Professor Morgan's research focuses on the interactions between mechanical forces and tissue microstructure in the maintenance, regeneration, and degradation of skeletal tissues. These tissues, which include bone, cartilage, ligament, and tendon, have hierarchical microstructures that span multiple length scales. At nearly every scale, skeletal tissues change dramatically in structure in response to mechanical loading. In some cases, these changes are beneficial, as they lead to a stronger, more “biomechanically competent” skeleton. However, in other situations, these changes involve progressive destruction of the tissues, leading to conditions such as osteoarthritis and bone fractures. Understanding how mechanical forces can cause such a wide spectrum of responses will aid in injury treatment/prevention and tissue engineering.