Regulation
of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant
Nacystelyn.
Antonicelli F, Brown D, Parmentier M, Drost EM, Hirani N, Rahman I, Donaldson
K, MacNee
|
References Relevant publications listed by the last name of
the first author. Aarenstrup L, Flindt EN, Otkjaer K,Kirkegaard M, Andersen JS and Kristiansen K (2007) HDAC activity is required for p65/RelA-dependent repression of PPARdelta-mediated transactivation in human keratinocytes. Journal of Investigative Dermatology in press
Aarnisalo P, Palvimo JJ and Janne OA (1998) CREB-binding
protein in androgen receptor-mediated signaling. Proceedings of the National
Academy of Sciences USA 95 2122-2127
Aarnisalo
P, Santti H, Poukka H, Palvimo JJ and Janne OA (1999) Transcription activating
and repressing functions of the androgen receptor are differentially
influenced by mutations in the deoxyribonucleic acid-binding
domain.
Endocrinology 140 3097-3105
Abate
A, Oberle S and Schroder H (1998) Lipopolysaccharide-induced expression of
cyclooxygenase-2 in mouse macrophages is inhibited by chloromethylketones and
a direct inhibitor of NF-kB translocation. Prostaglandins and Other Lipid Mediators
56 277-290 Abate
A, Yang G, Dennery PA, Oberle S and Schroder H (2000) Synergistic inhibition
of cyclooxygenase-2 expression by vitamin E and aspirin. Free Radical Biology
and Medicine
29 1135-1142 Abate DA, Watanabe S and Mocarski ES (2004) Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response. Journal of Virology 78 10995-11006 Abayomi EA, Sissolak G and Jacobs P (2007) Use of novel proteosome inhibitors as a therapeutic strategy in lymphomas current experience and emerging concepts. Transfusion and Apheresis Science 37 85-92 Abbadie
C, Kabrun N, Bouali F, Smardova J, Stéhelin D, Vandenbunder B and Enrietto PJ
(1993) High levels of c-rel
expression are associated with programmed cell death in the developing avian
embryo and in bone marrow cells in vitro. Cell 75 899-912 Abbott DW, Wilkins A, Asara JM and Cantley LC (2004) The Crohn's Disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Current Biology 14 2217-2227 Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA nad Cantley LC (2007) Coordinate regulation of Toll-like Receptor and NOD2 signaling by K63-linked polyubiquitin chains. Molecular and Cellular Biology inpress Abbott
KL, Loss JR 2nd, Robida AM and Murphy TJ (2000) Evidence that Galpha(q)-coupled
receptor-induced interleukin-6 mRNA in vascular smooth muscle cells involves
the nuclear factor of activated T cells. Molecular Pharmacology 58 946-953 Abbott KL, Robida AM, Davis ME, Pavlath GK, Camden JM,
Turner JT and Murphy TJ (2000) Differential regulation of vascular smooth
muscle nuclear factor kB by G alpha q-coupled and cytokine receptors. Journal
of Molecular and Cellular Cardiology 32 391-403 Abboud PA, Lahni PM, Page K, Giuliano Jr JS, Harmon K, Dunsmore KE, Wong HR and Wheeler DW (2008) The role of endogenously produced extracellualr HSP72 in mononuclear cell reprogramming in press Abboushi N, El-Hed A, El-Assaad W, Kozhaya L, El-Sabban ME, Bazarbachi A,
Badreddine R, Bielawska A, Usta J and Dbaibo GS (2004) Ceramide inhibits IL-2
production by preventing protein kinase C-dependent NF-kB activation: possible
role in protein kinase C{theta} regulation. Journal of Immunology 173
3193-3200 Abdallah A, Sato H, Grutters JC, Veeraraghavan S, Lympany PA, Ruven HJ, Van
Den Bosch JM, Wells AU, Du Bois RM and Welsh KI (2003) Inhibitor kB-a (IkB-a)
promoter polymorphisms in UK and Dutch sarcoidosis. Genes & Immunity 4
450-454 Abdel-Latif MM, Kelleher D and Reynolds JV (2008) Potential role of NF-kB in esophageal adenocarcinoma: as an emerging molecular target. Journal of Surgical Research in press Abdel-Latif MM, O'Riordan JM, Ravi N, Kelleher D and Reynolds JV (2005) Activated nuclear factor-kB and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy. Dis Esophagus 18 246-252 Abdel-Latif
MM, O'Riordan J, Windle HJ, Carton E, Ravi N, Kelleher D and
Reynolds JV (2004) NF-kB activation in esophageal adenocarcinoma: relationship
to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy. Annals of Surgery 239 491-500 Abdel-Mageed
AB (2003) NF-kB-dependent gene expression of proinflammatory cytokines in T24
cells: possible role in interstitial cystitis. Urology Research 31 300-305 Abdel-Razzak
Z, Garlatti M, Aggerbeck M and Barouki R (2004) Determination of
interleukin-4-responsive region in the human cytochrome P450 2E1 gene
promoter. Biochemical Pharmacology 68 1371-1381 Abdouh
M, Albert PR, Drobetsky E, Filep JG and Kouassi E (2004) 5-HT(1A)-mediated
promotion of mitogen-activated T and B cell survival and proliferation is
associated with increased translocation of NF-kB to the nucleus. Brain Behav
Immun 18 24-34 Abdulla D, Goralski KB, Garcia Del Busto Cano E and Rneton KW (2005) The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during an LPS-induced model of CNS inflammation. Drug Metabolism and Disposition 33 1521-1531 Abdulla D and Renton KW (2005) beta-Adrenergic receptor modulation of the
LPS-mediated depression in CYP1A activity in astrocytes. Biochemical
Pharmacology 69 741-750 Abe JL (2007) Role of PKCs and NF-kB activation in myocardial inflammation: Enemy or ally? Journal of Molecular and Cellular Cardiology in press Abe K, Whitehead IP, O'Bryan JP and Der CJ (1999) Abe M, Takiguchi Y, Ichimaru S, Tsuchiya K and Wada K (2008) Comparison of the protective effect of N-acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury. Journal of Pharmacological Sciences 106 571-577 Abe M, Takiguchi Y, Ichimaru S, Tsuchiya K and Wada K (2008) Different effect of acute treatment with rosiglitazone on rat myocardial ischemia/reperfusion injury by administration method. European Journal of Pharmacology in press Abe M, Tanaka Y, Saito K, Shirakawa F, Koyama Y, Goto S and Eto S (1997)
Regulation of interleukin (IL)-1beta gene transcription induced by IL-1beta in
rheumatoid synovial fibroblast-like cells, E11, transformed with simian virus
40 large T antigen. Journal of Rheumatology 24 420-429 Aberle H, Bauer A, Stappert J, Kispert A and Kemler R (1997) b-catenin is
a target for the ubiquitin-proteasome pathway. EMBO Journal 16 3797-3804 Abeyama K, Eng W, Jester JV, Vink AA, Edelbaum D, Cockerell CJ,
Bergstresser PR, Takashima A (2000) A role for NF-kB-dependent gene
transactivation in sunburn. Journal of Clinical Investigation 105 1751-1759 Abiru S, Nakao K, Ichikawa T, Migita K, Shigeno M, Sakamoto M, Ishikawa H,
Hamasaki K, Nakata K and Eguchi K (2002) Aspirin and NS-398 inhibit hepatocyte
growth factor-induced invasiveness of human hepatoma cells. Hepatology 35
1117-1124 Abou-Merhi
R, Khoriaty R, Arnoult D, El Hajj H, Dbouk H, Munier S, El-Sabban ME, Hermine
O, Gessain A, de The H, Mahieux R and Bazarbachi A (2007) PS-341 or a
combination of arsenic trioxide and interferon-alpha inhibit growth and induce
caspase-dependent apoptosis in KSHV/HHV-8-infected primary effusion lymphoma
cells. Abraham C and Cho JH (2006) Functional consequences of NOD2 (CARD15) mutations. Inflammatory Bowel Disease 12 641-650 Abraham
DJ, Shiwen X, Black CM, Sa S, Xu Y and Leask A (2000) Tumor necrosis factor
alpha suppresses the induction of connective tissue growth factor by
transforming growth factor-beta in normal and scleroderma fibroblasts. Journal
of Biological Chemistry 275 15220-15225 Abraham E (2000) NF-kB activation. Critical Care Medicine
28
N100-N104 Abraham E, Arcaroli J
and Shenkar R (2001) Activation of extracellular signal-regulated kinases,
NF-kB, and cyclic adenosine 5'-monophosphate response element-binding protein
in lung neutrophils occurs by differing mechanisms after hemorrhage or
endotoxemia. Journal of Immunology 166 522-530 Abraham S, Yaddanapudi K, Thomas S, Damodaran A, Ramireddy B and Manjunath R (2008) Nonclassical MHC-I and Japanese encephalitis virus infection: induction of H-2Q4, H-2T23 and H-2T10. Virus Research in press Abrahams VM, Aldo PB, Murphy SP, Visintin I, Koga K, WIlson G, Romero R, Sharma S and Mor G (2008) TLR6 modulates first trimester trophoblast responses to peptidoglycan. Journal of Immunology 180 6035-6043 Abrams CC, Chapman DA, Silk R, Liverani E and Dixon LK (2008) Domains involved in calcineurin phosphatase inhibition and nuclear localisation in the African swine fever virus A238L protein. Virology in press Abramson J, Licht A and Pecht I (2006) Selective inhibition of the FcvarepsilonRI-induced de novo synthesis of mediators by an inhibitory receptor. EMBO Journal 25 323-334 Abrantes EF, Pires EG, Carvalho AF, Costa FF, Savino W and Reis LF (2003) Identification, structural characterization, and tissue distribution of Tsg-5: a new TNF-stimulated gene. Genes and Immunity 4 298-311 Abreu MT, Arnold ET,
Thomas LS, Gonsky R, Zhou Y, Hu B and Arditi M (2002) TLR4 and MD-2 expression
is regulated by immune-mediated signals in human intestinal epithelial cells.
Journal of Biological Chemistry 277 20431-20437 Abril
E, Mendez RE, Garcia A, Serrano A, Cabrera T, Garrido F and Ruiz-Cabello F
(1996) Characterization of a gastric tumor cell line defective in MHC class I
inducibility by both alpha- and gamma-interferon. Tissue Antigens 47 391-398 Abruzzese RV, Godin D, Burcin M, Mehta V, French M, Li Y, O'Malley BW and
Nordstrom JL (1999) Ligand-dependent regulation of plasmid-based transgene
expression in vivo. Human Gene Therapy 10 1499-1507 Abshagen K, Eipel C, Kalff JC, Menger MD and Vollmar B (2007) Loss of NF-kB activation in Kupffer cell-depleted mice impairs liver regeneration after partial hepatectomy. American Journal of Physiology: Gastrointestinal Liver Physiology in press Abu-Amer
Y (2001) IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition
of NF-kB. Journal of Clinical Investigation 107 1375-1385 Abu-Amer Y, Darwech I and Otero J (2008) Role of the NF-kB axis in immune modulation of osteoclasts and bone loss. Autoimmunity 41 204-211 Abu-Amer
Y, Erdmann J, Alexopoulou L, Kollias G, Ross FP and Teitelbaum SL (2000) Tumor
necrosis factor receptors types 1 and 2 differentially regulate
osteoclastogenesis. Journal of Biological Chemistry 275 27307-27310 Abu-Amer
Y, Ross FP, McHugh KP, Livolsi A, Peyron J-F and Teitelbaum SL (1997) Tumor
necrosis factor-a activation of nuclear transcription factor-kB in marrow
macrophages is mediated by c-Src tyrosine phosphorylation of IkBa. Journal of
Biological Chemistry 273 29417-29423 Abu-Zant A, Jones S, Asare R, Suttles J, Price C, Graham J and Kwaik YA (2007) Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophila. Cellular Microbiology 9 246-264 Abujamra AL, Spanjaard RA, AKinsheye I, Zhao X, Faller DV and Ghosh SK (2005) Leukemia virus long terminal repeat activates NFkB pathway by a TLR3-dependent mechanism. Virology 345 390-403 Acaria
L, Gonzalez B and Castellano B (1998) Stat3 and NF-kB glial expression after
excitotoxic damage to the postnatal brain. Neuroreport 9 2869-2873 Acarin L, Gonzalez B and Castellano B (2000) STAT3 and
NF-kB activation precedes glial reactivity in the excitotoxically injured
young cortex but not in the corresponding distal thalamic nuclei. Journal of Neuropathology
and Experimental Neurology 59 151-163 Acarin
L, Gonzalez B, Castellano B (2001) Acharyya S and Guttridge DC (2007) Cancer cachexia signaling pathways continue to emerge yet much still points to the proteasome. Clinical Cancer Research 13 1356-1361 Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, Baldwin AS and Guttridge DC (2007) Interplay of IKK/NF-kB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. Journal of Clinical Investigation 117 889-901 Achiron A, Feldman A, Mandel M and Gurevich M (2007) Impaired expression of peripheral blood apoptotic-related gene transcripts in acute multiple sclerosis relapse. Annals of the New York Academy of Sciences 1107 155-167 Ackerman H, Udalova I, Hull J and Kwiatkowski D (2002) Evolution of a polymorphic regulatory element in interferon-gamma through transposition and mutation. Molecular Biology and Evolution 19 884-890
Ackerman IV WE, Rovin BH and Kniss DA (2004) Epidermal growth factor and
interleukin-1b utilize divergent signaling pathways to synergistically
upregulate cyclooxygenase-2 gene expression in human amnion-derived WISH
cells. Biology of Reproduction 71 2079-2086 Ackerman IV WE, Zhang XL, Rovin BH and Kniss DA (2005) Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkB signal disruption in human WISH and amnion cells. Biology of Reproduction 73 527-535
Ackermann LW and Denning GM (2004) Nuclear factor-kB contributes to
interleukin-4- and interferon-dependent polymeric immunoglobulin receptor
expression in human intestinal epithelial cells. Immunology 111 75-85
Acquaah-Mensah GK, Kehrer JP and Leslie SW (2002) In utero
ethanol suppresses
cerebellar activator protein-1 and nuclear factor-kB transcriptional
activation in a rat fetal alcohol syndrome model. Journal of Pharmacology
and Experimental Therapy 301
277-283
Acquaviva R, Campisi A, Raciti G, Avola R, Barcellona ML, Vanella A and Li Volti G
(2005) Propofol
inhibits caspase-3 in astroglial cells: role of heme oxygenase-1. Current
Neurovascular Research 2 141-148 Adachi
O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, Sakagami M, Nakanishi K and
Akira S (1998) Targeted disruption of the MyD88 gene results in loss of IL-1-
and IL-18-mediated function. Immunity 9 143-150 Adam D, Kessler U and Kronke M (1995) Cross-linking of the p55 tumor necrosis
factor receptor cytoplasmic domain by a dimeric ligand induces nuclear
factor-kB and mediates cell death. Journal of Biological Chemistry 270
17482-17487 Adam E, Hansen KK, Astudillo Fernandez O, Coulon L, Bex F, Duhant X, Jaumotte E, Hollenberg MD and Jacquet A (2005) The house dust mite allergen DER P 1, unlike DER P 3, stimulates the expression of IL-8 in human airway epithelial cells via a proteinase-activated receptor -2 (PAR2) independent mechanism. Journal of Biological Chemistry 691 6910-6923 Adam
E, Quivy V, Bex F, Chariot A, Collette Y, Vanhulle C, Schoonbroodt S, Goffin
V, Nguyen TL-A, Gloire G, Carrard G, Friguet B, de Launoit Y, Burny A, Bours V,
Piette J and Van Lint C (2003) Potentiation of tumor necrosis factor-induced
NF-kB activation by deacetylase inhibitors is associated with a delayed
cytoplasmic reappearance of IkBa. Molecular and Cellular Biology 23 6200-6209 Adami C, Bianchi R, Pula G and Donato R (2004) S100B-stimulated NO production
by BV-2 microglia is independent of RAGE transducing activity but dependent on
RAGE extracellular domain. Biochimica et Biophysica Acta 1742 169-177 Adams AB, Williams MA, Jones TR, Shirasugi N, Durham MM, Kaech SM, Wherry EJ,
Onami T, Lanier JG, Kokko KE, Pearson TC, Ahmed R and Larsen CP (2003)
Heterologous immunity provides a potent barrier to transplantation tolerance.
Journal of Clinical Investigation 111 1887-1895 Adams
CC and Workman JL (1995) Binding of disparate transcriptional activators to
nucleosomal DNA is inherently cooperative. Molecular and Cellular Biology 15
1405-1421 Adams DS, Nathans R, Pero SC, Sen A and Wakshull E
(2000) Activation of a rel-A/CEBP-beta-related transcription factor heteromer
by PGG-glucan in a murine monocytic cell line. Journal of Cellular Biochemistry 77 221-233 Adams
DS, Pero SC, Petro JB, Nathans R, Mackin WM and Wakshull E (1997) PGG-Glucan
activates NF-kB-like and NF-IL-6-like transcription factor complexes in a
murine monocytic cell line. Journal of Leukocyte Biology 62 865-873 Adams J (2004) The proteasome: a suitable antineoplastic target. Nature Reviews Cancer 4 349-360 Adams
J (2004) The development of proteasome inhibitors as anticancer drugs.
Cancer Cell 5 417-421 Adams V, Nehrhoff B, Spate U, Linke A, Schulze PC, Baur A, Gielen S, Hambrecht
R and Schuler G (2002) Induction of iNOS expression in skeletal muscle by
IL-1beta and NFkB activation: an in vitro and in vivo study. Cardiovascular
Research 54 95-104 Adcock IM (1997) Transcription factors as activators of gene transcription:
AP-1 and NF-kB. Monaldi Arch Chest Dis 52 178-186 Adcock IM, Cosio B, Tsaprouni L, Barnes PJ and Ito K (2005) Redox regulation
of histone deacetylases and glucocorticoid-mediated inhibition of the
inflammatory response. Antioxidants & Redox Signaling 7 144-152 Adcock IM, Lane SJ, Brown CR, Lee TH and Barnes PJ (1995) Abnormal
glucocorticoid receptor-activator protein 1 interaction in steroid-resistant
asthma. Journal of Experimental Medicine 182 1951-1958 Addya S, Shiroto K, Turoczi T, Zhan L, Kaga S, Fukuda S, Surrey S, Duan LJ, Fong GH, Yamamoto F and Maulik N (2005) Ischemic preconditioning-mediated cardioprotection is disrupted in heterozygous Flt-1 (VEGFR-1) knockout mice. Journal of Molecular and Cellular Cardiology 38 345-351 Adelson ME, Martinand-Mari C, Iacono KT, Muto NF and Suhadolnik RJ (1999)
Inhibition of human immunodeficiency virus (HIV-1) replication in SupT1 cells
transduced with an HIV-1 LTR-driven PKR cDNA construct. European Journal of
Biochemistry 264 806-815 Adhikari N, Charles N, Lehmann U and Hall JL (2006) Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury. Current Atherosclerosis Reports 8 252-260 Adhirkari A, Xu M and Chen ZJ (2007) Ubiquitin-mediated activation of TAK1 and IKK. Oncogene. 26 3214-3226
Adib-Conquy M, Adrie C, Moine P, Asehnoune K, Fitting C, Pinsky MR, Dhainaut
JF and Cavaillon JM (2000) NF-kB expression in mononuclear cells of patients with
sepsis resembles that observed in lipopolysaccharide tolerance. American Journal
of Respiratory and Critical Care Medicine 162 1877-1883 Adib-Conquy M and Cavaillon JM (2002) IFNg and GM-CSF
prevent endotoxin tolerance in human monocytes by promoting IRAK expression
and its association to MyD88, and not by modulating TLR4 expression. Journal
of Biological Chemistry 277 27927-27934 Adib-Conquy
M, Petit AF, Marie C, Fitting C and Cavaillon JM (1999) Paradoxical priming
effects of IL-10 on cytokine production. International Immunology 11 689-698 Adler V and Kraft AS (1995) Regulation of AP-3 enhancer activity during
hematopoietic differentiation. Journal of Cell Physiology 164 26-34 Adolph KW, Liska DJ and Bornstein P (1997) Analysis of the promoter and transcription start sites of the human thrombospondin 2 gene (THBS2). Gene 193 5-11 Adorini L (2005) Intervention in autoimmunity: The potential of vitamin D receptor agonists. Cellular Immunology 233 115-124 Adorini L, Penna G, Giarratana N, Roncari A, Amuchastegui S, Daniel KC and
Uskokovic M (2004) Dendritic cells as key targets for immunomodulation by
Vitamin D receptor ligands. Journal of Steroid Biochemistry and Molecular
Biology 89-90 437-441 Adriaenssens E, Mougel A, Goormachtigh G, Loing E, Fafeur V, Auriault C and
Coll J (2004) A novel dominant-negative mutant form of Epstein-Barr virus
latent membrane protein-1 (LMP1) selectively and differentially impairs LMP1
and TNF signaling pathways. Oncogene 23 2681-2693 Adzic M, Niciforovic A, Vucic V, Neskovic-Konstantinovic Z, Spasic SD, Jones DR, Radjcic MB and Spasic MB (2006) Systemic NF-kB activation in blood cells of breast cancer patients. Redox Reports 11 39-44 Adzic M, Niciforovic A, Zaric B, Neskovic-Konstantinovic Z, Spasic SD, Jones DR, and Radjcic MB (2008) Cell culture conditions potentiate differences in the response to ionising radiation of peripheral blood leukocytes isolated from breast cancer patients and healthy subjects. Redox Reports 13 17-22 Aeberli D, Yang Y, Mansell A, Santos L, Leech M and Morand EF (2006) Endogenous macrophage migration inhibitory factor modulates glucocorticoid sensitivity in macrophages via effects on MAP kinase phosphatase-1 and p38 MAP kinase. FEBS Letters 580 974-981 Afaq F, Ahmad N and Mukhtar H (2003) Suppression of UVB-induced
phosphorylation of mitogen-activated protein kinases and nuclear factor kB by
green tea polyphenol in SKH-1 hairless mice. Oncogene 22 9254-9264 Afford SC, Ahmed-Choudhury
J, Randhawa S, Russell C, Youster J, Crosby HA,
Eliopoulos A, Hubscher SG,
Young LS and Adams DH (2001) CD40 activation-induced, Fas-dependent apoptosis
and NF-kB/AP-1 signaling in human intrahepatic biliary epithelial cells. FASEB
Journal 15 2345-2354 Afonso PV, Ozden S, Prevost MC, Schmitt C, Seilhean D, Weksler B, Couraud PO, Gessain A, Romero IA and Ceccaldi PE (2007) Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization. Journal of Immunology 179 2576-2583 Aga M, Johnson CJ, Hart
AP, Guadarrama AG, Suresh M, Svaren J, Bertics PJ and Darien BJ (2002)
Modulation of monocyte signaling and pore formation in response to agonists of
the nucleotidereceptor P2X(7). Journal of Leukocyte Biology 72 222-232 Agaisse H, Petersen UM, Boutros M, Mathey-Prevot B and Perrimon N (2003) Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Developmental Cell 5 441-450 Agami R (2007) All roads lead to IKKepsilon. Cell 129 1043-1045 Agapova OA, Kaufman PL and Hernandez MR (2006) Androgen receptor and NFkB expression in human normal and glaucomatous optic nerve head astrocytes in vitro and in experimental glaucoma. Experimental Eye Research 82 1053-1059 Agarwal A, Das K, Lerner N, Sathe S, Cicek M, Casey G and Sizemore N (2004) The AKT/IkB kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kB and beta-catenin. Oncogene 24 1021-1031 Agarwal C, Dhanalakshmi S, Singh RP and Agarwal R (2003) Inositol
hexaphosphate inhibits constitutive activation of NF-kB in
androgen-independent human prostate carcinoma DU145 cells. Anticancer Research
23 3855-3861 Aggarwal AK (1995) A gripping end to NF-kB. Nature Structural Biology 2
184-186 Aggarwal BB (2007) Nuclear factor-kB: a transcription factor for all seasons. Expert Opinion on Therapeutic Targets 11 109-110 Aggarwal
BB, Bhardwaj A, Aggarwal RS, Seeram NP, Shishodia S and Takada Y (2004) Role
of resveratrol in prevention and therapy of cancer: preclinical and clinical
studies. Anticancer Research 24 2783-2840 Aggarwal BB and Higuchi M (1997) Role of ceramide in tumour necrosis factor-mediated apoptosis and nuclear factor-kB activation. Biochemical Society Transactions 25 1166-1171 Aggarwal BB and Ichikawa H (2005) Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. Cell Cycle 4 1201-1215
Aggarwal BB, Ichikawa H, Garodia P, Weerasinghe P, Sethi G, Bhatt ED, Pandey
MK, Shishodia S and Nair MG (2006) From traditional Ayurvedic medicine to
modern medicine: identification of therapeutic targets for suppression of
inflammation and cancer. Aggarwal BB, Kunnumakkara AB, Harikumar KB, Tharakan ST, Sung B and Anand P (2008) Potential of spice-derived phytochemicals for cancer prevention. Planta Medica in press Aggarwal BB and Shishodia S (2004) Suppression of the nuclear factor-kB activation pathway by spice-derived phytochemicals: reasoning for seasoning. Annals of the New York Academy of Sciences 1030 434-441 Aggarwal BB and Shishodia S (2006) Molecular targets of dietary agents for prevention and therapy of cancer. Biochemical Pharmacology 71 1397-1421 Aggarwal
BB, Shishodia S, Ashikawa K and Bharti AC (2002) The role of TNF and
its family members in inflammation and cancer: lessons from gene deletion.
Current Drug Targets of Inflammation and Allergy 1 327-341 Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE and
Price JE (2005) Curcumin suppresses the paclitaxel-induced nuclear factor-kB
pathway in breast cancer cells and inhibits lung metastasis of human breast
cancer in nude mice. Clinical Cancer Research 11 7490-7498 Aggarwal BB, Takada Y and Oommen OV (2004) From chemoprevention to
chemotherapy: common targets and common goals. Expert Opinion on Investigational Drugs 13
1327-1338 Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S and Aggarwal BB (2006) Curcumin (diferuloylmethane) downregulates expression of cell proliferation, antiapoptotic and metastatic gene products through suppression of IkBa kinase and AKT activation. Molecular Pharmacology 69 195-201 Aggarwal S, Takada Y, Mhashilkar AM, Sieger K, Chada S and
Aggarwal BB (2004) Melanoma differentiation-associated gene-7/IL-24 gene
enhances NF-kB activation and suppresses apoptosis induced by TNF. Journal of
Immunology 173 4368-4376 Aghai ZH, Kode A, Saslow JG, Nakhala T, Farhath S, Stahl GE, Eydelman R, Strande L, Leone P and Rahman I (2007) Azithromycin suppresses activation of nuclear factor-kB and synthesis of pro-inflammatory cytokines in tracheal aspirate cells From premature infants. Pediatric Research in press Aghai ZH, Kumar S, Farhath S, Kumar MA, Saslow J, Nakhla T, Eydelman R, Strande L, Stahl G, Hewitt C, Nesin M and Rahman I (2005) Dexamethasone suppresses expression of nuclear factor-kB in the cells of tracheobronchial lavage fluid in premature neonates with respiratory distress. Pediatrics Research 59 811-815 Aghajanian C (2004) Clinical update: novel targets in gynecologic malignancies. Seminars in Oncology 31 22-26
Agou F, Courtois G, Chiaravalli J, Baleux F, Coic YM, Traincard F, Israel A
and Veron M (2004) Inhibition of NF-kB activation by peptides targeting NEMO
oligomerisation. Journal of Biological Chemistry 279 54248-54257 Agou F, Courtois G, Chiaravalli J, Baleux F, Coic YM, Traincard F, Israel A and Veron M (2004) Inhibition of NF-kB activation by peptides targeting NF-kB essential modulator (nemo) oligomerization. Journal of Biological Chemistry 279 54248-54257
Agou F, Traincard F, Vinolo E, Courtois G, Yamaoka S, Israel A and Veron M
(2004) The trimerization domain of NEMO is comprised of the interacting
C-terminal CC2 and LZ coiled-coil subdomains. Journal of Biological Chemistry
279 27861-27869
Agrawal
A, Cha-Molstad H, Samols D and Kushner I (2001) Transactivation of C-reactive
protein by IL-6 requires synergistic interaction of CCAAT/enhancer binding
protein beta (C/EBP beta) and Rel p50. Journal of Immunology 166 2378-2384
Agarwal R, Campbell RC and Warnock DG (2004) Oxidative stress in hypertension
and chronic kidney disease: Role of angiotensin II. Seminars in Nephrology 24
101-114
Aguilera C, Fernandez-Majada V, Ingles-Esteve J, Rodilla V, Bigas A and Espinosa L (2006) Efficient nuclear export of p65-IkBa complexes requires 14-3-3 proteins. Journal of Cell Science 119 3695-3704
Aguilera C, Hoya-Arias R, Haegeman G, Espinosa L and Bigas A (2004)
Recruitment of IkBa to the hes1 promoter is associated with transcriptional
repression. Proceedings of the National Academy of Sciences USA 101 16537-16542 Agusti A, Morla M, Sauleda J, Saus C and Busquets X (2004) NF-kB activation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight. Thorax 59 483-487
Ahmad M, Marui N,
Alexander RW and Medford RM (1995) Cell type-specific transactivation of the
VCAM-1 promoter through an NF-kB enhancer motif. Journal of Biological
Chemistry 270 8976-8983
Ahmad R, Riana D, Meyer C, Kharbanda S and Kufe D (2006) Triterpenoid CDDO-Me blocks the NF-kB pathway by direct inhibition of IKKb on Cys-179. Journal of Biological Chemistry 281 35764-35769
Ahmad R, Raina D, Trivedi V, Ren J, Rajabi H, Kharbanda S and Kufe D (2007) MUC1 oncoprotein activates the IkB kinase beta complex and constitutive NF-kB signalling. Nature Cell Biology in press Ahmad SR, Lidington EA, Ohta R, Okada N, Robson MG, Davies KA, Leitges M,
Harris CL, Haskard DO and Mason JC (2003) Decay-accelerating factor induction
by tumour necrosis factor-alpha, through a phosphatidylinositol-3 kinase and
protein kinase C-dependent pathway, protects murine vascular endothelial cells
against complement deposition. Immunology 110 258-268
Ahmed KM, Cao N and Li JJ (2006) HER-2 and NF-kB as the targets for therapy-resistant breast cancer. Anticancer Research 26 4235-4243
Ahmed KM, Dong S, Fan M and Li JJ (2006) Nuclear Factor-kB p65 inhibits mitogen-activated protein kinase signaling pathway in radioresistant breast cancer cells. Molecular Cancer Research 4 945-955 Ahmed KM and Li JJ (2007) ATM-NF-kB connection as a target for tumor radiosensitization. Current Cancer Drug Targets 7 335-342
Ahmed KM and Li JJ (2008) NF-kB-mediated adaptive resistance to ionizing radiation. Free Radical Biology and Medicine 44 1-13
Ahmed MM (2004) Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors. Current Cancer Drug Targets 4 43-52
Ahmed S, Pakozdi A and Koch AE (2006) Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts. Arthritis and Rheumatism 54 2393-2401
Ahmed S, Wang N, Hafeez BB, Cheruvu VK and Haqqi TM (2005)
Punica granatum L. extract inhibits IL-1beta-induced expression of matrix
metalloproteinases by inhibiting the activation of MAP kinases and NF-kB in
human chondrocytes in vitro. Journal
of Nutrition 135 2096-2102
Ahn E, Lee H and Yun Y (2006) LIME acts as a transmembrane
adapter mediating BCR-dependent B cell activation. Blood 107 1521-1527
Ahn J, Feldman G, Terry L, Shore EM and Kaplan FS (2003) Exoneration of NF-kB
dysregulation in fibrodysplasia ossificans progressiva. Clinical Orthopedics
406 205-213
Ahn JY, Choi IS, Shim JY, Yun EK, Yun YS, Jeong G and Song JY (2005) The immunomodulator ginsan induces resistance to experimental sepsis by inhibiting Toll-like receptor-mediated inflammatory signals. European Journal of Immunology 36 37-45 Ahn KS and Aggarwal BB (2005) Transcription factor NF-kB: a sensor for smoke and stress signals. Annals of the New York Academy of Sciences 1056 218-233
Ahe KS, Gong x, Sethi G, Chaturvedi MM, Jaiswal AK and Aggarwal BB (2007) Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases. Cancer Research 67 10004-10011 Ahn KS, Hahn BS, Kwack K, Lee EB and Kim YS (2006) Platycodin D-induced apoptosis through nuclear factor-kB activation in immortalized keratinocytes. European Journal Pharmacology 537 1-11
Ahn KS, Moon KY, Lee J and Kim YS (2003) Downregulation of NF-kB activation in
human keratinocytes by melanogenic inhibitors. Journal of Dermatological Science 31
193-201
Ahn
KS, Noh EJ, Zhao HL, Jung SH, Kang SS and Kim YS (2005) Inhibition of
inducible nitric oxide synthase and cyclooxygenase II by Platycodon
grandiflorum saponins via suppression of nuclear factor-kB activation in RAW
264.7 cells. Life Sciences 76 2315-2328
Ahn KS, Sethi G and Aggarwal BB (2007) Simvastatin potentiates TNF-alpha-induced apoptosis through the down-regulation of NF-kB-dependent antiapoptotic gene products: role of IkBa kinase and TGF-beta-activated kinase-1. Journal of Immunology 178 2507-2516 Ahn KS, Sethi G and Aggarwal BB (2007) Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kB pathway. Biochemical Pharmacology in press Ahn KS, Sethi G and Aggarwal BB (2007) Nuclear factor-kB: from clone to clinic. Current Molecular Medicine 7 619-637
Ahn KS, Sethi G, Chaturvedi MM, Palladino MA, Younes A and Aggarwal BB (2007) Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through downmodulation of NF-kB-regulated gene products. Blood 110 2286-2295 Ahn KS, Sethi G, Jain Ak, Jaiswal AK and Aggarwal BB (2006) Genetic deletion of NAD(PPH:quinone oxidoreductase 1 abrogates activation of nuclear factor-kB, IkBa kinase c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and protentiates apoptosis. Journal of Biological Chemistry 281 19798-19808
Ahn KS, Sethi G, Krishnan K and Aggarwal BB (2007) gamma -tocotrienol inhibits nuclear factor-kB signaling pathway through inhibition of RIP and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. Journal of Biological Chemistry 282 809-820 Ahn KS, Sethi G, Shishodia S, Sung B, Arbiser JL and Aggarwal BB (2006) Honokiol potentiates apoptosis, suppresses Osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kB activation pathway. Molecular Cancer Research 4 621-633 Ahn KY, Kim BH, Lee YR, Hwang DH, Chung EY, Min K and Kim Y (2005) Dual
inhibitory effects of furonaphthoquinone compound on enzyme activity and
lipopolysaccharide-induced expression of cyclooxygenase-2 in macrophages.
Biochemical and Biophysical Research Communications 336 93-99 Ahn
SC, Kim GY, Kim JH, Baik SW, Han MK, Lee HJ, Moon DO, Lee CM, Kang JH, Kim BH,
Oh YH and Park YM (2004) Epigallocatechin-3-gallate, constituent of green tea,
suppresses the LPS-induced phenotypic and functional maturation of murine
dendritic cells through inhibition of mitogen-activated protein kinases and
NF-kB. Biochemical and Biophysical Research Communications 313 148-155 Ahn SK, Choe TB and Kwon TJ (2003) The gene expression profile of human umbilical vein endothelial cells stimulated with lipopolysaccharide using cDNA microarray analysis. International Journal of Molecular Medicine 12 231-236
Ahn SY, Cho CH, Park KG, Lee HJ, Lee S, Park SK, Lee IK and Koh GY (2004) Tumor necrosis factor-alpha induces fractalkine expression preferentially in arterial endothelial cells and mithramycin A suppresses TNF-alpha-induced fractalkine expression. American Journal of Pathology 164 1663-1672
Ahtoniemi T, Goldsteins G, Keksa-Goldsteine V, Malm T, Kanninen K, Salminen A and Koistinaho J (2007) Pyrrolidine dithiocarbamate inhibits induction of immunoproteasome and decreases survival in a rat model of amyotrophic lateral sclerosis. Molecular Pharmacology 71 30-37
Ahuja J, Lepoutre V, Wigdahl B, Khan ZK and Jain P (2007) Induction of pro-inflammatory cytokines by human T-cell leukemia virus type-1 Tax protein as determined by multiplexed cytokine protein array analyses of human dendritic cells. Biomedicine & Pharmacotherapy 61 201-208 Aiamkitsumrit B, Zhang X, Block TM, Norton P, Fraser NW and Su YH (2007) Herpes simplex virus type 1 ICP4 deletion mutant virus d120 infection failed to induce apoptosis in nerve growth factor-differentiated PC12 cells. Journal of Neurovirology 13 305-314 Aifantis
I, Gounari F, Scorrano L, Borowski C, von Boehmer H (2001) Constitutive pre-TCR
signaling promotes differentiation through Ca2+ mobilization and activation of
NF-kB and NFAT. Nature Immunology 2 403-409
Aikawa Y, Yamamoto M, Yamamoto T, Morimoto K, Tanaka K (2002) An
anti-rheumatic agent T-614 inhibits NF-kB activation in LPS- and TNF-alpha-stimulated
THP-1 cells without interfering with IkBa degradation. Inflammation Research
51 188-194 Ainbinder E, Amir-Zilberstein L, Yamaguchi Y, Handa H and Dikstein R (2004)
Elongation inhibition by DRB sensitivity-inducing factor is regulated by the
A20 promoter via a novel negative element and NF-kB. Molecular and Cellular
Biology 24 2444-2454 Ait-Ghezala G, Mathura VS, Laporte V, Quadros A, Paris D, Patel N, VOlmar CH,
Kolippakkam D, Crawford F and Mullan M (2005) Genomic regulation after CD40
stimulation in microglia: Relevance to Alzheimer's disease. Brain Research
Molecular Brain Research 140 73-85
Ait-Said F, Elalamy I, Werts C, Gomard MT, Jacquemin C, Couetil JP and Hatmi M
(2003) Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2
expression in human microvascular endothelial cells: involvement of
lipoxygenase-derived metabolites and p38 MAPK pathway. Biochimica et
Biophysica Acta 1631 77-84 279 70-76
Aizawa S, Nakano H, Ishida T, Horie R, Nagai
M, Ito K, Yagita H, Okumura K,
Inoue J and Watanabe T (1997) Tumor necrosis factor receptor-associated
factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkB activation.
Journal of Biological Chemistry 272 2042-2045
Akesson A, Ingvarsson S, Brady K, Moynagh P and Borrebaeck CA (2000) Rapid
polarization of Th2 cells during induction of antigen-specific IgE antibodies
in vitro. Clinical and Experimental Allergy 30 1298-1306
Akhtar M, Watson JL, Nazli A and McKay DM (2003) Bacterial DNA evokes
epithelial IL-8 production by a MAPK-dependent, NF-kB-independent pathway.
FASEB Journal 17 1319-1321 Akiba H, Nakano H,
Nishinaka S, Shindo M, Kobata T, Atsuta M, Morimoto C, Ware
CF, Malinin NL, Wallach D, Yagita H and Okumura K (1998) CD27, a member of the
tumor necrosis factor receptor superfamily, activates NF-kB and
stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and
NF-kB-inducing kinase. Journal of Biological Chemistry 273 13353-13358 Akin
M, Demirbilek S, Ay S, Gurunluoglu K, Turkmen E, Tas E, Aksoy RT, Baykarabulut
A and Edali MN (2007) Attenuation of ureteral obstruction-induced renal injury
by polyenylphosphatidylcholine. Akioka
K, Kirkin R, Wang M, Tian L, Yu J, Stepkowski SM and Kahan BD (1999) Reduced
expression of NF-AT and NF-kB transcription factors in tolerant recipients
treated with tolerogenic allochimeric donor/recipient class I MHC protein.
Transplantation Proceedings 31 2745-2746 Akira S, Hoshino K and Kaisho T (2000) The role of Toll-like receptors and
MyD88 in innate immune responses. Journal of Endotoxin Research 6 383-387 Akira S and Sato S (2003) Toll-like receptors and their signaling mechanisms. Scandinavian Journal of Infectious Diseases 35 555-562 Akira
S and Takeda K (2004) Functions of toll-like receptors: lessons from KO mice.
C R Biol 327 581-589 Akiyama M, Hideshima T, Hayashi T, Tai YT, Mitsiades CS, Mitsiades N, Chauhan
D, Richardson P, Munshi NC and Anderson KC (2002) Cytokines modulate
telomerase activity in a human multiple myeloma cell line. Cancer Research 62
3876-3882
Akiyama M, Yamada O, Hideshima T, Yanagisawa T, Yokoi K, Fujisawa K, Eto Y,
Yamada H and Anderson KC (2004) TNFa induces rapid activation and nuclear
translocation of telomerase in human lymphocytes. Biochemical and Biophysical
Research Communications 316 528-532 Aksoy E, Amraoui Z, Goriely S, Goldman M and Willems F (2002) Critical role of protein kinase C epsilon for lipopolysaccharide-induced IL-12 synthesis in monocyte-derived dendritic cells. European Journal of Immunology 32 3040-3049
Aksoy E, Amraoui Z, Goriely S, Goldman M and Willems F (2002) Critical role of
protein kinase C epsilon for lipopolysaccharide-induced IL-12 synthesis in
monocyte-derived dendritic cells. European Journal of Immunology 32
3040-3049
Aksoy E, Zouain C, Vanhoutte F, Fontaine J, Pavelka N, Thieblemont N, Willems
F, Ricciardi-Castagnoli P, Goldman M, Capron M, Ryffel B and Trottein F (2004)
Double-stranded RNAs from the helminth parasite Schistosoma activate TLR3 in
dendritic cells. Journal of Biological Chemistry 280 277-283 Aktan F, Henness S, Tran VH, Duke CC, Roufogalis BD and Ammit AJ (2006) Gingerol metabolite and a synthetic analogue capsarol inhibit macrophage NF-kB-mediated iNOS gene expression and enzyme activity. Planta Medica 72 727-734 Al-Lamki RS, Wang J, Tolkovsky AM, Bradley JA, Griffin JL, Thiru S, Wang EC, Bolton E, Min W, Moore P, Pober JS and Bradley JR (2008) TL1A both promotes and protects from renal inflammation and injury. Journal of The American Society of Nephrology in press
Alaaeddine N, Di Battista JA, Pelletier JP, Kiansa K, Cloutier JM and
Martel-Pelletier J (1999) Differential effects of IL-8, LIF (pro-inflammatory)
and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on
signalling pathways in human OA synovial fibroblasts. Cytokine 11 1020-1030 Alaikov T, Konstantinov SM, Tzanova T, Dinev K, Topashka-Ancheva M and Berger MR (2007) Antineoplastic and anticlastogenic properties of curcumin. Annals of the New York Academy of Sciences 1095 355-370 Alaish SM, Torres M, Ferlito M, Sun CC and De Maio A (2005) The severity of cholestatic injury is modulated by the genetic background. Shock 24 412-416 Alam J and Cook JL (2007) How many transcription factors does it take to turn on the heme oxygenase-1 gene? American Journal of Respiratory Cell and Molecular Biology 36 166-174 Alam M, Wang JH, Coffey JC, Qadri SS, O'Donnell A, Aherne T, Redmond HP (2007) Characterization of the effects of cyclooxygenase-2 inhibition in the regulation of apoptosis in human small and non-small cell lung cancer cell lines. Annals of Surgical Oncology in press Alameddine
AK (1999) Minding the chaperones. Annals of Thoracic Surgery 68 628 Alaniz L, Garcia M, Cabrera P, Arnaiz M, Cavaliere V, Blanco G, Alvarez E and
Hajos S (2004) Modulation of matrix metalloproteinase-9 activity by hyaluronan
is dependent on NF-kB activity in lymphoma cell lines with dissimilar invasive
behavior. Biochemical and Biophysical Research Communications 324 736-743 Alaoui-El-Azher M, Wu Y, Havet N, Israel A, Lilienbaum A and Touqui L (2002)
Arachidonic acid differentially affects basal and lipopolysaccharide-induced
sPLA(2)-IIA expression in alveolar macrophages through NF-kB and PPAR-g-dependent pathways. Molecular Pharmacology 61 786-794 Al-Ashy R, Chakroun I, El-Sabban ME and Homaidan FR (2006) The role of NF-kB in mediating the anti-inflammatory effects of IL-10 in intestinal epithelial cells. Cytokine 36 1-8 Albanesi C, Fairchild HR, Madonna S, Scarponi C, De Pita O, Leung DY and Howell MD (2007) IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3. Journal of Immunology 179 984-992 Albanese C, Wu K, D'Amico M, Jarrett C, Joyce D, Hughes
J, Hulit J, Sakamaki T, Fu M, Ben-Ze'ev A, Bromberg JF, Lamberti C, Verma U,
Gaynor RB, Byers SW and Pestell RG (2003) IKKalpha regulates mitogenic
signaling through transcriptional induction of cyclin D1 via Tcf. Molecular
Biology of the Cell 14 585-599 Albensi BC (2001) Potential roles for tumor necrosis
factor and nuclear factor-kB in seizure activity. Journal of Neuroscience
Research 66 151-154 Albertella
MR and Campbell RD (1994) Characterization of a novel gene in the human major
histocompatibility complex that encodes a potential new member of the IkB
family of proteins. Human Molecular Genetics 3 793-799 Albor A, El-Hizawi S, Horn EJ, Laederich M, Frosk P, Wrogemann K and Kulesz-Martin M (2006) The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in LGMD2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkB. Journal of Biological Chemistry 281 25850-25866 Albor A and Kulesz-Martin M (2007) Novel initiation genes in squamous cell carcinomagenesis: A role for substrate-specific ubiquitylation in the control of cell survival. Molecular Carcinogenesis 46 585-590 Albrecht C, Borm PJ and Unfried K (2004) Signal transduction pathways relevant
for neoplastic effects of fibrous and non-fibrous particles. Mutation Research
553 23-35 Alcamí J, de Delera
TL, Folgueira L, Pedraza M-A, Jacqué J-M, Bachelerie F, Noriega AR, Hay RT,
Harrich D, Gaynor RB, Virelizier J-L and Arenzana-Seisdedos F (1995) Absolute
dependence on kB responsive elements for initiation and Tat-mediated
amplification of HIV transcription in blood CD4 T lymphocytes. EMBO Journal 14
1552-1560 Aldonyte R, Jansson L and Janciauskiene S (2004) Concentration-dependent
effects of native and polymerised alpha1-antitrypsin on primary human
monocytes, in vitro. BMC Cell Biology 5 11 Aleffi S, Petrai I, Bertolani C, Parola M, Colombatto S, Novo E, Vizzutti F, Anania FA, Milani S, Rombouts K, Laffi G, Pinzani M and Marra F (2005) Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells. Hepatology 42 1339-1348 Aleksic T, Baumann B, Wagner M, Adler G, Wirth T and Weber CK (2007) Cellular immune reaction in the pancreas is induced by constitutively active IKK2. Gut 56 227-236 Alexander G, Carlsen H and Blomhoff R (2003) Strong in vivo activation of
NF-kB in mouse lenses by classic stressors. Invest Ophthalmol Vis Sci 44
2683-2688 Alexander L, Illyinskii PO, Lang SM, Means RE, Lifson J, Mansfield K and
Desrosiers RC (2003) Determinants of increased replicative capacity of
serially passaged simian immunodeficiency virus with nef deleted in rhesus
monkeys. Journal of Virology 77 6823-6835
Alexanian
AR and Bamburg JR (1999) Neuronal survival activity of s100betabeta is
enhanced by calcineurin inhibitors and requires activation of NF-kB. FASEB
Journal 13 1611-1620 Alexatki A, Quiterio SJ, Liu Y, Irish B, Kilareski E, Nonnemacher MR and Wigdahl B (2007) PMA-induced differentiation of a bone marrow progenitor cell line activates HIV-1 LTR-driven transcription. DNA Cell Biology 26 387-394 Alexis NE, Brickey WJ, Lay JC, Wang Y, Roubey RA, Ting JP and Peden DB (2008) Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals. Annals of Allergy Asthma and Immunology 100 206-215 Alexopoulou L, Holt AC, Medzhitov and Flavell RA (2001)
Recognition of double-stranded RNA and activation of NF-kB by Toll-like
receptor 3. Nature 413 732-738 Alfano M, Vallanti G, Biswas P, Bovolenta C, Vicenzi E, Mantelli B, Pushkarsky
T, Rappuoli R, Lazzarin A, Bukrinsky M and Poli G (2001) The binding subunit
of pertussis toxin inhibits HIV replication in human macrophages and virus
expression in chronically infected promonocytic U1 cells. Journal of
Immunology 166 1863-1870 Alford KA, Glennie S, Turrell BR, Rawlinson L, Saklatvala J and Dean JL (2007) HSP27 functions in inflammatory gene expression and TAK1-mediated signalling. Journal of Biological Chemistry 282 6232-2641 Alford PB, Xue Y, Thai SF and Shackelford RE (1998) Maleylated-BSA enhances
production of nitric oxide from macrophages. Biochemical and Biophysical
Research Communications 245 185-189 Algarté
M, Nguyen H, Heylbroeck C, Lin R and Hiscott J (1999) IkB-mediated inhibition
of virus-induced beta interferon transcription. Journal of Virology 73
2694-2702 Algul
H, Adler G and Schmid RM (2002) NF-kB/Rel transcriptional pathway:
implications in pancreatic cancer. International Journal of Gastrointestinal
Cancer 31 71-78 Algul H, Wagner M, Lesina M and Schmid RM (2007) Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation. International Journal of Cancer 121 1410-1416 Al-Harthi
L and Roebuck KA (1998) Human immunodeficiency virus type-1 transcription:
role of the 5’-untranslated leader region. International Journal of
Molecular Medicine 1 875-881 Al-Harthi
L, Roebuck KA, Olinger GG, Landay A, Sha BE, Hashemi FB and Spear GT (1999)
Bacterial vaginosis-associated microflora isolated from the female genital
tract activates HIV-1 expression. Journal of Acquired Immune Deficiency
Syndrome 21 194-202 Al-Harthi
L, Spear GT, Hashemi FB, Landay A, Sha BE and Roebuck KA (1998) A human
immunodeficiency virus (HIV)-inducing factor from the female genital tract
activates HIV-1 gene expression through the kB enhancer. Journal of Infectious
Diseases 178 1343-1351 Ali S, Banerjee S, Zhmad A, El-Rayes BF, Philip PA and Sarkar FH (2008) Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer. Molecular Cancer Therapeutics 7 1708-1719 Ali S, El-Rayes BG, Sarkar FH and Philip PA (2005) Simultaneous targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways for pancreatic cancer therapy. Molecular Cancer Therapy 4 1943-1951 Ali S, Huber M, Kollewe C, Bischoff SC, Falk W and Martin MU (2007) IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proceedings of the National Academy of Sciences USA in press Ali S and Mann DA (2004) Signal transduction via the NF-kB pathway: a targeted treatment modality for infection, inflammation and repair. Cell Biochemistry and Function 22 67-79 Alikhani M, Alikhani Z, Boyd C, Maclellan CM, Raptis M, Liu R, Pischon N, Trackman PC, Gerstenfeld L and Graves DT (2007) Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. Bone 40 345-353 Aliprantis
AO, Weiss DS and Zychlinsky A (2001) Toll-like receptor-2 transduces signals
for NF-kB activation, apoptosis and reactive oxygen species production.
Journal of Endotoxin Research 7 287-291 Aliprantis
AO, Yang RB, Mark MR, Suggett S, Devaux B, Radolf JD, Klimpel GR, Godowski P
and Zychlinsky A (1999) Cell activation and apoptosis by bacterial
lipoproteins through toll-like receptor-2. Science 285 736-739 Aliprantis AO, Yang RB, Weiss DS, Godowski P and Zychlinsky A (2000) The apoptotic signaling pathway activated by Toll-like receptor-2. EMBO Journal 19 3325-3336 Alison MR and
Lovell MJ (2005) Liver cancer: the role of stem cells. Cell Proliferation 38
407-421 Aljada A, Friedman J, Ghanim H, MOhanty P, Hofmeyer D, Chaudhuri A and Dandona P (2006) Glucose ingestion induces an increase in intranuclear nuclear factor kappaB, a fall in cellular inhibitor kB, and an increase in tumor necrosis factor alpha messenger RNA by mononuclear cells in healthy human subjects. Metabolism 55 1177-1185 Aljada
A, Garg R, Ghanim H, Mohanty P, Hamouda W, Assian E and Dandona P (2001)
Nuclear factor-kB suppressive and inhibitor-kB stimulatory effects of
troglitazone in obese patients with type 2 diabetes: evidence of an
anti-inflammatory action? J Clin Endocrinol Metab 86 3250-3256 Aljada
A, Ghanim H, Assian E, Mohanty P, Hamouda W, Garg R and Dandona P (1999)
Increased IkB expression and diminished nuclear NF-kB in human mononuclear
cells following hydrocortisone injection. Journal of Clinical Endocrinology
and Metabolism 84 3386-3389
Aljada
A, Ghanim H, Saadeh R and Dandona P (2001) Insulin inhibits NFkB and MCP-1
expression in human aortic endothelial cells. Journal of Clinical Endocrinology
and Metabolism 86
450-453 Alkalay
I, Yaron A, Hatzubai A, Orian A, Ciechanover A and Ben-Neriah Y (1995)
Stimulation-dependent IkBa phosphorylation marks the NF-kB inhibitor for
degradation via the ubiquitin-proteasome pathway. Proceedings of the National
Academy of Sciences USA 92 10599-10603 Allcock
RJ, Baluchova K, Cheong KY and Price P (2001) Haplotypic single nucleotide
polymorphisms in the central MHC gene IKBL, a potential regulator of NF-kB
function. Immunogenetics 52 289-293 Allcock
RJ, Christiansen FT and Price P (1999) The central MHC gene IKBL carries a
structural polymorphism that is associated with HLA-A3, B7, DR15. Immunogenetics 49 660-665 Alldridge
LC, Harris HJ, Plevin R, Hannon R and Bryant CE (1999) The annexin protein
lipocortin 1 regulates the MAPK/ERK pathway. Journal of Biological Chemistry
274 37620-37628 Allen C, Saigal K, Nottingham L, Arun P, Chen Z and Van Waes C (2008) Bortezomib-induced apoptosis with limited clinical response is accompanied by inhibition of canonical but not alternative nuclear factor-kB subunits in head and neck cancer. Clinical Cancer Research 14 4175-4185 Allen CE, Richards J, Muthusamy N, Auer H, Liu Y, Robinson ML, Barnard JA and Wu L-C (2008) Disruption of ZAS3 in mice alters NF-kB and AP-1 DNA binding amd T-cell development. Gene Expression 14 83-100 Allen CT, Ricker JL, Chen Z and Van Waes C (2007) Role of activated nuclear factor-kappaB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck. Head & Neck 29 959-971 Allen GL, Menendez IY, Ryan MA, Mazor RL, Wispe JR,
Fiedler MA and Wong HR (2000) Hyperoxia synergistically increases
TNF-alpha-induced interleukin-8 gene expression in A549 cells. American Journal
of Physiology:
Lung Cell and Molecular Physiology 278 L253-260 Alleva
DG, Johnson EB, Lio FM, Boehme SA, Conlon PJ and Crowe PD (2002) Regulation of
murine macrophage proinflammatory and anti-inflammatory cytokines by ligands
for peroxisome proliferator-activated receptor- gamma: counter-regulatory
activity by IFN-gamma. Journal of Leukocyte Biology 71 677-685 Allison
AC, Eugi EMCo-ordinate inhibition of the production of TNF, IL-1, and IL-6 by
small molecules. Annals of the New York Academy of Science 762 331-340 Almawi
WY and Melemedjian OK (2002) Negative regulation of nuclear factor-kB
activation and function by glucocorticoids. Journal of Molecular Endocrinology
28 69-78
Almond
JB and Cohen GM (2002) The proteasome: a novel target for cancer chemotherapy.
Leukemia 16 433-443
Alonso A, Bayon Y,
Mateos JJ and Sanchez Crespo M (1998) Signaling by leukocyte chemoattractant
and Fcgamma receptors in immune-complex tissue injury. Laboratory Investigation 78 377-392 Alpert D, Schwenger
P, Han J and Vilcek J (1999) Cell stress and MKK6b-mediated p38 MAP kinase
activation inhibit tumor necrosis factor-induced IkB phosphorylation and NF-kB
activation. Journal of Biological Chemistry 274 22176-22183 Alpert
D and Vilcek J (2000) Inhibition of IkB kinase activity by sodium salicylate
in vitro does not reflect its inhibitory mechanism in intact cells. Journal of
Biological Chemistry 275 10925 10929 Al-Rasheed NM, Willars GB and Brunskill NJ (2006) C-peptide signals via Galphai to protect against TNF-a-mediated apoptosis of opossum kidney proximal tubular cells. Journal of the American Society of Nephrology 17 986-995 Al-Sadi R, Ye D, Dokladny K and Ma TY (2008) Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. Journal of Immunology 180 5653-5661 Al-Sadi
RM and Kreydiyyeh SI (2003) Mediators of interleukin-1 beta action Na(+)-K(+)ATPase
in Caco-2 cells. European Cytokine Network 14 83-90 Alshaibi N, King MW, Duong T and Ghosh SK (2007) DP58, an inducible myeloid protein, is constitutively expressed in murine neuronal nuclei. Frontiers in Bioscience 12 2947-2956
Al-Shamkhani A (2004) The role of CD30 in the pathogenesis of haematopoietic
malignancies. Current Opinion in Pharmacology 4 355-359 Altavilla D, Marini H, Seminara P, Squadrito G, Minutoli L, Passaniti M, Bitto A, Calapai G, Calo M, Caputi AP and Squadrito F (2004) Protective effects of antioxidant raxofelast in alcohol-induced liver disease in mice. Pharmacology 74 6-14 Altavilla
D, Saitta A, Guarini S, Galeano M, Squadrito G, Cucinotta D, Santamaria LB,
Mazzeo AT, Campo GM, Ferlito M, Minutoli L, Bazzani C, Bertolini A, Caputi AP
and Squadrito F (2001) Oxidative stress causes nuclear factor-kB activation in
acute hypovolemic hemorrhagic shock. Free Radical Biology and Medicine 30 1055-1066 Altincicek B and Vilcinskas A (2006) Metamorphosis and collagen-IV-fragments stimulate innate immune response in the greater wax moth, Galleria mellonella. Developmental and Comparative Immunology 30 1108-1118 Altinoz MA and Korkmaz R (2004) NF-kB, macrophage migration inhibitory factor
and cyclooxygenase-inhibitions as likely mechanisms behind the acetaminophen-
and NSAID-prevention of the ovarian cancer. Neoplasma 51 239-247 Altomonte M, Pucillo
C, Damante G and Maio M (1993) Cross-linking of HLA class II antigens
modulates the release of tumor necrosis factor-alpha by the EBV-B
lymphoblastoid cell line JY. Journal of Immunology 151 5115-5122
Altucci
L, Rossin A, Raffelsberger W, Reitmair A, Chomienne C and Gronemeyer H (2001)
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine
action of tumor-selective death ligand TRAIL. Nature Medicine 7 680-686 Altura
BM and Gebrewold A (1998) Pyrrolidine dithiocarbamate attenuates
alcohol-induced leukocyte-endothelial cell interaction and cerebral vascular
damage in rats: possible role of activation of transcription factor NF-kB in
alcohol brain pathology. Alcohol 16 25-28 Altura BM, Gebrewold A,
Zheng T and Altura BT (2002) Sphingomyelinase and ceramide analogs induce
vasoconstriction and leukocyte-endothelial interactions in cerebral venules in
the intact rat brain: Insight into mechanisms and possible relation to brain
injury and stroke. Brain Res Bull 58 271-278 Alvarez S and Evelson PA (2007) Nitric oxide and oxygen metabolism in inflammatory conditions: sepsis and exposition to polluted ambients. Frontiers in Bioscience 12 964-974 Alvarez S, Serramia MJ, Fresno M and Munoz-Fernandez M (2005) Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism. Journal of Neurochemistry 94 850-861 Alvarez S, Serramia MJ, Fresno M and Munoz-Fernandez M (2007) HIV-1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in astrocytoma cells through a nuclear factor-kappaB-dependent mechanism. Neuromolecular Medicine 9 179-193 Alvarez-Castelao B and Castano JG (2005) Mechanism of direct degradation of IkBa by 20S proteasome. FEBS Letters 579 4797-4802 Alvarez-Maqueda M, El Bekay R, Alba G, Monteseirin J, Chacon P, Vega A, Martin-Nieto J, Bedoya FJ, Pintado E and Sobrino F (2004) 15-Deoxy-u12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. Journal of Biological Chemistry 279 21929-21937 Alvarez-Soria MA, Herrero-Beaumont G, Sanchez-Pernaute O, Bellido M and Largo R (2008) Diacerein has a weak effect on the catabolic pathway of human osteoarthritis synovial fibroblast--comparison to its effects on osteoarthritic chondrocytes. Rheumatology (Oxford) 47 627-633 Alvaro T, Lejeune M, Garcia JF, Salvado MT, Lopez C, Bosch R, Jaen J, Escriva P and Pons LE (2008) Tumor-infiltrated immune response correlates with alterations in the apoptotic and cell cycle pathways in Hodgkin and Reed-Sternberg cells. Clinical Cancer Research 14 685-691 Alves M, Calegari VC, Cunha DA, Saad MJ, Vellose LA and Rocha EM (2005) Increased expression of advanced glycation end-products and their receptor, and activation of nuclear factor kappa-B in lacrimal glands of diabetic rats. Diabetologia 48 2675-2681 Alves M,
Cunha DA, Calegari VC, Saad MJ, Boschero AC, Velloso LA and Rocha EM (2005)
Nuclear factor-kappaB and advanced glycation end-products expression in
lacrimal glands of aging rats. Journal of Endocrinology 187 159-166 Al-Zoubi AM, Efimova EV, Kaithamana S, Martinez O, El-Idrissi Mel-A, Dogan RE
and Prabhakar BS (2001) Contrasting effects of IG20 and its splice isoforms,
MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and
activation of caspase-8 and -3. Journal of Biological Chemistry 276
47202-47211 Amann R and Peskar BA (2002) Anti-inflammatory effects of aspirin and sodium
salicylate. European Journal of Pharmacology 447 1-9 Amanullah A, Azam N, Balliet A, Hollander C, Hoffman B, Fornace A and Liebermann D (2003) Cell signalling: cell survival and a Gadd45-factor deficiency. Nature 424 741 Amar S, Zhou Q, Shaik-Dasthagirisaheb Y and Leeman S (2007) Diet-induced obesity in mice causes changes in immune responses and bone loss manifested by bacterial challenge. Proceedings of the National Academy of Sciences USA 104 20466-20471 Amaro
MJ, Bartolome J and Carreno V (1999) Hepatitis B virus X protein
transactivates the inducible nitric oxide synthase promoter. Hepatology 29
915-923 Amato
SF, Swart JM, Berg M, Wanebo HJ, Mehta SR and Chiles TC (1998) Transient
stimulation of the c-Jun-NH2-terminal kinase/activator protein 1 pathway and
inhibition of extracellular signal-regulated kinase are early effects in
paclitaxel-mediated apoptosis in human B lymphoblasts. Cancer Research 58
241-247 Amberger A, Hala M,
Saurwein-Teissl M, Metzler B, Grubeck-Loebenstein B, Xu Q and Wick G (1999)
Suppressive effects of anti-inflammatory agents on human endothelial cell
activation and induction of heat shock proteins. Molecular Medicine 5 117-128
Ambili R, Santhi WS, Janam P, Nandakumar K and Pillai MR (2005) Expression of activated transcription factor nuclear factor-kB in periodontally diseased tissues. Journal of Periodontology 76 1148-1153 Ambra R, Di Nardo P, Fantini C, Minieri M, Canali R, Natella F, Virgili F (2002) Selective changes in DNA binding activity of transcription factors in UM-X7.1 cardiomyopathic hamsters. Life Sciences 71 2369-2381 Ambrosch A, Muller R, Freytag C, Borgmann S, Kraus J, Dierkes J, Neumann
KH and Konig W (2002) Small-sized low-density lipoproteins of subclass B from
patients with end-stage renal disease effectively augment tumor necrosis
factor-alpha- induced adhesive properties in human endothelial cells. American
Journal of Kidney Disease 39 972-984 Amcheslavsky A and Bar-Shavit Z (2006) Interleukin (IL)-12 mediates the anti-osteoclastogenic activity of CpG-oligodeoxynucleotides. Journal of Cellular Physiology 207 244-250 Amcheslavsky A, Zou W and Bar-Shavit Z (2004) Toll-like receptor 9 regulates TNF-alpha expression by different mechanisms:Implications for osteoclastogenesis. Journal of Biological Chemistry 279 54039-54045 Ameixa
C and Friedland JS (2001) Down-regulation of interleukin-8 secretion from
Mycobacterium tuberculosis-infected monocytes by interleukin-4 and -10 but not
by interleukin-13. Infection and Immunity 69 2470-2476 Ameixa
C and Friedland JS (2002) Interleukin-8 secretion from Mycobacterium
tuberculosis-infected monocytes is regulated by protein tyrosine kinases but
not by ERK1/2 or p38 mitogen-activated protein kinases. Infection and Immunity
70 4743-4746 Amici C, Rossi A, Costanzo A, Ciafre S, Marinari B, Balsamo M, Levrero M and Santoro MG (2006) Herpes simplex virus disrupts NF-kB regulation by blocking its recruitment on the IkB promoter and directing the factor on viral genes. Journal of Biological Chemistry 281 7110-7117 Amigo M, Paya M, Braza-Biols A, De Rosa S and Terencio MC (2008) Avarol inhibits TNF-alpha generation and NF-kB activation in human cells and in animal models. Life Sciences 82 256-264 Amigo M, Paya M, De Rosa S and Terencio MC (2007) Antipsoriatic effects of avarol-3'-thiosalicylate are mediated by inhibition of TNF-a generation and NF-kB activation in mouse skin. British Journal of Pharmacology 152 353-362 Amigo M, Schalkwijk J, Olthuis D, De Rosa S, Paya M, Terncio MC and Lamme E (2006) Identification of avarol derivatives as potential antipsoriatic drugs using an in vitro model for keratinocyte growth and differentiation. Life Sciences 79 2395-2404 Amigo M, Terencio MC, Paya M, Iodice C and Rosa SD (2007) Synthesis and evaluation of diverse thio avarol derivatives as potential UVB photoprotective candidates. Bioorganic & Medicinal Chemistry Letters 17 2561-2565 Amin MA, Haas CS, Zhu K, Mansfield PJ, Kim MJ, Lackowski NP and Koch AE (2006) Migration inhibitory factor upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 via Src, PI3 kinase, and NFkB. Blood 107 2252-2261 Amin MA, Ruth JH, Haas CS, Pakozdi A, Mansfield PJ, Haglishenas J and Koch AE (2008) H-2g, a glucose analog of blood group H antigen, mediates mononuclear cell recruitment via Src and phosphatidylinositol 3-kinase pathways. Arthritis Rheumatism 58 689-695 Amin RH and Schlissel MS (2005) NF-kB comes home. Immunity 22 401-402 Amini
S, Clavo A, Nadraga Y, Giordano A, Khalili K and Sawaya BE (2002) Interplay
between cdk9 and NF-kB factors determines the level of HIV-1 gene
transcription in astrocytic cells. Oncogene 21 5797-5803 Amir RE, Haecker H, Karin M and Ciechanover A (2003) Mechanism of processing
of the NF-kB2 p100 precursor: identification of the specific polyubiquitin
chain-anchoring lysine residue and analysis of the role of NEDD8-modification
on the SCF(beta-TrCP) ubiquitin ligase. Oncogene 23 2540-2547 Amir-Zilberstein L, Ainbinder E, Toube L, Yamaguchi Y, Handa H and Dikstein R (2007) Differential regulation of NF-kB by elongation factors is determined by core promoter type. Molecular and Cellular Biology 27 5246-5259 Amir-Zilberstein L and Dikstein R (2008) Interplay between E-box and NF-kB in regulation of A20 gene by DSIF. Journal of Biological Chemistry 283 1317-1323 Amiri KI, Ha HC, Smulson ME and Richmond A (2006) Differential regulation of CXC ligand 1 transcription in melanoma cell lines by poly(ADP-ribose) polymerase-1. Oncogene 25 7714-7722 Amiri KI, Horton LW, LaFleur BJ, Sosman JA and Richmond A (2004) Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for Bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma. Cancer Research 64 4912-4918
Amiri
KI and Richmond A (2005) Role of nuclear factor-kB in melanoma. Cancer
Metastasis Review 24 301-313
Amit S and Ben-Neriah Y (2003) NF-kB activation in cancer: a challenge for
ubiquitination- and proteasome-based therapeutic approach. Seminars in Cancer
Biology 13 15-28
Ammirante M, Rosati A, Gentilella A, Festa M, Petrella A, Marzullo L, Poscale M, Belisaria MA, Leone A and Turco MC (2008) The activity of the hsp90alpha promoter is regulated by NF-kB transcription factors. Oncogene 27 1175-1178
Ammon HP (2006) Bowellic acids in cheonic inflammatory diseases. Planta Medica 72 1100-1116
Ammon C, Mondal K, Andreesen R and Krause SW (2000)
Differential expression of the transcription factor NF-B during human
mononuclear phagocyte differentiation to macrophages and dendritic cells.
Biochemical and Biophysical Research Communications 268 99-105
Amoli MM, Mousavizadeh R, Sorouri R, Rahmani M and Larijani B (2006) Curcumin inhibits in vitro MCP-1 release from muse pancreatic islets. Transplantation Proceedings 38 3035-3-38
Amore A, Conti G, Cirina P, Peruzzi L, Mollo A, Chiesa M, Turcato S,
Ghisellini L and Coppo R (2004) Biocompatibility of the acetate in the
dialysis fluid [Article in Italian]. G
Ital Nefrol 21 S91-S96
Amorino GP
and Parsons SJ (2004) Neuroendocrine cells in prostate cancer. Crit Rev
Eukaryot Gene Expr 14 287-300
Amory-Rivier
CF, Mohler J, Bedos JP, Azoulay-Dupuis E, Henin D, Muffat-Joly M, Carbon C and
Moine P (2000) Nuclear factor-kB activation in mouse lung lavage cells in
response to Streptococcus pneumoniae pulmonary infection. Critical Care Medicine 28
3249-3256 Amos N, Lauder S, Evans A, Feldmann M and Bondeson J (2006) Adenoviral gene transfer into osteoarthritis synovial cells using the endogenous inhibitor IkBa reveals that most, but not all, inflammatory and destructive mediators are NFkB dependent. Rheumatology 45 1201-1209 Amran D, Sanchez Y, Fernandez C, Ramos AM, de Blas E, Breard J, Calle C and Aller P (2007) Arsenic trioxide sensitizes promonocytic leukemia cells to TNFa-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways. Biochimica et Biophysica Acta 1773 1653-1663 Amrani
Y, Ammit AJ, Panettieri Jr RA (2001) Tumor necrosis factor receptor (TNFR) 1,
but not TNFR2, mediates tumor necrosis factor-alpha-induced interleukin-6 and
RANTES in human airway smooth muscle cells: role of p38 and p42/44
mitogen-activated protein kinases. Molecular Pharmacology 60 646-655 Amster-Choder
O and Wright A (1992) Modulation of the dimerization of a transcriptional
antiterminator protein by phosphorylation. Science 257 1395-1398 Amundson SA, Bittner M and Fornace AJ (2003) Functional genomics as a window on radiation stress signaling. Oncogene 22 5828-5833 An H, Hou J, Zhou J, Zhao W, Xu H, Zheng Y, Yu Y, Liu S and Cao X (2008) Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. Nature Immunology 9 542-550
An
H, Xu H, Yu Y, Zhang M, Qi R, Yan X, Liu S, Wang W, Guo Z, Qin Z and Cao X
(2002) Up-regulation of TLR9 gene expression by LPS in mouse macrophages via
activation of NF-kB, ERK and p38 MAPK signal pathways. Immunology Letters
81 165-169 An H, Xu H, Zhang M, Zhou J, Feng T, Qian C, Qi R and Cao X (2005) Src homology 2 domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through phosphatase activity- and PI-3K-independent mechanism. Blood 105 4685-4692 An
H, Yu Y, Zhang M, Xu H, Qi R, Yan X, Liu S, Wang W, Guo Z, Guo J, Qin Z and
Cao X (2002) Involvement of ERK, p38 and NF-kB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells. Immunology 106 38-45 An HJ, Kwon KB, Cho HI, Seo EA, Ryu DG, Hwang WJ, Yoo SJ, Kim YK, Hong SH and Kim HM (2005) Solanum nigrum produces nitric oxide via nuclear factor-kB activation in mouse peritoneal macrophages. European Cancer Prevention 14 345-350 An HJ, Um JY, Na HJ, Jeong S,Kim HM and Hong SH (2007) Activation of inducible nitric oxide synthase by Kagamjuaguiem in peritoneal macrophages in mice. Indian Journal of Medical Research 125 40-746 An J, Fisher M and Rettig MB (2004) VHL expression in renal cell carcinoma sensitizes to bortezomib (PS-341) through an NF-kB-dependent mechanism. Oncogene 18 1699-1704 An
J and Rettig MB (2005) Mechanism of von Hippel-Lindau protein-mediated
suppression of nuclear factor kB activity. Molecular and Cellular Biology 25
7546-7556 An J, Sun Y, Fisher M and Rettig MB (2004) Maximal apoptosis of renal cell carcinoma by the proteasome inhibitor bortezomib is nuclear factor-kB dependent. Molecular Cancer Therapy 3 727-736 An J, Sun Y, Fisher M and Rettig MB (2004) Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas. Leukemia 18 1699-1704 An J, Sun Y, Fisher M and Rettig MB (2004) Maximal apoptosis of renal cell carcinoma by the proteasome inhibitor bortezomib is nuclear factor-kB dependent. Molecular Cancer Therapy 3 727-736
An J, Sun YP, Adams J, Fisher M, Belldegrun A and Rettig MB (2003) Drug
interactions between the proteasome inhibitor bortezomib and cytotoxic
chemotherapy, tumor necrosis factor (TNF) alpha, and TNF-related
apoptosis-inducing ligand in prostate cancer. Clinical Cancer Research 9
4537-4545
An MM, Fan KX, Cao YB, Shen H, Zhang JD, Lu L, Gao PH and Jiang YY (2006)
Lymphtoxin beta receptor-Ig protects from T-cell-mediated liver injury in mice
through blocking LIGHT/HVEM signaling.
An
Q, Xue TY, Xu W, Gao JZ, Wu Y and Xu CP (2007) Effect of N-tosyl-L-phenylalnylchloromethyl
ketone and dexamethasone on expression of nuclear transcription factor-kB in
childhood acute lymphoblastic leukemia and its significance [Article in
Chinese]. An SJ, Pae HO, Oh GS, Choi BM, Jeong S, Jang SI, Oh H, Kwon TO, Song CE and
Chung HT (2002) Inhibition of TNF-a, IL-1b, and IL-6 productions and NF-kB
activation in lipopolysaccharide-activated RAW 264.7 macrophages by
catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don
(Bignoniaceae). International Immunopharmacology 2 1173-1181 Anagnostopoulos K, Tentes I and Kortsanis AH (2008) Cell signaling in cancer. J BUON 13 17-22 Anan A, Baskin-Bey E, Isomoto H, Mott J, Bronk SF, Albrecht JH and Gores GJ (2006) Proteasome inhibition attenuates hepatic injury in the bile duct ligated mouse. American Journal of Physiology: Gastrointestinal Liver Physiology 291 G709-G716 Anand P, Sundaram C, Jhurani S, Kunnumakkara AB and Aggarwal BB (2008) Curcumin and cancer: an "old-age" disease with an "age-old" solution. Cancer Letters in press Anandarajah AP and Ritchlin CT (2004) Pathogenesis of psoriatic arthritis. Current Opinions in Rheumatology 16 338-343 Anastasilakis AD, Goulis DG, Polyzos SA, Gerou S, Pavlidou V, Koukoulis G and Avramidis A (2008) Acute changes in serum osteoprotegerin and receptor activator for nuclear factor-kB ligand levels in women with established osteoporosis treated with teriparatide. European Journal of Endocrinology 158 411-415 Andalibi
A, Liao F, Imes S, Fogelman AM and Lusis AJ (1993) Oxidized lipoproteins
influence gene expression by causing oxidative stress and activating the
transcription factor NF-kB. Biochemical Society Transactions 21 651-655 Ananko EA, Kondrakhim YV, Merkulova TI and Kolchanov NA (2007) Recognition of interferon-inducible sites, promoters, and enhancers. BMC Bioinformatics 8 56 Andela VB (2004) Functional antagonism between NF-kB and nuclear receptors:
implications in carcinogenesis and strategies for optimal cancer
chemopreventive interventions. Current Cancer Drug Targets 4 337-344 Andela
VB, Schwarz EM, Puzas JE, O'Keefe RJ and Rosier RN (2000) Tumor metastasis and
the reciprocal regulation of prometastatic and antimetastatic factors by
nuclear factor kB. Cancer Research 60 6557-6562 Andersen L, Jensen H, Pedersen MT, Hansen KA and Skov S (2007) Molecular regulation of MHC class I chain-related protein A expression after HDAC-inhibitor treatment of Jurkat T cells. Journal of Immunology 179 8235-8242 Andersen PL, Zhou H, Pastushok L, Moraes T, McKenna S, Ziola B, Ellison MJ, Dixit VM and Xiao W (2005) Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A. Journal of Cell Biology 170 745-755 Anderson AE, Worku ML, Khamri W, Bamford KB, Walker MM and Thursz MR (2007) TLR9 polymorphisms determine murine lymphocyte responses to Helicobacter: results from a genome-wide scan. European Journal of Immunology 37 1548-1561 Anderson HD,
Rahmutula D and Gardner DG (2004) Tumor necrosis factor-alpha
inhibits endothelial nitric oxide synthase gene promoter activity in bovine
aortic endothelial cells. Journal of Biological Chemistry 179 963-969 Anderson KC (2003) Moving disease biology from the lab to the clinic. Cancer 97 796-801 Anderson KN and Bejcek BE (2008) Parthenolide induces apoptosis in glioblastomas without affecting NF-kB. Journal of Pharmacological Sciences 106 318-320 Anderson LA and Perkins ND (2003) Regulation of RelA (p65) Function by the
large subunit of replication factor C. Molecular and Cellular Biology 23
721-732 Anderson SL, Qiu J and Rubin BY (2003) Tocotrienols induce IKBKAP expression:
a possible therapy for familial dysautonomia. Biochemical and Biophysical
Research Communications 306 303-309 Anderson
MT, Wims LA and Morrison SL (1991) The plasmacytoma J558L lacks constitutively
active NF-kB and is deficient in early response gene activation. Nucleic Acids
Research 19 7235-7241 Andjelic S, Hsia C, Suzuki H, Kadowaki T, Koyasu S, Liou HC (2000) Phosphatidylinositol 3-kinase and NF-kB/Rel are at the divergence of CD40-mediated proliferation and survival pathways. Journal of Immunology 165 3860-3867 Ando A, Yamazaki Y, Kaneko S, Miyake M, Nambu R, Taomoto M, Unezaki S, Okuda-Ashitaka E, Okumura T, Ito S and Matsumura M (2005) Cytoprotection by nipradilol, an anti-glaucomatous agent, via down-regulation of apoptosis related gene expression and activation of NF-kB. Experimental Eye Research 80 501-507 Ando I, Tsukumo Y, Wakabayashi T, Akashi S, Miyake K, Kataoka T and Nagai K
(2002) Safflower polysaccharides activate the transcription factor NF-kB via
Toll-like receptor 4 and induce cytokine production by macrophages.
International Immunopharmacology 2 1155-1162 Ando K, Hirao S, Kabe Y, Ogura Y, Sato I, Yamaguchi Y, Wada T and Handa H (2008) A new APE1/Ref-1-dependent pathway leading to reduction of NF-kB and AP-1, and activation of their DNA-binding activity. Nucleic Acids Research in press Ando S, Matsuda H, Morikawa T and Yoshikawa M (2005) 1'S-1'-Acetoxychavicol acetate as a new type inhibitor of interferon-beta production in lipopolysaccharide-activated mouse peritoneal macrophages. Bioorganic Medicinal Chemistry 13 3289-3294 Ando W, Hashimoto J, Nampei A, Tsuboi H, Tateishi K, Ono T, Nakamura N, Ochi T and Yoshikawa H (2006) Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis (CIA). Journal of Bone and Mineral Metabolism 24 274-282 Andoh A, Fujino S, Bamba S, Araki Y, Okuno T, Bamba T and Fujiyama Y (2002) IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts. Journal of Immunology 169 1683-1687 Andoh
A, Fujiyama Y, Hata K, Araki Y, Takaya H, Shimada M and Bamba T (1999)
Counter-regulatory effect of sodium butyrate on tumour necrosis factor-alpha
(TNF-alpha)-induced complement C3 and factor B biosynthesis in human
intestinal epithelial cells. Clinical and Experimental Immunology
118 23-29 Andoh A, Shimada M, Takaya H, Hata K, Fujiyama Y and
Bamba T (2000) Transforming growth factor-beta1 acts as a potent inhibitor of
complement C3 biosynthesis in human pancreatic cancer cell lines. Pancreas 20
138-145 Andoh
A, Takaya H, Makino J, Sato H, Bamba S, Araki Y, Hata K, Shimada M, Okuno T,
Fujiyama Y and Bamba T (2001) Cooperation of interleukin-17 and
interferon-gamma on chemokine secretion in human fetal intestinal epithelial
cells. Clinical and Experimental Immunology 125 56-63 Andoh A, Tsujikawa T and Fujiyama Y (2003) Role of dietary fiber and short-chain Fatty acids in the colon. Current Pharmaceutical Design 9 347-358
Andoh A, Yasui H, Inatomi O, Zhang Z, Deguchi Y, Hata K, Araki
Y, Tsujikawa T, Kitoh K, Kim-Mitsuyama S, Takayanagi A, Shimizu N and Fujiyama
Y (2005) Interleukin-17 augments tumor necrosis factor-a-induced granulocyte
and granulocyte/macrophage colony-stimulating factor release from human
colonic myofibroblasts. Journal of Gastroenterology 40 802-810
Andorfer B, Kieseier BC, Mathey E, Armati P, Pollard J, Oka N and Hartung HP
(2001) Expression and distribution of transcription factor NF-kB and inhibitor
IkB in the inflamed peripheral nervous system. Journal of Neuroimmunology 116
226-232
Andrassy M, Bierhaus A, Hong M, Sis J, Schiekofer S, Humper PM, Chen J, Haap
M, Renn W, Schleicher E, Haring HU, Andrassy K and Nawroth PP (2002)
Erythropoietin-mediated decrease of the redox-sensitive transcription factor
NF-kB is inversely correlated with the hemoglobin level. Clinical Nephrology 58
179-189 Andrassy M, Volz HC, Igwe JC, Funke B, Eichberger SN, Kaya Z, Buss S, Autschbach F, Pleger ST, Lukic IK Bea F, Hardt SE, Humpert PM, Bianchi ME, Mairbaul H, Nawroth PP, Remppis A, Katus HA and Bierhaus A (2008) High-mobility group box-1 in ischemia-reperfusion injury of the heart. Circulation 117 3216-3226 Andreadi CK, Howells LM, Atherfoold PA and Manson MM (2006) Involvement of Nrf2, p38, B-raf and NF-kB, but not PI3K, in induction of hemeoxygenase (HO-1) by dietary polyphenols. Molecular Pharmacology 69 1033-1040
Andreakos E, Foxwell B, Brennan F, Maini R and Feldmann M (2002) Cytokines and
anti-cytokine biologicals in autoimmunity: present and future. Cytokine and Growth
Factor Reviews 13 299-313
Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco
C, Feldmann M and Foxwell BM (2003) Distinct pathways of LPS-induced NF-kB
activation and cytokine production in human myeloid and non-myeloid cells
defined by selective utilization of MyD88 and Mal/TIRAP. Blood 103 2229-2237 Andreakos E, Williams RO, Wales J, Foxwell BM and Feldmann M (2006) Activation of NF-kB by the intracellular expression of NF-kB-inducing kinase acts as a powerful vaccine adjuvant. Proceedings of the National Academy of Sciences USAeedings of the National Academy of Sciences USA 103 14459-14464
Andreoni
KA, Wang X, Huang SM and Huang ES (2002)
Human cytomegalovirus hyperimmune globulin not only neutralizes HCMV
infectivity, but also inhibits HCMV-induced intracellular NF-kB, Sp1, and
PI3-K signaling pathways. Journal
of Medical Virology 67 33-40
Andreoni
KA, Wang X, Huong SM and Huang ES (2001) Human CMV-IGIV (CytoGam) neutralizes
human cytomegalovirus (HCMV) infectivity and prevents intracellular signal
transduction after HCMV exposure. Transplantation and Infectious Disease 3 25-30
Andres
D, Diez-Fernandez C, Zaragoza A, Alvarez A and Cascales M (2001) Induction of
cell proliferation by cyclosporin A in primary cultures of rat hepatocytes.
Biochemical Pharmacology 61 427-435 Andresen L, Jorgensen VL, Perner A, Hansen A, Eugen-Olsen J and Rask-Madsen J (2005) Activation of nuclear factor kB in colonic mucosa from patients with collagenous and ulcerative colitis. Gut 54 503-509 Andresen
L, Eugen-Olsen J, Perner A and Rask-Madsen J (1999) NF-kB in IBD: does binding
to DNA imply transcriptional activity? Gastroenterology 116
1504-1505 Andrews
BJ and Herskowitz I (1989) The yeast SW14 protein contains a motif present in
developmental regulators and is part of a complex involved in cell-cycle-dependent transcription. Nature 342 830-833 Andriamanalijaona
R, Renard E, Legendre F, Raoudi M, Eypriotou M, Boumediene K, Gatto H,
Monginoux P and Pujol JP (2005) Comparative effects of 2 antioxidants,
selenomethionine and epigallocatechin-gallate, on catabolic and anabolic gene
expression of articular chondrocytes. Journal of Rhematology 32 1958-1967
Aneja R, Odoms K, Dunsmore K, Shanley TP and Wong HR (2006) Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells. Journal of Immunology 177 7184-7192 Anest V, Cogswell PC and Baldwin AS (2004) IKKalpha and p65/RelA
contribute to
optimal EGF-induced c-fos gene expression independent of Ikappa Balpha
degradation. Journal of Biological Chemistry 279 31183-31189 Angelo LS and Kurzrock R (2007) Vascular endothelial growth factor and its relationship to inflammatory mediators. Clinical Cancer Research 13 2825-2830 Angelopoulos NG, Goula A, Katounda E, Rombopoulos G, Kaltzidou V, Kaltsas D, Konstandelou E and Tolis G (2007) Markers of bone metabolism in eugonadal female patients with beta-thalassemia major. Pediatric Hematology and Oncology 24 481-491 Angelov D, Charra M, Muller CW, Cadet J and Dimitrov S (2003) Solution study
of the NF-kB p50-DNA complex by UV laser protein-DNA cross-linking. Photochem
Photobiol 77 592-596 Angelov
D, Lenouvel F, Hans F, Muller CW, Bouvet P, Bednar J, Moudrianakis EN, Cadet J
and Dimitrov S (2004) The histone octamer is "invisible" when NF-kB
binds to the nucleosome. Journal of Biological Chemistry 279 42374-42382 Anglani
F, Forino M, Del Prete D, Ceol M and Favaro S (2001) Molecular biology of the
peritoneal membrane: in between morphology and function. Contrib Nephrol 131
61-73 Anisowicz
A, Messineo M, Lee SW and Sager R (1991) An NF-kB-like transcription factor
mediates IL-1/TNF-a induction of gro in human fibroblasts. Journal of Immunology 147 520-527 Ankli
A, Heinrich M, Bork P, Wolfram L, Bauerfeind P, Brun R, Schmid C, Weiss C,
Bruggisser R,
Gertsch J, Wasescha M and Sticher O (2001) Yucatec Mayan
medicinal plants: evaluation based on indigenous uses. Journal of
Ethnopharmacology 79 43-52 Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Shan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, Santra M, Williams DR, Dang L, Barlogie B, Shaughnessy Jr JD, Juehl WM and Staudt LM (2007) Frequent engagement of the classical and alternative NF-kB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 12 115-130 Anonymous (1990)
Simian immune deficiency virus (SIV) strain SIV SMM-PBj 14-4.41 carrying two
copies of binding site for transcription factor NF-kB induces fulminant
disease in pig tailed macaques. Indian Journal of Experimental Biology 28
1198-1200 Anonymous (no authors listed) (2004) Link between epidermal growth factor receptor and NF-kB in human diffuse gliomas. Laboratory Investigation 84 939-940 Anrather
J, Csizmadia V, Soares MP and Winkler H (1999) Regulation of NF-kB RelA phosphorylation and transcriptional activity by p21ras and protein kinase C in primary endothelial cells.
Journal of Biological Chemistry 274 13594-13603 Anrather J, Racchumi G and Iadecola C (2006) NF-kB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. Journal of Biological Chemistry 281 5657-5667 Ansari RA and Gancy J (2007) Determining the transrepression activity of xenoestrogen on nuclear factor-kB in Cos-1 cells by estrogen receptor-alpha. International Journal of Toxicology 26 441-449 Ansari KM Rundhaug JE and Fischer SM (2008) Multiple signaling pathways are responsible for prostaglandin e2-induced murine keratinocyte proliferation. Molecular Cancer Research 6 1003-1016
Anstead
GM, Chandrasekar B, Zhang Q and Melby PC (2003) Multinutrient undernutrition
dysregulates the resident macrophage proinflammatory cytokine network, nuclear
factor-kB activation, and nitric oxide production. Journal of Leukoctye
Biology 74 982-991 Anthonsen
MW, Solhaug A and Johansen B (2001) Functional coupling between secretory and
cytosolic phospholipase A2 modulates tumor necrosis factor-alpha- and
interleukin-1beta-induced NF- kB activation. Journal of Biological Chemistry
276 30527-30536 Anto
RJ, Mukhopadhyay A, Shishodia S, Gairola CG and Aggarwal BB (2002) Cigarette
smoke condensate activates nuclear transcription factor-kB through
phosphorylation and degradation of IkBa: correlation with induction of
cyclooxygenase-2. Carcinogenesis 23 1511-1518 Antonelli A, Bianchi M, Crinelli R, Gentilini L and
Magnani M (2001) Modulation of ICAM-1 expression in ECV304 cells by
macrophage-released cytokines. Blood Cells Mol Dis 27 978-991 Antonelli
A, Crinelli R, Bianchi M, Cerasi A, Gentilini L, Serafini G and Magnani M
(1999) Efficient inhibition of macrophage TNF-alpha production upon targeted
delivery of K48R ubiquitin. British Journal of Haematology 104 475-481 Antoni
BA, Rabson AB, Kinter A, Bodkin M and Poli G (1994) NF-kB-dependent and
-independent pathways of HIV activation in a chronically infected T cell line.
Virology
202 684-694 Antonio
V, Brouillet A, Janvier B, Monne C, Bereziat G, Andreani M and Raymondjean M
(2002) Transcriptional regulation of the rat type IIA phospholipase A2 gene by
cAMP and IL-1b in vascular smooth muscle cells : interplay of C/EBP, NF-kB,
and Ets transcription factors. Biochemical Journal
368 415-424
Anwar KN, Fazal F, Malik AB and Rahman A (2004) RhoA/Rho-associated kinase
pathway selectively regulates thrombin-induced intercellular adhesion
molecule-1 expression in endothelial cells via activation of IkB kinase beta
and phosphorylation of RelA/p65. Journal of Immunology 173 6965-6972
Antony
PA and Restifo NP (2002) Do CD4+ CD25+ Immunoregulatory T
cells hinder tumor immunotherapy?
Oncogene 12 1159-1164 Anuar F, Whiteman M, Siau JL, Kwong SE, Bhatia M and Moore PK (2006) Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat. British Journal of Pharmacology 147 966-974 Ao J, Feng H and Xia F (2007) Transforming growth factor and nuclear factor kappaB mediated prophylactic cardioprotection by total flavonoids of Fructus chorspondiatis in myocardial icschemia. Cardiovascular Drugs and Therapy 21 235-241 Aoki K, Nakajima M, Hoshi Y, Saso N, Kato S, Sugiyama Y and Sato H (2008) Effect of aminoguanidine on lipopolysaccharide-induced changes in rat liver transporters and transcription factors. Biol Pharm Bull 31 412-420 Aoki K, Saito H, Itzstein C, Ishiguro M, Shibata T, Blanque R, Mian AH, Takahashi M, Suzuki Y, Yoshimatsue M, Yamaguchi A, Deprez P, Mollat P, Murali R, Ohya K, Norne WC and Baron R (2006) A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss. Journal of Clinical Investigation 116 1525-1534 Aoki K, Yamakuni T, Yoshida M and Ohizumi Y (20050 Ephedorae herba decreases lipopolysaccharide-induced cyclooxgenase-2 protein expression and NF-kB-dependent transcription in C6 rat glioma cells. Journal of Pharmacological Sciences 98 327-330 Aoki M, Nata T,
Morishita R, Matsushita H, Nakagami H, Yamamoto K, Yamazaki K, Nakabayashi M,
Ogihara T and Kaneda Y (2001) Endothelial apoptosis induced by oxidative
stress through activation of NF-kB: anti-apoptotic effect of antioxidant
agents on endothelial
cells. Hypertension 38 48-55 Aoki T, Kataoka H, Shimamura M, Nakagami H, Wakayama K, Moriwaki T, Ishibashi R, Nozaki K, Morishita R and Hashimoto N (2007) NF-kB is a key mediator of cerebral aneurysm formation. Circulation 116 2830-2840 Aoki Y
and Kao PN (1999) Erythromycin inhibits transcriptional activation of NF-?B,
but not NFAT, through calcineurin-independent signaling in T cells. Antimicrobial
Agents and Chemotherapy 43 2678-2684 Aoki
Y, Qiu D, Zhao GH and Kao PN (1998) Leukotriene B4 mediates
histamine induction of NF-kB and IL-8 in human bronchial epithelial cells.
American Journal of Physiology 274 L1030-L1039 Aono
H, Fujisawa K, Hasunuma T, Marriott SJ and Nishioka K (1998) Extracellular
human T cell leukemia virus type I tax protein stimulates the proliferation of
human synovial cells. Arthritis and Rheumatism 41 1995-2003 Aosasa
S, Ono S, Mochizuki H, Tsujimoto H, Ueno C and Matsumoto A (2001) Mechanism of
the inhibitory effect of protease inhibitor on tumor necrosis factor alpha
production of monocytes. Shock 15 101-105 Aosasa
S, Ono S, Mochizuki H, Tsujimoto H, Ueno C and Matsumoto A (2001) Mechanism of
the inhibitory effect of protease inhibitor on tumor necrosis factor alpha
production of monocytes. Shock 15 101-105 Aoudjit
F, Brochu N, Belanger B, Stratowa C, Hiscott J and Audette M (1997) Regulation
of intercellular adhesion molecule-1 gene by tumor necrosis factor-alpha is
mediated by the nuclear factor-kB heterodimers p65/p65 and p65/c-Rel in the
absence of p50. Cell Growth & Differentiation 8 335-342 Appel S, Boehmler AM, Grunebach F, Muller MR, Rupf A, Weck MM, Hartmann U,
Reichardt VL, Kanz L, Brummendorf TH and Brossart P (2004) Imatinib mesylate
affects the development and function of dendritic cells generated from
CD34+
peripheral blood progenitor cells. Blood 103 538-544 Appendino G, Maxia L, Bascope M, Houghton PJ, Sanchez-Duffhues G, Munoz E and Sterner O (2006) Merolerpenoid NF-kB inhibitor and driamine sesquiterpenoids from Asafetida. Journal of Natureal Products 69 1101-1104 Appendino G, Ottino M, Marquez N, Bianchi F, Giana A, Ballero M, Sterner O, Fiebich BL and Munoz E (2007) Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-pyrone from Helichrysum italicum ssp. microphyllum. Journal of Natural Products 70 608-612 Appledorn DM, McBride A, Seregin S, Scott JM, Schuldt N, Kiang A, Godbehere S and Amalfitano A (2008) Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors. Gene Therapy in press Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, Paramerswaran N and Amalfitano A (2008) Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. Journal of Immunology 181 2134-2144 Aprigliano I, Dudas J, Ramadon G and Saile B (2008) Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. Liver International 28 546-557 Apte M, McCarroll J, Pirola R and Wilson J (2007) Pancreatic MAP kinase pathways and acetaldehyde. Novartis Foundation Symposium 285 200-211 Apte UM, McRee R and Ramaiah SK (2004) Hepatocyte proliferation is the
possible mechanism for the transient decrease in liver injury during steatosis
stage of alcoholic liver disease. Toxicol Pathol 32 567-576 Aradhya S, Bardaro T, Galgoczy P, Yamagata T, Esposito T, Patlan H,
Ciccodicola A, Munnich A, Kenwrick S, Platzer M, D'Urso M and Nelson DL (2001)
Multiple pathogenic and benign genomic rearrangements occur at a 35 kb
duplication involving the NEMO and LAGE2 genes. Human Molecular Genetics 10 2557-2567 Arafat HA, Katakam AK, Chipitsyna G, Gong Q, Vancha AR, Gabbeta J and DaFoe DC (2007) Osteopontin protects the islets and beta cells from interleukin-1 beta-mediated cytotoxicity through negative feedback regulation of nitric oxide. Endocrinology 148 575-584 Aragno M, Mastrocola R, Brignardello E, Catalano M, Robino G, Manti R, Parola M, Danni O and Boccuzzi G (2002) Dehydroepiandrosterone modulates nuclear factor-kB activation in hippocampus of diabetic rats. Endocrinology 143 3250-3258 Aragno M, Mastrocola R, Medana C, Catalano MG, Vercellinatto I, Danni O and Boccuzzi G (2006) Oxidative stress-dependent impairment of cardiac specific transcription factors in experimental diabetes. Endocrinology 147 5697-5674 Arai
KY, Roby KF and Terranova PF (2005) Tumor necrosis factor alpha (TNF)
suppresses cAMP response element (CRE) activity and nuclear CRE binding
protein in MA-10 mouse Leydig tumor cells. Endocrine 27 17-24 Arakawa T, Nakamura
M, Yoshimoto T and Yamamoto S (1995) The transcriptional regulation of human
arachidonate 12-lipoxygenase gene by NF kB/Rel. FEBS Letters 363 105-110 Araki K, Kawauchi K and Tanaka N (2008) IKK/NF-kB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors. Oncogene in press Araki S, Dobashi K, Asayama K, and Shirahata A (2007) Simvastatin enhances induction of inducible nitric oxide synthase in 3T3-L1 adipocytes. Free Radical Research 41 1028-1034 Araki S, Dobashi K, Kubo K, Yamamoto Y, Asayman K and Shirahata A (2006) N-acetylcysteine attenuates TNF-alpha induced changes in secretion of interleukin-6, plasminogen activator inhibitor-1 and adiponectin from 3T3-L1 adipocytes. Life Sciences 79 2405-2412 Araki S, Dobashi K, Kubo K, Kawagoe R, Yamamoto Y and Shirahata A (2007) N-acetylcysteine inhibits induction of nitric oxide synthase in 3T3-L1 adipocytes. J UOEH 29 417-429 Araki S, Omori Y Lyn D, Singh RK, Meinbach DM, Sandman Y, Lokeshwar VB and Lokeshwar BL (2007) Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer. Cancer Research 67 6854-6862 Aramaki
O, Inoue F, Takayama T, Shimazu M, Kitajima M, Ikeda Y, Okumura K, Yagita H,
Shirasugi N and Niimi M (2005) Various costimulatory pathways are essential
for induction of regulatory cells by intratracheal delivery of alloantigen. Transplantation
Proceedings 37 1934-1936 Aranha MM, Borralho PM, Ravasco P, Moreira da Silva IKB, Correia L, Fernandes A, Camilo ME and Rodrigues CM (2007) NF-kB and apoptosis in colorectal tumourigenesis. European Journal of Clinical Investigation 37 416-424 Arany I, Whitehead WE, Grattendick KJ, Ember IA and Tyring SK (2002)
Suppression of growth by all-trans retinoic acid requires prolonged induction
of interferon regulatory factor 1 in cervical squamous carcinoma (SiHa) cells.
Clin Diagn Lab Immunol 9 1102-1106 Aravindan N, Natarajan M and Shaw AD (2006) Fenoldopam inhibits nuclear translocation of nuclear factor kB in a rat model of surgical ischemic acute renal failure. Journal of Cardiothoracic and Vascular Anesthesiology 20 179-186 Aravindan N, Cata JP, Dougherty PM and Shaw AD (2006) Effect of fenoldopam on ischemia/reperfusion-induced apoptosis. Renal Failure 28 337-344 Arayatrakoollikit U, Pavasant P and Yonchaitrakul T (2008) Thrombin induces osteoprotegerin synthesis via phosphatidylinositol 3'-kinase/mammalian target of rapamycin pathway in human periodontal ligament cells. Journal of Periodontal Research in press Arbault
S, Edeas M, Legrand-Poels S, Sojic N, Amatore C, Piette J, Best-Belpomme M,
Lindenbaum A and Vuillaume M (1997) Phenylarsine oxide inhibits ex vivo HIV-1
expression. Biomedical Pharmacotherapy 51 430-438 Arbibe L, Mira JP, Teusch N, Kline L, Guha M, Mackman N, Godowski PJ, Ulevitch
RJ and Knaus UGToll-like receptor 2-mediated NF-kB activation requires a
Rac1-dependent pathway. Nature Immunology 1 533-540 Arch
RH and Thompson CB (1998) 4-1BB and Ox40 are members of a tumor necrosis
factor (TNF)-nerve growth factor receptor subfamily that bind TNF
receptor-associated factors and activate nuclear factor kB. Molecular and
Cellular Biology 18 558-565 Arch
RH, Gedrich RW and Thompson CB (1998) Tumor necrosis factor
receptor-associated factors (TRAFs) - a family of adaptor proteins that
regulates life and death. Genes & Development 12 2821-2830 Arcinas
M, Heckman CA, Mehew JW and Boxer LM (2001) Molecular mechanisms of
transcriptional control of bcl-2 and c-myc in follicular and transformed
lymphoma. Cancer Research 61 5202-5206
Arden KC (2004) FoxO: linking new signaling pathways. Molecular Cell 14
416-418 Are AF,
Galkin VE, Pospelova TV and Pinaev GP (2000)
The p65/RelA subunit of NF-kB interacts with actin-containing structures.
Experimental Cell Research 256 533-544 Arechiga AF, Bell BD, Solomon JC, Chu IH, Dubois CL, Hall BE, George TC, Coder DM and Walsh CM (2005) FADD is not required for antigen receptor-mediated NF-kB activation. Journal of Immunology 175 7800-7804 Arenas-Sordo
ML< Vallejo-Vega B, Hernandez-Zamora E, Galvez-Rosas A and Montoya-Perez LA
(2005) Incontinentia pigmenti (IP2): Familiar case report with affected men. Med
Oral Patol Oral Cir Bucal 10 E122-E129 Arenz
A, Hellweg CE, Stojicic N, Baumstark-Khan C and Grotheer HH (2006) Gene
expression modulation in a549 human lung cells in response to
combustion-generated nano-sized particles. Arenzana-Seisdedos
F, Thompson J, Rodriguez MS, Bachelerie F, Thomas D and Hay RT (1995)
Inducible nuclear expression of newly synthesized IkBa negatively regulates
DNA-binding and transcriptional activities of NF-kB. Molecular and Cellular
Biology 15 2689-2696 Arenzana-Seisdedos
F, Turpin P, Rodriguez M, Thomas D, Hay RT, Virelizier J-L and Dargemont C
(1997) Nuclear localization of IkBa. Journal of Cell Science 110 369-378 Arganaraz GA, Konno AC, Perosa SR, Santiago JF, Boim MA, Vidotti DB, Varella PP, Costa LG, Canzian M, Porcinatto MA, Yacubian EM, Sakamoto AC, Carrete Jr H, Centeno RS, Amado D, Cavalheiro EA, Junior JA and Mazzacoratti MD (2008) The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis. Epilepsia in press Argueta JG, Shiota S, Yamaguchi N, Masuhiro Y and Hanazawa S (2006) Induction of Porphyromonas gingivalis GroEL signaling via binding to Toll-like receptors 2 and 4. Oral Microbiology and Immunology 21 245-251
Argueta-Donohue J, Carrillo N, Valdes-Reyes L, Zentella A, Aguirre-Garcia M, Becker I and Gutierrez-Kobeh L (2008) Leishmania mexicana: Participation of NF-kB in the differential production of IL-12 in dendritic cells and monocytes induced by lipophosphoglycan (LPG). Experimental Parastitology in press
Ariga
A, Namekawa JI, Matsumoto N, Inoue JI and Umezawa K (2002) Inhibition of
TNF-a-induced nuclear translocation and activation of NF-kB by
dehydroxymethylepoxyquinomicin. Journal of Biological Chemistry 277 24625-24630
Arikan E, Guldiken S, Altun BU, Kara M and Tugrul A (2005) Exacerbations of
Graves' disease after unilateral adrenalectomy for Cushing's syndrome. J
Endocrinol Invest 27 574-576
Arima
N, Kuziel WA, Grdina TA and Greene WC (1992) IL-2-induced signal transduction
involves the activation of nuclear NF-kB expression. Journal of Immunology 149
83-91 Arima
N, Matsushita K, Obata H, Ohtsubo H, Fujiwara H, Arimura K, Kukita T, Suruga
Y, Wakamatsu S, Hidaka S and Tei C (1999) NF-kB involvement in the activation
of primary adult T-cell leukemia cells and its clinical implications.
Experimental Hematology 27 1168-1175 Arima
N, Molitor JA, Smith MR, Kim JH, Daitoku Y and Greene WC (1991) Human T-cell
leukemia virus type I Tax induces expression of the Rel-related family of kB
enhancer-binding proteins: evidence for a pretranslational component of
regulation. Journal of Virology 65 6892-6899 Arimura Y, Vang Y, Tautz L, Williams S and Mustelin T (2008) TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses. Molecular Immunology in press Arita S, Baba E, Shibata Y, Niiro H, Shimoda S, Is0obe T, Kusaba H, Nakano S and Harada M (2008) B cell activation regulates exosomal HLA production. European Journal of Immunology 38 1423-1434 Ariyoshi W, Takahashi T, Kanno T, Ichimiya N, Shinmyouzu K, Takano H, Koseki T and Nishihara T (2008) Heparin inhibits osteoclastic differentiation and function. Journal of Cellular Biochemistry in press Arita M, Bianchini F, Aliberti J, Sher A, Chiang N, Hong S, Yang R, Petasis NA and Serhan CN (2005) Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. Journal of Experimental Medicine 201 713-722 Arita M, Ohira T, Sun YP, Elangovan S, Chiang N and Serhan CN (2007) Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation. Journal of Immunology 178 3912-3917 Ariumi
Y, Kaida A, Hatanaka M and Shimotohno K (2001) Functional cross-talk of HIV-1
Tat with p53 through its C-terminal domain. Biochemical and Biophysical
Research Communications 287 556-561 Ariumi Y, Kaida A, Lin JY, Hirota M, Masui O, Yamaoka
S, Taya Y and Shimotohno K (2000) HTLV-1 tax oncoprotein represses the
p53-mediated trans-activation function through coactivator CBP sequestration.
Oncogene 19 1491-1499 Arlt
A, Gehrz A, Muerkoster S, Vorndamm J, Kruse ML, Folsch UR and Schafer H (2003)
Role of NF-kB and Akt/PI3K in the resistance of pancreatic carcinoma cell
lines against gemcitabine-induced cell death. Oncogene 22 3243-3251 Arlt
A, Kruse ML, Breitenbroich M, Gehrz A, Koc B, Minkenberg J, Folsch UR and
Schafer H (2003) The early response gene IEX-1 attenuates NF-kB activation in
293 cells, a possible counter-regulatory process leading to enhanced cell
death. Oncogene 22 3343-3351 Arlt
A, Vorndamm J, Breitenbroich M, Folsch U, Kalthoff H, Schmidt WE, Schafer H
(2001) Inhibition of NF-kB
sensitizes human pancreatic carcinoma cells to
apoptosis induced by etoposide (VP16) or doxorubicin. Oncogene 20 859-868 Armato RJ (2007) Heat-shock protein-peptide complex-96 for the treatment of cancer. Expert Opinion on Biological Therapy 7 1267-1273 Armistead
HS (2001) Taking the HIV factory tour. Annals of Tropical Paediatrics 21 191-194 Armstead
VE, Opentanova IL, Minchenko AG and Lefer AM (1999) Tissue factor expression
in vital organs during murine traumatic shock: role of transcription factors
AP-1 and NF-kB. Anesthesiology 91 1844-1852 Armstrong
AP, Tometsko ME, Glaccum M, Sutherland CL, Cosman D and Dougall WC (2002) A
rank/TRAF6-dependent signal transduction pathway is essential for osteoclast
cytoskeletal organization and resorptive function. Journal of Biological Chemistry
277 44347-44356 Armstrong MB, Bian X, Liu Y, Subramanian C, Ratanaproeksa AB, Shao F, Yu VC, Kwok RP, Opipari Jr AW and Castle VP (2006) Signaling from p53 to NF-kB determines the chemotherapy responsiveness of neuroblastoma. Neoplasia 8 964-974 Armstrong S, Korcok J, Sims SM and Dixon SJ (2007) Activation of transcription factors by extracellular nucleotides in immune and related cell types. Purinergic Signaling 3 59-69 Armstrong SJ, Wiberg M, Terenghi G adn Kingham PJ (2008) Laminin activates NF-kB in Schwann cells to enhance neurite outgrowth. Neuroscience Letters in press Arnalich F, Garcia-Palomero E, Lopez J, Jimenez M,
Madero R, Renart J, Vazquez JJ and Montiel C (2000) Predictive value of
nuclear factor kB activity and plasma cytokine levels in patients with sepsis.
Infection and Immunity 68 1942-1945 Arnold
NB, Ketterer K, Kleeff J, Friess H, Buchler MW and Korc M (2004) Thioredoxin
is downstream of smad7 in a pathway that promotes growth and suppresses
cisplatin-induced apoptosis in pancreatic cancer. Cancer Research 64 3599-3606 Arnold R, Konig B, Werchau H and Konig W (2004) Respiratory syncytial virus deficient in soluble G protein induced an increased proinflammatory response in human lung epithelial cells. Virology 330 384-397 Arnold R, Liou J, Drexler HC, Weiss A and Kiefer F (2001) Caspase-medaited cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkB into an inhibitor of NFkB. Journal of Biological Chemistry 276 14675-14684 Arnold R, Patzak IM, Neuhaus B, Vancauwenbergh S, Veillette A, Van Lint J and Kiefer F (2005) Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase d1. Molecular and Cellular Biology 25 2364-2383 Arnold
R, Rihoux J and Konig W (1999) Cetirizine counter-regulates interleukin-8
release from human epithelial cells (A549). Clin Exp Allergy 29
1681-1691 Aronica
MA, Mora AL, Mitchell DB, Finn PW, Johnson JE, Sheller JR and Boothby MR
(1999) Preferential role for NF-kB/Rel signaling in the type 1 but not type 2
T cell-dependent immune response in vivo. Journal of Immunology 163 5116-5124
Aronson
D (2002) Potential role of advanced glycosylation end products in promoting
restenosis in diabetes and renal failure. Medical Hypotheses 59 297 Arredondo J, Chernyavsky AI and Grando SA (2006) Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells. Cancer Biology & Therapy 5 511-517 Arredono J, Chernyavsky AI and Grando SA (2006) The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells. Journal of Cancer Research and Clinical Oncology 132 653-663 Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE and Grando SA (2007) Receptor-mediated tobacco toxicity: alterations of the NF-kB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes. Life Sciences in press Arredondo
J, Chernyavsky AI, Marubio LM, Beaudet AL, Jolkovsky DL, Pinkerton KE and
Grando SA (2005) Receptor-mediated tobacco toxicity: regulation of gene
expression through alpha3beta2 nicotinic receptor in oral epithelial cells.
American Journal of Pathology 166 597-613 Arron JR, Pewzner-Jung Y, Walsh MC, Kobayashi T and Choi Y (2002) Regulation
of the subcellular localization of tumor necrosis factor receptor-associated
factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling. Journal of
Experimental Medicine 196 923-934 Arruda MA, Rossi AG, De Freitas MS, Barja-Fidalgo C and Graca-Souza AV (2004)
Heme inhibits human neutrophil apoptosis: involvement of phosphoinositide
3-kinase, MAPK, and NF-kB. Journal of Immunology 173 2023-2030 Arsura
M, FitzGerald MJ, Fausto N and Sonenshein GE (1997) NF-kB/Rel blocks
transforming growth factor-b1-induced apoptosis of murine hepatocyte cell
lines. Cell Growth & Differentiation 8 1049-1059 Arsura
M, Lee H, Wu M, Duyao M, Buckler AJ and Sonenshein GE (1995) Role of
Rel-related factors in control of c-myc
gene transcription in receptor mediated apoptosis of the murine B cell WEHI231
line. Journal of Experimental Medicine 181 1169-1177 Arsura
M, Mercurio F, Oliver AL, Thorgeirsson SS and Sonenshein GE (2000) Role of the
IkB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat
liver epithelial cells. Molecular and Cellular Biology 20 5381-5391 Arsura
M, Panta GR, Bilyeu JD, Cavin LG, Sovak MA, Oliver AA, Factor V, Heuchel R,
Mercurio F, Thorgeirsson SS and Sonenshein GE (2003) Transient activation of
NF-kB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD
signaling and apoptosis: implications in liver tumor formation. Oncogene 22
412-425 Arthur JS (2008) MSK activation and physiological roles. Frontiers in Bioscience 13 5866-5879 Artis D, Kane CM, Fiore J, Zaph C, Shapira S, Joyce K, Macdonald A, Hunter C,
Scott P and Pearce EJ (2005) Dendritic cell-intrinsic expression of NF-kB1 is
required to promote optimal Th2 cell differentiation. Journal
of Immunology 174 7154-7159 Aruda MA, Barcellos-de-Souza P, Sampaio AL, Rossi AG, Graca-Souza AV and Barja-Fidalgo C (2007) NADPH oxidase-derived ROS: Key modulators of heme-induced mitochondrial stability in human neutrophils. Experimental Cell Research 312 3939-3948 Arvelo
MB, Badrichani AZ, Stroka DM, Grey ST, Bach FH and Ferran C (1999) A novel
function for A20 in smooth muscle cells: inhibition of activation and
proliferation. Transplant Proc 31 858-859 Arya J, Finlayson CA, Shames BD, Harken AH and Anderson
BO (2000) Stimulated apoptosis as an anti-neoplastic strategy. Surgery 127
366-369 Asaad NY and Sadek GS (2006) Pulmonary cryptosporidiosis: role of COX2 and NF-kB. APMIS 114 682-689 Asaba K, Iwasaki Y, Asai M, Yoshida M, Nigawara T, Kambayashi M and Hashimoto K (2006) High glucose activates pituitary proopiomelanocortin gene expression: possible role of free radical-sensitive transcription factors. Diabetes and Metabolism Research Reviews in press
Asai T, Nakatani T, Tamada S, Kuwabara N, Yamanaka S, Tashiro K, Nakao T,
Komiya T, Okamura M, Kim S, Iwao H and Miura K (2003) Activation of
transcription factors AP-1 and NF-kB in chronic cyclosporine A nephrotoxicity:
role in beneficial effects of magnesium supplementation. Transplantation 75
1040-1044 Asai Y, Hashimoto M and Ogawa T (2003) Treponemal glycoconjugate inhibits Toll-like receptor ligand-induced cell activation by blocking LPS-binding protein and CD14 functions. European Journal of Immunology 33 3196-3204 Asai Y, Hashimoto M, Fletcher HM, Miyake K, Akira S and Ogawa T (2005) Lipopolysaccharide preparation extracted from Porphyromonas gingivalis lipoprotein-deficient mutant shows a marked decrease in Toll-like receptor 2-mediated signaling. Infection and Immunity 73 2157-2163 Asai Y, Hirokawa Y, Niwa K and Ogawa T (2003) Osteoclast
differentiation by
human osteoblastic cell line SaOS-2 primed with bacterial lipid A. FEMS
Immunol Med Microbiol 38 71-79 Asamitsu K, Tetsuka T, Kanazawa S and Okamoto T (2003) RING finger protein AO7
supports the NF-kB-mediated transcription by interacting with the
transactivation domain of p65 subunit. Journal of Biological Chemistry 278
26879-26887 Asano S, Rice KM, Kakarla S,Katta A, Desai DH, Walker EM, Wehner P and Blough ER (2007) Aging influences multiple indices of oxidative stress in the heart of the Fischer 344/NNia x Brown Norway/BiNia rat. Redox Reports 12 167-180 Asano T, Yao Y, Zhu J, Li D, Abbruzzese JL and Reddy SA (2005) The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kB and c-Myc in pancreatic cancer cells. Oncogene 23 8571-5180 [Erratum in: Oncogene (2005) 24 4320]
Asanuma M and Cadet JL (1998) Methamphetamine-induced increase in striatal
NF-kB DNA-binding activity is attenuated in superoxide dismutase transgenic
mice. Molecular Brain Research 60 305-309 Asehnoune K, Strassheim D, Mitra S, Kim JY and Abraham E (2004) Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kB. Journal of Immunology 172 2522-2529 Asehnoune K, Strassheim D, Mitra S, Yeol Kim J and Abraham E (2005) Involvement of PKCalpha/beta in TLR4 and TLR2 dependent activation of NF-kB. Cellular Signaling 17 385-394 Ash SC, Yang DQ and Britt DE (2008) LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells. Biochemical and Biophysical Research Communications in press Ashburner
BP, Shackelford RE, Baldwin Jr AS and Paules RS (1999) Lack of involvement
of ataxia telangiectasia mutated (ATM) in regulation of Nuclear Factor-kB
(NF-kB) in human diploid fibroblasts. Cancer Research 59 5456-5460 Ashburner BP, Westerheide
SD and Baldwin Jr. AS (2001) The p65 (Rel A) Subunit of NF-kB interacts with
the Histone Deactylase (HDAC) corepressors HDAC1 and HDAC2 to negatively
regulate gene expression. Molecular and Cellular Biology 21 7065-7077 Ashida H, Kihara K, Nonaka Y, Fukuda I, Shiotani B and Hashimoto T (2001) The heterocyclic amine, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole induces apoptosis in cocultures of rat parenchymal and nonparenchymal liver cells. Toxicology and Applied Pharmacology 177 59-67 Ashikawa K, Majumdar S, Banerjee S, Bharti AC,
Shishodia S and Aggarwal BB (2002) Piceatannol inhibits TNF-induced NF-kB
activation and NF-kB-mediated gene expression through suppression of IkBa
kinase and p65 phosphorylation. Journal of Immunology 169 6490-6497
Ashizawa M, Miyazaki M, Abe K, Furusu A, Isomoto H, Harada T, Ozono Y, Sakai
H, Koji T and Kohno S (2003) Detection of nuclear factor-kB in IgA nephropathy
using Southwestern histochemistry. American Journal of Kidney Disease 42 76-86 Ashley
C, Pastushok L, McKenna S, Ellison MJ and Xiao W (2002) Roles of mouse UBC13
in DNA postreplication repair and Lys63-linked ubiquitination. Gene 285
183-191 Ashraf
SI and Ip TY (2001) The Snail family regulates neuroblast expression of insecuteable
and string, genes involved in asymmetry and cell division in Drosophila.
Development 128 4757-4767 Ashraf
SI, Hu X, Roote J and Ip YT (1999) The mesoderm determinant Snail collaborates
with related zinc-finger proteins to control Drosophila neurogenesis.
EMBO Journal 18 6426-6438 Ashworth T and Roy AL (2007) TFII-I controls B cell proliferation via regulating NF-kB. Journal of Immunology 178 2631-2635
Asin S, Bren GD, Carmona EM, Solan NJ and Paya CV
(2001) NF-kB cis-acting motifs of the human immunodeficiency virus
(HIV) long terminal repeat regulate HIV transcription in human macrophages.
Journal of Virology 75 11408-11416 Asin
S, Taylor JA, Trushin S, Bren G and Paya CV (1999) IKK mediates NF-kB
activation in human immunodeficiency virus-infected cells. Journal of Virology
73 3893-3903
Asirvatham AJ, Gregorie CJ, Hu Z, Magner WJ and Tomasi TB (2007) MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components. Molecular Immunology in press Asoh S, and Ohta S (2007) PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes. Advances in Drug Delivery Reviews in press Aspalter
RM, Eibl MM and Wolf HM (2007) Defective T-cell activation caused by
impairment of the TNF receptor 2 costimulatory pathway in common variable
immunodeficiency. Asschert
JG, Vellenga E, Ruiters MH and de Vries EG (1999) Regulation of spontaneous
and TNF/IFN-induced IL-6 expression in two human ovarian-carcinoma cell lines.
International Journal of Cancer 82 244-249 Assenat E, Gerbal-Chaloin S, Larrey D, Saric J, Fabre JM, Maurel P, Vilarem MJ and Pascussi JM (2004) Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. Hepatology 40 951-960 Assenat E, Maurel P, Vilarem MJ, Pascussi JM and Gerbal-Chaoloin S (2006) Is nuclear factor kB the missing link between inflammation, cancer and alteration in hepatic drug metabolism in patients with cancer? European Journal of Cancer in press Asso-Bonnet
M, Feulillard J, Ferreira V, Bissières P, Tarantino N, Körner M and Raphael
M (1998) Relationship between IkBa constitutive expression, TNFa synthesis,
and apoptosis in EBV-infected lymphoblastoid cells. Oncogene 17 1607-1615 Assogba
BD, Paik NW and Rho HM (2004) Transcriptional activation of gammaherpesviral
oncogene promoters by the hepatitis B viral X protein (HBx). DNA Cell Biology
23 141-148 Agayde VD, Jasiulionis MG, Cortez M and Yoshida N (2008) A recombinant protein based on Trypanosoma cruzi surface molecule gp82 induces apoptotic cell death in melanoma cells. Melanoma Research 18 172-183 Atchinson
ML and Perry RP (1987) The role of the k enhancer and its binding factor NF-kB
in the developmental regulation of k gene transcription. Cell 48 121-128 Atherton PJ, Higginson JM, Singh J and Wackerhage H (2004) Concentrations of signal transduction proteins exercise and insulin responses in rat extensor digitorum longus and soleus muscles. Molecular and Cellular Biochemistry 261 111-116 Aktas O, Prozorovski T, Smorodchenko A, Savaskan NE, Lauster R, Kloetzel PM, Infante-Duarte C, Brocke S and Zipp F (2004) Green tea epigallocatechin-3-gallate mediates T cellular NF-kB inhibition and exerts neuroprotection in autoimmune encephalomyelitis. Journal of Immunology 173 5794-5800 Atkins
KB, Lodhi IJ, Hurley LL and Hinshaw DB (2000) N-acetylcysteine and endothelial
cell injury by sulfur mustard. J Appl Toxicol 20 Suppl 1 S125-S128 Atreya I, Atreya R and Neurath MF (2008) NF-kB in inflammatory bowel disease. Journal of Internal Medicine 263 591-596 Attar
RM, Caamaño J, Carrasco D, Iotsova V, Ishikawa H, Ryseck R-P, Weih F and
Bravo R (1997) Genetic approaches to study Rel/NF-kB/IkB function in mice.
Seminars in Cancer Biology (TD Gilmore, ed) 8 93-101 Attar
RM, Macdonald-Bravo H, Durham SK and Bravo R (1998) Expression of a
constitutively active IkBbeta in T cells of transgenic mice: persistent NF-kB
activity is required for T-cell immune responses. Molecular and Cellular
Biology 18 477-487 Au PY and Yeh WC (2007) Physiological roles and mechanisms of signaling by TRAF2 and TRAF5. Advances in Experimental Medicine and Biology 597 32-47 Au PYB, Martin N, Chau H, Moemeni B, Chia M, Liu F-F, Minden M and Yeh W-C (2005) The oncogene PDGF-B provides a key switch from cell death to survival induced by TNF. Oncogene 24 3196-3205 Au-Yeung
KK, Woo CW, Sung FL, Yi JC, Siow YL and O K (2003) Hyperhomocysteinemia
activates Nuclear Factor-kB in endothelial cells via oxidative stress.
Circulation Research 94 28-36 Aubrecht
J, Narla RK, Ghosh P, Stanek J and Uckun FM (1999) Molecular genotoxicity
profiles of apoptosis-inducing vanadocene complexes. Toxicol Appl Pharmacol
154 228-235 Auch
CJ, Dasgupta S, Jana M, Liu X and Pahan K (2002) Double-stranded RNA induces
nitric oxide synthase in human astrocytes. Journal of Neurochemistry 81 54-56 Audette M, Larouche
L, Lussier I and Fugere N (2001) Stimulation of the ICAM-1 gene transcription
by the peroxovanadium compound [bpV(Pic)] involves STAT-1 but not NF-kB
activation in 293 cells. European Journal of Biochemistry 268 1828-1836 Aune
TM, Mora AL, Kim S, Boothby M and Lichtman AH (1999) Costimulation reverses
the defect in IL-2 but not effector cytokine production by T cells with
impaired IkBa degradation. Journal of Immunology 162 5805-5812 Auphan
N, DiDonato JA, Rosette C, Helmberg A and Karin M (1995) Immunosuppression by
glucocorticoids: inhibition of NF-kB activity through induction of IkB
synthesis. Science 270 286-290 Auphan
N, Ghosh S, Flavell RA and Schmitt-Verhulst AM (1999) Differential
requirements for NF-kB and AP-1 trans-activation in response to minimal TCR
engagement by a partial agonist in naive CD8 T cells. Journal of Immunology
163 5219-5227 Aupperle
K, Bennett B, Han Z, Boyle D, Manning A and Firestein G (2001) NF-kB
regulation by IkB kinase-2 in rheumatoid arthritis synoviocytes. Journal of
Immunology 166 2705-2711 Aupperle
KR, Bennett BL, Boyle DL, Tak PP, Manning AM and Firestein GS (1999) NF-kB
regulation by IkB kinase in primary fibroblast-like synoviocytes. Journal of
Immunology 163 427-433 Auwardt
RB, Mudge SJ, Chen CG and Power DA (1998) Regulation of nuclear factor kB by
corticosteroids in rat mesangial cells. Journal of the American Society of
Nephrology 9 1620-1628 Avalos
BR, Hunter MG, Parker JM, Celeski SK, Druker BJ, Corey SJ and Mehta VB (1995)
Point mutations in the conserved box 1 region inactivate the human granulocyte
colony-stimulating factor receptor for growth signal transduction and tyrosine
phosphorylation of p75 c-rel. Blood 85 3117-3126 Avet-Rochex A, Bergeret E, Attree I, Meister M and Fauvarque MO (2005) Suppression of Drosophila cellular immunity by directed expression of the ExoS toxin GAP domain of Pseudomonas aeruginosa. Cell Microbiol 7 799-810 Avila
A, Silverman N, Diaz-Meco MT and Moscat J (2002) The Drosophila atypical
protein kinase C-Ref(2)P complex constitutes a conserved module for signaling
in the Toll pathway. Molecular and Cellular Biology 22 8787-8795 Avramidou A, Kroczek C, Lang C, Schuh W, Jack HM and Mielenz D (2007) The novel adaptor protein Swiprosin-1 enhances BCR signals and contributes to BCR-induced apoptosis. Cell Death and Differentiation in press Aw TY
(1999) Molecular and cellular responses to oxidative stress and changes in
oxidation-reduction imbalance in the intestine. American Journal of Clinical
Nutrition 70 557-565 Awad HA, Zhang X, Reynolds DG, Guldberg RE, O'Keefe RJ and Schwarz EM (2007) Recent advances in gene delivery for structural bone allografts: a review. Tissue Engineering in press Awad
S, Yokozeki H, Miyazaki Y, Igawa K, Minatohara K, Satoh T and Nishioka K
(2002) Glucocorticoids induced the production and gene expression of IL-1a
through AP-1 and partially NF-kB activation in murine epidermal cells. J Med
Dent Sci 49 27-35 Axelsson
J, Karadottir R and Karlsson MM (2002) Differences in prevalence of seasonal
affective disorder that are not explained by either genetic or latitude
differences. International Journal of Circumpolar Health 61 17-20
Aya K, Alhawagri M, Hagen-Stapleton A, Kitaura H, Kanagawa O and Novack DV
(2005) NF-kB-inducing kinase controls lymphocyte and osteoclast activities in
inflammatory arthritis. Journal of Clinical Investigation 115 1848-1854 Ayala GE, Dai H, Ittmann M, Li R, Powell M, Frolov A, Wheeler TM, Thompson TC and Rowley D (2004) Growth and survival mechanisms associated with perineural invasion in prostate cancer. Cancer Research 64 6082-6090
Ayasolla K, Khan M, Singh AK and Singh I (2004) Inflammatory mediator and
beta-amyloid (25-35)-induced ceramide generation and iNOS expression are
inhibited by vitamin E. Free Radic Biol Med 37 325-338 Ayyar S, Pistillo D, Caleja M, Brookfield A, Gittins K, Goldstone C adn Simpson P (2007) NF-kB/Rel-mediated regulation of the neural fate in Drosophila. PLOS ONE 2 e1178 Ayyavoo
V, Mahboubi A, Mahalingam S, Ramalingam R, Kudchodkar S, Williams WV, Green DR
and Weiner DB (1997) HIV-1 Vpr suppresses immune activation and apoptosis
through regulation of nuclear factor kB. Nature Medicine 3 1117-1123
Azevedo-Martins AK, Lortz S, Lenzen S, Curi R, Eizirik DL and Tiedge M (2003)
Improvement of the mitochondrial antioxidant defense status prevents
cytokine-induced nuclear factor-kB activation in insulin-producing cells.
Diabetes 52 93-101 Azim AC, Wang X, Park GY, Sadikot RT, Cao H, Mathew B, Atchinson M, van Breemen RB, Joo M and Christman JW (2007) NF-kB-inducing kinase regulates cyclooxygenase 2 gene expression in macrophages by phosphorylation of PU.1. Journal of Immunology 179 7868-7875
Aziz SM, Torborek M, Hennig B, Endean E and Lipke DW (1998) Polyamine
regulatory processes and oxidative stress in monocrotaline-treated pulmonary
artery endothelial cells. Cell Biology International 21 801-812
Azoitei N,
Brey A, Busch T, Fulda S, Adler G and Seufferlein T (2007)
Thirty-eight-negative kinase 1 (TNK1) facilitates TNFa-induced apoptosis by
blocking NF-kB activation. Azoitei N, Wirth T and Baumann B (2005) Activation of the IkB kinase complex is sufficient for neuronal differentiation of PC12 cells. Journal of Neurochemistry 93 1487-1501 Azran I, Jeang KT and Aboud M (2005) High levels of cytoplasmic HTLV-1 Tax mutant proteins retain a Tax-NF-kB-CBP ternary complex in the cytoplasm. Oncogene 24 4521-4530 Azran I, Schavinsky-Khrapunsky Y and Aboud M (2004) Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity. Retrovirology 13 20 Azran-Shaish I, Tabakin-Fix Y, Huleihel M, Bakharnashivili M and Aboud M (2008) HTLV-1 Tax-induced NF-kB activation is synergistically enhanced by 12-O-tetradecanoylphorbol-13-acetate: mechanism and implications for Tax oncogenicity. Journal of Molecular Medicine in press Azuma
H, Tomita N, Kaneda Y, Koike H, Ogihara T, Katsuoka Y and Morishita R (2003)
Transfection of NFkB-decoy oligodeoxynucleotides using efficient
ultrasound-mediated gene transfer into donor kidneys prolonged survival of rat
renal allografts. Gene Therapy 10 415-425 Azuma
M, Aota K, Tamatani T, Motegi K, Yamashita T, Harada K, Hayashi Y and Sato M
(2000) Suppression of tumor necrosis factor alpha-induced matrix
metalloproteinase 9 production by the introduction of a super-repressor form
of inhibitor of nuclear factor kBa complementary DNA into immortalized human
salivary gland acinar cells. Prevention of the destruction of the acinar
structure in Sjogren’s syndrome salivary glands. Arthritis and Rheumatism 43
1756-1767 Azuma M, Ashida Y, Tamatani T, Motegi K, Takamaru N, Ishimaru N, Hayashi Y and Sato M (2006) Cepharanthin, a Biscoclaurine alkaloid, prevents destruction fo acinar tissues in murine Sjogren's syndrome. Journal of Rheumatology 33 912-920 Azuma M, Matsuo A, Fujimoto Y, Kukase K, Hazeki K, Hazeki O, Matsumoto M and Seya T (2007) Inhibition of lipid A-mediated type I interferon induction by Bactericidal/permeability-increasing protein (BPI). Biochemical and Biophysical Research Communications in press Azuma
M, Motegi K, Aota K, Yamashita T, Yoshida H and Sato M (1999) TGF-beta1
inhibits NF-kB activity through induction of IkB-a expression in human
salivary gland cells: a possible mechanism of growth suppression by TGF-beta1.
Experimental Cell Research 250 213-222 Azuma
Y and Ohura K (2002) Endomorphins 1 and 2 inhibit IL-10 and IL-12 production
and innate immune functions, and potentiate NF-kB DNA binding in THP-1
differentiated to macrophage-like cells. Scandinavian Journal of Immunology 56
260-269 Azzolina A, Bongiovanni A and Lampiasi N (2003) Substance P induces TNF-alpha
and IL-6 production through NFkB in peritoneal mast cells. Biochimica et
Biophysica Acta 1643 75-83
|