Cassandra L. Smith – Publications

    1. Smith, C. L. 1971. The Effect of Aflatoxin on the Phagocytosis of Histoplasma capsulatum. M. S. Thesis, West Virginia University.

    2. Smith, C. L. 1976. DNA Polymerase II from and Escherichia coli MutT1 strain. Ph.D. Thesis, Texas A and M University.

    3. Smith, C. L., H. Shizuya and R. E. Moses. 1976. Deoxyribonucleic acid polymerase II Activity in an Escherichia coli mutator strain. J. Bacteriol., 125:191-196.

    4. Smith, C L. and M. Oishi. 1976. The Molecular Mechanism of Virus Induction I. A Procedure for the Biochemical Assay of Prophage Induction. Mol. Gen. Genet., 148:131-138.

    5. Smith, C. L. and M. Oishi. 1978. The Early Events and Mechanisms in the Induction of SOS Functions: Analysis of the Phage Repressor Inactivation Process in vivo. Proc. Natl. Acad. Sci., 75:1657-1661.

    6. Oishi, M. and C. L. Smith. 1978. Inactivation of Phage Repressor in a Permeable Cell System: Role of the recBC-DNase in Induction and Recombination. Proc. Natl. Acad. Sci., 75:3569-3573.

    7. Smith, C. L., M. Kubo and F. Imamoto. 1978. Promoter-Specific Inhibition of Transcription by Antibiotics which Act on DNA gyrase. Nature, 275:420-423.

    8. Oishi, M., C. L. Smith and B. Friefeld. 1979. Molecular Events and Molecules that Lead to Induction of phage and SOS Functions. Cold Spring Harbor Symp. Quant. Biol., 43:897-908.

    9. Smith, C. L. 1983. recF-Dependent Induction of recA Synthesis by Coumermycin, a Specific Inhibitor of the B Subunit of DNA gyrase. Proc. Natl. Acad. Sci., 80:2510-2513.

    10. Smith, C. L., E. Siegfried and P. Ruvola. 1983. Adaptive Doses of MNNG Efficiently Induce a recA-trp gene Fusion. DNA, 2:291-296.

    11. Cantor, C. R., R. Benezra, C-F Hui, C.L. Smith and J. Welsh. 1984. Mapping the Structure of Macromolecular Assemblies by Combining Chemical Modification and Separation Methods. Proc. Int. Symp. Biolmol. Struct. Interactions, Suppl. J. Biosci., 8:739-745.

    12. Smith, C. L. 1985. Response of recA Dependent Operons to Different DNA Damage Signals. J. Biol. Chem., 260:10069-10074.

    13. Smith, C. L. and C.R. Cantor. 1986. Pulsed-Field Gel Electrophoresis of Large DNA Molecules. Nature, 319:701.

    14. Smith, C. L., P. Warburton, A. Gaal and C. R. Cantor. 1986. Analysis of Genome Organization and Rearrangements by Pulsed Field Gradient Gel Electrophoresis. In, Genetic Engineering, (eds.) J. K. Setlow and A. Hollaender, Plenum, NY, 8:45-70.

    15. Cantor, C. R., C-F Hui, C. Kang, C. L. Smith and P. Wollenzien. 1986. RNA Structure in Solution and on the 30 S Ribosomal Subunit. In, Structure, Function, and Genetics of Ribosomes, Springer-Verlag series in Molecular Biology, (eds.) B. Hardesty and G. Kramer, pp. 203-216.

    16. Lawrance, S. K., R. Srivastava, M. J. Chorney, B. Rigas, H. Vasavada, G. A. Gillespie, C. L. Smith, C. R. Cantor, F. S. Collins and S. M. Weissman. 1986. Molecular Approaches to Characterization of Megabase Regions of DNA: Studies of the Human Histocompatibility Complex. Cold Spring Harbor Symp. Quant. Biol., 51:123-130.

    17. Smith, C. L. and C. R. Cantor. 1986. Macrorestriction Mapping by Pulsed Field Gel Electrophoresis. In, Applications of DNA Probes, Banbury Report, Cold Spring Harbor Press, NY, pp. 87-92.

    18. Cantor, C. R., P. Warburton, C. L. Smith and A. Gaal. 1986. Voltage Ramp Pulsed Field Gel Electrophoresis Separation of Large DNA Molecules. In, Electrophoresis ‘86, (ed.) M. Dunn, VCH Publishers, Weinheim, pp. 161-171.

    19. Srivastava, R., S. K. Lawrance, C. L. Smith, C. R. Cantor and S. M. Weissman. 1986. Long Range and Molecular Mapping of the Human Major Histocompatibility Complex. Transactions of American Association of Physicians, 49:1-12.

    20. Lawrance, S. K., C. L. Smith, S. M. Weissman and C. R. Cantor. 1987. Megabase-Scale Mapping of the HLA Gene Complex by PFG electrophoresis. Science, 235:1387-1390.

    21. Smith, C. L., S. K. Lawrance, G. A. Gillespie, C. R. Cantor, S. M. Weissman and F. S. Collins. 1987. Strategies for Mapping and Cloning Macro-Regions of Mammalian Genomes. In, Methods in Enzymology, Molecular Genetics of Mammalian Cells, ed. M. Gottesman, Academic Press, New York, 151:461-489.

    22. Smith, C. L. and C. R. Cantor. 1987. Purification, Specific Fragmentation, and Separation of Large DNA Molecules. In, Methods in Enzymology, “Recombinant DNA”, (ed.) R. Wu, Academic Press, New York, 155: 449-467.

    23. Smith, C. L. and C. R. Cantor. 1987. Approaches to Physical Mapping of the Human Genome. Cold Spring Harbor Symp. Quant. Biol., 51:115-122.

    24. Cantor, C. R., C. L. Smith and C. Argarana. 1987. Strategies for Finishing Physical Maps of Macro-DNA Regions. In, Symposium on Integration and Control of Metabolic Processes: Pure and Applied Aspects. ICSU Press, Cambridge, England, pp. 427-438.

    25. Smith, C. L., T. Matsumoto, O. Niwa, S. Klco, J. B. Fan, M. Yanagida and C.R. Cantor. 1987. An Electrophoretic Karyotype for Schizosaccharomyces pombe by Pulsed Field Gel Electrophoresis. Nucl. Acids Res., 15:4481-4490.

    26. Smith, C. L., J. Econome, A. Schutt, S. Klco and C. R. Cantor. 1987. A Physical Map of the E. coli K12 Genome. Science, 236: 1448-1453.

    27. Srivastava, R., M. J. Chorney, S. K. Lawrance, J. Pan, Z. Smith, C. L. Smith and S. M. Weissman. 1987. Structure, Expression and Molecular Mapping of a Divergent Member of the Class I HLA Gene Family. Proc. Natl. Acad. Sci., 84:4224-4228.

    28. Smith, C. L. and C. R. Cantor. 1987. Preparation and Manipulation of Large DNA Molecules: Advances and Applications. TIBS, 12:284-287.

    29. Wellems, T., D. Walliker, C. L. Smith, V. Rosario, W. Maloy, R. Howard, R. Carter and T. McCutchen. 1987. Histidine-Rich Protein Genes Mark Selected Linkage Group in a Genetic Cross of Plasmodium faciparum. Cell, 49:633-642.

    30. Smith, C. L., P. Warburton and C. R. Cantor. 1987. Applications of Pulsed Field Gradient Gel Electrophoresis to Gene Mapping in Simple Organisms. J. of Indian Acad. Sci., In press.

    31. Smith, C. L., M.T. Yu, and C. R. Cantor. 1987. Phased Approaches to Mapping the Physical Structure of Entire Chromosomes. In, Architecture of Eukaryotic Genes, (ed.) G. Kahl, VCH Publisher, Weinheim, pp. 489-496.

    32. Cantor, C. R., C. L. Smith and M. K. Mathew. 1988. Pulsed Field Gel Electorphoresis of Very Large DNA Molecules. Annual Review of Biophysics and Biophysical Chemistry, 17:287-304.

    33. Cantor, C. R., S. Bondopadhyay, S. K. Bramachari, C.-F. Hui, M. McClelland, R. Morse and C. L. Smith. 1988. Torsional Stress, Unusual DNA Structures, and Eukaryotic Gene Expression. In, Unusual DNA Structures, (eds.) R.D. Wells, S.C. Harvey. Springer-Verlag, New York, pp. 73-89.

    34. Berman, J. E., S. J. Mellis, R. Pollack, C. L. Smith, H. Suh, B. Heinke, C. Kowal, U. Surti, L. Chess, C. R. Cantor and F. Alt. 1988. Content and Organization of the Human IG VH Locus: Definition of Three New VH Families and Linkage to the IG CH Locus. Embo. J., 7:727-731.

    35. Smith, C. L. and R. D. Kolodner. 1988. Physical Mapping of E. coli Chromosomal Tn5 and F Insertions by Pulsed Field Gel Electrophoresis. Genetics, 119:227-236.

    36. Petrukhin, K. E., N. E. Broude and C. L. Smith. 1988. A Simple and Efficient Method for Isolating High Molecular Weight DNA From Frozen Mammalian Tissue. Nucleic Acids Res., 16:5696.

    37. Drumm, M. L., C. L. Smith, M. Dean, J. L. Cole, M. C. Lannuzzi and F. S. Collins. 1988. Physical Mapping of the Cystic Fibrosis Region by Pulsed Field Gel Electrophoresis. Genomics 2:346-354.

    38. Sanz, J. L., I. Marin, L. Ramirez, J. P. Abad, C. L. Smith and R. Amils. 1988. Variable rRNA Gene Copies in Extreme Halobacteria. Nucleic Acids Res., 16:7827-7832.

    39. Lee, C. C., C. L. Smith,Y. Kohara, W. J. Cragin and T. Caskey. 1988. Rapid and Precise Mapping of the Escherichia coli Release Factor Genes by Two Physical Mapping Approaches. J. Bact., 170: 4537-4541.

    40. Cantor, C. R. and C. L. Smith. 1988. Mapping the Genome. In, Biotechnology and the Human Genome: Innovations and Impact, (eds.) A.D. Woodhead and B.J. Barnhart, Plenum Press, New York, pp. 11-28.

    41. Smith, C. L., S. R. Klco and Cantor, C. R. 1988. Pulsed Field Gel Electrophoresis and the Technology of Large DNA Molecules. In, Genome Analysis: A Practical Approach, (ed.) K. Davies, IRL Press, Oxford, England, pp. 41-72.

    42. Mathew, M. K., C. L. Smith and C. R. Cantor. 1988. High-Resolution Separation and Accurate Size Determination in Pulsed Field Gel Electrophoresis of DNA. I. DNA Size Standards and the Effect of Agarose and Temperature. Biochemistry, 27:9204-9210.

    43. Mathew, M. K., C. L. Smith and C. R. Cantor. 1988. High-Resolution Separation and Accurate Size Determination in Pulsed Field Gel Electrophoresis of DNA. II. Effect of Pulse Time and Electric Field Strength and Implications for Models of the Separation Process. Biochemistry, 27:9210-9216.

    44. Cantor, C. R., A. Gaal and C. L. Smith. 1988. High-Resolution Separation and Accurate Size Determination in Pulsed Field Gel Electrophoresis of DNA. III. Effect of Electrical Field Shape. Biochemistry, 27:9216-9221.

    45. Mathew, M. K., C-F. Hui, C. L. Smith and C. R. Cantor. 1988. High-Resolution Separation and Accurate Size Determination in Pulsed Field Gel Electrophoresis of DNA. IV. The Influence of DNA Topology. Biochemistry, 27:9222-9226.

    46. Cantor, C. R., L. Pevny and C. L. Smith. 1988. Organization and Evolution of Genomes as Seen from a Megabase Perspective. In, Evolutionary Tinkering in Gene Expression, (eds) M. Grunberg-Manago, B. F. C. Clark and H. G. Zachau, NATO ASI Series, vol. 169. Plenum Press, New York. pp. 143-154.

    47. Aasland, R., J. Coleman, A. L. Holk, C. L. Smith, C. R. H. Raetz and K. Kleppe. 1988. Identity of the 17-Kilodalton Protein, a DNA-Binding Protein from Escherichia coli, and the firA Gene Product. J. Bact., 170:5916-5918.

    48. Aasland, R., and C. L. Smith. 1988. An Efficient Manual Method for Aligning DNA Restriction Map Data on very Large Genomic Restriction Maps. Nucleic Acids Res., 16:10392.

    49. Whaley, W. L., F. Michiels, M. E. MacDonald, D. Romano, M. Zimmer, B. Smith, J. Leavitt, M. Bucan, J. L. Haines, T. C. Gilliam, G. Zehetner, C. L. Smith, C. R. Cantor, A.-M. Frischauf, J. J. Wasmuth, H. Lehrach, and J. F. Gusella. 1988. Mapping of D4S98/S114/S113 Confines the Huntington’s Defect to a Reduced Physical Region at the Telomere of Chromosome 4. Nucleic Acids Res., 16:11769-11780.

    50. Smith, C. L., and C. R. Cantor. 1989. Evolving Strategies for Making Physical Maps of Mammalian Chromosomes. Genome 31:105-1058.

    51. Cantor, C. R. and C. L. Smith. 1989. Large DNA Technology and Possible Applications in Gene Transfer. In, Gene Transfer in Animals: UCLA Symposium on Molecular and Cellular Biology, (eds.) I. Verma, R. Mulligan, A. Beauset. Alan R. Liss, Inc. New York, New Series, Vol. 87, 269-281.

    52. Smith, C. L., and C. R. Cantor. 1989. Construction of Physical Maps and Their Application in Finding Genes. In, Molecular Genetics of Neuromuscular Disease, (eds.) L.P. Rowland, D.S. Wood, E.A. Schon, and S. DiMauro. Oxford Univ. Press, Oxford, England, pp. 172-183.

    53. Smith, C. L., G. Condemine, S.-Y. Chang, E. McGary and S. Chang. 1989. Insertion of Rare Cutting Sites Nearby Genes Allows Their Rapid Physical Mapping: Localization of the E. coli map locus. Nucleic Acids Res., 17:817.

    54. Fan, J.-B., Y. Chikashige, C. L. Smith, O. Niwa, M. Yanagida and C. R. Cantor. 1989. Construction of a Not I Restriction Map of the Fission Yeast Schizosaccharomyces pombe Genome. Nucleic Acids Res., 12:2801-2817.

    55. Van der Ploeg, L. H. T., C. L. Smith, R. I. Polvere and K. M. Gottesdiener. 1989. Improved Separation of Chromosome-sized DNA from Trypanosoma brucei, Stock 427-60. Nucleic Acids Res., 17:3217-3227.

    56. Ohki, M. and C. L. Smith. 1989. Tracking Bacterial DNA Replication Forks in vivo by Pulsed Field Gel Electrophoresis. Nucleic Acids Res., 17:3479-3490.

    57. Cheng, J.-F., C. L. Smith and C. R. Cantor. 1989. Isolation and Characterization of a Human Telomere. Nucleic Acids Res., 17:6109-61287.

    58. Smith, C. L. 1989. New Approaches to Studying Chromosome Structure using Pulsed Field Gel Electrophoresis. In, Frontiers of Chemical Research: Biotechnology, American Chemical Society, Columbus, Ohio, pp. 141-148.

    59. Smith, C. L. and W. M. Michels. 1989. Preliminary Characterization of the Familiar Alzhiemer’s Disease and the Amyloid Gene Regions of Chromosome 21. In: International Symposium on Dementia: Molecular Biology and Genetics of Alzhiemer’s Disease. (eds.) T. Miyatake, Y. Ihara, and D. J. Selkoe. Elsevier Science Publishers B. V. Amsterdam, pp. 197-204.

    60. Doggett, N. A., J. F. Cheng, C. L. Smith and C. R. Cantor. 1989. The Huntington’s Disease Gene is Most Likely Within 325 kb of the Chromosome 4 Telomere. Proc. Natl. Acad. Sci., 86:10011-10014.

    61. Rose, E. A., C. A. Jones, W. H. Lewis, T. Glaser, K. Call, M. Minden, E. Champagne, C. L. Smith, L. Bonetta, and D. E. Houseman. 1989. Complete Physical Map of the WAGR Region of 11p13 Localizes a Candidate Wilm’s Tumor Gene. Cell 60:495-508.

    62. Pevny, L., S. Mita, E. A. Schon, J. Herbert, R. Mayeaux, M. T. Yu and C.L. Smith. 1990. Chromosome 21 Sequences Are Not Duplicated in Alzheimer’s Disease: An Analysis By Pulsed Field Gel Electrophoresis. In, Biotechnology and Human Genetic Predisposition to Disease. UCLA Symposia on Molecular and Cellular Biology. New Series, (eds.) C. R. Cantor, T. Caskey, L. Hood, D. Kamely, and G. Omenn. Alan R. Liss, Inc., N. Y. 126: 21-28.

    63. Cantor, C. R. and C. L. Smith. 1990. Challenges in the Human Genome Project. In, Structure and Function of Nucleic Acids and Proteins, (eds.) F. Y. H. Wu and C. W. Wu, Raven Press Ltd., New York. pp. 115-119.

    64. Smith, C. L. 1990. Recent Developments in the Analysis of Chromosome-Sized DNA and Their Application to Studies of Giardia lamblia and Trypanosoma brucei. In, P&S Biomedical Sciences Symposia: Immune Recognition and Evasion: Molecular Aspects of Host-Parasite Interaction, (eds.) L.H.T. Van der Ploeg, C.R. Cantor, and H.J. Vogel. Academic Press, N.Y., pp. 237-243.

    65. Cantor, C. R. and C. L. Smith. 1990. Perspectives on the Human Genome Project. In, Biotechnology and Human Genetic Predisposition to Disease. UCLA Symposia on Molecular and Cellular Biology. New Series, (eds.) C. R. Cantor, T. Caskey, L. Hood, D. Kamely, and G. Omenn. Alan R. Liss, Inc., N. Y., 126: 1-12.

    66. Cantor, C. R. and C. L. Smith. 1990. Construction and Applications of Physical Maps of the Human Genome. Jikken Igaku (Experimental Medicine). 8:14-22.

    67. Smith, C. L., G. Condemine and S. Ringquist. 1990. Electrophoretic Analysis of Large DNA: Application to the Structure and Dynamics of the E. coli Chromosome. In, The Bacterial Chromosome, (eds.) M. Riley and K. Drlica, American Society for Microbiology, Washington, D. C., pp. 205-210.

    68. Condemine, G. and C. L. Smith. 1990. Genetic Mapping Using Large DNA Technology: Alignment of Sfi I and Avr II Sites with the Not I Genomic Restriction Map of Escherichia coli K12. In, The Bacterial Chromosome, (eds.) M. Riley and K. Drlica, American Society for Microbiology, Washington, D. C., pp. 53-60.

    69. Smith, C. L., J. P. Abad and G. Condemine. 1990. Pulsed Field Gel Electrophoretic Snapshots of Chromosomes. In, Automation and New Technology in the Clinical Laboratory,(ed.) K. Okuda. Blackwell Scientific Publications, Oxford, England., pp. 43-46.

    70. Smith, C. L. and G. Condemine. 1990. New Approaches for Physical Mapping in Small Genomes. J. Bacteriol., 172:1167-1172.

    71. Cantor, C. R. and C. L. Smith. 1990. Impact of the Human Genome Project on the Understanding, Treatment, and Prevention of Cancer. Accomplishments in Cancer Research 1989,( eds.) J.G. Fortner and J.E. Rhoads, J. B. Lippencott Co., Philadelphia, p.267.

    72. Lichens-Park, A., C. L. Smith and M. Syvanen. 1990. Integration of Lambda Bacteriophage into the Cryptic Prophages of Escherichia coli. J. Bacteriol., 172:2201-2208.

    73. Lawrance, S. K. and C. L. Smith. 1990. Megabase Scale Restriction Fragment Polymorphisms in the Human Major Histocompatibility Complex. Genomics, 8:394-399.

    74. Cheng, J. F. and C. L. Smith. 1990. YAC Cloning of Telomeres. Genetic Analysis: Techniques and Applications. 7:119-125.

    75. Beach, D., P. Nurse, W. Ansorge, P. Munz, C. L. Smith, P. Rice, H. Lehrach and M. Yanagida. 1990. A fission yeast genome project. The New Biologist, 2:929.

    76. Condemine, G., and C. L. Smith. 1990. Transcription Regulates Oxolinic Acid Induced DNA gyrase Cleavage at Specific Sites on the E. coli Chromosome. Nucleic Acids Res., 18:7389-7396.

    77. Abad, J. P., C. L. Smith and R. Amils. 1991. Genomic Organization Studies in Halobacteria using Pulsed Field Gel Electrophoresis. In, General and Applied Aspects of Halophilic Microorganims. (ed.) F. Rodrequez-Valera. Plenum Press, N. Y. pp. 295-302.

    78. Cheng, J. F., C. L. Smith and C. R. Cantor. 1991. Structural and Transcriptional Analysis of a Human Subtelomeric Repeat. Nucleic Acids Res., 19:149-154.

    79. Billings, P. R., C. L. Smith and Cantor, C. R. 1991. New Techniques for the Physical Mapping of the Human Genome. FASEB Journal, 5:28-34.

    80. Oliva, R., S. K. Lawrance, Y. Wue and C. L. Smith. 1991. Chromosomes: Molecular Studies. In, Encyclopedia of Human Biology, R. Dulbecco et al., (eds.) Academic Press, San Diego., pp. 475-488.

    81. Smith, C. L. 1991. Separation and Analysis of DNA by Electrophoresis. Current Opinion in Biotechnology, 2:86-91.

    82. Zhang, T. Y., C. L. Smith and C. R. Cantor. 1991. Secondary Pulsed field Gel Electrophoresis. Nucleic Acids Res, 19: 1291-1296.

    83. Fan, J.-B., S. H. Korman, C. R. Cantor and C. L. Smith. 1991. Giardia lamblia: Genome Size Determination by Pulsed Field Gel Electrophoresis is less than 12 Mb. Nucleic Acids Research, 10: 618-630.

    84. Saito, A., J. P. Abad, D. Wang, M. Ohki, C. R. Cantor and C. L. Smith. 1991. Construction and Characterization of a Human Chromsome 21 Not I Linking Library. Genomics, 10:618-630.

    85. Cantor, C. R. and C. L. Smith. 1991. Mapping and Sequencing the Human Genome. In, Molecular Genetic Approaches to Neuropsychiatric Disease. (eds) J. Brosius and R. T. Fremeau. Academic Press, San Diego., pp. 19-34.

    86. Wang, D., Sainz, J., Oliva, R., Wu, Y., Smith, C. L. and Cantor, C. R. 1991. Progress in Making Complete Maps of Human Chromosomes. In, Advances in Gene Technology: The Molecular Biology of Human Genetic Disease. Proceedings of the 1991. Miami Bio/Technology Winter Symposium, (eds) F. Ahmad, H. Bialy et al., Miami Short Reports, Vol. 1, IRL Press., p. 57.

    87. Fan, J. B., D. Grothues and C. L. Smith. 1991. Alignment of Sfi I sites with the S. pombe Not I Restriction Map. Nucleic Acids Res., 19:6289-6294.

    88. Cantor, C. R., and C. L. Smith. 1992. Implications of the Human Genome Project for Clinical Neurosurgery. In, The Molecular and Genetic Basis of Neurological Disease, (eds) R. Rosenberg, S. B Prusiner, S. DiMauro, R. Bachi and L. Kunkel. Butterworth Publishers, Stoneham. Mass., pp. 19-34.

    89. Ichikawa, H., K. Simizu, A. Saito, D. Wang, H. Kobayashi, Y. Kaneko, H. Miyoshi, C. L. Smith, C. R. Cantor and M. Ohki. 1992. Long-distance Restriction Mapping of the Proximal Long Arm of Human Chromosome 21 with Not I Linking Clones. Proc. Nat. Acad. Sci., 89:23-27.

    90. Baehr, A., G. Dunham, A. Ginsburg, R. Hagstrom, D. Joerg, T. Kazic, H. Matsuda, G. Michaels, R. Overbeek, K. Rudd and C. L. Smith, R. Taylor, K. Yoshida and D. Zawada. 1992. An Integrated Database to Support Research on Escherchia coli. Technical Report, Mathematics and Computer Science Division (UC402), Argonne National Laboratory, Argonne, Ill. ANL-1/92. pp. 1-59.

    91. Ito, T., C. L. Smith and C. R. Cantor. 1992. Sequence Specific DNA Purification by Triplex Affinity Capture. Proc. Nat. Acad. Sci., 89:495-498.

    92. Wang, D., H. Fang, C. R. Cantor and C. L. Smith. 1992. A Contiguous Not I Restriction Map of Band q22.3 of Human Chromosome 21. Proc. Nat. Acad. Sci., 89:3222-3226.

    93. Sainz, J., L. Pevny, Y. Wu, C. R. Cantor and C. L. Smith 1992. Distribution of Interspered Repeats (Alu and Kpn) on Not I Restriction Fragments of Human Chromosome 21. Proc. Nat. Acad. Sci., 89:1080-1084.

    94. Ringquist, S. and C. L. Smith. 1992. Characterization and Physical Mapping of in vivo Dam and Dcm Methylase Resistant Sites on the Escherichia coli Chromosome. Proc. Nat. Acad. Sci., 89:4539-4543.

    95. Lechner, M., B. Frey, F. Laue, J. Anton-Botella, C. L. Smith, W. Ankenbauer and G. G. Schmitz. 1992. Swa I, a Unique Restriction Endonuclease from Staphylococcus warneri, which recognizes 5′-ATTTAAAT-3′. Nucleic Acids Res., 20:2293-2296.

    96. Doggett, N. A., C. L. Smith and C. R. Cantor. 1992. The Effect of DNA Concentration on Mobility in Pulsed-Field Gel Electrophoresis. Nucleic Acids Res. 89:859-864.

    97. Fan, J. B., M. Rochet, C. Gaillardin and C. L. Smith. 1992. Detection and Characterization of a Ring Chromosome II in the Fission Yeast Schizosaccharomyces pombe. Nucleic Acid Res., 20: 5943-5945.

    98. Lopez,-Garcia, P., J. P. Abad, C. L. Smith and R. Amils. 1992. Genomic Organization of the Halophilic Archaem Haloferax mediterranei: Physical Map of the Chromosome. Nucleic Acid Res., 20:2459-2464.

    99. Ito, T., C. L. Smith and C. R. Cantor. 1992. Affinity Capture Electrophoresis for Sequence-Specific DNA Purification. Genetic Analysis Techniques and Applications., 9:96-99.

    100. Ito, T., I., C. L. Smith and C. R. Cantor. 1992. Triplex Affinity Capture of a Single Copy Clone from a Yeast Genomic Library. Nucleic Acids Res., 20:3624.

    101. Sano, T., C. L. Smith and C. R. Cantor. 1992. Immuno-PCR: A Very Sensitive Antigen Detection System using an DNA-Antibody Conjugate. Science, 258:120-122.

    102. Bremer, M., F. Gimbel, J. Thorner, and C. L. Smith. 1992. VDE Endonuclease Cleaves the Saccharomyces cerevisiae Genomic DNA at a Single Site: Physical Mapping of the VMA1 Gene. Nucleic Acids Res., 20:5484.

    103. Yoshida, K., C. L Smith, T. Kazic, G. Michaels, R. Taylor, D. Zawada, R. Hagstrom and R. Overbeek. 1992. Toward a Human Genome Encyclopedia. Proc. Intl. Conf. on Fifth Generation Computer Systems (FGCS’92), pp. 105-120.

    104. Smith, C. L. R. Oliva, D. Wang, D. Grothues and S. Lawrance. 1993. Physical Strategies for the Molecular Dissection of Genomes, In, Genome Analysis of Protozoan Parasites, IlRAD, Nairobi, Kenya, pp. 2-16.

    105. Smith, C. L., S. Klco, T. Y. Zhang, H. Fang, R. Oliva, J. B. Fan, M. Bremer and S. Lawrance. 1993. Analysis of Megabase DNA using Pulsed Field Gel Electrophoresis, In, Methods in Molecular Genetics, K. W. Adolph (ed.) Academic Press, San Diego, pp. 155-196.

    106. Marin, I., J. P. Abad, C. L. Smith and R. Amils. 1992. Genomic Organization of the Metal-Mobilizing Bacterium, Thiobacillus cuprinus. submitted

    107. Zhu, Y., C. R. Cantor, and C. L. Smith. 1993. DNA Sequence Analysis of Chromosome 21 Not I linking clones. Genomics, 18:199-205.

    108. Gingrich, J. C., S. Lowry, W. L. Kuo, J. Grey, C. L. Smith and C. R. Cantor. 1993. Cloning and characterization of Eag I YACS from Human Chromosome 21. Genomics 15:228-240.

    109. Grothues, D., C. L. Smith and C. R. Cantor. 1993. PCR Amplification of Megabase DNA with Tagged Random Primers (T-PCR). Nucleic Acids Res., 21:1321-1322.

    110. Sano, T., C. L. Smith and C. R. Cantor. 1993. A Streptavidin Mutant containing a Cysteine Stretch that Facilitates Production of a Variety of Specific Streptavidin Conjugates. Bio/Technology, 11:201-206.

    111. Murray, M. N., H. G. Hansma, M. Bezanilla, T. Sano, D. F. Ogletree. W. Kolbe, C. L. Smith, C. R. Cantor, S. Spengler, P. K. Hansma and M. Salmeron. 1993. Atomic Force Microscopy of Biochemically Tagged DNA. Proc. Nat. Acad. Sci., 90:3811-3814.

    112. Smith, C. L., D. Grothues, T. Ito, T. Sano, D. Wang, Y. W. Zhu and C. R. Cantor 1993. Accelerating the Rate of Genome Mapping and Sequencing: Will computational Biology Keep Up? In, H. A. Lim, J. W. Fickett, C. R. Cantor, and R. J. Robbins. The Second International Conference on Bioinformatics, Supercomputing and Complex Genome Analysis., pp. 3-15.

    113. Ruzicka, V., W. Marz, A. Russ, W. Gross, T. Sano, C. L. Smith and C. R. Cantor. 1993. Immuno-PCR using a Commercially available Avidin. Science, 260:688-689.

    114. Zhang, T. Y., J. B. Fan, S. Ringquist, C. R. Cantor and C. L. Smith. 1993. The 0.7 to 3.3 Megabase Chromosomes from Candida, Kluvermyces, and Pichia Provide Accurate Size Standards for Pulsed Field Gel Electrophoresis. Electrophoresis, 14:290-295.

    115. Crow, T. J., M. Poulter, R. Lofthouse, G. Chen, T. Shah, N. Bass, C. Morganti, A. Vita, C. L. Smith, A. B. Boccio-Smith, G. Shields, and L. E. DeLisi. 1993. Male Siblings with Schizophrenia Share Alleles at the Androgen Receptor above Chance Expectations. Am. J. Med. Genetics (Neuropsychiatric Genetics), 48:159-160.

    116. Cantor, C. R., D. Grothues, T. Sano, N. Broude and C. L. Smith. 1993. Implications of Large Scale DNA Analysis for the Study of Microorganisms. Annals of the Japanese Biotechnology Association., pp. 1-6.

    117. Grothues, D., C. R. Cantor and C. L. Smith 1994. Top-down Construction of an Ordered Schizosaccharomyces pombe Cosmid Library. Proc. Nat. Acad. Sci., 91:4461-4465.

    118. Yoshida, K., C. L. Smith and R. Overbeek. 1994. A Primer on Rapid Prototyping of Genomic Databases in Prolog. In, Biocomputing: Informatics and Genome Projects. D. Smith (ed). Academic Press, San Diego, pp. 233-248.

    119. Wang D., and C. L. Smith. 1994. Large Scale Structure Conservation Along the Entire Long Arm of Human Chromosome 21. Genomics, 20:441-451.

    120. Broude, N., T. Sano, C. L. Smith and C. R. Cantor. 1994. Enhanced DNA Sequencing by Hybridization. Proc. Nat. Acad. Sci., 91:3072-3076.

    121. Cantor, C. R., D. Grothues, N. Broude, T. Sano and C. L. Smith. 1995. The Prospects of Large Scale DNA Diagnostics. In, Proceedings of the Conference: Legal Aspects of the Human Genome Project; FundaciÛn, BBV, Bilbao, Spain, pp. 113-119.

    122. Sano, T., M. W. Pandori, C. L. Smith and C. R. Cantor. 1994. Tighter Subunit Association of Streptavidin upon Biotin Binding. Advances in Biomagnetic Separation, ed. Uhlen, M., Hornes, E., and Olsvik, ÿ., Eaton Publishing, Natick, MA, pp. 21-29.

    123. Anton, J, P. Lopez-Garcia. J. P.Abad, C. L. Smith and R. Amils. 1994. Alignment of Genes and Swa I Restriction Sistes to the BamH I Genomic Map of Haloferax mediterranei. FEMS Microbiologgy Letters, 117:53-60.

    124. Smith, C. L, T. Keith, I. Hansmann, J. Weissenbach, F.A. Asimakopoulos, D. W. Bowden, J. F. Deleuze, E. R. Dutton , K.H. Fasman, T. Green , M. Hadchouel, J. Hazan, S. Hilgartner, D. K. Kingsbury, B. Loder, A. Malafosse, M. Meunier-Rotival, P. L. Pearson, L. D. Siracusa, O. Steinlein, N. White, and C. M. Williamson. 1994. Report of The First International Workshop on Human Chromosome 20 Mapping 1994. Cytogenet. Cell. Genet., 66:77-82.

    125. Smith, C. L. 1994. Review of “Strategies for Physical Mapping” In, Genome Analysis, vol. 4, edited by K. E. Davies and S. M. Tilghman. Quarterly Review of Biology, 69:398.

    126. Smith, C. L., D. Wang and D. Grothues. 1995. Construction of Physical Maps of Chromosomes. In, R. A. Meyers (ed), Molecular Biology and Biotechnology: A Comprehensive Desk Reference. VCH Publishers Inc., New York City, N. Y., pp. 420-423.

    127. Sano, T., C. L. Smith and C. R. Cantor. 1995. Immuno-PCR (Immuno-polymerase chain reaction). In, R. A. Meyers (ed), Molecular Biology and Biotechnology: A Comprehensive Desk Reference. VCH Publishers Inc., New York City, N. Y., pp. 458-460.

    128. Cantor, C. R., T. Sano and C. L. Smith. 1995. Implications of Large Scale DNA Analysis for the Development and Application of Biomarkers. In, Biomarkers and Occupational Health: Progress and Perspectives, M. L. Mendelsohn, J. P. Peeters, M. J. Normandy (eds.) John Henry Press. Washington, D. C., pp. 257-263.

    129. Smith, C. L., L. Kricka and U. Krull. 1995. Development of Sensors for Environmental Microbes. Genetic Analysis (Biomolecular Engineering), 12:33-38.

    130. Sano, T., C. L. Smith, and C. R. Cantor. 1995. Detecting Minute Amounts of Antigen. Chemtech, 25:16-23.

    131. Cantor, C. R., N. Broude, T. Sano, M. Przetakiewicz and C. L. Smith. 1996. The Future of DNA Sequencing: Methods and Applications. In, A. L. Burlingame and S. A. Carr (eds), Mass Spectrometry in the Biological Sciences. Humana, Totowa, NJ., pp. 519-533.

    132. Sano, T., C. L. Smith and C. R. Cantor. 1995. Very Sensitive Antigen Detection by Immuno-PCR. Immunoanalysis of Agrochemical: Emerging Technologies, ACS, Washington, D. C. pp. 175-185.

    133. Wang, D., Y. Zhu, and C. L. Smith. 1995. A Set of Inter-Alu PCR Markers for Chromosome 21 Generated from Pulsed Field Gel Fractionated Not I Restriction Fragments. Genomics, 26:318-344.

    134. Fan, J. B., C. R. Cantor and C. L. Smith. 1995. Frequent Rearrangements Near the Ends of Schizosaccharomycs pombe Chromosome III. InterJournal (http://www.dynamics.bu.edu)

    135. Hnatowich, D. J., P. Winnard Jr., F. Virzi, M. Fogarasi, T. Sano, C. L. Smith, C. R. Cantor and M. Rusckowski. 1995. Technetium-99m Labeling of DNA Oligonucleotides. J. Nuclear Medicine, 36: 2306-2314.

    136. Virzi, F., Winnard, V. F. Jr., M. Fogarasi, T. Sano, C. L. Smith, C. R. Cantor, M. Rusckowski and D. J. Hnatowich. 1994. Recombinant Metallothionein-Streptavidin Labeled with 188 Re and 99mTc. 1995. Bioconjugate Chem., 6:139-144.

    137. Niemeyer, C. M.,T. Sano, C. L. Smith and C. R. Cantor. 1994. Oligonucleotide-Directed Self-assembly of Proteins: Semisynthetic DNA-Streptavidin Hybrid Moleucles as Connectors for the Generation of Macroscopic Arrays and the Construction of Supramolecular Bioconjugates. Nucleic Acids Res., 25:5530-5539.

    138. Fu, D. J., N. E. Broude, H. Koster, C. L. Smith and C. R. Cantor. 1995. Efficient Preparation of Short DNA Sequence Ladders Potentially Suitable for MALDI-TOF Sequencing. Genetic Analysis (Biomolecular Engineering), 12:137-142.

    139. Fu, D. J., N. E. Broude, H. Koster, C. L. Smith and C. R. Cantor. 1995. A DNA Sequencing Strategy which Requires only Five Bases of Known Terminal Sequence for Priming. Proc. Nat. Acad. Sci. USA 92:10162-10166.

    140. Smith, C. L, D. Wang, N. Broude, N. Bukanov, G. Monastryskaya and E. Sverdlov. 1996. Parallel Processing in Genome Mapping and Sequencing. In, Methods: A Companion to Methods in Enzymology, M. Schwab (ed.), 9:136-144.

    141. Hnatowich, D. J., G. Mardirossian, M. Fogarasi, T. Sano, C. L. Smith, C. R. Cantor, M. Ruschkowski and P. Winnard, Jr. 1996. Comparative Properties of Technetium-99M-Labeled Single Stranded Natural DNA and a Phosphorothioate Derivative in vitro and in Mice. J. Pharmacology and Exper. Therapeutics, 276:326-334.

    142. Anton, J., R. Amils, C. L. Smith and P. Lopez-Garcia. 1995. Comparative Restriction Maps of the Archeal Megaplasmid PHM300 in Different Haloferz mediterranei strains. System. Appl. Microbiology, 18:439-447.

    143. Cantor, C. R., Sano, T., N. Broude and C. L. Smith. 1995. Parallel Processing in DNA Analysis. In, A. Ferreira and J. Rolim (eds), International Workshop on Parallel Algorithms for Irregularly Structured Problems (2nd: Lyon, France), Lecture Notes in Computer Science 980, Springer Verlag., pp. 171-185.

    144. Fan, J. B. and C. L. Smith. 1995. Structure of Schizosaccharomyces pombe Chromosomes: Mapping and Sequencing Endonuclease Hypersenstive Sites. Genetic Analysis (Biomolecular Engineering), 12:85-93.

    145. Sano, T., G. O. Reznik, P. Szafranski, A. Rai, C. M. Niemeyer, S. Vajda, C. L. Smith, C. M. Mello, D. L. Kaplan, M. Rusckowski, D. J. Hnatowich and C. R. Cantor. 1995. Applications of Streptavidin and Its Genetically Engineered Variants. (Proceedings of International Conference on Molecular Structural Biology, Vienna, submitted.

    146. Sano, T., M. W. Pandori, X. Chen, C. L. Smith and C. R. Cantor. 1995. Recombinant Core Streptavidins. J. Bio. Chem., 47:28204-28209.

    147. Smith, C. L. 1995. Editorial “The New Genetic Fusion Science” Genetic Analysis: Biomolecular Engineering, 12:71.

    148. Yaar, R., P. Szafranski, C. R. Cantor and C. L. Smith. 1996. In situ Detection of Tandem Repeat Length” Genetic Analysis (Biomolecular Engineering), 13:113-118.

    149. Sano, T., Vajda, S, Reznik, G. O., Smith, C. L. and Cantor, C. R. 1996. Molecular Engineering of Streptavidins. Annals of NY Acad. of Sci., 799:383-390.

    150. Lagutina, I. V., E. V. Yurkova, T. L. Azhikina, V. V. Demin, C. L. Smith and E. D. Sverdlov. 1996. Determination of the patterns of hexanucleotide distribution along the DNA by Electron Miscroscopy. Genetic Analysis (Biomolecular Engineering), 13:9-14.

    151. Smith. C. L., Oliva R., Lawrence, S. K. and Wang, D. 1997. Chromosomes, Molecular Studies. In, Encyclopedia of Human Biology, 2nd Edition. Ed. R. Dulbecco. Academic Press, San Diego, pp. 781-796.

    152. Koster, H., K. Tang, D.-J. Fu, A. Braun, D. Van den Bloom, C.L. Smith, R.J. Cotter, and C.R. Cantor. 1996. A Strategy for Rapid and Efficient DNA Sequencing by Mass Spectrometry. Nature Biotech., 14:1123-1128.

    153. Reznik, G. O., S. Vajda, C. L. Smith, C. R. Cantor and T. Sano. 1996. Streptavidins with Intersubunit Crosslinks: Introduction of Covalent Bonds Between Subunits through the Dimer-dimer Interface Enhances the Overall Stability of Streptavidin. Nature Biotechnology, 14:1007-1011.

    154. Bukanov, N, D. Wang and C. L. Smith. 1996. Human Chromosomes, Physical Maps of. In, Encyclopedia of Molecular Biology and Molecular Medicine, R. A. Meyers (ed.) VCH, New York, Vol. 4, pp. 215-221.

    155. Sano, T., G. O. Reznik, P. Szafranski, C. M. Niemeyer, S. Vajda, C. L. Smith, C. M. Mello, D. L. Kaplan, M. Rusckowski, D. J. Hnatowich and C. R. Cantor. 1996. Steptavidin: a Genetically Engineered Biological Lock and Key. In, Proceedings of the 50th Anniversary Conference of the Korean Chemical Society, Korean Chemical Society, Seoul, Korea., pp.359-363.

    156. Sano. T., C. L. Smith and C. R. Cantor. 1997. Deoxyribonucleic Acids as Unique Markers in Molecular Detection. Genetic Analysis (Biomolecular Engineering) 14:37-40.

    157. Sano, T., C. L. Smith and C. R. Cantor. 1997 Expression and Purifaction of Steptavidin-containing Chimeric Proteins. Methods Mol. Biol., 63:119-128.

    158. Szafranski, P., C. M. Mello, T. Sano, C. L. Smith, C. R. Cantor and D. L. Kaplan. 1997. A New Approach to Containment of Microorganisms Based on Steptavidin Gene Expression Tighlty Regulated by Antisense RNA and T7 Transcription System. Proc. Natl. Acad. Sci., 94:1059-1063.

    159. Cantor, C.R., T. Sano, N. E. Broude and C. L. Smith. 1997. Instrumentation in Molecular Biomedical Diagnostics: An Overview. Genetic Analysis (Biomolecular Engineering, 14:31-36.

    160. Broude, N., A. Chandra and C. L. Smith. 1997. Differential Display of Genome Subsets Containing Specific Interspersed Repeats. Proc. Nat. Acad. Sci., 94:4548-4553.

    161. Kong, H. and C. L. Smith. 1997. Substrate DNA and Cofactor Regulate the Activities of a Multi-Functional Restriction Modification Enzyme, BcgI. Nucleic Acid Res. 25:3687-3692

    162. Sano, T., S. Vajda, C. L. Smith and C. R. Cantor. 1997. Engineering Subunit Association of Multisubunit Proteins: A Dimeric Streptavidin. Proc. Natl. Acad. Sci., 94:6153-6158.

    163. Fu, D. J., H. Kˆster, C. L. Smith and C. R. Cantor. 1997. Sequencing Double-Stranded DNA by Strand Displacement. Nucl. Acids Res., 25: 677-679.

    164. Sano, T., C. L. Smith and C. R. Cantor. 1996. Immuno-PCR. In, The Encyclopedia of Molecular Biology and Biotechnology, Robert A. Meyers, Ed. VCH Publishers Inc., New York City, N. Y., Vol 4, pp. 288-295.

    165. Cantor, C. R., P. Szafranski, T. Sano, C. M. Mello, C. L. Smith and D. L. Kaplan. 1996. Streptavidin-based conditional lethal system for biological containment of Pseudomonas putida. In Global Environmental Biotechnology, ed. by D.L Wise, Elsevier Science, Amsterdam, The Netherlands, pp. 201-204

    166. Szafranski, P., C. L. Smith and C. R. Cantor. 1997. Cloning and Analysis of the dnaG gene Encoding Pseudomonas putida DNA Primase. Biochim. Biophy. Acta, 1352:243-248.

    167. O’Donnell-Maloney, M. J., C. L. Smith and C. R. Cantor. 1996. The development of microfabricated arrays for DNA sequencing and analysis. TIBTECH, 14:401-407.

    168. Sano, T., G. Reznik, S. Vajda, C. R. Cantor and C. L. Smith. 1997. Properties and Applications of Genetically Engineered Streptavidins. In, Scientific and Clinical Applications of Magnetic Carriers, ed. By U. Hafeli, W. Schutt, J. Teller, and M. Zborowski, Plenum Press, New York, NY. pp. 295-301.

    169. Smith, C. L. and Cantor, C. R. 1997. Consequences of Mapping and Sequencing the Human Genome for Neurologic Diseases. In, The Molecular and Genetic Basis of Neurological Disease, 2nd Edition. eds. Rosenberg, R. N., Prusiner S. B., DiMauro S and Barchi, R. L. Butternworth Heinemann, Newton, MA. pp. 1375-1388.

    170. Graber, J. H, D. J. Fu, H. Koester, C. L. Smith and C. R. Cantor. 1997. Optimizing Spectrometry Based Genetic Mutation Localization and Identification. Mathematical Modeling and Scientific Computing. in press

    171. Cantor, C. R., Tang, K., Graber, J. H., Maloney, M. J., Fu, D.-J., Broude, N. E., H. Koester, and Smith, C. L. 1997. DNA sequencing after the human genome project. Nucleosides and Nucleotides. 16:591-598.

    172. O”Donnell, M. J., K. Tang, H. Koester, C. L. Smith and C. R. Cantor. 1997. High Density, Covalent Attachment of DNA to Silicon Wagers for Analysis by MALDI-TOF Mass Spectrometry., Anal. Chem. 69:2438-2443.

    173. Kong, H. and C. L. Smith. 1998. BcgI Preferentially Cleaves DNA Substrates with Multiple Copies of Its Recognition Rite. Biological Chemistry., 379:605-609.

    174. Graber, J. H., O’Donnell, M. J., Smith, C. L. and Cantor, C. R. 1998. Advances in DNA diagnostics. Current Biology, 1:14-18.

    175. Oliveira, R. P., N. E. Broude, A. M. Macedo, C. R. Cantor, C. L. Smith and S. D. J. Pena. 1998. Probing the genetic population structure of Trypanosoma cruzi with polymorphic microsatellites. Proc. Nat. Acad. Sci., 95:3776-3780.

    176. Smith, C. L., T. Sano, N. E. Broude and C. R. Cantor. 1999. Parallel Strategies for DNA Manipulation Analysis. American Mathematical Society, 47:199-211.

    177. Hatch, A., T. Sano, J. Misasi and C. L. Smith. 1999. Mutation Detection using Rolling Circle Amplification (RCA) and Immobilized DNA probes. Genetic Analysis (Biomolecular Engineering), 15:35-40.

    178. Graber, J., C. R. Cantor and C. L. Smith 1999. Genetic Mutation Screening by Mass Spectrometry. Genetic Analysis (Biomolecular Engineering), 14:215-220.

    179. Cantor, C. R. and C. L. Smith. 1999. Genomics: The Science and Technology Behind the Human Genome Project. Wiley and Sons, Inc. NY, pp.1-596

    180. Smith, C. L. 1999. The Meaning of DNA Sequence Variation: A Next Step in Dissection of the Human Genome. Genetic Analysis: (Biomolecular Engineering), 14:4.

    181. Lavrentieva, I., N. Broude, Y. Lebedev, I. I. Gottesman, S. A. Lukyanov, E. Sverdlov, and C. L. Smith. 1999. High polymorphism level of genomic sequences flanking insertion sites of human endogenous retroviral long terminal repeats. FEBS Letters, 443:341-347.

    182. Surdi, G., R. Yaar and C. L. Smith. 1999. Discrimination of DNA Duplexes with Matched and Mismatched Tandem Repeats by T4 Endonuclease. Genetic Analysis (Biomolecular Engineering), 14:177-180.

    183. Broude, N., N. Storm, S. Malpel, J. H. Graber, S. Lykyanov. E. Sverdlov and C. L. Smith. 1999. PCR Based Targeted Genomic and cDNA Differential Display. Genetic Analysis (Biomolecular Engineering), 52:51-63.

    184. Bouchard, J., Foulon, C., G. Nyugen, N. Storm and C. L. Smith. 1998. Genomic Discordance in Mongozygotic Twins. In, “Techniques in the Behavioral and Neural Sciences”, Eds. W. Crusio and R. Gerlai, Elsevier, Amsterdam, The Netherlands, 13: 237-256.

    185. Tolstoi, L and C. L. Smith. 1999. Human Genome Project and Cystic Fibrosis – a Symbiotic Relationship. Journal of American Dietetic Association, 89(11): 1421-1427.

    186. Smith, C. L. 1999. An Embargoed Cuban Science. Genetic Analysis (Biomolecular Engineering), 15:71-72.

    187. Tolstoi, L. and C. L. Smith. 1999. The Biotechnology Revolution: A Primer for Pharmacists. Hospital Pharmacy, 34:1401-1408.

    188. Yun, W., J. G. Smits, P. Dominguez, C.R. Cantor and C.L. Smith. Current Voltage Measurements of Thin Film Piezoelectric Zinc Oxide. submitted to Journal of Electroceramics, in press

    189. Sabayanayam C., C. Berkey, U. Lavi, C.R. Cantor and C. L. Smith 1999. Molecular Switches and DNA Chips. SPIE 3606: 90-97

    190. Kaplan, D.L., C. Mello, T. Sano, C. Cantor and C. Smith. 1999. Streptavidin-based Containment Systems for Genetically Engineered Microorganisms. Biomolecular Engineering, 16:135-140.

    191. Smith, C. L. and N. Laton. 1999. What is Biomolecular Engineering? Biomolecular Engineering. 16: vii-viii.

    192. Smith, C. L. 2000. Introduction to DNA Analysis. In, “Encyclopedia of Analytical Chemistry: Instrumentation and Applications”, Ed. R. A. Meyers, John Wiley & Sons, Lmt. Sussex, UK, 6:4847-4848.

    193. Smith, C. L., G. Nguyen, J. Bouchard, G. Surdi, R. Yaar and L. Tolstoi. 2000. Comparative Genomics: Differential Display and Subtractive Hybridization. In, “Encyclopedia of Analytical Chemistry: Instrumentation and Applications”, Ed. R. A. Meyers, John Wiley & Sons, Lmt. Sussex, UK, 6:4893 – 4901.

    194. Sabayanayam, C., C. R. Cantor and C. L. Smith. 2000. Oligonucleotide Immobilization on Micropatterned Streptavidin Surfaces. Nucleic Acids Res., 28:e33.

    195. Smith, C. L. and L. Tolstoi. 2001. Genomics. In, ìBiology for Studentsî, eds. P. J. Bruns, R. Chisholm, M. A Davis, T. M. Frost, K. S. Saladin, Macmillion Reference USA, Farmington Hills, MI, pp. 141-145

    196. Oleszczuk, J. J., G. A. Machin, D. M. Keith, C. L. Smith and L. G. Keith. 2001. Zygosity of Twins: Is It Time for a New Terminology? In, Ginekologia Polska, in press

    197. Keith, L. G., J. J. Oleszczuk, G. A. Machin, C. L. Smith and D. M. Keith. Controversies and Potential Solutions for Zygosity Assessments,

    HYPERLINK “http://www.obgyn.net/displayarticle.asp?page=/first”

    http://www.obgyn.net/displayarticle.asp?page=/first

    controversities/prague1999keith-etal

    198. Smith, C. L. 2001. The Experts at Hadamar, Biomolecular Engineerng. 17:39

    199. Nguyen, G., J. Bouchard, C. Foulon, L. Keith, C Baldwin, and VH Herrera and C. L. Smith. 2003. Genomic Instability and Schizophrenia in Monozygotic Twins. Am. J. Medical Genetics (Neuropsychiatric Genetics). 120B:1-10.

    200. Abdolmaleky, H. M., C. L. Smith, Ph. D, S. V. Faraone, R. Shafa, W. Stone, S. Glatt and M. Tsuang, 2004. Methylomics in Psychiatry: Modulation of Gene-Environment Interaction by DNA Methylation. Am. J. Medical Genetics (Neuropsychiatric Genetics). 127B: 51-59.

    201. Smith, C. L. 2004. Book review of “Gene Expression: Handbook of Methods, Possibilities, and Pitfall” Editors: S. Lorkowski and P. Cullen (eds) vol 1 and 2, Wiley-VCH Verlag, GmbH & Co, Kga, Weinheim, Germany. Biomolecular Engineering, 21:123.

    202. Smith, C. L. 2004. Identical Twins and Siblings: The Limits of Current DNA Testing. DNA NetLetter 56: (http://www.lexis.net)

    203. Abdolmaleky H, M., K.-H Cheng, A. Russo, C. L. Smith, S. V. Faraone, R. Shafa, M. Wilcox, S. Glatt, W. S. Stone, G. Nguyen, J. F. Ponte, S. Thiagalingam and M. Tsuang. 2005. Hypermethylation of the RELN Promoter in the Brain of Schizophrenic Patients: A Preliminary Report. Am. J. Medical Genetics (Neuropsychiatric Genetics) 134: 60-66.

    204. Nguyen, G., N. Bukanov, M. Oshimura and C. L. Smith 2005. Cloneless Genomic DNA Analysis: An Efficient and Simple Alternative to Clone Libraries for de novo Genomic Sequencing and Gap Filling. Biomolecular Engineering. 21: 135-144.

    205. Smith, C. L., G. Nguyen, D. Wang and N. Bukanov. 2005. Whole Genome Human Chromosome Physical Mapping. In, Encyclopedia of Molecular Biology and Molecular Medicine, R. A. Meyers (ed.) VCH, New York, pp 555-572.

    206. Abdolmaleky, H. M., K.-H. Cheng , S. V.Faraone, M. Wilcox, A. Russo, C. L. Smith, S. J. Glatt, R. Shafa,, J. Ponte, M. Tsuang and S. Thiagalingam. 2006. Hypomethylation of the COMT Gene Promoter in Brain Tissue is a Risk Factor for Schizophrenia. Human Molecular Genetics 15:3135-3145.

    207. Nguyen, H. G., S. Milea, A. Rai, and C. L. Smith, 2005. Mild Conditions for Releasing Mono- and Bis- Biotinylated Macromolecules from Immobilized Streptavidin. Biomolecular Engineering. 22: 147-150.

    208. Nguyen, G, N. Nguyen, N. Storm, H. Gavras and C. L. Smith. 2006. Targeted cDNA Differential Display. Biomolecular Engineering 23: 41-54.

    209. Smith, C. L., S. Milea, and G. H. Nguyen. 2006. Immobilization of Nucleic Acids using Biotin-Strept(avidin) Systems. In, Topics in Current Chemistry. C. Whittman (ed.) Springer-Verlag, GmbH&Co.KG, Heidelberg, 63-90.

    210. Smith, C. L., G. Nguyen, D. Wang and N. Bukanov. 2007. Whole Genome Human Chromosome Physical Mapping. In, Genomics and Genetics, R. A. Meyers (ed.) VCH, New York, pp 667-692.

    211. Abdolmaleky, H. M., C. L. Smith, J.-R. Zhou, and S. Thiagalingam. 2007. Epigenetic Modulation of Reelin Function in Schizophrenia and Bipolar Disorder. In, Reelin Glycoprotein, Biology, Structure and Roles in Health and Disease. S. H. Fatemi (ed). Springer, in press.

    212. Smith, C. L. 2007. Third Annual CNS Disease Congress: Fifth Annual Psychiatric Disorders. Thomson Pharma (http://www.thomson.com/scientific//solutions).

    213. Nguyen, C. P. N., C. H. Nguyen, Nguyen, C. T. H. G. and C. L. Smith 2007. Ferrite nanoparticles immobilized oligonucleotide and digested DNA of Crinum latifolium L. ICCE, in press.

    214. Abdolmaleky H.M., Smith CL, Zhou, R.J.Thiagalingam S. 2008. in “Epigenetic Alterations of Dopaminergic System in Major Psychiatric Disorders” book chapter for “Pharmacogenomics in Drug Discovery and Development” Methods Mol. Bio. 448:187-212.

    215. Abdolmaleky, H. G., R. J. Zhou, S. Thiagalinagam C. L. Smith. 2008. Epigenomic studies of major psychosis and the potentials for therapeutics. Future of Medicine: Pharmacogenomics, 9(12): 1809-23.

    216. Shafa. R.,,H. M. Abdolmaleky, S. Yaqubi, M.D., C. L Smith, S. N. Ghaemi, 2009

    COMT- Inhibitors may be a promising tool in treatment of Marijuana addiction

    American Journal of Addiction, in press.
    217. Ahmadkhaniha, H. R., Mokri, B., Naserbakht, M, Abdolmaleky, H. M.and C. L. Smith. 2009. Advanced Paternal Age is a Risk Factor for Schizophrenia in a Cross-Sectional Population Study of Iranians. submitted

    218. Becsktead, W., J. Campbell, J. Brothers II, A. Bolton, and C. L. Smith 2008. Schizogad: Database of genes linked to schizophrenia. (http://www.schizogad.bu.edu).