of a synthetic brassinosteroid analogue would account for the improvement of herpetic stromal keratitis in mice. Experimental Cell Research in press Hecht SS, Huang C, Stoner GD, Li J, Kenney PM, Sturla SJ and Camella SG (2006) Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NFkB and AP-1 activity. Carcinogenesis 27 1617-1626 Heck S, Bender K, Kullmann M, Gottlicher M, Herrlich P and Cato ACB (1997) IkBa-independent downregulation of NF-kB activity by glucocorticoid receptor. EMBO Journal 16 4698-4707 Heck S,
Lezoualc'h F, Engert S and Behl C (1999) Insulin-like growth factor-1-mediated
neuroprotection against oxidative stress is associated with activation of
nuclear factor kB. Journal of Biological Chemistry 274 9828-9835 Heckscher ES, Fetter RD, Marek KW, Albin SD and Davis GW (2007) NF-kB, IkB, and IRAK control glutamate receptor density at the Drosophila NMJ. Neuron 55 859-873 Heckmann A, Waltzinger C, Jolicoeur P, Dreano M, Kosco-Vilbois MH and Sagot Y (2004) IKK2 inhibitor alleviates kidney and wasting diseases in a murine model of human AIDS. American Journal of Pathology 164 1253-1262 Heckman CA, Cao T, Somsouk L, Duan H, Mehew JW, Zhang CY and Boxer LM (2003) Critical elements of the immunoglobulin heavy chain gene enhancers for deregulated expression of bcl-2. Cancer Research 63 6666-6673 Heckman CA,
Mehew JW and Boxer LM (2002) NF-kB activates Bcl-2 expression in t(14;18)
lymphoma cells. Oncogene 21 3898-3908 Heckman CA,
Mehew JW and Boxer LM (2002) NF-kB activates Bcl-2 expression in t(14;18)
lymphoma cells. Oncogene 21 3898-3908 Hedengren-Olcott M, Olcott MC, Mooney DT, Ekengren S, Geller BL and Taylor BJ (2004) Differential activation of the NF-kB-like factors relish and Dif in Drosophila melanogaster by fungi and gram-positive bacteria. Journal of Biological Chemistry 279 21121-21127 Hedtjarn M, Mallard C and Hagberg H (2004) Inflammatory gene profiling in the developing mouse brain after hypoxia-ischemia. Journal of Cerebreal Blood Flow Metabolism 24 1333-1351 Heermeier K,
Leicht W, Palmetshofer A, Ullrich M, Wanner C and Galle J (2001) Oxidized LDL
suppresses NF-kB and overcomes protection from apoptosis in activated
endothelial cells. Journal of the American Society of Nephrology 12 456-463 Heeschen C,
Weis M, Aicher A, Dimmeler S and Cooke JP (2002) A novel angiogenic pathway
mediated by non-neuronal nicotinic acetylcholine receptors. Journal of
Clinical Investigation 110 527-536 Heese K, Inoue N and Sawada T (2006) NF-kB regulates B-cell-derived nerve growth factor expression. Cellular and Molecular Immunology 3 63-66 Hegazy DM,
O'Reilly DA, Yang BM, Hodgkinson AD, Millward BA and Demaine AG (2001) NFkB
polymorphisms and susceptibility to type 1 diabetes. Genes & Immunity 2
304-308 Hegde S, Pahne J and Smola-Hess S (2004) Novel immunosuppressive properties of interleukin-6 in dendritic cells: inhibition of NF-kB binding activity and CCR7 expression. FASEB Journal 18 1439-1441 Hehlgans T, Muller P, Stopfer P and Mannel DN (2003) Activation of the lymphotoxin-beta receptor induces NFkB-dependent interleukin-6 and MIP-2 secretion in mouse fibrosarcoma cells. European Cytokine Network 14 103-107 Hehner SP, Breitkreutz R, Shubinsky G, Unsoeld H, Schulze-Osthoff K, Schmitz ML and Droge W (2000) Enhancement of T-cell receptor signaling by a mild oxidative shift in the intracellular thiol pool. Journal of Immunology 165 4319-4328
Hehner SP,
Heinrich M, Borks PM, Vogt M, Ratter F, Lehmann V, Schulze-Osthoff K, Droge W
and Schmitz ML (1998) Sesquiterpene lactones specifically inhibit activation
of NF-kB by preventing the degradation of IkB-a and IkB-b. Journal of
Biological Chemistry 273 1288-1297 Hehner SP,
Hofmann TG, Droge W and Schmitz ML (1999) The antiinflammatory sesquiterpene
lactone parthenolide inhibits NF-kB by targeting the IkB kinase complex.
Journal of Immunology 163 5617-5623 Hehner SP,
Hofmann TG, Ratter F, Droge W and Schmitz ML (1999) Inhibition of tyrosine
phosphatases antagonizes CD95-mediated apoptosis. European Journal of
Biochemistry 264 132-139 Hehner SP, Hofmann TG, Ratter F, Dumont A, Droge W and Schmitz ML (1998) Tumor Necrosis Factor-alpha-induced cell killing and activation of transcription factor NF-kB are uncoupled in L929 cells. Journal of Biological Chemistry 273 18117-18121 Hehner SP,
Hofmann TG, Ushmorov A, Dienz O, Wing-Lan Leung I, Lassam N, Scheidereit C,
Droge W and Schmitz ML (2000) Mixed-lineage kinase 3 delivers CD3/CD28-derived
signals into the IkB kinase complex. Molecular and Cellular Biology 20
2556-2568 Hehner SP,
Li-Weber M, Giaisi M, Droge W, Krammer PH and Schmitz ML (2000) Vav synergizes
with protein kinase C theta to mediate IL-4 gene expression in response to
CD28 costimulation in T cells. Journal of Immunology 164 3829-3836 Heidemann J, Ruther C, Kebschull M, Domschke W, Bruewer M, Koch S, Kucharzik T and Maaser C (2007) Expression of IL-12 related molecules in human intestinal microvascular endothelial cells is regulated by TLR3. American Journal of Physiology: Gastrointestinal Liver Physiology 36 351-359 Heider U, von Metzler I, Kaiser M, Rosche M, Sterz J, Rotzer S, Rademacher J, Jakob C, Fleissner C, Kuckelkorn U, Kloetzel PM and Sezer O (2007) Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma. European Journal of Haematology in press Heidrich FM, Zhang K, Estrada M, Huang Y, Giordano FJ and Ehrlich BE (2008) Chromogranin B regulates calcium signaling, nuclear factor kB activity, and brain natriuretic peptide production in cardiomyocytes. Circulation Research in press Heijink IH, Kies PM, van Ooosterhaout AJ, Postma DS, Kauffman HF and Vellenga E (2007) Der p, IL-4 and TGF-beta cooperatively induce EGFR-dependent TARC expression in airway epithelium. American Journal of Respiratory Cell and Molecular Biology 36 351-359 Heikkila HM, Latti S, Leskinen MJ, Hakala JK, Kovanen PT and Lindstedt KA (2007) Activated mast cells induce endothelial cell apoptosis by a combined action of chymase and tumor necrosis factor-a. Arteriosclerosis, Thrombosis, and Vascular Biology in press Heilker R,
Freuler F, Pulfer R, Di Padova F and Eder J (1999) All three IkB isoforms and
most Rel family members are stably associated with the IkB kinase 1/2 complex.
European Journal of Biochemistry 259 253-261 Heim MH,
Moradpour D and Blum HE (1999) Expression of hepatitis C virus proteins
inhibits signal transduction through the Jak-STAT pathway. Journal of Virology
73 8469-8475 Heimberg H, Heremans Y, Jobin C, Leemans R, Cardozo AK, Darville M and Eizirik DL (2001) Inhibition of cytokine-induced NF-kB activation by adenovirus- mediated expression of a NF-kB super-repressor prevents beta-cell apoptosis. Diabetes 50 2219-2224 Heimesaat MM, Fischer A, Jahn HK, Niebergall J, Freudenberg M, Blaut M Lisenfeld O, Schumann RR, Gobel UB and Bereswill S (2007) Exacerbation of murine ileitis by Toll-like receptor 4 meditated sensing of lipopolysaccharide from commensal Escherichia coli. Gut in press Hein GE (2006) Glycation end products in osteoporosis - is there a pathophysiologic importance? Clinica Chimica Acta 371 32-36 Hein I, Campbell EI, Woodhead M, Hedley PE, Young V, Morris WL, Ramsay L, Stockhaus J, Lyon GD, Newton AC and Birch PR (2004) Characterisation of early transcriptional changes involving multiple signalling pathways in the Mla13 barley interaction with powdery mildew (Blumeria graminis f. sp. hordei). Planta 218 803-813 Heine G, Anton K, Henz BM and Worm M
(2002) Heine H, El-Samalouti VT, Notzel C, Pfeiffer A, Lentschat A, Kusumoto S, Schmitz G, Hamann L and Ulmer AJ (2003) CD55/decay accelerating factor is part of the lipopolysaccharide-induced receptor complex. European Journal of Immunology 33 1399-1408 Heinemann S, Biesinger B, Fleckenstein B and Albrecht JC (2006) NF-kB signaling is induced by the oncoprotein tio through direct interaction with TRAF6. Journal of Biological Chemistry 281 8565-8572 Heinrich M (2003) Ethnobotany and natural products: the search for new molecules, new treatments of old diseases or a better understanding of indigenous cultures? Current Topics in Medicinal Chemistry 3 141-154
Heinrich M,
Bork PM, Schmitz ML, Rimpler H, Frei B and Sticher O (2001) Pheophorbide A
from Solanum diflorum interferes with NF-kB activation. Planta Med 67
156-157 Heinrich M and Bremner P (2006) Ethnobotany and ethnopharmacy - their role for anti-cancer drug development. Current Drug Targets 7 239-245 Heinrichs S and Deppert W (2003) Apoptosis or growth arrest: modulation of the cellular response to p53 by proliferative signals. Oncogene 22 555-571 Heiss E and Gerhauser C (2005) Time-dependent modulation of thioredoxin reductase activity might contribute to sulforaphane-mediated inhibition of NF-kB binding to DNA. Antioxidants and Redox Signaling 7 1601-1611 Heiss E,
Herhaus C, Klimo K, Bartsch H and Gerhauser C (2001) Nuclear factor kB is a
molecular target for sulforaphane-mediated anti-inflammatory mechanisms.
Journal of Biological Chemistry 276 32008-32015 Heissmeyer V and Rao A (2008) Itching to end NF-kB. Nature Immunology 9 227-229 Heissmeyer V, Krappmann D, Hatada E., Scheidereit C (2000) Shared pathways of IkB kinase-induced SCFbTrCP –mediated ubiquitination and degradation for the NF-kB precursor p105 and IkBa. Molecular and Cellular Biology 21 1024-1035 Heissmeyer V,
Krappmann D, Wulczyn FG and Scheidereit C (1999) NF-kB p105 is a target of IkB
kinases and controls signal induction of Bcl-3-p50 complexes. EMBO Journal 18
4766-4778 Helbig G, Christopherson KW 2nd, Bhat-Nakshatri P, Kumar S, Kishimoto H, Miller KD, Broxmeyer HE and Nakshatri H (2003) NF-kB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. Journal of Biological Chemistry 278 21631-21638
Held TK,
Weihua X, Yuan L, Kalvakolanu DV and Cross AS (1999) Gamma interferon augments
macrophage activation by lipopolysaccharide by two distinct mechanisms, at the
signal transduction level and via an autocrine mechanism involving tumor
necrosis factor alpha and interleukin-1. Infection and Immunity 67 206-212 Helenius M, Hänninen
M, Lehtinen SK and Salminen A (1996) Aging-induced up-regulation of nuclear
binding activities of oxidative stress responsive NF-?B transcription factor
in mouse cardiac muscle. Journal of Molecular Cell Cardiology 28 487-498 Helenius M,
Makelainen L and Salminen A (1999) Attenuation of NF-kB signaling response to
UVB light during cellular senescence. Experimental Cell Research 248 194-202 Helin E,
Vainionpaa R, Hyypia T, Julkunen I and Matikainen S (2001) Measles virus
activates NF-kB and STAT transcription factors and production of IFN-a/beta and
IL-6 in the human lung epithelial cell line A549. Virology 290 1-10 Hellerbrand C, Bumes E, Bataille F, Dietmaier W, Massoumi R and Bosserhoff AK (2006) Reduced expression of CYLD in human colon and hepatocellular carcinomas. Carcinogenesis in press Hellerbrand
C, Jobin C, Iimuro Y, Licato L, Sartor RB and Brenner DA (1998) Inhibition of
NFkB in activated rat hepatic stellate cells by proteasome inhibitors and an
IkB super-repressor. Hepatology 27 1285-1295 Hellerbrand
C, Jobin C, Licato LL, Sartor RB and Brenner DA (1998) Cytokines induce NF-kB
in inactivated but not in quiescent rat hepatic stellate cells. American
Journal of Physiology 271 G269-G278 Hellermann G, Kong X, Gunnarsdottir J, San Juan H, Singam R, Behera S, Zhang W, Lockey RF and Mohapatra SS (2004) Mechanism of bronchoprotective effects of a novel natriuretic hormone peptide. Journal of Allergy Clinical Immunology 113 79-85 Hellerud BC, Stenvik J, Espevik T, Lambris JD, Mollnes TE and Brandtzaeg P (2008) The stages of meningococcal sepsis simulated in vitro with emphasis on complement and Toll-like receptor activation. Infection and Immunity in press Hellin A-C,
Calmant P, Gielen J, Bours V and Merville M-P (1998) Nuclear
Factor-kB-dependent regulation of p53 gene expression induced by daunomycin
genotoxic drug. Oncogene 16 1187-1195 Hellmuth M,
Wetzler C, Nold M, Chang JH, Frank S, Pfeilschifter J and Muhl H (2001)
Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth
factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate.
Carcinogenesis 23 1273-1279 Hellweg CE and Baumstark-Khan C (2007) Detection of UV-induced activation of NF-kB in a recombinant human cell line by means of Enhanced Green Fluorescent Protein (EGFP). Radiation and Environmental Biophysics in press Helmer KS,
Chang L, Cui Y and Mercer DW (2002) Induction of NF-kB, IkB-a, and iNOS in rat
gastric mucosa during endotoxemia. Journal of Surgical Research 104 46-52 Helmer KS, West SD and Mercer DW (2003) Ketamine attenuates endotoxin-induced pro-inflammatory cytokine expression. Journal of Surgical Research 114 288 Hellweg CE, Baumstark-Khan C and Horneck G (2003) Generation of stably transfected Mammalian cell lines as fluorescent screening assay for NF-kB activation-dependent gene expression. Journal of Biomolecular Screening 8 511-521 Helmer KS, West SD, Vilela R, Chang L, Cui Y, Kone BC and Mercer DW (2004) Lipopolysaccharide-induced changes in rat gastric H/K-ATPase expression. Annals of Surgery 239 501-509 Hémar A,
Barrand P, Ferrer M, Cornet V, Buttin G and Dautry-Varsat A (1991) Activity of
the kB enhancer of the interleukin-2 receptor a chain in somatic cell hybrids
is accompanied by the nuclear localization of NF-kB. The New Biologist 3
1097-1105 Hémar A,
Cereghini S, Cornet V, Blank V, Israël A, Greene WC and Dautry-Versat A
(1991) kB binding proteins are constitutively expressed in an IL-2 autocrine
human T cell line. Journal of Immunology 146 2409-2416 Hemavathy K,
Meng X and Ip YT (1997) Differential regulation of gastrulation and
neuroectodermal gene expression by Snail in the Drosophila embryo. Development
124 3683-3691 Hemby SE (2004) Morphine-induced alterations in gene expression of calbindin immunopositive neurons in nucleus accumbens shell and core. Neuroscience 126 689-703 Hemish J, Nakaya N, Mittal V and Enikolopov G (2003) Nitric oxide activates diverse signaling pathways to regulate gene expression. Journal of Biological Chemistry 278 42321-42329 Hemmi H, Takeuchi O, Sato S, Yamamoto M, Kaisho T, Sanjo H, Kawai T, Hoshino K, Takeda K and Akira S (2004) The roles of two IkB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. Journal of Experimental Medicine 199 1641-1650 Henderson BC and Tyagi SC (2006) Alterations in T cell signal transduction by M. leprae antigens is associated with downregulation of second messengers PKC, calcium, calcineurin, MAPK and various transcription factors in leprosy patients. Molecular Immunology in press Henderson WR
Jr, Chi EY, Teo JL, Nguyen C and Kahn MA (2002) Small molecule inhibitor of
redox-regulated NF-kB and Activator Protein-1 transcription blocks allergic
airway inflammation in a mouse asthma model. Journal of Immunology 169
5294-5299 Heneka MT, Gavrilyuk V, Landreth GE, O'Banion MK, Weinberg G and Feinstein DL (2003) Noradrenergic depletion increases inflammatory responses in brain: effects on IkB and HSP70 expression. Journal of Neurochemistry 85 387-398 Heneka MT,
Sharp A, Klockgether T, Gavrilyuk V and Feinstein DL (2000) The heat shock
response inhibits NF-kB activation, nitric oxide synthase type 2 expression,
and macrophage/microglial activation in brain. Journal of Cerebral Blood Flow
and Metabolism 20
800-811 Heneka MT,
Sharp A, Murphy P, Lyons JA, Dumitrescu L and Feinstein DL (2001) The heat
shock response reduces myelin oligodendrocyte glycoprotein- induced
experimental autoimmune encephalomyelitis in mice. Journal of Neurochemistry
77 568-579 Henke N, Schmidt-Ullrich R, Dechend R, Park JK, Qadri F, Wellner M, Obst M, Gross V, Dietz R, Luft FC, Schediereit C adn Muller DN (2007) Vascular endothelial cell-specific NF-kB suppression attenuates hypertension-induced renal damage. Circulation Research in press Henkel T,
Machleidt T, Alkalay I, Krönke M, Ben-Neriah Y and Baeuerle PA (1993) Rapid
proteolysis of IkB-a in response to phorbol ester, cytokines and
lipopolysaccharide is a necessary step in the activation of NF-kB. Nature 365
182-185 Henkel T,
Zabel U, van Zee K, Muller JM, Fanning E and Baeuerle PA (1992) Intramolecular
masking of the nuclear location signal and dimerization domain in the
precursor for the p50 NF-kB subunit. Cell 68 1121-1133 Henkler F, Baumann B, Fotin-Mleczek M, Weingartner M, Schwenzer R, Peters N, Graness A, Wirth T, Scheurich P, Schmid JA and Wajant H (2003) Caspase-mediated cleavage converts TRAF1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-kB activation. Journal of Biological Chemistry 278 29216-29230 Henn IH, Bouman L, Schlehe JS, Schlierf A, Schramm JE, Wegener E, Nakaso K, Clumsee C, Berninger B, Krappmann D, Tatzelt J and Winklhofer KF (2007) Parkin mediates neuroprotection through activation of IkB kinase/nuclear factor-kB signaling. Journal of Neuroscience 27 1868-1878
Henneke P and
Golenbock DT (2001) TIRAP: how Toll receptors fraternize. Nature Immunology 2
828-830 Henneke P, Morath S, Uematsu S, Weichert S, Pfitzenmaier M, Takeuchi O, Muller A, Poyart C, Akira S, Berner R, Teti G, Geyer A, Hartung T, Trieu-Cuot P, Kasper DL and Golenbock DT (2005) Role of lipoteichoic acid in the phagocyte response to group B streptococcus. Journal of Immunology 175 6449-6455
Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V,
Akira S, Kasper DL and Golenbock DT (2002) Cellular activation, phagocytosis,
and bactericidal activity against group B streptococcus involve parallel
myeloid differentiation factor 88-dependent and independent signaling
pathways. Journal of Immunology 169 3970-3977 Henness S, Johnson CK, Ge Q, Armour CL, Hughes JM and Ammit AJ (2004) IL-17A augments TNF-alpha-induced IL-6 expression in airway smooth muscle by enhancing mRNA stability. Journal of Allergy and Clinical Immunology 114 958-964 Henness S, van Thoor E, Ge Q, Armour CL, Hughes JM and Ammitt AJ (2006) IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM. American Journal of Physiology: Lung Cell and Molecular Physiology 290 L1283-L1290 Hennig B, Lei W, Arzuaga X, Ghosh DD, Saraswathi V and Toborek M (2006) Linoleic acid induces proinflammatory events in vascular endothelial cells via activation of PI3K/Akt and ERK1/2 signaling. Journal of Nutritional Biochemistry in press Hennig B,
Meerarani P, Ramadass P, Watkins BA and Toborek M (2000) Fatty acid-mediated
activation of vascular endothelial cells. Metabolism 49 1006-1013 Hennig B,
Meerarani P, Toborek M and McClain CJ (1999) Antioxidant-like properties of
zinc in activated endothelial cells. J Am Coll Nutr 18 152-158 Hennig B,
Slim R, Toborek M and Robertson LW (1999) Linoleic acid amplifies
polychlorinated biphenyl-mediated dysfunction of endothelial cells. J Biochem
Mol Toxicol 13 83-91 Hennighausen
L and Furth PA (1990) NF-kB and HIV. Nature 343 218-219 Henning LN, Azad AK, Parsa KV, Crowther JE, Tridanpani S and Schlesinger LS (2008) Pulmonary surfactant protein A regulates TLR expression and activity in human macrophages. Journal of Immunology 180 7847-7858 Henriksen PA, Hitt M, Xing Z, Wang J, Haslett C, Riemersma RA, Webb DJ, Kotelevtsev YV and Sallenave JM (2004) Adenoviral gene delivery of elafin and secretory leukocyte protease inhibitor attenuates NF-kB-dependent inflammatory responses of human endothelial cells and macrophages to atherogenic stimuli. Journal of Immunology 172 4535-4544 Henriquet C, Gougat C, Combes A, Lazennec G and Mathieu M (20070 Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells. Lung Cancer in press Henriquez NV,
Floettmann E, Salmon M, Rowe M and Rickinson AB (1999) Differential responses
to CD40 ligation among Burkitt lymphoma lines that are uniformly responsive to
Epstein-Barr virus latent membrane protein 1. Journal of Immunology 162
3298-3307 Henson ES, Gibson EM, Villanueva J, Bristow NA, Haney N and Gibson SB (2003) Increased expression of Mcl-1 is responsible for the blockage of TRAIL-induced apoptosis mediated by EGF/ErbB1 signaling pathway. J Cell Biochem 89 1177-1192 Hentze H, Latta M, Kunstle G, Dhakshinamoorthy S, Ng PY, Porter AG and Wendel A (2004) Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis. Hepatology 39 1311-1320 Heo JS, Lee MY and Han HJ (20070 Sonic Hedgehog stimulates mouse embryonic stem cell proliferation by cooperation Of Ca2+/protein kinase C and EGF receptor as well as Gli1 activation. Stem Cells in press Heo KS, Lee SJ, Ko JH, Lim K and Lim KT (2004) Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-kB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells. Toxicology In Vitro 18 755-763 Heo KS and Lim KT (2005) Glycoprotein isolated from Solanum nigrum L. modulates the apoptotic-related signals in 12-O-tetradecanoylphorbol 13-acetate-stimulated MCF-7 cells. J Med Food 8 69-77 Heo SK, Yun HJ, Park WH and Park SD (2008) NADPH oxidase activation is required for migration by LIGHT in human monocytes. Biochemical and Biophysical Research Communcations in press Heppner C,
Bilimoria KY, Agarwal SK, Kester M, Whitty LJ, Guru SC, Chandrasekharappa SC,
Collins FS, Spiegel AM, Marx SJ and Burns AL (2001) The tumor suppressor protein
menin interacts with NF-kB proteins and inhibits NF-kB-mediated
transactivation. Oncogene 20 4917-4925 Heppner C,
Bilimoria KY, Agarwal SK, Kester M, Whitty LJ, Guru SC, Chandrasekharappa SC,
Collins FS, Spiegel AM, Marx SJ and Burns AL (2001) The tumor suppressor
protein menin interacts with NF-kB proteins and inhibits NF-kB-mediated
transactivation. Oncogene 20 4917-4925 Herbein G, Varin A and Fulop T (2006) NF-kB, AP-1, zinc-deficiency and aging. Biogerontology 7 409-419 Herbein G, Varin A, Larbi A, Fortin C, Mahlknecht U, Fulop T and Aggarwal BB (2008) Nef and TNFa are coplayers that favor HIV-1 replication in monocytic cells and primary macrophages. Current HIV Research 6 117-129 Herfarth H,
Brand K, Rath HC, Rogler G, Scholmerich J and Falk W (2000) Nuclear factor-kB
activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced
colitis in mice is suppressed by gliotoxin. Clinical and Experimental Immunology 120 59-65 Herman RK, Molestina RE, Sinai AP and Howe DK (2007) The apicomplexan pathogen Neospora caninum inhibits host cell apoptosis in the absence of discernible NF-kB activation. Infection and Immunity in press Hermani A, De Servi B, Medunjanin S, Tessier PA and Mayer D (2006) S100A8 and S100A9 activate MAP kinase and NF-kB signaling pathways and trigger translocation of RAGE in human prostate cancer cells. Experimental Cell Research 332 184-197 Hermann P and Dobbelaere DA (2006) Theileria-induced constitutive IKK activation is independent of functional Hsp90. FEBS Letters in press Herrmann F, Trowsdale J, Huber C and Seliger B (2003) Cloning and functional analyses of the mouse tapasin promoter. Immunogenetics 55 379-388 Hermann-Kleiter N, Thuille N,
Pfeifhofer C, Gruber T, Schafer M, Zitt C, Hatzelmann A, Schudt C, Leitges M
and Baier G (2006) PKC{theta} and PKA are antagonistic partners in the NF-AT
transactivation pathway of primary mouse CD3+ T lymphocytes. Hermisson M and Weller M (2003) NF-kB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells. Cell Death & Differentiation 10 1078-1089 Hermoso MA and Cidlowski JA (2003) Putting the brake on inflammatory responses: the role of glucocorticoids. IUBMB Life 55 497-504 Hermoso MA, Matsuguchi T, Smoak K and Cidlowski JA (2004) Glucocorticoids and tumor necrosis factor alpha cooperatively regulate toll-like receptor 2 gene expression. Molecular and Cellular Biology 24 4743-4756 Hernandez A, Burger M, Blomberg BB, Ross WA, Gaynor JJ, Lindner I, Cirocco R, Mathew JM, Carreno M, Jim Y, Lee KP, Esquenazi V and Miller J (2007) Inhibition of NF-kB during human dendritic cell differentiation generates anergy and regulatory T-cell activity for one but not two human leukocyte antigen DR mismatches. Human Immunology 68 715-729 Hernandez A, Lindner I, Blomberg BB, Hussini S, Burger M, Mathew JM, Carreno M, Garcia-Morales R, Fuller L, Jin Y, Rosen A, Lee KP, Miller J and Esquenazi V (2003) Suppression of allogeneic T cell proliferation through blocking of NF-KB in the differentiation process of human dendritic cells. Human Immunology 64 S128 Hernandez A, Lopez-Lluch G, Bernal JA, Navas P and Pinto-Toro JA (2008) Dicoumarol down-regulates human PTTG1/Securin mRNA expression through inhibition of Hsp90. Molecular Cancer Therapeutics 7 474-482 Hernandez M,
Bayon Y, Sanchez Crespo M and Nieto ML (1999) Signaling mechanisms involved in
the activation of arachidonic acid metabolism in human astrocytoma cells by
tumor necrosis factor-a: phosphorylation of cytosolic phospholipase A2 and
transactivation of cyclooxygenase-2. Journal of Neurochemistry 73 1641-1649 Hernandez M,
de Arriba AF, Merlos M, Fuentes L, Crespo MS and Nieto ML (2001) Effect of
4-trifluoromethyl derivatives of salicylate on nuclear factor kB-dependent
transcription in human astrocytoma cells. British Journal of Pharmacology 132
547-555 Hernandez-Gutierrez S, Garcia-Pelaez I, Zentalla-Dehesa A, Ramos-Kuri M, Hernancez-Franco P, Hernandez-Sanchez F and Rojas E (2006) NF-kB signaling blockade by Bay 11-7085 during early cardiac morphogenesis induces alterations of the outflow tract in chicken heart. Apoptosis inp ress Hernandez Gutierrez S and Rojas del Castillo E (2005) Role of the transcription factor NF-kB in the cardiac cell [Article in Spanish]. Archives de Cardiologia de Mexico 75 363-370 Hernandez-Presa
MA, Bustos C, Ortego M, Tunon J, Ortega L and Egido J (1998) ACE inhibitor
quinapril reduces the arterial expression of NF-kB-dependent proinflammatory
factors but not of collagen I in a rabbit model of atherosclerosis. American
Journal of Pathology 153 1825-1837 Hernandez-Presa
MA, Gomez-Guerrero C and Egido J (1999) In situ non-radioactive detection of
nuclear factors in paraffin sections by Southwestern histochemistry. Kidney
International 55 209-214 Hernandez-Presa MA, Ortego M, Tunon J, Martin-Ventura JL, Mas S, Blanco-Colio LM, Aparicio C, Ortega L, Gomez-Gerique J, Vivanco F and Egido J (2003) Simvastatin reduces NF-kB activity in peripheral mononuclear and in plaque cells of rabbit atheroma more markedly than lipid lowering diet. Cardiovascular Research 57 168-177 Hernandez-Romano J, Carlos-Rivera FJ, Salgado H, Lamadrid-Figueroa H, Valverde-Garuno V, Rodriguez MH and Martinez-Barnetche J (2008) Immunity related genes in dipterans share common enrichment of AT-rich motifs in their 5 prime regulatory regions that are potentially involved in nucleosome formation. BMC Genomics 9 326 Hernandez-Vargas H, Rodriguez-Pinilla SM, Julian-Tendero M, Sanchez-Rovira P, Cuevas C, Anton A, Rios MJ, Palacios J and Moreno-Bueno G (2006) Gene expression profiling of breast cancer cells in response to gemcitabine: NF-kB pathway activation as a potential mechanism of resistance. Breast Cancer Research and Treatment in press Hernandez-Vargas P, Ortiz-Munoz G, Lopez-Franco O, Suzuki Y, Gallego-Delgado J, Sanjuan G, Lazaro A, Lopez-Parra V, Ortega L, Egido J and Gomez-Guerrero C (2006) Fcgamma receptor deficiency confers protection against atherosclerosis in apolipoprotein E knockout mice. Circulation Research in press
Herndon TM,
Juang YT, Solomou EE, Rothwell SW, Gourley MF and Tsokos GC (2002) Direct
transfer of p65 into T lymphocytes from systemic lupus erythematosus patients
leads to increased levels of interleukin-2 promoter activity. Clinical
Immunology 103 145-153 Herndon TM, Pirone DM, Tsokos GC and Chen CS (2005) T cell-to-T cell clustering enhances NF-kB activity by a PI3K signal mediated by Cbl-b and Rho. Biochemical and Biophysical Research Communications 332 1133-1139
Herr I and
Debatin KM (2001) Cellular stress response and apoptosis in cancer therapy.
Blood 98 2603-2614 Herrera F, Martin V, Rodriguez-Blanco J, Garcia-Santos G, Antolin I and Rodriguez C (2005) Intracellular redox state regulation by parthenolide. Biochemical and Biophysical Research Communications 332 321-325 Herrero JA,
Mathew P and Paya CV (1995) LMP-1 activates NF-kB by targeting the inhibitory
molecular IkBa. Journal of Virology 69 2168-2174 Herrero-Beaumont G, Marcos ME, Sanchez-Pernaute O, Granados R, Ortega L, Montell E, Verges J, Egido J and Largo R (2008) Effect of chondroitin sulphate in a rabbit model of atherosclerosis aggravated by chronic arthritis. British Journal of Pharmacology 154 843-851 Herrero-Fresneda I, Torras J, Franquesa M, Viadal A, Cruzado JM, Lloberas N, Fillat C and Grinyo JM (2006) HGF gene therapy attenuates renal allograft scarring by preventing the profibrotic inflammatory-induced mechanisms. Kidney International in press Herrin BR and Justement LB (2006) Expressiono f the adaptor protein hematopoietic Src homology 2 is up-regulated in response to stimuli that promote survival and differentiation of B cells. Journal of Immunology 176 4163-4172 Herring AC
and Kaminski NE (1999) Cannabinol-mediated inhibition of nuclear factor-kB,
cAMP response element-binding protein, and interleukin-2 secretion by
activated thymocytes. J Pharmacol Exp Ther 291 1156-1163 Herrlich P,
Bender K, Knebel A, Bohmer FD, Gross S, Blattner C, Rahmsdorf HJ and
Gottlicher M (1999) Radiation-induced signal transduction. Mechanisms and
consequences. C R Acad Sci III 322 121-125 Herrmann JL,
Beham AW, Sarkiss M, Chiao PJ, Rands MT, Bruckheimer EM, Brisbay S and
McDonnell TJ (1997) Bcl-2 suppresses apoptosis resulting from disruption of
the NF-kB survival pathway. Experimental Cell Research 237 101-109 Herrmann JL,
Briones F, Jr., Brisbay S, Logothetis CJ and McDonnell TJ (1998) Prostate
carcinoma cell death resulting from inhibition of proteasome activity is
independent of functional Bcl-2 and p53. Oncogene 17 2889-2899 Herrmann
O, Baumann B, de Lorenzi R, Muhammad S, Zhang W, Kleesiek J, Malfertheiner M,
Kohrmann M, Potrovita I, Maegele I, Beyer C, Bruke JR, Hasan MT, Bujard H,
Wirth T, Pasparakis M and Schwaninger M (2005) IKK mediates ischemia-induced
neuronal death. Nature Medicine 11 1322-1329 Hershkovitz O, Zilka A, Bar-Ilan A, Abutbul S, Davidson A, Mazzon M, Kummerer BM, Monsoengo A, Jacobs M and Porgador A (2008) Dengue replicon expressing the non-structural proteins suffices to enhance membrane expression of HLA class I and inhibit lysis by human NK cells. Journal of Virology in press Herscovitch M, Comb W, Ennis T, Coleman K, Yong S, Armstead B, Kalaaitzidis D, Chandani S and Gilmore TD (2007) Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347. Biochemical and Biophysical Research Communications 367 103-108 Hershfield MS (2005) New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunodeficiency associated with adenosine deaminase deficiency. European Journal of Immunology 35 25-30 Hershko DD,
Robb BW, Hungness ES, Luo G, Guo X and Hasselgren PO (2002) Arsenite inhibits
interleukin-6 production in human intestinal epithelial cells by
down-regulating nuclear factor-kB activity. Clinical Science (London) 103
381-390 Hershko DD,
Robb BW, Luo G and Hasselgren PO (2002) Multiple transcription factors
regulating the IL-6 gene are activated by cAMP in cultured Caco-2 cells. American Journal
of Physiology: Regulatroy, Integrative & Comparative Physiology 283 R1140-R1148 Hershko DD, Robb BW, Wray CJ, Luo GJ and Hasselgren PO (2004) Superinduction of IL-6 by cycloheximide is associated with mRNA stabilization and sustained activation of p38 map kinase and NF-kB in cultured caco-2 cells. Journal of Cellular Biochemistry 91 951-961 Hertelendy F,
Molnar M and Romero R (2002) Interferon gamma antagonizes
interleukin-1beta-induced cyclooxygenase-2 expression and prostaglandin E(2)
production in human myometrial cells. J Soc Gynecol Investig 9 215-219 Herter J and
Fuchs S (2002) Recognition of substrate and Skp1 by the Homologue of Slimb
(HOS) ubiquitin ligase receptor D role of the F-box. Medical Science Monitor 8
BR283-BR288 Hertig C,
Coupar BEH, Gould AR and Boyle DB (1997) Field and vaccine strains of fowlpox
virus carry integrated sequences from the avian retrovirus, reticuloendotheliosis virus. Virology 235 367-376 Hertlein E and Byrd JC (2008) CLL and activated NF-kB: living partnership. Blood 111 4427 Hertlein E, Wang J, Ladner KJ, Bakkar N and Guttridge DC (2005) RelA/p65 regulation of IkBb. Molecular and Cellular Biology 25 4956-4968 Herve R, Schmitz T, Evain-Brion D, Cabrol D, Leroy MJ and Mehats C (2008) The PDE4 inhibitor rolipram prevents NF-kB binding activity and proinflammatory cytokine release in human chorionic cells. Journal of Immunology 181 2196-2202 Herwamana S, Albhazal S, Lin TT, Clement M, Jenkins C, Guzman ML, Jordan CT, Neelakantan S, Crooks PA, Burnett AK, Pratt G, Fegan C, Rowntree C, Brennaan P and Pepper C (2008) The NF-{kappa}B subunit, Rel A, is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukaemia and represents a promising therapeutic target. Blood in press Herzog NK and
Bose Jr HR (1986) Expression of the oncogene of avian reticuloendotheliosis
virus in Escherichia coli and identification of the transforming protein in
reticuloendotheliosis virus T-transformed cells. Proceedings of the National
Academy of Sciences USA 83 812-816 Herzog NK,
Bargmann WJ and Bose Jr HR (1986) Oncogene expression in reticuloendotheliosis
virus-transformed lymphoid cell lines and avian tissues. Journal of Virology
57 371-375 Herzog NK,
Bargmann WJ, Moore BE, Rice NR and Bose Jr HR (1984) The expression of the
oncogene of avian reticuloendotheliosis virus in transformed cell lines and
avian tissues. In,Genes and Cancer, edited by JM Bishop, JD Rowley and M
Greaves. Alan R Liss pp 329-337 Hess A, Wijayanti N, Pathe Neuschafer-Rube A, Katz N, Kietzmann T and Immenschuh S (2003) Phorbol ester-dependent activation of peroxiredoxin I gene expression via a protein kinase C, Ras, p38 mitogen-activated protein kinase signaling pathway. Journal of Biological Chemistry 278 45419-45434 Hess DC,
Howard E, Cheng C, Carroll J, Hill WD and Hsu CY (2000) Hypertonic mannitol
loading of NF-kB transcription factor decoys in human brain microvascular
endothelial cells blocks upregulation of ICAM-1. Stroke 31 1179-1186 Hess KL, Donahue AC, Ng KL, Moore TI, Oak J and Fruman DA (2004) The p85a isoform of phosphoinositide 3-kinase is essential for a subset of B cell receptor-initiated signaling responses. European Journal of Immunology 34 2968-2976 Hess S,
Gottfried E, Smola H, Grunwald U, Schuchmann M and Engelmann H (1998) CD40
induces resistance to TNF-mediated apoptosis in a fibroblast cell line.
European Journal of Immunology 28 3594-3604 Hesse AK, Dorger M, Kupatt C and Krombach F (2004) Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury. Respiration Research 5 11 Hettman T,
DiDonato J, Karin M and Leiden JM (1999) An essential role for nuclear factor
kB in promoting double positive thymocyte apoptosis. Journal of Experimental
Medicine 189 145-158 Hettmann T and Leiden JM (2000) NF-kB is required for the positive selection of CD8+ thymocytes. Journal of Immunology 165 5004-5010 Hettmann T, Opferman JT, Leiden JM and Ashton-Rickardt PG (2003) A critical role for NF-kB transcription factors in the development of CD8(+) memory-phenotype T cells. Immunology Letters 85 297-300 Hettne KM, de Mos M, de Bruijn AG, Weeber M, Boyer S, van Mulligen EM, Cases M, Mestres J and van der Lei J (2007) Applied information retrieval and multidisciplinary research: new mechanistic hypotheses in Complex Regional Pain Syndrome. Journal of Biomedical Discovery and Collaboration in press Hetzel M, Walcher D, Grub M, Bach H, Hombach V and Marx N (2003) Inhibition of MMP-9 expression by PPARgamma activators in human bronchial epithelial cells. Thorax 58 778-783 Heusch M, Lin
L, Geleziunas R and Greene WC (1999) The generation of nfkb2 p52:
mechanism and efficiency. Oncogene 18 6201-6208 Heussler VT,
Fernandez PC, Jr JM, Botteron C and Dobbelaere DA (1999) N-acetylcysteine
blocks apoptosis induced by N-alpha-tosyl-L-phenylalanine chloromethyl ketone
in transformed T-cells. Cell Death & Differentiation 6 342-350 Heussler VT,
Kuenzi P, Fraga F, Schwab RA, Hemmings BA and Dobbelaere DA (2001) The Akt/PKB
pathway is constitutively activated in Theileria- transformed leucocytes, but
does not directly control constitutive NF-kB activation. Cellular Microbiology 3
537-550 Heussler VT,
Machado Jr J, Fernandez PC, Botteron C, Chen CG, Pearse MJ and Dobbelaere DA
(1999) The intracellular parasite Theileria parva protects infected T cells
from apoptosis. Proceedings of the National Academy of Sciences USA 96
7312-7317 Heussler VT,
Rottenberg S, Schwab R, Kuenzi P, Fernandez PC, McKellar S, Shiels B, Chen ZJ,
Orth K, Wallach D and Dobbelaere DA (2002) Hijacking of host cell IKK
signalosomes by the transforming parasite Theileria. Science 298 1033-1036 Hevia H, Varela-Rey M, Corrales FJ, Berasain C, Martinez-Chantar ML, Latasa MU, Lu SC, Mato JM, Garcia-Trevijano ER and Avila MA (2004) 5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes. Hepatology 39 1088-1098 Hewamana S, Alghazal S, Lin TT, Clement M, Jenkins C, Guzman ML, Jordan CT, Neelakantan S, Crooks PA, Burnett Ak, Pratt G, Fegan C, Rowntree C, Brennan P and Pepper C (2008) The NF-kB subunit, RelA, is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukaemia and represents a promising therapeutic target. Blood in press Hewetson A and Chilton BS (2008) Progesterone-dependent DNA looping between RUSH/SMARCA3 and Egr-1 medicates repression by c-Rel. Molecular Endocrinology in press Hewitt M, Creel A, Estell K, Davis IC and Schwiebert LM (2008) Acute exercise decreases airway inflammation, but not responsiveness, in an allergic asthma model. American Journal of Respiratory Cell and Molecular Biology in press Hewson QD, Lovat PE, Corazzari M, Catterall JB and Redfern CP (2005) The NF-kB pathway mediates fenretinide-induced apoptosis in SH-SY5Y neuroblastoma cells. Apoptosis 10 493-498 Heyninck K and Beyaert R (2005) A20 inhibits NF-kB activation by dual ubiquitin-editing functions. Trends in Biochemical Sciences 30 1-4 Heyninck K,
De Valck D, Vanden Berghe W, Van Criekinge W, Contreras R, Fiers W, Haegeman G
and Beyaert R (1999) The zinc finger protein A20 inhibits TNF-induced
NF-kB-dependent gene expression by interfering with an RIP- or
TRAF2-mediated transactivation signal and directly binds to a novel
NF-kB-inhibiting protein ABIN. Journal of Cell Biology 145 1471-1482 Heyninck K, Kreike MM and Beyaert R (2003) Structure-function analysis of the A20-binding inhibitor of NF-kB activation, ABIN-1. FEBS Letters 536 135-140 Heyninck K, Van Huffel S, Kreike M and Beyaert R (2004) Yeast two-hybrid screening for proteins interacting with the anti-apoptotic protein a20. Methods in Molecular Biology 282 223-242 Heyninck K, Wullaert A and Beyaert R (2003) Nuclear factor-kB plays a central role in tumour necrosis factor-mediated liver disease. Biochemical Pharmacology 66 1409-1415 Hezi-Yamit A, Wong PW, Bien-Ly N, Komuves LG, Prasad KS, Phillips DR and Sinha U (2005) Synergistic induction of tissue factor by coagulation factor Xa and TNF: Evidence for involvement of negative regulatory signaling cascades. Proceedings of the National Academy of Sciences USA 102 12077-12082
Hiasa G,
Hamada M, Ikeda S and Hiwada K (2001) Ischemic preconditioning and
lipopolysaccharide attenuate nuclear factor-kappaB activation and gene
expression of inflammatory cytokines in the ischemia-reperfused rat heart. Jpn
Circ J 65 984-990 Hibner U,
Benhamou L, Haury M, Cazenave P-A and Sarthou P (1994) Signalling of
programmed cell death induction in WEHI-231 B lymphoma cells. European Journal
of Immunology 24 1993-1999 Hickenbottom
SL, Grotta JC, Strong R, Denner LA and Aronowski J (1999) Nuclear Factor-kB
and cell death after experimental intracerebral hemorrhage in rats. Stroke 30
2472-2477; discussion 2477-2478 Hickman SP, Yang J, Thomas RM, Wells AD and Turka LA (2006) Defective activation of protein kinase C and Ras-ERK pathways limits IL-2 production and proliferation by CD4+CD25+ regulatory T cells. Journal of Immunology 177 2186-2194 Hickey FB, Brereton CF and Mills KH (2008) Adenylate cycalse toxin from Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells. Journal of Leukocyte Biology in press Hida A,
Kawakami A, Nakashima T, Yamasaki S, Sakai H, Urayama S, Ida H, Nakamura H,
Migita K, Kawabe Y and Eguchi K (2000) Nuclear Factor-kB and caspases
co-operatively regulate the activation and apoptosis of human macrophages.
Immunology 99 553-560 Hidaka F, Matsuo S, Muta T, Takeshige K, Mizukami T and Nunoi H (2006) A missense mutation of the Toll-like receptor 3 gene in a patient with influenza-associated encephalopathy. Clinical Immunology 119 188-194 Hidaka H,
Ishiko T, Furuhashi T, Kamohara H, Suzuki S, Miyazaki M, Ikeda O, Mita S,
Setoguchi T and Ogawa M (2002) Curcumin inhibits interleukin 8 production and
enhances interleukin 8 receptor expression on the cell surface. Cancer 95
1206-1214 Hidaka H, Ishiko T, Ishikawa S, Ikeda O, Mita S, Iwamura T, Chijiiwa K, Ogawa M (2005) Constitutive IL-8 expression in cancer cells is associated with mutation of p53. Journal of Experimental and Clinical Cancer Research 24 127-133 Hidalgo MA, Romero A, Figueroa J, Cortes P, Concha II, Hancke JL and Burgos RA (2005) Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutrophilic cells. British Journal of Pharmacology 144 680-686 Hideshima T, Chauhan D, Hayashi T, Podar K, Akiyama M, Mitsiades C, MItsiades N, Gong B, Bonham L, De Vries P, Munshi N, Richardson PG, Singer JW and Anderson KC (2003) Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma. Cancer Research 63 8428-8436 Hideshima T,
Chauhan D, Richardson P, Mitsiades C, Mitsiades N, Hayashi T, Munshi N, Dang
L, Castro A, Palombella V, Adams J and Anderson KC (2002) NF-kB as a
therapeutic target in multiple myeloma. Journal of Biological Chemistry 277
16639-16647 Hideshima T,
Chauhan D, Schlossman R, Richardson P and Anderson KC (2001) The role of tumor
necrosis factor alpha in the pathophysiology of human multiple myeloma:
therapeutic applications. Oncogene 20 4519-4527 Hideshima T, Hayashi T, Chauhan D, Akiyama M, Richardson P and Anderson K (2003) Biologic sequelae of c-Jun NH(2)-terminal kinase (JNK) activation in multiple myeloma cell lines. Oncogene 22 8797-8801 Hideshima T, Neri P, Tassone P, Yasui H,Ishitsuka K, Raje N, Chauhan D, Podar K, Mitsiades C, Dang L, Munshi N, Richardson P, Schenkein D and Anderson KC (2006) MLN120B, a novel IkB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo. Clinical Cancer Research 12 5887-5894 Hidi R,
Riches V, Al-Ali M, Cruikshank WW, Center DM, Holgate ST and Djukanovic R
(2000) Role of B7-CD28/CTLA-4 costimulation and NF-B in allergen-induced T
cell chemotaxis by IL-16 and RANTES. Journal of Immunology 164 412-418 Hidvegi T, Schmidt BZ, Hale P, Perlmutter DH (2005) Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkB, and BAP31 but not the unfolded protein response Journal of Biological Chemistry 280 39002-39015 Hiebenthal-Millow K, Pohlmann S, Munch J and Kirchhoff F (2004) Differential regulation of human immunodeficiency virus type 2 and simian immunodeficiency virus promoter activity. Virology 324 501-509 Hierholzer C, Billiar TR and Tweardy DJ (2002) Requirements for NF-kB activation in hemorrhagic shock. Arch Orthop Trauma Surg 122 44-47 Hierholzer C, Billiar TR, Tweardy DJ and Harbrecht B (2003) Reduced hepatic transcription factor activation and expression of IL-6 and ICAM-1 after hemorrhage by NO scavenging. Arch Orthop Trauma Surg 123 55-59
Hierholzer C,
Kalff JC, Audolfsson G, Billiar TR, Tweardy DJ and Bauer AJ (1999) Molecular
and functional contractile sequelae of rat intestinal ischemia/reperfusion
injury. Transplantation 68 1244-1254 Hierholzer C, Kalff JC, Billiar TR, Bauer AJ, Tweardy DJ and Harbrecht BG (2004) Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock. American Journal of Physiology: Gastrointestinal and Liver Physiology 286 G225-G233 Hietaranta A, Mustonen H, Puolakkainen P, Haapiainen R and Kemppainen E (2004) Proinflammatory effects of pancreatic elastase are mediated through TLR4 and NF-kB. Biochemical and Biophysical Research Communications 323 192-196
Hietaranta
AJ, Saluja AK, Bhagat L, Singh VP, Song AM and Steer ML (2001) Relationship
between NF-kB and trypsinogen activation in rat pancreas after supramaximal
caerulein stimulation. Biochemical and Biophysical Research Communications
280 388-395 Hietaranta
AJ, Singh VP, Bhagat L, van Acker GJ, Song AM, Mykoniatis A, Steer ML and Saluja
AK (2001) Water immersion stress prevents caerulein-induced pancreatic acinar
cell NF-kB activation by attenuating caerulein-induced intracellular Ca2+
changes. Journal of Biological Chemistry 276 18742-18747 Higa M, Shimabukuro M, Shimajiri Y, Takasu N, Shinjyo T and Inaba T (2006) Protein kinase B/Akt signalling is required for palmitate-induced beta-cell lipotoxicity. Diabetes and Obesity Metabolism 8 228-233 Higai K, Ishihara S and Matsumoto K (2006) NFkB-p65 dependent transcriptional regulation of glycosyltransferases in human colon adenocarcinoma HT-29 by stimulation with tumor necrosis factor alpha. Biological & Pharmaceutical Bulletin 29 2372-2377 Higai
K, Sano R, Satake M, Azuma Y and Matsumoto K (2007) Glycated human serum
albumin induces interleukin 8 mRNA expression through reactive oxygen species
and NADPH oxidase-dependent pathway in monocyte-Derived U937 cells. Higai K, Shimamura A and Matsumoto K (2006) Amadori-modified glycated albumin predominantly induces E-selectin expression on human umbilical vein endothelial cells through NADPH oxidase activation. Clinica Chimica Acta 367 137-143 Higashihara H, Kokura S, Imamoto E, Ueda M, Naito Y, Yoshida N and Yoshikawa T (2004) Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells. Redox Reports 9 365-369 Higashitsuji H, Higashitsuji H, Liu Y, Masuda T, Fujita T, Abdel-Aziz HI, Kongkham S, Dawson S, Mayer RJ, Itoh Y, Sakurai T, Itoh K and Fujita J (2007) The oncoprotein gankyrin interacts with RelA and suppresses NF-kB activity. Biochemical and Biophysical Research Communications 363 879-884 Higashitsuji
H, Higashitsuji H, Nagao T, Nonoguchi K, Fujii S, Itoh K and Fujita J (2002) A
novel protein overexpressed in hepatoma accelerates export of NF-kappaB from
the nucleus and inhibits p53-dependent apoptosis. Cancer Cell 2 335-46 Higashimoto T, Panopoulos A, Hsieh CL and Zandi E (2006) TNFa induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways. Cytokine 34 39-50
Higashiyama K-I, Niiya K, Ozawa T, Hayakawa Y, Fujimaka M and Sakuragawa N (1996) Induction of c-fos protooncogene transcription and apoptosis by delta12-prostaglandin J2 in human Pl-21 myeloid leukemia and RC-K8 Pre-B lymphoma cells. Prostaglandins 52 143-156 Higgins GT, Wang JH, Dockery P, Cleary PE, Redmond HP (2003) Induction of angiogenic cytokine expression in cultured RPE by ingestion of oxidized photoreceptor outer segments. Investigative Ophthalmology & Visual Science 44 1775-1782 Higgins KA, Perez JR, Coleman TA, Dorshkind K, McComas WA, Sarmiento UM, Rosen CA and Narayanan R (1993) Antisense inhibition of the p65 subunit of NF-kB blocks tumorigenicity and causes tumor regression. Proceedings of the National Academy of Sciences USA 90 9901-9905 Higuchi M, Izumi KM and Kieff E (2001) Epstein-Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors. Proceedings of the National Academy of Sciences USA 98 4675-4680 Higuchi M, Matsuda T, Mori N, Yamada Y, Horie R, Watanabe T, Takahashi M, Oie M and Fujii M (2005) Elevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-kB activation. Retrovirology 2 29 Higuchi Y, Otsu K, Nishida K, Hirotani S, Nakayama H, Yamaguchi O, Hikoso S, Kashiwase K, Takeda T, Watanabe T, Mano T, Matsumura Y, Ueno H and Hori M (2003) The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating Kinase 1 and NF-kB. Journal of Biological Chemistry 278 20770-20777 Higuchi M, Manna SK, Sasaki R and Aggarwal BB (2002) Regulation of the activation of nuclear factor kB by mitochondrial respiratory function: evidence for the reactive oxygen species-dependent and -independent pathways. Antioxidant and Redox Signaling 4 945-955
Higuchi M, Matsuo A, Shingai M, Shida K, Ishii A Funami K, Suzuki Y, Oshiumi
H, Matsumoto M and Seya T (2007) Combinational recognition of bacterial
lipoproteins and peptidoglycan by chicken Toll-like receptor 2 subfamily.
Higuchi M,
Singh S, Chan H and Aggarwal BB (1995) Protease inhibitors differentially
regulate tumor necrosis factor-induced apoptosis, nuclear factor-kB
activation, cytotoxicity, and differentiation. Blood 86 2248-2256
Higuchi T, Watanabe Y and Waga I (2004) Higuchi Y, Chan TO, Brown MA, Zhang J, Degeroge Jr BR, Runakoshi H, Gibson G, McTiernan CF, Kubota T, Jones WK and Feldman AM (2005) Cardioprotecton afforded by NF-kB ablation is associated with activation of Akt in mice over-expressing TNFa. American Journal of Physiology: Heart and Circulatory Physiology 290 H590-H598
Higuchi Y,
Ito M, Tajima M, Higuchi S, Miyamoto N, Nishio M, Kawano M, Kusagawa S,
Tsurudome M, Sudo A, Katou K, Uchida A and Ito Y (1999) Gene expression during
osteoclast-like cell formation induced by antifusion regulatory
protein-1/CD98/4F2 monoclonal antibodies (MAbs): c-src is selectively induced
by anti-FRP-1 MAb. Bone 25 17-24 Higuchi Y, Kawakami S, Oka M, Yabe Y, Yamashita F and Hashida M (2006) Intravenous administration of mannosylated cationic liposome/NF-kB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model. FEBS Letters 580 3706-3714 Higuchi Y,
Otsu K, Nishida K, Hirotani S, Nakayama H, Yamaguchi O, Matsumura Y, Ueno H,
Tada M and Hori M (2002) Involvement of reactive oxygen species-mediated NF-kB
activation in TNF-alpha-induced cardiomyocyte hypertrophy. Journal of Molecular
and Cellular Cardiology
34 233-240 Hii CS, SUn GW, Goh JW, Lu J, Stevens MP and Gan YH (2008) Interleukin-8 induction by Burkholderia pseudomallei can occur without Toll-like receptor signaling but requires a functional type III secretion system. Journal of Infectious Disease in press Hijikata M,
Tsuchihara K, Marusawa H and Shimotohno K (1999) Regulation of cell
proliferation by hepatitis C virus (Article in Japanese]. Tanpakushitsu Kakusan Koso 44 1543-1551 Hijikawa T, Kaibori M, Uchida Y, Yamada M, Matsui K, Ozaki T, Kamiyama Y, Nishizawa M and Okumura T (2007) Insulin-like growth factor 1 prevents liver injury through the inhibition of TNF-a and INos induction in d-galactosamine and LPS-treated rats. Shock in press Hijioka K, Matsuo S, Eto-Kimura A, Takeshige K and Muta T (2007) Induction of the nuclear IkB protein IkB-zeta upon stimulation of B cell antigen receptor. Biochemical and Biophysical Research Communications 356 476-480 Hikichi Y,
Matsui H, Tsuji I, Nishi K, Yamada T, Shintani Y and Onda H (2001) LIGHT, a
member of the TNF superfamily, induces morphological changes and delays
proliferation in the human rhabdomyosarcoma cell line RD. Biochemical and
Biophysical Research Communications 289 670-677 Hikiji H, Takato T, Shimizu T and Ishii S (2008) The roles of prostanoids, leukotrienes, and platelet-activating factor in bone metabolism and disease. Progress in Lipid Research in press Hikishim S, Minakawa N, Kuramoto K, Ogata S and Matsuda A (2006) Synthesis and characterization of oligodeoxynucleotides containing naphthyridine:imidazopyridopyrimidine base pairs at their sticky ends: application as thermally stabilized Decoy molecules. Chembiochem 7 1970-1975 Hikita A and Tanaka S (2007) Ectodomain shedding of receptor activator of NF-kB ligand. Advances in Experimental Medicine and Biology 602 15-21 Hildeman DA,
Zhu Y, Mitchell TC, Kappler J and Marrack P (2002) Molecular mechanisms of
activated T cell death in vivo. Current Opinions in Immunology 14 354-359 Hildt E and
Hofschneider PH (1998) The PreS2 activators of the hepatitis B virus:
activators of tumour promoter pathways. Recent Results Cancer Research 154
315-329 Hilgarth RS, Murphy LA, Skaggs HS, Wilkerson DC, Xing H and Sarge KD (2004) Regulation and function of SUMO modification. Journal of Biological Chemistry 279 53899-53902 Hilgendorff A, Muth H, Parviz B, Staubitz A, Haberbosch W, Tillmanns H and Holschermann H (2003) Statins differ in their ability to block NF-kB activation in human blood monocytes. Int Journal of Clinical Pharmacology and Therapy 41 397-401 Hill A, McFarlane S, Mulligan K, Gillespie H, Draffin JE, Trumble A, Ouhtit A, Johnstron PG, Harkin DP, McCormick D and Waugh DJ (2006) Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells. Oncogene 25 6079-6091
Hill DB,
Barve S, Joshi-Barve S and McClain C (2000) Increased monocyte Nuclear
Factor-kB activation and tumor necrosis factor production in alcoholic
hepatitis. J Lab Clin Med 135 387-395 Hill DB,
Devalaraja R, Joshi-Barve S, Barve S and McClain CJ (1999) Antioxidants
attenuate nuclear factor-kB activation and tumor necrosis factor-a production
in alcoholic hepatitis patient monocytes and rat Kupffer cells, in vitro. Clinical
Biochemistry 32 563-570 Hill DB, McClain CJ, St Clair D and Barve S (2003) Use of transfected liver cells to evaluate potential mechanisms of alcohol-induced liver injury. Alcohol Clin Exp Res 22 785-788 Hill M, Tanguy-Royer S, ROyer P, Chauveau C, Asghar K, Tesson L, Lavainne F, Remy S, Brion R, Hubert FX, Heslan M, Rimbert M, Berthelot L, Moffett JR, Josien R, Gregoire M and Anegon I (2007) IDO expands human CD4(+)CD25(high) regulatory T cells by promoting maturation of LPS-treated dendritic cells. European Journal of Immunology 37 3054-3062 Hill RP, Macneil S and Haycock JW (2005) Melanocyte stimulating hormone peptides inhibit TNF-a signaling in human dermal fibroblast cells. Peptides 27 421-4430 Hill SC, Youde SJ, Man S, Teale GR, Baxendale AJ, Hislop A, Davies CC, Luesley DM, Blom AM, Rickinson AB, Young LS and Eliopoulos AG (2005) Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis. Journal of Immunology 174 41-50 Hill WD, Hess
DC, Carroll JE, Wakade CG, Howard EF, Chen Q, Cheng C, Martin-Studdard A,
Waller JL and Beswick RA (2001) The NF-kB inhibitor diethyldithiocarbamate
(DDTC) increases brain cell death in a transient middle cerebral artery
occlusion model of ischemia. Brain Research Bulletin 55 375-386 Hilliard B,
Samoilova EB, Liu TS, Rostami A and Chen Y (1999) Experimental autoimmune
encephalomyelitis in NF-kB-deficient mice:roles of NF-kB in the activation and
differentiation of autoreactive T cells. Journal of Immunology 163 2937-2943 Hilliard BA,
Mason N, Xu L, Sun J, Lamhamedi-Cherradi SE, Liou HC, Hunter C and Chen YH
(2002) Critical roles of c-Rel in autoimmune inflammation and helper T cell
differentiation. Journal of Clinical Investigation 110 843-850 Hillman K,
Qian J, Siegel JN, Roderiquez G, Blackburn R, Manishewitz J, Norcross M and
Golding H (1992) Reduced susceptibility to HIV-1 infection of
ethyl-methanesulfonate-treated CEM subclones correlates with a blockade in
their protein kinase C signaling subclones correlates with a blockade in their
protein kinase C signaling pathway. Journal of Immunology 148 3991-3998 Hilmi F, Gertsch J, Bremner P, Valovic S, Heinrich M, Sticher O and Heilmann J (2003) Cytotoxic versus anti-inflammatory effects in HeLa, Jurkat T and human peripheral blood cells caused by guaianolide-type sesquiterpene lactones. Bioorganic and Medicinal Chemistry 11 3659-3663 Himes SR,
Coles LS, Katsikeros R, Lang RK and Shannon MF (1993) HTLV-1 tax activation of
the GM-CSF and G-CSF promoters requires the interaction of NF-kB with other
transcription factor families. Oncogene 8 3189-3197 Himes SR,
Coles LS, Reeves R and Shannon MF (1996) High mobility group protein I(Y) is
required for function and for c-Rel binding to CD28 response elements within
the GM-CSF and IL-2 promoters. Immunity 5 479-489 Himes SR,
Katsikeros R and Shannon MF (1996) Costimulation of cytokine gene expression
in T cells by the human T leukemia/lymphotropic virus type 1 trans
actvator Tax. Journal of Virology 70 4001-4008 Hinata K, Gervin AM, Jennifer Zhang Y and Khavari PA (2003) Divergent gene regulation and growth effects by NF-kB in epithelial and mesenchymal cells of human skin. Oncogene 22 1955-1964 Hino R, Uozaki H,Inoue Y, Shintani Y, Ushiku T, Sakatani T, Takada K and Fukayama M (2008) Survival advantage of EBV-associated gastric carcinoma: survivin up-regulation by viral latent membrane protein 2A. Cancer Research 68 1427-1435 Hinokiyama K, Valen G, Tokuno S, Vedin JB and Vaage J (2006) Vein graft harvesting induces inflammation and impairs vessel reactivity. Annals of Thoracic Surgery 82 1458-1464 Hinrichs SH,
Nerenberg M, Reynolds RK, Khoury G and Jay G (1987) A transgenic mouse model
for human neurofibromatosis. Science 237 1340-1343 Hinshaw-Makepeace J, Huston G, Fortner KA, Russell JQ, Holoch D, Swain S and Budd RC (2008) c-FLIP(S) reduces activation of caspase and NF-kB pathways and decreases T cell survival. European Journal of Immunology 38 54-63 Hinthong O, Jin XL and Shisler JL (2008) Characterization of wild-type and mutant vaccinia virus M2L proteins' abilities to localize to the endoplasmic reticulum and to inhibit NF-kB activation during infection. Virology in press Hinz M, Broemer M, Col Arslan S, Otto A, Mueller EC, Dettmer R and Scheidereit C (2007) Signal-responsiveness of IkB kinases is determined by Cdc37-assisted transient interaction with Hsp90. Journal of Biological Chemistry 181 32311-32319 Hinz M,
Krappmann D, Eichten A, Heder A, Scheidereit C and Strauss M (1999) NF-kB
function in growth control: regulation of cyclin D1 expression and
G0/G1-to-S-phase transition. Molecular and Cellular Biology 19 2690-2698 Hinz M, Lemke
P, Anagnostopoulos I, Hacker C, Krappmann D, Mathas S, Dorken B, Zenke M,
Stein H and Scheidereit C (2002) Nuclear factor kB-dependent gene expression
profiling of Hodgkin's Disease tumor cells, pathogenetic significance, and
link to constitutive signal transducer and activator of transcription 5a
activity. Journal of Experimental Medicine 196 605-617 Hinz M, Loser
P, Mathas S, Krappmann D, Dorken B and Scheidereit C (2001) Constitutive NF-kB
maintains high expression of a characteristic gene network, including CD40
CD86, and a set of antiapoptic genes in Hodgkin/Reed-Sternberg cells. Blood 97
2798-2807 Hinz M, Löser
P, Mathas S, Krappmann D, Dörken, Scheidereit C (2002) Constitutive NF-kB
maintains high expression of a characteristic gene network, incuding CD40,CD86
and a set of antiapoptotic genes in Hodgkin/Reed-Steinberg cells. Blood 97
2798-2807 Hinz M and Scheidereit C (2007) Striking back at the activator: how IkappaB kinase terminates antigen receptor responses. Science STKE 2007(384) pe19 Hipp MS,
Urbich C, Mayer P, Wischhusen J, Weller M, Kracht M and Spyridopoulos I (2002)
Proteasome inhibition leads to NF-kB-independent IL-8 transactivation in human
endothelial cells through induction of AP-1. European Journal of Immunology 32
2208-2217 Hippenstiel
S, Schmeck B, Seybold J, Krull M, Eichel-Streiber C and Suttorp N (2002)
Reduction of tumor necrosis factor-alpha (TNF-alpha) related nuclear factor-kB
(NF-kB) translocation but not inhibitor k-B (Ik-B)-degradation by Rho protein
inhibition in human endothelial cells. Biochemical Pharmacology 64 971-977 Hirahashi J,
Takayanagi A, Hishikawa K, Takase O, Chikaraishi A, Hayashi M, Shimizu N and
Saruta T (2000) Overexpression of truncated IkB alpha potentiates
TNF-a-induced apoptosis in mesangial cells. Kidney International 57 959-968 Hirai H,
Fujisawa J, Suzuki T, Ueda K, Muramatsu M, Tsuboi A, Arai N and Yoshida M
(1992) Transcriptional activator Tax of HTLV-1 binds to the NF-kB precursor
p105. Oncogene 7 1737-1742 Hirai
H, Shibata T, Aoyama T, Yoshiyama M, Omura T and Suehiro S (2006) Activation
of mitogen-activated protein kinases, activator protein-1, and nuclear
factor-kB during acute rejection after heterotopic heart transplantation in
rats. Hirai H,
Suzuki T, Fujisawa J-i, Inoue J-i and Yoshida M (1994) Tax protein of human
T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor
kB and induces nuclear translocation of transcription factor NF-kB proteins
for transcriptional activation. Proceedings of the National Academy of
Sciences USA 91 3584-3588 Hiramatsu N, Kasai A, Hayakawa K, Nagai K, Kubota T, Yao J andKitamura M (2006) Secreted protein-based reporter systems for monitoring inflammatory events: Critical interference by endoplasmic reticulum stress. Journal of Immunological Methods 315 202-207 Hiramatsu T, Yasuda T, Ito H, Shimizu M, Julovi SM, Kakinuma T, Akiyoshi M, Yoshida M and Nakamura T (2006) Intercellular adhesion molecule-1 mediates the inhibitory effects of hyaluronan on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts via down-regulation of NF-kB and p38. Rheumatology 45 824-832 Hiramoto M,
Shimizu N, Nishi T, Shima D, Aizawa S, Tanaka H, Hatakeyama M, Kawaguchi H and
Handa H (2002) High-performance affinity beads for identifying anti-NF-kB drug
receptors. Methods in Enzymology 353 81-88 Hiramoto M,
Shimizu N, Sugimoto K, Tang J, Kawakami Y, Ito M, Aizawa S, Tanaka H, Makino I
and Handa H (1998) Nuclear targeted suppresion of NF-kB activity by novel
quinone derivative E3330. Journal of Immunology 160 810-819 Hirani N,
Antonicelli F, Strieter RM, Wiesener MS, Ratcliffe PJ, Haslett C and Donnelly
SC (2001) The regulation of interleukin-8 by hypoxia in human macrophages--a
potential role in the pathogenesis of the acute respiratory distress syndrome
(ARDS). Molecular Medicine 7 685-697 Hirano A and
Wong T (1988) Functional interactions between transcriptional elements in the
long terminal repeat of reticuloendotheliosis virus:cooperative DNA binding of
promoter- and enhancer-specific factors. Molecular and Cellular Biology 8
5232-5244 Hirano F,
Chung M, Tanaka H, Maruyama N, Makino I, Moore D and Scheidereit C (1998)
Alternate splicing variants of IkBb establish differential NF-kB signal
responsiveness in human cells. Molecular and Cellular Biology 18 2596-2607 Hirano F, Haneda M and Makino I (2006) Chenodeoxycholic acid and taurochenodexycholic acid induce anti-apoptotic cIAP-1 expression in human hepatocytes. Journal of Gastroenterology and Hepatology 21 1807-1813 Hirano F,
Kobayashi A, Hirano Y, Nomura Y, Fukawa E and Makino I (2001) Bile acids
regulate RANTES gene expression through its cognate NF-kB binding sites.
Biochemical and Biophysical Research Communications 288 1095-1101 Hirano F, Kobayashi A and Makino I (2003) Inhibition of TNF-a-induced RANTES expression in human hepatocyte-derived cells by fibrates, the hypolipidemic drugs. International Immunopharmacology 3 225-232 Hirano F, Komura K, Fukawa E and Makino I (2003) Tumor necrosis factor alpha (TNF-alpha)-induced RANTES chemokine expression via activation of NF-kB and p38 MAP kinase: roles of TNF-alpha in alcoholic liver diseases. Journal of Hepatology 38 483-489
Hirano F,
Tanaka H, Miura T, Hirano Y, Okamoto K, Makino Y and Makino I (1998)
Inhibition of NF-kB-dependent transcription of human immunodeficiency virus 1
promoter by a phosphodiester compound of vitamin C and vitamin E, EPC-K1.
Immunopharmacology 39 31-38 Hirano M,
Osada S-i, Aoki T, Hirai S-i, Hosaka M, Inoue J-i and Ohno S (1996) MEK kinase
is involved in tumor necrosis factor a-induced NF-kB activation and
degradation of IkB-a. Journal of Biological Chemistry 271 13234-13238 Hirano S, Furutama D and Hanafusa T (2006) Physiologically high concentrations of 17-beta-estradiol enhance NF-kB activity in human T cells. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology in press Hirano Y,
Hirano F, Fujii H and Makino I (2002) Fibrates suppress chenodeoxycholic
acid-induced RANTES expression through inhibition of NF-kB activation.
European Journal of Pharmacology 448 19-26 Hiraoka S,
Miyazaki Y, Kitamura S, Toyota M, Kiyohara T, Shinomura Y, Mukaida N and
Matsuzawa Y (2001) Gastrin induces CXC chemokine expression in gastric
epithelial cells through activation of NF-kB. Am J Physiol Gastrointest Liver
Physiol 281 G735-G742 Hiraoka W,
Vazquez N, Nieves-Neira W, Chanock SJ and Pommier Y (1998) Role of oxygen
radicals generated by NADPH oxidase in apoptosis induced in human leukemia cells. Journal of Clinical Investigation 102 1961-1968 Hirasaka K, Nikawa T, Yuge L, Ishihara I, Higashibata A, Ishioka N, Okubo A, Miyashita T, Suzue N, Ogawa T, Oarada M and Kishi K (2005) Clinorotation prevents differentiation of rat myoblastic L6 cells in association with reduced NF-kB signaling. Biochimica et Biophysica Acta 1743 130-140 Hirata I, Yasumoto S, Toshina K, Inoue T, Nishikawa T, Murano N, Murano M, Wang FY and Katsu K (2007) Evaluation of the effect of pyrrolidine dithiocarbamate in suppressing inflammation in mice with dextran sodium sulfate-induced colitis. World Journal of Gastroenterology 13 1666-1671 Hirata T, Osuga Y, Hirota Y, Koga K, Yoshino O, Harada M, Morimoto C, Yano T, Nishii O, Tsutsumi O and Taketani Y (2005) Evidence for the presence of Toll-like receptor (TLR) 4 system in the human endometrium. Journal of Clinical Endocrinology and Metabolism 90 548-556 Hirata Y, Masuda Y, Kakutani H, Iiguchi T, Takada K, Ito A, Nakagawa Y and Ishi H (2008) Sp1 is an essential transcription factor for LPS-induced tissue factor expression in THP-1 monocytic cells, and nobiletin represses the expression through inhibition of NF-kB, AP-1, and Sp1 activation. Biochemical Pharmacology in press Hirata Y,
Maeda S, Mitsuno Y, Akanuma M, Yamaji Y, Ogura K, Yoshida H, Shiratori Y and
Omata M (2001) Helicobacter pylori activates the cyclin D1 gene through
mitogen- activated protein kinase pathway in gastric cancer cells. Infection
and Immunity 69 3965-3971 Hirata Y, Maeda S, Ohmae T, Shibata W, Yanai A, Ogura K, Yoshida H, Kawabe T and Omata M (2006) Helicobacter pylori induces IkB kinase alpha nuclear translocation and chemokine production in gastric epithelial cells. Infection and Immunity 74 1452-1461 Hirata Y, Ohmae T, Shibata W, Maeda S, Ogura K, Yoshida H, Kawabe T and Omata M (2006) MyD88 and TNF receptor-associated factor 6 are critical signal transducers in Helicobacter pylori-infected human epithelial cells. Journal of Immunology 176 3796-3803 Hirayama T, Dai S, Abbas S, Yamanaka Y and Abu-Amer Y (2005) Inhibition of inflammatory bone erosion by constitutively active STAT-6 through blockade of JNK and NF-kB activation. Arthritis and Rheumatism 52 2719-2729 Hirohata S, Miura Y, Tomita T, Yoshikawa H, Ochi T and Chiorazzi N (2006) Enhanced expression of mRNA for nuclear factor kB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis. Arthritis Research and Therapy 8 R54 Hiroi M and Ohmori Y (2003) The transcriptional coactivator CBP cooperates with STAT1 and NF-kB for synergistic transcriptional activation of the CXCL9/MIG gene. Journal of Biological Chemistry 278 651-660 Hiroi M and Ohmori Y (2003) Constitutive nuclear factor-kB activity is required to elicit interferon gamma-induced expression of chemokine CXC ligand 9 (CXCL9) and CXCL10 in human tumor cell lines. Biochem J 376 393-402 Hiroki J, Shimokawa H, Higashi M, Morikawa K, Kandabashi T, Kawamura N, Kubota T, Ichiki T, Amano M, Kaibuchi K and Takeshita A (2004) Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells. Journal of Molecular and Cellular Cardiology 37 537-546 Hiroki J, Shimokawa H, Mukai Y, Ichiki T and Takeshita A (2004) Divergent effects of estrogen and nicotine on Rho-kinase expression in human coronary vascular smooth muscle cells. Biochemical and Biophysical Research Communications 326 154-159 Hironaka N, Mochida K, Mori N, Maeda M, Yamamoto N and Yamaoka S (2004) Tax-independent constitutive IkB kinase activation in adult T-cell leukemia cells. Neoplasia 6 266-278 Hirose K,
Suzuki H, Nishimura H, Mitani A, Washizu J, Matsuguchi T and Yoshikai Y (1998)
Interleukin-15 may be responsible for early activation of intestinal
intraepithelial lymphocytes after oral infection with Listeria
monocytogenes in rats. Infection and Immunity 66 5677-5683 Hirose K, Wakashin H, Oki M, Kagami SI, Suto A, Ikeda K, Watanabe N, Iwamoto I, Furuichi Y and Nakajima H (2008) GS143, an IkB ubiquitination inhibitor, inhibits allergic airway inflammation in mice. Biochemical and Biophysical Research Communications in press Hirota K,
Murata M, Itoh T, Yodoi J and Fukuda K (2001) An endogenous redox molecule,
thioredoxin, regulates transactivation of epidermal growth factor receptor and
activation of NF-kB by lysophosphatidic acid. FEBS Letters 489 134-138 Hirota K, Murata M, Itoh T, Yodoi J and Fukuda K (2001) Redox-sensitive transactivation of epidermal growth factor receptor by tumor necrosis factor confers the NF-kB activation. Journal of Biological Chemistry 276 25953-25958 Hirota K,
Murata M, Sachi Y, Nakamura H, Takeuhia J, Mori K and Yodoi J (1999) Distinct
roles of thioredoxin in the cytoplasm and in the nucleus: a two-step mechanism
of redox regulation of transcription factor NF-kB. Journal of Biological
Chemistry 274 27891-27897 Hirota K,
Nakamura H, Arai T, Ishii H, Bai J, Itoh T, Fukuda K and Yodoi J (2000)
Geranylgeranylacetone enhances expression of thioredoxin and suppresses
ethanol-induced cytotoxicity in cultured hepatocytes. Biochemical and
Biophysysical Research Communications 275 825-830 Hirota Y, Osuga Y, Yoshino O, Koga K, Yano T, Hirata T, Nose E, Ayabe T, Namba A, Tsutsumi O and Taketani Y (2003) Possible roles of thrombin-induced activation of protease-activated receptor 1 in human luteinized granulosa cells. J Clin Endocrinol Metab 88 3952-3957 Hirotani S, Otsu K, Nishida K, Higuchi Y, Morita T, Nakayama H, Yamaguchi O, Mano T, Matsumura Y, Ueno H, Tada M and Hori M (2002) Involvement of nuclear factor-kB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation 105 509-515 Hirotani T, Lee PY, Kuwata H, Yamamoto M, Matsumoto M, Kawase I, Akira S and Takeda K (2005) The nuclear IkB protein IkBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria. Journal of Immunology 174 3650-3657 Hiroto R, Akimaru K and Nakamura H (2008) In vitro toxicity evaluation of diesel exhaust particles on human eosinophilic cell. Toxicology In Vitro in press Hirsch B, Hummel M, Bentink S, Fouladi F, Sapng R, Zollinger R, Stein H and Durkop H (2008) CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. American Journal of Pathology in press Hirschfeld
M,
Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM and Weis JJ (1999)
Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is
mediated by toll-like receptor 2. Journal of Immunology 163 2382-2386 Hisada
S, Shimuzu K, Shiratori K and Kobayashi M (2005) Peroxisome
proliferator-activated receptor gamma ligand prevents the development of
chronic pancreatitis through modulating NF-kappaB-dependent proinflammatory
cytokine production and pancreatic stellate cell activation. Hisada T,
Adcock IM, Nasuhara Y, Salmon M, Huang TJ, Barnes PJ and Chung KF (1999)
Inhibition of ozone-induced lung neutrophilia and nuclear factor-kB binding
activity by vitamin A in rat. European Journal of Pharmacology 377 63-68 Hisada Y,
Sakurai H and Sugaya T (2000) Cell to cell interaction between mesangial cells
and macrophages induces the expression of monocyte chemoattractant protein-1
through nuclear factor-kB activation. Biochemical and Biophysical Research
Communications 269 309-316 Hisamori S, Tabata C, Kadokawa Y, Okoshi K, Tabata R, Mori A, Nagayama S, Watanable G, Kubo H and Sakai Y (2008) All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production. Liver International in press Hisaoka T, Morikawa Y, Komori T, Sugiyama T, Kitamura T and Senba E (2006) Characterization of TROY-expressing cells in the developing and postnatal CNS: the possible role in neuronal and glial cell development. European Journal of Neuroscience 23 3149-3160 Hisatake K,
Hasegawa S, Takada R, Nakatani Y, Horikoshi M & Roeder RG (1993) The p250
subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory
protein CCG1. Nature 362 179-181 Hisatsune J, Nakayama M, Isomoto H, Kurazono H, Mukaida N, Mukhopadhyay AK, Azuma T, Yamaoka Y, Sap J, Yamasaki E, Yahiro K, Moss J and Hirayama T (2008) Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kB activation. Journal of Immunology 180 5017-5027 Hisayama T,
Inomoto M, Hioki Y and Fukui H (1999) [Identification of PKC isozymes and
effect of knockdown of PKC alpha by antisense oligodeoxynucleotide on iNOS
expression via interleukin-1 receptor in vascular smooth muscle cells]. Nippon
Yakurigaku Zasshi 114 Suppl 1 86P-91P Hisayama T, Shinohara Y, Fukui H (2002) Expression mechanisms of inducible type nitric oxide synthasegene via interleukin-1 receptor signaling [Article in Japanese]. Nippon Yakurigaku Zasshi 120 76P-78P Hiscott J (2007) Convergence of the NF-kB and IRF pathways in the regulation of the innate antiviral response. Cytokine and Growth Factor Reviews 18 483-490
Hiscott J,
Alper D, Cohen L, LeBlanc, J-F, Sportza L, Wong A and Xanthoudakis S (1989)
Induction of human interferon gene expression is associated with a nuclear
factor that interacts with the NF-kB site of the human immunodeficiency virus
enhancer. Journal of Virology 63 2557-2566 Hiscott J, Grandvaux N, Sharma S, Tenoever BR, Servant MJ and Lin R (2003) Convergence of the NF-kB and interferon signaling pathways in the regulation of antiviral defense and apoptosis. Annals of the New York Academy of Science 1010 237-248
Hiscott J,
Kwon H and Genin P (2001) Hostile takeovers: viral appropriation of the NF-kB
pathway. Journal of Clinical Investigation 107 143-151 Hiscott J,
Kwon H, Génin P (2002) Hostile takeover: viral appropriation of the NF-kB
pathway. The Journal of Clinical Investigation. 107 143-151 Hiscott J,
Marois J, Garoufalis J, D'Addario, Roulston A, Kwan I, Pepin N, LaCoste J,
Nguyen H, Bensi G and Fenton M (1993) Characterization of a functional NF-kB
site in the human interleukin 1b promoter: evidence for a positive
autoregulatory loop. Molecular and Cellular Biology 13 6231-6240 Hiscott J, Nguyen TL, Arguello M, Nakhaei P and Paz S (2006) Manipulation of the nuclear factor-kB pathway and the innate immune response by viruses. Oncogene 25 6844-6867 Hiscott J,
Petropoulos L and Lacoste J (1995) Molecular interactions between HTLV-1 Tax
protein and the NF-kB/IkB transcription complex. Virology 214 3-11 Hishikawa K and Nakaki T (2001) NF-kB as a therapeutic drug target [Article in Japanese]. Nippon Yakurigaku Zasshi 118 197-202 Hishikawa K, Nakaki T and Fujita T (2005) Oral flavonoid supplementation attenuates atherosclerosis development in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 25 442-448 Hishiki T, Ohsima T, Ego T and Shimothno K (2007) BCL3 acts as a negative regulator of transcription from the human T-cell leukima virus type 1 long terminal repeat through interactions with TORC3. JOurnal of Biological Chemistry 282 28335-28343 Hishiya A, Ikeda K and Watanabe K (2005) A RANKL-inducible gene Znf216 in osteoclast differentiation. J Recept Signal Transduct Res 25 199-216 Hitchon CA and El-Gabalawy HS (2004) Oxidation in rheumatoid arthritis. Arthritis Res Ther 6 265-278 Hiura TS, Kempiak SJ and Nel AE (1999) Activation of the human RANTES
gene promoter in a
macrophage cell line by lipopolysaccharide is dependent on stress-activated
protein kinases and the IkB kinase cascade: implications for exacerbation of
allergic inflammation by environmental pollutants. Clinical
Immunology 90 287-301 Hjelmsoe I,
Allen CE, Cohn MA, Tulchinsky EM and Wu LC (2000) The kB and V(D)J
recombination signal sequence binding protein KRC regulates transcription of
the mouse metastasis-associated gene S100A4/mts1. Journal of Biological
Chemistry 275 913-920 Hjerpe R and Rodriguez MS (2008) Alternative UPS drug targets upstream of the 26S proteasome. International Journal of Biochemistry and Cell Biology in press Hjertner O, Standal T, Borset M, Sundan A and Waage A (2005) Identification of new targets for therapy of osteolytic bone disease in multiple myeloma. Current Drug Targets 6 701-711 Hnia K, Gayraud J, Hugon G, Ramontxo M, De La Porte S, Matecki S and Mornet D (2008) L-Arginine decreases inflammation and modulates the nuclear factor-kB/matrix metalloproteinase cascade in Mdx muscle fibers. American Journal of Pathology in press Hnia K, Hugon G, Rivier F, Masmoudi A, Mercier J and Mornet D (2007) Modulation of p38 mitogen-activated protein kinase cascade and metalloproteinase activity in diaphragm muscle in response to free radical scavenger administration in dystrophin-deficient Mdx mice. American Journal of Pathology 170 633-643 Ho CC, Ling YC, Chang LW, Tsai HT, Tsai MH and Lin P (2008) 17 beta estradiol and hydroxyestradiols interact via the NF-kB pathway to elevate cyclo-oxygenase 2 expression and prostaglandin E2 secretion in human bronchial epithelial cells. Toxicological Sciences in press Ho E, Boileau TW and Bray TM (2004) Dietary influences on endocrine-inflammatory interactions in prostate cancer development. Archives of Biochemistry and Biophysics 428 109-117 Ho E and Bray
TM (1999) Antioxidants, NFkB activation, and diabetogenesis. Proceedings of
the Society of Experimental Biology and Medicine 222 205-213 Ho E, Chen G
and Bray TM (1999) Supplementation of N-acetylcysteine inhibits NFkB
activation and protects against alloxan-induced diabetes in CD-1 mice. FASEB
Journal 13 1845-1854 Ho E, Chen G
and Bray TM (2000) Alpha-phenyl-tert-butylnitrone (PBN) inhibits NFkB
activation offering protection against chemically induced diabetes. Free Radic
Biol Med 28 604-614 Ho E, Quan N,
Tsai YH, Lai W and Bray TM (2001) Dietary zinc supplementation inhibits NFkB
activation and protects against chemically induced diabetes in CD1 mice. Exp
Biol Med (Maywood) 226 103-111 Ho FM, Kang HC, Lee ST, Chao Y, Chen YC, Huang LJ and Lin WW (2007) The anti-inflammatory actions of LCY-2-CHO, a carbazole analogue, in vascular smooth muscle cells. Biochemical Pharmacology in press Ho FM, Lai CC, Huang LJ, Kuo TC, Chao CM and Lin WW (2004) The anti-inflammatory carbazole, LCY-2-CHO, inhibits lipopolysaccharide-induced inflammatory mediator expression through inhibition of the p38 mitogen-activated protein kinase signaling pathway in macrophages. British Journal of Pharmacology 141 1037-1047 Ho FM, Lin WW, Chen BC, Chao CM, Yang CR, Lin LY, Lai CC, Liu SH and Liau CS (2005) High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kB and c-Jun NH(2)-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cellular Signaling 18 391-399 Ho L, Davis RE, Conne B, Chappuis R, Berczy M, Mhawech P, Staudt LM, Schwaller J (2004) MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kB dependent proliferative advantage and resistance against FAS-induced cell death in B cells. Blood 105 2891-2899 Ho LH, Ruffin RE, Murgia C, Li L, Krilis SA, Zalewski PD (2004) Labile zinc and zinc transporter ZnT4 in mast cell granules: role in regulation of caspase activation and NF-kB translocation. Journal of Immunology 172 7750-7760 Ho LJ, Juan TY, Chao P, Wu WL, Chang DM, Chang SY and Lai JH (2004) Plant alkaloid tetrandrine downregulates IkBa kinases-IkBa-NF-kB signaling pathway in human peripheral blood T cell. British Journal of Pharmacology 143 919-927 Ho LJ, Lin LC, Hung LF, Wang SJ, Lee CH, Chang DM, Lai JH and Tai TY (2005) Retinoic acid blocks pro-inflammatory cytokine-induced matrix metalloproteinase production by down-regulating JNK-AP-1 signaling in human chondrocytes. Biochemical Pharmacology 70 200-208 Ho LL, Chen
WJ, Lin-Shiau SY and Lin JK (2002) Penta-O-galloyl-beta-D-glucose inhibits the
invasion of mouse melanoma by suppressing metalloproteinase-9 through down-regulation of activator protein-1. European Journal of Pharmacology 453
149-158 Ho RC, Hirshman MF, Li Y, Cai D, Farmer JR, Aschenbach WG, Witczak CA, Shoelson SE and Goodyear LJ (2005) Regulation of IkB kinase and NF-kB in contracting adult rat skeletal muscle. American Journal of Physiology: Cell Physiology 289 C794-C801 Ho
SM, Leung YK and Chung I (2006) Estrogens and antiestrogens as etiological
factors and therapeutics for prostate cancer. Ho SN, Thomas
DJ, Timmerman LA, Li X, Francke U and Crabtree GR (1995) NFATc3, a
lymphoid-specific NFATc family member that is calcium-regulated and exhibits
distinct DNA binding specificity. Journal of Biological Chemistry 270
19898-19907 Ho TY and Bagnell CA (2005) Relaxin induces matrix metalloproteinase-9 through activation of nuclear factor kB in human THP-1 cells. Annals of the New York Academy of Sciences 1041 314-316 Ho TY, Yan W and Bagnell CA (2007) Relaxin-induced matrix metalloproteinase-9 expression is associated with activation of the NF-kB pathway in human THP-1 cells. Journal of Leukocyte Biology 81 1303-1310 Ho WC, Dickson KM and Barker PA (2005) Nuclear factor-kB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kB-dependent transcription in cancer cells. Cancer Research 65 4273-4281 Ho YW, Yeung JS, Chiu PK, Tang WM, Lin ZB, Man RY and Lau CS (2007) Ganoderma lucidum polysaccharide peptide reduced the production of proinflammatory cytokines in activated rheumatoid synovial fibroblast. Molecular and Cellular Biochemistry 301 173-179 Hoare GS,
Chester AH, Yacoub MH and Marczin N(2001) Regulation of NF-kB and ICAM-1
expression in human airway epithelial cells. International Journal of
Molecular Medicine 9 35-44 Hoare GS,
Marczin N, Chester AH and Yacoub MH (1999) Role of oxidant stress in
cytokine-induced activation of NF-kB in human aortic smooth muscle cells.
American Journal of Physiology 277
H1975-H1984 Hoberg JE, Popko AE, Ramsey CS and Mayo MW (2006) IkB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. Molecular and Cellular Biology 26 457-471 Hoberg JE, Yeung F and Mayo MW (2004) SMRT Derepression by the IkB kinase alpha; a prerequisite to NF-kB transcription and survival. Molecular Cell 16 245-255 Hochart H, Vincent Jenkins P, Smith OP and White B (2006) Low-molecular weight and unfractionated heparins induce a downregulation of inflammation: decreased levels of proinflammatory cytokines and nuclear factor-kB in LPS-stimulated human monocytes. British Journal of Haematology 133 62-67 Hochegger K, Perco P, Enrich J, Mayer B, Mayer G, Rosenkranz AR and Rudnicki M (2007) In vitro- transcriptional response of polymorphonuclear leukocytes following contact with different antigens. European Journal of Clinical Investigation 37 860-869 Hochrainer K, Racchumi G and Anrather J (2007) Hypo-phosphorylation leads to nuclear retention of NF-kB p65 due to impaired IkBa gene synthesis. FEBS Letters in press Hochstrasser
M (1996) Protein degradation or regulation: Ub the judge. Cell 84 813-815 Hochwald SN, Lind DS, Malaty J, Copeland EM 3rd, Moldawer LL and MacKay SL (2003) Antineoplastic therapy in colorectal cancer through proteasome inhibition. American Surgery 69 15-23 Hodge JC, Bub J, Kaul S, Kajdacsy-Balla A and Lindholm PF (2003) Requirement of RhoA activity for increased nuclear factor kB activity and PC-3 human prostate cancer cell invasion. Cancer Research 63 1359-1364
Hodgson J and
Enrietto PJ (1995) Constitutive and inducible kB binding activities in the
cytosol of v-Rel-transformed lymphoid cells. Journal of Virology 69 1971-1979 Hodgson L, Henderson AJ and Dong C (2003) Melanoma cell migration to type IV collagen requires activation of NF-kB. Oncogene 22 98-108
Hodin R
(2000) Maintaining gut homeostasis: the butyrate-NF-kB connection. [editorial;
comment]. Gastroenterology 118 798-801 Hoeflich K,
Luo J, Rubie E, Tsao M, Jin O and Woodgett J (2000) Requirment for glycogen
synthase kinase-3b in cell survival and NF-kB activation. Nature 406 86-90 Hoelzer JD,
Franklin RB and Bose Jr HR (1979) Transformation by reticuloendotheliosis
virus:development of a focus assay and isolation of a nontransforming virus.
Virology 93 20-30 Hoelzer JD,
Lewis RB, Wasmuth CR and Bose Jr HR (1980) Hematopoietic cell transformation
by reticuloendotheliosis virus:characterization of the genetic defect.
Virology 100 462-474 Hoentjen F, Sartor RB, Ozaki M and Jobin C (2005) STAT3 regulates NF-kB recruitment to the IL-12p40 promoter in dendritic cells. Blood 105 689-696 Hofbauer LC,
Kluger S, Kuhne CA, Dunstan CR, Burchert A, Schoppet M, Zielke A and Heufelder
AE (2002) Detection and characterization of RANK ligand and osteoprotegerin in
the thyroid gland. Journal of Cell Biochemistry 86 642-650 Hofbauer LC, Rachner T and Singh SK (2008) Single-walled carbon nanotubes can induce pulmonary injury in mouse model. Breast Cancer Research 10 101 Hofbauer LC,
Shui C, Riggs BL, Dunstan CR, Spelsberg TC, O'Brien T and Khosla S (2001)
Effects of immunosuppressants on receptor activator of NF-kB ligand and
osteoprotegerin production by human osteoblastic and coronary artery smooth
muscle cells. Biochemical and Biophysical Research Communications 280 334-339 Hofbauer LC,
Ten RM and Khosla S (1999) The anti-androgen hydroxyflutamide and androgens
inhibit interleukin-6 production by an androgen-responsive human osteoblastic
cell line. Journal of Bone and Mineral Research 14 1330-1337 Hofer S, Eisenbach C, Lukic IK, Schneider L, Bode K, Brueckmann M, Mautner S, Wente MN, Encke J, Werner J, Dalpke AH, Stremmel W, Nawroth PP, Martin E, Krammer PH, Bierhaus A and Weigand MA (2007) Pharmacologic cholinesterase inhibition improves survival in experimental sepsis. Critical Care Medicine in press Hofer S,
Rescigno M, Granucci F, Citterio S, Francolini M and Ricciardi-Castagnoli P
(2001) Differential activation of NF-kB subunits in dendritic cells in
response to Gram-negative bacteria and to lipopolysaccharide. Microbes and Infection
3 259-265 Hoffjan S, Parwez Q, Petrasch-POarwez E, Falkenstein D, Nothnagel M and Epplen JT (2006) Association screen for atopic dermatitis candidate gene regions using microsatellite markers in pooled DNA samples. International Journal of Immunogenetics 33 401-409 Hoffmann A and Baltimore D (2006) Circuitry of nuclear factor kB signaling. Immunological Reviews 210 171-178 Hoffmann A, Levchenko A, Scott ML and Baltimore D (2002) The IkB-NF-kB signaling module: temporal control and selective gene activation. Science 298 1241-1245 Hoffmann A, Leung TH and Baltimore D (2003) Genetic analysis of NF-kB transcription factors defines functional specificities. EMBO Journal 22 5530-5539 Hoffmann A, Natoli G and Ghosh G (2006) Transcriptional regulation via the NF-kB signaling module. Oncogene 25 6706-6716 Hoffmann A, Xia Y adn Verma IM (2007) Inflammatory tales of liver cancer. Cancer Cell 11 99-101 Hoffmann E, Thiefes A, Buhrow D, Dittrich-Breiholz O, Schneider H, Resch K and Kracht M (2005) MEK1-dependent delayed expression of FRA-1 counteracts c-FOS and p65 NF-kB-mediated interleukin-8 transcription in response to cytokines or growth factors. Journal of Biological Chemistry 280 9706-9718 Hofmann CS and Sonenshein GE (2003) Green tea polyphenol epigallocatechin-3 gallate induces apoptosis of proliferating vascular smooth muscle cells via activation of p53. FASEB Journal 17 702-704
Hoffmann G,
Rieder J, Smolny M, Seibel M, Wirleitner B, Fuchs D and Schobersberger W
(1999) Neopterin-induced expression of intercellular adhesion molecule-1
(ICAM-1) in type II-like alveolar epithelial cells. Clinical and Experimental Immunology 118
435-440 Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, Anderson JP, Wanderer AA and Firestein GS (2004) Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 364 1779-1785 Hoffmann JA (2003) The immune reponse of Drosophila. Nature 426 33-38 Hoffmann M,
Schmidt M and Wels W (1998) Activation of EGF receptor family members
suppresses the cytotoxic effects of tumor necrosis factor-a. Cancer Immunology
and Immunotherapy 47 167-175 Hofmann MA,
Schiekofer S, Isermann B, Kanitz M, Henkels M, Joswig M, Treusch A, Morcos M,
Weiss T, Borcea V, Abdel Khalek AK, Amiral J, Tritschler H, Ritz E, Wahl P,
Ziegler R, Bierhaus A and Nawroth PP (1999) Peripheral blood mononuclear cells
isolated from patients with diabetic nephropathy show increased activation of
the oxidative-stress sensitive transcription factor NF-kB. Diabetologia 42
222-232 Hofmann TG,
Hehner SP, Bacher S, Droge W and Schmitz ML (1998) Various glucocorticoids
differ in their ability to induce gene expression, apoptosis and to repress
NF-kB-dependent transcription. FEBS Letters 441 441-446 Hofmann TG and Schmitz LM (2003) The promoter context determines mutual repression or synergism between NF-kB and the glucocorticoid receptor. Biological Chemistry 383 1947-1951 Hofseth LF and Wargovich MJ (2007) Inflammation, cancer, and targets of ginseng. Journal of Nutrition 137 183S-185S Hogan SP, Seidu L, Blanchard C, Groschwitz K, Mishra A, Karow ML, Ahrens R, Artis D, Murphy AJ, Valenzuela DM, Yancopoulos GD and Rothenberg ME (2006) Resistin-like molecule beta regulates innate colonic function: Barrier integrity and inflammation susceptibility. Journal of Allergy and Clinical Immunology 118 257-268 Hogan TH, Nonnemacher MR, Krebs FC, Henderson A and Wigdahl B (2003) HIV-1 Vpr binding to HIV-1 LTR C/EBP cis-acting elements and adjacent regions is sequence-specific. Biomedical Pharmacotherapy 57 41-48 Hohberger L, Wuertz BR, Xie H, Griffin T and Ondrey F (2008) TNF-a drives matrix metalloproteinase-9 in squamous oral carcinogenesis. Laryngoscope in press Hohensinner PJ, Kaun C, Rychli K, Niessner A, Pfaffenberger S, Rega G, de Martin R, Maurer G, Ullrich R, Huber K and Wojta J (2007) Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha VIA NF-kB dependent mechanism. Journal of Thrombosis and Haemostosis 5 2520-2528 Hohler T, Reuss E, Adams P, Bartsch B, Weigmann B, Worns M, Galle PR, Victor A and Neurath MF (2005) A genetic basis for IFN-g production and T-bet expression in humans. Journal of Immunology 175 5457-5462
Hohmann HP,
Brockhaus M, Baeuerle PA, Remy R, Kolbeck R and Van Loon AP (1990) Expression
of the types A and B tumor necrosis factor (TNF) receptors is independently
regulated, and both receptors mediate activation of the transcription factor
NF-kB. TNF a is not needed for induction of a biological effect via TNF
receptors. Journal of Biological Chemistry 265 22409-22417 Hohmann H-P,
Kolbeck R, Remy R and van Loon APGM (1991) Cyclic AMP-independent activation
of transcription factor NF-kB in HL-60 cells by tumor necrosis factors a and
b. Molecular and Cellular Biology 11 2315-2318 Hohmann H-P,
Remy R, Aigner L, Brockhaus M and van Loon APGM (1992) Protein kinases
negatively affect Nuclear Factor-kB activation by tumor necrosis factor-a at
two different stages in promyelocytic HL60 cells. Journal of Biological
Chemistry 267 2065-2072 Hohmann H-P,
Remy R, Scheidereit C and van Loon APGM (1991) Maintenance of NF-kB activity
is dependent on protein synthesis and the continuous presence of external
stimuli. Molecular and Cellular Biology 11 259-266 Hohmann HP, Remy R, Poschl B and van Loon AP (1990) Tumor necrosis factors-alpha and -beta bind to the same two types of tumor necrosis factor receptors and maximally activate the transcription factor NF-kB at low receptor occupancy and within minutes after receptor binding. Journal of Biological Chemistry 265 15183-15138
Hohne M,
Schaerer S, Seifewr M, Feitelson MA, Paul D and Gerlich WH (1990) Malignant
transformation of immortalized transgenic hepatocytes after transfection with
hepatitis B virus DNA. EMBO Journal 9 1137-1145 Hoki Y, Hiraku Y, Ma N, Murata M, Matsumine A, Nagahama M, Shintani K, Uchida A and Kwanishi S (2007) iNOS-dependent DNA damage in patients with malignant fibrous histiocytoma in relation to prognosis. Cancer Science 98 163-168 Hoki Y, Murata M, Kiraku Y, Ma N, Matsumine A, Uchida A adn Kawanishi S (2007) 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer. Oncology Reports 18 1165-1169 Holcomb B, Yip-Schneider MT, Matos JM, Dixon J, Kennard J, Mahomed J, Shanmugam R, Sebolt-Leoppold J and Schmidt CM (2007) Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies. Journal of Gastrointestinal Surgery in press Holcomb B, Yip-Schneider M and Schmidt CM (2008) The role of nuclear factor kappaB in pancreatic cancer and the clinical applications of targeted therapy. Pancrease 36 225-235 Holden NS, Catley MC, Cambridge LM, Barnes PJ and Newton R (2004) ICAM-1 expression is highly NF-kB-dependent in A549 cells. European Journal of Biochemistry 271 785-791 Holden NS, Squires PE, Kaur M, Bland R, Jones CE and Newton R (2008) Phorbol ester-stimulated NF-kB-dependent transcription: Roles for isoforms of novel protein kinase C. Cellular Signaling in press
Holden RJ and
Mooney PA (1999) The p53 paradox in the pathogenesis of tumor progression. Medical
Hypotheses 52 483-485 Holding CA, Findlay DM, Stamenkov R, Neale SD, Lucas H, Dharmapatni AS, Callary SA, Shrestha KR, Atikins GJ, Howie DW and Haynes DR (2006) The correlation of RANK, RANKL and TNFalpha expression with bone loss volume and polyethylene wear debris around hip implants. Biomaterials 27 5212-5219 Holdorf AD, Kanagawa O and Shaw AS (2000) CD28 and T cell co-stimulation. Reviews in Immunogenetics 2 175-184 Holland P,
Willis C, Kanaly S, Glaccum M, Warren A, Charrier K, Murison J, Derry J, Virca
G, Bird T, Peschon J (2002) RIP4 is an ankyrin repeat-containing kinase
essential for keratinocyte differentiation. Current Biology 12 1424 Hollander J,
Bejma J, Ookawara T, Ohno H and Ji LL (2000) Superoxide dismutase gene
expression in skeletal muscle: fiber-specific effect of age. Mechanisms of Ageing
and Development
116 33-45 Hollander J, Fiebig R, Gore M, Ookawara T, Ohno H and Ji LL (2001) Superoxide dismutase gene expression is activated by a single bout of exercise in rat skeletal muscle. Pflugers Archives 442 426-434 Hollenbach E, Neumann M, Vieth M, Roessner A, Malfertheiner P and Naumann M (2004) Inhibition of p38 MAP kinase- and RICK/NF-kB-signaling suppresses inflammatory bowel disease. FASEB Journal 18 1550-1552 Hollenbach E, Vieth M, Roessner A, Neumann M, Malfertheiner P and Naumann M (2005) Inhibition of RICK/nuclear factor-kB- and p38 signaling attenuates the inflammatory response in a murine model of Crohn's disease. Journal of Biological Chemistry 280 14981-14988 Holler E, Rogler G, Herfarth H, Brenmoehl J, Wild PJ, Hahn J, Eissner G, Schoelmerich J and Andreesen R (2004) Both, donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation. Blood 104 889-894 Hollmann AC, Gong Q and Owens T (2002) CD40-mediated apoptosis in murine B-lymphoma lines containing mutated p53. Experimental Cell Research 280 201-211 Holloway AF, Rao S, Chen X and Shannon MF (2003) Changes in chromatin accessibility across the GM-CSF promoter upon T cell activation are dependent on nuclear factor kB proteins. Journal of Experimental Medicine 197 413-423 Holloway G and Coulson BS (2006) Rotavirus activates JNK and p38 signaling pathways in intestinal cells leading to AP-1-driven transcriptional responses and enhanced virus replication. Journal of Virology 80 10624-10633 Holloway JN, Murthy S and El-Ashry D (2004) A cytoplasmic substrate of MAPK is responsible for ER{alpha} downregulation in breast cancer cells: the role of NFkB. Molecular Endocrinology 18 1396-1410 Holloway WR, Collier FM, Aitken CJ, Myers DE, Hodge JM, Malakellis M, Gough TJ, Collier GR and Nicholson GC (2002) Leptin inhibits osteoclast generation. Journal of Bone and Mineral Research 17 200-209 Holm GH, Zurney J, Tumilasci V, Leveille S, Danthi P, Hiscott J, Sherry B and Dermody TS (2007) RIG-I and IPS-1 augment proapoptotic responses following mammalian reovirus infection via IRF-3. Journal of Biological Chemistry in press Holman C (2006) Clearing a path though the patent thicket. Cell 125 629-633
Holmberg C,
Katz S, Lerdrup M, Herdegen T, Jaattela M, Aronheim A and Kallunki T (2002) A
novel specific role for I-kB kinase complex-associated protein in cytosolic
stress signaling. Journal of Biological Chemistry 277 31918-31928 Holmen C, Elsheikh E, Christensson M, Liu J, Johansson AS, Qureshi AT, Jalkanen S and Sumitran-Holgersson S (2007) Anti endothelial cell autoantibodies selectively activate SAPK/JNK signalling in Wegener's Granulomatosis. Journal of the American Society of Nephrology 18 2497-2508 Holmes D, Knudsen G, Mackey-Cushman S and Su L (2007) FoxP3 enhances HIV-1 gene expression by modulating NF-kB occupancy at the long terminal repeat in human T cells. Journal of Biological Chemistry 282 15973-15980 Holmes T, O'Brien TA, Knight R, Lindeman R, Symonds G and Donikov A (2008) The role of glycogen synthase kinase-3beta in normal haematopoiesis, angiogenesis and leukaemia. Current Medicinal Chemistry 15 1493-1499 Holmes-McNary
M (2002) Nuclear factor kB signaling in catabolic disorders. Curr Opin Clin
Nutr Metab Care 5 255-263 Holmes-McNary M and Baldwin AS Jr (2000) Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkB kinase. Cancer Research 60 3477-3483 Holmes-McNary MQ, Baldwin AS Jr and Zeisel SH (2001) Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kB. Journal of Biological Chemistry 276 41197-41204 Holschermann H, Durfeld F, Maus U, Bierhaus A, Heidinger K, Lohmeyer J, Nawroth PP, Tillmanns H and Haberbosch W (1996) Cyclosporine a inhibits tissue factor expression in monocytes/macrophages. Blood 88 3837-3845 Holschermann H, Kohl O, Maus U, Durfeld F, Bierhaus A, Nawroth PP, Lohmeyer J, Tillmanns H and Haberbosch W (1997) Cyclosporin A inhibits monocyte tissue factor activation in cardiac transplant recipients. Circulation 96 4232-4238 Holschermann H, Rascher C, Oelschlager C, Stapfer G, Langenstein A, Staubitz A, Maus U, Tillmanns H, Bang H and Haberbosch W (2001) Opposite regulation of tissue factor expression by calcineurin in monocytes and endothelial cells. Journal of Immunology 166 7112-7120 Holschermann H, Schuster D, Parviz B, Haberbosch W, Tillmanns H and Muth H (2005) Statins prevent NF-kB transactivation independently of the IKK-pathway in human endothelial cells. Atherosclerosis in press Holschermann H, Terhalle HM, Zakel U, Maus U, Parviz B, Tillmanns H and Haberbosch W (1999) Monocyte tissue factor expression is enhanced in women who smoke and use oral contraceptives. Thromb Haemost 82 1614-1620 Holt RU, Baykov V, Ro TB, Brabrand S, Waage A, Sundan A and Borset M (2005) Human myeloma cells adhere to fibronectin in response to hepatocyte growth factor. Haematologica 90 479-488 Holtick U, Vockerodt M, Pinkert D, Schoof N, Sturzenhofecker B, Kussebi N, Lauber K, Wesselborg S, Loffler D, Horn F, Trumper L and Kube D (2005) STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis. Leukemia 19 936-944 Holtje M, Hofmann F, Lux R, Veh RW, Just I and Ahert-Hilger G (2008) Glutamate uptake and release by astrocytes is enhanced by clostridium botulinum C3 protein. Journal of Biological Chemistry in press Holtmann H, Enninga J, Kalble S, Thiefes A, Dorrie A, Broemer M, Winzen R, Wilhelm A, Ninomiya-Tsuji J, Matsumoto K, Resch K and Kracht M (2001) The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation. Journal of Biological Chemistry 276 3508-3516 Holtmann H, Winzen R, Holland P, Eickemeier S, Hoffmann E, Wallach D, Malinin NL, Cooper JA, Resch K and Kracht M (1999) Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Molecular and Cellular Biology 19 6742-6753 Holvoet S, Vincent C, Schmitt D and Serres M (2003) The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-alpha in human keratinocytes. Experimental Cell Research 290 108-119
Holzfeind P, Merscha Homaidan FR, Chakroun I and El-Sabban ME (2003) Regulation of nuclear factor-kB in intestinal epithelial cells in a cell model of inflammation. Mediators Inflamm 12 277-283 Homhual S, Zhang HJ, Bunyapraphatsara N, Kondratyuk TP, Santarsiero BD, Mesecar AD, Herunsalee A, Chaukul W, Pezzuto JM and Fong HH (2006) Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza. Planta Medica 72 255-260 Homig-Holzel C, Hojer C, Rastelli J, Casola S, Strobl LJ, Muller W, Quintanilla-Martinez L, Gewies A, Ruland J, Rajewsky K and Zimber-Strobl U (2008) Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kB pathway and promotes lymphomagenesis. Journal of Experimental Medicine in press Homma Y, Cao S, Shi X and Ma X (2007) The Th2 transcription factor c-Maf inhibits IL-12p35 gene expression in activated macrophages by targeting NF-kB nuclear translocation. Journal of Interferon Cytokine Research 27 799-808 Honda N, Yagi K, Ding GR and Miyakoshi J (2002) Radiosensitization by
overexpression of the nonphosphorylation form of IkB-a in human glioma cells.
Journal of Radiation Research 43 283-292 Honda Y, Yamagiwa S, Matsuda Y, Takamura M, Ichida T and Aoyagi Y (2007) Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis. Journal of Hepatology in press Hong CY, Park JH, Ahn RS, Im SY, Choi HS, Soh J, Mellon SH and Lee K (2004)
Molecular mechanism of suppression of testicular steroidogenesis by
proinflammatory cytokine tumor necrosis factor alpha. Molecular and Cellular
Biology 24 2593-2604 Hong GS and Jung YK (2002) Caspase recruitment domain (CARD) as a bi-functional switch of caspase regulation and NF-kB signals. Journal of Biochemistry and Molecular Biology 35 19-23 Hong H, Kitaura J, Xiao W, Horejsi V, Ra C, Lowell CA, Kawakami Y and Kawakami T (2007) The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn. Blood in press Hong HJ, Wu CC, Yen MH (1998) Pyrrolidine dithiocarbamate improves the septic shock syndromes in spontaneously hypertensive rats. Clinical and Experimental Pharmacology and Physiology 25 600-606 Hong J, Leung E, Fraser AG, Merriman TR, Vishnu P and Krissansen GW (2007) Polymorphisms in NFKBIA and ICAM-1 genes in New Zealand Caucasian Crohn's disease patients. Journal of Gastroenterology and Hepatology in press Hong J, Nakano Y, Yokomakura A, Ishihara K, Kim S, Kang YS and Ohuchi K (2006) Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors Bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells. Journal of Pharmacology and Experimental Therapeutics 319 672-681 Hong J, Sang S, Park HJ, Kwon SJ, Suh N, Huang MT, Ho CT and Yang CS (2006) Modulation of arachidonic acid metabolism and nitric oxide synthesis by garcinol and its derivatives. Carcinogenesis 27 278-286 Hong J, Yokomakura A, Nakano Y, Ban HS, Ishihara K, Ahn JW, Zee O and Ohuchi K (2004) Induction of nitric oxide production by the cytostatic macrolide apicularen A and possible role of nitric oxide in apicularen A-induced apoptosis in RAW 264.7 cells. Journal of Pharmacology and Experimental Therapy 312 968-977 Hong
JH, Choi
JH, Oh SR, Lee HK, Park JH, Lee KY, Kim JJ, Jeong TS and Oh GT (2001)
Inhibition of cytokine-induced vascular cell adhesion molecule-1 expression;
possible mechanism for anti-atherogenic effect of Agastache rugosa. FEBS
Letters 495 142-147 Hong JJ,
Jeong TS, Choi JH, Park JH, Lee KY, Seo YJ, Oh SR and Oh GT (2001) Hematein
inhibits tumor necrotic factor-alpha-induced vascular cell adhesion molecule-1
and NF-kB-dependent gene expression in human vascular endothelial cells.
Biochemical and Biophysical Research Communications 281 1127-1133 Hong JR, Guan BJ, Her GM, Evensen O, Santi N and Wu JL (2008) Aquatic birnavirus infection activates the transcription factor NF-kB via tyrosine kinase signalling leading to cell death. Journal of Fish Disease 31 451-460 Hong JT, Kim
EJ, Ahn KS, Jung KM, Yun YP, Park YK and Lee SH (2001) Inhibitory effect of
glycolic acid on ultraviolet-induced skin tumorigenesis in SKH-1 hairless mice
and its mechanism of action. Molecular Carcinogenesis 31 152-160 Hong JT, Lee MK, Park KS, Jung KM, Lee RD, Jung HK, Park KL, Yang KJ and Chung YS (2002) Inhibitory effect of peroxisome proliferator-activated receptor gamma agonist on ochratoxin A-induced cytotoxicity and activation of transcription factors in cultured rat embryonic midbrain cells. Journal of Toxicology and Environmental Health A 65 407-418 Hong JW, Allen CE and Wu LC (2003) Inhibition of NF-kB by ZAS3, a zinc-finger protein that also binds to the kB motif. Proceedings of the National Academy of Sciences USA 100 12301-12306 Hong KH, Yoo SA, Kang SS, Choi JJ, Kim WU and Cho CS (2006) Hypoxia induces expression of connective tissue growth factor in scleroderma skin fibroblasts. Clinical and Experimental Immunology 146 362-370
Hong Q, Hsu LJ, Schultz L, Pratt N, Mattison J and Chang NS (2007) Zfra
affects TNF-mediated cell death by interacting with death domain protein TRADD
and negatively regulates the activation of NF-kB, JNK1, p53 and WOX1 during
stress response. Hong S, Brass A, Seman M, Haag F, Koch-Nolte F and Dubyak GR (2007) Lipopolysaccharide, IFN-gamma, and IFN-beta induce expression of the thiol-sensitive ART2.1 Ecto-ADP-ribosyltransferase in murine macrophages. Journal of Immunology 179 6215-6227 Hong S, Lee C,a dn Kim SJ (2007) Smad7 sensitizes tumor necrosis factor induced apoptosis through the inhibition of antiapoptotic gene expression by suppressing activation of the nuclear factor-kB pathway. Cancer Research 67 9577-9583 Hong S, Lee JE, Kim CY and Seong GJ (2007) Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line. BMC Neuroscience in press Hong S, Lim S, Li AG, Lee C, Lee YS, Lee EK, Park SH, Wang XJ and Kim SJ (2007) Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2. Nature Immunology 8 504-513 Hong S, Wang LC, Gao X, Kuo YL, Liu B, Merling R, Kung HJ, Shih HM and Giam CZ (2007) Heptad repeats regulate protein phosphatase 2A recruitment to IkB kinase g/NF-kB essential modulator and are targeted by human T-lymphotropic virus type 1 Tax. Journal of Biological Chemistry 282 12119-12126 Hong SH, Seo SH, Lee JH and Choi BT (2004) The aqueous extract from Artemisia capillaris Thunb. inhibits lipopolysaccharide-induced inflammatory response through preventing NF-kappaB activation in human hepatoma cell line and rat liver. International Journal of Molecular Medicine 13 717-720 Hong SS, Lee SA, Han XH, Jin HZ, Lee JH, Lee D, Lee JJ, Hong JY, Kim Y, Ro JS and Hwang BY (2007) Kaurane diterpenoids from Isodon excisus inhibit LPS-induced NF-kB activation and NO production in macrophage RAW264.7 cells. Journal of Natural Products in press Hong SY, Yoon WH, Park JH, Kang SG, Ahn JH and Lee TH (2000) Involvment of two NF-kB binding
elements in tumor necrosis factor a-, CD40-, and Epstein-Barr virus
latent membrane protein 1-mediated induction of the cellular inhibitor of
apoptosis protein 2 gene. Journal of Biological Chemistry 275 18022-18028 Hong X, Xu L,
Li X, Zhai Z and Shu H (2001) CSN3 interacts with IKKg and inhibits TNF- but
not IL-1-induced NF-kB activation. FEBS Letters 499 133-136 Hong Y, Holley-Guthrie E and Kenney S (1997) The bZip dimerization domain of the Epstein-Barr virus BZLF1 (Z) protein mediates lymphoid-specific negative regulation. Virology 229 36-48 Hong YH, Peng HB, La Fata V and Liao JK (1997) Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulating factor by TGF-beta1. Journal of Immunology 159 2418-2423 Hong Z, Jiang Z, Liangxi W, Guofu D, Ping L, Yongling L, Wendong P and Minghai W (2004) Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release. International Immunopharmacology 4 223-234 Honma K, Udono H, Kohno T, Yamamoto K, Ogawa A, Takemori T, Kumatori A, Suzuki S, Matsuyama T and Yi K (2005) Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS. Proceedings of the National Academy of Sciences USA in press Honore PM and Matson JR (2004) Extracorporeal removal for sepsis: Acting at the tissue level--the beginning of a new era for this treatment modality in septic shock. Critical Care Medicine 32 896-897 Hoo RL, Chan KY, Leung FK, Lee LT, Leung PC and Chow BK (2007) Involvement of NF-kB subunit p65 and retinoic acid receptors, RARalpha and RXRalpha, in transcriptional regulation of the human GnRH II gene. FEBS Journal in press Hooft van Huijsduijnen RA (1992) PCR-generated probes for the study of DNA-protein interactions. Biotechniques 12 830-832
Hooft van
Huijsduijnen R, Pescini R and DeLamarter JF (1993) Two distinct NF-kB
complexes differing in their larger subunit bind the E-selectin promoter kB
element. Nucleic Acids Research 21 3711-3717 Hooft van Huijsduijnen R, Whelan J, Pescini R, Becker-Andre M, Schenk AM and DeLamarter JF (1992) A T-cell enhancer cooperates with NF-kB to yield cytokine induction of E-selectin gene transcription in endothelial cells. Journal of Biological Chemistry 267 22385-22391 |