 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Regulation
of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant
Nacystelyn.
Antonicelli F, Brown D, Parmentier M, Drost EM, Hirani N, Rahman I, Donaldson
K, MacNee
|
References Relevant publications listed by the last name of
the first author. Aarenstrup L, Flindt EN, Otkjaer K,Kirkegaard M, Andersen JS and Kristiansen K (2007) HDAC activity is required for p65/RelA-dependent repression of PPARdelta-mediated transactivation in human keratinocytes. Journal of Investigative Dermatology in press
Aarnisalo P, Palvimo JJ and Janne OA (1998) CREB-binding
protein in androgen receptor-mediated signaling. Proceedings of the National
Academy of Sciences USA 95 2122-2127
Aarnisalo
P, Santti H, Poukka H, Palvimo JJ and Janne OA (1999) Transcription activating
and repressing functions of the androgen receptor are differentially
influenced by mutations in the deoxyribonucleic acid-binding
domain.
Endocrinology 140 3097-3105
Abate
A, Oberle S and Schroder H (1998) Lipopolysaccharide-induced expression of
cyclooxygenase-2 in mouse macrophages is inhibited by chloromethylketones and
a direct inhibitor of NF-kB translocation. Prostaglandins and Other Lipid Mediators
56 277-290 Abate
A, Yang G, Dennery PA, Oberle S and Schroder H (2000) Synergistic inhibition
of cyclooxygenase-2 expression by vitamin E and aspirin. Free Radical Biology
and Medicine
29 1135-1142 Abate DA, Watanabe S and Mocarski ES (2004) Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response. Journal of Virology 78 10995-11006 Abayomi EA, Sissolak G and Jacobs P (2007) Use of novel proteosome inhibitors as a therapeutic strategy in lymphomas current experience and emerging concepts. Transfusion and Apheresis Science 37 85-92 Abbadie
C, Kabrun N, Bouali F, Smardova J, Stéhelin D, Vandenbunder B and Enrietto PJ
(1993) High levels of c-rel
expression are associated with programmed cell death in the developing avian
embryo and in bone marrow cells in vitro. Cell 75 899-912 Abbott DW, Wilkins A, Asara JM and Cantley LC (2004) The Crohn's Disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Current Biology 14 2217-2227 Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA nad Cantley LC (2007) Coordinate regulation of Toll-like Receptor and NOD2 signaling by K63-linked polyubiquitin chains. Molecular and Cellular Biology inpress Abbott
KL, Loss JR 2nd, Robida AM and Murphy TJ (2000) Evidence that Galpha(q)-coupled
receptor-induced interleukin-6 mRNA in vascular smooth muscle cells involves
the nuclear factor of activated T cells. Molecular Pharmacology 58 946-953 Abbott KL, Robida AM, Davis ME, Pavlath GK, Camden JM,
Turner JT and Murphy TJ (2000) Differential regulation of vascular smooth
muscle nuclear factor kB by G alpha q-coupled and cytokine receptors. Journal
of Molecular and Cellular Cardiology 32 391-403 Abboud PA, Lahni PM, Page K, Giuliano Jr JS, Harmon K, Dunsmore KE, Wong HR and Wheeler DW (2008) The role of endogenously produced extracellualr HSP72 in mononuclear cell reprogramming in press Abboushi N, El-Hed A, El-Assaad W, Kozhaya L, El-Sabban ME, Bazarbachi A,
Badreddine R, Bielawska A, Usta J and Dbaibo GS (2004) Ceramide inhibits IL-2
production by preventing protein kinase C-dependent NF-kB activation: possible
role in protein kinase C{theta} regulation. Journal of Immunology 173
3193-3200 Abdallah A, Sato H, Grutters JC, Veeraraghavan S, Lympany PA, Ruven HJ, Van
Den Bosch JM, Wells AU, Du Bois RM and Welsh KI (2003) Inhibitor kB-a (IkB-a)
promoter polymorphisms in UK and Dutch sarcoidosis. Genes & Immunity 4
450-454 Abdel-Latif MM, Kelleher D and Reynolds JV (2008) Potential role of NF-kB in esophageal adenocarcinoma: as an emerging molecular target. Journal of Surgical Research in press Abdel-Latif MM, O'Riordan JM, Ravi N, Kelleher D and Reynolds JV (2005) Activated nuclear factor-kB and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy. Dis Esophagus 18 246-252 Abdel-Latif
MM, O'Riordan J, Windle HJ, Carton E, Ravi N, Kelleher D and
Reynolds JV (2004) NF-kB activation in esophageal adenocarcinoma: relationship
to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy. Annals of Surgery 239 491-500 Abdel-Mageed
AB (2003) NF-kB-dependent gene expression of proinflammatory cytokines in T24
cells: possible role in interstitial cystitis. Urology Research 31 300-305 Abdel-Razzak
Z, Garlatti M, Aggerbeck M and Barouki R (2004) Determination of
interleukin-4-responsive region in the human cytochrome P450 2E1 gene
promoter. Biochemical Pharmacology 68 1371-1381 Abdouh
M, Albert PR, Drobetsky E, Filep JG and Kouassi E (2004) 5-HT(1A)-mediated
promotion of mitogen-activated T and B cell survival and proliferation is
associated with increased translocation of NF-kB to the nucleus. Brain Behav
Immun 18 24-34 Abdulla D, Goralski KB, Garcia Del Busto Cano E and Rneton KW (2005) The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during an LPS-induced model of CNS inflammation. Drug Metabolism and Disposition 33 1521-1531 Abdulla D and Renton KW (2005) beta-Adrenergic receptor modulation of the
LPS-mediated depression in CYP1A activity in astrocytes. Biochemical
Pharmacology 69 741-750 Abe JL (2007) Role of PKCs and NF-kB activation in myocardial inflammation: Enemy or ally? Journal of Molecular and Cellular Cardiology in press Abe K, Whitehead IP, O'Bryan JP and Der CJ (1999) Abe M, Takiguchi Y, Ichimaru S, Tsuchiya K and Wada K (2008) Comparison of the protective effect of N-acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury. Journal of Pharmacological Sciences 106 571-577 Abe M, Takiguchi Y, Ichimaru S, Tsuchiya K and Wada K (2008) Different effect of acute treatment with rosiglitazone on rat myocardial ischemia/reperfusion injury by administration method. European Journal of Pharmacology in press Abe M, Tanaka Y, Saito K, Shirakawa F, Koyama Y, Goto S and Eto S (1997)
Regulation of interleukin (IL)-1beta gene transcription induced by IL-1beta in
rheumatoid synovial fibroblast-like cells, E11, transformed with simian virus
40 large T antigen. Journal of Rheumatology 24 420-429 Aberle H, Bauer A, Stappert J, Kispert A and Kemler R (1997) b-catenin is
a target for the ubiquitin-proteasome pathway. EMBO Journal 16 3797-3804 Abeyama K, Eng W, Jester JV, Vink AA, Edelbaum D, Cockerell CJ,
Bergstresser PR, Takashima A (2000) A role for NF-kB-dependent gene
transactivation in sunburn. Journal of Clinical Investigation 105 1751-1759 Abiru S, Nakao K, Ichikawa T, Migita K, Shigeno M, Sakamoto M, Ishikawa H,
Hamasaki K, Nakata K and Eguchi K (2002) Aspirin and NS-398 inhibit hepatocyte
growth factor-induced invasiveness of human hepatoma cells. Hepatology 35
1117-1124 Abou-Merhi
R, Khoriaty R, Arnoult D, El Hajj H, Dbouk H, Munier S, El-Sabban ME, Hermine
O, Gessain A, de The H, Mahieux R and Bazarbachi A (2007) PS-341 or a
combination of arsenic trioxide and interferon-alpha inhibit growth and induce
caspase-dependent apoptosis in KSHV/HHV-8-infected primary effusion lymphoma
cells. Abraham C and Cho JH (2006) Functional consequences of NOD2 (CARD15) mutations. Inflammatory Bowel Disease 12 641-650 Abraham
DJ, Shiwen X, Black CM, Sa S, Xu Y and Leask A (2000) Tumor necrosis factor
alpha suppresses the induction of connective tissue growth factor by
transforming growth factor-beta in normal and scleroderma fibroblasts. Journal
of Biological Chemistry 275 15220-15225 Abraham E (2000) NF-kB activation. Critical Care Medicine
28
N100-N104 Abraham E, Arcaroli J
and Shenkar R (2001) Activation of extracellular signal-regulated kinases,
NF-kB, and cyclic adenosine 5'-monophosphate response element-binding protein
in lung neutrophils occurs by differing mechanisms after hemorrhage or
endotoxemia. Journal of Immunology 166 522-530 Abraham S, Yaddanapudi K, Thomas S, Damodaran A, Ramireddy B and Manjunath R (2008) Nonclassical MHC-I and Japanese encephalitis virus infection: induction of H-2Q4, H-2T23 and H-2T10. Virus Research in press Abrahams VM, Aldo PB, Murphy SP, Visintin I, Koga K, WIlson G, Romero R, Sharma S and Mor G (2008) TLR6 modulates first trimester trophoblast responses to peptidoglycan. Journal of Immunology 180 6035-6043 Abrams CC, Chapman DA, Silk R, Liverani E and Dixon LK (2008) Domains involved in calcineurin phosphatase inhibition and nuclear localisation in the African swine fever virus A238L protein. Virology in press Abramson J, Licht A and Pecht I (2006) Selective inhibition of the FcvarepsilonRI-induced de novo synthesis of mediators by an inhibitory receptor. EMBO Journal 25 323-334 Abrantes EF, Pires EG, Carvalho AF, Costa FF, Savino W and Reis LF (2003) Identification, structural characterization, and tissue distribution of Tsg-5: a new TNF-stimulated gene. Genes and Immunity 4 298-311 Abreu MT, Arnold ET,
Thomas LS, Gonsky R, Zhou Y, Hu B and Arditi M (2002) TLR4 and MD-2 expression
is regulated by immune-mediated signals in human intestinal epithelial cells.
Journal of Biological Chemistry 277 20431-20437 Abril
E, Mendez RE, Garcia A, Serrano A, Cabrera T, Garrido F and Ruiz-Cabello F
(1996) Characterization of a gastric tumor cell line defective in MHC class I
inducibility by both alpha- and gamma-interferon. Tissue Antigens 47 391-398 Abruzzese RV, Godin D, Burcin M, Mehta V, French M, Li Y, O'Malley BW and
Nordstrom JL (1999) Ligand-dependent regulation of plasmid-based transgene
expression in vivo. Human Gene Therapy 10 1499-1507 Abshagen K, Eipel C, Kalff JC, Menger MD and Vollmar B (2007) Loss of NF-kB activation in Kupffer cell-depleted mice impairs liver regeneration after partial hepatectomy. American Journal of Physiology: Gastrointestinal Liver Physiology in press Abu-Amer
Y (2001) IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition
of NF-kB. Journal of Clinical Investigation 107 1375-1385 Abu-Amer Y, Darwech I and Otero J (2008) Role of the NF-kB axis in immune modulation of osteoclasts and bone loss. Autoimmunity 41 204-211 Abu-Amer
Y, Erdmann J, Alexopoulou L, Kollias G, Ross FP and Teitelbaum SL (2000) Tumor
necrosis factor receptors types 1 and 2 differentially regulate
osteoclastogenesis. Journal of Biological Chemistry 275 27307-27310 Abu-Amer
Y, Ross FP, McHugh KP, Livolsi A, Peyron J-F and Teitelbaum SL (1997) Tumor
necrosis factor-a activation of nuclear transcription factor-kB in marrow
macrophages is mediated by c-Src tyrosine phosphorylation of IkBa. Journal of
Biological Chemistry 273 29417-29423 Abu-Zant A, Jones S, Asare R, Suttles J, Price C, Graham J and Kwaik YA (2007) Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophila. Cellular Microbiology 9 246-264 Abujamra AL, Spanjaard RA, AKinsheye I, Zhao X, Faller DV and Ghosh SK (2005) Leukemia virus long terminal repeat activates NFkB pathway by a TLR3-dependent mechanism. Virology 345 390-403 Acaria
L, Gonzalez B and Castellano B (1998) Stat3 and NF-kB glial expression after
excitotoxic damage to the postnatal brain. Neuroreport 9 2869-2873 Acarin L, Gonzalez B and Castellano B (2000) STAT3 and
NF-kB activation precedes glial reactivity in the excitotoxically injured
young cortex but not in the corresponding distal thalamic nuclei. Journal of Neuropathology
and Experimental Neurology 59 151-163 Acarin
L, Gonzalez B, Castellano B (2001) Acharyya S and Guttridge DC (2007) Cancer cachexia signaling pathways continue to emerge yet much still points to the proteasome. Clinical Cancer Research 13 1356-1361 Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, Baldwin AS and Guttridge DC (2007) Interplay of IKK/NF-kB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. Journal of Clinical Investigation 117 889-901 Achiron A, Feldman A, Mandel M and Gurevich M (2007) Impaired expression of peripheral blood apoptotic-related gene transcripts in acute multiple sclerosis relapse. Annals of the New York Academy of Sciences 1107 155-167 Ackerman H, Udalova I, Hull J and Kwiatkowski D (2002) Evolution of a polymorphic regulatory element in interferon-gamma through transposition and mutation. Molecular Biology and Evolution 19 884-890
Ackerman IV WE, Rovin BH and Kniss DA (2004) Epidermal growth factor and
interleukin-1b utilize divergent signaling pathways to synergistically
upregulate cyclooxygenase-2 gene expression in human amnion-derived WISH
cells. Biology of Reproduction 71 2079-2086 Ackerman IV WE, Zhang XL, Rovin BH and Kniss DA (2005) Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkB signal disruption in human WISH and amnion cells. Biology of Reproduction 73 527-535
Ackermann LW and Denning GM (2004) Nuclear factor-kB contributes to
interleukin-4- and interferon-dependent polymeric immunoglobulin receptor
expression in human intestinal epithelial cells. Immunology 111 75-85
Acquaah-Mensah GK, Kehrer JP and Leslie SW (2002) In utero
ethanol suppresses
cerebellar activator protein-1 and nuclear factor-kB transcriptional
activation in a rat fetal alcohol syndrome model. Journal of Pharmacology
and Experimental Therapy 301
277-283
Acquaviva R, Campisi A, Raciti G, Avola R, Barcellona ML, Vanella A and Li Volti G
(2005) Propofol
inhibits caspase-3 in astroglial cells: role of heme oxygenase-1. Current
Neurovascular Research 2 141-148 Adachi
O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, Sakagami M, Nakanishi K and
Akira S (1998) Targeted disruption of the MyD88 gene results in loss of IL-1-
and IL-18-mediated function. Immunity 9 143-150 Adam D, Kessler U and Kronke M (1995) Cross-linking of the p55 tumor necrosis
factor receptor cytoplasmic domain by a dimeric ligand induces nuclear
factor-kB and mediates cell death. Journal of Biological Chemistry 270
17482-17487 Adam E, Hansen KK, Astudillo Fernandez O, Coulon L, Bex F, Duhant X, Jaumotte E, Hollenberg MD and Jacquet A (2005) The house dust mite allergen DER P 1, unlike DER P 3, stimulates the expression of IL-8 in human airway epithelial cells via a proteinase-activated receptor -2 (PAR2) independent mechanism. Journal of Biological Chemistry 691 6910-6923 Adam
E, Quivy V, Bex F, Chariot A, Collette Y, Vanhulle C, Schoonbroodt S, Goffin
V, Nguyen TL-A, Gloire G, Carrard G, Friguet B, de Launoit Y, Burny A, Bours V,
Piette J and Van Lint C (2003) Potentiation of tumor necrosis factor-induced
NF-kB activation by deacetylase inhibitors is associated with a delayed
cytoplasmic reappearance of IkBa. Molecular and Cellular Biology 23 6200-6209 Adami C, Bianchi R, Pula G and Donato R (2004) S100B-stimulated NO production
by BV-2 microglia is independent of RAGE transducing activity but dependent on
RAGE extracellular domain. Biochimica et Biophysica Acta 1742 169-177 Adams AB, Williams MA, Jones TR, Shirasugi N, Durham MM, Kaech SM, Wherry EJ,
Onami T, Lanier JG, Kokko KE, Pearson TC, Ahmed R and Larsen CP (2003)
Heterologous immunity provides a potent barrier to transplantation tolerance.
Journal of Clinical Investigation 111 1887-1895 Adams
CC and Workman JL (1995) Binding of disparate transcriptional activators to
nucleosomal DNA is inherently cooperative. Molecular and Cellular Biology 15
1405-1421 Adams DS, Nathans R, Pero SC, Sen A and Wakshull E
(2000) Activation of a rel-A/CEBP-beta-related transcription factor heteromer
by PGG-glucan in a murine monocytic cell line. Journal of Cellular Biochemistry 77 221-233 Adams
DS, Pero SC, Petro JB, Nathans R, Mackin WM and Wakshull E (1997) PGG-Glucan
activates NF-kB-like and NF-IL-6-like transcription factor complexes in a
murine monocytic cell line. Journal of Leukocyte Biology 62 865-873 Adams J (2004) The proteasome: a suitable antineoplastic target. Nature Reviews Cancer 4 349-360 Adams
J (2004) The development of proteasome inhibitors as anticancer drugs.
Cancer Cell 5 417-421 Adams V, Nehrhoff B, Spate U, Linke A, Schulze PC, Baur A, Gielen S, Hambrecht
R and Schuler G (2002) Induction of iNOS expression in skeletal muscle by
IL-1beta and NFkB activation: an in vitro and in vivo study. Cardiovascular
Research 54 95-104 Adcock IM (1997) Transcription factors as activators of gene transcription:
AP-1 and NF-kB. Monaldi Arch Chest Dis 52 178-186 Adcock IM, Cosio B, Tsaprouni L, Barnes PJ and Ito K (2005) Redox regulation
of histone deacetylases and glucocorticoid-mediated inhibition of the
inflammatory response. Antioxidants & Redox Signaling 7 144-152 Adcock IM, Lane SJ, Brown CR, Lee TH and Barnes PJ (1995) Abnormal
glucocorticoid receptor-activator protein 1 interaction in steroid-resistant
asthma. Journal of Experimental Medicine 182 1951-1958 Addya S, Shiroto K, Turoczi T, Zhan L, Kaga S, Fukuda S, Surrey S, Duan LJ, Fong GH, Yamamoto F and Maulik N (2005) Ischemic preconditioning-mediated cardioprotection is disrupted in heterozygous Flt-1 (VEGFR-1) knockout mice. Journal of Molecular and Cellular Cardiology 38 345-351 Adelson ME, Martinand-Mari C, Iacono KT, Muto NF and Suhadolnik RJ (1999)
Inhibition of human immunodeficiency virus (HIV-1) replication in SupT1 cells
transduced with an HIV-1 LTR-driven PKR cDNA construct. European Journal of
Biochemistry 264 806-815 Adhikari N, Charles N, Lehmann U and Hall JL (2006) Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury. Current Atherosclerosis Reports 8 252-260 Adhirkari A, Xu M and Chen ZJ (2007) Ubiquitin-mediated activation of TAK1 and IKK. Oncogene. 26 3214-3226
Adib-Conquy M, Adrie C, Moine P, Asehnoune K, Fitting C, Pinsky MR, Dhainaut
JF and Cavaillon JM (2000) NF-kB expression in mononuclear cells of patients with
sepsis resembles that observed in lipopolysaccharide tolerance. American Journal
of Respiratory and Critical Care Medicine 162 1877-1883 Adib-Conquy M and Cavaillon JM (2002) IFNg and GM-CSF
prevent endotoxin tolerance in human monocytes by promoting IRAK expression
and its association to MyD88, and not by modulating TLR4 expression. Journal
of Biological Chemistry 277 27927-27934 Adib-Conquy
M, Petit AF, Marie C, Fitting C and Cavaillon JM (1999) Paradoxical priming
effects of IL-10 on cytokine production. International Immunology 11 689-698 Adler V and Kraft AS (1995) Regulation of AP-3 enhancer activity during
hematopoietic differentiation. Journal of Cell Physiology 164 26-34 Adolph KW, Liska DJ and Bornstein P (1997) Analysis of the promoter and transcription start sites of the human thrombospondin 2 gene (THBS2). Gene 193 5-11 Adorini L (2005) Intervention in autoimmunity: The potential of vitamin D receptor agonists. Cellular Immunology 233 115-124 Adorini L, Penna G, Giarratana N, Roncari A, Amuchastegui S, Daniel KC and
Uskokovic M (2004) Dendritic cells as key targets for immunomodulation by
Vitamin D receptor ligands. Journal of Steroid Biochemistry and Molecular
Biology 89-90 437-441 Adriaenssens E, Mougel A, Goormachtigh G, Loing E, Fafeur V, Auriault C and
Coll J (2004) A novel dominant-negative mutant form of Epstein-Barr virus
latent membrane protein-1 (LMP1) selectively and differentially impairs LMP1
and TNF signaling pathways. Oncogene 23 2681-2693 Adzic M, Niciforovic A, Vucic V, Neskovic-Konstantinovic Z, Spasic SD, Jones DR, Radjcic MB and Spasic MB (2006) Systemic NF-kB activation in blood cells of breast cancer patients. Redox Reports 11 39-44 Adzic M, Niciforovic A, Zaric B, Neskovic-Konstantinovic Z, Spasic SD, Jones DR, and Radjcic MB (2008) Cell culture conditions potentiate differences in the response to ionising radiation of peripheral blood leukocytes isolated from breast cancer patients and healthy subjects. Redox Reports 13 17-22 Aeberli D, Yang Y, Mansell A, Santos L, Leech M and Morand EF (2006) Endogenous macrophage migration inhibitory factor modulates glucocorticoid sensitivity in macrophages via effects on MAP kinase phosphatase-1 and p38 MAP kinase. FEBS Letters 580 974-981 Afaq F, Ahmad N and Mukhtar H (2003) Suppression of UVB-induced
phosphorylation of mitogen-activated protein kinases and nuclear factor kB by
green tea polyphenol in SKH-1 hairless mice. Oncogene 22 9254-9264 Afford SC, Ahmed-Choudhury
J, Randhawa S, Russell C, Youster J, Crosby HA,
Eliopoulos A, Hubscher SG,
Young LS and Adams DH (2001) CD40 activation-induced, Fas-dependent apoptosis
and NF-kB/AP-1 signaling in human intrahepatic biliary epithelial cells. FASEB
Journal 15 2345-2354 Afonso PV, Ozden S, Prevost MC, Schmitt C, Seilhean D, Weksler B, Couraud PO, Gessain A, Romero IA and Ceccaldi PE (2007) Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization. Journal of Immunology 179 2576-2583 Aga M, Johnson CJ, Hart
AP, Guadarrama AG, Suresh M, Svaren J, Bertics PJ and Darien BJ (2002)
Modulation of monocyte signaling and pore formation in response to agonists of
the nucleotidereceptor P2X(7). Journal of Leukocyte Biology 72 222-232 Agaisse H, Petersen UM, Boutros M, Mathey-Prevot B and Perrimon N (2003) Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Developmental Cell 5 441-450 Agami R (2007) All roads lead to IKKepsilon. Cell 129 1043-1045 Agapova OA, Kaufman PL and Hernandez MR (2006) Androgen receptor and NFkB expression in human normal and glaucomatous optic nerve head astrocytes in vitro and in experimental glaucoma. Experimental Eye Research 82 1053-1059 Agarwal A, Das K, Lerner N, Sathe S, Cicek M, Casey G and Sizemore N (2004) The AKT/IkB kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kB and beta-catenin. Oncogene 24 1021-1031 Agarwal C, Dhanalakshmi S, Singh RP and Agarwal R (2003) Inositol
hexaphosphate inhibits constitutive activation of NF-kB in
androgen-independent human prostate carcinoma DU145 cells. Anticancer Research
23 3855-3861 Aggarwal AK (1995) A gripping end to NF-kB. Nature Structural Biology 2
184-186 Aggarwal BB (2007) Nuclear factor-kB: a transcription factor for all seasons. Expert Opinion on Therapeutic Targets 11 109-110 Aggarwal
BB, Bhardwaj A, Aggarwal RS, Seeram NP, Shishodia S and Takada Y (2004) Role
of resveratrol in prevention and therapy of cancer: preclinical and clinical
studies. Anticancer Research 24 2783-2840 Aggarwal BB and Higuchi M (1997) Role of ceramide in tumour necrosis factor-mediated apoptosis and nuclear factor-kB activation. Biochemical Society Transactions 25 1166-1171 Aggarwal BB and Ichikawa H (2005) Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. Cell Cycle 4 1201-1215
Aggarwal BB, Ichikawa H, Garodia P, Weerasinghe P, Sethi G, Bhatt ED, Pandey
MK, Shishodia S and Nair MG (2006) From traditional Ayurvedic medicine to
modern medicine: identification of therapeutic targets for suppression of
inflammation and cancer. Aggarwal BB, Kunnumakkara AB, Harikumar KB, Tharakan ST, Sung B and Anand P (2008) Potential of spice-derived phytochemicals for cancer prevention. Planta Medica in press Aggarwal BB and Shishodia S (2004) Suppression of the nuclear factor-kB activation pathway by spice-derived phytochemicals: reasoning for seasoning. Annals of the New York Academy of Sciences 1030 434-441 Aggarwal BB and Shishodia S (2006) Molecular targets of dietary agents for prevention and therapy of cancer. Biochemical Pharmacology 71 1397-1421 Aggarwal
BB, Shishodia S, Ashikawa K and Bharti AC (2002) The role of TNF and
its family members in inflammation and cancer: lessons from gene deletion.
Current Drug Targets of Inflammation and Allergy 1 327-341 Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE and
Price JE (2005) Curcumin suppresses the paclitaxel-induced nuclear factor-kB
pathway in breast cancer cells and inhibits lung metastasis of human breast
cancer in nude mice. Clinical Cancer Research 11 7490-7498 Aggarwal BB, Takada Y and Oommen OV (2004) From chemoprevention to
chemotherapy: common targets and common goals. Expert Opinion on Investigational Drugs 13
1327-1338 Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S and Aggarwal BB (2006) Curcumin (diferuloylmethane) downregulates expression of cell proliferation, antiapoptotic and metastatic gene products through suppression of IkBa kinase and AKT activation. Molecular Pharmacology 69 195-201 Aggarwal S, Takada Y, Mhashilkar AM, Sieger K, Chada S and
Aggarwal BB (2004) Melanoma differentiation-associated gene-7/IL-24 gene
enhances NF-kB activation and suppresses apoptosis induced by TNF. Journal of
Immunology 173 4368-4376 Aghai ZH, Kode A, Saslow JG, Nakhala T, Farhath S, Stahl GE, Eydelman R, Strande L, Leone P and Rahman I (2007) Azithromycin suppresses activation of nuclear factor-kB and synthesis of pro-inflammatory cytokines in tracheal aspirate cells From premature infants. Pediatric Research in press Aghai ZH, Kumar S, Farhath S, Kumar MA, Saslow J, Nakhla T, Eydelman R, Strande L, Stahl G, Hewitt C, Nesin M and Rahman I (2005) Dexamethasone suppresses expression of nuclear factor-kB in the cells of tracheobronchial lavage fluid in premature neonates with respiratory distress. Pediatrics Research 59 811-815 Aghajanian C (2004) Clinical update: novel targets in gynecologic malignancies. Seminars in Oncology 31 22-26
Agou F, Courtois G, Chiaravalli J, Baleux F, Coic YM, Traincard F, Israel A
and Veron M (2004) Inhibition of NF-kB activation by peptides targeting NEMO
oligomerisation. Journal of Biological Chemistry 279 54248-54257 Agou F, Courtois G, Chiaravalli J, Baleux F, Coic YM, Traincard F, Israel A and Veron M (2004) Inhibition of NF-kB activation by peptides targeting NF-kB essential modulator (nemo) oligomerization. Journal of Biological Chemistry 279 54248-54257
Agou F, Traincard F, Vinolo E, Courtois G, Yamaoka S, Israel A and Veron M
(2004) The trimerization domain of NEMO is comprised of the interacting
C-terminal CC2 and LZ coiled-coil subdomains. Journal of Biological Chemistry
279 27861-27869
Agrawal
A, Cha-Molstad H, Samols D and Kushner I (2001) Transactivation of C-reactive
protein by IL-6 requires synergistic interaction of CCAAT/enhancer binding
protein beta (C/EBP beta) and Rel p50. Journal of Immunology 166 2378-2384
Agarwal R, Campbell RC and Warnock DG (2004) Oxidative stress in hypertension
and chronic kidney disease: Role of angiotensin II. Seminars in Nephrology 24
101-114
Aguilera C, Fernandez-Majada V, Ingles-Esteve J, Rodilla V, Bigas A and Espinosa L (2006) Efficient nuclear export of p65-IkBa complexes requires 14-3-3 proteins. Journal of Cell Science 119 3695-3704
Aguilera C, Hoya-Arias R, Haegeman G, Espinosa L and Bigas A (2004)
Recruitment of IkBa to the hes1 promoter is associated with transcriptional
repression. Proceedings of the National Academy of Sciences USA 101 16537-16542 Agusti A, Morla M, Sauleda J, Saus C and Busquets X (2004) NF-kB activation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight. Thorax 59 483-487
Ahmad M, Marui N,
Alexander RW and Medford RM (1995) Cell type-specific transactivation of the
VCAM-1 promoter through an NF-kB enhancer motif. Journal of Biological
Chemistry 270 8976-8983
Ahmad R, Riana D, Meyer C, Kharbanda S and Kufe D (2006) Triterpenoid CDDO-Me blocks the NF-kB pathway by direct inhibition of IKKb on Cys-179. Journal of Biological Chemistry 281 35764-35769
Ahmad R, Raina D, Trivedi V, Ren J, Rajabi H, Kharbanda S and Kufe D (2007) MUC1 oncoprotein activates the IkB kinase beta complex and constitutive NF-kB signalling. Nature Cell Biology in press Ahmad SR, Lidington EA, Ohta R, Okada N, Robson MG, Davies KA, Leitges M,
Harris CL, Haskard DO and Mason JC (2003) Decay-accelerating factor induction
by tumour necrosis factor-alpha, through a phosphatidylinositol-3 kinase and
protein kinase C-dependent pathway, protects murine vascular endothelial cells
against complement deposition. Immunology 110 258-268
Ahmed KM, Cao N and Li JJ (2006) HER-2 and NF-kB as the targets for therapy-resistant breast cancer. Anticancer Research 26 4235-4243
Ahmed KM, Dong S, Fan M and Li JJ (2006) Nuclear Factor-kB p65 inhibits mitogen-activated protein kinase signaling pathway in radioresistant breast cancer cells. Molecular Cancer Research 4 945-955 Ahmed KM and Li JJ (2007) ATM-NF-kB connection as a target for tumor radiosensitization. Current Cancer Drug Targets 7 335-342
Ahmed KM and Li JJ (2008) NF-kB-mediated adaptive resistance to ionizing radiation. Free Radical Biology and Medicine 44 1-13
Ahmed MM (2004) Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors. Current Cancer Drug Targets 4 43-52
Ahmed S, Pakozdi A and Koch AE (2006) Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts. Arthritis and Rheumatism 54 2393-2401
Ahmed S, Wang N, Hafeez BB, Cheruvu VK and Haqqi TM (2005)
Punica granatum L. extract inhibits IL-1beta-induced expression of matrix
metalloproteinases by inhibiting the activation of MAP kinases and NF-kB in
human chondrocytes in vitro. Journal
of Nutrition 135 2096-2102
Ahn E, Lee H and Yun Y (2006) LIME acts as a transmembrane
adapter mediating BCR-dependent B cell activation. Blood 107 1521-1527
Ahn J, Feldman G, Terry L, Shore EM and Kaplan FS (2003) Exoneration of NF-kB
dysregulation in fibrodysplasia ossificans progressiva. Clinical Orthopedics
406 205-213
Ahn JY, Choi IS, Shim JY, Yun EK, Yun YS, Jeong G and Song JY (2005) The immunomodulator ginsan induces resistance to experimental sepsis by inhibiting Toll-like receptor-mediated inflammatory signals. European Journal of Immunology 36 37-45 Ahn KS and Aggarwal BB (2005) Transcription factor NF-kB: a sensor for smoke and stress signals. Annals of the New York Academy of Sciences 1056 218-233
Ahe KS, Gong x, Sethi G, Chaturvedi MM, Jaiswal AK and Aggarwal BB (2007) Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases. Cancer Research 67 10004-10011 Ahn KS, Hahn BS, Kwack K, Lee EB and Kim YS (2006) Platycodin D-induced apoptosis through nuclear factor-kB activation in immortalized keratinocytes. European Journal Pharmacology 537 1-11
Ahn KS, Moon KY, Lee J and Kim YS (2003) Downregulation of NF-kB activation in
human keratinocytes by melanogenic inhibitors. Journal of Dermatological Science 31
193-201
Ahn
KS, Noh EJ, Zhao HL, Jung SH, Kang SS and Kim YS (2005) Inhibition of
inducible nitric oxide synthase and cyclooxygenase II by Platycodon
grandiflorum saponins via suppression of nuclear factor-kB activation in RAW
264.7 cells. Life Sciences 76 2315-2328
Ahn KS, Sethi G and Aggarwal BB (2007) Simvastatin potentiates TNF-alpha-induced apoptosis through the down-regulation of NF-kB-dependent antiapoptotic gene products: role of IkBa kinase and TGF-beta-activated kinase-1. Journal of Immunology 178 2507-2516 Ahn KS, Sethi G and Aggarwal BB (2007) Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kB pathway. Biochemical Pharmacology in press Ahn KS, Sethi G and Aggarwal BB (2007) Nuclear factor-kB: from clone to clinic. Current Molecular Medicine 7 619-637
Ahn KS, Sethi G, Chaturvedi MM, Palladino MA, Younes A and Aggarwal BB (2007) Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through downmodulation of NF-kB-regulated gene products. Blood 110 2286-2295 Ahn KS, Sethi G, Jain Ak, Jaiswal AK and Aggarwal BB (2006) Genetic deletion of NAD(PPH:quinone oxidoreductase 1 abrogates activation of nuclear factor-kB, IkBa kinase c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and protentiates apoptosis. Journal of Biological Chemistry 281 19798-19808
Ahn KS, Sethi G, Krishnan K and Aggarwal BB (2007) gamma -tocotrienol inhibits nuclear factor-kB signaling pathway through inhibition of RIP and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. Journal of Biological Chemistry 282 809-820 Ahn KS, Sethi G, Shishodia S, Sung B, Arbiser JL and Aggarwal BB (2006) Honokiol potentiates apoptosis, suppresses Osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kB activation pathway. Molecular Cancer Research 4 621-633 Ahn KY, Kim BH, Lee YR, Hwang DH, Chung EY, Min K and Kim Y (2005) Dual
inhibitory effects of furonaphthoquinone compound on enzyme activity and
lipopolysaccharide-induced expression of cyclooxygenase-2 in macrophages.
Biochemical and Biophysical Research Communications 336 93-99 Ahn
SC, Kim GY, Kim JH, Baik SW, Han MK, Lee HJ, Moon DO, Lee CM, Kang JH, Kim BH,
Oh YH and Park YM (2004) Epigallocatechin-3-gallate, constituent of green tea,
suppresses the LPS-induced phenotypic and functional maturation of murine
dendritic cells through inhibition of mitogen-activated protein kinases and
NF-kB. Biochemical and Biophysical Research Communications 313 148-155 Ahn SK, Choe TB and Kwon TJ (2003) The gene expression profile of human umbilical vein endothelial cells stimulated with lipopolysaccharide using cDNA microarray analysis. International Journal of Molecular Medicine 12 231-236
Ahn SY, Cho CH, Park KG, Lee HJ, Lee S, Park SK, Lee IK and Koh GY (2004) Tumor necrosis factor-alpha induces fractalkine expression preferentially in arterial endothelial cells and mithramycin A suppresses TNF-alpha-induced fractalkine expression. American Journal of Pathology 164 1663-1672
Ahtoniemi T, Goldsteins G, Keksa-Goldsteine V, Malm T, Kanninen K, Salminen A and Koistinaho J (2007) Pyrrolidine dithiocarbamate inhibits induction of immunoproteasome and decreases survival in a rat model of amyotrophic lateral sclerosis. Molecular Pharmacology 71 30-37
Ahuja J, Lepoutre V, Wigdahl B, Khan ZK and Jain P (2007) Induction of pro-inflammatory cytokines by human T-cell leukemia virus type-1 Tax protein as determined by multiplexed cytokine protein array analyses of human dendritic cells. Biomedicine & Pharmacotherapy 61 201-208 Aiamkitsumrit B, Zhang X, Block TM, Norton P, Fraser NW and Su YH (2007) Herpes simplex virus type 1 ICP4 deletion mutant virus d120 infection failed to induce apoptosis in nerve growth factor-differentiated PC12 cells. Journal of Neurovirology 13 305-314 Aifantis
I, Gounari F, Scorrano L, Borowski C, von Boehmer H (2001) Constitutive pre-TCR
signaling promotes differentiation through Ca2+ mobilization and activation of
NF-kB and NFAT. Nature Immunology 2 403-409
Aikawa Y, Yamamoto M, Yamamoto T, Morimoto K, Tanaka K (2002) An
anti-rheumatic agent T-614 inhibits NF-kB activation in LPS- and TNF-alpha-stimulated
THP-1 cells without interfering with IkBa degradation. Inflammation Research
51 188-194 Ainbinder E, Amir-Zilberstein L, Yamaguchi Y, Handa H and Dikstein R (2004)
Elongation inhibition by DRB sensitivity-inducing factor is regulated by the
A20 promoter via a novel negative element and NF-kB. Molecular and Cellular
Biology 24 2444-2454 Ait-Ghezala G, Mathura VS, Laporte V, Quadros A, Paris D, Patel N, VOlmar CH,
Kolippakkam D, Crawford F and Mullan M (2005) Genomic regulation after CD40
stimulation in microglia: Relevance to Alzheimer's disease. Brain Research
Molecular Brain Research 140 73-85
Ait-Said F, Elalamy I, Werts C, Gomard MT, Jacquemin C, Couetil JP and Hatmi M
(2003) Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2
expression in human microvascular endothelial cells: involvement of
lipoxygenase-derived metabolites and p38 MAPK pathway. Biochimica et
Biophysica Acta 1631 77-84 |