Brunett, J.R., Zhong, S., Jiang, Z.G., Hooper, A.J., Fisher, E.A., McLeod, R.S., Zhao, Y., Barrett, H.R., Hegele, R.A., van Bockxmeer, F.M., Zhang, H., Vance, D.E., McKnight, C.J., & Yao, Z. (2007) Missense mutations in ApoB within the beta-alpha-1 domain of human ApoB-100 result in impaired secretion of apoB and ApoB-containing lipoproteins in familial hypobetalipoproteinemia, J. Biol. Chem., 282, 24770-24283.
[PubMed Abstract]
Smirnov, S.L., Isern, N.G., Jiang, Z.G., Hoyt, D.W. & McKnight, C.J. (2007) The isolated sixth gelsolin repeat and headpiece domain of villin bundle F-actin in the presence of calcium and are linked by a 40-residue unstructured sequence, Biochemistry, 46, 7488-7496.
[PubMed Abstract]
Latz, E., Verma, A., Visintin,A., Gong, M., Sirois, C.M., Klein, D., Monks, B.G., McKnight, C.J., Duprex, W.P., Espevik, T., & Golenbock, D.T. (2007) Ligand induced conformational changes in TLR9 result in allosteric receptor activation, Nature Immunology , 8, 772-779.
[PubMed Abstract]
Jiang, Z.G., Simon, M.N., Wall, J.S., & McKnight, C.J., (2007) Structural analysis of reconstituted lipoproteins containing the N-terminal domain of apolipoprotein B, Biophysical Journal , 92, 4097-4108.
[PubMed Abstract]
Jiang, Z.G., Gantz, D., Bullitt, E., & McKnight, C.J., "Defining lipid interacting domains in the N-terminal region of apolipoprotein B," Biochemistry, 2006, 45, 11799-11808.
[PubMed Abstract]
Jiang, Z.G. & McKnight, C.J. "A phosphorylation induced change in dematin headpiece," Structure, 14, 379-387, 2006.
[PubMed Abstract]
Grey M.J., Tang Y., Alexov E., McKnight C.J., Raleigh D.P., & Palmer AG III. "Characterizing a partially folded intermediate of the villin headpiece domain under non-denaturing conditions: Contribution of His41 to the pH-dependent stability of the N-terminal subdomain," J Mol Biol., 355, 1078-1094, 2006.
[PubMed Abstract]
Tang Y., Grey M.J., McKnight J., Palmer A.G. III, & Raleigh D.P. "Multistate folding of the villin headpiece domain," J Mol. Biol., 335, 1066-107, 2006.
[PubMed Abstract]
McKnight, C.J. & Cordes, M.J.H., "Networking at the Protein Society Meeting," Nature Chem. Biol.,1, 239-242, 2005.
[PubMed Abstract]
Meng, J., Vardar, D., Wang, Y., Guo, H.-C., Head, J.F. & McKnight, C.J. "The high resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity," Biochemistry, 44, 11963-73, 2005.
[PubMed Abstract]
Jiang, Z.G., Carraway, M. & McKnight, C.J., "Limited proteolysis and biophysical characterization of the lipovitellin homology region in apolipoprotein B," Biochemistry , 44, 1163-1173, 2005.
[PubMed Abstract]
Frank, B. S., Vardar, D., Chishti, A. H. & McKnight, C. J., "The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal site." J Biol. Chem., 279, 7909-7916, 2004.
[PubMed Abstract]
Burnett, J.R., Shan, J., Miskie, B.A., Hooper, A.J., Yuan, J., Tran, K., McKnight, C.J., Yao, Z., Hegel, R.A.,, "A novel non-truncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia," J. Biol. Chem., 278, 13442-13452, 2003.
[PubMed Abstract]
Wang, M., Tang, Y. Satoshi, S., Vugmeyster, L., McKnight, C.J. and Raleigh, D.P., "Dynamic NMR lineshape analysis demonstrates that the villin headpiece subdomain folds on the microsecond time scale,"
J. of the American Chemical Society, 125, 6032-3, 2003.
[PubMed Abstract]
Cordes, M.H.J., Walsh, N.P., McKnight, C.J., Sauer, R.T. , "Solution structure of switch Arc, a mutant with 3-10 helices replacing a wild-type beta-ribbon," J. Molecular Biology, 326, 899-909, 2003.
[PubMed Abstract]
L. Vugmeyster, O. Trott, C.J. McKnight, D.P. Raleigh, & A.G. Palmer
III, "Temperature dependent dynamics of the villin headpiece helical
subdomain, an unusually small thermostable protein," J. Molecular Biology, 320, pp. 841-54, 2002.
[PubMed Abstract]
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D.Vardar, A.H. Chishti, B.S. Frank, E.J. Luna, A.A. Noegel, S.W. Oh, M.
Schleicher, & C.J. McKnight, "Villin-type headpiece domains show a
wide range of F-actin-binding affinities," Cell Motil Cytoskeleton, 52, pp. 9-21, 2002.
[PubMed Abstract]
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B.S. Frank, D. Vardar, D.A. Buckley, & C.J. McKnight, "The role of
aromatic residues in the hydrophobic core of the villin headpiece
subdomain," Protein Science, 11, pp. 680-7, 2002.
[PubMed Abstract]
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J. Grogan, C.J. McKnight, R.F. Troxler, & F.G. Oppenheim, "Zinc and copper bind to unique sites of histatin 5," FEBS Letters, 491, pp. 76-80, 2001.
[PubMed Abstract]
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H. Herscovitz, A. Derksen, M.T. Walsh, C.J. McKnight, D.L. Gantz, M.
Hadzopoulou-Cladaras, V. Zannis, C. Curry, & D.M. Small, "The
N-terminal 17% of apoB binds tightly and irreversibly to emulsions
modeling nascent very low density lipoproteins," J. Lipid Research, 42, pp. 51-59, 2001.
[PubMed Abstract]
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M.H.J. Cordes, R.E. Burton, N.P. Walsh, C.J. McKnight, & R.T. Sauer, "An evolutionary bridge to a new protein fold," Nature Structual Biology, 12, pp., 1129-1132, 2000.
[PubMed Abstract]
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D. Vardar, D.A. Buckley, B.S. Frank, & C.J. McKnight, "NMR structure of an F-actin-binding "headpiece" motif from villin." J. Molecular Biology, 294, pp. 1299-1210, 1999.
[PubMed Abstract]
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M.H.J. Cordes, N.P. Walsh, C.J. McKnight, & R.T. Sauer, "Evolution of a protein fold in vitro,"
Science, 284, pp. 325-327, 1999.
[PubMed Abstract]
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C.J. McKnight, P.T. Matsudaira, & P.S. Kim, "NMR structure of the 35-residue villin headpiece subdomain," Nature Structural Biology, 4, pp. 180-184, 1997.
[PubMed Abstract]
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C.J. McKnight, D.S. Doering, P.T. Matsudaira, & P.S. Kim, "A thermostable subdomain within villin headpiece," J. Molecular Biology, 260, pp.126-134, 1996.
[PubMed Abstract]
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