Soo Lee's Page
	Full name : Soohyun Lee e-mail : duplexa (at) bu.edu Ph.D. in Bioinformatics, Boston University
Hi, my name is Soohyun Lee. I studied under prof. Zhiping Weng, prof. Simon Kasif and prof. Charles Cantor while I was a graduate student at Boston University. Prof. Weng has moved since 2008 to Univ. Massachusetts Medical School (UMMS) as a director of Bioinformatics and Integrative Biology Program, where I began working as a postdoc in Jan 2009. Main Research Interests : Currently, I participate in development of computational pipeline and perform various statistical analyses for small RNA deep sequencing data in D.melanogaster (fruit fly), in collaboration with Prof.Phil Zamore and Prof.Bill Theurkauf. I also work with Prof. Nick Rhind on identification and analysis of Yeast replication origins, based on true single molecule sequencing (Helicos). Education : Jan 2009, Ph.D. in bioinformatics, Boston University. Feb 2002, B.S. in biological sciences w/ minor in applied mathematics, Korea Advanced Institute of Science & Technology (KAIST), Korea Paper Publication : 07. Carla Klattenhoff, Hualin Xi, Chengjian Li, Soohyun Lee, Jia Xu, Jaspreet S. Khurana, Nadine Schultz, Birgit S. Koppetsch, Anetta Nowosielska, Herve Seitz, Phillip D. Zamore, Zhiping Weng, William E. Theurkauf, "The Drosophila HP1 homologue Rhino is required for transposon silencing and piRNA production by dual strand clusters", Cell 2009 (in press) 06. Chengjian Li, Vasily V. Vagin, Soohyun Lee, Jia Xu, Shengmei Ma, Hualin Xi, Hervé Seitz, Michael D. Horwich, Monika Syrzycka, Barry M. Honda, Ellen L.W. Kittler, Maria L. Zapp, Carla Klattenhoff, Nadine Schulz, William E. Theurkauf, Zhiping Weng, Phillip D. Zamore, "Collapse of Germline piRNAs in the Absence of Argonaute3 Reveals Somatic piRNAs in Flies," Cell May 2009. 137(3):509-21 cited 1 times 05. Soohyun Lee, Simon Kasif, Zhiping Weng, Charles R Cantor, "Quantitative Analysis of Single Nucleotide Polymorphisms within Copy Number Variation," PLoS ONE 2008. 3(12): e3906. cited 1 times 04. Megha Ghildiyal, Hervé Seitz, Michael D. Horwich, Chengjian Li, Tingting Du, Soohyun Lee, Jia Xu, Ellen L.W. Kittler, Maria L. Zapp, Zhiping Weng, Phillip D. Zamore, "Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells", Science 2008. v320.pp1077-1081. cited 49 times 03. Soohyun Lee & Simon Kasif, "The complete genome sequence of a dog: a perspective", BioEssays 2006. v.28. p569-573. cited 1 times 02. Soohyun Lee, Isaac Kohane & Simon Kasif, "Genes involved in complex adaptive processes tend to have highly conserved upstream regions", BMC Genomics 2005. 6:168. cited 14 times 01. Soohyun Lee & Changwon Kang, "CHOISS for selection of single nucleotide polymorphism markers on interval regularity", Bioinformatics 2004 March 1; 20(4):581-582 cited 5 times
Other Research Interests : I have previous research experience on the following subjects: Simulation of evolution, codon volatility, chronic myeloid leukemia, chromosomal instability, miRNA target prediction, RNA secondary structure, RNA degradation via ARE, stomach cancer susceptibility, population association studies, RNA editing in human, CTCF, ChIP-chip and ChIP-seq data analysis, mammalian 3'UTR, Support vector machine, suffix tree, Naive Bayes, Markov process.
Teaching Experience : I have tought the following lectures : * Markov model (BF561, DNA and protein sequence analysis, 2004, TA) * Hidden Markov model (BF561, DNA and protein sequence analysis, 2004, TA) * Unix and Perl (3 labs, BF561, DNA and protein sequence analysis, 2004, TA) * Pairwise sequence alignment (BF561, DNA and protein sequence analysis, 2007, guest lecturer) * "Introduction to biostatistics for genomic-scale technologies" (Cold Spring Harbor Laboratory 2007 Systems Biology Workshop)
Hobbies : From time to time I make computer games for fun. When I have more time, I like to learn about sharks and to travel aquariums. Making and listening to music and practicing ballet help me stay happy and healthy.
Created : 9 May 2004 Last modified : 17 Aug 2009 visits since last modified