Multimodal Imaging of Neurodegenerative Dementias & Brain Aging Integrative Neurosciences Lab

 

Mission Statement

To use a multidisciplinary and collaborative approach, the tools of computational modeling, clinical pharmacology, and cognitive neuroscience to link ideas, integrate knowledge, and devise novel approaches and quantitative solutions that translate clinically to optimize brain aging and cognitive functions, and affect improvements in the diagnosis, care and treatment of patients with cognitive impairments, dementia and Alzheimer’s disease.

Our goals are:
1. To gain a greater understanding of the dynamics and optimal functioning of the networks that support human memory and learning;
2. To better understand network structure-function relationships and the effects of the aging process and neurodegenerative dementias on memory and learning systems;
3. To develop quantitative methods that allow creation, integration and optimization of noninvasive, sensitive and accurate pharmaco-neuroimaging biomarkers for detecting, staging, and tracking neurodegenerative dementias;
4. To construct computational models that allow prediction of clinical course, and treatment response and optimization at the level of the individual, and
5. To create an open and positive environment that:
a. Is team-oriented, multidisciplinary, collaborative, inquisitive, intellectually stimulating, fun and supportive;
b. Prioritizes the physical, emotional and spiritual health and well-being of our patients, subjects, veterans, volunteers, collaborators, and team-members, and
c. Promotes the philosophy of advancing knowledge, medicine and science in a manner that fulfils purpose and creates meaning.

PEOPLE
PI: Alireza (Ali) Atri, M.D., Ph.D.
Lab Members:
Jessica Dodd, B.A.
Michael Flaherty, B.S.
Lynn (Lili) Shaughnessy, B.S.
Aishwarya Sreenivasan, M.S.
Associate Lab Members:
Kiran Reddy, M.D., M.B.A.
Joseph Locascio, Ph.D.