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Sean J. Elliott
Department of Chemistry,
Boston University
590 Commonwealth Avenue
Boston, MA 02215
U.S.A.
elliott@bu.edu
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Welcome. Starting in 2002, I have made myself a happy home in
Boston, at the Department of Chemistry
at Boston University, as an Assistant
Professor. My research group has taken root, and in the classroom I have
taught classes ranging from Freshman Chemistry to Physical Methods in
Inorganic Chemistry.
Before my time in Boston, I was living for a few years in
Oxford, England, where I was an EMBO-funded post-doctoral scholar in the laboratory of
Prof.
Fraser A. Armstrong, studying protein film voltammetry within the
Inorganic
Chemistry Laboratory, of the
University of Oxford.
Welcome to my world.
Scientifically, I am interested in biological redox chemistry, metalloprotein
structure and function, and the ways in
which biological systems interact with metal ions -- whether metal reduction
for bacterial anaerobic respiration, or metal recognition and uptake.
In my research group, we use a wide-range of biochemical
and analytical tools, to investigate redox-active proteins, enzymes, and
biochemical pathways. Our repertoire of interests features the
electrochemical technique of protein film voltammetry (PFV).
PFV is a unique tool, and during my post-doc I used it to study many
different proteins and enzymes which transfer electrons in biological systems.
Via this technique, one is able to examine the ET reactions involved,
as well as winkle out new insights into how enzymes work as machines. Below
(eventually) you will see some links to some of the projects my lab is currently
exploring: cytrochrome c peroxidase from Nitrosomonas europaea,
thioredoxin and thioredoxin reductases, as well as copper proteins of the
Cu-efflux pathways of E. coli -- just to name a few.
I received my Ph.D. from the Division of Chemistry and Chemical Engineering at
Caltech in 2000, under the
supervision of Prof. Sunney I. Chan, studying the particulate methane
monooxygenase from Methylococcus capsulatus (Bath). Caltech is a
wonderful place, and through my time there, I was able to work on techniques
as far ranging as gene cloning and sequencing, to membrane protein
purification, to XAS and EPR spectroscopies.
Prior to my time in sunny Los Angeles, I was Chemistry and English major
at Amherst College, in lovely
Amherst, Massachusetts, where I read many books, wrote what I thought about
them, played volleyball, and studied Chemistry under the
supervision of Prof. Joan Broderick, now at Montana State University in
Bozeman, MT.
I grew up amongst the sun and cactus and mountains of Tucson, Arizona. Go Cats.
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