1. Martin, G.R., Byers, P.H., and Smith, B.D. On the nature of polypeptide
precursors of collagen. Kulonen, E. and Pikkarainen, J. (eds.): Biology of the
. Academic Press, New York, 339-342, 1973.
2. Smith, B.D., Martin, G.R., Miller, E.J., Dorfman, A., and Swarm, R. Nature of
the collagen synthesized by a transplanted chondrosarcoma. Arch. Biochem.
166:181-186, 1975.
3. Lichtenstein, J.R., Byers, P.H., Smith, B.D., and Martin, G.R. Identification of the
collagenous proteins synthesized by cultured cells from human skin. Biochemistry
14:1589-1594. 1975.
4. Smith, B.D., McKenny, K.H., and Lustberg, T. The characterization of collagen
precursors found in rat skin and rat bone. Biochemistry 16:2980-2985, 1977.
5. Moro, L. and Smith, B.D. Identification of collagen alpha 1(I) trimer and normal
type I collagen in a polyoma virus induced tumor. Arch. Biochem. Biophys.
182:3-41, 1977.
6. Yue, B.Y.J.T., Baum, J.L., and Smith, B.D. Collagen synthesis by cultures of
stromal cells from normal human and keratoconus corneas. Biochem. Biophys.
Res. Commun.
86:465-472, 1979.
7. Smith, B.D., Biles, D., Gonnerman, W., Faris, B., Levine, A., Capparell, N.,
Moolten, F., and Franzblau, C. Collagen synthesis in normal BHK cells and
temperature sensitive chemically transformed BHK cells. In Vitro 15:455-462,
8. Smith, B.D. and Niles, R. Characterization of collagen synthesized by normal and
chemically transformed rat liver epithelial cell lines. Biochemistry 19:1820-1825,
9. Beldekas, J., Smith, B.D., Gerstenfeld, I.C., Sonenshein, G.E., and Franzblau, C.
Effects of 17-Beta estradiol on the biosynthesis of collagen in cultured bovine
aortic smooth muscle cells. Biochemistry 20:2162-2167, 1981.
10. Smith, B.D. and Silbert, C.K. Fibronectin and collagen of cultured skin
fibroblasts in diabetes mellitus. Biochem. Biophys. Res. Commun., 100:
100:275-282, 1981.
11. Yue, B.Y.J.T., Baum, J.L., and Smith, B.D. Collagens synthesized by normal
corneal and keratoconus cells. Biochim. et Biophys. Acta. 75:318-325, 1983.
12. Senger, D.R., Asch, B.B., Smith, B.D., Perruzzi, C.A., and Dvorak, H.F.
Secreted phosphoprotein associated with neoplastic transformation of both
epithelial and fibroblastic cells. Nature (London) 302:714-715, 1983.
13. Smith, B.D., Mahoney, A.P., and Feldman, R.S. The inverse correlation of
collagen production to anchorage independence. Cancer Res. 43:4275-4282,
14. Marsilio, E., Sobel, M.E., and Smith, B.D. Absence of procollagen a2(I)
mRNA in chemically transformed rat liver epithelial cells. J. Biol. Chem.
259:1401-1404, 1984.
15. Dvorak, H.F., Form, D.M., Manseau, E.J., and Smith, B.D. Pathogenesis of
Desmoplasia. I. Immunofluorescence identification and localization of some
structural proteins of line 1 and line 10 guinea pig tumors and of healing wounds. J.
Natl. Cancer Institute
73:1195-1205, 1984.
16. Form, D.M., Van DeWater, L., Dvorak, H.F., and Smith, B.D. Pathogenesis
of tumor desmoplasia. II. Collagens synthesized by line 1 and line 10 guinea pig
carcinoma cells and by syngeneic fibroblasts in vitro. J. Natl. Canc. Inst.
73:1207-1214, 1984.
17. Cronlund, A.L., Smith, B.D., and Kagan, H.M. Binding of lysyl oxidase to
fibrils of type I collagen. Connective tissue Research, 14:109-119, 1985.
18. Smith, B.D., and Marsilio, E. Methylation of the a2(I) Collagen gene in
chemically transformed rat liver epithelial cells. Biochem. J 253:269-273, 1988.
19. Lee, S.-T., Smith, B.D., and Greenspan, D.S. Construction of a full-length
cDNA encoding human pro-
a2(I) collagen and its expression in pro- a2(I)-
deficient W8 rat cells. J. Biol. Chem. 263:13414-13418, 1988.
20. Smith, B.D. and Baldwin, C. T. Undifferentiated F9 embryonal carcinoma cell
produce a short chain collagen molecule. Biochem J. 255:85-89, 1988.
21. Goldstein, R.H., Poliks, C.F., Pilch, P.F., Smith, B.D., and Fine, A. Stimulation
of collagen formation by insulin and insulin-like growth factor-I in cultures of
human lung fibroblasts Endocrinology 124:964-970, 1989.
22. Baldwin, C.T., Silbert, J.E., Humphries, D.E., Cogburn, J.N., and Smith, B.D.
Increased proteoglycan synthesis following the differentiation of F9 embryonal
carcinoma cells: formation of a differentiation specific proteoheparan sulfate.
Matrix and Related Research 9:389-306 1989.
23. Fine, A., Poliks, C.F., Donahue, L. P., Smith, B.D., and Goldstein, R.H. The
differential effect of PGE2 on TGF-
b and insulin-induced collagen formation in
lung fibroblasts J. Biol. Chem. 264:16988-16991, 1989.
24. Smith, B.D. Mechanisms for non-coordinate expression of type 1 collagen alpha
chains: in Structure, Molecular biology and pathology of collagen Annals NY
Acad Sci
580:459-461, 1990.
25. Fine, A., Poliks, C.F., Smith, B.D., and Goldstein, R.H. The accumulation of
Type I collagen mRNAs in human embryonic lung fibroblasts stimulated by
transforming growth factor-
b . Connective Tissue Research 24:237-247,
26. Ritzenthaler, J.D., Goldstein, R.H., Fine, A., Lichtler, A., Rowe, D.W., and
Smith, B.D. Transforming Growth Factor-
b responsive elements in the distal
promoter regions of the rat
a1(I) collagen gene. Biochem. J. 280:157-162,
27. Guenette, D., Ritzenthaler, J. D., , Foley, J., Jackson, J., and Smith, B. D.
Alterations in rat and human
a2(I) promoter by DNA methylation Biochem. J.
286:699-703, 1992.
28. Fine, A., Matsui, R., Zhan, X., Poliks, C.F., Smith, B.D., and Goldstein, R.H.
Discordant regulation of human type I collagen genes by prostaglandin E2
Biochem. Biophys. Acta, 1135:67-72, 1992.
29. Ritzenthaler, J. D., Goldstein, R. H., Fine, A. and Smith, B. D. Regulation of the
a1(I) collagen promoter via a TGF-b activation element. J. Biol. Chem.
268:13625-13631, 1993.
30. Minto, A.W., Fogel, M.A., Natori, Y., O'Meara, Y.M., Abrahamson, D.R.,
Smith, B.D., and Salant, D.J., Expression of type I collagen mRNA in glomeruli of
rats with passive Heymann nephritis. Kidney International 43:121-127, 1993.
31. Lim, A.L., Greenspan, D.S. and Smith, B.D. Expression of a2 type I collagen
in W8 cells increases cell adhesion and decreases colony formation in soft agar.
Matrix Biology 14:21-30, 1994.
32. Fine, A.,Panchenko, M.P., Smith, B.D., Yu, Q. and Goldstein, R.H.
Discordant regulation of transforming growth factor-
b receptors by prostaglandin
E2 Biochem. Biophys. Acta,111261:19-24, 1995
33. Moreland, R.B., Traisch, A., McMillin, M.A., Smith, B., Goldstein, I., and
Saenz de Tajada, I. PGE1 suppresses the induction of collagen synthesis by
transforming growth factor-
b in human corpus cavernosum smooth muscle J.
153:826-834, 1995.
34. Lucey, E.C., Ngo, Hiep Q., Agarwal, A., Smith, B.D., Snider, G.L, and
Goldstein, R.H. Differential expression of elastin and
a1(I) collagen mRNA in
mice with bleomycin-induced pulmonary fibrosis. Lab Invest. 74:12-20, 1996.
35. Agarwal, A., Ngo, H.Q., Goldstein, R.H., Lucey, E., and Smith B.D., Cell
specific expression of the
a1(I) promoter-CAT transgene in skin and lung: A
response to TGF-
b subcutaneous injection and bleomycin endotracheal
instillation J. Cell Biochem 63:135-148, 1996.
36. Lim, A.L, Doyle, Sharon A. Balian, G., and Smith, B.D. The role of the pro-
a2(I) COOH-terminal region in assembly of type I collagen: Truncation of the last
tem amino acid residues of pro-
a2(I) chain prevents the assembly of type I
collagen heterotrimer. J. Cell Biochem. 71:216-232, 1998.
37. Doyle, S.A. and Smith B.D. The role of the pro-a2(I) COOH-terminal region in
assembly of type I collagen: Disruption of two intramolecular disulfide bonds in
a2(I) blocks assembly of type I collagen. J. Cell Biochem. 71:216-232,
38. Sengupta, P.K. and Smith, B.D. Methylation in the initiation region of the first
exon suppresses collagen pro-
a2(I) gene transcription. Biochem Biophys Acta,
93183:1-15, 1998.
39. Smith, B., Expression and Regulation of the Collagen Family in Skin, in Wound
Healing and the Skin
, Falanga, V., Ed., Martin Dunitz Limited, London, UK (in
40. Sengupta, P.K. and Smith, B.D. A methylation responsive methylated DNA-
binding protein/ Regulatory factor X MDBP/RFX site is in the exon of the collagen
a2(I) gene. J. Biol Chem 274:36649-36655, 1999.
41. Stoddart, J.H., Harmon, M.H., Hou, F.X., Pritzker, C., Bronson, R., and
Smith, B.D. Transgenic Mice with a Mutated alpha 1(I) Collagen Promoter have a
Diminished Response to Bleomycin and Display Neurological Abnormalities. J.
Cell Biochem
77:135-148, 2000.
42. Sun, W., Hou, F., Panchenko, M.P. and Smith, B.D. A member of the Y-box
protein family interacts with an upstream element in the
a1(I) collagen gene.
Matrix In press.